FNab08915

antibody from FineTest Biotech
Targeting: TRADD Hs.89862
Provider product page for FNab08915
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab08915 - Provider product page
Provider
FineTest Biotech
Product name
TRADD antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A(By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Reactivity
Human, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
TNFRSF1A-associated via death domai
n
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
TRADD protein structure - FNab08915 shown in red.