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- Antibody Data
- Antigen structure
- References [10]
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- Product number
- ABIN350745 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350745, RRID:AB_10782313
- Product name
- anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (4th Cytoplasmic Loop) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the 4th cytoplasmic loop of human Polycystic kidney disease 2 protein (PKD2, Polycystin-2, Polycystwin) conjugated to an immunogenic carrier protein was used as the antigen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- 4th Cytoplasmic Loop
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Polycystin channels and kidney disease.
In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.
Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations.
Seven novel mutations of the PKD2 gene in families with autosomal dominant polycystic kidney disease.
A spectrum of mutations in the second gene for autosomal dominant polycystic kidney disease (PKD2).
Characterization of the exon structure of the polycystic kidney disease 2 gene (PKD2).
A gene similar to PKD1 maps to chromosome 4q22: a candidate gene for PKD2.
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein.
Molina H, Horn DM, Tang N, Mathivanan S, Pandey A
Proceedings of the National Academy of Sciences of the United States of America 2007 Feb 13;104(7):2199-204
Proceedings of the National Academy of Sciences of the United States of America 2007 Feb 13;104(7):2199-204
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell 2006 Nov 3;127(3):635-48
Cell 2006 Nov 3;127(3):635-48
Polycystin channels and kidney disease.
Stayner C, Zhou J
Trends in pharmacological sciences 2001 Nov;22(11):543-6
Trends in pharmacological sciences 2001 Nov;22(11):543-6
In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.
Lehtonen S, Ora A, Olkkonen VM, Geng L, Zerial M, Somlo S, Lehtonen E
The Journal of biological chemistry 2000 Oct 20;275(42):32888-93
The Journal of biological chemistry 2000 Oct 20;275(42):32888-93
Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations.
Watnick T, He N, Wang K, Liang Y, Parfrey P, Hefferton D, St George-Hyslop P, Germino G, Pei Y
Nature genetics 2000 Jun;25(2):143-4
Nature genetics 2000 Jun;25(2):143-4
Seven novel mutations of the PKD2 gene in families with autosomal dominant polycystic kidney disease.
Torra R, Viribay M, Tellería D, Badenas C, Watson M, Harris P, Darnell A, San Millán JL
Kidney international 1999 Jul;56(1):28-33
Kidney international 1999 Jul;56(1):28-33
A spectrum of mutations in the second gene for autosomal dominant polycystic kidney disease (PKD2).
Veldhuisen B, Saris JJ, de Haij S, Hayashi T, Reynolds DM, Mochizuki T, Elles R, Fossdal R, Bogdanova N, van Dijk MA, Coto E, Ravine D, Nørby S, Verellen-Dumoulin C, Breuning MH, Somlo S, Peters DJ
American journal of human genetics 1997 Sep;61(3):547-55
American journal of human genetics 1997 Sep;61(3):547-55
Characterization of the exon structure of the polycystic kidney disease 2 gene (PKD2).
Hayashi T, Mochizuki T, Reynolds DM, Wu G, Cai Y, Somlo S
Genomics 1997 Aug 15;44(1):131-6
Genomics 1997 Aug 15;44(1):131-6
A gene similar to PKD1 maps to chromosome 4q22: a candidate gene for PKD2.
Schneider MC, Rodriguez AM, Nomura H, Zhou J, Morton CC, Reeders ST, Weremowicz S
Genomics 1996 Nov 15;38(1):1-4
Genomics 1996 Nov 15;38(1):1-4
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein.
Mochizuki T, Wu G, Hayashi T, Xenophontos SL, Veldhuisen B, Saris JJ, Reynolds DM, Cai Y, Gabow PA, Pierides A, Kimberling WJ, Breuning MH, Deltas CC, Peters DJ, Somlo S
Science (New York, N.Y.) 1996 May 31;272(5266):1339-42
Science (New York, N.Y.) 1996 May 31;272(5266):1339-42
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