ABIN390040

antibody from antibodies-online

Targeting: CA9 CAIX, MN

Western blot (Data presented on provider website)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN390040

Provider

antibodies-online

Product name

anti-Carbonic Anhydrase IX (CA9) (N-Term), (AA 48-78) antibody

Antibody type

Polyclonal

Antigen

This CA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-78 AA from the N-terminal region of human CA9.

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

N-Term,AA 48-78

Antibody clone number

RB18382

Vial size

400 μL

Concentration

2 mg/mL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.

Kaluzová M, Kaluz S, Lerman MI, Stanbridge EJ
Molecular and cellular biology 2004 Jul;24(13):5757-66

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Strict regulation of CAIX(G250/MN) by HIF-1alpha in clear cell renal cell carcinoma.

Grabmaier K, A de Weijert MC, Verhaegh GW, Schalken JA, Oosterwijk E
Oncogene 2004 Jul 22;23(33):5624-31

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Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas.

Hedley D, Pintilie M, Woo J, Morrison A, Birle D, Fyles A, Milosevic M, Hill R
Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Nov 15;9(15):5666-74