ABIN390039

antibody from antibodies-online

Targeting: CA9 CAIX, MN

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN390039

Provider

antibodies-online

Product name

anti-Carbonic Anhydrase IX (CA9) (AA 239-263), (Center) antibody

Antibody type

Polyclonal

Antigen

This CA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-263 AA from the Central region of human CA9.

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

AA 239-263,Center

Antibody clone number

RB8629

Vial size

400 μL

Concentration

0.35 mg/mL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.

Kaluzová M, Kaluz S, Lerman MI, Stanbridge EJ
Molecular and cellular biology 2004 Jul;24(13):5757-66

---

Strict regulation of CAIX(G250/MN) by HIF-1alpha in clear cell renal cell carcinoma.

Grabmaier K, A de Weijert MC, Verhaegh GW, Schalken JA, Oosterwijk E
Oncogene 2004 Jul 22;23(33):5624-31

---

Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas.

Hedley D, Pintilie M, Woo J, Morrison A, Birle D, Fyles A, Milosevic M, Hill R
Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Nov 15;9(15):5666-74