17840-1-AP

antibody from Proteintech Group

Targeting: AHR bHLHe76

Provider product page for 17840-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [47]
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Validations
Western blot [1]
Immunohistochemistry [1]

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Product number: 17840-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#17840-1-AP, RRID:AB_2226163
Product name: AHR antibody
Antibody type: Polyclonal
Description: KD/KO validated AHR antibody (Cat. #17840-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

AHR protein structure - 17840-1-AP shown in red.

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Formononetin attenuates cigarette smoke-induced COPD in mice by suppressing inflammation, endoplasmic reticulum stress, and apoptosis in bronchial epithelial cells via AhR/CYP1A1 and AKT/mTOR signaling pathways.

Li X, Jiang X, Zeng R, Lai X, Wang J, Liu H, Wu H, He J, Liu L, Zhu Z, Li J, Liang X
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AhR-STAT3-HO-1/COX-2 signalling pathway may restrict ferroptosis and improve hMSC accumulation and efficacy in mouse liver.

Han L, Ma C, Wu Z, Xu H, Li H, Pan G
British journal of pharmacology 2024 Jan;181(1):125-141

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Ninjinyoeito Prevents Onset of Depression-Like Behavior and Reduces Hippocampal iNOS Expression in Senescence-Accelerated Mouse Prone 8 Mice.

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Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.

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Bridging of host-microbiota tryptophan partitioning by the serotonin pathway in fungal pneumonia.

Renga G, D'Onofrio F, Pariano M, Galarini R, Barola C, Stincardini C, Bellet MM, Ellemunter H, Lass-Flörl C, Costantini C, Napolioni V, Ehrlich AK, Antognelli C, Fini M, Garaci E, Nunzi E, Romani L
Nature communications 2023 Sep 16;14(1):5753

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Chen M, Shu Y, Li Q, Kang Z, Liu T, Zhou H, Huang W, Zhang W
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Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.

Chen C, Sun S, Zhao J, Wu Q, He W, Sun W
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AhR regulates VEGF expression by promoting STAT1 transcriptional activity, thereby affecting endothelial angiogenesis in acute limb ischemia.

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Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.

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Betacoronaviruses SARS-CoV-2 and HCoV-OC43 infections in IGROV-1 cell line require aryl hydrocarbon receptor.

Yousefi M, Lee WS, Chan WOY, He W, Mah MG, Yong CL, Deerain JM, Wang L, Arcinas C, Yan B, Tan D, Sia WR, Gamage AM, Yang J, Hsu AC, Li S, Linster M, Yang X, Ghosh S, Anderson DE, Smith GJD, Tan CW, Wang LF, Ooi YS
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Sensory nerves directly promote osteoclastogenesis by secreting peptidyl-prolyl cis-trans isomerase D (Cyp40).

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Bone research 2023 Dec 14;11(1):64

Fine particulate matter (PM2.5) induces inhibitory memory alveolar macrophages through the AhR/IL-33 pathway.

Liu Y, Yuan Q, Zhang X, Chen Z, Jia X, Wang M, Xu T, Wang Z, Jiang J, Ma Q, Zhang M, Huang M, Ji N
Cellular immunology 2023 Apr;386:104694

ZNF165 Is Involved in the Regulation of Immune Microenvironment and Promoting the Proliferation and Migration of Hepatocellular Carcinoma by AhR/CYP1A1.

Liu P, Zhou Y, Dong X, Zheng B, Liang B, Liang R, Liu Z, Li L, Gong P
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Zeng X, Xia S, Yan X, Hu C, An K, Luo L
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Kunitomi C, Harada M, Kusamoto A, Azhary JM, Nose E, Koike H, Xu Z, Urata Y, Takahashi N, Wada-Hiraike O, Hirota Y, Koga K, Fujii T, Osuga Y
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Shi Z, Lei H, Chen G, Yuan P, Cao Z, Ser HL, Zhu X, Wu F, Liu C, Dong M, Song Y, Guo Y, Chen C, Hu K, Zhu Y, Zeng XA, Zhou J, Lu Y, Patterson AD, Zhang L
mSystems 2021 Feb 23;6(1)

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Li X, Lu C, Fan D, Lu X, Xia Y, Zhao H, Xu H, Zhu Y, Li J, Liu H, Xiao C
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Fine Particulate Matter (PM(2).(5)) Promotes CD146 Expression in Alveolar Epithelial Cells and Cryptococcus neoformans Pulmonary Infection.

Sun Z, Ji N, Jiang J, Tao Y, Zhang E, Yang X, Wang Z, Chen Z, Huang M, Zhang M
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Tangshen formula modulates gut Microbiota and reduces gut-derived toxins in diabetic nephropathy rats.

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Xu Y, Fang H, Xu Q, Xu C, Yang L, Huang C
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Xiong J, Zhang X, Zhang Y, Wu B, Fang L, Wang N, Yi H, Chang N, Chen L, Zhang J
Experimental cell research 2020 Nov 1;396(1):112288

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Aryl Hydrocarbon Receptor in Cutaneous Vascular Endothelial Cells Restricts Psoriasis Development by Negatively Regulating Neutrophil Recruitment.

Zhu Z, Chen J, Lin Y, Zhang C, Li W, Qiao H, Fu M, Dang E, Wang G
The Journal of investigative dermatology 2020 Jun;140(6):1233-1243.e9

Both IDO1 and TDO contribute to the malignancy of gliomas via the Kyn-AhR-AQP4 signaling pathway.

Du L, Xing Z, Tao B, Li T, Yang D, Li W, Zheng Y, Kuang C, Yang Q
Signal transduction and targeted therapy 2020 Feb 21;5(1):10

The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.

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Journal of ethnopharmacology 2020 Apr 6;251:112549

A Network Pharmacology Approach for Uncovering the Osteogenic Mechanisms of Psoralea corylifolia Linn.

Ge L, Cheng K, Han J
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2160175

Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice.

Xia H, Zhu X, Zhang X, Jiang H, Li B, Wang Z, Li D, Jin Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109287

Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats.

Dong M, Xu X, Huang Q, Lei H, Xu G, Ma J, Hatzakis E, Wang X, Zhang L
Chemical research in toxicology 2019 Nov 18;32(11):2320-2328

Tetrandrine enhances the ubiquitination and degradation of Syk through an AhR-c-src-c-Cbl pathway and consequently inhibits osteoclastogenesis and bone destruction in arthritis.

Jia Y, Tao Y, Lv C, Xia Y, Wei Z, Dai Y
Cell death & disease 2019 Jan 15;10(2):38

Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes.

Liu Q, Wu J, Song J, Liang P, Zheng K, Xiao G, Liu L, Zouboulis CC, Lei T
International journal of molecular medicine 2017 Oct;40(4):1029-1036

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Chai J, Du X, Chen S, Feng X, Cheng Y, Zhang L, Gao Y, Li S, He X, Wang R, Zhou X, Yang Y, Luo W, Chen W
International journal of clinical and experimental medicine 2015;8(2):1691-702

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Hepatic expression of detoxification enzymes is decreased in human obstructive cholestasis due to gallstone biliary obstruction.

Chai J, Feng X, Zhang L, Chen S, Cheng Y, He X, Yang Y, He Y, Wang H, Wang R, Chen W
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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: MCF7 cells were subjected to SDS PAGE followed by western blot with 17840-1-AP(AHR antibody) at dilution of 1:1000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The AHR antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AHR. This antibody recognizes human, mouse antigen. The AHR antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 17840-1-AP.pdf

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