PLD1

This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]

Description

phospholipase D1

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014), RAS pathway related proteins

Chromosome

3:q26.31 (171600405 - 171810950)

Ensembl ID

ENSG00000075651  (ver. 84.38)

Orthologs

Mouse Pld1: ENSMUSG00000027695

UniProt

Q13393

neXtProt

NX_Q13393

Human splice variants
Mouse splice variants