FNab09997

antibody from FineTest Biotech

Targeting: CDC20 CDC20A, p55CDC

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Immunohistochemistry

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Validation data

Product number: FNab09997 - Provider product page
Provider: FineTest Biotech
Product name: Cdc20 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome(APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: cell division cycle 20 homolog
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CDC20 protein structure - FNab09997 shown in red.