Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [3]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN395370 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ARP3 Actin-Related Protein 3 Homolog (Yeast) (ACTR3) (AA 1-419) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-419
- Isotype
- IgG
- Antibody clone number
- 2B6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branch stability.
The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility.
Host cell entry by apicomplexa parasites requires actin polymerization in the host cell.
Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity.
WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2.
Goley ED, Rammohan A, Znameroski EA, Firat-Karalar EN, Sept D, Welch MD
Proceedings of the National Academy of Sciences of the United States of America 2010 May 4;107(18):8159-64
Proceedings of the National Academy of Sciences of the United States of America 2010 May 4;107(18):8159-64
The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility.
Weisswange I, Newsome TP, Schleich S, Way M
Nature 2009 Mar 5;458(7234):87-91
Nature 2009 Mar 5;458(7234):87-91
Host cell entry by apicomplexa parasites requires actin polymerization in the host cell.
Gonzalez V, Combe A, David V, Malmquist NA, Delorme V, Leroy C, Blazquez S, Ménard R, Tardieux I
Cell host & microbe 2009 Mar 19;5(3):259-72
Cell host & microbe 2009 Mar 19;5(3):259-72
Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity.
Butler B, Cooper JA
Current biology : CB 2009 Dec 1;19(22):1886-96
Current biology : CB 2009 Dec 1;19(22):1886-96
WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2.
Beli P, Mascheroni D, Xu D, Innocenti M
Nature cell biology 2008 Jul;10(7):849-57
Nature cell biology 2008 Jul;10(7):849-57
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Supportive validation
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- Experimental details
- WB
- Submitted by
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
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- Experimental details
- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC