Antibody data
- Antibody Data
- Antigen structure
- References [38]
- Comments [0]
- Validations [0]
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- Product number
- 66320-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- Gamma Tubulin antibody
- Antibody type
- Monoclonal
- Description
- Gamma Tubulin antibody (Cat. #66320-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, Canine, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Canine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3F9H8
- Vial size
- 150ul
Submitted references Use of Small-Molecule Inhibitors of CILK1 and AURKA as Cilia-Promoting Drugs to Decelerate Medulloblastoma Cell Replication.
CETN3 deficiency induces microcephaly by disrupting neural stem/progenitor cell fate through impaired centrosome assembly and RNA splicing.
Human disease variants of KATNIP fail to support CILK1 activation and control of primary cilia.
Inactivation of the Catalytic Activity of Mps1 Kinase Prevents Its Own Degradation at Centrosomes.
Partial TEX14 peptides inhibit proliferation of cancer cells and have potential as anti-tumour agents.
Proteomic profiling of primary cilia in the developing brain uncovers new regulators of cortical development.
Competitive antagonism of KAT7 crotonylation against acetylation affects procentriole formation and colorectal tumorigenesis.
Proximity based proteomics reveals Git1 as a regulator of Smoothened signaling.
Growth hormone regulates the stem cell population in the growth plate.
KIFC1 depends on TRIM37-mediated ubiquitination of PLK4 to promote centrosome amplification in endometrial cancer.
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.
Naringin Induces ROS-Stimulated G(1) Cell-Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma Cells.
An epilepsy-associated CILK1 variant compromises KATNIP regulation and impairs primary cilia and Hedgehog signaling.
An Epilepsy-Associated CILK1 Variant Compromises KATNIP Regulation and Impairs Primary Cilia and Hedgehog Signaling.
S100A8 knockdown activates the PI3K/AKT signaling pathway to inhibit microglial autophagy and improve cognitive impairment mediated by chronic sleep deprivation.
Human CYP1A1-activated aneugenicity of aflatoxin B1 in mammalian cells and its combined effect with benzo(a)pyrene.
The Scaffold Protein KATNIP Enhances CILK1 Control of Primary Cilia.
Characterization of Primary Cilia Formation in Human ESC-Derived Retinal Organoids.
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization.
CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis.
MYO10 regulates genome stability and cancer inflammation through mediating mitosis.
TSNAXIP1 is required for sperm head formation and male fertility.
Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4.
The phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation.
A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder.
CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma.
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
The phytochemical, corynoline, diminishes Aurora kinase B activity to induce mitotic defect and polyploidy.
Modulation of Primary Cilia by Alvocidib Inhibition of CILK1.
GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca(2+) nanoparticles underlies distinct gene therapy effect in ovarian cancer.
Distribution of prototypical primary cilia markers in subtypes of retinal ganglion cells.
Polycaprolactone Electrospun Scaffolds Produce an Enrichment of Lung Cancer Stem Cells in Sensitive and Resistant EGFRm Lung Adenocarcinoma.
Time-resolved proteomics profiling of the ciliary Hedgehog response.
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production.
Prohibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells.
Fu SH, Park C, Shah NA, Limerick A, Powers EW, Mann CB, Hyun EM, Zhang Y, Brautigan DL, Hao S, Abounader R, Fu Z
Biomedicines 2026 Jan 24;14(2)
Biomedicines 2026 Jan 24;14(2)
CETN3 deficiency induces microcephaly by disrupting neural stem/progenitor cell fate through impaired centrosome assembly and RNA splicing.
Xu J, Mao X, Liu Z, Jiang N, Wong XE, Liu D, Wang Y, Zhan H, Liu S, Yu J, Yuan R, Bai Q, Bai X, Huang W, Xie R, Krenn V, Kirchhoff F, Wang H, Guo Z, Bian S
EMBO molecular medicine 2025 Oct;17(10):2735-2761
EMBO molecular medicine 2025 Oct;17(10):2735-2761
Human disease variants of KATNIP fail to support CILK1 activation and control of primary cilia.
Carpenter EH, Chu CY, Limerick A, Brautigan DL, Fu Z
Journal of cell science 2025 Oct 15;138(20)
Journal of cell science 2025 Oct 15;138(20)
Inactivation of the Catalytic Activity of Mps1 Kinase Prevents Its Own Degradation at Centrosomes.
Halder S, Dutta A, Mondal R, Chowdhury B, Das BB, Majumder S
Cytoskeleton (Hoboken, N.J.) 2025 Nov;82(11):764-772
Cytoskeleton (Hoboken, N.J.) 2025 Nov;82(11):764-772
Partial TEX14 peptides inhibit proliferation of cancer cells and have potential as anti-tumour agents.
Iwamori T, Sakurai Y, Sultana T, Katakura Y, Iwamori N
Human cell 2025 Nov 11;39(1):6
Human cell 2025 Nov 11;39(1):6
Proteomic profiling of primary cilia in the developing brain uncovers new regulators of cortical development.
Liu X, Gutierrez OT, Kaur G, Al-Issa Y, Baboo S, Diedrich JK, Cai E, Yates JR 3rd, Ge X
bioRxiv : the preprint server for biology 2025 May 4;
bioRxiv : the preprint server for biology 2025 May 4;
Competitive antagonism of KAT7 crotonylation against acetylation affects procentriole formation and colorectal tumorigenesis.
Wang M, Mu G, Qiu B, Wang S, Tao C, Mao Y, Zhao X, Liu J, Chen K, Li Z, Wang W, Yang E, Yang Y
Nature communications 2025 Mar 10;16(1):2379
Nature communications 2025 Mar 10;16(1):2379
Proximity based proteomics reveals Git1 as a regulator of Smoothened signaling.
Zhang J, Kaur G, Cai E, Gutierrez OT, Liu X, Baboo S, Diedrich JK, Zhu JF, Myers BR, Yates JR 3rd, Ge X
bioRxiv : the preprint server for biology 2025 Jan 7;
bioRxiv : the preprint server for biology 2025 Jan 7;
Growth hormone regulates the stem cell population in the growth plate.
Chu NTL, Zhou B, Heinonen JO, Dregval O, Liu X, Trompet D, Tian X, Newton PT, Sävendahl L, Bendre A, Nilsson O, Ohlsson C, Chagin AS
Proceedings of the National Academy of Sciences of the United States of America 2025 Dec 2;122(48):e2512316122
Proceedings of the National Academy of Sciences of the United States of America 2025 Dec 2;122(48):e2512316122
KIFC1 depends on TRIM37-mediated ubiquitination of PLK4 to promote centrosome amplification in endometrial cancer.
Zhou K, He Y, Lin X, Zhou H, Xu X, Xu J
Cell death discovery 2024 Sep 30;10(1):419
Cell death discovery 2024 Sep 30;10(1):419
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.
Iannotta L, Fasiczka R, Favetta G, Zhao Y, Giusto E, Dall'Ara E, Wei J, Ho FY, Ciriani C, Cogo S, Tessari I, Iaccarino C, Liberelle M, Bubacco L, Taymans JM, Manzoni C, Kortholt A, Civiero L, Hilfiker S, Lu ML, Greggio E
Cell death & disease 2024 Oct 17;15(10):752
Cell death & disease 2024 Oct 17;15(10):752
Naringin Induces ROS-Stimulated G(1) Cell-Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma Cells.
Chen CH, Tien N, Yao CH, Chen SJ, Bau DT, Pandey S, Yang HL, Hseu YC, Chen SS, Lin ML
Environmental toxicology 2024 Nov;39(11):5059-5073
Environmental toxicology 2024 Nov;39(11):5059-5073
An epilepsy-associated CILK1 variant compromises KATNIP regulation and impairs primary cilia and Hedgehog signaling.
Limerick A, McCabe EA, Turner JS, Kuang KW, Brautigan DL, Hao Y, Chu C, Fu SH, Ahmadi S, Xu W, Fu Z
bioRxiv : the preprint server for biology 2024 May 17;
bioRxiv : the preprint server for biology 2024 May 17;
An Epilepsy-Associated CILK1 Variant Compromises KATNIP Regulation and Impairs Primary Cilia and Hedgehog Signaling.
Limerick A, McCabe EA, Turner JS, Kuang KW, Brautigan DL, Hao Y, Chu CY, Fu SH, Ahmadi S, Xu W, Fu Z
Cells 2024 Jul 26;13(15)
Cells 2024 Jul 26;13(15)
S100A8 knockdown activates the PI3K/AKT signaling pathway to inhibit microglial autophagy and improve cognitive impairment mediated by chronic sleep deprivation.
Xiong Y, Liang W, Wang X, Zhu H, Yi P, Wei G, Liu H, Lin Y, Zhang L, Ying J, Hua F
International immunopharmacology 2024 Dec 25;143(Pt 2):113375
International immunopharmacology 2024 Dec 25;143(Pt 2):113375
Human CYP1A1-activated aneugenicity of aflatoxin B1 in mammalian cells and its combined effect with benzo(a)pyrene.
Wang H, Fan Q, Liang Q, Wu Y, Ye Z, Wu H, Sun Q, Tang H, Liu Y, Liu Q, Chen Y
Chemico-biological interactions 2024 Apr 1;392:110923
Chemico-biological interactions 2024 Apr 1;392:110923
The Scaffold Protein KATNIP Enhances CILK1 Control of Primary Cilia.
Turner JS, McCabe EA, Kuang KW, Gailey CD, Brautigan DL, Limerick A, Wang EX, Fu Z
Molecular and cellular biology 2023;43(9):472-480
Molecular and cellular biology 2023;43(9):472-480
Characterization of Primary Cilia Formation in Human ESC-Derived Retinal Organoids.
Ning K, Luo Z, Kowal TJ, Tran M, Majumder R, Jarin TM, Wu AY, Goldberg JL, Sun Y
Stem cells international 2023;2023:6494486
Stem cells international 2023;2023:6494486
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization.
Qu K, Wang C, Huang L, Qin X, Zhang K, Qiu J, Wang G
APL bioengineering 2023 Sep;7(3):036104
APL bioengineering 2023 Sep;7(3):036104
CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis.
Wang B, Liang Z, Tan T, Zhang M, Jiang Y, Shang Y, Gao X, Song S, Wang R, Chen H, Liu J, Li J, Ren Y, Liu P
eLife 2023 Sep 22;12
eLife 2023 Sep 22;12
MYO10 regulates genome stability and cancer inflammation through mediating mitosis.
Mayca Pozo F, Geng X, Miyagi M, Amin AL, Huang AY, Zhang Y
Cell reports 2023 May 30;42(5):112531
Cell reports 2023 May 30;42(5):112531
TSNAXIP1 is required for sperm head formation and male fertility.
Sultana T, Iwamori T, Iwamori N
Reproductive medicine and biology 2023 Jan-Dec;22(1):e12520
Reproductive medicine and biology 2023 Jan-Dec;22(1):e12520
Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4.
Zhang C, Ma X, Wei G, Zhu X, Hu P, Chen X, Wang D, Li Y, Ruan T, Zhang W, Tao K, Wu C
iScience 2023 Jan 20;26(1):105745
iScience 2023 Jan 20;26(1):105745
The phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation.
Song C, Zhang Y, Li Y, Bie J, Wang Z, Yang X, Li H, Zhu L, Zhang T, Chang Q, Luo J
Cell death & disease 2023 Feb 9;14(2):98
Cell death & disease 2023 Feb 9;14(2):98
A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder.
Kuang H, Li Y, Wang Y, Shi M, Duan R, Xiao Q, She H, Liu Y, Liang Q, Teng Y, Zhou M, Liang D, Li Z, Wu L
Cell reports 2023 Dec 26;42(12):113445
Cell reports 2023 Dec 26;42(12):113445
CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma.
Liu Y, Liang W, Chang Y, He Z, Wu M, Zheng H, Ke X, Lv M, Liu Q, Liu Q, Tang W, Huang Q, Lu Y, He M, Yang Q, Mo C, Wang J, Peng K, Min Z, Su H, Chen J
Frontiers in immunology 2022;13:950884
Frontiers in immunology 2022;13:950884
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
Wei L, Ma W, Cai H, Peng SP, Tian HB, Wang JF, Gao L, He JP
Biomedical and environmental sciences : BES 2022 May 20;35(5):419-436
Biomedical and environmental sciences : BES 2022 May 20;35(5):419-436
The phytochemical, corynoline, diminishes Aurora kinase B activity to induce mitotic defect and polyploidy.
Yan Z, Shi Q, Liu X, Li J, Ahire V, Zhang S, Zhang J, Yang D, Allen TD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Mar;147:112645
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Mar;147:112645
Modulation of Primary Cilia by Alvocidib Inhibition of CILK1.
Wang EX, Turner JS, Brautigan DL, Fu Z
International journal of molecular sciences 2022 Jul 23;23(15)
International journal of molecular sciences 2022 Jul 23;23(15)
GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca(2+) nanoparticles underlies distinct gene therapy effect in ovarian cancer.
Su L, Sun Z, Qi F, Su H, Qian L, Li J, Zuo L, Huang J, Yu Z, Li J, Chen Z, Zhang S
Journal of nanobiotechnology 2022 Jul 20;20(1):340
Journal of nanobiotechnology 2022 Jul 20;20(1):340
Distribution of prototypical primary cilia markers in subtypes of retinal ganglion cells.
Kowal TJ, Dhande OS, Wang B, Wang Q, Ning K, Liu W, Berbari NF, Hu Y, Sun Y
The Journal of comparative neurology 2022 Aug;530(12):2176-2187
The Journal of comparative neurology 2022 Aug;530(12):2176-2187
Polycaprolactone Electrospun Scaffolds Produce an Enrichment of Lung Cancer Stem Cells in Sensitive and Resistant EGFRm Lung Adenocarcinoma.
Polonio-Alcalá E, Rabionet M, Ruiz-Martínez S, Palomeras S, Porta R, Vásquez-Dongo C, Bosch-Barrera J, Puig T, Ciurana J
Cancers 2021 Oct 22;13(21)
Cancers 2021 Oct 22;13(21)
Time-resolved proteomics profiling of the ciliary Hedgehog response.
May EA, Kalocsay M, D'Auriac IG, Schuster PS, Gygi SP, Nachury MV, Mick DU
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
Li J, Yan Z, Li H, Shi Q, Ahire V, Zhang S, Nimishetti N, Yang D, Allen TD, Zhang J
Journal of natural products 2021 Aug 27;84(8):2312-2320
Journal of natural products 2021 Aug 27;84(8):2312-2320
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.
Bosakova M, Abraham SP, Nita A, Hruba E, Buchtova M, Taylor SP, Duran I, Martin J, Svozilova K, Barta T, Varecha M, Balek L, Kohoutek J, Radaszkiewicz T, Pusapati GV, Bryja V, Rush ET, Thiffault I, Nickerson DA, Bamshad MJ, University of Washington Center for Mendelian Genomics, Rohatgi R, Cohn DH, Krakow D, Krejci P
EMBO molecular medicine 2020 Nov 6;12(11):e11739
EMBO molecular medicine 2020 Nov 6;12(11):e11739
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE
Nature 2020 Dec;588(7837):344-349
Nature 2020 Dec;588(7837):344-349
Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production.
Hu M, Schulze KE, Ghildyal R, Henstridge DC, Kolanowski JL, New EJ, Hong Y, Hsu AC, Hansbro PM, Wark PA, Bogoyevitch MA, Jans DA
eLife 2019 Jun 27;8
eLife 2019 Jun 27;8
Prohibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells.
Ma LL, Shen L, Tong GH, Tang N, Luo Y, Guo LL, Hu CT, Huang YX, Huang G, Jing FY, Liu C, Li ZY, Zhou N, Yan QW, Lei Y, Zhu SJ, Cheng ZQ, Cao GW, Deng YJ, Ding YQ
Oncotarget 2017 Sep 29;8(44):76340-76356
Oncotarget 2017 Sep 29;8(44):76340-76356
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