26582-1-AP

antibody from Proteintech Group

Targeting: KITLG DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF

Provider product page for 26582-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [21]
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Product number: 26582-1-AP - Provider product page
Provider: Proteintech Group
Product name: SCF antibody
Antibody type: Polyclonal
Description: KD/KO validated SCF antibody (Cat. #26582-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

KITLG protein structure - 26582-1-AP shown in red.

Submitted references Zhi Chuan Ling oral liquid alleviates Th2-type asthma via IL-4-JAK1-STAT6 and KIT signaling pathways.

Yang J, Zhou X, Weng DZ, Wang H, Jin Z, Han JY, Liu J, Feng C
Journal of ethnopharmacology 2026 May 23;363:121408

Effects of Arvcf on anxiety- and depression-like behaviors in mice of different ages and sexes.

Li H, Zhao Y, Zhang M, Zhao P, Zhang B, Li B, Yang Z, Li MD
Journal of affective disorders 2026 Aug 15;407:121790

Changrun Formula Relieves Functional Constipation by Improving Intestinal Motility in Rats.

Xiao Q, Hong Y, Geng X
Gastroenterology research and practice 2025;2025:5790162

Olive Oil Solution of Volatile Oil from Citri Reticulatae Pericarpium Viride Alleviates Slow-Transit Constipation via Regulating SCF/c-Kit Signaling Pathway and Intestinal Flora.

Zou S, Xie B, An Z, Li F, Cui L, Zhang Z, Bu W, He D
Drug design, development and therapy 2025;19:4275-4295

Wuzi-Yanzong-Wan inhibits testicular mitochondrial apoptosis in rats by downregulating TAp73-Mediated P38 MAPK-ADAM17 pathway.

Liu Z, Ni X, Li J, Pan M, Xu F, Zhao H, Li L, Wang T
Frontiers in pharmacology 2025;16:1665356

Macrophage-derived amphiregulin induces myofibroblast transition in adipogenic lineage precursors near Staphylococcus aureus abscess in bone marrow.

Yang B, Su J, Wu J, Wang Z, Hu J, Yang M, Lin Y, Jin M, Bai X, Yu B, Zhang X
Nature communications 2025 Sep 25;16(1):8409

DNA methylation of POU5F1 by DNMT1 and DNMT3B triggers apoptosis in interstitial Cajal-like cells via c-kit/SCF inhibition during cholesterol gallstone formation.

Liu Y, Fu B, He Q, Bai X, Fan Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167689

Study on the Mechanism and Dose-Effect Relationship of Flavonoids in Different Extracts of Radix Hedysari Against Gastrointestinal Injury Induced by Chemotherapy.

Zhao S, Yang M, Yang Z, He H, Wang Z, Zhu X, Cui Z, Shao J
Pharmaceuticals (Basel, Switzerland) 2025 Jul 20;18(7)

Unveiling Xuanshen decoction: A novel approach to combat slow transit constipation.

Zeng XL, Zhu LJ, Zhang Y, Yang XD, Zhu YJ
World journal of gastroenterology 2025 Aug 14;31(30):109187

Exploring the biological behavior and underlying mechanism of KITLG in triple-negative breast cancer.

Qin L, Li Y, Huang Y, Tang C, Yang W, Tang Y, Qiu C, Mao M, Li J
Journal of Cancer 2024;15(3):764-775

Prunus persica (L.) Batsch blossom soluble dietary fiber synergia polyphenol improving loperamide-induced constipation in mice via regulating stem cell factor/C-kit, NF-κB signaling pathway and gut microbiota.

Liang S, He Z, Liang Z, Wang K, Du B, Guo R, Li P
Food research international (Ottawa, Ont.) 2024 Sep;192:114761

Network pharmacology combined with experimental validation reveals the mechanism of action of erpixing granules on functional dyspepsia.

Bai Y, Liu F, Wan Y, Wu X, Luo S, Zhang L, Tang H, Li T, Tang X, Qin W, Gan W, Yang Y, Yin Z, Xie Y, Guo P
Journal of ethnopharmacology 2024 Nov 15;334:118553

Qi Lang formula relieves constipation via targeting SCF/c-kit signaling pathway: An integrated study of network pharmacology and experimental validation.

Li J, Fu Y, Wang Y, Zheng Y, Zhang K, Li Y
Heliyon 2024 Jun 15;10(11):e31860

Improvement of functional dyspepsia with Suaeda salsa (L.) Pall via regulating brain-gut peptide and gut microbiota structure.

Zhang W, Wang X, Yin S, Wang Y, Li Y, Ding Y
European journal of nutrition 2024 Aug;63(5):1929-1944

Arctiin alleviates functional constipation by enhancing intestinal motility in mice.

Wang Y, Jiang H, Wang L, Gan H, Xiao X, Huang L, Li W, Li Z
Experimental and therapeutic medicine 2023 May;25(5):199

Increased Chymase-Positive Mast Cells in High-Grade Mucoepidermoid Carcinoma of the Parotid Gland.

Nishimura H, Jin D, Kinoshita I, Taniuchi M, Higashino M, Terada T, Takai S, Kawata R
International journal of molecular sciences 2023 May 5;24(9)

Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.

Kim M, Kruhlak M, Hoffmann V, Zerfas P, Bishop K, Doolittle WKL, Edmondson EF, Zhu YJ, Cheng SY
Thyroid : official journal of the American Thyroid Association 2023 Feb;33(2):239-250

miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.

Hong Y, Ren X, Liu W, Sun K, Chen B, Liu B, Yu X, Chen Q, Qian Q, Xie X, Jiang C
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G436-G447

Increase in Chymase-Positive Mast Cells in Recurrent Pleomorphic Adenoma and Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland.

Kinoshita I, Jin D, Higashino M, Terada T, Kurisu Y, Takai S, Kawata R
International journal of molecular sciences 2021 Nov 23;22(23)

Shengxuening Extracted from Silkworm Excrement Mitigates Myelosuppression via SCF-Mediated JAK2/STAT3 Signaling.

Ding L, Tan Y, Xu L, Jin Y, Liu Y, Tu H, Zhang D, Wu B, Chen Y, Shen H, Liu L, Huang T, Zhou F
Chemistry & biodiversity 2021 Jun;18(6):e2100139

High expression of KITLG is a new hallmark activating the MAPK pathway in type A and AB thymoma.

Yang Z, Liu S, Wang Y, Chen Y, Zhang P, Liu Y, Zhang H, Zhang P, Tao Z, Xiong K
Thoracic cancer 2020 Jul;11(7):1944-1954

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