Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ALX-804-022-R100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-022-R100, RRID:AB_2052029
- Product name
- NF-ATc1 monoclonal antibody (7A6)
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein fragment
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 7A6
- Vial size
- 100 μl
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Activity- and calcineurin-independent nuclear shuttling of NFATc1, but not NFATc3, in adult skeletal muscle fibers.
Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3.
Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells.
Calcium-dependent activation of interleukin-21 gene expression in T cells.
Vasopressin-dependent myogenic cell differentiation is mediated by both Ca2+/calmodulin-dependent kinase and calcineurin pathways.
Blockade of nuclear factor of activated T cells activation signaling suppresses balloon injury-induced neointima formation in a rat carotid artery model.
Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis.
Interleukin (IL)-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms.
IL-4-induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation.
NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching.
Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells.
Role of NFAT proteins in IL13 gene transcription in mast cells.
Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production.
Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kappa B proteins.
Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells.
The basis for TCR-mediated regulation of the IL-2 receptor alpha chain gene: role of widely separated regulatory elements.
Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation.
Cannabinol enhancement of interleukin-2 (IL-2) expression by T cells is associated with an increase in IL-2 distal nuclear factor of activated T cell activity.
The calcineurin-NFAT pathway and muscle fiber-type gene expression.
Expression of NFAT-family proteins in normal human T cells.
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells.
NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity.
Shen T, Liu Y, Cseresnyés Z, Hawkins A, Randall WR, Schneider MF
Molecular biology of the cell 2006 Apr;17(4):1570-82
Molecular biology of the cell 2006 Apr;17(4):1570-82
Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3.
Wu W, Misra RS, Russell JQ, Flavell RA, Rincón M, Budd RC
The Journal of biological chemistry 2006 Apr 21;281(16):10682-90
The Journal of biological chemistry 2006 Apr 21;281(16):10682-90
Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells.
Proksch P, Giaisi M, Treiber MK, Palfi K, Merling A, Spring H, Krammer PH, Li-Weber M
Journal of immunology (Baltimore, Md. : 1950) 2005 Jun 1;174(11):7075-84
Journal of immunology (Baltimore, Md. : 1950) 2005 Jun 1;174(11):7075-84
Calcium-dependent activation of interleukin-21 gene expression in T cells.
Kim HP, Korn LL, Gamero AM, Leonard WJ
The Journal of biological chemistry 2005 Jul 1;280(26):25291-7
The Journal of biological chemistry 2005 Jul 1;280(26):25291-7
Vasopressin-dependent myogenic cell differentiation is mediated by both Ca2+/calmodulin-dependent kinase and calcineurin pathways.
Scicchitano BM, Spath L, Musarò A, Molinaro M, Rosenthal N, Nervi C, Adamo S
Molecular biology of the cell 2005 Aug;16(8):3632-41
Molecular biology of the cell 2005 Aug;16(8):3632-41
Blockade of nuclear factor of activated T cells activation signaling suppresses balloon injury-induced neointima formation in a rat carotid artery model.
Liu Z, Zhang C, Dronadula N, Li Q, Rao GN
The Journal of biological chemistry 2005 Apr 15;280(15):14700-8
The Journal of biological chemistry 2005 Apr 15;280(15):14700-8
Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis.
Minami T, Horiuchi K, Miura M, Abid MR, Takabe W, Noguchi N, Kohro T, Ge X, Aburatani H, Hamakubo T, Kodama T, Aird WC
The Journal of biological chemistry 2004 Nov 26;279(48):50537-54
The Journal of biological chemistry 2004 Nov 26;279(48):50537-54
Interleukin (IL)-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms.
Barlic J, McDermott DH, Merrell MN, Gonzales J, Via LE, Murphy PM
The Journal of biological chemistry 2004 Nov 19;279(47):48520-34
The Journal of biological chemistry 2004 Nov 19;279(47):48520-34
IL-4-induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation.
Seki N, Miyazaki M, Suzuki W, Hayashi K, Arima K, Myburgh E, Izuhara K, Brombacher F, Kubo M
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):6158-66
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):6158-66
NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching.
McCullagh KJ, Calabria E, Pallafacchina G, Ciciliot S, Serrano AL, Argentini C, Kalhovde JM, Lømo T, Schiaffino S
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 20;101(29):10590-5
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 20;101(29):10590-5
Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells.
Kerstan A, Hünig T
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1341-5
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1341-5
Role of NFAT proteins in IL13 gene transcription in mast cells.
Monticelli S, Solymar DC, Rao A
The Journal of biological chemistry 2004 Aug 27;279(35):36210-8
The Journal of biological chemistry 2004 Aug 27;279(35):36210-8
Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production.
Cannon JL, Burkhardt JK
Journal of immunology (Baltimore, Md. : 1950) 2004 Aug 1;173(3):1658-62
Journal of immunology (Baltimore, Md. : 1950) 2004 Aug 1;173(3):1658-62
Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kappa B proteins.
Patra AK, Na SY, Bommhardt U
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 15;172(8):4812-20
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 15;172(8):4812-20
Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells.
Pfeifhofer C, Kofler K, Gruber T, Tabrizi NG, Lutz C, Maly K, Leitges M, Baier G
The Journal of experimental medicine 2003 Jun 2;197(11):1525-35
The Journal of experimental medicine 2003 Jun 2;197(11):1525-35
The basis for TCR-mediated regulation of the IL-2 receptor alpha chain gene: role of widely separated regulatory elements.
Kim HP, Leonard WJ
The EMBO journal 2002 Jun 17;21(12):3051-9
The EMBO journal 2002 Jun 17;21(12):3051-9
Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation.
Diehl S, Chow CW, Weiss L, Palmetshofer A, Twardzik T, Rounds L, Serfling E, Davis RJ, Anguita J, Rincón M
The Journal of experimental medicine 2002 Jul 1;196(1):39-49
The Journal of experimental medicine 2002 Jul 1;196(1):39-49
Cannabinol enhancement of interleukin-2 (IL-2) expression by T cells is associated with an increase in IL-2 distal nuclear factor of activated T cell activity.
Jan TR, Rao GK, Kaminski NE
Molecular pharmacology 2002 Feb;61(2):446-54
Molecular pharmacology 2002 Feb;61(2):446-54
The calcineurin-NFAT pathway and muscle fiber-type gene expression.
Swoap SJ, Hunter RB, Stevenson EJ, Felton HM, Kansagra NV, Lang JM, Esser KA, Kandarian SC
American journal of physiology. Cell physiology 2000 Oct;279(4):C915-24
American journal of physiology. Cell physiology 2000 Oct;279(4):C915-24
Expression of NFAT-family proteins in normal human T cells.
Lyakh L, Ghosh P, Rice NR
Molecular and cellular biology 1997 May;17(5):2475-84
Molecular and cellular biology 1997 May;17(5):2475-84
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells.
Latinis KM, Norian LA, Eliason SL, Koretzky GA
The Journal of biological chemistry 1997 Dec 12;272(50):31427-34
The Journal of biological chemistry 1997 Dec 12;272(50):31427-34
NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity.
Ho SN, Thomas DJ, Timmerman LA, Li X, Francke U, Crabtree GR
The Journal of biological chemistry 1995 Aug 25;270(34):19898-907
The Journal of biological chemistry 1995 Aug 25;270(34):19898-907
No comments: Submit comment
No validations: Submit validation data