16143-1-AP
antibody from Proteintech Group
Targeting: ATP6V1G1
ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10
Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 16143-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16143-1-AP, RRID:AB_2062686
- Product name
- ATP6V1G1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATP6V1G1 antibody (Cat. #16143-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Overcoming lysosomal barrier via V-ATPase: an exosome-based co-delivery platform for combined chemo/RNAi therapy against breast cancer.
PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis.
The m(6)A demethylase FTO links TLR7 to mitochondrial oxidation driving age-associated B cell formation in systemic lupus erythematosus.
Refining the Rab7-V1G1 axis to mitigate iron deposition: Protective effects of quercetin in alcoholic liver disease.
HPS6 Deficiency Leads to Reduced Vacuolar-Type H(+)-ATPase and Impaired Biogenesis of Lamellar Bodies in Alveolar Type II Cells.
Plasma exosomes impair microglial degradation of α-synuclein through V-ATPase subunit V1G1.
Protein expression patterns and metal metabolites in a protogynous hermaphrodite fish, the ricefield eel (Monopterus albus).
Reversible assembly and disassembly of V-ATPase during the lysosome regeneration cycle.
The proteomic landscape of synaptic diversity across brain regions and cell types.
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H+-ATPase.
A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes.
Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo.
A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.
Fast and cloning-free CRISPR/Cas9-mediated genomic editing in mammalian cells.
Liu K, Xiong T, Wang X, Wang T, Wang Y, Lei M, Shao L, Zhang L, Zhu Y
Journal of nanobiotechnology 2026 Mar 28;24(1)
Journal of nanobiotechnology 2026 Mar 28;24(1)
PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis.
Gutiérrez-Galindo E, Jursik K, Frey Y, Meyer F, Hausser A
iScience 2025 Sep 19;28(9):113408
iScience 2025 Sep 19;28(9):113408
The m(6)A demethylase FTO links TLR7 to mitochondrial oxidation driving age-associated B cell formation in systemic lupus erythematosus.
Zeng Q, Li L, Li X, Qin L, Feng T, Zhu Y, Wang J, Zou Y, Su J, Dong G, Xia W, Xu T, Zhang G, Cui Y, Lin H, Li X, Li Y
Science translational medicine 2025 Nov 5;17(823):eadu6015
Science translational medicine 2025 Nov 5;17(823):eadu6015
Refining the Rab7-V1G1 axis to mitigate iron deposition: Protective effects of quercetin in alcoholic liver disease.
Lin H, Guo X, Liu J, Chen L, Chen H, Zhao Y, Li H, Rong S, Yao P
The Journal of nutritional biochemistry 2025 Jan;135:109767
The Journal of nutritional biochemistry 2025 Jan;135:109767
HPS6 Deficiency Leads to Reduced Vacuolar-Type H(+)-ATPase and Impaired Biogenesis of Lamellar Bodies in Alveolar Type II Cells.
Hao Z, Wang H, Zhou Z, Yang Q, Zhang B, Ma J, Li W
American journal of respiratory cell and molecular biology 2024 Oct;71(4):442-452
American journal of respiratory cell and molecular biology 2024 Oct;71(4):442-452
Plasma exosomes impair microglial degradation of α-synuclein through V-ATPase subunit V1G1.
Li Y, Wang Y, Kou L, Yin S, Chi X, Sun Y, Wu J, Jin Z, Zhou Q, Zou W, Wang T, Xia Y
CNS neuroscience & therapeutics 2024 May;30(5):e14738
CNS neuroscience & therapeutics 2024 May;30(5):e14738
Protein expression patterns and metal metabolites in a protogynous hermaphrodite fish, the ricefield eel (Monopterus albus).
He Z, Xiao F, Yang D, Deng F, Ding W, He Z, Wang S, Chen Q, Wang H, Chen M, Gao K, Xiong J, Tang Z, Zhang M, Yan T
BMC genomics 2024 May 21;25(1):500
BMC genomics 2024 May 21;25(1):500
Reversible assembly and disassembly of V-ATPase during the lysosome regeneration cycle.
Sava I, Davis LJ, Gray SR, Bright NA, Luzio JP
Molecular biology of the cell 2024 May 1;35(5):ar63
Molecular biology of the cell 2024 May 1;35(5):ar63
The proteomic landscape of synaptic diversity across brain regions and cell types.
van Oostrum M, Blok TM, Giandomenico SL, Tom Dieck S, Tushev G, Fürst N, Langer JD, Schuman EM
Cell 2023 Nov 22;186(24):5411-5427.e23
Cell 2023 Nov 22;186(24):5411-5427.e23
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Ou M, Cho HY, Fu J, Thein TZ, Wang W, Swenson SD, Minea RO, Stathopoulos A, Schönthal AH, Hofman FM, Tang L, Chen TC
Autophagy 2023 Dec;19(12):3169-3188
Autophagy 2023 Dec;19(12):3169-3188
Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H+-ATPase.
Terglane J, Menche D, Gerke V
PloS one 2022;17(6):e0270299
PloS one 2022;17(6):e0270299
A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes.
Bertolini I, Terrasi A, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Braidotti P, Todoerti K, Ferrero S, Caroli M, Ottobrini L, Vaccari T, Vaira V
EBioMedicine 2019 Mar;41:225-235
EBioMedicine 2019 Mar;41:225-235
Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo.
Terrasi A, Bertolini I, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Bosari S, Caroli M, Ottobrini L, Vaccari T, Vaira V
EBioMedicine 2019 Mar;41:214-224
EBioMedicine 2019 Mar;41:214-224
A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.
Rao VK, Zavala G, Deb Roy A, Mains RE, Eipper BA
Journal of cellular physiology 2019 Jun;234(6):8683-8697
Journal of cellular physiology 2019 Jun;234(6):8683-8697
Fast and cloning-free CRISPR/Cas9-mediated genomic editing in mammalian cells.
Manna PT, Davis LJ, Robinson MS
Traffic (Copenhagen, Denmark) 2019 Dec;20(12):974-982
Traffic (Copenhagen, Denmark) 2019 Dec;20(12):974-982
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 16143-1-AP(ATP6V1G1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 16143-1-AP(ATP6V1G1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The ATP6V1G1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATP6V1G1. This antibody recognizes human, mouse, rat antigen. The ATP6V1G1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.