Explore
Validate
LearnHPA000612
antibody from Atlas Antibodies
Targeting: APOOL
AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193
Western blot
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA000612 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA000612, RRID:AB_1078594
- Product name
- Anti-APOOL
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human APOOL, Gene description: apolipoprotein O-like, Alternative Gene Names: AAIR8193, CXorf33, FAM121A, UNQ8193, Validated applications: ICC, IHC, WB, Uniprot ID: Q6UXV4, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
MIC26 and MIC27 are bona fide subunits of the MICOS complex in mitochondria and do not exist as glycosylated apolipoproteins
Colocalization for super-resolution microscopy via optimal transport
MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
Cristae undergo continuous cycles of membrane remodelling in a MICOS ‐dependent manner
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10
Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells
APOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria
Tissue Profiling of the Mammalian Central Nervous System Using Human Antibody-based Proteomics
Systematically generated antibodies against human gene products: High throughput screening on sections from the rat nervous system
Damiecki M, Naha R, Schaumkessel Y, Westhoff P, Atanelov N, Stefanski A, Petzsch P, Stühler K, Köhrer K, Weber A, Anand R, Reichert A, Kondadi A
Life Science Alliance 2024;7(12):e202403038
Life Science Alliance 2024;7(12):e202403038
MIC26 and MIC27 are bona fide subunits of the MICOS complex in mitochondria and do not exist as glycosylated apolipoproteins
Ruzzenente B, Lubeck M, Derkum N, Naha R, Strohm R, Driessen M, Belgardt B, Roden M, Stühler K, Anand R, Reichert A, Kondadi A
PLOS ONE 2023;18(6):e0286756
PLOS ONE 2023;18(6):e0286756
Colocalization for super-resolution microscopy via optimal transport
Tameling C, Stoldt S, Stephan T, Naas J, Jakobs S, Munk A
Nature Computational Science 2021;1(3):199-211
Nature Computational Science 2021;1(3):199-211
MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes
Anand R, Kondadi A, Meisterknecht J, Golombek M, Nortmann O, Riedel J, Peifer-Weiß L, Brocke-Ahmadinejad N, Schlütermann D, Stork B, Eichmann T, Wittig I, Reichert A
Life Science Alliance 2020;3(10):e202000711
Life Science Alliance 2020;3(10):e202000711
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
Narendra D, Sekine S, Poulton J, Springer D, Dombi E, Wu B, Shammas M, Nguyen D, Huang X, Liu Y
Human Molecular Genetics 2020;29(9):1547-1567
Human Molecular Genetics 2020;29(9):1547-1567
Cristae undergo continuous cycles of membrane remodelling in a MICOS ‐dependent manner
Kondadi A, Anand R, Hänsch S, Urbach J, Zobel T, Wolf D, Segawa M, Liesa M, Shirihai O, Weidtkamp‐Peters S, Reichert A
EMBO reports 2020;21(3)
EMBO reports 2020;21(3)
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10
Huang X, Wu B, Nguyen D, Liu Y, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra D
Human Molecular Genetics 2018
Human Molecular Genetics 2018
Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells
Liesa M, Anand R, Strecker V, Urbach J, Wittig I, Reichert A
PLOS ONE 2016;11(8):e0160258
PLOS ONE 2016;11(8):e0160258
APOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria
Cobine P, Weber T, Koob S, Heide H, Wittig I, Head B, van der Bliek A, Brandt U, Mittelbronn M, Reichert A
PLoS ONE 2013;8(5):e63683
PLoS ONE 2013;8(5):e63683
Tissue Profiling of the Mammalian Central Nervous System Using Human Antibody-based Proteomics
Mulder J, Björling E, Jonasson K, Wernérus H, Hober S, Hökfelt T, Uhlén M
Molecular & Cellular Proteomics 2009;8(7):1612-1622
Molecular & Cellular Proteomics 2009;8(7):1612-1622
Systematically generated antibodies against human gene products: High throughput screening on sections from the rat nervous system
Mulder J, Wernérus H, Shi T, Pontén F, Hober S, Uhlén M, Hökfelt T
Neuroscience 2007;146(4):1689-1703
Neuroscience 2007;146(4):1689-1703
No comments: Submit comment
Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in Rh30 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-APOOL antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
- Sample type
- Human
