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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [101]
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- Product number
- 67785-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- AHR antibody
- Antibody type
- Monoclonal
- Description
- AHR antibody (Cat. #67785-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2D1F9
- Vial size
- 20ul, 150ul
Submitted references Modified Jiaoqi powder ameliorates ulcerative colitis through gut microbiota-tryptophan metabolism-AhR signaling modulating-ILC2/ILC3 balance.
Aryl hydrocarbon receptor in club cells drives Th17-mediated lung injury following inhalation exposure to environmentally persistent free radicals.
Benzo[a]pyrene exacerbates bone destruction by inhibiting Treg differentiation, impairing Treg function and promoting osteoclastogenesis in rats with collagen-induced arthritis.
Therapeutic potential of Isatidis Radix alkaloids in RSV pneumonia: A focus on AhR-mediated pulmonary barrier repair.
Ligilactobacillus murinus alleviates binge-eating behavior by restoring serotonin metabolism.
Proline/serine-rich coiled-coil 1 alleviates atherosclerosis via remodeling tryptophan metabolism mediated by Akkermansia muciniphila.
Asiaticoside protects against PDF-induced peritoneal fibrosis via suppression of AhR/Nrf2-mediated MMT and oxidative stress.
Transcriptomic Insights Into Alzheimer's Disease: Differentially Expressed Genes and Cholesterol Metabolism.
Differential Effects of Saturated and Unsaturated Fatty Acids on Colorectal Cancer via IDO1 Signaling.
Dietary advanced glycation products combined with chronic restraint stress induced anxiety-like and depression-like behaviors in male mice.
Loganic Acid Ameliorates Rheumatoid Arthritis via the Lactobacillus murinus-Inodole-3-Acetic Acid-AhR-IL-10 Axis.
Molecular crosstalk between PPARγ and AhR determines the endocrine-disrupting profile of amiodarone (AMD) in hippocampal neurons.
The Scutellaria baicalensis-Coptis chinensis herb pair ameliorates ulcerative colitis via integrated modulation of the aryl hydrocarbon receptor/NLRP3 inflammasome axis with tryptophan metabolites.
Zanthoxylum bungeanum essential oil alleviates DSS-induced ulcerative colitis in mice by modulating gut microbiota-dependent AhR/Nrf2 signaling.
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Fangji Huangqi Tang alleviated chronic kidney disease by regulating intestinal bacteria to inhibit the AHR/ROS pathway.
Gut metabolite indole-3-acetic acid aggravates neuropsychiatric lupus via the AHR/STAT3 pathway in microglia.
Differential Toxicity of Water-Soluble Versus Water-Insoluble Components of Cowshed PM2.5 on Ovarian Granulosa Cells and the Regulatory Role of Txnip in Overall Toxicity.
Microbiota-driven tryptophan metabolism and AhR triggered intestinal stem cell differentiation: mechanisms of huangqin decoction in ulcerative colitis repair.
Regulating Tumor Metabolic Reprogramming with Biomimetic Co-Delivery of Simvastatin and Kynureninase for Immunotherapy.
Inducible CD147 up-regulation boosts extended SARS-CoV-2 infection triggering severe COVID-19 independent of ACE2.
Akkermansia muciniphila reduces neuroinflammation and Aβ deposition via tryptophan metabolism in the APP/PS1 mouse model of Alzheimer's disease.
Two orthobunyaviruses: OYAV and EBIV co-opt the AhR-CYP1A1 axis to suppress type I interferon responses.
Lycium Barbarum Polysaccharide Attenuates Staphylococcus aureus-Induced Mastitis via the Gut Microbiota-Derived Indole-3-Propionic Acid/AhR-IL-22-STAT3 Axis.
Lactobacillus paracasei ZJUZ2-3 inhibits gastrointestinal tumors via the IAA-induced AHR/MTDH/NF-κB axis.
Huangkui capsules regulate tryptophan metabolism to improve diabetic nephropathy through the Keap1/Nrf2/HO-1 pathway.
GPX4 knockdown suppresses M2 macrophage polarization in gastric cancer by modulating kynurenine metabolism.
Hydrogen regulates the aryl hydrocarbon receptor, improving bronchopulmonary dysplasia in neonatal rats and RLE-6TN cells exposed to hyperoxia.
Methionine ameliorates intestinal injury in senescence-accelerated mouse prone-8 mice by reducing sulfate-reducing bacteria and enhancing barrier function.
Quercetin ameliorates obesity and inflammation via microbial metabolite indole-3-propionic acid in high fat diet-induced obese mice.
Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis.
A Preliminary Study of the Relationship Between Zinc and the AhR Signaling Pathway During Palatal Development.
Long-term low-dose exposure to 9-chlorophenanthrene induces liver lipid accumulation via disrupting circadian rhythm.
Bifidobacterium longum subsp. longum B-53 Alleviated Abnormalities of Glycolipid Metabolism and Oxidative Stress in T2DM Mice Through Regulating Gut Microbiota and GLP-1 Secretion.
Aryl Hydrocarbon Receptor (AhR)-Independent Amiodarone (AMD) Toxicity in HepG2 Cell Line.
Targeting Tris(2,3-dibromopropyl) Isocyanurate-Induced Inflammation in Hippocampal Neurons In Vitro: Mechanistic Insights and Implications for Neurodegenerative Disease Prevention.
Quercetin protected the gut barrier in ulcerative colitis by activating aryl hydrocarbon receptor.
Carboxychalcones Based on Terephthalaldehydic Acid as Potential Neuroprotective Agents. Synthesis, Computational Study and Biological Evaluation.
Evaluating the Effects of Neburon Exposure on Ovarian Folliculogenesis Using Zebrafish and Mouse Granulosa Cell Line.
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
IDO1 inhibitors block septic cytokine storm by suppressing the IDO1-AHR-CYP1A1 axis.
Exposure to the prenatal enriched environment alters maternal gut microbiota and promotes embryonic neurodevelopment via activating the AHR-Src pathway.
Multi-omics study reveals gut microbiota dysbiosis and tryptophan metabolism alterations in GH-PitNET progression.
Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line.
Gut microbiota-derived indole-3-acetic acid ameliorates calcium oxalate renal stone formation via AHR/NF‑κB axis.
SLC7A5 regulates tryptophan uptake and PD‑L1 expression levels via the kynurenine pathway in ovarian cancer.
Cigarette smoke-induced attenuation of the prostaglandin transporter SLCO2A1 expression through aryl hydrocarbon receptor.
Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway.
Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice.
Engagement of peroxisome proliferator-activated receptor gamma (PPARγ) and mammalian target of rapamycin (mTOR) in the triclosan-induced disruption of Cyp450 enzyme activity in an in vitro model of mouse embryo fibroblasts (3T3-L1).
Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis.
Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea.
The aryl hydrocarbon receptor affects the inflammatory response of bone marrow mesenchymal stem cell via the hippo-YAP pathway to exacerbate systemic lupus erythematosus.
Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells.
Tryptophan derivatives as non-invasive diagnostic indicators for obesity-related MASLD in children and adolescents.
Aldehyde dehydrogenase ALDH3A1 rescues cigarette smoke-induced emphysema by conferring alveolar type 2 to type 1 cell transition.
Role of indoleamine 2,3-Dioxygenase 1 in modulating the malignant biological behavior of cervical cancer cells through the Tryptophan-Kynurenine pathway.
Hypoxia-induced PRMT1 methylates HIF2β to promote breast tumorigenesis via enhancing glycolytic gene transcription.
Spermidine attenuates chondrocyte inflammation and cellular pyroptosis through the AhR/NF-κB axis and the NLRP3/caspase-1/GSDMD pathway.
Baitouweng decoction alleviates ulcerative colitis by regulating tryptophan metabolism through DOPA decarboxylase promotion.
Targeting mitochondrial dysfunction in atopic dermatitis with trilinolein: A triacylglycerol from the medicinal plant Cannabis fructus.
Microbial Tryptophan Metabolites Ameliorate Ovariectomy-Induced Bone Loss by Repairing Intestinal AhR-Mediated Gut-Bone Signaling Pathway.
Multi-omics insights into anti-colitis benefits of the synbiotic and postbiotic derived from wheat bran arabinoxylan and Limosilactobacillus reuteri.
Elastin-derived peptides (EDPs) affect gene and protein expression in human mesenchymal stem cells (hMSCs) - preliminary study.
IDO1 inhibitors are synergistic with CXCL10 agonists in inhibiting colon cancer growth.
Tumor-colonized Streptococcus mutans metabolically reprograms tumor microenvironment and promotes oral squamous cell carcinoma.
Low-Medium Polarity Ginsenosides from Wild Ginseng Improves Immunity by Activating the AhR/MAPK Pathway through Tryptophan Metabolism Driven by Gut Microbiota.
StemRegenin 1 attenuates the RANKL-induced osteoclastogenesis via inhibiting AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway.
Roles of AhR/CYP1s signaling pathway mediated ROS production in uremic cardiomyopathy.
Metabolic landscape of head and neck squamous cell carcinoma informs a novel kynurenine/Siglec-15 axis in immune escape.
Role of 4-Thiazolidinone-Pyrazoline/Indoline Hybrids Les-4369 and Les-3467 in BJ and A549 Cell Lines.
Activation of aryl hydrocarbon receptor (AhR) alleviates depressive-like behaviors in LPS-induced mice.
Multi-omics approaches for the understanding of therapeutic mechanism for Huang-Qi-Long-Dan Granule against ischemic stroke.
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Microbiota-derived I3A protects the intestine against radiation injury by activating AhR/IL-10/Wnt signaling and enhancing the abundance of probiotics.
Intracellular tacrolimus concentration correlates with impaired renal function through regulation of the IS-AHR-ABC transporter in peripheral blood mononuclear cells.
Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy.
Hesperetin protects hippocampal neurons from the neurotoxicity of Aflatoxin B1 in mice.
Aucubin ameliorates atherosclerosis by modulating tryptophan metabolism and inhibiting endothelial-mesenchymal transitions via gut microbiota regulation.
Cannabidiol Suppresses Metastatic Castration-Resistant Prostate Cancer Progression and Recurrence through Modulating Tryptophan Catabolism.
Identification of potential key lipid metabolism-related genes involved in tubular injury in diabetic kidney disease by bioinformatics analysis.
CDKs Functional Analysis in Low Proliferating Early-Stage Pancreatic Ductal Adenocarcinoma.
Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis.
Pyrrolidinedione-thiazolidinone hybrid molecules with potent cytotoxic effect in squamous cell carcinoma SCC-15 cells.
CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis.
Involvement of estrogen receptor alpha (ERα) and impairment of steroidogenesis after exposure to tris(2,3-dibromopropyl) isocyanurate (TBC) in mouse spermatogenic (GC-1 spg) cells in vitro.
Knockdown of IL4I1 Improved High Glucose-evoked Insulin Resistance in HepG2 Cells by Alleviating Inflammation and Lipotoxicity Through AHR Activation.
Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration.
Gut microbiota-derived 3-phenylpropionic acid promotes intestinal epithelial barrier function via AhR signaling.
Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism.
Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis.
Crosstalk between the aryl hydrocarbon receptor (AhR) and the peroxisome proliferator-activated receptor gamma (PPARγ) as a key factor in the metabolism of silver nanoparticles in neuroblastoma (SH-SY5Y) cells in vitro.
Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma.
Assessment of intestinal status in MPL(W515L) mutant myeloproliferative neoplasms mice model.
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM(2.5)-induced lung injury: a comparative study.
MBL Binding with AhR Controls Th17 Immunity in Silicosis-Associated Lung Inflammation and Fibrosis.
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Ginsenoside Rb1 prevents osteoporosis via the AHR/PRELP/NF-κB signaling axis.
Glioma-targeted multifunctional nanoparticles to co-deliver camptothecin and curcumin for enhanced chemo-immunotherapy.
RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.
Gut microbiota-dependent catabolites of tryptophan play a predominant role in the protective effects of turmeric polysaccharides against DSS-induced ulcerative colitis.
Jin T, Yi Q, Wang Y, Liu W, Zheng L, An J, Mi H, Zhou L, Liu F, Wang X
Frontiers in microbiology 2026;17:1764082
Frontiers in microbiology 2026;17:1764082
Aryl hydrocarbon receptor in club cells drives Th17-mediated lung injury following inhalation exposure to environmentally persistent free radicals.
Pathak R, Kumar A, Ferrier A, Burk D, Cormier SA
Redox biology 2026 May;92:104105
Redox biology 2026 May;92:104105
Benzo[a]pyrene exacerbates bone destruction by inhibiting Treg differentiation, impairing Treg function and promoting osteoclastogenesis in rats with collagen-induced arthritis.
Deng T, Wang X, Shi T, Jiao Y, Geng Q, Wang Z, Xiao C
Ecotoxicology and environmental safety 2026 May;316:120135
Ecotoxicology and environmental safety 2026 May;316:120135
Therapeutic potential of Isatidis Radix alkaloids in RSV pneumonia: A focus on AhR-mediated pulmonary barrier repair.
Xu S, Hou X, Xu Y, Wang X, Xu L, He L
Journal of ethnopharmacology 2026 May 10;362:121387
Journal of ethnopharmacology 2026 May 10;362:121387
Ligilactobacillus murinus alleviates binge-eating behavior by restoring serotonin metabolism.
Liao Y, Chen J, Zeng M, Chen Y, Zan B, Yang X, Wang H, Du P, Zhao H
Food research international (Ottawa, Ont.) 2026 May 1;231(Pt 2):118691
Food research international (Ottawa, Ont.) 2026 May 1;231(Pt 2):118691
Proline/serine-rich coiled-coil 1 alleviates atherosclerosis via remodeling tryptophan metabolism mediated by Akkermansia muciniphila.
Wu Q, Hu K, Wang Q, Luo T, Hu L, Liu J, Zou D, Hu J, Guo Z
Experimental & molecular medicine 2026 Mar;58(3):848-863
Experimental & molecular medicine 2026 Mar;58(3):848-863
Asiaticoside protects against PDF-induced peritoneal fibrosis via suppression of AhR/Nrf2-mediated MMT and oxidative stress.
Zhao J, Zhou W, Xue W, Yuan M, Wang M, Cai Z, Ding N
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(6):8215-8228
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(6):8215-8228
Transcriptomic Insights Into Alzheimer's Disease: Differentially Expressed Genes and Cholesterol Metabolism.
Sun R, Wang X, Wang Z, Li C, Shao Q, Liu X, Zhu H, Wang S, He K
CNS neuroscience & therapeutics 2026 Mar;32(3):e70833
CNS neuroscience & therapeutics 2026 Mar;32(3):e70833
Differential Effects of Saturated and Unsaturated Fatty Acids on Colorectal Cancer via IDO1 Signaling.
Zhang S, Zhang J, Chen J, Singab ANB, Yang G, Li J, Li P, Wu S, Zhao D, Sun J, Gao L, Lin G, Yu G, Iv Y, Wang H, Yuan L, Ye L
Cancer medicine 2026 Mar;15(3):e71644
Cancer medicine 2026 Mar;15(3):e71644
Dietary advanced glycation products combined with chronic restraint stress induced anxiety-like and depression-like behaviors in male mice.
Zhang Y, Gu K, Xin L, Xia Y, Yang G, Cai J, He Z, Qin LQ, Wan Z
NPJ science of food 2026 Mar 8;10(1)
NPJ science of food 2026 Mar 8;10(1)
Loganic Acid Ameliorates Rheumatoid Arthritis via the Lactobacillus murinus-Inodole-3-Acetic Acid-AhR-IL-10 Axis.
Tan W, Fu Y, Hu W, Lin Y, Cai J, Huang X, OuYang Y, Lin S, Ye L
Phytotherapy research : PTR 2026 Mar 28;
Phytotherapy research : PTR 2026 Mar 28;
Molecular crosstalk between PPARγ and AhR determines the endocrine-disrupting profile of amiodarone (AMD) in hippocampal neurons.
Szychowski KA, Skóra B
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116061
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116061
The Scutellaria baicalensis-Coptis chinensis herb pair ameliorates ulcerative colitis via integrated modulation of the aryl hydrocarbon receptor/NLRP3 inflammasome axis with tryptophan metabolites.
Fang D, Sheng X, Li X, Tan B, Zhang J, Ding K, Kang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158164
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158164
Zanthoxylum bungeanum essential oil alleviates DSS-induced ulcerative colitis in mice by modulating gut microbiota-dependent AhR/Nrf2 signaling.
Sun L, Xu B, Liang Y, Tao Y, Wei C, Du W, Chen P, Wang L, Yang X, Chen X
Food research international (Ottawa, Ont.) 2026 Jun 1;233(Pt 1):118986
Food research international (Ottawa, Ont.) 2026 Jun 1;233(Pt 1):118986
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Cen Q, Cui Y, Feng J, Zhu L, Wei J, Wang L, Chang C, Pang R, Wang J, Zhang A
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Fangji Huangqi Tang alleviated chronic kidney disease by regulating intestinal bacteria to inhibit the AHR/ROS pathway.
Li A, Ju Z, Zhang X, Wang M, Xing J, Liu G, Qin X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157610
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157610
Gut metabolite indole-3-acetic acid aggravates neuropsychiatric lupus via the AHR/STAT3 pathway in microglia.
Feng Y, Zheng L, Tang W, Wang P, Lai Y, Qin J, Zhou C, Zhang X, Yang M, Jie L, Yu G, Ren H, Huang Q
Communications biology 2026 Jan 23;9(1):281
Communications biology 2026 Jan 23;9(1):281
Differential Toxicity of Water-Soluble Versus Water-Insoluble Components of Cowshed PM2.5 on Ovarian Granulosa Cells and the Regulatory Role of Txnip in Overall Toxicity.
Ma Z, Zhang X, Du X, Zhao C, Jia Y, Wang Y, Li X, Yu X, Gao Y
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Microbiota-driven tryptophan metabolism and AhR triggered intestinal stem cell differentiation: mechanisms of huangqin decoction in ulcerative colitis repair.
Li R, Liao X, Fu X, Li X, Liao X, Cen S, Zeng J, Huang L, Chi H, Zou Y
Chinese medicine 2026 Jan 13;21(1):33
Chinese medicine 2026 Jan 13;21(1):33
Regulating Tumor Metabolic Reprogramming with Biomimetic Co-Delivery of Simvastatin and Kynureninase for Immunotherapy.
Yin J, Yang S, Liu Z, Zhao S, Sun S, Liu Z, Li Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(12):e08107
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(12):e08107
Inducible CD147 up-regulation boosts extended SARS-CoV-2 infection triggering severe COVID-19 independent of ACE2.
Wang K, Lin P, Chen R, Huang Q, Zhao Y, Zhang L, Zhao Y, Zhong L, Xu K, Bao L, Wang Y, Qin C, Wu G, Zhang H, Geng J, Zhang Z, Wei D, Chen X, Tang H, Yang L, Yang X, Sun X, Yao R, Zhao Y, Qin W, Yang Z, Chen L, Bian H, Chen ZN, Zhu P
Signal transduction and targeted therapy 2026 Feb 3;11(1):42
Signal transduction and targeted therapy 2026 Feb 3;11(1):42
Akkermansia muciniphila reduces neuroinflammation and Aβ deposition via tryptophan metabolism in the APP/PS1 mouse model of Alzheimer's disease.
Wang B, Pan M, Yang L, Xu J, Ye C, Li Y, Gong Q, Liu C, Li L, Qin J, Ren D, Zhao C, Liang C
Alzheimer's research & therapy 2026 Feb 19;18(1):41
Alzheimer's research & therapy 2026 Feb 19;18(1):41
Two orthobunyaviruses: OYAV and EBIV co-opt the AhR-CYP1A1 axis to suppress type I interferon responses.
Hu Q, Wang F, Wang X, Li X, Yuan Z, Zhong M, Xia H
Virologica Sinica 2026 Apr 30;
Virologica Sinica 2026 Apr 30;
Lycium Barbarum Polysaccharide Attenuates Staphylococcus aureus-Induced Mastitis via the Gut Microbiota-Derived Indole-3-Propionic Acid/AhR-IL-22-STAT3 Axis.
Li K, Ran X, Ding H, Han J, Zhang L, Wang X, Guo W, Li Y, Fu S, Bi J
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12038-12053
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12038-12053
Lactobacillus paracasei ZJUZ2-3 inhibits gastrointestinal tumors via the IAA-induced AHR/MTDH/NF-κB axis.
Yang R, Yang Y, Wu L, He K, Bi D, Teng L
International journal of biological sciences 2025;21(14):6522-6541
International journal of biological sciences 2025;21(14):6522-6541
Huangkui capsules regulate tryptophan metabolism to improve diabetic nephropathy through the Keap1/Nrf2/HO-1 pathway.
Su J, Zhang Y, Wang X, Hu X, Zhou K, Zhu H, Liu E, Liu S
Frontiers in pharmacology 2025;16:1535352
Frontiers in pharmacology 2025;16:1535352
GPX4 knockdown suppresses M2 macrophage polarization in gastric cancer by modulating kynurenine metabolism.
Xu J, Weng C, Zhang Y, Zhao Q, Chen J, Pan S, Wang Y, Zhang R, Wang Y, Zhu W, Cao M, Zu D, Zhang S, Xu Z, Hu C, Cheng X
Theranostics 2025;15(12):5826-5845
Theranostics 2025;15(12):5826-5845
Hydrogen regulates the aryl hydrocarbon receptor, improving bronchopulmonary dysplasia in neonatal rats and RLE-6TN cells exposed to hyperoxia.
Liang M, Song F, Wang J, Yang C, Yin H, Zhou W
Frontiers in pediatrics 2025;13:1662922
Frontiers in pediatrics 2025;13:1662922
Methionine ameliorates intestinal injury in senescence-accelerated mouse prone-8 mice by reducing sulfate-reducing bacteria and enhancing barrier function.
Wu Y, Zhang Y, Zhou M, Liu P, Rao X, Zhang Y, Mi M
Frontiers in nutrition 2025;12:1698518
Frontiers in nutrition 2025;12:1698518
Quercetin ameliorates obesity and inflammation via microbial metabolite indole-3-propionic acid in high fat diet-induced obese mice.
Lu J, Huang Y, Zhang Y, Xie J, Guo Q, Yang H, Yang Y, Chen J, Su L
Frontiers in nutrition 2025;12:1574792
Frontiers in nutrition 2025;12:1574792
Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis.
Wang L, Lv W, Mao H, Chen Q, Ma Y, Zhang L, Ruan Y, Zhang C
Free radical biology & medicine 2025 Sep;237:251-269
Free radical biology & medicine 2025 Sep;237:251-269
A Preliminary Study of the Relationship Between Zinc and the AhR Signaling Pathway During Palatal Development.
Liang S, Zhai Y, Chen Z, Yang J, Shu X, Luo J, Wang N, Wang F, Song Q
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2025 Sep 8;:10556656251375952
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2025 Sep 8;:10556656251375952
Long-term low-dose exposure to 9-chlorophenanthrene induces liver lipid accumulation via disrupting circadian rhythm.
Liu M, Lu Y, Zhou H, Chen Y, Li Y, Zhang T
Journal of hazardous materials 2025 Sep 5;495:139145
Journal of hazardous materials 2025 Sep 5;495:139145
Bifidobacterium longum subsp. longum B-53 Alleviated Abnormalities of Glycolipid Metabolism and Oxidative Stress in T2DM Mice Through Regulating Gut Microbiota and GLP-1 Secretion.
Chen J, Zhang L, Cheng Z, Zhang Y, Li X, Zheng S, Zhang N, Li B, Liu F, Jiao Y
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24169-24186
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24169-24186
Aryl Hydrocarbon Receptor (AhR)-Independent Amiodarone (AMD) Toxicity in HepG2 Cell Line.
Szychowski KA, Skóra B, Piechowiak T, Szlachcikowska D
Journal of applied toxicology : JAT 2025 Nov;45(11):2305-2320
Journal of applied toxicology : JAT 2025 Nov;45(11):2305-2320
Targeting Tris(2,3-dibromopropyl) Isocyanurate-Induced Inflammation in Hippocampal Neurons In Vitro: Mechanistic Insights and Implications for Neurodegenerative Disease Prevention.
Szlachcikowska D, Koszła O, Sołek P, Tabęcka-Łonczyńska A
Molecular neurobiology 2025 Nov 19;63(1):84
Molecular neurobiology 2025 Nov 19;63(1):84
Quercetin protected the gut barrier in ulcerative colitis by activating aryl hydrocarbon receptor.
Wei Q, Jiang H, Zeng J, Xu J, Zhang H, Xiao E, Lu Q, Huang G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156633
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156633
Carboxychalcones Based on Terephthalaldehydic Acid as Potential Neuroprotective Agents. Synthesis, Computational Study and Biological Evaluation.
Olender D, Skóra B, Kasprzak M, Kujawski J, Sowa-Kasprzak K, Pawełczyk A, Muszalska-Kolos I, Szychowski KA
ACS omega 2025 May 20;10(19):19860-19872
ACS omega 2025 May 20;10(19):19860-19872
Evaluating the Effects of Neburon Exposure on Ovarian Folliculogenesis Using Zebrafish and Mouse Granulosa Cell Line.
Tang C, Zhang Y, Zhang F, Sun Y, Zhu Y, Xue F, Wang Z, Wu Y, Ruan J, Yue Y, Yang C, Ge W, He C, Zuo Z
Environmental health perspectives 2025 May 15;
Environmental health perspectives 2025 May 15;
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
Qiao CM, Ma XY, Tan LL, Xia YM, Li T, Wu J, Cui C, Zhao WJ, Shen YQ
Experimental neurology 2025 Mar;385:115142
Experimental neurology 2025 Mar;385:115142
IDO1 inhibitors block septic cytokine storm by suppressing the IDO1-AHR-CYP1A1 axis.
Chen Y, Ying J, Li Z, He ZNT, Zhan J, Liang H, Liu Y, Chen Y, Li X, Zhu T, Kuang C, Lu G, Yang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jun;187:118054
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jun;187:118054
Exposure to the prenatal enriched environment alters maternal gut microbiota and promotes embryonic neurodevelopment via activating the AHR-Src pathway.
Liu Y, Huang C, Cheng X, Qu W, Wang X, Liu S, Zhang J, Li Y, Huang X, Zhu J, Ma D, Shu Q, Li X
Science China. Life sciences 2025 Jul;68(7):1964-1979
Science China. Life sciences 2025 Jul;68(7):1964-1979
Multi-omics study reveals gut microbiota dysbiosis and tryptophan metabolism alterations in GH-PitNET progression.
Liu J, Ye Z, Zhang Y, You S, Sun S, Lu L, Su W, Liu J, Pu J, Pan H, Zhu H, Deng K, Yao Y, Hu X, Zhang S
Scientific reports 2025 Jul 7;15(1):24261
Scientific reports 2025 Jul 7;15(1):24261
Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line.
Szychowski KA, Skóra B, Kosińska K, Szlachcikowska D
Biochemical and biophysical research communications 2025 Jul 30;772:152059
Biochemical and biophysical research communications 2025 Jul 30;772:152059
Gut microbiota-derived indole-3-acetic acid ameliorates calcium oxalate renal stone formation via AHR/NF‑κB axis.
Jing J, Yan X, Wang L, Zhang Y, Qi W, Xi J, Hao Z
Urolithiasis 2025 Jul 2;53(1):134
Urolithiasis 2025 Jul 2;53(1):134
SLC7A5 regulates tryptophan uptake and PD‑L1 expression levels via the kynurenine pathway in ovarian cancer.
Jiang R, Jin B, Sun Y, Chen Z, Wan D, Feng J, Ying L, Peng C, Gu L
Oncology letters 2025 Jan;29(1):26
Oncology letters 2025 Jan;29(1):26
Cigarette smoke-induced attenuation of the prostaglandin transporter SLCO2A1 expression through aryl hydrocarbon receptor.
Shumba MN, Nakamura Y, Nakanishi T
Prostaglandins & other lipid mediators 2025 Jan;176:106935
Prostaglandins & other lipid mediators 2025 Jan;176:106935
Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway.
Duah M, Zheng F, Shen J, Xu Y, Cao S, Yan Z, Lan Q, Wang Y, Xu K, Pan B
Acta pharmaceutica Sinica. B 2025 Jan;15(1):224-238
Acta pharmaceutica Sinica. B 2025 Jan;15(1):224-238
Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice.
Wang XM, Qin CM, Li D, Xu XR, Pan XJ, Xue H
Ecotoxicology and environmental safety 2025 Jan 15;290:117743
Ecotoxicology and environmental safety 2025 Jan 15;290:117743
Engagement of peroxisome proliferator-activated receptor gamma (PPARγ) and mammalian target of rapamycin (mTOR) in the triclosan-induced disruption of Cyp450 enzyme activity in an in vitro model of mouse embryo fibroblasts (3T3-L1).
Szychowski KA, Skóra B, Wójtowicz AK
Toxicology 2025 Feb;511:154031
Toxicology 2025 Feb;511:154031
Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis.
Ma C, Han L, Zhao W, Chen F, Huang R, Pang CH, Zhu Z, Pan G
Biochemical pharmacology 2025 Feb;232:116711
Biochemical pharmacology 2025 Feb;232:116711
Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea.
Lin Z, Feng Y, Wang J, Men Z, Ma X
Microbiome 2025 Feb 4;13(1):36
Microbiome 2025 Feb 4;13(1):36
The aryl hydrocarbon receptor affects the inflammatory response of bone marrow mesenchymal stem cell via the hippo-YAP pathway to exacerbate systemic lupus erythematosus.
Yang X, Si M, Liu T, Yang J, Jiang L, Sun X, Yu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 28;39(4):e70410
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 28;39(4):e70410
Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells.
Tabęcka-Łonczyńska A, Skóra B, Szlachcikowska D, Jastrząb R, Marć MA, Mytych J, Koszła O, Sołek P, Szychowski KA
Pharmacological reports : PR 2025 Dec;77(6):1557-1572
Pharmacological reports : PR 2025 Dec;77(6):1557-1572
Tryptophan derivatives as non-invasive diagnostic indicators for obesity-related MASLD in children and adolescents.
Zhan S, Wang X, Wang C, Zhu B, Gao J, Peng Z, Wang R, Yang Y, Zhang L, Wang T, Wu J, Wu W, Huang K, Dong G, Ren Q, Wang S, Wang S, Zhou X, Xu L, Fu J, Guo X
Diabetes, obesity & metabolism 2025 Dec;27(12):7544-7560
Diabetes, obesity & metabolism 2025 Dec;27(12):7544-7560
Aldehyde dehydrogenase ALDH3A1 rescues cigarette smoke-induced emphysema by conferring alveolar type 2 to type 1 cell transition.
Cui J, Han S, Li J, Li X, Liang L
Free radical biology & medicine 2025 Dec 16;241:511-525
Free radical biology & medicine 2025 Dec 16;241:511-525
Role of indoleamine 2,3-Dioxygenase 1 in modulating the malignant biological behavior of cervical cancer cells through the Tryptophan-Kynurenine pathway.
Zhang S, Wang L, Xu SY, Zhang YY, Li KX, Wang L, Chen Y, Chen Q
Journal of molecular histology 2025 Aug 22;56(5):276
Journal of molecular histology 2025 Aug 22;56(5):276
Hypoxia-induced PRMT1 methylates HIF2β to promote breast tumorigenesis via enhancing glycolytic gene transcription.
Li WJ, Chen YC, Lin YA, Zou YQ, Hu GS, Yang JJ, Nie XY, Li MY, Wang YR, He YH, Zhao Y, Tan YH, Deng X, He WL, Cheng Y, Fu FM, Liu W
Cell reports 2025 Apr 22;44(4):115487
Cell reports 2025 Apr 22;44(4):115487
Spermidine attenuates chondrocyte inflammation and cellular pyroptosis through the AhR/NF-κB axis and the NLRP3/caspase-1/GSDMD pathway.
Guo X, Feng X, Yang Y, Zhang H, Bai L
Frontiers in immunology 2024;15:1462777
Frontiers in immunology 2024;15:1462777
Baitouweng decoction alleviates ulcerative colitis by regulating tryptophan metabolism through DOPA decarboxylase promotion.
Zhang J, Lin B, Zhang Y, Hu X, Liu T, Liu EH, Liu S
Frontiers in pharmacology 2024;15:1423307
Frontiers in pharmacology 2024;15:1423307
Targeting mitochondrial dysfunction in atopic dermatitis with trilinolein: A triacylglycerol from the medicinal plant Cannabis fructus.
Wang Y, Lu H, Cheng L, Guo W, Hu Y, Du X, Liu X, Xu M, Liu Y, Zhang Y, Xi R, Wang P, Liu X, Duan Y, Zhu J, Li F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155856
Microbial Tryptophan Metabolites Ameliorate Ovariectomy-Induced Bone Loss by Repairing Intestinal AhR-Mediated Gut-Bone Signaling Pathway.
Chen C, Cao Z, Lei H, Zhang C, Wu M, Huang S, Li X, Xie D, Liu M, Zhang L, Chen G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2404545
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2404545
Multi-omics insights into anti-colitis benefits of the synbiotic and postbiotic derived from wheat bran arabinoxylan and Limosilactobacillus reuteri.
Zhou L, Song W, Liu T, Yan T, He Z, He W, Lv J, Zhang S, Dai X, Yuan L, Shi L
International journal of biological macromolecules 2024 Oct;278(Pt 3):134860
International journal of biological macromolecules 2024 Oct;278(Pt 3):134860
Elastin-derived peptides (EDPs) affect gene and protein expression in human mesenchymal stem cells (hMSCs) - preliminary study.
Szychowski KA, Skóra B
Cytokine 2024 Oct;182:156725
Cytokine 2024 Oct;182:156725
IDO1 inhibitors are synergistic with CXCL10 agonists in inhibiting colon cancer growth.
Yang M, Cao M, Zhang X, Fu B, Chen Y, Tan Y, Xuan C, Su Y, Tan D, Hu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117412
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117412
Tumor-colonized Streptococcus mutans metabolically reprograms tumor microenvironment and promotes oral squamous cell carcinoma.
Zhou J, Hu Z, Wang L, Hu Q, Chen Z, Lin T, Zhou R, Cai Y, Wu Z, Zhang Z, Yang Y, Zhang C, Li G, Zeng L, Su K, Li H, Su Q, Zeng G, Cheng B, Wu T
Microbiome 2024 Oct 5;12(1):193
Microbiome 2024 Oct 5;12(1):193
Low-Medium Polarity Ginsenosides from Wild Ginseng Improves Immunity by Activating the AhR/MAPK Pathway through Tryptophan Metabolism Driven by Gut Microbiota.
Zhang M, Ma L, Luo J, Ren T, Liu S, Pan L, Bao Y, Li F, Dai Y, Pi Z, Yue H, Zheng F
Journal of agricultural and food chemistry 2024 Nov 27;72(47):26142-26154
Journal of agricultural and food chemistry 2024 Nov 27;72(47):26142-26154
StemRegenin 1 attenuates the RANKL-induced osteoclastogenesis via inhibiting AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway.
Zhou S, Li J, Ying T, Wang Y, Wang Q, Li X, Zhao F
iScience 2024 May 17;27(5):109682
iScience 2024 May 17;27(5):109682
Roles of AhR/CYP1s signaling pathway mediated ROS production in uremic cardiomyopathy.
Lu W, Cheng S, Xu J, Xiao Z, Yu Y, Xie Q, Fang Y, Chen R, Shen B, Xie Y, Ding X
Toxicology letters 2024 May 15;396:81-93
Toxicology letters 2024 May 15;396:81-93
Metabolic landscape of head and neck squamous cell carcinoma informs a novel kynurenine/Siglec-15 axis in immune escape.
Zhang XY, Shi JB, Jin SF, Wang RJ, Li MY, Zhang ZY, Yang X, Ma HL
Cancer communications (London, England) 2024 Jun;44(6):670-694
Cancer communications (London, England) 2024 Jun;44(6):670-694
Role of 4-Thiazolidinone-Pyrazoline/Indoline Hybrids Les-4369 and Les-3467 in BJ and A549 Cell Lines.
Kosińska K, Skóra B, Holota S, Shepeta Y, Tabęcka-Łonczyńska A, Lesyk R, Szychowski KA
Cells 2024 Jun 8;13(12)
Cells 2024 Jun 8;13(12)
Activation of aryl hydrocarbon receptor (AhR) alleviates depressive-like behaviors in LPS-induced mice.
Wang MY, Li JM, Wu YL, Zhang Y, Hu T, Su WJ, Feng JF, Jiang CL
Sheng li xue bao : [Acta physiologica Sinica] 2024 Jun 25;76(3):353-364
Sheng li xue bao : [Acta physiologica Sinica] 2024 Jun 25;76(3):353-364
Multi-omics approaches for the understanding of therapeutic mechanism for Huang-Qi-Long-Dan Granule against ischemic stroke.
Wu C, Wu C, Peng L, Wu M, Li Z, Chen J
Pharmacological research 2024 Jul;205:107229
Pharmacological research 2024 Jul;205:107229
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Wang X, Xie X, Li Y, Xie X, Huang S, Pan S, Zou Y, Pan Z, Wang Q, Chen J, Zhou L, Luo X
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Microbiota-derived I3A protects the intestine against radiation injury by activating AhR/IL-10/Wnt signaling and enhancing the abundance of probiotics.
Xie LW, Cai S, Lu HY, Tang FL, Zhu RQ, Tian Y, Li M
Gut microbes 2024 Jan-Dec;16(1):2347722
Gut microbes 2024 Jan-Dec;16(1):2347722
Intracellular tacrolimus concentration correlates with impaired renal function through regulation of the IS-AHR-ABC transporter in peripheral blood mononuclear cells.
Guo P, Zhang R, Zhou J, Li P, Liu Y, Shi S
International immunopharmacology 2024 Jan 5;126:111233
International immunopharmacology 2024 Jan 5;126:111233
Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy.
Li Z, Li S, Xing Z, Gu Q, Du R, Jiang J, Yuan X, Zhang X, Chen X, Xue N, Zhang P, Jin J, Yang Y
Journal of medicinal chemistry 2024 Jan 25;67(2):1243-1261
Journal of medicinal chemistry 2024 Jan 25;67(2):1243-1261
Hesperetin protects hippocampal neurons from the neurotoxicity of Aflatoxin B1 in mice.
Song C, Wang Z, Cao J, Dong Y, Chen Y
Ecotoxicology and environmental safety 2024 Jan 1;269:115782
Ecotoxicology and environmental safety 2024 Jan 1;269:115782
Aucubin ameliorates atherosclerosis by modulating tryptophan metabolism and inhibiting endothelial-mesenchymal transitions via gut microbiota regulation.
Luo Z, Yang L, Zhu T, Fan F, Wang X, Liu Y, Zhan H, Luo D, Guo J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156122
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156122
Cannabidiol Suppresses Metastatic Castration-Resistant Prostate Cancer Progression and Recurrence through Modulating Tryptophan Catabolism.
Mudhish EA, Ebrahim HY, Helal IE, Alhowiriny AT, El Sayed KA
ACS pharmacology & translational science 2024 Dec 13;7(12):3902-3913
ACS pharmacology & translational science 2024 Dec 13;7(12):3902-3913
Identification of potential key lipid metabolism-related genes involved in tubular injury in diabetic kidney disease by bioinformatics analysis.
Fan Y, He J, Shi L, Zhang M, Chen Y, Xu L, Han N, Jiang Y
Acta diabetologica 2024 Aug;61(8):1053-1068
Acta diabetologica 2024 Aug;61(8):1053-1068
CDKs Functional Analysis in Low Proliferating Early-Stage Pancreatic Ductal Adenocarcinoma.
Zhu S, Yang H, Liu L, Jiang Z, Ji J, Wang X, Zhong L, Liu F, Gao X, Wang H, Zhou Y
Journal of bioinformatics and systems biology : Open access 2023;6(3):187-200
Journal of bioinformatics and systems biology : Open access 2023;6(3):187-200
Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis.
Song H, Kim EH, Hong J, Gwon D, Kim JW, Bae GU, Jang CY
Cell death and differentiation 2023 Sep;30(9):2151-2166
Cell death and differentiation 2023 Sep;30(9):2151-2166
Pyrrolidinedione-thiazolidinone hybrid molecules with potent cytotoxic effect in squamous cell carcinoma SCC-15 cells.
Finiuk N, Kaleniuk E, Holota S, Stoika R, Lesyk R, Szychowski KA
Bioorganic & medicinal chemistry 2023 Sep 7;92:117442
Bioorganic & medicinal chemistry 2023 Sep 7;92:117442
CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis.
Zhang H, Deng Z, Wang Y, Zheng X, Zhou L, Yan S, Wang Y, Dai Y, Kanwar YS, Deng F
iScience 2023 Oct 20;26(10):107762
iScience 2023 Oct 20;26(10):107762
Involvement of estrogen receptor alpha (ERα) and impairment of steroidogenesis after exposure to tris(2,3-dibromopropyl) isocyanurate (TBC) in mouse spermatogenic (GC-1 spg) cells in vitro.
Tabęcka-Łonczyńska A, Kaczka P, Kaleniuk E
The Journal of steroid biochemistry and molecular biology 2023 Nov;234:106398
The Journal of steroid biochemistry and molecular biology 2023 Nov;234:106398
Knockdown of IL4I1 Improved High Glucose-evoked Insulin Resistance in HepG2 Cells by Alleviating Inflammation and Lipotoxicity Through AHR Activation.
Run L, Tian Z, Xu L, Du J, Li N, Wang Q, Sun H
Applied biochemistry and biotechnology 2023 Nov;195(11):6694-6707
Applied biochemistry and biotechnology 2023 Nov;195(11):6694-6707
Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration.
Shen J, Wang Y, Zheng F, Cao S, Lan Q, Xu K, Pan B
NPJ Regenerative medicine 2023 Nov 8;8(1):64
NPJ Regenerative medicine 2023 Nov 8;8(1):64
Gut microbiota-derived 3-phenylpropionic acid promotes intestinal epithelial barrier function via AhR signaling.
Hu J, Chen J, Xu X, Hou Q, Ren J, Yan X
Microbiome 2023 May 8;11(1):102
Microbiome 2023 May 8;11(1):102
Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism.
Xu H, Hu C, Wang Y, Shi Y, Yuan L, Xu J, Zhang Y, Chen J, Wei Q, Qin J, Xu Z, Cheng X
Oncogene 2023 Jun;42(24):1994-2006
Oncogene 2023 Jun;42(24):1994-2006
Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis.
Zhuang H, Ren X, Jiang F, Zhou P
Molecular medicine (Cambridge, Mass.) 2023 Jan 31;29(1):17
Molecular medicine (Cambridge, Mass.) 2023 Jan 31;29(1):17
Crosstalk between the aryl hydrocarbon receptor (AhR) and the peroxisome proliferator-activated receptor gamma (PPARγ) as a key factor in the metabolism of silver nanoparticles in neuroblastoma (SH-SY5Y) cells in vitro.
Skóra B, Matuszewska P, Masicz M, Sikora K, Słomczewska M, Sołtysek P, Szychowski KA
Toxicology and applied pharmacology 2023 Jan 1;458:116339
Toxicology and applied pharmacology 2023 Jan 1;458:116339
Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma.
Xu M, Zhu F, Yin Q, Yin H, Fang S, Luo G, Huang J, Huang W, Liu F, Zhong M, Deng X
Cancers 2023 Feb 19;15(4)
Cancers 2023 Feb 19;15(4)
Assessment of intestinal status in MPL(W515L) mutant myeloproliferative neoplasms mice model.
Zhu S, Xu K, Li S, Yu X, Liu Y, Zhang Q, Zeng L, Xu K, Fu C
International immunopharmacology 2023 Dec;125(Pt A):111091
International immunopharmacology 2023 Dec;125(Pt A):111091
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM(2.5)-induced lung injury: a comparative study.
Chen S, Li M, Zhang R, Ye L, Jiang Y, Jiang X, Peng H, Wang Z, Guo Z, Chen L, Zhang R, Niu Y, Aschner M, Li D, Chen W
Particle and fibre toxicology 2023 Apr 17;20(1):10
Particle and fibre toxicology 2023 Apr 17;20(1):10
MBL Binding with AhR Controls Th17 Immunity in Silicosis-Associated Lung Inflammation and Fibrosis.
Liu Y, Zhao N, Xu Q, Deng F, Wang P, Dong L, Lu X, Xia L, Wang M, Chen Z, Zhou J, Zuo D
Journal of inflammation research 2022;15:4315-4329
Journal of inflammation research 2022;15:4315-4329
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Wang Z, Yin L, Qi Y, Zhang J, Zhu H, Tang J
Frontiers in microbiology 2022;13:934786
Frontiers in microbiology 2022;13:934786
Ginsenoside Rb1 prevents osteoporosis via the AHR/PRELP/NF-κB signaling axis.
Zhang D, Du J, Yu M, Suo L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154205
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154205
Glioma-targeted multifunctional nanoparticles to co-deliver camptothecin and curcumin for enhanced chemo-immunotherapy.
Wang Z, Wang X, Yu H, Chen M
Biomaterials science 2022 Mar 2;10(5):1292-1303
Biomaterials science 2022 Mar 2;10(5):1292-1303
RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.
Yu J, Qi H, Wang Z, Zhang Z, Song E, Song W, An R
Cell biology international 2022 Dec;46(12):2246-2256
Cell biology international 2022 Dec;46(12):2246-2256
Gut microbiota-dependent catabolites of tryptophan play a predominant role in the protective effects of turmeric polysaccharides against DSS-induced ulcerative colitis.
Yang C, Du Y, Ren D, Yang X, Zhao Y
Food & function 2021 Oct 19;12(20):9793-9807
Food & function 2021 Oct 19;12(20):9793-9807
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