Antibody data

Product number
Ab098695 - Provider product page
Provider
Aladdin Scientific
Product name
Cytochrome C Mouse mAb
Antibody type
Monoclonal
Description
Mouse anti Human Cytochrome C Antibody, Monoclonal (C2), could be used for WB,IHC,ICC,IF and so on. Application: WB: 0.01-2µg/mL IHC: 5-30µg/mL ICC/IF: 5-30µg/mL Protein Function Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Reactivity
Human, Mouse, Rat, Canine, Porcine
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
AA 5-100
Antibody clone number
C2
Vial size
100_l,10_l,1ml,20_l,50_l
Concentration
Lot by Lot
Storage
Store at 4_ short term (1-2 weeks). Store at -20_ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
CYCS protein structure - Ab098695 shown in red.