67070-1-Ig

antibody from Proteintech Group

Targeting: PPP1CA PP-1A, PP1A, PP1alpha, PPP1A

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

67070-1-Ig

Provider

Proteintech Group

Product name

PPP1CA antibody

Antibody type

Monoclonal

Description

PPP1CA antibody (Cat. #67070-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1C10A2

Vial size

20ul, 150ul

References

Submitted references

Excessive mitochondrial stress response triggers neuronal injury through the persistent eIF2α phosphorylation in mice exposed to manganese.

Jia Y, He B, Chen K, Liu K, Yu C, Sun B, Ma Z, Xu B
Journal of hazardous materials 2025 Sep 15;496:139407

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PPP1CA promotes hepatocellular carcinoma progression in a YAP1-dependent way.

Liu X, Xu G, Luo W, Wang K, Wang F
Cellular signalling 2025 Oct;134:111938

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PP1A Modulates the Efficacy of Lenvatinib Plus ICIs Therapy by Inhibiting Ferroptosis in Hepatocellular Carcinoma.

Zhou J, Gao M, Zhang S, Guo WW, He W, Zhang M, Chen X, Dongzhi C, Li X, Yuan Y, Ma W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(27):e2501730

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IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth.

Zhou B, Zhao Q, Hou G, He J, Sha N, Zheng K, Peng H, Wang W, Zhou Y, Chen T, Jiang Y
Cell reports 2025 Jan 28;44(1):115116

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Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice.

Yin W, Xu H, Bai Z, Wu Y, Zhang Y, Liu R, Wang Z, Zhang B, Shen J, Zhang H, Chen X, Ma D, Shi X, Yan L, Zhang C, Jiang H, Chen K, Guo D, Niu W, Yin H, Zhang WJ, Luo C, Xie X
Nature communications 2025 Jan 11;16(1):598

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Isoliensinine promotes vasorelaxation and inhibits constriction by regulating the calcium channel in hypertension: In vitro and in vivo approaches.

Wu M, Zhou Y, Guo Z, Lian D, Chen H, Li R, Lin J, Ali F, Shen A, Peng J
European journal of pharmacology 2025 Aug 15;1001:177765

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The NS2B-PP1α-eIF2α axis: Inhibiting stress granule formation and Boosting Zika virus replication.

Wu X, Zhang L, Liu C, Cheng Q, Zhao W, Chen P, Qin Y, Chen M
PLoS pathogens 2024 Jun;20(6):e1012355

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Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.

Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150

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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy.

Hu C, Shen L, Zou F, Wu Y, Wang B, Wang A, Wu C, Wang L, Liu J, Wang W, Liu Q
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3694-3707

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EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1, TRF2, and RAD50.

Li KQ, Liu GJ, Liu XY, Chen QF, Huang XY, Tu Q, Zhang J, Chang Q, Xie YH, Hua R, Xu DM, Liu Z, Zhao B
Zoological research 2023 May 18;44(3):636-649

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CREB Inactivation by HDAC1/PP1γ Contributes to Dopaminergic Neurodegeneration in Parkinson's Disease.

Xu X, He X, Zhang Z, Chen Y, Li J, Ma S, Huang Q, Li M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Jun 1;42(22):4594-4604

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Nuclear accumulation of histone deacetylase 4 (HDAC4) by PP1-mediated dephosphorylation exerts neurotoxicity in Pb-exposed neural cells.

Gu X, Huang X, Li D, Bi N, Yu X, Wang HL
Neurotoxicology 2020 Dec;81:395-405

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Small interfering RNA-mediated knockdown of KRT80 suppresses colorectal cancer proliferation.

Lin J, Fan X, Chen J, Xie X, Yu H
Experimental and therapeutic medicine 2020 Dec;20(6):176