MAB3661
antibody from Novus Biologicals
Targeting: CCL21
6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- MAB3661 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal CCL21/6Ckine Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CCL21/6Ckine in ELISAs and Western blots. In Western blots, shows 100% cross-reactivity with recombinant human (rh) CCL24. Under reducing conditions, shows approximately 10-50% cross-reactivity with rhCCL2, 8, 13, 28, and rmCCL2. Does not cross-react with rhCCL1, 3, 4, 5, 7, 9, 11, 14a, 15, 17, 18, 19, 20, 22, 23, 25, rmCCL1, 3, 4, 6, 7, 9, 11, 12, 19, 20, 21, 22, 24, 25, 28, or rrCCL20.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Lymphatic specific disruption in the fine structure of heparan sulfate inhibits dendritic cell traffic and functional T cell responses in the lymph node.
Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces.
Yin X, Johns SC, Kim D, Mikulski Z, Salanga CL, Handel TM, Macal M, Zúñiga EI, Fuster MM
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 1;192(5):2133-42
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 1;192(5):2133-42
Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces.
Woolf E, Grigorova I, Sagiv A, Grabovsky V, Feigelson SW, Shulman Z, Hartmann T, Sixt M, Cyster JG, Alon R
Nature immunology 2007 Oct;8(10):1076-85
Nature immunology 2007 Oct;8(10):1076-85
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