PLD1

This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]

Description

phospholipase D1

Protein family

Disease related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Protein evidence (Peptideatlas), RAS pathway related proteins

Chromosome

3:q26.31 (171600404 - 171810950)

Ensembl ID

ENSG00000075651  (ver. 99.38)

Orthologs

Mouse Pld1: ENSMUSG00000027695

UniProt

Q13393

neXtProt

NX_Q13393

Human splice variants
Mouse splice variants