ABIN968117

antibody from antibodies-online

Targeting: ALOX5 5-LOX

Western blot (Recommended by provider)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN968117

Provider

antibodies-online

Product name

anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 442-590) antibody

Antibody type

Monoclonal

Antigen

Human 5-Lipoxygenase

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

AA 442-590

Isotype

IgG

Antibody clone number

4C6-1

Vial size

150 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

Elevated levels of cyclooxygenase-2 in antigen-stimulated mast cells is associated with minimal activation of p38 mitogen-activated protein kinase.

Hundley TR, Prasad AR, Beaven MA
Journal of immunology (Baltimore, Md. : 1950) 2001 Aug 1;167(3):1629-36

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New induction of leukotriene A(4) hydrolase by interleukin-4 and interleukin-13 in human polymorphonuclear leukocytes.

Zaitsu M, Hamasaki Y, Matsuo M, Kukita A, Tsuji K, Miyazaki M, Hayasaki R, Muro E, Yamamoto S, Kobayashi I, Ichimaru T, Kohashi O, Miyazaki S
Blood 2000 Jul 15;96(2):601-9

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Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase.

Lepley RA, Muskardin DT, Fitzpatrick FA
The Journal of biological chemistry 1996 Mar 15;271(11):6179-84

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5-Lipoxygenase contains a functional Src homology 3-binding motif that interacts with the Src homology 3 domain of Grb2 and cytoskeletal proteins.

Lepley RA, Fitzpatrick FA
The Journal of biological chemistry 1994 Sep 30;269(39):24163-8

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Molecular cloning and amino acid sequence of human 5-lipoxygenase.

Matsumoto T, Funk CD, Rådmark O, Höög JO, Jörnvall H, Samuelsson B
Proceedings of the National Academy of Sciences of the United States of America 1988 Jan;85(1):26-30