Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11600-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11600-1-AP, RRID:AB_10640577
- Product name
- HCK antibody
- Antibody type
- Polyclonal
- Description
- HCK antibody (Cat. #11600-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8(+) T cell immunity in TNBC.
Characterization of NLRP3 Inflammasome-Associated Hub Genes in the Progression of Diabetic Nephropathy.
Immune activation contributes recovery following pulmonary impairments by silica nanoparticles.
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Urinary TYROBP and HCK as genetic biomarkers for non-invasive diagnosis and therapeutic targeting in IgA nephropathy.
Macrophages-Related Genes Biomarkers in the Deterioration of Atherosclerosis.
Hematopoietic Cell Kinase (HCK) Is Essential for NLRP3 Inflammasome Activation and Lipopolysaccharide-Induced Inflammatory Response In Vivo.
Liang Y, Zeng Q, Xiao M, Li P, He R, Chen Z, Liu J, Cao J, Li J, Yin L, Zhong J, Chen X, Feng J, He J, Chen X, Zu X, Shen Y
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):985-1008
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):985-1008
Characterization of NLRP3 Inflammasome-Associated Hub Genes in the Progression of Diabetic Nephropathy.
Zhao S, Li Y, Li W, Dong L, Lian R, Luo Q, Lian X, Li J, He F
Immunity, inflammation and disease 2026 Apr;14(4):e70424
Immunity, inflammation and disease 2026 Apr;14(4):e70424
Immune activation contributes recovery following pulmonary impairments by silica nanoparticles.
Guo C, Zhao X, Li Y, Wang D, Xu H, Lv S, Li X, Li Y
Journal of hazardous materials 2025 Sep 15;496:139403
Journal of hazardous materials 2025 Sep 15;496:139403
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Gong J, Sun D, Zheng Y, Mao C, Yu B, Li X, Xuan Y
Food science & nutrition 2025 Dec;13(12):e71341
Food science & nutrition 2025 Dec;13(12):e71341
Urinary TYROBP and HCK as genetic biomarkers for non-invasive diagnosis and therapeutic targeting in IgA nephropathy.
Xie B, Pang S, Xie Y, Tan Q, Li S, Jili M, Huang Y, Zhao B, Yuan H, Mi J, Chen X, Ruan L, Chen H, Li X, Hu B, Huang J, Yang R, Li W
Frontiers in genetics 2024;15:1516513
Frontiers in genetics 2024;15:1516513
Macrophages-Related Genes Biomarkers in the Deterioration of Atherosclerosis.
Zheng Y, Qi B, Gao W, Qi Z, Liu Y, Wang Y, Feng J, Cheng X, Luo Z, Li T
Frontiers in cardiovascular medicine 2022;9:890321
Frontiers in cardiovascular medicine 2022;9:890321
Hematopoietic Cell Kinase (HCK) Is Essential for NLRP3 Inflammasome Activation and Lipopolysaccharide-Induced Inflammatory Response In Vivo.
Kong X, Liao Y, Zhou L, Zhang Y, Cheng J, Yuan Z, Wang S
Frontiers in pharmacology 2020;11:581011
Frontiers in pharmacology 2020;11:581011
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 11600-1-AP(HCK antibody) at dilution of 1:100
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The HCK antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HCK. This antibody recognizes human, mouse, rat antigen. The HCK antibody has been validated for the following applications: ELISA, WB, IHC analysis.