MAB3647

antibody from Abnova Corporation

Targeting: LCP2 SLP-76, SLP76

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

MAB3647

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB3647, RRID:AB_10551755

Product name

LCP2 monoclonal antibody, clone SLP-76/03

Antibody type

Monoclonal

Antigen

Recombinant His fusion protein corresponding to amino acids 216-434 of human LCP2.

Reactivity

Human, Mouse, Porcine

Host

Mouse

Isotype

IgG

Vial size

100 µg

Storage

Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Dual role of SLP-76 in mediating T cell receptor-induced activation of phospholipase C-gamma1.

Beach D, Gonen R, Bogin Y, Reischl IG, Yablonski D
The Journal of biological chemistry 2007 Feb 2;282(5):2937-46

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SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK.

Bogin Y, Ainey C, Beach D, Yablonski D
Proceedings of the National Academy of Sciences of the United States of America 2007 Apr 17;104(16):6638-43

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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond.

Koretzky GA, Abtahian F, Silverman MA
Nature reviews. Immunology 2006 Jan;6(1):67-78

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western Blotting analysis (reducing conditions) of whole cell lysate using LCP2 monoclonal antibody, clone SLP-76/03 (Cat # MAB3647).Lane 1 : HPB-ALL (human peripheral blood T cell leukemia cell line).Lane 2 : Jurkat (human peripheral blood T cell leukemia cell line).Lane 3 : RAMOS (human Burkitt lymphoma cell line).

Validation comment

Western Blot (Cell lysate)