23903-1-AP

antibody from Proteintech Group

Targeting: CCN2 CTGF, IGFBP8

Provider product page for 23903-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [18]
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Product number: 23903-1-AP - Provider product page
Provider: Proteintech Group
Product name: CTGF antibody
Antibody type: Polyclonal
Description: CTGF antibody (Cat. #23903-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CCN2 protein structure - 23903-1-AP shown in red.

Submitted references SDC1(+) CAFs secreting CTGF drive tumour metastasis via FGFR3 signalling in cancers.

Gao GF, Ruan ZH, Zhang SB, He S, Li YQ, Lyu JL, Liu Y, Tan XL, Wang YJ, Liu ZW, Lv GZ, Chen G, Yu JH, Wei PP, Zhao JF, Sun ZT, Zhao Z, Shi Y, Liao W, Chen SW, Zhang N, Kuang DM, Guan XY, Peng RJ, Cai MY, Yao K, Bian XW, Ding PR, Luo CL, Bei JX
Gut 2026 Feb 10;

ACTN2, regulated by PRDM9, affects the growth and inflammation of vascular smooth muscle cells by interacting with PDLIM1 in intracranial aneurysms.

Zhang G, Zhao J, Yu Z, Liu H
Frontiers in molecular neuroscience 2025;18:1606973

Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.

Huang HJ, Lin YC, Ho LJ, Su RY, Liu WC, Chiu HW
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296

Adipose-derived stem cells extracellular vesicles enhance diabetic wound healing via CCN2/PI3K/AKT pathway: therapeutic potential and mechanistic insights.

Zhou YL, Ogura S, Ma H, Liang RB, Fang SY, Wang YM, Wo Y, Wang WJ, Liu DW
Stem cell research & therapy 2025 Jun 15;16(1):304

Effects and Significance of Dicliptera chinensis Polysaccharide on the Expression of Transforming Growth Factor β1/Connective Tissue Growth Factor Pathway in the Masseter and Head and Neck Skin of Rats With Radiation-Induced Fibrosis.

Fan Y, Gao L, Huang Y, Zhao L, Zhao Y, Wang X, Mo D, Lu H, Wang D
International dental journal 2025 Apr;75(2):784-796

Downregulation of the (pro)renin receptor alleviates ferroptosis-associated cardiac pathological changes via the NCOA 4-mediated ferritinophagy pathway in diabetic cardiomyopathy.

Zhang X, Dong X, Jie H, Li S, Li H, Su Y, Li L, Kang L, Dong B, Zhang Y
International immunopharmacology 2024 Sep 10;138:112605

Abundant Neutrophil-Initiated Acute Myocardial Injury Following Coxsackievirus A6 Infection.

Zhang Y, Chen S, Sun T, Duan G, Yang H, Feng H, Jiang W, Li D, Ji W, Zhu P, Jin Y
The Journal of infectious diseases 2024 May 15;229(5):1440-1450

Polystyrene microplastic-induced extracellular vesicles cause kidney-related effects in the crosstalk between tubular cells and fibroblasts.

Wang YL, Huang CC, Zheng CM, Liu WC, Lee YH, Chiu HW
Ecotoxicology and environmental safety 2024 Mar 15;273:116098

Synergistic effects of photodynamic therapy and chemotherapy: Activating the intrinsic/extrinsic apoptotic pathway of anoikis for triple-negative breast cancer treatment.

Zhang T, Wang X, Wang D, Lei M, Hu Y, Chen Z, Li Y, Luo Y, Zhang L, Zhu Y
Biomaterials advances 2024 Jun;160:213859

M(3) subtype of muscarinic acetylcholine receptor inhibits cardiac fibrosis via targeting microRNA-29b/beta-site app cleaving enzyme 1 axis.

Li W, Yu J, Yang Y, Wang J, Liu Y, Wang J, Hu J, Yuan Y, Du Z
Cardiovascular diagnosis and therapy 2024 Feb 15;14(1):143-157

N6-methyladenosine-modified circTEAD1 stabilizes Yap1 mRNA to promote chordoma tumorigenesis.

Li H, Tang Y, Ruan X, Zhang J, Liu H, Yu S, Chen H, Yang H, Zhang K, Chen K
Clinical and translational medicine 2024 Apr;14(4):e1658

hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.

Tang Y, Si Y, Liu C, Li C, Qu L, Liu Y, Fu Q, Luo Q
Stem cells international 2023;2023:8014052

Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.

Yu J, Zhao X, Yan X, Li W, Liu Y, Wang J, Wang J, Yang Y, Hao Y, Liang Z, Tao Y, Yuan Y, Du Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793

Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.

Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126

Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.

Zhao Z, Huang G, He Y, Zuo X, Han W, Li H
Tissue & cell 2023 Dec;85:102207

Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy.

Sun X, Yang Y, Sun X, Meng H, Hao W, Yin J, Ma F, Guo X, Du L, Sun L, Wu H
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9865-9876

A high-density collagen xerogel thread prevents the progression of peritoneal fibrosis.

Aoki S, Takezawa T, Nagase K, Oshikata-Mitazaki A, Morito S, Sakumoto T, Masuda M, Yamamoto-Rikitake M, Akutagawa T, Toda S
Biomaterials science 2018 Dec 18;7(1):125-138

CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer.

Yang K, Gao K, Hu G, Wen Y, Lin C, Li X
OncoTargets and therapy 2016;9:7285-7295

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