66326-1-Ig

antibody from Proteintech Group

Targeting: ALOX5 5-LOX

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66326-1-Ig

Provider

Proteintech Group

Product name

5 Lipoxygenase antibody

Antibody type

Monoclonal

Description

5 Lipoxygenase antibody (Cat. #66326-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3B1B7

Vial size

20ul, 150ul

References

Submitted references

Structural characterization and multi-omics analysis of novel Saposhnikovia divaricata (Turcz.) Schischk acidic heteropolysaccharide alleviating acute liver injury.

Sun X, Zhang T, Zhu W, Jiang X, Wang S, Zhao Y, Bian X
International journal of biological macromolecules 2026 Jan;339(Pt 1):149819

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An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.

Ren Z, Wang Y, Cheng C, Zhang Y, Liu Y, Wei Y, Liu Z, Zhang J, Shi Z, Yu J, Hu W, Ye J, Wang J, Qiu S, Li G
Free radical biology & medicine 2026 Feb 1;243:260-275

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Radioiodination of Two Carborane-Based Dual Cyclooxygenase-2/5-Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation.

Schädlich J, Ullrich M, Haase-Kohn C, Wodtke R, Braun S, Molitor M, Hofmann B, Steinhilber D, Kopka K, Hey-Hawkins E, Pietzsch J, Laube M
Chembiochem : a European journal of chemical biology 2026 Apr 14;27(7):e202600004

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Control of ALOX5 expression in monocytic cells using a synthetic riboswitch.

Bruckhoff RW, Oberlis JH, Steinhilber D, Suess B
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159671

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Potential and Optimization of Mammalian Splice Riboswitches for the Regulation of Exon Skipping-Dependent Gene Expression and Isoform Switching within the ALOX5 Gene.

Bruckhoff RW, Becker O, Steinhilber D, Suess B
ACS synthetic biology 2025 Mar 21;14(3):804-818

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Integratomic investigation to assess the liver lipidomic and antiinflammatory activity of lupin protein hydrolysate.

Casati S, Dei Cas M, d'Adduzio L, Cruz-Chamorro I, Santos-Sánchez G, Bollati C, Fanzaga M, Pedroche J, Millán-Linares MDC, Roda G, Carrillo-Vico A, Lammi C
NPJ science of food 2025 Jul 28;9(1):154

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Arctoscopusjaponicus lipids inhibit anti-inflammatory efficacy via eicosanoid synthesis pathways in activated macrophages.

Rod-In W, Talapphet N, Jung SK, Park WJ
Fish & shellfish immunology 2025 Dec;167:110698

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Bioactive compounds in the modulation of oxidative stress in monocytes and macrophages.

Kushwaha R, Alugoju P, Anthikapalli NVA, Sharma R, Sedlářová M, Pospíšil P, Tamasi G, Bonechi C, Rossi C, Prasad A
Scientific reports 2025 Aug 31;15(1):32012

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MLL-AF4 upregulates 5-lipoxygenase expression in t(4;11) leukemia cells via the ALOX5 core promoter.

Hyprath M, Molitor M, Schweighöfer I, Marschalek R, Steinhilber D
Frontiers in pharmacology 2024;15:1520507

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Identification of potential key lipid metabolism-related genes involved in tubular injury in diabetic kidney disease by bioinformatics analysis.

Fan Y, He J, Shi L, Zhang M, Chen Y, Xu L, Han N, Jiang Y
Acta diabetologica 2024 Aug;61(8):1053-1068

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Crizotinib and its enantiomer suppress ferroptosis by decreasing PE-O-PUFA content.

Cen SY, Lin F, Li X, Hu Y, Liu JP, Xue Z, Gao Y, Sun YP, Zhu S, Dang Y, Zhao Y, Yuan HX
Cell death discovery 2024 Aug 12;10(1):360

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Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis.

Yao T, Yao YY, Wang JZ, Jiang SM, Li LJ
The Kaohsiung journal of medical sciences 2024 Apr;40(4):360-373

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Three-dimensional growth reveals fine-tuning of 5-lipoxygenase by proliferative pathways in cancer.

Göbel T, Goebel B, Hyprath M, Lamminger I, Weisser H, Angioni C, Mathes M, Thomas D, Kahnt AS
Life science alliance 2023 May;6(5)

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Knock-out of 5-lipoxygenase in overexpressing tumor cells-consequences on gene expression and cellular function.

Weisser H, Göbel T, Melissa Krishnathas G, Kreiß M, Angioni C, Sürün D, Thomas D, Schmid T, Häfner AK, Kahnt AS
Cancer gene therapy 2023 Jan;30(1):108-123