Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 15468-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15468-1-AP, RRID:AB_2209035
- Product name
- TRADD antibody
- Antibody type
- Polyclonal
- Description
- TRADD antibody (Cat. #15468-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Caspase-8 drove apoptosis of BMECs to promote neutrophil infiltration and DE205B clearance in meningitis.
Ampelopsis grossedentata protects against ethanol-induced acute duodenal injury by inhibiting TNF-triggered caspases-dependent apoptosis in mice.
Centipede Polypeptide Affects the Inflammatory Reaction and Ferroptosis of Liver Cancer Cells Through the p53/TRAIL Pathway.
PeiTuQingXin formula alleviated atopic dermatitis symptoms via inhibiting TRADD/TRAF2/RIP1 complex mediated NF-κB signaling pathway activation.
Modified Jiaoqi Powder enhances epithelial autophagy against TNF-triggered apoptosis in chronic ulcerative colitis.
Classical prescription Daqinjiao decoction inhibit cerebral ischemia/reperfusion induced necroptosis and ferroptosis through multiple mechanisms.
TNFAIP3-interacting protein 1 (ABIN-1) negatively regulates caspase-8/FADD-dependent pyroptosis.
Dingxian pill alleviates hippocampal neuronal apoptosis in epileptic mice through TNF-α/TNFR1 signaling pathway inhibition.
tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.
TRAF2 inhibits senescence in hepatocellular carcinoma cells via regulating the ROMO1/ NAD(+)/SIRT3/SOD2 axis.
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8.
Knockdown of circROBO2 attenuates acute myocardial infarction through regulating the miR-1184/TRADD axis.
Wang X, Lin W, Ye L, Chen X, Ren J, Xue F, Dai J, Tang F
Microbiological research 2025 Sep;298:128223
Microbiological research 2025 Sep;298:128223
Ampelopsis grossedentata protects against ethanol-induced acute duodenal injury by inhibiting TNF-triggered caspases-dependent apoptosis in mice.
Sun CY, Li WQ, Lu JW, Zhang AY, Chu QX, Tang L, Gao W, Cai JJ, Lu Y, Liu D
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120462
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120462
Centipede Polypeptide Affects the Inflammatory Reaction and Ferroptosis of Liver Cancer Cells Through the p53/TRAIL Pathway.
Xing X, Lu L, Huang Z, Wang J, Wang L, Hu Y, Yin S, Tian S
Journal of cellular and molecular medicine 2025 Oct;29(19):e70844
Journal of cellular and molecular medicine 2025 Oct;29(19):e70844
PeiTuQingXin formula alleviated atopic dermatitis symptoms via inhibiting TRADD/TRAF2/RIP1 complex mediated NF-κB signaling pathway activation.
Cheng Z, Ma X, Luo F, Mo X, Liu J, Chen D, Yan F
Archives of dermatological research 2025 Mar 8;317(1):535
Archives of dermatological research 2025 Mar 8;317(1):535
Modified Jiaoqi Powder enhances epithelial autophagy against TNF-triggered apoptosis in chronic ulcerative colitis.
Liu W, Yan X, An J, Wang X, Mi H, Liu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:155996
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:155996
Classical prescription Daqinjiao decoction inhibit cerebral ischemia/reperfusion induced necroptosis and ferroptosis through multiple mechanisms.
Liu Y, Liu J, Hu N, Li Z, Liu A, Luo R, Du S, Guo D, Li J, Duan J
Journal of ethnopharmacology 2025 Jan 31;340:119300
Journal of ethnopharmacology 2025 Jan 31;340:119300
TNFAIP3-interacting protein 1 (ABIN-1) negatively regulates caspase-8/FADD-dependent pyroptosis.
Li X, Wang D, Su Z, Mao X
The FEBS journal 2025 Apr;292(8):1972-1990
The FEBS journal 2025 Apr;292(8):1972-1990
Dingxian pill alleviates hippocampal neuronal apoptosis in epileptic mice through TNF-α/TNFR1 signaling pathway inhibition.
Wang Q, Qin B, Yu H, Yu H, Zhang X, Li M, Zhou Y, Diao L, Liu H
Journal of ethnopharmacology 2024 Nov 15;334:118579
Journal of ethnopharmacology 2024 Nov 15;334:118579
tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.
Mo D, Tang X, Ma Y, Chen D, Xu W, Jiang N, Zheng J, Yan F
Journal of translational medicine 2024 Jul 30;22(1):706
Journal of translational medicine 2024 Jul 30;22(1):706
TRAF2 inhibits senescence in hepatocellular carcinoma cells via regulating the ROMO1/ NAD(+)/SIRT3/SOD2 axis.
Yao J, Liang X, Xu S, Liu Y, Shui L, Li S, Guo H, Xiao Z, Zhao Y, Zheng M
Free radical biology & medicine 2024 Feb 1;211:47-62
Free radical biology & medicine 2024 Feb 1;211:47-62
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
Dong L, Jiang H, Chen K, Xie J, An Q, Deng F, Sun Z, Liu Y, Zhou J, Zhang L, Lu X, Wang M, Chen Z, Zou X, Zuo D
International journal of biological sciences 2022;18(4):1580-1593
International journal of biological sciences 2022;18(4):1580-1593
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
Fan XZ, Wang YY, Cui ZY, Cheng ZH, Zhang HL, Gamper N, Zhang F, Han M
Free radical biology & medicine 2022 Jan;178:111-124
Free radical biology & medicine 2022 Jan;178:111-124
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8.
Zhang JY, Zhou B, Sun RY, Ai YL, Cheng K, Li FN, Wang BR, Liu FJ, Jiang ZH, Wang WJ, Zhou D, Chen HZ, Wu Q
Cell research 2021 Sep;31(9):980-997
Cell research 2021 Sep;31(9):980-997
Knockdown of circROBO2 attenuates acute myocardial infarction through regulating the miR-1184/TRADD axis.
Chen TP, Zhang NJ, Wang HJ, Hu SG, Geng X
Molecular medicine (Cambridge, Mass.) 2021 Mar 3;27(1):21
Molecular medicine (Cambridge, Mass.) 2021 Mar 3;27(1):21
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The TRADD antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRADD. This antibody recognizes human, mouse, rat antigen. The TRADD antibody has been validated for the following applications: ELISA, WB analysis.