BS5895

antibody from Bioworld Technology, Inc

Targeting: RGS10

Immunohistochemistry

Antibody data

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Validation data

Product number: BS5895 - Provider product page
Provider: Bioworld Technology, Inc
Product name: RGS10 polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 357-402 of Human RGS10.
Description: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein Ï«, ÉÇ and ÎÛ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Ï« subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four GÏ« GTPase-activating proteins (GAPs) have been identified and are designated RGS1 (regulator of G protein signaling), RGS4, RGS10 and GAIP (GÏ«-interacting protein). Each of these proteins has been shown to deactivate specific GÏ« isoforms by increasing the rate at which they convert GTP to GDP. RGS1, RGS4 and GAIP bind tightly to and exhibit GAP activity towards GÏ« i, GÏ« o and GÏ« t, but not GÏ« s. RGS10 increases the GTP hydrolytic activity of several members of the GÏ« i sub-family, including GÏ« i-3, GÏ« z and GÏ« o.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

RGS10 protein structure - BS5895 shown in red.