Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [1]
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Validation data
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- Product number
- V2785 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Cytochrome C Antibody
- Antibody type
- Monoclonal
- Antigen
- Rat full-length protein was used as the immunogen for the Cytochrome C antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 6H2.B4
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the Cytochrome C antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references NF-κB pathway controls mitochondrial dynamics.
mTORC1 and mTORC2 have largely distinct functions in Purkinje cells.
Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.
Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans.
CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation.
Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signaling pathways
Establishment of a specific cell death induction system in Bombyx mori by a transgene with the conserved apoptotic regulator, mouse Bcl-2-associated X protein (mouse Bax).
Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration.
BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs.
Laforge M, Rodrigues V, Silvestre R, Gautier C, Weil R, Corti O, Estaquier J
Cell death and differentiation 2016 Jan;23(1):89-98
Cell death and differentiation 2016 Jan;23(1):89-98
mTORC1 and mTORC2 have largely distinct functions in Purkinje cells.
Angliker N, Burri M, Zaichuk M, Fritschy JM, Rüegg MA
The European journal of neuroscience 2015 Oct;42(8):2595-612
The European journal of neuroscience 2015 Oct;42(8):2595-612
Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.
Catalán E, Jaime-Sánchez P, Aguiló N, Simon MM, Froelich CJ, Pardo J
The Journal of biological chemistry 2015 Mar 13;290(11):6868-77
The Journal of biological chemistry 2015 Mar 13;290(11):6868-77
Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans.
Coelho C, Souza AC, Derengowski Lda S, de Leon-Rodriguez C, Wang B, Leon-Rivera R, Bocca AL, Gonçalves T, Casadevall A
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 1;194(5):2345-57
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 1;194(5):2345-57
CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation.
Liu Y, Clegg HV, Leslie PL, Di J, Tollini LA, He Y, Kim TH, Jin A, Graves LM, Zheng J, Zhang Y
Cell death and differentiation 2015 Jun;22(6):1035-46
Cell death and differentiation 2015 Jun;22(6):1035-46
Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N
Molecular and cellular biology 2015 Jan;35(1):211-23
Molecular and cellular biology 2015 Jan;35(1):211-23
Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signaling pathways
Fallaize D, Chin L, Li L
Cellular Signalling 2015 December;27(12):2543-2554
Cellular Signalling 2015 December;27(12):2543-2554
Establishment of a specific cell death induction system in Bombyx mori by a transgene with the conserved apoptotic regulator, mouse Bcl-2-associated X protein (mouse Bax).
Sumitani M, Sakurai T, Kasashima K, Kobayashi S, Uchino K, Kanzaki R, Tamura T, Sezutsu H
Insect molecular biology 2015 Dec;24(6):671-80
Insect molecular biology 2015 Dec;24(6):671-80
Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration.
Bernard-Marissal N, Médard JJ, Azzedine H, Chrast R
Brain : a journal of neurology 2015 Apr;138(Pt 4):875-90
Brain : a journal of neurology 2015 Apr;138(Pt 4):875-90
BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs.
Fox JL, Storey A
Cancer research 2015 Apr 1;75(7):1345-55
Cancer research 2015 Apr 1;75(7):1345-55
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of HL-60 cell lysate with Cytochrome C antibody (clone 6H2.B4). Predicted molecular weight: ~12kDa, routinely visualized at ~15kDa.
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free Cytochrome C Antibody (clone 6H2.B4). Confirmation of Integrity and Purity of the Antibody.