Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10922-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10922-1-AP, RRID:AB_2221854
- Product name
- ARP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ARP2 antibody (Cat. #10922-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references YAP/TAZ-mediated nuclear membrane rupture in promoting senescence of skeletal muscle associated with COPD.
Mechanisms of CRLF3-targeted binding to ACTR2 to promote hepatocellular carcinoma progression and effects on the immune microenvironment.
Activation of mannose receptor C type 1 in macrophages improves renal fibrosis through mediating fibronectin endocytosis.
Microfilament-Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice.
Sulforaphane suppresses bladder cancer metastasis via blocking actin nucleation-mediated pseudopodia formation.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
EMT induces characteristic changes of Rho GTPases and downstream effectors with a mitosis-specific twist.
Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein.
Interaction of species A rotavirus VP4 with the cellular proteins vimentin and actin related protein 2 discovered by a proximity interactome assay.
FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms.
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.
SKAP2 is downregulated in the villous tissues of patients with missed abortion and regulates growth and migration in trophoblasts through the WAVE2-ARP2/3 signaling pathway.
G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities.
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex.
Inhibition of N-WASP affects actin-mediated cytokinesis during porcine oocyte maturation.
RAB8A GTPase regulates spindle migration and Golgi apparatus distribution via ROCK-mediated actin assembly in mouse oocyte meiosis†.
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.
Decreased expression of cortactin in the schizophrenia brain.
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
Gong G, Shen S, Shen S, Wang R, Zheng T, Xu W, Wu J
Respiratory research 2025 Mar 12;26(1):98
Respiratory research 2025 Mar 12;26(1):98
Mechanisms of CRLF3-targeted binding to ACTR2 to promote hepatocellular carcinoma progression and effects on the immune microenvironment.
Ye S, Zhang X, Liu F, Niu Q, Liu A, Xia D
Cytotechnology 2025 Jun;77(3):113
Cytotechnology 2025 Jun;77(3):113
Activation of mannose receptor C type 1 in macrophages improves renal fibrosis through mediating fibronectin endocytosis.
Long L, Li M, Wang M, Liang B, Huang M, Yuan X, Wu X, Guo X, Li S, Liu Z, Liu W, Chen W, Wang W, Lyu Q, Li C
Life sciences 2025 Jun 15;371:123593
Life sciences 2025 Jun 15;371:123593
Microfilament-Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice.
Xu R, Pan M, Zheng Z, Tang Y, Yan Y, Lu S, Peng S, Ma B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e00358
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e00358
Sulforaphane suppresses bladder cancer metastasis via blocking actin nucleation-mediated pseudopodia formation.
Huang L, Wang J, Wang X, Zheng S, Liang K, Kang YE, Chang JW, Koo BS, Liu L, Gal A, Shan Y
Cancer letters 2024 Oct 1;601:217145
Cancer letters 2024 Oct 1;601:217145
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
EMT induces characteristic changes of Rho GTPases and downstream effectors with a mitosis-specific twist.
Hosseini K, Frenzel A, Fischer-Friedrich E
Physical biology 2023 Sep 12;20(6)
Physical biology 2023 Sep 12;20(6)
Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein.
Zhang C, Schekman R
eLife 2023 Mar 10;12
eLife 2023 Mar 10;12
Interaction of species A rotavirus VP4 with the cellular proteins vimentin and actin related protein 2 discovered by a proximity interactome assay.
Hao P, Qu Q, Pang Z, Li L, Du S, Shang L, Jin C, Xu W, Ha Z, Jiang Y, Chen J, Gao Z, Jin N, Wang J, Li C
Journal of virology 2023 Dec 21;97(12):e0137623
Journal of virology 2023 Dec 21;97(12):e0137623
FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms.
St Paul A, Corbett C, Peluzzo A, Kelemen S, Okune R, Haines DS, Preston K, Eguchi S, Autieri MV
Cell reports 2023 Apr 25;42(4):112381
Cell reports 2023 Apr 25;42(4):112381
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.
Wang Y, Ma L, Jia S, Liu D, Gu H, Wei X, Ma W, Luo W, Bai Y, Wang W, Yuan Z
Journal of molecular medicine (Berlin, Germany) 2022 Sep;100(9):1307-1319
Journal of molecular medicine (Berlin, Germany) 2022 Sep;100(9):1307-1319
SKAP2 is downregulated in the villous tissues of patients with missed abortion and regulates growth and migration in trophoblasts through the WAVE2-ARP2/3 signaling pathway.
Jin X, Chen Y, Sheng Z, Wang X, Zhang Z, Huang J, Zhou J, Lin F
Placenta 2022 Oct;128:100-111
Placenta 2022 Oct;128:100-111
G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities.
He X, Yuan J, Wang Y
Nucleic acids research 2021 Nov 8;49(19):11323-11336
Nucleic acids research 2021 Nov 8;49(19):11323-11336
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J
eLife 2021 Nov 19;10
eLife 2021 Nov 19;10
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex.
Andrews MG, Subramanian L, Kriegstein AR
eLife 2020 Sep 2;9
eLife 2020 Sep 2;9
Inhibition of N-WASP affects actin-mediated cytokinesis during porcine oocyte maturation.
Wang QC, Wan X, Jia RX, Xu Y, Liu X, Zhang Y, Sun SC
Theriogenology 2020 Mar 1;144:132-138
Theriogenology 2020 Mar 1;144:132-138
RAB8A GTPase regulates spindle migration and Golgi apparatus distribution via ROCK-mediated actin assembly in mouse oocyte meiosis†.
Pan ZN, Lu Y, Tang F, Pan MH, Wan X, Lan M, Zhang Y, Sun SC
Biology of reproduction 2019 Mar 1;100(3):711-720
Biology of reproduction 2019 Mar 1;100(3):711-720
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.
Jayatilaka H, Tyle P, Chen JJ, Kwak M, Ju J, Kim HJ, Lee JSH, Wu PH, Gilkes DM, Fan R, Wirtz D
Nature communications 2017 May 26;8:15584
Nature communications 2017 May 26;8:15584
Decreased expression of cortactin in the schizophrenia brain.
Bhambhvani HP, Simmons M, Haroutunian V, Meador-Woodruff JH
Neuroreport 2016 Feb 10;27(3):145-50
Neuroreport 2016 Feb 10;27(3):145-50
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
Cao J, Shen Y, Zhu L, Xu Y, Zhou Y, Wu Z, Li Y, Yan X, Zhu X
Nature cell biology 2012 Jun 10;14(7):697-706
Nature cell biology 2012 Jun 10;14(7):697-706
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10922-1-AP(ACTR2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The ARP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ARP2. This antibody recognizes human,mouse,rat antigen. The ARP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.