28770-1-AP

antibody from Proteintech Group

Targeting: KAT2B GCN5, GCN5L, P/CAF, PCAF

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

28770-1-AP

Provider

Proteintech Group

Product name

PCAF antibody

Antibody type

Polyclonal

Description

PCAF antibody (Cat. #28770-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: WB, ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation.

Li W, Han J, Huang B, Xu T, Wan Y, Luo D, Kong W, Yu Y, Zhang L, Nian Y, Chu B, Yin C
The EMBO journal 2025 Mar;44(6):1641-1662

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P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis.

Yang WD, Zhang ZH, Zhao MY, Shao K, Ma YF, Shen Q, Lu MR, Shao ZY, Xu JY, Cao MH, Meng S, Chu SF, Yong HM, Ding J, Bai J
Communications biology 2025 Jul 7;8(1):1016

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Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.

Liu M, Xie WJ, Zhang X, Wu W, Li G, Wang L
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31

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Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription.

Pei L, Zhu Y, Li W, Xu B, Sun J
Molecular medicine (Cambridge, Mass.) 2025 Feb 3;31(1):39

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MRPL12 K163 acetylation inhibits ccRCC via driving mitochondrial metabolic reprogramming.

Ji X, Xue F, Wang Y, Gao D, Sun J, Dong T, Mu Q, Xu Q, Sun S, Liu Y, Wan Q
Cell death & disease 2025 Aug 26;16(1):646

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SIRT2-mediated deacetylation of ACLY promotes the progression of oesophageal squamous cell carcinoma.

Zhang X, Xu Y, Li S, Qin Y, Zhu G, Zhang Q, Zhang Y, Guan F, Fan T, Liu H
Journal of cellular and molecular medicine 2024 Mar;28(6):e18129

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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite.

Li Y, Huang M, Wang M, Wang Y, Deng P, Li C, Huang J, Chen H, Wei Z, Ouyang Q, Zhao J, Lu Y, Su S
Cancer cell 2024 Jun 10;42(6):985-1002.e18

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Integrative Analysis of Lactylome and Proteome of Hypertrophic Scar To Identify Pathways or Proteins Associated with Disease Development.

Zhang E, Yan Q, Sun Y, Li J, Chen L, Zou J, Zeng S, Jiang J, Li J
Journal of proteome research 2024 Aug 2;23(8):3367-3382

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The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling.

Ma W, Zhang J, Chen W, Liu N, Wu T
Journal of experimental & clinical cancer research : CR 2024 Apr 19;43(1):117