11098-1-AP

antibody from Proteintech Group

Targeting: FGFR4 CD334, JTK2

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

11098-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11098-1-AP, RRID:AB_2103657

Product name

FGFR4 antibody

Antibody type

Polyclonal

Description

FGFR4 antibody (Cat. #11098-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Blautia coccoides Alleviates Acute Pancreatitis via Bile Salt Hydrolase-mediated Deoxycholic Acid Production and Farnesoid X Receptor Signaling.

Fu Y, Xu B, Qin W, Xiao W, Huang H, Hu J, Cui M, Mei Q, Fan J, Huang C, Zeng Y
Cellular and molecular gastroenterology and hepatology 2026;20(5):101732

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The D826V point mutation in IREB2 induces lipogenesis in adipose tissues.

Lv Y, Wu C, Xiao J, Yang W, Wang C, Wang J, Huang J, Guo Z, Liao S
Frontiers in cell and developmental biology 2026;14:1724485

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DOT1L promotes phenotypic transition of vascular smooth muscle cells following vascular injury in diabetes through activation of the FGFR4/PI3K/AKT/Jag/Notch signaling pathway.

Zhang J, Wu D, Cheng C, Yang Z, Chen Z, Liu L, Li W, Wang W, Huang C, Yang J
Cellular signalling 2026 Feb;138:112223

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Inulin and Lycium barbarum polysaccharides mitigate the diabetic inflammatory response by modulating bile acid metabolism to enhance regulatory T cell (Treg) activation in a rat model of diabetes.

Lu H, Luo H, Li P, Yang Y, Cao S, Zhang Y, Ma H, Zhao Q, Zheng Y, Wang H
Frontiers in endocrinology 2025;16:1705635

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Fibroblast growth factor 19 regulates polycystic ovary syndrome progression via FGFR4-ERK-NRF2 pathway.

Qu J, Qiu M, Wang J, Chen Z, Chen M, Teng X, Li Y
Frontiers in cell and developmental biology 2025;13:1626938

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Single-cell profiles delineate immune cell remodeling and enhanced tumor-fibroblast interaction of hepatoblastoma after chemotherapy.

Chen D, Zhan Y, Zhou E, Chen H, Dai S, Yang R, Ye C, Wang J, Li Y, Lu Y, Fang Y, Chen L, Yao W, Li K, Zheng S, Dong K, Wang J, Dong R
Cell reports. Medicine 2025 Oct 21;6(10):102401

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Tanaka A, Otani Y, Klimstra DS, Basturk O, Vyas MM, Wang JY, Roehrl MHA
Biomarker research 2025 Nov 27;13(1):159

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Radiogenomics of intrahepatic cholangiocarcinoma predicts immunochemotherapy response and identifies therapeutic target.

Ji GW, Xu ZG, Liu SC, Cao SY, Jiao CY, Lu M, Zhang B, Yang Y, Xu Q, Wu XF, Wang K, Xia YX, Li XC, Wang XH
Clinical and molecular hepatology 2025 Jul;31(3):935-959

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Hepatic FXR-FGF4 is required for bile acid homeostasis via an FGFR4-LRH-1 signal node under cholestatic stress.

Song L, Hou Y, Xu D, Dai X, Luo J, Liu Y, Huang Z, Yang M, Chen J, Hu Y, Chen C, Tang Y, Rao Z, Ma J, Zheng M, Shi K, Cai C, Lu M, Tang R, Ma X, Xie C, Luo Y, Li X, Huang Z
Cell metabolism 2025 Jan 7;37(1):104-120.e9

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Hepatocyte-Derived FGF1 Alleviates Isoniazid and Rifampicin-Induced Liver Injury by Regulating HNF4α-Mediated Bile Acids Synthesis.

Lin Q, Zhang J, Qi J, Tong J, Chen S, Zhang S, Liu X, Lou H, Lv J, Lin R, Xie J, Jin Y, Wang Y, Ying L, Wu J, Niu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2408688

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Wnt/FGF20 signaling axis promotes migration of proximal blastema cell during tail regeneration of Gekko japonicus.

Xu M, Li Z, Yu J, Li M, Zhang Y, Huang S, Xu Y, Chen X, Wu R, Liu M, Liu Y
Communications biology 2025 Dec 15;9(1):94

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Lingguizhugan oral solution alleviates MASLD by regulating bile acids metabolism and the gut microbiota through activating FXR/TGR5 signaling pathways.

Wang J, Zang J, Yu Y, Liu Y, Cao H, Guo R, Zhang L, Liu M, Zhang Z, Li X, Kong L
Frontiers in pharmacology 2024;15:1426049

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FGF19-Based Mini Probe Targeting FGFR4 for Diagnosis and Surgical Navigation of Hepatocellular Carcinoma.

Cai J, Lian C, Lu Z, Shang Q, Wang L, Han Z, Gu Y
Journal of medicinal chemistry 2024 Mar 14;67(5):3764-3777

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Soutto M, Zhang X, Bhat N, Chen Z, Zhu S, Maacha S, Genoula M, El-Gazzaz O, Peng D, Lu H, McDonald OG, Chen XS, Cao L, Xu Z, El-Rifai W
Redox biology 2024 Feb;69:102998

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Fucogalactan Sulfate (FS) from Laminaria japonica Regulates Lipid Metabolism in Diet-Induced Humanized Dyslipidemia Mice via an Intestinal FXR-FGF19-CYP7A1/CYP8B1 Pathway.

Song J, Lu X, Liu D, Zhang Y, Zhai X, Zhou L, Gao J
Journal of agricultural and food chemistry 2023 Sep 27;71(38):14027-14037

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The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression.

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Journal of experimental & clinical cancer research : CR 2023 Oct 11;42(1):263

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Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors.

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Berbamine dihydrochloride suppresses the progression of colorectal cancer via RTKs/Akt axis.

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The UCMSC-bFGF/Scaffold System Accelerates the Healing of the Uterine Full-Thickness Injury.

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FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2(-/-) Mouse Model of Primary Sclerosing Cholangitis.

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FGFR4 Gly388Arg Polymorphism Affects the Progression of Gastric Cancer by Activating STAT3 Pathway to Induce Epithelial to Mesenchymal Transition.

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Characterization of a Spontaneously Immortalized Murine Müller Glial Cell Line QMMuC-1.

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Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HepG2 cells were subjected to SDS PAGE followed by western blot with 11098-1-AP(FGFR4 antibody) at dilution of 1:400

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The FGFR4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FGFR4. This antibody recognizes human, mouse, rat antigen. The FGFR4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Appendix

11098-1-AP.pdf

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