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- Antigen structure
- References [22]
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- Product number
- 14881-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14881-1-AP, RRID:AB_2218248
- Product name
- YWHAZ antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated YWHAZ antibody (Cat. #14881-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14-3-3η.
TMEM65 promotes gastric tumorigenesis by targeting YWHAZ to activate PI3K-Akt-mTOR pathway and is a therapeutic target.
A prominent role of LncRNA H19 in H. pylori CagA induced DNA damage response and cell malignancy.
Over-expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice.
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
AKT2 reduces IFNβ1 production to modulate antiviral responses and systemic lupus erythematosus.
Lnc524369 promotes hepatocellular carcinoma progression and predicts poor survival by activating YWHAZ-RAF1 signaling.
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity.
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Comparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines.
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
High Dietary Fat Consumption Impairs Axonal Mitochondrial Function In Vivo.
YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.
Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
YWHAZ Binds to TRIM21 but Is Not Involved in TRIM21-stimulated Osteosarcoma Cell Proliferation.
TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer.
The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma.
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia.
miR-155 downregulates ErbB2 and suppresses ErbB2-induced malignant transformation of breast epithelial cells.
Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5(+) liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.
Hu T, Hu FJ, Huang H, Zhang ZY, Qiao YM, Huang WX, Wang YC, Tang XY, Lai SQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116542
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116542
TMEM65 promotes gastric tumorigenesis by targeting YWHAZ to activate PI3K-Akt-mTOR pathway and is a therapeutic target.
Shi L, Wang X, Guo S, Gou H, Shang H, Jiang X, Wei C, Wang J, Li C, Wang L, Zhao Z, Yu W, Yu J
Oncogene 2024 Mar;43(13):931-943
Oncogene 2024 Mar;43(13):931-943
A prominent role of LncRNA H19 in H. pylori CagA induced DNA damage response and cell malignancy.
He X, Huang T, Wang Q, Bao L, Wang Z, Song H, Li Y, Zhou J, Zhao Y, Xie Y
Scientific reports 2024 Jun 20;14(1):14185
Scientific reports 2024 Jun 20;14(1):14185
Over-expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice.
Postic G, Solarz J, Loubière C, Kandiah J, Sawmynaden J, Adam F, Vilaire M, Léger T, Camadro JM, Victorino DB, Potier MC, Bun E, Moroy G, Kauskot A, Christophe O, Janel N
Journal of cellular and molecular medicine 2023 Aug;27(15):2228-2238
Journal of cellular and molecular medicine 2023 Aug;27(15):2228-2238
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
Zhao Y, Li S, Chen Y, Wang Y, Wei Y, Zhou T, Zhang Y, Yang Y, Chen L, Liu Y, Hu C, Zhou B, Ding Q
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
AKT2 reduces IFNβ1 production to modulate antiviral responses and systemic lupus erythematosus.
Zheng X, Xiao J, Jiang Q, Zheng L, Liu C, Dong C, Zheng Y, Ni P, Zhang C, Zhang F, Zhong R, Ding H, Wang Q, Qiu Y, Gao M, Ding J, Shen N, Wei B, Wang H
The EMBO journal 2022 Mar 15;41(6):e108016
The EMBO journal 2022 Mar 15;41(6):e108016
Lnc524369 promotes hepatocellular carcinoma progression and predicts poor survival by activating YWHAZ-RAF1 signaling.
Zheng W, Shen GL, Xu KY, Yin QQ, Hui TC, Zhou ZW, Xu CA, Wang SH, Wu WH, Shi LF, Pan HY
World journal of gastrointestinal oncology 2022 Jan 15;14(1):253-264
World journal of gastrointestinal oncology 2022 Jan 15;14(1):253-264
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity.
Zhang Z, Chen C, Yang F, Zeng YX, Sun P, Liu P, Li X
Molecular cell 2022 Aug 4;82(15):2844-2857.e10
Molecular cell 2022 Aug 4;82(15):2844-2857.e10
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Comparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines.
Michalik S, Siegerist F, Palankar R, Franzke K, Schindler M, Reder A, Seifert U, Cammann C, Wesche J, Steil L, Hentschker C, Gesell-Salazar M, Reisinger E, Beer M, Endlich N, Greinacher A, Völker U
Haematologica 2022 Apr 1;107(4):947-957
Haematologica 2022 Apr 1;107(4):947-957
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
Zhang T, Beeharry MK, Wang Z, Zhu Z, Li J, Li C
International journal of biological sciences 2021;17(7):1629-1643
International journal of biological sciences 2021;17(7):1629-1643
High Dietary Fat Consumption Impairs Axonal Mitochondrial Function In Vivo.
Sajic M, Rumora AE, Kanhai AA, Dentoni G, Varatharajah S, Casey C, Brown RDR, Peters F, Hinder LM, Savelieff MG, Feldman EL, Smith KJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 May 12;41(19):4321-4334
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 May 12;41(19):4321-4334
YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.
Mei J, Liu Y, Yu X, Hao L, Ma T, Zhan Q, Zhang Y, Zhu Y
Cell death discovery 2021 Aug 27;7(1):221
Cell death discovery 2021 Aug 27;7(1):221
Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes.
O'Brien PD, Guo K, Eid SA, Rumora AE, Hinder LM, Hayes JM, Mendelson FE, Hur J, Feldman EL
Disease models & mechanisms 2020 Jan 24;13(2)
Disease models & mechanisms 2020 Jan 24;13(2)
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
YWHAZ Binds to TRIM21 but Is Not Involved in TRIM21-stimulated Osteosarcoma Cell Proliferation.
Zeng QZ, Liu WT, Lu JL, Liu XH, Zhang YF, Liu LX, Gao XJ
Biomedical and environmental sciences : BES 2018 Mar;31(3):186-196
Biomedical and environmental sciences : BES 2018 Mar;31(3):186-196
TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer.
Sheng N, Yan L, Wu K, You W, Gong J, Hu L, Tan G, Chen H, Wang Z
Cell death & disease 2018 Mar 14;9(3):402
Cell death & disease 2018 Mar 14;9(3):402
The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma.
Zhao JF, Zhao Q, Hu H, Liao JZ, Lin JS, Xia C, Chang Y, Liu J, Guo AY, He XX
Molecular therapy. Nucleic acids 2018 Jun 1;11:538-553
Molecular therapy. Nucleic acids 2018 Jun 1;11:538-553
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
Zhong X, Tian S, Zhang X, Diao X, Dong F, Yang J, Li Z, Sun L, Wang L, He X, Wu G, Hu X, Wang L, Song L, Zhang H, Pan X, Li A, Gao P
EMBO reports 2017 May;18(5):809-825
EMBO reports 2017 May;18(5):809-825
c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia.
Su R, Gong JN, Chen MT, Song L, Shen C, Zhang XH, Yin XL, Ning HM, Liu B, Wang F, Ma YN, Zhao HL, Yu J, Zhang JW
Oncotarget 2016 Nov 22;7(47):77430-77443
Oncotarget 2016 Nov 22;7(47):77430-77443
miR-155 downregulates ErbB2 and suppresses ErbB2-induced malignant transformation of breast epithelial cells.
He XH, Zhu W, Yuan P, Jiang S, Li D, Zhang HW, Liu MF
Oncogene 2016 Nov 17;35(46):6015-6025
Oncogene 2016 Nov 17;35(46):6015-6025
Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5(+) liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.
Lei ZJ, Wang J, Xiao HL, Guo Y, Wang T, Li Q, Liu L, Luo X, Fan LL, Lin L, Mao CY, Wang SN, Wei YL, Lan CH, Jiang J, Yang XJ, Liu PD, Chen DF, Wang B
Oncogene 2015 Jun 11;34(24):3188-98
Oncogene 2015 Jun 11;34(24):3188-98
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The YWHAZ antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human YWHAZ. This antibody recognizes human,mouse,rat antigen. The YWHAZ antibody has been validated for the following applications: ELISA, WB analysis.
