Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- AF603 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse Ephrin-A2 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse Ephrin-A2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) Ephrin-A1, rmEphrin-A4, and rmEphrin-A5 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
P52801
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins.
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.
p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping.
Dewannieux M, Vernochet C, Ribet D, Bartosch B, Cosset FL, Heidmann T
PLoS pathogens 2011 Oct;7(10):e1002309
PLoS pathogens 2011 Oct;7(10):e1002309
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.
Irie N, Takada Y, Watanabe Y, Matsuzaki Y, Naruse C, Asano M, Iwakura Y, Suda T, Matsuo K
The Journal of biological chemistry 2009 May 22;284(21):14637-44
The Journal of biological chemistry 2009 May 22;284(21):14637-44
p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping.
Lim YS, McLaughlin T, Sung TC, Santiago A, Lee KF, O'Leary DD
Neuron 2008 Sep 11;59(5):746-58
Neuron 2008 Sep 11;59(5):746-58
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Ephrin-A2 in Rat Hippocampal Neurons. Ephrin-A2 was detected in immersion fixed rat hippocampal neurons using 10 µg/mL Goat Anti-Mouse Ephrin-A2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF603) for 3 hours at room temperature. Neurons were stained (green) and glial cells were labeled by using anti-GFAP antibodies (red). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.