Antibody data
- Antibody Data
- Antigen structure
- References [39]
- Comments [0]
- Validations [0]
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- Product number
- 66264-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66264-1-Ig, RRID:AB_2716798
- Product name
- Cytochrome c antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Cytochrome c antibody (Cat. #66264-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2D8D11
- Vial size
- 20ul, 150ul
Submitted references Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
8a, a New Acridine Antiproliferative and Pro-Apoptotic Agent Targeting HDAC1/DNMT1.
Nrf1 Knock-Down in the Hypothalamic Paraventricular Nucleus Alleviates Hypertension Through Intervention of Superoxide Production-Removal Balance and Mitochondrial Function.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK-eIF2α-ATF4-CHOP axis.
Nitric oxide-donating and reactive oxygen species-responsive prochelators based on 8-hydroxyquinoline as anticancer agents.
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Croton tiglium essential oil compounds have anti-proliferative and pro-apoptotic effects in A549 lung cancer cell lines.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore.
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation.
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation.
RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.
A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
Total glucosides of paeony decreases apoptosis of hepatocytes and inhibits maturation of dendritic cells in autoimmune hepatitis.
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.
Mitochondrial dysfunction in high-fat diet-induced nonalcoholic fatty liver disease: The alleviating effect and its mechanism of Polygonatum kingianum.
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6.
Fibroblast growth factor 18 exerts anti-osteoarthritic effects through PI3K-AKT signaling and mitochondrial fusion and fission.
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system.
Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.
Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation.
Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential.
DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.
Hepatic stimulator substance resists hepatic ischemia/reperfusion injury by regulating Drp1 translocation and activation.
Chu BX, Li YN, Liu N, Yuan LX, Chen SY, Zhu YH, Wang JF
Frontiers in immunology 2021;12:757909
Frontiers in immunology 2021;12:757909
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Li Z, Xiao Z, Feng Y, Wang Q, Teng M
Photodiagnosis and photodynamic therapy 2021 Oct 17;:102591
Photodiagnosis and photodynamic therapy 2021 Oct 17;:102591
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
Yang K, Pei L, Zhou S, Tao L, Zhu Y
Experimental and therapeutic medicine 2021 Nov;22(5):1316
Experimental and therapeutic medicine 2021 Nov;22(5):1316
8a, a New Acridine Antiproliferative and Pro-Apoptotic Agent Targeting HDAC1/DNMT1.
Zhang Q, Wang Z, Chen X, Qiu H, Gu Y, Wang N, Wang T, Wang Z, Ma H, Zhao Y, Zhang B
International journal of molecular sciences 2021 May 24;22(11)
International journal of molecular sciences 2021 May 24;22(11)
Nrf1 Knock-Down in the Hypothalamic Paraventricular Nucleus Alleviates Hypertension Through Intervention of Superoxide Production-Removal Balance and Mitochondrial Function.
Li Y, Yu XJ, Xiao T, Chi HL, Zhu GQ, Kang YM
Cardiovascular toxicology 2021 Jun;21(6):472-489
Cardiovascular toxicology 2021 Jun;21(6):472-489
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q
Nature communications 2021 Jan 20;12(1):476
Nature communications 2021 Jan 20;12(1):476
LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK-eIF2α-ATF4-CHOP axis.
Yu XX, Zhu MY, Wang JR, Li H, Hu P, Qing YJ, Wang XY, Wang HZ, Wang ZY, Xu JY, Guo QL, Hui H
Acta pharmacologica Sinica 2021 Feb;42(2):290-300
Acta pharmacologica Sinica 2021 Feb;42(2):290-300
Nitric oxide-donating and reactive oxygen species-responsive prochelators based on 8-hydroxyquinoline as anticancer agents.
Zhang Y, Yang J, Meng T, Qin Y, Li T, Fu J, Yin J
European journal of medicinal chemistry 2021 Feb 15;212:113153
European journal of medicinal chemistry 2021 Feb 15;212:113153
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869
Food science & nutrition 2021 Apr;9(4):1860-1869
Croton tiglium essential oil compounds have anti-proliferative and pro-apoptotic effects in A549 lung cancer cell lines.
Niu QL, Sun H, Liu C, Li J, Liang CX, Zhang RR, Ge FR, Liu W
PloS one 2020;15(5):e0231437
PloS one 2020;15(5):e0231437
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway.
Feng D, Liu M, Liu Y, Zhao X, Sun H, Zheng X, Zhu J, Shang F
Oncology letters 2020 Oct;20(4):67
Oncology letters 2020 Oct;20(4):67
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore.
Zhao Y, Guo Y, Chen Y, Liu S, Wu N, Jia D
International journal of molecular medicine 2020 May;45(5):1514-1524
International journal of molecular medicine 2020 May;45(5):1514-1524
MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.
Zhang X, Wang Z, Li W, Huang R, Zheng D, Bi G
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Mar 9;30(3):523-533
SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation.
Li S, Li H, Zhang YL, Xin QL, Guan ZQ, Chen X, Zhang XA, Li XK, Xiao GF, Lozach PY, Cui J, Liu W, Zhang LK, Peng K
Cell reports 2020 Mar 31;30(13):4370-4385.e7
Cell reports 2020 Mar 31;30(13):4370-4385.e7
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
Yao X, Yu S, Jing X, Guo J, Sun K, Guo F, Ye Y
Stem cell research & therapy 2020 Mar 30;11(1):140
Stem cell research & therapy 2020 Mar 30;11(1):140
TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation.
Al-Azab M, Qaed E, Ouyang X, Elkhider A, Walana W, Li H, Li W, Tang Y, Adlat S, Wei J, Wang B, Li X
The FEBS journal 2020 Jul;287(14):3088-3104
The FEBS journal 2020 Jul;287(14):3088-3104
RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.
Reyes A, Favia P, Vidoni S, Petruzzella V, Zeviani M
PLoS genetics 2020 Jul;16(7):e1008923
PLoS genetics 2020 Jul;16(7):e1008923
A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.
Chen Y, Zhao Y, Bajor DL, Wang Z, Selfridge JE
Journal of genetics and genomics = Yi chuan xue bao 2020 Jul 20;47(7):389-395
Journal of genetics and genomics = Yi chuan xue bao 2020 Jul 20;47(7):389-395
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Hua W, Li S, Luo R, Wu X, Zhang Y, Liao Z, Song Y, Wang K, Zhao K, Yang S, Yang C
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
He J, He J, Min L, He Y, Guan H, Wang J, Peng X
International journal of cancer 2020 Feb 15;146(4):1052-1063
International journal of cancer 2020 Feb 15;146(4):1052-1063
Total glucosides of paeony decreases apoptosis of hepatocytes and inhibits maturation of dendritic cells in autoimmune hepatitis.
Shen M, Men R, Fan X, Wang T, Huang C, Wang H, Ye T, Luo X, Yang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109911
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109911
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z
Oxidative medicine and cellular longevity 2019;2019:6521218
Oxidative medicine and cellular longevity 2019;2019:6521218
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Zhao C, He R, Shen M, Zhu F, Wang M, Liu Y, Chen H, Li X, Qin R
Frontiers in pharmacology 2019;10:968
Frontiers in pharmacology 2019;10:968
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Yang N, Li C, Li H, Liu M, Cai X, Cao F, Feng Y, Li M, Wang X
Frontiers in pharmacology 2019;10:709
Frontiers in pharmacology 2019;10:709
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
Yao X, Jing X, Guo J, Sun K, Deng Y, Zhang Y, Guo F, Ye Y
Frontiers in pharmacology 2019;10:163
Frontiers in pharmacology 2019;10:163
Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.
Liu T, Li X, Wu M, Qin L, Chen H, Qian P
Frontiers in microbiology 2019;10:1202
Frontiers in microbiology 2019;10:1202
Mitochondrial dysfunction in high-fat diet-induced nonalcoholic fatty liver disease: The alleviating effect and its mechanism of Polygonatum kingianum.
Yang XX, Wang X, Shi TT, Dong JC, Li FJ, Zeng LX, Yang M, Gu W, Li JP, Yu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109083
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109083
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Shen J, Wang J, Du J, Wang L, Zhou X, Chang X, Li Z, Zhai X, Zuo D, Wu Y
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6.
Yang Y, Wu N, Wu Y, Chen H, Qiu J, Qian X, Zeng J, Chiu K, Gao Q, Zhuang J
Cell death & disease 2019 Nov 13;10(11):862
Cell death & disease 2019 Nov 13;10(11):862
Fibroblast growth factor 18 exerts anti-osteoarthritic effects through PI3K-AKT signaling and mitochondrial fusion and fission.
Yao X, Zhang J, Jing X, Ye Y, Guo J, Sun K, Guo F
Pharmacological research 2019 Jan;139:314-324
Pharmacological research 2019 Jan;139:314-324
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, Yang H, Wang Z
Cells 2019 Dec 27;9(1)
Cells 2019 Dec 27;9(1)
Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system.
Yamada S, Sakakibara SI
The Journal of comparative neurology 2018 Sep 1;526(13):2099-2114
The Journal of comparative neurology 2018 Sep 1;526(13):2099-2114
Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.
Deng F, Wang S, Zhang L, Xie X, Cai S, Li H, Xie GL, Miao HL, Yang C, Liu X, Xia Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(1):279-292
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(1):279-292
Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation.
Deng F, Wang S, Cai S, Hu Z, Xu R, Wang J, Feng D, Zhang L
Oxidative medicine and cellular longevity 2017;2017:3542149
Oxidative medicine and cellular longevity 2017;2017:3542149
Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential.
Huo X, Wang C, Yu Z, Peng Y, Wang S, Feng S, Zhang S, Tian X, Sun C, Liu K, Deng S, Ma X
Journal of pineal research 2017 May;62(4)
Journal of pineal research 2017 May;62(4)
DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.
Zhang Y, Gong FL, Lu ZN, Wang HY, Cheng YN, Liu ZP, Yu LG, Zhang HH, Guo XL
The international journal of biochemistry & cell biology 2017 Dec;93:1-11
The international journal of biochemistry & cell biology 2017 Dec;93:1-11
Hepatic stimulator substance resists hepatic ischemia/reperfusion injury by regulating Drp1 translocation and activation.
Zhang C, Huang J, An W
Hepatology (Baltimore, Md.) 2017 Dec;66(6):1989-2001
Hepatology (Baltimore, Md.) 2017 Dec;66(6):1989-2001
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