Explore
Validate
LearnHPA000612
antibody from Atlas Antibodies
Targeting: APOOL
AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA000612 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA000612, RRID:AB_1078594
- Product name
- Anti-APOOL
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human APOOL, Gene description: apolipoprotein O-like, Alternative Gene Names: AAIR8193, CXorf33, FAM121A, UNQ8193, Validated applications: ICC, IHC, WB, Uniprot ID: Q6UXV4, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
MIC26 and MIC27 are bona fide subunits of the MICOS complex in mitochondria and do not exist as glycosylated apolipoproteins
Colocalization for super-resolution microscopy via optimal transport.
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes.
Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner.
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10
Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells.
APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria.
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Systematically generated antibodies against human gene products: High throughput screening on sections from the rat nervous system
Damiecki M, Naha R, Schaumkessel Y, Westhoff P, Atanelov N, Stefanski A, Petzsch P, Stühler K, Köhrer K, Weber A, Anand R, Reichert A, Kondadi A
Life Science Alliance 2024;7(12):e202403038
Life Science Alliance 2024;7(12):e202403038
MIC26 and MIC27 are bona fide subunits of the MICOS complex in mitochondria and do not exist as glycosylated apolipoproteins
Ruzzenente B, Lubeck M, Derkum N, Naha R, Strohm R, Driessen M, Belgardt B, Roden M, Stühler K, Anand R, Reichert A, Kondadi A
PLOS ONE 2023;18(6):e0286756
PLOS ONE 2023;18(6):e0286756
Colocalization for super-resolution microscopy via optimal transport.
Tameling C, Stoldt S, Stephan T, Naas J, Jakobs S, Munk A
Nature computational science 2021 Mar;1:199-211
Nature computational science 2021 Mar;1:199-211
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
Narendra D, Sekine S, Poulton J, Springer D, Dombi E, Wu B, Shammas M, Nguyen D, Huang X, Liu Y
Human Molecular Genetics 2020;29(9):1547-1567
Human Molecular Genetics 2020;29(9):1547-1567
MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes.
Anand R, Kondadi AK, Meisterknecht J, Golombek M, Nortmann O, Riedel J, Peifer-Weiß L, Brocke-Ahmadinejad N, Schlütermann D, Stork B, Eichmann TO, Wittig I, Reichert AS
Life science alliance 2020 Oct;3(10)
Life science alliance 2020 Oct;3(10)
Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner.
Kondadi AK, Anand R, Hänsch S, Urbach J, Zobel T, Wolf DM, Segawa M, Liesa M, Shirihai OS, Weidtkamp-Peters S, Reichert AS
EMBO reports 2020 Mar 4;21(3):e49776
EMBO reports 2020 Mar 4;21(3):e49776
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10
Huang X, Wu B, Nguyen D, Liu Y, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra D
Human Molecular Genetics 2018
Human Molecular Genetics 2018
Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells.
Anand R, Strecker V, Urbach J, Wittig I, Reichert AS
PloS one 2016;11(8):e0160258
PloS one 2016;11(8):e0160258
APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria.
Weber TA, Koob S, Heide H, Wittig I, Head B, van der Bliek A, Brandt U, Mittelbronn M, Reichert AS
PloS one 2013;8(5):e63683
PloS one 2013;8(5):e63683
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Mulder J, Björling E, Jonasson K, Wernérus H, Hober S, Hökfelt T, Uhlén M
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
Systematically generated antibodies against human gene products: High throughput screening on sections from the rat nervous system
Mulder J, Wernérus H, Shi T, Pontén F, Hober S, Uhlén M, Hökfelt T
Neuroscience 2007;146(4):1689-1703
Neuroscience 2007;146(4):1689-1703
No comments: Submit comment
Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in Rh30 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-APOOL antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Sample type
- Human
- Protocol
- Protocol
