Antibody data
- Antibody Data
- Antigen structure
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- Product number
- FNab00231 - Provider product page
- Provider
- FineTest Biotech
- Product name
- AHR antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
aryl hydrocarbon receptor
- Epitope
- IgG
- Isotype
- IgG
- Vial size
- 100¦Ìg
- Concentration
- Immunogen affinity purified
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
- Handling
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
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