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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN350042 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350042, RRID:AB_10782359
- Product name
- anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (Extracellular Domain) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the extracellular domain of rat amiloride sensitive cation channel 2, neuronal (ACCN2, ASIC1) conjugated to an immunogenic carrier protein was used as the antigen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Extracellular Domain
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).
Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+.
BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels.
The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans.
Cloning and expression of a novel human brain Na+ channel.
Hruska-Hageman AM, Wemmie JA, Price MP, Welsh MJ
The Biochemical journal 2002 Feb 1;361(Pt 3):443-50
The Biochemical journal 2002 Feb 1;361(Pt 3):443-50
Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+.
Babinski K, Catarsi S, Biagini G, Séguéla P
The Journal of biological chemistry 2000 Sep 15;275(37):28519-25
The Journal of biological chemistry 2000 Sep 15;275(37):28519-25
BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels.
García-Añoveros J, Derfler B, Neville-Golden J, Hyman BT, Corey DP
Proceedings of the National Academy of Sciences of the United States of America 1997 Feb 18;94(4):1459-64
Proceedings of the National Academy of Sciences of the United States of America 1997 Feb 18;94(4):1459-64
The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans.
Waldmann R, Champigny G, Voilley N, Lauritzen I, Lazdunski M
The Journal of biological chemistry 1996 May 3;271(18):10433-6
The Journal of biological chemistry 1996 May 3;271(18):10433-6
Cloning and expression of a novel human brain Na+ channel.
Price MP, Snyder PM, Welsh MJ
The Journal of biological chemistry 1996 Apr 5;271(14):7879-82
The Journal of biological chemistry 1996 Apr 5;271(14):7879-82
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