Antibody data
- Antibody Data
- Antigen structure
- References [62]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11071-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11071-1-AP, RRID:AB_2066528
- Product name
- CA9 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CA9 antibody (Cat. #11071-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references AURKA Activates FOXO3a to Form a Positive Feedback Loop in the Proliferation and Migration of Keloid Fibroblasts.
Nitroimidazole-Containing [(68)Ga]Ga-IPM-N001 as a New CAIX-Targeting Radionuclide Tracer.
PDGFRα governs multiple cellular signals and plays a protective role in tumor progression.
CA9+ cancer-associated fibroblasts cooperate with SPP1+ tumor-associated macrophages driving immune resistance in triple-negative breast cancer.
Mechanisms underlying the therapeutic effects of Amygdalin in treating Cervical Cancer based on multi-omics analysis.
Understanding Glioblastoma Dynamics Using 3D Organoids and Engineered Extracellular Matrix.
Identification and validation of icaritin-associated prognostic genes in hepatocellular carcinoma through network pharmacology, bioinformatics analysis, and cellular experiments.
Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcinoma.
Understanding proneural-mesenchymal transition using patient-derived glioma stem-like cell (GSC) organoids and engineered extracellular matrix.
Targeting PLOD2 induces epithelioid differentiation and improves therapeutic response in sarcomatoid renal cell carcinoma.
Comprehensive pan-cancer analysis reveals CD70 as a promising therapeutic target and biomarker in clear cell renal cell carcinoma.
The Diagnostic Value of Plasma Small Extracellular Vesicle-Derived CAIX Protein in Prostate Cancer and Clinically Significant Prostate Cancer: A Study on Predictive Models.
Hypoxia upregulates the expression of PD-L1 via NPM1 in breast cancer.
(124)I-labelled BMSC-Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP-Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis.
Co-immunization with IFI35 enhances the therapeutic effect of an adenovirus vaccine against renal carcinoma.
Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4(QTY)-Fc as a molecular trap.
Epigenetic Regulation of Carbonic Anhydrase 9 Expression by Nitric Oxide in Human Small Airway Epithelial Cells.
Using Multi-Omics Analysis to Explore Diagnostic Tool and Optimize Drug Therapy Selection for Patients with Glioma Based on Cross-Talk Gene Signature.
Enhanced glycolysis causes extracellular acidification and activates acid-sensing ion channel 1a in hypoxic pulmonary hypertension.
A carbonic anhydrase-targeted NIR-II fluorescent cisplatin theranostic nanoparticle for combined therapy of pancreatic tumors.
Comprehensive investigation of malignant epithelial cell-related genes in clear cell renal cell carcinoma: development of a prognostic signature and exploration of tumor microenvironment interactions.
GSH/pH Dual Activatable Cross-linked and Fluorinated PEI for Cancer Gene Therapy Through Endogenous Iron De-Hijacking and in Situ ROS Amplification.
Glucagon Enhances Chemotherapy Efficacy By Inhibition of Tumor Vessels in Colorectal Cancer.
Phytosesquiterpene lactones deregulate mitochondrial activity and phenotypes associated with triple-negative breast cancer metastasis.
Schisandrin C inhibits AKT1-regulated cell proliferation in A549 cells.
Pathway-based stratification of gliomas uncovers four subtypes with different TME characteristics and prognosis.
Carbonic Anhydrase IX Controls Vulnerability to Ferroptosis in Gefitinib-Resistant Lung Cancer.
Arenobufagin increases the sensitivity of gastric cancer to cisplatin via alkaliptosis.
Para-toluenesulfonamide, a novel potent carbonic anhydrase inhibitor, improves hypoxia-induced metastatic breast cancer cell viability and prevents resistance to αPD-1 therapy in triple-negative breast cancer.
KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma.
Effect of isorhamnetin on carbonic anhydrase IX expression and tumorigenesis of bladder cancer by activating PPARγ/PTEN/AKT pathway.
Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis.
Targeting Tumor Hypoxia Inhibits Aggressive Phenotype of Dedifferentiated Thyroid Cancer.
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Anti-tumor effects of P-LPK-CPT, a peptide-camptothecin conjugate, in colorectal cancer.
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
The Immunological Contribution of a Novel Metabolism-Related Signature to the Prognosis and Anti-Tumor Immunity in Cervical Cancer.
Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney.
An Original Aspirin-Containing Carbonic Anhydrase 9 Inhibitor Overcomes Hypoxia-Induced Drug Resistance to Enhance the Efficacy of Myocardial Protection.
Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma.
A functional role of S100A4/non-muscle myosin IIA axis for pro-tumorigenic vascular functions in glioblastoma.
Matrine injection inhibits pancreatic cancer growth via modulating carbonic anhydrases- a network pharmacology-based study with in vitro validation.
Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B.
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Targeting Hypoxic Tumors with Hybrid Nanobullets for Oxygen-Independent Synergistic Photothermal and Thermodynamic Therapy.
In vivo three-dimensional evaluation of tumour hypoxia in nasopharyngeal carcinomas using FMT-CT and MSOT.
Using ESTIMATE algorithm to establish an 8-mRNA signature prognosis prediction system and identify immunocyte infiltration-related genes in Pancreatic adenocarcinoma.
Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.
Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.
Correlation between maximum standardized uptake values on FDG-PET and microenvironmental factors in patients with clinical stage IA radiologic pure-solid lung adenocarcinoma.
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
Comprehensive analysis of differentially expressed non-coding RNAs and mRNAs in gastric cancer cells under hypoxic conditions.
Differences of tumor microenvironment between stage I lepidic-positive and lepidic-negative lung adenocarcinomas.
Abundant tumor promoting stromal cells in lung adenocarcinoma with hypoxic regions.
Loss of Phd2 cooperates with BRAF(V600E) to drive melanomagenesis.
Succinate dehydrogenase B-deficient renal cell carcinoma: A case report with novel germline mutation.
CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing.
The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model.
Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth.
Necrosis degree displayed in computed tomography images correlated with hypoxia and angiogenesis in breast cancer.
Chu X, Sun J, Dai S, Liang Y, Qian X, Xu J, Zhang J
Advances in wound care 2026 Mar;15(3):168-180
Advances in wound care 2026 Mar;15(3):168-180
Nitroimidazole-Containing [(68)Ga]Ga-IPM-N001 as a New CAIX-Targeting Radionuclide Tracer.
Niu X, Cheng S, Zhang S, Zhang H, Chen K, Zhang G, Fu Y, Xu Y, Tang JJ, Huang W, Dong X, Pan P, Wan L, Wang B, Zhou R, Jiang D, Teng P
Journal of medicinal chemistry 2026 Mar 26;69(6):7474-7487
Journal of medicinal chemistry 2026 Mar 26;69(6):7474-7487
PDGFRα governs multiple cellular signals and plays a protective role in tumor progression.
Hayashi M, Okuno N, Trang LTT, Inami A, Kato Y, Hamashima T, Tung DS, Watanabe Y, Kojima R, Fujikawa M, Ejiri A, Kunisawa T, Itoh F, Muramatsu M, Dung TN, Chung DT, Van Thinh P, Minamitani T, Yanagibashi T, Fujimori T, Mori H, Makino T, Takata K, Shimizu T, Sasahara M, Yamamoto S
Neoplasia (New York, N.Y.) 2026 Jan;71:101248
Neoplasia (New York, N.Y.) 2026 Jan;71:101248
CA9+ cancer-associated fibroblasts cooperate with SPP1+ tumor-associated macrophages driving immune resistance in triple-negative breast cancer.
Ma Q, Wang J, Jiang Q
Cellular and molecular life sciences : CMLS 2026 Jan 9;83(1):54
Cellular and molecular life sciences : CMLS 2026 Jan 9;83(1):54
Mechanisms underlying the therapeutic effects of Amygdalin in treating Cervical Cancer based on multi-omics analysis.
Jiang Q, Xu R, Cheng J, Shi Y, Zhu T, Yu M, Cui X, Lin C
Journal of pharmaceutical and biomedical analysis 2026 Jan 15;268:117232
Journal of pharmaceutical and biomedical analysis 2026 Jan 15;268:117232
Understanding Glioblastoma Dynamics Using 3D Organoids and Engineered Extracellular Matrix.
McManis A, Jimenez CA, Shirolkar A, Raza Ur Rehman S, Mallick S, Murphy M, Gaharwar AK, Singh I
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22926
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22926
Identification and validation of icaritin-associated prognostic genes in hepatocellular carcinoma through network pharmacology, bioinformatics analysis, and cellular experiments.
Shi Y, Bai Y, Wu J, Yu Y, Yang X, Yang H, Jian W, Qing J
Frontiers in immunology 2025;16:1693028
Frontiers in immunology 2025;16:1693028
Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcinoma.
Zhao Y, Yang J, Jiang Y, Wu J
Frontiers in cell and developmental biology 2025;13:1629683
Frontiers in cell and developmental biology 2025;13:1629683
Understanding proneural-mesenchymal transition using patient-derived glioma stem-like cell (GSC) organoids and engineered extracellular matrix.
McManis A, Jimenez CA, Shirolkar A, Rehman SRU, Mallick S, Murphy M, Gaharwar AK, Singh I
bioRxiv : the preprint server for biology 2025 Sep 20;
bioRxiv : the preprint server for biology 2025 Sep 20;
Targeting PLOD2 induces epithelioid differentiation and improves therapeutic response in sarcomatoid renal cell carcinoma.
Chen X, Xu D, Ji Y, Dong X, Dong X, Li Z, Tan J, Sun Q, Xin H, Liu Z, Deng Q, Wen T, Jia Y, Zhu X, Liu J
Journal of advanced research 2025 Oct 16;
Journal of advanced research 2025 Oct 16;
Comprehensive pan-cancer analysis reveals CD70 as a promising therapeutic target and biomarker in clear cell renal cell carcinoma.
Zhang X, Hong B, Yu W, Miao Q, Wang W, Wang Y, Sun Z, Bo Y, Zhang J, Zhang H, Zhang N
International journal of biological macromolecules 2025 May;307(Pt 3):142079
International journal of biological macromolecules 2025 May;307(Pt 3):142079
The Diagnostic Value of Plasma Small Extracellular Vesicle-Derived CAIX Protein in Prostate Cancer and Clinically Significant Prostate Cancer: A Study on Predictive Models.
Chen H, Pang B, Liu Z, Li B, Wang Q, Fan B, Han M, Gong J, Zhou C, Chen Y, Li Y, Jiang J
The Prostate 2025 Jun;85(8):723-741
The Prostate 2025 Jun;85(8):723-741
Hypoxia upregulates the expression of PD-L1 via NPM1 in breast cancer.
Yu Y, Sun R, Hu F, Ding Z, Li X, Han J, Liang L, Wang T, Xi G, Dong X, Li Y, Zhao X, Zhang D
Journal for immunotherapy of cancer 2025 Jun 23;13(6)
Journal for immunotherapy of cancer 2025 Jun 23;13(6)
(124)I-labelled BMSC-Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP-Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis.
Pan Y, Yang X, Zeng Z, Liu F, Luo J, Shen M, Zhou W, Li J, Jiang G, Sun L, Huang H, Pan R
Journal of extracellular vesicles 2025 Jul;14(7):e70130
Journal of extracellular vesicles 2025 Jul;14(7):e70130
Co-immunization with IFI35 enhances the therapeutic effect of an adenovirus vaccine against renal carcinoma.
Lu B, Chai L, Zhang Z, Zhao G, Shao Y, Zheng Y, Jin X, Zheng J, Chai D, Ding J
International journal of biological macromolecules 2025 Jan;286:138515
International journal of biological macromolecules 2025 Jan;286:138515
Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4(QTY)-Fc as a molecular trap.
Sun C, Hao S, Wang L, Meng R, Wang H, Li W, Deng J, Yin Q, Chen X, Xiang T, Liu Z, Zheng H, Luo Z, Cai K, Wang B, Zhang S, Qing R
Cell chemical biology 2025 Aug 21;32(8):1058-1074.e6
Cell chemical biology 2025 Aug 21;32(8):1058-1074.e6
Epigenetic Regulation of Carbonic Anhydrase 9 Expression by Nitric Oxide in Human Small Airway Epithelial Cells.
Moriya Y, Kubota S, Iijima Y, Takasugi N, Uehara T
Biological & pharmaceutical bulletin 2024;47(6):1119-1122
Biological & pharmaceutical bulletin 2024;47(6):1119-1122
Using Multi-Omics Analysis to Explore Diagnostic Tool and Optimize Drug Therapy Selection for Patients with Glioma Based on Cross-Talk Gene Signature.
Yang Y, Hu C, Lei S, Bao X, Zeng Z, Cao W
Oncology research 2024;32(12):1921-1934
Oncology research 2024;32(12):1921-1934
Enhanced glycolysis causes extracellular acidification and activates acid-sensing ion channel 1a in hypoxic pulmonary hypertension.
Tuineau MN, Herbert LM, Garcia SM, Resta TC, Jernigan NL
American journal of physiology. Lung cellular and molecular physiology 2024 Oct 1;327(4):L439-L451
American journal of physiology. Lung cellular and molecular physiology 2024 Oct 1;327(4):L439-L451
A carbonic anhydrase-targeted NIR-II fluorescent cisplatin theranostic nanoparticle for combined therapy of pancreatic tumors.
Yang Y, Liu Y, Weng J, Wen X, Liu Y, Ye D
Biomaterials 2024 Mar;305:122454
Biomaterials 2024 Mar;305:122454
Comprehensive investigation of malignant epithelial cell-related genes in clear cell renal cell carcinoma: development of a prognostic signature and exploration of tumor microenvironment interactions.
Liu S, Li G, Yin X, Zhou Y, Luo D, Yang Z, Zhang J, Wang J
Journal of translational medicine 2024 Jul 1;22(1):607
Journal of translational medicine 2024 Jul 1;22(1):607
GSH/pH Dual Activatable Cross-linked and Fluorinated PEI for Cancer Gene Therapy Through Endogenous Iron De-Hijacking and in Situ ROS Amplification.
Yang S, Wu Y, Zhong W, Chen R, Wang M, Chen M
Advanced materials (Deerfield Beach, Fla.) 2024 Jan;36(2):e2304098
Advanced materials (Deerfield Beach, Fla.) 2024 Jan;36(2):e2304098
Glucagon Enhances Chemotherapy Efficacy By Inhibition of Tumor Vessels in Colorectal Cancer.
Xu Y, Ni F, Sun D, Peng Y, Zhao Y, Wu X, Li S, Qi X, He X, Li M, Zhou Y, Zhang C, Yan M, Yao C, Zhu S, Yang Y, An B, Yang C, Zhang G, Jiang W, Mi J, Chen X, Wei P, Tian G, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2307271
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2307271
Phytosesquiterpene lactones deregulate mitochondrial activity and phenotypes associated with triple-negative breast cancer metastasis.
Cheng YT, Chang DM, Tung YC, Hsiao PW, Nakagawa-Goto K, Shyur LF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156226
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156226
Schisandrin C inhibits AKT1-regulated cell proliferation in A549 cells.
Wang Z, Xie S, Li L, Liu Z, Zhou W
International immunopharmacology 2024 Dec 5;142(Pt A):113110
International immunopharmacology 2024 Dec 5;142(Pt A):113110
Pathway-based stratification of gliomas uncovers four subtypes with different TME characteristics and prognosis.
Huang R, Han B, Zhang Y, Yang J, Wang K, Liu X, Wang Z
Journal of cellular and molecular medicine 2024 Apr;28(8):e18208
Journal of cellular and molecular medicine 2024 Apr;28(8):e18208
Carbonic Anhydrase IX Controls Vulnerability to Ferroptosis in Gefitinib-Resistant Lung Cancer.
Zhang C, Lu X, Liu X, Xu J, Li J, Qu T, Dai J, Guo R
Oxidative medicine and cellular longevity 2023;2023:1367938
Oxidative medicine and cellular longevity 2023;2023:1367938
Arenobufagin increases the sensitivity of gastric cancer to cisplatin via alkaliptosis.
Liu C, Li D, Wang J, Wang Z
Heliyon 2023 Nov;9(11):e21110
Heliyon 2023 Nov;9(11):e21110
Para-toluenesulfonamide, a novel potent carbonic anhydrase inhibitor, improves hypoxia-induced metastatic breast cancer cell viability and prevents resistance to αPD-1 therapy in triple-negative breast cancer.
Chen HY, Lin CE, Wu SC, Yang ZY, Chiang YF, Huang KC, Wang KL, Ali M, Shieh TM, Chang HY, Huang TC, Hsia SM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115533
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115533
KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma.
Shen M, Pan R, Lei S, Zhang L, Zhou C, Zeng Z, Nie Y, Tian X
Cell communication and signaling : CCS 2023 Mar 2;21(1):46
Cell communication and signaling : CCS 2023 Mar 2;21(1):46
Effect of isorhamnetin on carbonic anhydrase IX expression and tumorigenesis of bladder cancer by activating PPARγ/PTEN/AKT pathway.
Zhang P, Sun Y, Shi L, Sun D, Wang L, Feng D, Ding C
Tissue & cell 2023 Jun;82:102048
Tissue & cell 2023 Jun;82:102048
Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis.
Yang X, Ou Y, Yang Y, Wang L, Zhang Y, Zhao F, Shui P, Qing J
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1242-1253
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1242-1253
Targeting Tumor Hypoxia Inhibits Aggressive Phenotype of Dedifferentiated Thyroid Cancer.
Ma B, Wen S, Luo Y, Zhang T, Yang Y, Shen C, Zhang Y, Ji Q, Qu N, Wang Y
The Journal of clinical endocrinology and metabolism 2023 Jan 17;108(2):368-384
The Journal of clinical endocrinology and metabolism 2023 Jan 17;108(2):368-384
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Shi B, Xu FF, Xiang CP, Li CY, Fan P, Wang H
Frontiers in pharmacology 2022;13:851401
Frontiers in pharmacology 2022;13:851401
Anti-tumor effects of P-LPK-CPT, a peptide-camptothecin conjugate, in colorectal cancer.
Hou L, Hou Y, Liang Y, Chen B, Zhang X, Wang Y, Zhou K, Zhong T, Long B, Pang W, Wang L, Han X, Li L, Xu C, Gross I, Gaiddon C, Fu W, Yao H, Meng X
Communications biology 2022 Nov 14;5(1):1248
Communications biology 2022 Nov 14;5(1):1248
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
Zeng Z, Lei S, Wang J, Yang Y, Lan J, Tian Q, Chen T, Hao X
Bioengineered 2022 May;13(5):12193-12210
Bioengineered 2022 May;13(5):12193-12210
The Immunological Contribution of a Novel Metabolism-Related Signature to the Prognosis and Anti-Tumor Immunity in Cervical Cancer.
Yu S, Li X, Ma M, Yang R, Zhang J, Wu S
Cancers 2022 May 13;14(10)
Cancers 2022 May 13;14(10)
Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney.
Kapur P, Gao M, Zhong H, Chintalapati S, Mitui M, Barnes SD, Zhou Q, Miyata J, Carrillo D, Malladi VS, Rakheja D, Pedrosa I, Xu L, Kinch L, Brugarolas J
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2022 Mar;35(3):333-343
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2022 Mar;35(3):333-343
An Original Aspirin-Containing Carbonic Anhydrase 9 Inhibitor Overcomes Hypoxia-Induced Drug Resistance to Enhance the Efficacy of Myocardial Protection.
Zhou W, Zhang B, Fan K, Yin X, Liu J, Gou S
Cardiovascular drugs and therapy 2022 Aug;36(4):605-618
Cardiovascular drugs and therapy 2022 Aug;36(4):605-618
Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma.
Sun Q, Wang Y, Ji H, Sun X, Xie S, Chen L, Li S, Zeng W, Chen R, Tang Q, Zuo J, Hou L, Hosaka K, Lu Y, Liu Y, Ye Y, Yang Y
Cell death & disease 2022 Aug 19;13(8):724
Cell death & disease 2022 Aug 19;13(8):724
A functional role of S100A4/non-muscle myosin IIA axis for pro-tumorigenic vascular functions in glioblastoma.
Inukai M, Yokoi A, Ishizuka Y, Hashimura M, Matsumoto T, Oguri Y, Nakagawa M, Ishibashi Y, Ito T, Kumabe T, Saegusa M
Cell communication and signaling : CCS 2022 Apr 7;20(1):46
Cell communication and signaling : CCS 2022 Apr 7;20(1):46
Matrine injection inhibits pancreatic cancer growth via modulating carbonic anhydrases- a network pharmacology-based study with in vitro validation.
Xu PL, Cheng CS, Jiao JY, Chen H, Chen Z, Li P
Journal of ethnopharmacology 2022 Apr 6;287:114691
Journal of ethnopharmacology 2022 Apr 6;287:114691
Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B.
Zhou B, Zhu Y, Xu W, Zhou Q, Tan L, Zhu L, Chen H, Feng L, Hou T, Wang X, Chen D, Jin H
Frontiers in cell and developmental biology 2021;9:741736
Frontiers in cell and developmental biology 2021;9:741736
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
Zou W, Qian C, Zhang S, Wan X, Wei Z, Li X, Wu Y, Chen W, Wang A, Zhao Y, Lu Y
Oxidative medicine and cellular longevity 2021;2021:7037786
Oxidative medicine and cellular longevity 2021;2021:7037786
Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
Meng L, Goto M, Tanaka H, Kamikokura Y, Fujii Y, Okada Y, Furukawa H, Nishikawa Y
The American journal of pathology 2021 Sep;191(9):1580-1591
The American journal of pathology 2021 Sep;191(9):1580-1591
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Zhang J, Ma X, Fan D
Foods (Basel, Switzerland) 2021 May 26;10(6)
Foods (Basel, Switzerland) 2021 May 26;10(6)
Targeting Hypoxic Tumors with Hybrid Nanobullets for Oxygen-Independent Synergistic Photothermal and Thermodynamic Therapy.
Gao D, Chen T, Chen S, Ren X, Han Y, Li Y, Wang Y, Guo X, Wang H, Chen X, Guo M, Zhang YS, Hong G, Zhang X, Tian Z, Yang Z
Nano-micro letters 2021 Mar 31;13(1):99
Nano-micro letters 2021 Mar 31;13(1):99
In vivo three-dimensional evaluation of tumour hypoxia in nasopharyngeal carcinomas using FMT-CT and MSOT.
Huang W, Wang K, An Y, Meng H, Gao Y, Xiong Z, Yan H, Wang Q, Cai X, Yang X, Zhang B, Chen Q, Yang X, Tian J, Zhang S
European journal of nuclear medicine and molecular imaging 2020 May;47(5):1027-1038
European journal of nuclear medicine and molecular imaging 2020 May;47(5):1027-1038
Using ESTIMATE algorithm to establish an 8-mRNA signature prognosis prediction system and identify immunocyte infiltration-related genes in Pancreatic adenocarcinoma.
Meng Z, Ren D, Zhang K, Zhao J, Jin X, Wu H
Aging 2020 Mar 17;12(6):5048-5070
Aging 2020 Mar 17;12(6):5048-5070
Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.
Matsumoto T, Chino H, Akiya M, Hashimura M, Yokoi A, Tochimoto M, Nakagawa M, Jiang Z, Saegusa M
Molecular carcinogenesis 2020 Dec;59(12):1409-1419
Molecular carcinogenesis 2020 Dec;59(12):1409-1419
Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.
Gu Z, Zhang H, Guo X, Cao Y
The Journal of investigative dermatology 2020 Aug;140(8):1513-1523.e5
The Journal of investigative dermatology 2020 Aug;140(8):1513-1523.e5
Correlation between maximum standardized uptake values on FDG-PET and microenvironmental factors in patients with clinical stage IA radiologic pure-solid lung adenocarcinoma.
Ichikawa T, Aokage K, Miyoshi T, Tane K, Suzuki K, Makinoshima H, Tsuboi M, Ishii G
Lung cancer (Amsterdam, Netherlands) 2019 Oct;136:57-64
Lung cancer (Amsterdam, Netherlands) 2019 Oct;136:57-64
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
Li JM, Jiang GM, Zhao L, Yang F, Yuan WQ, Wang H, Luo YQ
Oncology reports 2019 Nov;42(5):1725-1734
Oncology reports 2019 Nov;42(5):1725-1734
Comprehensive analysis of differentially expressed non-coding RNAs and mRNAs in gastric cancer cells under hypoxic conditions.
Li J, Wang X, Lu W, Xiao Y, Yu Y, Wang X, Xu C, Shen B
American journal of translational research 2018;10(3):1022-1035
American journal of translational research 2018;10(3):1022-1035
Differences of tumor microenvironment between stage I lepidic-positive and lepidic-negative lung adenocarcinomas.
Katsumata S, Aokage K, Miyoshi T, Tane K, Nakamura H, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Hayashi R, Tsuboi M, Ishii G
The Journal of thoracic and cardiovascular surgery 2018 Oct;156(4):1679-1688.e2
The Journal of thoracic and cardiovascular surgery 2018 Oct;156(4):1679-1688.e2
Abundant tumor promoting stromal cells in lung adenocarcinoma with hypoxic regions.
Nakamura H, Ichikawa T, Nakasone S, Miyoshi T, Sugano M, Kojima M, Fujii S, Ochiai A, Kuwata T, Aokage K, Suzuki K, Tsuboi M, Ishii G
Lung cancer (Amsterdam, Netherlands) 2018 Jan;115:56-63
Lung cancer (Amsterdam, Netherlands) 2018 Jan;115:56-63
Loss of Phd2 cooperates with BRAF(V600E) to drive melanomagenesis.
Liu S, Zhang G, Guo J, Chen X, Lei J, Ze K, Dong L, Dai X, Gao Y, Song D, Ecker BL, Yang R, Feltcher C, Peng K, Feng C, Chen H, Lee RX, Kerestes H, Niu J, Kumar S, Xu W, Zhang J, Wei Z, Martin JS, Liu X, Mills G, Lu Y, Guo W, Sun L, Zhang L, Weeraratna A, Herlyn M, Wei W, Lee FS, Xu X
Nature communications 2018 Dec 21;9(1):5426
Nature communications 2018 Dec 21;9(1):5426
Succinate dehydrogenase B-deficient renal cell carcinoma: A case report with novel germline mutation.
Iwashita H, Okudela K, Matsumura M, Yamanaka S, Sawazumi T, Enaka M, Udaka N, Miyake A, Hibiya T, Miyake N, Matsumoto N, Makiyama K, Yao M, Nagashima Y, Ohashi K
Pathology international 2017 Nov;67(11):585-589
Pathology international 2017 Nov;67(11):585-589
CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing.
Clark AJ, Wiley DT, Zuckerman JE, Webster P, Chao J, Lin J, Yen Y, Davis ME
Proceedings of the National Academy of Sciences of the United States of America 2016 Apr 5;113(14):3850-4
Proceedings of the National Academy of Sciences of the United States of America 2016 Apr 5;113(14):3850-4
The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model.
Woolf EC, Curley KL, Liu Q, Turner GH, Charlton JA, Preul MC, Scheck AC
PloS one 2015;10(6):e0130357
PloS one 2015;10(6):e0130357
Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth.
Chesney J, Clark J, Klarer AC, Imbert-Fernandez Y, Lane AN, Telang S
Oncotarget 2014 Aug 30;5(16):6670-86
Oncotarget 2014 Aug 30;5(16):6670-86
Necrosis degree displayed in computed tomography images correlated with hypoxia and angiogenesis in breast cancer.
Shan X, Wang D, Chen J, Xiao X, Jiang Y, Wang Y, Fan Y
Journal of computer assisted tomography 2013 Jan-Feb;37(1):22-8
Journal of computer assisted tomography 2013 Jan-Feb;37(1):22-8
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 11071-1-AP(CA9 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 11071-1-AP(CA9 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 11071-1-AP(CA9 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The CA9 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CA9. This antibody recognizes human, mouse, rat antigen. The CA9 antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC analysis.