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- Antibody Data
- Antigen structure
- References [10326]
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- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 10494-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10494-1-AP, RRID:AB_2263076
- Product name
- GAPDH antibody
- Antibody type
- Polyclonal
- Description
- GAPDH antibody (Cat. #10494-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig, arabidopsis , corn , cabbage, rice and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references A Novel Autophagy Inhibitor p-Hydroxylcinnamaldehyde Suppresses Esophageal Squamous Cell Carcinoma by Targeting LDHA Phosphorylation-Mediated Metabolic Reprogramming.
Lymph Node Metastasis-Associated Spatiotemporal Mapping of the TFF3-Linked Niche in Breast Cancer: Integrating Radiogenomic Signatures with Immune-Ecosystem Remodeling.
Glucocorticoid-dependence and independence of the circadian liver transcriptome.
POFUT2 Mediated Fucosylation of JUP Enhances VEGFA Expression to Promote Angiogenesis in Colorectal Cancer.
Tumor-Derived CXCL10 and CCL20 Polarize the Immune Microenvironment in Nasopharyngeal Carcinoma via Competitive Recruitment of Effector T Cells and Tregs.
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
Parkin Deficiency Impairs ER-Mitochondria Associations and calcium homeostasis via IP3R-Grp75-VDAC1 Complex.
Schisandrin B Targets PXR to Enhance Bile Acid Metabolism and Alleviate ANIT-Induced Cholestatic Liver Injury via Dual Pathways.
Targeting Myeloid FoxO1 Ameliorates Sepsis-induced Intestinal Injury by Modulating Tim4(+) Macrophage Glycolysis.
Integrative bioinformatics and experiments identify RIBC2 as a key regulator in the esophageal cancer.
Spatholobus suberectus Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling.
AJUBA: The Master Regulator Bridging EMT and Immune Evasion in Colorectal Cancer.
Hsa_circ_0000313/miR-1224-3p/MKNK2 Axis Modulates CD4(+) T Cells by Activating p38 MAPK Signaling in Myasthenia Gravis.
A Novel MAP3K7 Variant Causing Loss of Function Identified in a Family With Cardiospondylocarpofacial Syndrome: Functional Validation and Molecular Insights.
Multiomics Analysis Identifies Chromosomal Instability-Associated Immune-Related Signatures in Hepatocellular Carcinoma by Integrating Weighted Gene Coexpression Network Analysis (WGCNA) and Machine Learning.
PAPPA2 c.392G>C Heterozygous Mutation Associates Primary Open-Angle Glaucoma in a Chinese Family.
Adipose Mesenchymal Stem Cells Promote Wound Healing by Modulating Expression of SERPINE1 in Dermal Fibroblasts and Keratinocytes.
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
X-Box Binding Protein 1 Regulates Osteogenesis of Periodontal Ligament Cells During Aging by Modulating P53 Signaling Pathway.
Gut-Derived Hippuric Acid Alleviates Hepatic Lipid Metabolism via UGDH/FOXK1/CD36 Axis in Obese Mice.
Enhancing oligodendrocytes generation and myelin renewal by vitamin C mitigate Parkinson-relevant phenotypes in a murine model of Parkinson's disease.
A Five-Gene PANoptosis Signature Correlates with Immune Infiltration and Secondary Brain Injury in Intracerebral Hemorrhage.
Protective Effects of Cyclosporin H Against Sepsis-Induced Acute Kidney Injury via Modulation of Fpr1 Signaling and Inhibiting Pyroptosis.
Anjiang formula inhibits PVN microglial activation and lowers blood pressure by targeting RhoA/ROCK2 pathway: a retrospective clinical and experimental study.
Oncolytic adenovirus encoding a TGF-β inhibitor synergizes with PD-1 blockade to potentiate NK cell cytotoxicity against NSCLC.
3-Hydroxystearic acid promotes cholesterol efflux and attenuates atherosclerosis via the ALKBH5/PAX-8/ABCA1 pathway.
Loss of the translational repressor 4E-BP1 promotes skin carcinogenesis.
Apigenin ameliorates postoperative inflammation and accelerates wound healing in a rat model of perianal abscess by targeting the JAK1/STAT3 pathway in macrophages.
PLA-THF-PEG nanoparticles Co-encapsulating AV3 and KH3 for synergistic pancreatic cancer therapy via stromal remodeling and metabolic inhibition.
Wuji Wan ameliorates ulcerative colitis by restoring impaired membrane transport.
METTL14 modulates the nasopharyngeal carcinoma microenvironment via m(6)A-modified YWHAH identified through single-cell and machine learning analyses.
Crocin protects against smoke-induced chronic obstructive pulmonary disease by regulating AKT1.
Unveiling potential diagnostic biomarkers for rheumatoid arthritis through integrated gene expression analysis.
Luteolin mitigates proliferative vitreoretinopathy through inhibition of ERK1/2 signaling and epithelial-mesenchymal transition.
Identification of m1A/m6A/m5C/m7G-related genes and clusters associated with neuropathic pain.
Splicing factor FUS facilitates the progression of PIT1-lineage PitNETs by upregulating MDM2.
CD146(+) pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.
TM9SF4 acts as a receptor mediating Glaesserella parasuis cytolethal distending toxin-induced cytotoxicity in PK15 cells.
Effects of low-serum adaptation on growth and protein expression in stably lactoferrin-overexpressing mammary alveolar cells.
Functionalized magnetic hydrogel encapsulation of human dental follicle stem cells under a static magnetic field enhances multi-site bone regeneration.
Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization.
The brain imaging feature-related gene NRP2 drives the malignant progression of glioblastoma through the FAK pathway: a Mendelian randomization study.
Heart-nosed bat alphacoronaviruses use human CEACAM6 to enter cells.
PRSS23 functions downstream of ZEB1 to promote esophageal squamous cell carcinoma progression by driving M2 polarization of tumor associated macrophages.
The coordinated action of UFMylation and the RQC pathways clears arrested polypeptides at the ER.
BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia.
Farnesol Targets the GSTP1/MAPK Axis to Inhibit Trauma-Induced Tendon Heterotopic Ossification.
Periplogenin Suppresses Hepatocarcinogenesis by Inducing Cellular Senescence via the Activating FOXO1/P53 Signaling Pathway.
Asiatic Acid Ameliorates MNNG-Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis.
Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis.
Downregulation of integrin α3 in ADHD mirrored in mutant mouse model by dopamine-dependent hippocampal AMPAR expression.
Lipid-trap mass spectrometry identifies lipid-protein interactions in cells.
NRH attenuates age-related hearing loss by suppressing cochlear ferroptosis and cellular senescence via Sirt3 activation.
ALDH5A1 as a key in osteonecrosis of the femoral head: Insights from bioinformatics and experimental validation.
Detoxification of T-2 toxin in human chondrocytes due to its hydroxylation by carboxylesterases and arylacetamide deacetylase in the liver.
High-fat diet perturbs hepatic lipid metabolism and impairs colonic autophagy to exacerbate experimental colitis.
High-throughput screened kaempferitrin potentiates trastuzumab efficacy in HER2-positive gastric cancer by targeting Cyclooxygenase-2 to inhibit ERK signaling.
Bufei Jianspi formula alleviates intestinal epithelial barrier injury by inhibition of calpain 2 in COPD rat.
Macrophage Membrane-Cloaked, ROS-Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome.
BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer-Associated Fibroblasts Crosstalk.
Promotion of DFU Wound Healing via BRG1-COL16A1 Axis in Fibroblasts.
Cuproptosis and Disulfidptosis Converge to Empower PD-L1 Checkpoint Therapy via Cadict-Induced PD-L1 Translation.
Ultrasound-assisted extraction optimization of Fructus Tribuli polysaccharides: How stir-frying processing alters structures and enhances antihypertensive efficacy.
Fluorescence polarization-based discovery of natural RORγ orthosteric inhibitors.
Discovery of potent TNIK inhibitors containing a 1H-pyrrolo[2,3-b]pyridine scaffold as promising therapeutics for colorectal cancer.
tRF-1432 orchestrates RBMS1-IMPDH2 regulatory control to drive purine-dependent chemoresistance in breast cancer.
Chaihu-Shugan San ameliorates perimenopausal obesity with depression by coordinately targeting hepatic PGC-1α/CYP8B1/PPARγ signaling and gut barrier integrity.
Saikosaponin D alleviates chronic prostatitis/chronic pelvic pain syndrome by regulating the NF-κB pathway via lncRNA5682.
Tacrolimus-accelerated renal interstitial injury in subtotal nephrectomized rats and its pharmacological modulation by everolimus.
Multi-omics analysis and preliminary experimental validation of acetyl tributyl citrate (ATBC) promoting bladder cancer progression via the AKR1B1/EMT axis.
F-53B exposure accelerates progression from preexisting fatty liver to non-alcoholic steatohepatitis and hepatic fibrosis.
Glutaredoxin-1 attenuates transactive response DNA-binding protein 43-induced neurotoxicity by suppressing oxidative stress and transactive response DNA-binding protein 43 aggregation.
Inflammation-responsive framework nucleic acids for ulcerative colitis therapy.
Dual-action nasal spray with mussel protein and xylitol restores epithelial barrier and attenuates type 2 inflammation in allergic rhinitis.
Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver.
The modified Zuojin formula (SQQT) associates ILC2-linked JAK-2/STAT5/c-Myc cascade and gastric metaplasia regression.
Naringenin inhibits Ferroptosis and ameliorates interstitial cystitis with metabolic syndrome by activating the Nrf2/NQO-1 pathway.
Grape Seed Proanthocyanins Extract Ameliorates the Neurotoxicity Induced by Fluoride Through mTOR/p70s6k Signaling Pathway in Vivo and in Vitro.
Cytoskeletal-related genes function as checkpoints for the maintenance of VSMC contractile phenotype and prevent pathological remodeling in arterial diseases.
Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers.
Cadmium targeting MLKL-Drp1 axis to trigger mitochondrial oxidative stress contributes to necroinflammation in rat kidney.
Oncogenic role of talin-1 in glioma: Association with poor prognosis and regulation of the TGF-beta signaling pathway.
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.
Concurrent Ferroptosis and Apoptosis in Resveratrol-Treated Glioblastoma Cells: Relevance With NRF2 Downregulation and Oxidative Stress.
Rg1-R1 attenuates cardiac ischemia/reperfusion-induced endothelial cell injury through activating the ULK1/PGAM5-FUNDC1-mitophagy pathway.
The miR-2110/TRAF3 axis is associated with endothelial dysfunction and atherosclerosis in coronary heart disease.
Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short-Chain Fatty Acids.
Modification of 3D printed porous titanium implants with on-demand delivery of curcumin and stromal cell derived factor-1 for osseointegration improvement.
α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis.
NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma.
Alpha-Fetoprotein Stimulates Cleavage of Membranal MICA/B on Liver Cancer Cell Lead to Escape Immune Surveillance of Natural Killer Cells.
Acceleration of Lactate Uptake and Utilization Contributes to Neuroprotective Action of FGF21 Involved in Naturally Aging Mice.
The Relationship Between Gut Microbiota-Related Hippocampal Tryptophan Metabolite and Alzheimer's Disease-Like Neurobehavioral Changes Induced by Chronic Inorganic Arsenic Exposure in Rats.
OPTN knockout alleviates OVA-induced airway inflammation in a mouse model of asthma.
Novel Ce/Cu-modified black ceramics disrupted mitochondrial dysfunction and tricarboxylic acid cycle to induce cuproptosis in osteosarcoma cells.
Characterization and therapy of fertilization failure in murine and human models with HNRNPR mutations.
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
A novel proteolysis-targeting chimera strategy targeting multiple immune checkpoints containing ITIMs enhances antitumor immunity.
IL-11 Drives Dermal Fibroblast Activation in Mechanical Stretch-Mediated Skin Expansion.
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
Targeting CDK12 rescues C/EBPβ-mediated platinum and PARP inhibitor resistance in ovarian cancer.
tRF-Ser-TGA-011 impedes gastric cancer progression by targeting the MAP3K13/JNK signaling cascade.
YTHDF3-TRIM2-P53 axis promotes malignant progression in uveal melanoma (UVM).
ED-71 prevents glucocorticoid-induced bone loss by inhibiting type H vascular endothelial cell senescence through maintaining mitochondria-associated membrane-mediated calcium homeostasis.
Nuclear and cytoplasmic USP30-AS1 coordinately regulate breast cancer progression through HnRNPF/p21 and EZH2/c-Myc/p21 axes.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Targeting IL27RA Enhances Immunotherapy in Triple-Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment.
CYP-mediated metabolic divergence underpins oxoglaucine selectivity: Detoxification in healthy hepatocytes versus mitochondrial apoptosis in hepatocellular carcinoma.
Extracellular tau oligomers exert neurocytotoxicity by triggering mitochondrial dysfunction.
Dietary urolithin a improves hepatic antioxidant function and laying performance in aging hens via Nrf2 signaling pathway activation.
Silencing progestagen-associated endometrial protein (PAEP) suppresses sorafenib resistance and enhances sorafenib-induced ferroptosis in hepatocellular carcinoma.
Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis.
Regulation of mitophagy by Fis1 and Fascin1-organized actin.
Structural basis of EGF-repeat O-glucosylation by the protein O-glucosyltransferase POGLUT2.
An integrated network pharmacology and proteomics approach reveals the anti-fibrotic effect of Fushen Granule on peritoneal fibrosis.
Nature-inspired confined cascade enzyme nanoreactors for targeted atherosclerosis therapy.
Improve the efficiency of gene silencing through 2'-O-methyl modification of the bases in siRNA terminus.
Microglia Dld-K127 lactylation promotes Parkinson's disease via regulating the metabolism of lactate-pyruvate transformation.
Rejuvenation of THY1(+) nucleus pulposus-derived stem cells promotes intervertebral disc regeneration through FGF10-FGFR1-CREB pathway and mitochondrial fission.
Association of lncRNA AGAP11 with prognosis and malignant progression in triple-negative breast cancer.
Exercise attenuates high-fat diet-induced liver injury in mice via PPARα pathway and reduction of oxidative stress and inflammation.
Boron Triggers Hepatic Ferroptosis: Unveiling the Dual-Pathogenic Nexus of Oxidative Stress and SLC7A11/GPX4 Dysregulation.
Kukoamine B Inhibits EMT in Lung Adenocarcinoma Cells by Regulating Intracellular PD-L1-Mediated p65 Nuclear Translocation.
Glycogen Hydrogel Loaded with Schistosoma japonicas Peptide SJMHE1 Improves Skin Wound Healing.
Gut microbiota dysbiosis and metabolic abnormalities promote oxidative stress and fibrosis in idiopathic pulmonary fibrosis.
Palmitoylation Induced Activation of SMAD3 Exacerbates Colitis by Promoting Tissue-resident Memory T Cells Differentiation.
The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis.
SC2-3, a Marine Nutrient Glycopeptide from Nereis succinea: Alleviating Cyclophosphamide-Induced Immunocompromise in Mice via M1-Type Macrophage Polarization.
Maternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities.
TIMP3 Suppresses Oxidative Stress and Ferroptosis of Lens Epithelial Cells in Cataract Through Regulating the Keap1/Nrf2 Pathway.
Lentinan mitigates age-related sarcopenia through the promotion of mitochondrial biogenesis.
Tumor Radiotherapy-Induced Sympathetic Hyperactivation Orchestrates Rapid Systemic Bone Loss.
Ketogenic diet alleviates septic lung injury via microbial gut-lung axis.
Pharmacologic and Oncohistone Inhibition of SETD2 Converge on Genomic Instability.
The Avian Influenza Virus PA Protein Recruits Host RPS27A to Support Viral Replication.
The segmented flavivirus ALSV-encoded nucleoprotein VP2 inhibits type I interferon production by targeting RIG-I.
Class-I myosin responds to changes in membrane tension during clathrin-mediated endocytosis in human induced pluripotent stem cells.
LncRNA NORAD Enhances Inflammatory Injury in Sepsis-Associated Acute Lung Damage Through miR-150-5p/STAT1-Dependent NF-κB Activation.
Research based on serine metabolism indicates mesenchymal stem cells alleviate psoriasis by regulating the PSPH-PINK1-Parkin-NLRP3 pathway in HaCaT.
Obesity-associated metabolic dysregulation aggravates myocardial ischemia-reperfusion injury through Gls2-mediated ferroptosis.
Bifidobacterium Pseudolongum-Derived Acetate Attenuates Acute Pancreatitis Through GPR43-Mediated Suppression of M1 Macrophage Polarization.
miR-9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin.
Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Downregulation of B7-H4 contributes to the synergistic effect of USP2a-targeted/anti-PD-1 combination therapy in EGFR mutant lung cancer.
Discovery of Novel HPK1 Inhibitors via Chemistry-Based Direct-to-Bioassay Screening and SAR Optimization.
Syringin Protects Against Doxorubicin-Induced Cardiotoxicity via Apelinr-Dependent Activation of the Nuclear Factor-Erythroid 2-Related Factor 2/Heme Oxygenase-1 Antioxidant Pathway.
GALNT1 emerges as a potential therapeutic target in breast cancer.
Myeloid-Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis.
SETDB2-mediated transcriptional repression of IDE in sensory neurons promotes migraine-like pain behaviors in mice.
Modeling spastic paraplegia 4 with corticospinal motor neuron-enriched cortical organoids reveals genotype-phenotype and HDAC6-targetable pathology.
Targeted inhibition of Nrf2 potentiates antitumor immunity and enhances the efficacy of immunotherapy in hepatocellular carcinoma.
tRF-3005a regulates exon skipping of SPAG4 by interacting with RALY to drive gastric cancer progression.
Matrix Stiffness Modulates Fibroblast Paracrine Signaling to Enhance Autophagy in Keratinocytes: Implications for Wound Healing.
Visinin-like protein 1 disrupts calcium homeostasis and promotes atrial fibrillation in human and rodent models.
Investigation of the effects and underlying mechanisms of adenylate kinase 1 on inosine monophosphate deposition in Beijing-You chickens.
Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Attenuate Secondary Brain Injury After Intracerebral Hemorrhage in Rats by Modulating the SIRT6/Notch1/NF-κB Signaling.
Human Umbilical Cord Mesenchymal Stem Cells Protect Against Steroid-Induced Osteonecrosis of the Femoral Head Through Hippo Pathway.
Ephrin-A4 ligand promotes gastric cancer cell epithelial-mesenchymal transition via the PI3K/AKT signaling pathway.
VISTA promotes ovarian cancer progression through activation of NF-κB pathway and tumor microenvironment reprogramming.
Thioredoxin protects against diabetic hearing loss by regulating TOMM22 mediated mitochondrial autophagy in hair cells and inhibiting microglial M1 polarization.
LncRNA H19 overexpression protects against acute kidney injury after cardiopulmonary bypass via activating Pink1/Parkin-mediated mitophagy.
Mechanotherapeutic Potential of Survivin in Glioblastoma.
UBA1 promotes cardiac hypertrophy by suppressing autophagy via targeting ATG5 for ubiquitination.
Combined Multi-Omics Analysis Reveals the Potential Role of Methionine in Regulating the Proliferation, Differentiation, and Lipid Deposition of Yak Intramuscular Preadipocytes.
Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains.
Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors.
Decoding microglial metabolic cell death and PANoptosis hub genes in subacute phase of traumatic brain injury: a multi-omics and experimental validation study.
PCBP2 mediates MTUS1 degradation through 3'-UTR binding to restrict pyroptosis and augment malignant progression in esophageal squamous cell carcinoma.
Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma.
Zhen-Wu-Tang ameliorates uremic cardiomyopathy via targeting the kidney-heart inflammatory axis and suppressing CCL2/CCR2-mediated macrophage activation.
5-HMF inhibits glucocorticoid-induced osteoporosis through the VEGFR2/PI3K/AKT pathway.
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
CRP Deficiency Rescues Periodontitis-Induced Hippocampal Neurogenesis Impairment by Suppressing OPC-Derived BMP4 Signaling in Rats.
Exploration of the therapeutic potential of magnoflorine against osteoarthritis progression using network pharmacology and in vitro validation.
Electroacupuncture mitigates lung injury, increases endogenous antioxidant levels and modulates Nrf2 signaling in a rat model of chronic obstructive pulmonary disease.
Increased Expression of Connexin 43 Promotes Wnt/β-Catenin Signaling and the Progression of Temporomandibular Joint Osteoarthritis.
Glycine alleviates the intestinal epithelial barrier damage induced by imidacloprid via promoting metabolic detoxification.
Shenqi Granules Enhance Recovery from Myocardial Ischemia-Reperfusion Injury by Downregulating MMP9 and ADH1C.
Fasting-induced physiological remodeling alleviated fatty liver in laying hens through regulating hepatic lipid metabolism.
Programmable genome editing in human cells using RNA-guided bridge recombinases.
Synergistic Anti-Tumor Activity of LRPPRC Inhibition and Dasatinib Through Dual Oxidative Phosphorylation Disruption.
Protein Modifications and Metabolic Alterations in the Rat Striatum Following Oil Mist Particulate Matter Exposure Revealed via Untargeted Metabolomics and Phosphoproteomics.
NRF2 deficiency impairs proliferation and survival of chicken primordial germ cells via oxidative stress, mitochondrial dysfunction and apoptosis.
PHF23-Related Prognostic Signature Modulates Immune Microenvironment and Promotes Tumor Malignancy in Glioma.
Shared molecular signatures between atrial fibrillation and chronic obstructive pulmonary disease: an integrated bioinformatic analysis with experimental validation.
Declined RTN3 stabilizes DHCR7 to induce cholesterol-dependent tumor progression and MEK inhibitors insensitivity in thyroid cancer.
Biological valorization of methane and nitrogen gas-derived ammonia via methanotrophic bacteria for gut-beneficial nutrients.
BEX2 influences the MCL1-Hedgehog signaling axis to regulate the potential of stemness characterization in colorectal cancer.
Congener-resolved hazard identification of ginkgolic acids as emerging natural contaminants.
Puerariae Lobatae Radix-Gastrodiae Rhizoma ameliorates nitroglycerin-induced chronic migraine by modulating p38 MAPK/CREB signaling pathway in the prefrontal cortex-thalamus neural circuit.
Aspartame exacerbates cerebral ischemia-reperfusion injury via mitochondrial dysfunction and ERK/CREB1 pathway suppression.
High fluoride exposure disrupts gut microbiota and induces intestinal barrier damage via RhoA/ROCK-mediated cytoskeletal remodeling.
Paeoniflorin mitigates myocardial hypertrophy by regulating mitophagy and ferroptosis mediated by mitochondria-associated AMPK-Parkin-ACSL4 pathway.
Hyperacetylation escalates myocardial susceptibility to ischemia reperfusion injury by mediating mitochondrial supercomplexes assembly in T2DM.
Butyrate protects against Klebsiella pneumoniae-induced oxidative stress in alveolar macrophages via p62-Keap1-Nrf2 pathway.
Synaptojanin-2-binding protein ameliorates oxidative stress, neuroinflammation and depression-like behaviors via SYNJ2/PIP(2)/IP(3) signaling pathway.
Increased Glycogenin-Exposed Residual Glycogen in Lysosomes Is the Early Pathological Finding in Asymptomatic Pompe Disease.
Deciphering IFN signaling in gastric cancer: A single-cell and bulk transcriptomic integration reveals CXCR4 as a key immunomodulator and prognostic determinant.
CBFA2T3 as a Key Prognostic Biomarker in Lung Adenocarcinoma: Insights from Comprehensive Analysis and Validation.
Estradiol promotes trophoblasts syncytization by upregulating ESR2/SP1 transcription factor-mediated poFUT2 expression.
3D-MSCs apoptotic bodies-integrated conductive hydrogel mitigates spinal cord injury via immunoregulation and alleviating neuronal pyroptosis.
Multi-omics and AI-guided discovery and validation of sisomicin as a COPA-targeting agent for pathological scar inhibition.
Ophiopogonin B inhibits triple-negative breast cancer progression via suppressing PTP1B and regulating the PI3K/Akt pathway.
Hepatotoxicity Mechanisms of Sirolimus and Everolimus Unveiled Through Metabolomics and Transcriptomics Analysis.
Class Effect of SGLT2 Inhibitors Against Doxorubicin-Induced Cardiotoxicity via Regulating Adenosine Kinase Mediated-Cardiac Oxidative Stress.
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Integrated pan-cancer profiling and experimental validation identify CCDC59 as a key driver and therapeutic biomarker in liver hepatocellular carcinoma.
Alpha-ketoglutarate enhances the proliferation and steroidogenic capacities of Tan sheep granulosa cells through autophagy pathway regulation.
Ferroptosis mediates retinal damage caused by the combined effects of sleep deprivation and light damage.
Aldh3a1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to amyotrophic lateral sclerosis progression.
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
Expression of IMD-CBM peptide induces the autophagic degradation of CAV1 (caveolin 1) to inhibit LDL transcytosis and retard diabetic atherosclerosis.
Sympathetic overactivity-induced type H endothelial cell senescence contributes to the impairment of vascularized osteogenesis by PKM2-mediated glycolysis in preclinical stages of Alzheimer's mice.
EGR2 affects mixed stroke repair through BNIP3L-mediated microglial mitophagy.
Revisiting the NETs-CYBB-p38 MAPK axis in bronchiectasis: The underlying oxidative injury mechanism.
Identification of RUNX1 as a Biomarker for Right Ventricular Remodeling in Pulmonary Arterial Hypertension Using WGCNA.
Momordin Ic targets SREBP1 to disrupt lipid homeostasis and trigger synergistic apoptosis-ferroptosis in triple-negative breast cancer.
Brusatol derivative ameliorates rheumatoid arthritis and atherosclerosis with associated suppression of mitochondrial fission.
Tannic acid inhibits viral replication by disrupting nucleocapsid condensation.
Isobavachalcone exerts anti-gastric cancer effects by targeting dihydroorotate dehydrogenase to induce ROS release and activating the STING pathway.
Pterostilbene inhibits ferritinophagy-mediated ferroptosis via the NRF2/NCOA4/FTH1 axis and alleviates intervertebral disc degeneration through nanoliposomal delivery.
A novel METTL3 inhibitor nimbolide ameliorates osteoporosis via orchestrating osteoclastogenesis in an m6A-dependent manner.
Adhesion molecule with Ig-like domain 1 regulates stability of carotid plaque via TGFβ/Smad signaling pathway by interaction with TGFRII.
Exploring the potential of heterocyclic-containing tail approach in the development of novel covalent inhibitors dual-targeting EGFR and HER-2: design, synthesis and biological evaluation.
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
Liraglutide prevents lupus-associated diffuse alveolar hemorrhage via inhibiting lymphocyte infiltration and promoting macrophage M2 polarization.
SiO(2) dust induces the transformation of lung fibroblasts to myofibroblasts by activating the S1P-RhoA-YAP signaling pathway.
Helicobacter pylori infection promotes gastric carcinogenesis by inducing macrophage M2 polarization through the miR-146a-5p/TRAF6 signaling pathway.
Therapeutic mechanism of Changyong Decoction in suppressing colorectal cancer progression and inducing ferroptosis via the PIEZO1-PI3K/AKT signaling axis.
Simiaoyong'an decoction alleviates atherosclerosis by inhibiting adipose tissue inflammation through PPARγ activation: Integrating network pharmacology, molecular docking, and experimental validation.
Structural characterization of a fructan from Kalimeris indica and its efficacy in accelerating wound healing.
A sulfated manno-glucuronan ameliorates β-cell dysfunction in type 2 diabetes by targeting ALDH1A3.
Identification of blood-absorbed components of Qingkui Yuyang decoction and its mechanistic roles in ulcerative colitis based on UPLC-Q-Exactive Orbitrap-MS/MS and network pharmacology.
Ultrasound-guided HUC-MSCs transplantation alleviates neuropathic pain in CCI rats: a mechanistic study based on microglia/macrophage polarization and the NLRP3 inflammasome.
Dimethyl bisphenolate inhibits ovarian cancer growth by regulating the PI3K/AKT/mTOR signaling pathway.
Design, synthesis, and biological evaluation of novel hydrophobic tag-based degraders targeting JNK1.
Epigenetic reprogramming by organic arsenic CZ2 elicits potent antitumor responses in DLBCL through TMS1 restoration.
Tetramethylpyrazine mitigates ER-stress-driven ATF4/CHOP apoptosis to protect dopaminergic neurons in cellular and MPTP models of Parkinson's disease.
Beneficial effects of electro-acupuncture treatment in photothrombotic ischemia model rats by remodeling neurovascular unit.
High-throughput RNA sequencing identifies hub genes and anti-inflammatory effects of β-caryophyllene in cerebral ischemia-reperfusion via p38MAPK/NF-κB modulation.
Ginkgolide B alleviates cerebral ischemia-reperfusion injury by antagonizing TRIM45 to reduce microglia-mediated neuronal damage.
Hippocampal AIM2 inflammasome regulate seizure and cognitive impairment in mice with temporal lobe epilepsy.
Spinal cord injury-derived exosomes exacerbate damage: miR-155-5p mediates inflammatory responses.
Hydrogen sulfide ameliorates peritoneal fibrosis: inhibition of high mobility group box-1 expression to block the activation of the transforming growth factor-beta/Smad3 pathway.
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
Mitochondria-targeting iridium(III) complex enhances anticancer activity via PDK inhibition and energy metabolism disruption.
Porcine-derived amelogenin P148 in a layer-by-layer chitosan/hyaluronic acid coating for enhanced implant osseointegration.
Bisphenol A exposure disrupts the circadian clock system and impairs glycolipid metabolic function in mice liver.
From palmitoylation to cholesterol metabolism: The hidden mechanism of lung tumorigenesis.
The mechanism of depression and anxiety in adulthood after experiencing early adverse experiences: A new two-hit model of depression.
Protective effects of the ethyl acetate fraction from Madeng'ai on lipopolysaccharide-induced acute lung injury in mice: Insights from integrated multi-omics analysis.
Methyl 3-chloroasterric acid exerted anti-neuroinflammatory and antidepressant effects through the downregulation of P2Y1R.
Characterization of a polysaccharide from Rhodobryum giganteum and its activation effects on TLR4/PI3K-Akt/IκBα pathway.
The role of the IL-33/ST2/MAPK signalling pathway in macrophage polarisation and endometrial fibrosis.
Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation.
MG53 protects against septic cardiac dysfunction by ubiquitinating ATF2.
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation.
Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach.
Single-Nucleus Transcriptomics Uncovers Xaf1-Driven PANoptosis as a Therapeutic Target in Aminoglycoside-Induced Hearing Loss.
YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice.
From Cells to Animals: Connexin43 Suppression Enhances Autophagic Flux to Restore Odontogenesis in Inflamed Dental Pulp.
METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner.
S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition.
GATA3-NLRP1 Axis Inhibits Hepatocellular Carcinoma Progression Through the Hedgehog Signaling.
The oncogenic role of NSUN2 in lung adenocarcinoma by stabilizing CCT5 mRNA via a YBX1-dependent m5C modification.
Multimerin-1 modulates macrophage M2 polarization and enhances tumor cell stemness in glioblastoma.
ALYREF condensation stabilizes m(5)C-modified PARP10 mRNA and promotes PI3K-AKT signaling in ovarian cancer.
Complement C3a Suppresses Spinal Cord Neural Stem Cell Activation by Inhibiting UCHL1 via the NF-κB p65/Nrf2 Pathway.
Lopinavir/ritonavir induces hepatotoxicity in HepG2 cells through inhibition of the Nrf2 pathway, resulting in oxidative stress, endoplasmic reticulum stress, and cell cycle arrest.
The role of FOXO1/PPARγ in atrazine-induced hepatic lipid metabolism disorders.
Piperine Inhibits the Immune Checkpoint CD47 to Enhance Immunity Against Pancreatic Cancer.
Structural characterization and multi-omics analysis of novel Saposhnikovia divaricata (Turcz.) Schischk acidic heteropolysaccharide alleviating acute liver injury.
UBA5 missense variants disrupt UFM1 activation: Structural, dynamic, and functional dissection.
Immunological activity of peach pectins: Insights from cells to animals.
Yigu Decoction polysaccharides mediate gut microbiota and metabolites to promote bone formation-related protein expression and improve osteoporosis.
Histone deacetylase 6 deacetylates and ubiquitinates ATG3 to regulate autophagy.
TRIM32 promotes anoikis resistance and metastasis in NSCLC by degrading CHEK2 to enhance IL-6 secretion.
Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications.
Topology scaffolds-enhanced paracrine of BMSCs through mechanotransduction-related metabolism reprogramming for burn wounds healing.
Cadherin 11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit.
Rab2A modulates liver fibroblast growth factor 21 (FGF21) expression and systemic metabolism via apolipoprotein B-CREBH signaling.
Integrin β4 drives immune evasion and therapeutic resistance to PD-1 blockade in bladder cancer via MEK/ERK signaling.
Lysine demethylase 4A is a centrosome-associated protein required for centrosome integrity and genomic stability.
White kidney bean extract improves letrozole-induced polycystic ovary syndrome in rats by regulating the Wnt signaling pathway.
Myeloid-Derived CD38 Mediates Age-Related Endometrial Aging Through NAD(+) Depletion.
Poly (allylamine hydrochloride)-selenium nanoparticles inhibit porcine reproductive and respiratory syndrome virus by targeting DDX5 and reactive oxygen species.
Hesperadin sensitizes gastric cancer cells to cisplatin via NOX1-dependent oxidative stress.
Effects of repetitive transcranial magnetic stimulation on apoptosis and MAPK/PI3K-AKT signaling pathways in rats with spinal cord injury.
Sesamin exerts protective effects against diquat-induced acute kidney injury by inhibiting oxidative stress, apoptosis and autophagy: A key role for the SIRT5/FOXO3a signaling pathway.
Poria cocos polysaccharide inhibits Porcine Deltacoronavirus replication in vitro through regulating apoptosis by PI3K-Akt/NF-κB signaling pathway.
Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged mice.
Japanese encephalitis virus activates the NLRP3/caspase-1/GSDMD signaling pathway in dopaminergic neurons.
Acacetin Alleviates Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease in Mice by Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis.
DNA Methylation Patterns of 5mC Regulators: Insights into Immune Microenvironment Regulation in Heart Failure.
Linoleic acid promotes osteogenic differentiation of bone marrow mesenchymal stem cells and ameliorates ovariectomy (OVX)-induced osteoporosis in mice through the PI3K/AKT pathway.
Isoimperatorin inhibits cell proliferation and induces apoptosis via regulating PI3K/AKT pathway in acute lymphoblastic leukemia.
COA6 deficiency inhibits hepatocellular carcinoma progression by regulating cuproptosis through the JAK/STAT signaling pathway.
Mechanical stress accelerates vascular calcification by Piezo1/BMP2 of vascular smooth muscle cells.
M1 macrophages enhance breast cancer chemoresistance via JAK-STAT3 signaling.
Corneal biomechanical cues mediated by PAI-2: the origin of PM2.5-induced corneal disease.
METTL1-mediated m7G methylation of FoxO1 regulates lipid metabolism in metabolic dysfunction-associated fatty liver disease.
Targeted demethylation of the BRD7 promoter based on CRISPR/dCas9 system inhibits the malignant progression of nasopharyngeal carcinoma.
Melatonin-engineered MSCs-exosomes deliver USP4 to stabilise ARNTL and inhibit clock rhythmic ferroptosis for enhanced flap survival.
NIR-Triggered Metal-Polyphenol Nanoparticles Enhance HPV-Driven Cancer Immunotherapy via Immunogenic Cell Death and STING Sequential Activation.
A Galactose-Engineered Dual-Responsive Nanocarrier for ASO/CRISPR-Cas9 Delivery to Inhibit HBV Replication.
Autocrine TGF-β1 in Periodontal Ligament-Derived Stem Cell Pellets Enhances Periodontal Regeneration in Class II Furcation Defects of Canine Models.
Batatasin III alleviates slow transit constipation by regulating gut microbiota and inhibiting the NLRP3-IL-1β pathway.
Red nucleus IL-15 facilitates the development of neuropathic pain in male rats by inducing inflammatory factors: implying the involvement of NF-κB and p38 MAPK.
Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury.
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
NUSAP1 Recruits DAXX to Suppress HIF-Driven Triple-Negative Breast Cancer Progression.
Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X-Linked Hypophosphatemic Rickets.
Investigation into the Pancreatic Pathogenesis of SFTSV across Multiple Levels.
EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non-Small Cell Lung Cancer via Hippo Pathway Activation.
Site-Specific Mitochondrial RNA N1-Methyladenosine Demethylation via an Engineered MTS-PUF-ALKBH3 Fusion Protein.
Pharmacological Enhancement of Integrated Stress Response Confers Protection in Calcific Aortic Valve Disease.
A model of coagulation-related genes for prediction of prognosis in lung adenocarcinoma and verification in vitro.
Morin improves postoperative cognitive dysfunction by mediating the miR-138-5p/SIRT1 axis to regulate ferroptosis.
Impaired nitrogenous waste clearance promotes hepatocellular carcinoma.
RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria.
Exosomes derived from ADSC suppress endothelial cells ferroptosis and alleviate sepsis acute liver injury via regulation of Keap1/Nrf2/GPX4 axis.
Acupuncture ameliorates diet-induced obesity via the vagal-GLP-1-ARC circuit: neural mechanism of anorexigenic action.
Ferulic acid in combination with ginsenoside Rb1 alleviates myocardial no-reflow by inhibiting platelet HMGB1 release and NET formation.
NAT10-mediated ac4C modifications regulate glioblastoma progression.
Phase 1 dose-escalation trial of sub-endometrial injection of human embryonic stem cells-derived immunity-and-matrix-regulatory cells to promote endometrial angiogenesis in refractory intrauterine adhesion.
Methotrexate-triggered ferroptosis suppresses oral cancer progression by phosphorylated KEAP1-mediated NRF2 degradation to inhibit SLC7A11/GPX4 signaling pathway.
Spinal astrocytic EAATs mediate endothelin-1-induced breakthrough cancer pain in mice.
CD36 as a potential prognostic biomarker and modulator of the tumor microenvironment in glioma.
Simvastatin Alleviates ConA-Induced Autoimmune Hepatitis by Inhibiting CD4(+) T Cell Activation via Calcium-NFATC3 Pathway.
Artemisinin-hydroxychloroquine combination from traditional antimalarial medicine attenuates pulmonary fibrosis via PI3K/AKT/GSK3β-mediated inhibition of epithelial-mesenchymal transition.
Fuxin decoction regulates the Nrf2/SLC7A11/GPX4 pathway to ameliorate doxorubicin-induced ferroptosis in cardiomyocytes.
Chrysanthemum morifolium Ramat. water extract prevents and treats metabolic-associated fatty liver disease via pan-PPAR activity.
Neuronal Subtype-Specific Expression of γ-Enolase: Its Role in Neuronal Differentiation.
The METTL3-IGF2BP3 axis drives osteosarcoma progression by enhancing ID1 mRNA stability.
Acrylamide disrupts meiotic G2/M transition and SAC activity during oocyte maturation.
α-terpineol induces apoptosis in melanoma cells and its underlying mechanism.
PiR48444 inhibits MSC osteogenic differentiation and bone regeneration via targeting METTL7A/eIF4E-mediated BMP2 m6A methylation.
Targeting glucocorticoid receptor to enhance immunotherapy response in triple negative breast cancer.
BPC157 drives angiogenesis through FBXO22-dependent stabilization of BACH1.
Role of p38 MAPK in the cytokine reprogramming of a human leukemic cell line with a drug-resistant phenotype.
Quercetin alleviates LPS-induced inflammatory response in dairy cow lamellar keratinocytes through PI3K/Akt/NF-κB signaling pathway.
IL-4/Nanohydroxyapatite Codelivery in a Dual-Bionic Scaffold: Design and Immunomodulatory Endogenous Osteogenesis Mechanism.
Systematic evaluation of mitochondrial morphology regulators for amelioration of neuronal α-synucleinopathy.
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway.
Cyclin D1/D2-CDK4 Drives Cell Migration by Orchestrating Cytoskeletal Dynamics Through a TGFβ-FAK-Rac1 Axis.
HAGLR promotes endometriosis progression via the miR-185-5p/VEGFA axis and serves as a potential diagnostic biomarker.
Construction and Biological Characterization of ORF133-Deletion Mutant of Lumpy Skin Disease Virus.
Essential role of NONO-HOXA1-Wnt axis in cardiomyocyte differentiation.
A paraventricular hypothalamic control of social stress susceptibility by targeting brown adipose tissue β3 adrenoceptor.
Structural basis of co-translational N-myristoylation in humans.
Loss of Epithelial Homeostasis Driven by TMBIM1 Depletion via E-Cadherin Junction Disassembly.
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
Vasicine Attenuates Allergic Asthma by Suppressing Mast Cell Degranulation and Th2 Inflammation via Modulation of the FcεRI/Lyn + Syk/MAPK Pathway.
Nuclear activities and interactome of the NS5 protein of Tick-Borne Encephalitis Virus.
Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer.
The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis.
VILMIR is a trans-acting long noncoding RNA that enhances the host interferon response in human epithelial cells.
MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
METTL3-mediated m(6)A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca(2+) signaling.
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
PRSS23 promotes pancreatic cancer progression through regulating Hippo-YAP activity.
CNOT3 resists ovarian aging by accelerating oocyte maturation and promoting ESCs differentiation.
MARCHF1-mediated SULF1 degradation blocks THBS2/TGF-β/SMAD2/3 signaling to reverse colon cancer metastasis and 5-FU resistance.
Partial embryo loss caused by disruption of the placental hormone CTRP6 coincides with dNK cell abnormalities during pregnancy.
Targeted PGC-1α gene delivery by GV-assisted ultrasound cavitation for renal ischemia-reperfusion injury therapy.
A causal coding variant regulating alternative splicing of DOC2A at 16p.11.2 GWAS locus influences susceptibility to schizophrenia.
Chitinase-3-like protein 1 depletion in glioma cells alters tumor microenvironment and normalizes neovasculature in human glioma xenografts.
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
IL-24 ameliorates cognitive dysfunction via the inhibition PERK-eIF2α Signaling pathway in Alzheimer's disease.
DXFD-1 alleviates DSS-induced ulcerative colitis by targeting NF-κB and Nrf2 signaling.
S-nitrosylation of IRF7 induced by NOS1 expression in melanoma suppresses anti-tumor immunity.
Crystal structure of Echinococcus multilocularis cystatin B reveals a novel feature in classical stefins.
Multi-omics analysis identifies BUB1B as a cell cycle-related driver of bladder cancer progression.
IL-25-ILC2-IL-13 axis improves traumatic brain injury by mediating CXCL-10-dependent regulation of blood brain barrier integrity.
Atypical tetracyclines promote longevity and ferroptotic neuroprotection via translation attenuation.
Huashi Baidu granules alleviates LPS-induced acute lung injury by targeting TACE-mediated inflammatory signaling and stress granules disassembly.
The renoprotective anti-hyperuricemia effect of Cornus officinalis extract in hyperuricemia rats based on network pharmacology and multiple omics.
Decoding the healing secrets of Gegenqinlian decoction: A promising approach to radiation-induced intestinal injury.
Disruption of zinc homeostasis reduces histone acetylation levels in normal and tumor cells.
PHB1 Attenuates Triptolide-induced Cardiotoxicity by Regulating Mitochondrial Dynamics in Cultured Newborn Mice Cardiomyocytes.
UDP-glucuronosyltransferase 1A9 function is mediated by the two C-terminal lysine residues and proper mobility/flexibility of the cytoplasmic tail.
Curzerene Ameliorates Depression-Like Behaviors and Cognitive Impairment by Modulating the Gut Microbiota and HMGB1/RAGE/TLR4 Pathway.
Inhibition of the PI3K/AKT signaling pathway blocks the oncogenic activity of TRIM26 in prostate cancer cells.
Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood-brain barrier.
Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress.
Mechanism of Atractylodis Rhizoma in improving cognitive dysfunction in Alzheimer's disease by regulating the cAMP/CREB/BDNF pathway.
Inhibition of neutrophil infiltration and NETosis ameliorates sepsis-induced cardiac injury and reduces myocardial inflammation and apoptosis.
Macrophage-specific UBA1 knockout attenuates sepsis-induced liver dysfunction by regulating inflammatory responses via the BMAL1/CLOCK-REV-ERBα axis.
BNIP3-mediated mitophagy alleviates traumatic brain injury by inhibiting neuronal apoptosis and oxidative stress.
Polyethylene terephthalate microplastics exposure enhances the risk of ulcerative colitis: insights from multiomics integration, machine learning, and molecular docking reveal intestinal toxicity mechanisms.
Integrated analysis of bulk RNA and single-cell RNA sequencing data reveals potential biomarkers and immune infiltrates associated with N7-methylguanosine in osteoarthritis.
Elucidating the causal effects of plasma metabolites on breast cancer from multiple perspectives.
Asiatic acid reverses cisplatin resistance in A549/DDP cells by activating the P38 MAPK/Slug pathway.
Targeting mesenchymal monocyte-derived macrophages to enhance the sensitivity of glioblastoma to temozolomide by inhibiting TNF/CELSR2/p65/Kla-HDAC1/EPAS1 axis.
PTPN22 as a therapeutic target in intervertebral disc degeneration: Modulating mitophagy and pyroptosis through the PI3K/AKT/mTOR axis.
SA supplementation during lactation promotes learning and memory by reducing H3K27me3 levels.
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries.
The Deubiquitinating Enzyme USP46 Abolishes Cell Survival of Prostate Cancer via Enhancing BECN1-Dependent Autophagy.
Characterizing Chemokine Signaling Pathways and Hub Genes in Calcium Oxalate-Induced Kidney Stone Formation: Insights from Rodent Models.
Mitochondrial Function Is Required to Preserve Viability of Stem Cells From the Apical Papilla Following Porphyromonas endodontalis Infection.
Single-immunocyte transcriptomics reveal the role of natural killer cell-dependent exogenous antigen presentation in ankylosing spondylitis severity.
Piezo1 activation in endothelial cells aggravates microvascular ischemia-reperfusion injury in limbs by enhancing ferroptosis.
Aberrant miR-378 expression promotes hepatic lipid accumulation via hijacking the bile acid-regulated autophagy.
Deletion of hepatic growth hormone receptor contributes to the pathogenesis of lean MAFLD by elevating CD36.
The Virulence-Associated CAP/PR1-Like Proteins From Cytospora chrysosperma Target a Subunit of RNA Polymerase II to Suppress Plant Immunity.
Diagnostic potential of neutrophil extracellular traps in ulcerative colitis: a gene-based predictive model.
Neuroprotective effects of dexmedetomidine in spinal cord injury via modulating PERK/ATF4 pathway.
Effects of Piperine on Obese and Lean Nonalcoholic Fatty Liver Disease in Mice.
Integrating UPLC-HR-MS, network pharmacology and experimental validation to reveal the potential mechanism of Fuzheng Bixie granules in treating acute lung injury.
Network pharmacology, molecular docking, molecular dynamics simulation, and in vivo experiments elucidate the potential mechanisms of berberine against liver injury.
Piezo1 mediated scaffold-free rapid generation of self-mineralized bone organoids via activating Wnt signaling.
CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation.
Subcellular distribution of Prussian blue nanozymes dictates enzymatic activity and macrophage polarization for effective colitis therapy.
Enhanced osteointegration of implants in aged rats via a stem cell pool aging reversion strategy.
Hydrogen-Mediated Activation of the Nrf2/HO-1 Signaling Pathway Improves Cognitive Impairment in Sleep-Deprived Mice.
A prognostic model for human papillomavirus-negative head and neck squamous cell carcinoma based on a novel ferroptosis-related gene signature: Development, validation and elucidation of its relationship with the immune microenvironment.
Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer.
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury.
Bawei Chenxiang Pills Exert Anti-Myocardial Ischemia Effect by Inhibiting Inflammation Through the TLR4/NF-κB/NLRP3 Signaling Pathway.
Crustacean Mab21 proteins drive tissue-specific antiviral immunity by activating IKKε outside the canonical nucleic-acid sensing paradigm.
Cell death modulation dictates tissue-specific tropism of lumpy skin disease virus.
Oncometabolite 5-IP(7) inhibits inositol 5-phosphatase to license E-cadherin endocytosis.
Exosomal FOSL1 From Cancer-associated Fibroblasts Drives the Progression and Pro-tumorigenic M2 Macrophage Polarization of Hepatocellular Carcinoma By Activating PLAU Transcription.
An explainable predictive machine learning model reveals ARRB2 as a key gene in post-traumatic stress disorder: A GEO database study.
Integrated bioinformatics and machine learning analysis identify CROT as a regulator of immunological features in idiopathic pulmonary fibrosis.
Exploring the relationship between gut microbiota-metabolite axis and Jiawei Danxuan Koukang's therapeutic effects in male rats with oral submucous fibrosis: A multi-omics analysis.
Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini-chromosome maintenance complex and causes DNA damage.
COL1A1 promotes clear cell renal cell carcinoma progression through the Wnt/β-catenin signaling pathway.
CUEDC2 improves pyroptosis and kidney damage in diabetic kidney disease by inhibiting NLRP3 inflammasome activation.
Notoginsenoside R1 as a Protector Against Gentamicin Ototoxicity: Targeting p62-NRF2-GPX4 Ferroptosis Axis.
Environmentally relevant lanthanum chloride exposure induces hepatic steatosis in zebrafish larvae via PPARα-dependent ApoB suppression.
LncRNA AC098613.1 promotes acute myeloid leukemia cell differentiation through CDC5L/ADAP1/NRD1 axis.
ZP3 promotes hepatocellular carcinoma progression via the Notch signaling pathway and is associated with the tumor microenvironment and immunotherapy response.
Wnt/β-Catenin Activation by iCRT3 Enhanced the Pluripotency of Bovine Expanded Pluripotent Stem Cells.
Liver-muscle metabolic crosstalk: xanthosine as a key effector of broiler myogenesis.
Danggui-Baishao herb pair protects against dextran sulfate sodium-induced colitis by modulating the Wnt/β-catenin pathway.
FSHR-targeting tetrahedral DNA frameworks ameliorate ovarian aging through oxidative stress elimination.
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Antitumor efficacy and molecular mechanism of lenvatinib combined with vitamin K2 against hepatocellular carcinoma.
Molecular basis of collagen galactosylation by GLT25D1.
Comprehensive Proteomics and β-Hydroxybutyrylation Profiling in Starvation-Induced Gastrocnemius Muscle Remodeling.
Single-cell profiling reveals pervasive heterogeneity in subcellular RNA localization.
Discovery of novel small molecule inhibitor targeting the tumor promoting effect of transcription factor PLAGL2.
Chicory Extract Alleviates Anthracycline-Induced Cardiotoxicity by Inhibiting Mitochondrial Damage via the UCP2/NLRP3 Pathway.
Astrocytic CCL5 orchestrates CCR5-positive neuronal necroptosis in subarachnoid hemorrhage.
Absence of Neuromuscular Dysfunction in Mice with Gut Epithelium-Restricted Expression of ALS Mutation hSOD1(G93A).
Targeting Hsp70 triggers ferroptosis: a novel anti-cancer mechanism of a marine natural product in prostate cancer.
Uncovering a Glaucoma-Linked Lysophosphatidic Acid-MAPK/AP-1 Fibrosis Axis in Human Trabecular Meshwork Cells and Its Modulation by Diospyros kaki Leaf Extract.
EP300 promotes hepatocellular carcinoma proliferation, migration and in vivo tumorigenicity revealed by integrated experimental and bioinformatic analyses.
Macrophage-Mimicking Biomimetic Microbubbles for Early Ultrasound Molecular Imaging of Acute Rejection in Heart Transplantation.
Dysregulated expression of the tumor suppressor p14ARF in cancer provides an effective target for TCR-T cell therapeutics.
SMYD3 synergises with RACK1 to promote colorectal cancer lung metastasis by recruiting SMAD3.
Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics.
The Mislocalization of TDP-43 to Mitochondria Impairs Myotube Maturation.
Resveratrol and AG490 Overcome Glioblastoma Cells' Resistance to Monotherapy by Inhibiting JAK2/STAT3 Signalling Pathway.
Combinatorial treatment with donafenib and quercetin suppresses lipid metabolism in HepG2 cells by targeting the CREB1/DRP1/SREBP1 axis.
Identification and validation of a novel estrogen-related model for breast cancer to predict the prognosis.
LncSMIM14 Hijacks Rab3a-Mediated Endocytosis to Promote Bovine Viral Diarrhea Virus Replication.
UHRF2 related to sumoylation : assessment of its role in immune suppression and therapeutic potential in colorectal cancer.
Matrix Metalloproteinase 7 Mediates Epithelial-Mesenchymal Transition to Promote Liver Fibrosis Through E-cadherin/β-catenin Pathway in Biliary Atresia.
Synergistic Effects of Nutritional Formula on Joint Inflammation Through Modulation of Bone Metabolism in Rats.
DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312.
USP30-AS1 functions as a post-transcriptional amplifier of interferon signalling to drive autoimmune pathogenesis.
Enolase 1 suppresses influenza A virus replication by blocking the nuclear import of the viral ribonucleoprotein complex.
The SIRT1-Mediated p53 Deacetylation Pathway Modulates Apoptosis and Promotes Viral Replication in MVC-Infected Cells.
Irisin inhibits adipogenic differentiation of bone marrow mesenchymal stem cells through the SIRT1/RANBP2/FTO signaling axis and protects against osteoporosis.
Triptonide Suppresses AML via PI3K/AKT Signaling: A Network Pharmacology Approach Validated by Molecular Docking and Experimental Studies.
Identifying the hub genes in macrophage infiltration and verifying of the role of VSIG4 in IgA nephropathy.
PDHA1 enhances resistance to ferroptosis in anoikis-resistant prostate cancer by upregulating AIFM2.
Multi-omics analysis reveals RBPJ-mediated regulation of EGF/ACTN2/MYPN/COL21A1 in fibroblast during oviduct functional remodeling of duck.
[Xuebijing Injection in synergy with linezolid alleviates inflammatory injury in mice with MRSA pneumonia by inhibiting the Hla-NLRP3 pathway].
Transcriptomics and functional genomics implicate WNT3 in hemispheric lateralization of speech production.
ACTG1 facilitates proliferation and epithelial-mesenchymal transition-mediated metastasis via COL21A1 in gastric cancer.
p300 upregulates I kur in atrial cardiomyocytes through activating NLRP3 inflammasome in hypertension.
Radix Rehmanniae Preparata polysaccharide promoted zebrafish heart regeneration by activating the IFN-γ/NF-κB signaling axis.
Research on the mechanism of CRMP4-mediated cytoskeletal actin polymerization in promoting invasive migration of stromal cells in endometriosis.
Growth differentiation factor 15 promotes the malignant progression of multiple myeloma via activation of PI3K/Akt/NF-κB signaling pathway.
VDAC1 protein derived from extracellular vesicles promotes paclitaxel resistance in gastric cancer through autophagy and mitophagy.
CircRNA-TMEM71 Inhibits Human Aortic Smooth Muscle Cell Ferroptosis and Prevents Aortic Dissection Formation Through IGF2BP3-Mediated Stability of FSP1.
IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer.
Marine trichodermamide B inhibits prostate cancer progression via catalase inhibition-induced apoptosis.
Cu(OH)(2) nanopesticide induced adolescent social behavior deficits via long noncoding RNA-mediated synaptic network dysfunction.
USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression.
Y chromosome-linked EIF1AY deletion drives sex differences in multiple myeloma.
Metamorphosing macrophages promote placental fibrosis by upregulating the transcription factor STAT5A.
African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation.
Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression.
Targeting ADAMTS1/HDAC6 alleviates TGF-β1/SMAD2-associated cardiac fibrosis in cardiac fibrosis post-myocardial infarction.
Supplemental exposure to polystyrene nanoplastics synergistically amplifies calcium oxalate crystal-induced injury to renal tubular epithelium, accelerating the formation of calcium oxalate kidney stones.
Fungal-Bacterial Crosstalk Modulates Glucocorticoid-Primed TLR2 Signaling in the Human Skin.
Self-assembling ferritin nanoplatform enables amyloid-β-targeted immunotherapy and cognitive rescue in APP/PS1 mice.
A CDK-4EBP1 signaling axis drives HSV-1 replication and underscores a druggable pathway for potent antiviral intervention.
Gasdermin B-mediated pyroptosis as a host defense against swine enteric coronaviruses and its antagonism by PEDV.
Early HMGB1 Inhibition Reduces Hippocampal Injury During Adolescence in a Young Mouse Model of Radiation-Induced Brain Injury.
PUF, a biflavone monomer, triggers DNA damage through SLC25A15 downregulation and purine metabolic suppression in DLBCL.
Importin Alpha Is Implicated in the Nuclear Import of Novel Duck Reovirus Protein p18.
LSKL mitigates dehydroepiandrosterone-induced apoptosis and oxidative stress by THBS1/PI3K/AKT pathway in rat granulosa cells.
Adiponectin Receptor 1-vascular endothelial growth factor axis mediates resistance to epidermal growth factor receptor-targeted therapy in nasopharyngeal carcinoma.
Botulinum neurotoxin A alleviates Deinagkistrodon acutus venom-induced limb injury through promoting macrophage polarization in rabbits.
Pregnane X receptor mitigates aristolochic acid-induced acute kidney injury via p53 ubiquitination.
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
LncRNA UNC5C-AS1 inhibits angiogenesis and induces endothelial apoptosis via the miR-148a-3p/EMP1 axis in preeclampsia.
HIV-1 Vpr activates microglia by upregulating m6A modification through ubiquitin-proteasome pathway-mediated degradation of the demethylase ALKBH5.
Super-enhancer-associated miR-1260b coordinates adipogenesis and metabolic programming in human adipose stem cells.
Gut microbiota dysbiosis exacerbates acute pancreatitis via Escherichia coli-driven neutrophil heterogeneity and NETosis.
Engineered extracellular vesicles from human placental mesenchymal stem cells attenuate abdominal aortic aneurysm formation by inhibiting Nat10-mediated vascular smooth muscle cell senescence.
Organelle stress in pyometra: Molecular evidence of endoplasmic reticulum stress and mitochondrial dysfunction.
PHC2 promotes hepatocellular carcinoma progression and serves as a robust prognostic biomarker: A pancancer multiomics and clinical validation study.
B4GALT1 drives osteoarthritis progression by stabilizing IL-1R1 through N-linked glycosylation.
KLK8 promotes cartilage degradation and pyroptosis in osteoarthritis by activating the NF-κB and NLRP3 inflammasome pathways.
Diosgenin alleviates hepatic fibrosis via PI3K/Akt/mTOR mediated fatty acid metabolic reprogramming and NF-κB activation.
Aberrant histone acetylation and dysregulated synaptic plasticity in cognitive impairment induced by a high-methionine diet.
Integrated multi-omics analysis identifies potential therapeutic targets for Alzheimer's disease.
Shh-S100A10 axis curbs neuronal PANoptosis after ischemic stroke.
Quercetin targeted NF-κB to regulate platelet activation and prevent arterial thrombosis.
Three-dimensional cell culture in vitro could better recapitulate the biological behavior of cells in vivo.
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
MFG-E8 prevents M1 macrophage polarization to alleviate osteoarthritis by inhibiting NLRP3 inflammasome.
USP16 promotes M2 polarization of macrophages in colorectal cancer by activating the Notch pathway via inducing the deubiquitination of E2F1.
Anacardic Acid Inhibits Pde2a to Enhance Colonic Epithelial Barrier Integrity in the Improvement of Diabetic Cardiomyopathy.
Construction and validation of golgi apparatus-related genes as predictors of the immune microenvironment and prognosis in colorectal cancer.
TMEM44 as a Novel Prognostic Marker for Hepatocellular Carcinoma is Associated with Tumor Invasion, Migration, and Apoptosis.
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
A Novel Telomere Maintenance Gene-Related Model for Prognosis Prediction in Gastric Cancer.
Oncogenic role and potential mechanisms of MYO1B in breast cancer.
The glycolytic metabolite phosphoenolpyruvate restricts cGAS-driven inflammation to promote healthy aging.
Soluble Sema4D From γδ T Cells Exerts Osteoblast Inhibition via Plexin-B/mTOR Signalling Contributing to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws.
An intelligent nanoliposome alleviates disc degeneration and discogenic pain by inhibiting neurovascular ingrowth via a "Soil-conditioning, seed-modulating, and weeds-suppressing" strategy.
POSTN(+) fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling.
MRPL42 Knockdown Suppresses the Malignant Functions of Hepatocellular Carcinoma by Regulating Oxidative Phosphorylation.
UXS1 Knockdown Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma by Inducing Ferroptosis via SLC7A11/GPX4 Pathway.
KAT8: A Promising Biomarker for the Prognosis of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure.
NUPR1 and LCN2: Potential Therapeutic Targets for Colorectal Cancer Via Modulating Cell Viability, Migration, and Ferroptosis-Related Pathways.
Graphene oxide coating on two-dimensional glass substrates and three-dimensional zirconia scaffolds for bone tissue regeneration.
Biomimetic cancer cell membrane-coated liposomal nanocarriers loaded with silibinin suppress gastric cancer progression via SNHG1/miR-383-5p/HSP90AA1 axis-mediated PI3K/AKT pathway inhibition.
CircRNA SLAIN1 is associated with reduced malignancy progression of glioblastoma and the M2-like polarization of tumor-associated macrophages via miR-1225-3p/NLRX1 axis.
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Dynamic regulation of K33- and K48-linked ubiquitination of Tip60 by TRIM37 orchestrates host DNA damage response during Pseudomonas aeruginosa infection and recovery.
Landscape of splicing factors in early-onset gastric cancer reveals SRSF1 as a key driver of oxaliplatin resistance.
Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4-Mediated Ferroptosis.
FTO mediates m6A demethylation of HNF1A and drives hepatic steatosis in metabolic dysfunction-associated steatotic liver disease.
Lactobacillus plantarum 1-2-3 Ameliorates the Corticosterone-Induced Fatty Liver Hemorrhagic Syndrome in Laying Hens by Biosynthesizing Gamma-Aminobutyric Acid.
Inhibitory effect of Anwulignan on the IL-36R/TLR9 signaling pathway: potential therapeutic role in hepatic fibrosis.
Dingxin recipe Ⅲ ameliorates atherosclerosis through stard4-mediated regulation of hepatic lipid metabolism.
3,3'-Diindolylmethane ameliorate obesity-related skeletal muscle atrophy via regulating mitochondrial function.
ANKRD62 Modulates NF-κB Signaling to Promote Proliferation and Migration in UCEC.
Cockroach-Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation.
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis.
Non-Targeting shRNA-Encoded Plasmid DNA Enhances Protective Immunity Through RIDD-RIG-I Signaling Pathway in the Zika Virus Animal Model.
Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism.
Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression.
GATA6 inhibits the periodontitis progression through regulating the Notch signaling pathway.
Regulation of skeletal muscle development and metabolism in broiler chickens by Urolithin A through threonine kinase 1 pathway activation.
Discovery, Optimization, and Biological Evaluation of 2-Cyano-2-(9H-xanthen-9-ylidene)acetamide Derivatives as ZNF207 Inhibitors for Anti-Glioma Therapy.
Amentoflavone mitigates UVB-induced epidermal photoaging by antagonizing PAR2-driven PI3K/Akt/FoxO6 oxidative-stress signaling.
SEMA4A promotes acute myeloid leukemia progression through inhibiting apoptosis.
Vps34 Knockdown Alleviated the Long-Term Effect of Nano-Alumina on Cognitive Impairment in Zebrafish When in Embryos.
Noncanonical open reading frames from lncRNAs encode functional micropeptides that help shape agronomic traits in rice.
Zuojin Pill ameliorates depression with gastrointestinal dysfunction via Parabacteroides distasonis.
O-GlcNAc Modification Orchestrates HUWE1-Mediated Ubiquitination of TfR1 to Regulate Ferroptosis and Trophoblast Syncytialization in Preeclampsia.
An Activity-Dependent NEPAS-PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment.
Mechanisms of Mechanical Stress-Induced Vascular Remodeling via the Lactate-PKM2 Axis and Implications for Microgravity Adaptation.
Baicalein alleviates Alzheimer's disease pathology in AD models by activating the PI3K/AKT/GSK3β pathway to inhibit neuronal apoptosis.
Identification and Screening of Lactate-Related Genes as Molecular Markers for Early Diagnosis of Steroid-Induced Osteonecrosis of the Femoral Head.
Integration of Single-Cell RNA Sequencing and Machine Learning to Identify and Validate Prognostic Genes With Lymph Node Metastasis and Immune Cell Signatures in Lung Adenocarcinoma.
Chemical-Assisted Ligation-qPCR for Locus-Specific Detection of RNA N(4)-Acetylcytidine and 5-Formylcytidine.
Vasoactive intestinal peptide attenuates form-deprivation myopia in guinea pigs by suppressing the Wnt/β-catenin pathway along the retina-choroid-scleral axis.
Brucea Javanica Oil Attenuates Osteosarcoma Progression by Reprogramming Tumor-associated Macrophages via Inhibiting PI3K/AKT Pathway.
OLFM4 mediating ischemia/reperfusion-induced kidney injury by regulating renal tubular epithelial cells ferroptosis via GPX4.
Mesenchymal stem cells derived EXO-miR3671 delivery promoted angiogenesis and accelerated wound healing of diabetes.
Engineered CAR-monocytes coordinate fibrosis clearance and cardiac regeneration following myocardial infarction.
Discovery of FLC-8 as the First Covalent FLT3 Inhibitor Targeting Cys807 for FLT3 Mutant Acute Myeloid Leukemia.
Enhanced Antiaging Effect of Fermented Ginseng through Biotransformation of Protopanaxadiol (PPD)-Type Ginsenosides to PPD.
KSR2 functions as a metabolic checkpoint for anti-PD-1 resistance by reprogramming glucose metabolism.
Identification of Autophagy-related Genes of the Osteoarthritis Using Machine Learning Algorithm.
Effect of Bacterial-Enzymatic Synergistic Liquid Fermented Rapeseed Meal on Growth Performance, Intestinal Health, and Muscle Development of Growing Pigs.
Cardiomyocytes FGFBP1 induction by STAT3 drives pathological cardiac remodeling.
Hepatocyte-Targeted Cyclic Peptide LYTACs for PCSK9 Degradation and LDL Cholesterol Metabolic Regulation.
Multi-Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean-Type and Chinese Indigenous Pigs.
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Liquiritin Enhances Chemosensitivity to Doxorubicin in Breast Cancer by Promoting Ubiquitination-Mediated Degradation of MCL1.
KLOTHO Deficiency Drives Ovarian Aging by Inducing Granulosa Cell Senescence and Dysfunction.
Optineurin modulates mTORC2/AKT/STAT3 signaling to control MHC class II expression and adaptive immunity against HSV-1.
Piezo2 Mediates a Vicious Cycle of "Mechanical Homeostasis Imbalance-Inflammation" in Sensory Nerves and the Cartilage Endplate.
Dual-Shell Chitosan/Ferritin Nanocages Enhance the Stability, Intestinal Transport, and Antiviral Activity of EGCG against HBV.
Pyrazolylpyrimidinamines Decorated via Petasis Reaction as Small-Molecule Activators of the RNA-Degrading Ribonuclease IRE1α.
Persistent testicular glycogenolysis and active lipid metabolism during torpor in hibernating Siberian chipmunks.
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
Dual RAF inhibition outperforms RAF-MEK combinations for suppressing ERK signaling in KRAS mutant cells.
Inhibition of iron overload and ferroptosis attenuates sepsis-induced myocardial injury in mice through STAT3/Lcn2 pathway.
Generation of G9 genotype porcine rotavirus using reverse genetics system and its application for antiviral screen and vaccine development.
ANP32E drives lung adenocarcinoma progression via GSK3β-mediated glycolytic reprogramming.
Hantavirus L protein exhibits shutoff activity mediated by its N-terminal endonuclease domain.
Resveratrol improves follicular development in PCOS rats by inhibiting the inflammatory response and pyroptosis of granulosa cells†.
High viscosity microenvironment induces chemoresistance of cancer cells through upregulating P-gp.
Honghe Fujie lotion ameliorates pregnancy-associated vulvovaginal candidiasis in mice by inhibiting the activation of NLRP3 inflammasome.
ACT001 alleviates sepsis-induced acute lung injury by downregulating PANoptosis via the JAK2/STAT3 pathway.
Left bundle branch vs biventricular pacing: mechanistic insights from a canine model.
Manipulation therapy alleviates neuropathic pain via the SOCS1 m(6)A epigenetic loop.
H3K27ac-induced IFITM3 promotes progression of TNBC and resistance to anti-PD-1/PD-L1 therapy via the TNF-α/NF-κB/PD-L1 axis.
METTL16 improves cigarette smoking-induced COPD emphysema through inhibiting autophagy by mediating pri-miR-511 m6A modification.
Neuronal TLR4 upregulation activates the cGAS-STING pathway to induce ferroptosis in EAE mice.
Bee sting acupuncture mitigates osteoarthritis in male mice via PPAR-γ activation: integrated network pharmacology, transcriptomics, and experimental validation.
β-alanine alleviates gout by inhibiting NLRP3 inflammasome activation.
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.
Exploring plasticisers-osteoporosis links and mechanisms: a cohort and network toxicology study.
Tissue-specific effects of bacterial PncA overexpression on NAD(+) metabolism and aging in mice: implications for tissue-specific aging interventions.
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
Astaxanthin ameliorates allergic rhinitis via suppression of the HMGB1/TLR4 signaling pathway.
Propofol Alleviates LPS-Induced Acute Lung Injury by Inhibiting Pulmonary Alveolar Epithelium Pyroptosis.
Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects.
Targeting p97/Valosin-Containing Protein Promotes Hepatic Stellate Cell Senescence and Mitigates Liver Fibrosis.
Effects of borneol on apoptosis of hypoxia/reoxygenation H9c2 cells and myocardial ischemia-reperfusion injury rats.
Osteoclast-expanded supercharged NK cells perform superior antitumour effector functions.
GPX4 predicts poor prognosis and regulates tumor proliferation and senescence in colorectal adenocarcinoma.
Developing a prognostic signature and characterizing the tumor microenvironment based on centrosome-related genes in lung adenocarcinoma.
CXCR1 and CXCR2 Antagonism with G31P Attenuates Chemotherapy-Induced Lung Inflammation and Augments the Gefitinib Therapeutic Response in Lung Cancer.
CAMK2B Impacts the Proliferation, Invasion, and Migration of Glioma Cells via the Ras/Raf/MEK/ERK Signaling Pathway.
HNRNPC as a pan-cancer biomarker and therapeutic target involved in tumor progression and immune regulation.
The Punicalagin Compound Mitigates Bronchial Epithelial Cell Senescence Induced by Cigarette Smoke Extract through the PAR2/mTOR Pathway.
Bioengineered Anti-PD-L1 Functionalized Nanoplatform for Targeted Delivery and Tumor Immune Reprogramming Against Colorectal Cancer.
Targeting Reactive Oxygen Species and Inflammation in Sepsis-Induced Liver Injury with Naturally Derived Superoxide Dismutase-Mimicking Carbon Dots.
Targeting Smad3 Phosphorylation Attenuates Anastomotic Intimal Hyperplasia and Perigraft Fibrosis in Decellularized Tissue-Engineered Vascular Grafts.
Hsa_piR_016975 Is a Novel Target of Nanotherapy that Boosts Hepatoma Progression and Sorafenib Resistance by Abating Maspin/GPX4-Mediated Ferroptosis.
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Integrated transcriptome and proteome analysis identifies keratins as key regulators of corneal scarring in a murine model.
MicroRNA-21 plays a role in exacerbating chronic obstructive pulmonary disease by regulating necroptosis and apoptosis in bronchial epithelial cells.
Assessing the Role of Polyamine Metabolites in Blood and the DNA Methylation of Mycobacterium Tuberculosis in Patients with Multidrug-Resistant Tuberculosis.
CD36 knockdown attenuates pressure overload-induced cardiac injury by preventing lipotoxicity and improving myocardial energy metabolism.
Downregulation of lncRNA MNX1-AS1 promotes the ferroptosis and apoptosis of non-small cell lung cancer.
CLCN5 inhibits tumorigenesis and fatty acid accumulation in clear cell renal cell carcinoma by regulating Enoyl CoA hydratase and 3-Hydroxyacyl CoA dehydrogenase.
Statins and Pacing-Induced Atrial Myopathy: Unraveling Their Role in Atrioventricular Block Patients with Permanent Pacemakers.
Roxadustat: A catalyst for diabetic wound healing through re-epithelialization and angiogenesis.
Enhancing CAR-T Cell Metabolic Fitness and Memory Phenotype for Improved Efficacy against Hepatocellular Carcinoma.
Unlocking the Puzzle of Mammalian Transfection: The Role of the RNA-sensing-Mediated Interferon Response in the Cellular Defense Against Foreign DNA Intrusion.
Macrophage-derived S100A9 promotes diabetic cardiomyopathy by disturbing mitochondrial quality control via STAT3 activation.
Cardiovascular Mettl3 Deficiency Causes Congenital Cardiac Defects and Postnatal Lethality in Mice.
PPARG Activation of Fatty Acid Metabolism Drives Resistance to Anti-HER2 Therapies in HER2-Positive Breast Cancer.
BAP1 Represses Sequential Activation of IRAKs and NF-κB Signaling in Pancreatic Cancer.
BRD7 Inhibited Immune Escape in Nasopharyngeal Carcinoma via Inhibiting PD-L1 Expression.
Dysregulation of SRSF3/circSAMD4/CIRBP Axis Promotes Iodinated Contrast-induced Acute Kidney Injury.
Rabdosia rubescens Inhibits CYP7A1 Expression and Induces Autophagy to Reduce Alcohol-Induced Liver Damage in Mice.
Single-Cell RNA-Seq Recognized Key Genes for Metastasis and Macrophage Infiltration in Colorectal Cancer.
Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization.
Hyperthermia Inhibits Growth and Stemness of Esophageal Squamous Cell Carcinoma Cells Through Promoting Degradation of GLI1.
Identifying the Key Mitochondria-Related Genes in COPD by Integrating Machine Learning and Bioinformatics Analyses.
MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression.
Decoding the Tumor Microenvironment of Myoepithelial Cells in Triple-Negative Breast Cancer Through Single-Cell and Transcriptomic Sequencing and Establishing a Prognostic Model Based on Key Myoepithelial Cell Genes.
Systematic Analysis of an Immune-Related Gene Signature for Predicting Prognosis and Immune Characteristics in Primary Lower Grade Glioma.
Impaired Meningeal Lymphatic Drainage Aggravates LPS-Induced Neuroinflammation and Depression-Like Behaviors in Mice.
Mdivi-1 Attenuates Sepsis-Associated Acute Lung Injury by Inhibiting M1 Alveolar Macrophage Polarization and Pyroptosis.
The Beneficial Effect of Lycium barbarum Polysaccharides on Insulin Resistance and Hepatic Glucose Production in Diabetes.
Taohong Siwu Decoction Combined With the LncRNA H19/miR-675-5p Axis Repairs Limb Ischemia-Reperfusion Injury Through the Regulation of the Wnt3a/Ca(2+) Signaling Pathway.
Interleukin-4-Mediated NLRP3 Inflammasome Activation in Microglia Contributes to Allergic Rhinitis via Central Sensitization.
1p-Enh-regulated CYP4B1 alleviates NNK-induced heart failure and lung cancer via the STAT3 pathway.
TRIM6 affects the prognosis of acute myeloid leukemia through the PI3K/AKT signaling pathway and is associated with immune infiltration.
Downhill running regulates cardiac immune response through GCN2.
Downregulation of NCOA4 expression indicates poor prognosis and promotes the progression of cholangiocarcinoma.
High SRD5A3 expression is correlated with promotion of proliferation and inhibition of apoptosis in B-cell non-Hodgkin lymphoma and suggests a poor prognosis.
Exosomes from human umbilical cord mesenchymal stem cells promote the growth of human hair dermal papilla cells.
Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression.
Comparative analysis of translatomics and transcriptomics in the longissimus dorsi muscle of Luchuan and Duroc pigs.
Weifuchun alleviates MNNG-induced chronic atrophic gastritis by improving the gastric and intestinal microbiota homeostasis.
Electroacupuncture alleviates pain-like behaviors through modulating DNMT3a/MOR signaling pathway in CCI rats.
GsMTx-4 combined with exercise improves skeletal muscle structure and motor function in rats with spinal cord injury.
LARP3 inhibits the apoptosis of hepatocellular carcinoma via the ROS/PI3K/c-Fos axis.
Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways.
PSME2 exacerbates ulcerative colitis by disrupting intestinal barrier function and promoting autophagy-dependent inflammation.
BAP1 complexes with YY1 and RBBP7 and its downstream targets in ccRCC cells.
CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis.
Tetrahydropalmatine improves mitochondrial function in vascular smooth muscle cells of atherosclerosis in vitro by inhibiting Ras homolog gene family A/Rho-associated protein kinase-1 signaling pathway.
Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease.
GFPT2 promotes paclitaxel resistance in epithelial ovarian cancer cells via activating NF-κB signaling pathway.
Lymph Node Exosomes Delivery Attenuates Myocardial Ischemia-Reperfusion Injury via Regulating PTEN-PI3K/Akt Pathway Mediated Myocardiocyte Apoptosis.
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
SYL3C Aptamer-DNA Tetrahedra Conjugates Enable Near-Infrared Fluorescent Imaging of Colorectal Cancer.
Honeysuckle-Derived Exosome-Like Nanovesicles Protect Against Acute Liver Failure by Modulating Gut Microbiota.
Construction of Baicalein-Loaded Chitosan Nanoparticles for Staphylococcus aureus-Induced Lung Infection Remission.
Bone Marrow Mesenchymal Stem Cells-Derived Exosomes Inhibit Apoptosis of Pulmonary Microvascular Endothelial Cells in COPD Mice Through miR-30b/Wnt5a Pathway.
Ti(3)C(2)Tx MXene Potentiates PSAT1-Mediated Osteogenesis Through miR-665/GSK-3β/β-Catenin Axis to Counteract Inflammation-Induced Bone Loss.
Activation of AMP-activated Protein Kinase by Metformin Inhibits Dedifferentiation of Platelet-derived Growth Factor-BB-induced Vascular Smooth Muscle Cells to Improve Arterial Remodeling in Cirrhotic Portal Hypertension.
Ginkgolide B Alleviates LPS-Induced Inhibition of Osteogenic Differentiation in Human Periodontal Ligament Stem Cells by Suppressing the p-IκBα/NF-κB Pathway.
Salidroside Improves Periodontitis by Mitigating Inflammatory Reactions and Enhancing Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Liu Wei Di Huang Decoction Alleviates Renal Fibrosis by Inhibiting Endothelial Mesenchymal Transitions via Upregulating Sirt1 Expression and Inhibiting the Wnt/β-Catenin Signaling Pathway.
Astragaloside IV Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells via Activating PI3K/AKT/eNOS/NO Signaling Pathway: In vitro and in vivo Study.
Lobetyolin Suppressed Osteoclastogenesis and Alleviated Bone Loss in Ovariectomy-Induced Osteoporosis via Hindering p50/p65 Nuclear Translocation and Downstream NFATc1/c-Fos Expression.
Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression.
Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury.
Design, Synthesis and Evaluation of Novel Cyclopropanesulfonamide Derivatives for the Treatment of EGFR(C797S) Mutation in Non-Small Cell Lung Cancer.
Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress.
Skullcapflavone II suppresses TGF-β-induced corneal epithelial mesenchymal transition in vitro.
Qimai Feiluoping Decoction Inhibits EndMT to Alleviate Pulmonary Fibrosis by Reducing PI3K/AKT/mTOR Pathway-Mediated the Restoration of Autophagy.
Hylotelephium mingjinianum Extract Attenuates Oxidative Stress and Inflammation in Experimental Periodontitis.
IGFBP1 is One of 10 Metabolic Factors Predicting Recurrence Free Survival in Gastric Cancer and Promotes Cancer Progression via ZFX-IGFBP1 Axis.
HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages.
MiR-133a-5p Facilitates Cuproptosis in Hepatocellular Carcinoma Through Targeting of ATP7B.
Intermedin(1-53) Improves Atherosclerosis by Reducing Local Endothelial Damage via AMPK Signaling Pathway in Obese apoE-Deficient Mice.
Analysis and Validation of Mitophagy-Related Genes in Diabetic Foot Ulcers.
Elucidating Molecule-Crosstalk of Neutrophil Extracellular Traps Between Cardiovascular Disease and Psoriasis: Insights Into Mendelian Randomization, Single-Cell RNA Analysis, Shared Targets and the Role of Resveratrol.
Uncovering the Interplay of Ferroptosis and Immune System in Coronary Artery Disease: Construction and Validation of a Diagnostic Model.
Identification of Anoikis-Related Genes in Driving Immune-Inflammatory Responses in Ulcerative Colitis Based on Bioinformatics Analysis and Machine Learning.
Fu-Fang-Qi-Di-Hua-Yu-Tang Improves Diabetic Macrovascular Disease via PI3K/AKT Pathway Regulation.
TRIM6 Promotes Cell Cycle and Growth by Modulating p53 Signaling Pathway in Lung Adenocarcinoma.
Integrating Extracellular Vesicles Proteomics and Clinical Parameters to Develop a High-Precision Predictive Model for Severe Asthma.
Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments.
Identifying Chemokine System-Related Phenotype to Predict Immune Feature in Pan-Cancer and Prognostic Signature for Lung Adenocarcinoma.
Volatile Oil From Acorus Gramineus Rhizoma Synergizes with Crebanine to Alleviate Oxidative Stress and Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury by Suppressing GRP78-PERK/ATF6-CHOP and MAPK-NF-κB-TNF-α Signaling Pathways.
Quercetin Inhibits Gastric Cancer Progression via FAM198B/MAPK Pathway Modulation.
Artemether ameliorates type 1 diabetes mellitus by modulating glycolipid metabolism in skeletal muscle.
Mesenchymal stem cells promote erlotinib resistance in non-small cell lung cancer through the HGF-AKT/ERK1/2-OPN pathway.
Study of NOX4/ROS/NF-κB signaling pathway in anti-ischemia-reperfusion injury effect and mechanism of STQJD.
Electroacupuncture alleviates Parkinson's disease by inhibiting the NLRP3 inflammasome pathway.
MiR-124-3p inhibits proliferation, migration, and epithelial-mesenchymal transformation in gastric cancer by targeting ITGB1.
RBM10 suppresses malignant transformation in endometrial cancer via the Hippo-YAP signaling pathway.
Multi-target mechanism of 6-O-Caffeoylarbutin in hyperuricemia treatment through in vivo validation and network pharmacology.
Aerobic exercise and gut flora: a key link to improved cognitive impairment in mice with Parkinson's disease.
Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy.
Experimental validation and identification of ferroptosis-associated biomarkers for diagnostic and therapeutic targeting in hearing loss.
EIF4A3 Promotes Cell Proliferation via CDC5L Upregulation in Human Breast Cancer Cells.
LncRNA C2orf27A Promotes Gastric Cancer by Sponging MiR-610 and Elevating NOX4 Expression.
Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways.
ADAMTS7 Enhances Gastric Cancer Growth and Metastasis by Triggering the NF-κB Signaling Pathway.
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
Study on the mechanism of gracillin inhibiting the proliferation of lung cancer NCI-H1299 cells based on MAPK signaling pathway.
Identification of IGF2BP3 and CENPA as key regulators of immunophenotypes in renal clear cell carcinoma.
Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality.
Setmelanotide-mediated MC4R activation improves hypothalamic obesity via CaMKK2/AMPK pathways.
Synergistic therapy for diabetic retinopathy via dual blockade of VEGF-A and TNF-α with a bispecific nanobody.
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
WNT16 from decidual stromal cells orchestrates M2 macrophage polarization via β-catenin signaling and chromatin remodeling at the maternal-fetal interface.
Cuproptosis-driven reprogramming of fibroblast communication by GK is associated with the immune microenvironment in diabetic foot ulcers.
HOXA5-mediated spatial remodeling of tumor-immune interfaces across cancers promotes AML pathogenesis.
The hypothalamic effects of PACAP on the hypothalamic-pituitary-gonadal axis in male mice.
Thymoquinone and aerobic exercise mitigate HFpEF-induced cardiac injury via Apaf1/Cycs axis regulation.
Cholestane-3β,5α,6β-triol induces cancer cell death by activating GSDME-mediated pyroptosis.
Exploring the mechanism of Heidihuang Pill in the treatment of osteoporosis based on network pharmacology, molecular docking, and experimental validation.
Berberine protects against gefitinib-induced liver injury by inhibiting the HMGB1/TLR4/NF-κB pathway.
Elucidating AML ribosome biogenesis reshaping prognostic assessment and immune microenvironment integrated single-cell and bulk RNA analysis.
Passive hydrotherapy preserves cartilage and muscle integrity in a murine osteoarthritis model: potential role of integrin αV/TGF-β mechanotransduction.
Fangchinoline attenuates hepatic fibrosis by regulating taurine metabolism and oxidative stress.
IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis.
Large extracellular vesicles derived from LPS-preconditioned cardiomyocytes alleviate myocarditis via mediating macrophage polarization and modulating p38 MAPK pathway.
Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.
tRNA-derived small RNA 3' tRF-Ala CGC obstructs NK cytotoxicity via cleavage of membrane protein MICA in colorectal cancer.
Identification of ferroptosis-genes associated with pediatric inflammatory bowel disease bioinformatics and machine learning approaches.
Quercetin inhibits the cAMP/PKA/CREB/glycolysis axis to exert anti-acute lymphoblastic leukemia effects.
Histone-related gene WDR77 promotes tumor progression through cell cycle regulation in skin cutaneous melanoma.
Mechanisms of skeletal muscle atrophy in type 2 diabetes mellitus.
Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway.
Identification and validation of CKAP2 as a novel biomarker in the development and progression of rheumatoid arthritis.
The pivotal regulatory role of the FEV-SLC7A11 axis in ferroptosis elucidates the anti-aging mechanism of β-sitosterol in a cross-species study.
Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout.
Targeting revascularization via tryptophan-indole-NETs axis: the synergistic power of acupuncture and rt-PA thrombolysis in ischemic stroke.
Comprehensive analysis of the functional and immunological significance of ETV4 in pan-cancer and its validation in digestive tumors.
Baicalin enhances respiratory mucosal immunity by modulating antiviral protein expression and T-cell homeostasis during H9N2 infection.
Collectin-11 promotes fibroblast proliferation and modulates their activation status and extracellular matrix synthesis.
Shengyu decoction ameliorates knee osteoarthritis by inhibiting endoplasmic reticulum stress via Piezo1 channels.
CPLX1 is a novel prognostic biomarker in CRC correlating with immunotherapy resistance and ferroptosis.
Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways.
Correlation study of BDNF/TrkB/CREB, violence, and cognitive function in first-episode drug-naive schizophrenia patients.
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Gen-miR-5 derived from Gentianella acuta inhibits PFKP to prevent fibroblast activation and alleviate myocardial fibrosis.
Targeting the BAG2/CHIP axis promotes gastric cancer apoptosis by blocking apoptosome assembly.
METTL3-mediated m6A modification regulates D-galactose-induced skin fibroblast senescence through miR-208a-5p.
Thrombospondin-1 mitigates osteoarthritis progression by inhibiting mechanical stress-induced chondrocyte ferroptosis via the integrin/YAP pathway.
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
(18)F-DOPA uptake illustration acts as an indicator for renal sympathetic activity.
Osteopontin regulates right ventricular failure through integrin ανβ3/PERK/CHOP-dependent inflammatory and apoptotic pathways.
Thymoquinone alleviates the accumulation of ROS and pyroptosis and promotes perforator skin flap survival through SIRT1/NF-κB pathway.
The protective role of cannabidiol in stress-induced liver injury: modulating oxidative stress and mitochondrial damage.
CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.
Ultrasound-assisted H(2)O(2) degradation enhances the bioactivity of Schizophyllan for wound healing and tissue regeneration.
Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE(-/-) mice through the miR-34a/FGF-21 axis.
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
TMED9: a potential therapeutic target and prognostic marker in glioma and its implications across pan-cancer contexts.
High-dose radiation induces dendritic cells maturation by promoting immunogenic cell death in nasopharyngeal carcinoma.
Synthesis, target analysis, and cerebroprotective effects of novel imide antioxidants via the Nrf2/HO-1 pathway in cerebral ischemia-reperfusion injury.
MFAP4 is a novel prognostic biomarker in glioma correlating with immunotherapy resistance and ferroptosis.
Cardiac protection of wogonin in mice with pulmonary fibrosis by regulating Sirt1/ γ-H2AX pathway.
TGFB1/CXCL5 axis regulation by LCN2 overexpression: a promising strategy to inhibit colorectal cancer metastasis and enhance prognosis.
RNF5 inhibits HBV replication by mediating caspase-3-dependent degradation of core protein.
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
Dehydrodiisoeugenol targets the PLK1-p53 axis to inhibit breast cancer cell cycle.
Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency.
CD8+ T cell activation in endometrial cancer: prognostic implications and potential for personalized therapy.
Comprehensive analysis of lncRNAs and mRNAs revealed potential participants in the process of avian reovirus infection.
Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway.
Deciphering the role of CNIH4 in pan-cancer landscapes and its significance in breast cancer progression.
Aberrant expression of PYGB as a potential therapeutic target and its associations with immune cell infiltration in lung cancer.
Isolation, phylogenetics, and characterization of a new PDCoV strain that affects cellular gene expression in human cells.
Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing.
Triptolide alleviates psoriasis through inhibiting the Wnt5a/β-Catenin signaling pathway.
Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway.
Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.
Development of a prognostic model for hepatocellular carcinoma based on microvascular invasion characteristic genes by spatial transcriptomics sequencing.
Harmine derivative B-9-3 inhibits non-small cell lung cancer via the VEGFA/PI3K/AKT pathway.
Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats.
Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis.
Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.
Discovery of novel and highly potent small molecule inhibitors targeting FLT3-ITD for the treatment of acute myeloid leukemia using structure-based virtual screening and biological evaluation.
Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.
Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia.
Alpha-estradiol and (R)-(-)-ibuprofen inhibit gastric cancer progression via GLI1 G-quadruplex.
Genipin attenuates oxidative damage in periodontal tissues by alleviating mitochondrial dysfunction and abnormal glucose uptake through inhibition of UCP2.
FAM49B suppresses ovarian cancer cell growth through regulating MAPK signaling.
RNF200 enhances radiotherapy sensitivity by modulating PD-L1 stability in tumor-associated macrophages of lung cancer.
Splicing factor 3b subunit 4 (SF3b4) is mediated by EP300 and CREBBP to promote colorectal cancer (CRC) proliferation by enhancing autophagy.
ESRP1 drives subtype-specific breast cancer progression through ER-regulated transcriptional programs and EMT-related splicing switch.
Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer.
Engineered RAP-anchored copper-escorting liposomes for FDX1-targeted cuproptosis in glioblastoma therapy.
Bioinspired nano-micron hydrogel microspheres for periodontitis therapy through synergistic multi-targeted remodeling of microenvironment.
Deciphering single-cell landscape unravels cell-type-specific functional roles of RNA m(6)A modification in atherosclerosis.
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway.
Asaraldehyde suppresses non-small cell lung cancer progression via ferroptosis induction and inhibition of PI3K-AKT signaling.
The ubiquitin ligase RCBTB2 regulates aggrephagy and inhibits prostate cancer progression by targeting GPAA1 for degradation.
Identification of sinensetin as a selective inhibitor for mitogen-activated protein kinase kinase 6 and an anticancer agent for non-small cell lung cancer.
Clinical value and molecular role of PRDXs family in prostate cancer.
Mechanistic insights into GPAA1-mediated cold tumor phenotype and immune evasion in colorectal cancer: integrative multi-omics analysis and experimental validation.
Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role.
Metabolic reprogramming-driven stratification and therapeutic targeting in lung adenocarcinoma: implications for prognosis and personalized treatment.
PPP2CA knockdown upregulates the expression levels of ferroptosis-related genes TFRC and ACSL4 in colorectal cancer cells by promoting mTOR phosphorylation.
Ivermectin attenuates Schistosoma japonicum-induced liver fibrosis and is associated with downregulation of YAP signaling.
Ginsenoside Rh2 repressed the progression of prostate cancer through the mitochondrial damage induced by mitophagy and ferroptosis.
CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway.
Saxifraga stolonifera inhibits porcine epidemic diarrhea virus infection by disrupting nucleocapsid protein-p53 interaction.
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
SIRT7 deletion inhibits Glaesserella parasuis-mediated inflammatory responses in porcine alveolar macrophages.
p53 enhances elesclomol-Cu-induced cuproptosis in hepatocellular carcinoma via FDXR-mediated FDX1 upregulation.
Unraveling the role of coagulation-related genes in esophageal squamous cell carcinoma: development of a prognostic model and exploration of potential clinical significance.
TFRC promotes the proliferation, migration, and invasion of osteosarcoma cells by increasing the intracellular iron content and RRM2 expression.
Synergistic effects of 5-fluorouracil in combination with salinomycin promoted ferroptosis via inhibiting SLC7A11/GPX4 in colorectal cancer.
Correlation of heat shock protein 1 expression with progression and prognosis of non-small cell lung cancer.
Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.
Endosialin promotes vascular maturation by inhibiting Cyr61 expression in melanoma metastasis.
Fracture-Induced Immunological Cascades Trigger Rapid Systemic Bone Loss via Osteocyte-Regulated Osteoclastogenesis.
Lysyl Oxidase-Like 1 (LOXL1) Up-Regulation in Chondrocytes Promotes M1 Macrophage Activation in Osteoarthritis via NF-κB and STAT3 Signaling.
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
2'-Hydroxyflavanone inhibits bladder cancer cell proliferation and angiogenesis via regulating miR-99a-5p/mTOR signaling.
IGF1R promotes radiation-induced HSCs activation by regulating DNA-PKcs-mediated DNA damage repair.
Spatial transcriptomics reveals Inhba/Smad2/E2f4 axis in Lrp2(high) thecal cell proliferation in androgen-induced PCOS mice.
Induced neural stem cells ameliorate blood-brain barrier injury by modulating the calcium signaling pathway of astrocyte in cerebral ischemia-reperfusion rats.
HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.
Identification and verification of international neuroblastoma staging system (INSS) stage-related genes as potential biomarkers for neuroblastoma prognostic models.
Aligned nanofibers in biomimetic periosteal extracellular matrix/poly(ε-caprolactone) membranes enhance bone regeneration via the ITGB1/PI3K/AKT pathway.
Prognostic Signature of NETs-Related Genes in Hepatocellular Carcinoma Based on Bulk and Single-Cell Transcriptomics.
Low Indoleamine 2,3-Dioxygenase 1 Expression Enhances Dendritic Cells Response to Tumor Cells Against Hepatocellular Carcinoma.
Garlic oil-loaded nanodisks for the amelioration of acute lung injury via modulation of the NF-κB and Keap1-Nrf2 axis.
Oral supplementation with Lactobacillus fermentum MC018 improves intestinal health, immune response, and growth performance of Zi geese infected with Escherichia coli XH197291.
Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.
Single-Cell RNA Sequencing Integrated with Bulk-RNA Sequencing Analysis Reveals Prognostic Signatures Based on PANoptosis in Hepatocellular Carcinoma.
Echinocystic acid in Momordica charantia L. exosome-like nanovesicles attenuates dengue virus-induced vascular leakage associated inflammatory mediators through macrophage metabolic reprogramming and HIF-1α/p300-CBP interaction.
A mitochondrial ferroptosis-related gene signature predicts prognosis and immune landscape in colon cancer.
Bone marrow mesenchymal stem cell-derived exosomal microRNA-335 alleviates vascular calcification by targeting SP1.
N6-methyladenosine RNA landscape in the aged mouse hearts.
Luteolin attenuates LPS-induced damage in IPEC-J2 cells by enhancing mitophagy via AMPK signaling pathway activation.
Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways.
Chloride channel-3 regulates sodium-iodide symporter expression and localization in the thyroids of mice on a high-iodide diet.
Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation.
MgSO(4) alleviates hippocampal neuroinflammation and BBB damage to resist CMS-induced depression.
Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.
NanoBiT-based Analysis of Canine SOD1 Protein Dynamics: Understanding the Role of CCS and Ebselen Derivatives as Potential Therapeutics for Canine Degenerative Myelopathy.
GSK3A promotes human adenovirus replication and phosphorylates viral L4-22K protein.
Anti-asthmatic effects of andrographolide on OVA-stimulated mice via Th17 cell differentiation-mediated glycolytic pathway.
miR-142 regulates the function of microvascular endothelial cells through MAT2B.
Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NETformation.
Ozone water enema activates SIRT1-Nrf2/HO-1 pathway to ameliorate gut dysbiosis in mice receiving COVID-19 patient-derived faecal microbiota.
Protease Inhibitor VR23 Alleviates Severe Acute Pancreatitis with High Trypsin Synthesis in Mice.
Berberine dissociates mitochondrial complex I by SIRT3-dependent deacetylation of NDUFS1 to improve hepatocellular glucose and lipid metabolism.
HBV Precore G1896A Mutation Promotes Malignancy of Hepatocellular Carcinoma by Activating Endoplasmic Reticulum Stress to Enhance Aerobic Glycolysis.
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways.
Daughter Cells Budding From PGCCs and Their Clinicopathological Significances in Oral Squamous Cell Carcinoma.
EIF3B‑METTL3 complex promotes cell proliferation, invasion and EGFR/AKT signaling in cervical cancer.
Oxidative stress activates YAP/TEAD1/NCOA4 axis to promote ferroptosis of endplate chondrocytes and aggravate intervertebral disc degeneration.
Overexpression of JAML in colorectal cancer cells predicts higher radiosensitivity by inactivating ATR pathway.
Changes of N6-methyladenosine and ferroptosis in cadmium-induced reproductive toxicity of male mice fed a high fat and high sugar diet.
Telaprevir attenuates caspase-11-dependent pyroptosis in mouse heart following ischemia/reperfusion via inhibition of MALT1/TRAF6 pathway.
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels.
Study of the Reciprocal Interaction Between Tumor Cells and Macrophages Based on the Biomimic Microfluidic Device.
ZMYND8 promotes the Warburg effect and tumorigenesis through c-Myc activation in pancreatic cancer.
RBM5 recruiting MGC32805 in a sandwich mode and inducing ΔFAS neoantigen and triggering FAS properties switch: implication in colorectal cancer.
Vimentin intermediate filaments orchestrate DNA nonhomologous end joining repair and lipolysis after DNA damage.
Up-regulation of NGEF via the BRAF(V600E) /ERK/AP1 pathway enhances invasion and migration abilities of BRAF(V600E)-mutant thyroid cancer.
p62/SQSTM1 impairs immunotherapy in lung adenocarcinoma by suppressing immune infiltration and peripheral immune response.
Mechanistic Insights Into hsa_circ_0005654-Induced Ferroptosis in Diabetic Foot Ulcers Through IGF2BP2 Interaction.
SH3GL1 mediates B7-H3 recycling and enhances the immune escape in non-small cell lung cancer.
Insights Into the Mechanism of Action for Qingzhi Decoction for the Treatment of Non-Alcoholic Fatty Liver Disease via Regulation of the IRS/PI3K/Akt Signaling Pathway and the NRLP3 Inflammasome.
A Small Molecular Weight Saccharide Fraction From Panax quinquefolium L. Inhibited Non-Small Cell Lung Cancer via Endoplasmic Reticulum-Stress Mediated Apoptosis.
Study on the Effect and Mechanism of Weichang'an Pill and Its Extract on Slow Transit Constipation.
Glycosylated protein-related microenvironmental features in breast cancer are associated with patient prognosis.
Cytotoxic effect of bladder cancer oncolytic virus on bladder cancer stem-like cells via pyroptosis pathway.
Integrating single-cell transcriptomics, molecular docking, and dynamics simulations to characterize protein kinase X-linked mechanisms in osteosarcoma.
Upregulation of has_circ_0008389 promotes esophageal squamous cell carcinoma progression via miR-761 sponging and P2RY2 mRNA stabilization.
Integrative spatial multi-omics identifies the TEK receptor tyrosine kinase as a central biomacromolecule of endothelial-immune interactions in glioblastoma.
C-Arg9-APCR3-VHL promotes β-catenin degradation via the VHL-mediated ubiquitin-proteasome system in APC-mutant colorectal cancer.
IAV inhibits the host antiviral defense mediated by LncRNA-LRIR to enhance viral replication.
A novel glucomannan from Bletilla striata ameliorates colitis: Restores intestinal barrier, alleviates inflammation, and modulates the gut flora.
Rational design of a cost-effective IRES-stem-loop translation system independent of cap and poly(A) tail.
DDX3X/MAVS alleviates doxorubicin‑induced cardiotoxicity by regulating stress granules.
Direct effects of the small molecule PD‑L1 inhibitor BMS‑202 on A375 melanoma cells: Anti‑tumor activity accompanied by increased mitochondrial function.
WTAP-mediated m(6)A methylation of circRNA_404908 promotes esophageal squamous cell carcinoma progression.
Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7.
A novel glutamine metabolism-related risk model for prognostic prediction of liver hepatocellular carcinoma.
TRIM29 promotes glioblastoma progression via ubiquitinating NEFL and activating the PI3K/AKT signaling pathway.
GABA ameliorates diet-induced hepatic steatosis and insulin resistance by inhibiting macrophage activation.
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription.
Testosterone-mediated regulation of renal GSTA1/2 expression in male mice.
TLR4 signal inhibition alleviates alkali-burn induced corneal neovascularization.
PINK1-mediated mitochondrial autophagy protects lens epithelial cells by reducing ROS and apoptosis.
Empagliflozin Promotes Revascularization in Diabetic Mice Hindlimb Ischemia by Improving Vascular Endothelial Cell Function.
Benserazide‑mediated targeting hexokinase 2 enhances the cytotoxicity of cisplatin in non-small cell lung cancer cell models.
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Alexidine dihydrochloride enhances the sensitivity of human hepatocellular carcinoma to disulfidptosis via ATF4-DDIT3 activation.
Nebulized MSC exosomes promote the transdifferentiation of transitional state cells against acute lung injury through STAT3/Krt8/AQP5 axis.
Endoplasmic reticulum-anchored nonstructural proteins drive human astrovirus replication organelle formation.
IAV NS1 carried by exosomes promotes IL-10 production by the PI3K-AKT-GSK3β-CREB pathway.
Comparative neurotoxic effects and mechanism of cadmium chloride and cadmium sulfate in neuronal cells.
Impact of NLRP6 inflammasome on neuroinflammation in temporal lobe epilepsy.
Overexpression of PBX1 attenuates oxidative stress and apoptosis in diabetic cardiomyopathy by transcriptionally inhibiting TXNIP.
MSC-EVs alleviate sepsis-induced acute lung injury through inhibiting NET-triggered damage to adherens junctions of endothelial cells.
Evaluation of ethanolic extract of Clinacanthus nutans leaves in C2C12 myotubes: anti-exercise fatigue activity.
PPARγ is a potential therapeutic target for radiation enteritis via suppressing ferroptosis, mediated by the GAPDH/glycosylation axis.
Association of elevated ACSL4 expression with impaired endometrial receptivity in endometriosis and restoration by ACSL4 inhibitor PRGL493.
Reduced level of BMI1 inhibits trophoblast proliferation and migration via the epigenetic enhancement of CSTA and TGFB2 in spontaneous abortion.
Zebrafish CD44a variants suppress antiviral immunity through regulation of RIG-I ubiquitination and degradation.
SUMO E1 covalent allosteric inhibitors upregulate polyamine synthesis via the MAT2A-AdoMetDC axis.
Optimized synthesis of 5N-D and the exploration of its role as a promising anti-aging agent via AKR1B1 inhibition and PI3K/Akt/Nrf2 regulation.
Development of Adamantane-based hydrophobic tags targeting anaplastic lymphoma kinase with enhanced antitumor activities.
Design, synthesis, and biological evaluation of Pseudolaric acid B derivatives as Ferroptosis inducers in Colon Cancer cells.
Energy metabolism disturbance induced by atorvastatin exposure on yellowstripe goby (Mugilogobius chulae) larvae based on transcriptome and metabolome analysis.
Carbon black induced pulmonary fibrosis through piR-713551/PIWIL4 targeting THBS2 signal pathway.
Irisin/FNDC5 Regulates Endothelial Function to Improve Post-Stroke-Induced Cognitive Dysfunction by Stimulating AMPK-eNOS Signaling.
Celastrol protected the MPTP-injected mice Parkinson's disease model via redox regulation of CDC37.
Danggui buxue decoction attenuates doxorubicin-induced cardiotoxicity by inhibiting ZBP1-mediated PANoptosis in vivo and in vitro.
Salidroside alleviates bone cancer pain by inhibiting Th17/Treg imbalance through the AMPK/SIRT1 pathway.
Multi-omics analysis of the active components and mechanisms of Baojin Chenfei formula in silica-induced murine silicosis.
Ginger-processed Magnoliae Officinalis Cortex ameliorates ovalbumin-induced asthma by alleviating inflammation via the gut-lung axis.
Tanshinone IIA attenuates sepsis-induced lung injury by reducing VEGFR2/PI3K/AKT-driven mitochondrial disruption dependent apoptosis.
Proteomics analysis and immune profiling reveal regulators of PD-L1 in oesophageal squamous cell carcinoma.
Donkey Milk Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis by Protecting Gut Barrier Function, Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway, and Modulating Gut Microbiota.
Protective Effects of Ganoderma Triterpenoids Supplementation Against Myocardial Injury in Exhaustion Exercise Mice via Regulation of the Keap1/Nrf2/HO-1 Pathway.
Inhibition of Iron Death by Lycium barbarum Polysaccharides Ameliorates Myocardial Injury in Sepsis: A Pharmacological Mechanism Study Based on the NRF2/HO-1 Pathway.
Dual-mode immunotherapy: ultrasound responsive zinc-based nano-contract agents synergistically activate the GAS-STING pathway for enhanced tumor sono-metalloimmunotherapy.
SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1-Mediated Transactivation of CD47.
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer.
Vimentin intermediate filaments facilitate transportation of hepatitis C virus components.
Sfrp2-deficient colonic fibroblasts drive mucosal inflammation and epithelial injury in ulcerative colitis.
Enhancing the antitumor activity of CD19/BCMA CAR-T cells in vitro with a PD1IL7R chimeric switch receptor.
Cryptococcus neoformans and the EGFR Puzzle: Uncovering a Novel mechanism for blood-brain barrier crossing.
5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair.
TMAO regulates OTUB1-mediated SLC7A11 stability to promote NAFLD progression.
Lidocaine intervention attenuated postoperative delirium by reshaping intestinal flora and modulating microglia M2 type polarization and blood-brain barrier.
Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity.
A Preliminary Study of the Relationship Between Zinc and the AhR Signaling Pathway During Palatal Development.
A Novel Nuclear-Localized Micropeptide, MP60, Promotes Hepatocellular Carcinoma Progression via the Epithelial-Mesenchymal Transition.
Study on the role of FN1 in chronic obstructive pulmonary disease.
Epigenetic reprogramming of HDAC2 in CA1 excitatory neurons determines Pb-induced non-spatial memory deficits.
Design, synthesis and biological evaluation of triazolothiadiazole derivatives as FSP1 inhibitors for sensitizing cancer cells to ferroptosis.
Hydroxysafflor yellow A alleviates ischemic myocardial injury by targeting SF3A1 to improve mitochondrial energy metabolism.
KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1.
Artemisinin alleviates Parkinson's disease by targeting Adcy5-Gch1 axis to trigger a cascade generation of BH4 and dopamine in rats.
ROS and Drp1-mediated mitochondrial fission contributes to the hyposalivation caused by Sjögren's disease.
Peripheral blood mesenchymal stem cells repair oxidative damage and apoptosis in an H(2)O(2)-induced vitiligo oxidative stress in vitro model via the IL-10-mediated PI3K/AKT pathway.
Circular RNA hsa_circ_0006522 correlates with unfavorable prognosis and promotes the proliferative, migrative, and invasive abilities of breast cancer cells.
Constructing a chemokine-based model and identifying CCL17 as a core biomarker associated with immune infiltrates in thyroid cancer.
N6-adenosine methyltransferase METTL4 is a potential prognostic biomarker and associates with cell cycle regulation and immune infiltration in glioma.
Lactobacillus johnsonii-derived extracellular vesicles restore mucosal immunity via taurine-linked Th17/Treg and IgA/IgG regulation in colitis.
ATG7-induced autophagy inhibits ferroptosis and promotes the progression of colorectal adenocarcinoma.
Novel Pathogenic Biallelic Variants in KIAA0586 Expand the Variant Spectrum of Ciliopathies.
Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway.
Research on the inhibitory effect of hydrogen gas on ovarian cancer and potential mechanisms.
Differential regulation of mesoscale chromosome conformations in osteoblasts and osteosarcoma.
Identification of a dihydroartemisinin-related prognostic signature and its contribution to cancer associated fibroblast of the tumor microenvironment of pancreatic cancer.
PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis.
Comparison of Quercetin and Isoquercitrin's Anti-Heart Failure Activity via MAPK Inflammatory Pathway and Caspase Apoptosis Pathway.
Harnessing indole scaffolds to identify small-molecule IRE1α inhibitors modulating XBP1 mRNA splicing.
Mechanisms of Saposhnikovia divaricata in attenuating NaAsO(2)-induced neural injury via the PI3K/AKT pathway.
Unveiling the genetic biomarkers for ageing: evidence from a large sample genome-wide association study and in vivo validation.
The synergistic administration of sanguinarine and curcumin ameliorates indomethacin-induced small intestinal injury in rats through the modulation of Nrf2 and NF-κB signaling pathways.
Rutaecarpine alleviates liver fibrosis by modulating the TRPV1/Connexin 43 axis: A study based on transcriptome data, single-cell sequencing data, and cell experiments.
ComplexDnet: A Network-Based Strategy to Discover Critical Targets and Screen Active Compounds for Complex Diseases.
Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis-infected bovine mammary epithelial cells identifies proteins and miRNAs that induce inflammatory responses in macrophages.
Dynamic U2AF cycling defines two phases of cotranscriptional pre-mRNA splicing.
Systematic reevaluation on the antipyretic, analgesic effects, and uncover the mechanisms of Chaiqin Qingning capsule, a traditional Chinese medicine, via establishing lipopolysaccharide - induced fever models, physical and chemical - stimuli pain models.
Fufang epimedium formula alleviates acute liver injury through dual modulation of PI3K/AKT/Bcl-2 anti-apoptotic signaling pathway and cGAS-STING-IRF3 anti-inflammatory signaling pathway.
Aurantii Fructus alleviates depression via modulating hippocampal caspase-4-linked neurogenesis and synaptic plasticity in mice.
Atractylenolide III attenuates acute kidney injury through phosphorylation of PIK3CA: Functional activation and molecular interaction analysis.
The therapeutic mechanisms of Compound Kushen Injection in relieving cancer-induced bone pain by targeting Nav1.7 and microglial activation.
Tianlong kechuanling ameliorated COPD-PH through DNMT3A-GSDMD axis-dependent regulation of endothelial cell pyroptosis.
Shenling Baizhu Powder and Betulin attenuate sepsis-induced intestinal injury by targeting GADD45B/TAOK1/p38 MAPK pathway.
In-depth investigation of the mechanism in rats with alcoholic acute pancreatitis via DNA methylation, intestinal flora, and fecal metabolomics.
NCAPH-YAP1 interaction promotes breast cancer stemness and tumor progression.
METTL3-Driven m6A Epigenetic Remodeling of lncRNA-AU020206 Stabilizes SLC7A11 via YTHDC2 Attenuates Apoptosis and Ferroptosis in Cerebral Ischemia/Reperfusion Injury.
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
ARRDC1 inhibits the replication of Semliki Forest virus by regulating the ubiquitination and degradation of viral nsP4.
taVNS alleviates preeclampsia-induced vascular endothelial dysfunction via α7nAChR- IP3R1/GRP75/VDAC1 signal pathway.
YTHDF1-mediated mitochondrial dysfunction and allergic airway inflammation by interaction with β-catenin/TCF4 signaling.
Fluzoparib disrupts Golgi apparatus to inhibit O-GlcNAcylation and nuclear translocation of β-catenin to attenuate ovarian cancer invasion and metastasis.
Colla Corii Asini regulate collagen regeneration in UV exposure-induced skin photoaging in mice.
Sheng Mai San Mitigates Heat Stress-Induced Myocardial Injury by Coordinated Regulation of the Keap1-Nrf2-HO-1 and Stub1-HSF1 Signaling Pathways.
Lumpy Skin Disease Virus ORF137 Protein Inhibits Type I Interferon Production by Interacting with and Decreasing the Phosphorylation of IRF3.
Cytoplasmic localization of PUS7 facilitates a pseudouridine-dependent enhancement of cellular stress tolerance.
Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson's Disease Model: Transcriptomic Evidence.
ZNF180 modulates tumor intrinsic immunotherapy resistance in melanoma through driving plasticity.
Chronic Exposure to Sunset Yellow Promotes Susceptibility to Experimental Colitis in Mice through Gut Microbiota.
Metallothionein 2A-Silencing Antimonene-Based Nanoagonist for Amplifying the Photothermal Immunotherapy of Gynecologic Malignancy.
Multi-Omics Insights into Postnatal Skeletal Muscle Development in Duroc Pigs.
S-nitrosylation of pVHL regulates β(2) adrenergic receptor function.
Angptl4 is upregulated by microenvironmental factors during the wound healing process and promotes epidermal stem cell proliferation via PRL8a6.
Podoplanin-TGF-β1 Autocrine Loop: Pivotal Regulator of Islet Stellate Cell Activation via Cell Deformation, Orchestrating Islet Fibrosis in Diabetes.
African swine fever virus pNP419L inhibits type I interferon signaling by blocking ISGF3-mediated transcriptional activation.
Based on disulfide accumulation, leveraging a THBS1-signature to improve the outcome of head and neck carcinoma patients.
Human umbilical cord mesenchymal stem cell -derived exosomes alleviated the toxic effects induced by lead on HK-2 cells via regulating the unfolded protein response.
Exploring the potential mechanisms of Jinglinzi powder in treating hepatocellular carcinoma based on LC-MS, network pharmacology, molecular docking, and experimental validation.
Methionyl-tRNA synthetase 1 participates in hepatocellular carcinoma and its regulated gene profile possesses potent prognostic ability.
Dietary 1,3-diacylglycerol ameliorates hyperuricemia via dual modulation of urate transporters and inflammasomes in mice.
Hydroxypropyl-β-cyclodextrin inclusion complex improves the percutaneous therapeutic effect of eugenol on psoriasis mice.
Inhibition of GRK2 mitigates renal fibrosis via oxidative stress pathway.
Integrative proteomic characterization of human lung adenocarcinoma with KRAS G12 mutations reveals molecular pathogenesis.
MAO-A inhibition alleviates sepsis-driven lung injury via Nrf2/HO-1 pathway activation and suppression of pyroptosis.
Effects on Oral Squamous Carcinoma Cell Lines and Their Mechanisms of Pyrazole N-Aryl Sulfonate: A Novel Class of Selective Cyclooxygenase-2 Inhibitors.
Oligomeric Proanthocyanidins Reverse Lenvatinib Resistance in Hepatocellular Carcinoma Through ITGA3-Mediated Pathway.
Time-Restricted Feeding Affects Energy Metabolism in Lactating Striped Hamsters (Cricetulus barabensis, Cricetidae, Rodentia).
Mechanistic study on the inhibition of triple-negative breast cancer progression by LncRNA TFAP2A-AS1 through the regulation of miR-6892/PHGDH.
Strontium-Loaded Chitosan/Wood Hydrogel with Anisotropic Cellular Architecture for Enhanced Critical Bone Regeneration.
11β-HSD1 inhibitor alleviates sepsis-induced cardiac dysfunction by regulating macrophage polarization via the AMPK/mTOR autophagy pathway.
Prognostic significance of BATF family genes and correlation with immune infiltration in colorectal cancer.
N-acetyltransferase 10 Promotes Pancreatic Cancer Progression Through ZEB1/MT1-MMP Axis.
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
The role of endoplasmic reticulum stress in BPS-induced disruption of endometrial decidualization.
m(6)A-methylated TAL1 exacerbates lipid accumulation in ethylene bisdithiocarbamate metabolite-induced anorectal malformations in rat fetuses via miR-205/LCOR signaling.
Multi-omics reveals the polyethylene terephthalate carcinogenicity: Cancer progression and immune microenvironment.
Aloperine ameliorates radiation enteritis by driving the TAS2R138-PLCβ/GAPDH axis-mediated glucose metabolic reprogramming to inhibit ferroptosis in intestinal epithelial cells.
Crocin drives intestinal microbiota variation in a rat model of Alzheimer's disease by reducing DKK3 expression.
LAPTM4B as a key regulator in the copper-induced endoplasmic reticulum-lysosome interplay disorder in duck liver and the protective role of baicalin.
Dual inhibitors of butyrylcholinesterase and histone deacetylase 6 for the treatment of Alzheimer's disease: design, synthesis, and biological evaluation.
PADI1 aggravates endoplasmic reticulum stress in trophoblast cells by inhibiting the FAK-ERK signaling pathway.
Isoquercitrin mitigates intestinal ischemia-reperfusion injury by regulating intestinal flora and inhibiting NLRP3 inflammasome activation.
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
A potential strategy for improving offspring behavior in maternal immune activation: Amantadine-mediated suppression of neuroinflammation.
YTHDF1 regulates the proliferation and differentiation of keratinocytes via the PI3K/AKT signaling pathway in atopic dermatitis.
SUR1-TRPM4 Regulates Aquaporin-4 Subcellular Localization by Astrocytic Endfeet Calcium Signals Following Status Epilepticus.
Liver sinusoidal endothelial cells secret C-X-C motif chemokine ligand 10 to promote the recruitment of invariant NKT cells in acetaminophen-induced liver injury.
Identification and Experimental Verification of PDK4 as a Potential Biomarker for Diagnosis and Treatment in Rheumatoid Arthritis.
Proteomic Analysis Provides a New Sight Into the CRABP1 Expression in the Pathogenesis of Hirschsprung Disease.
UQCRC1 is a Key Pathogenic Determinant and Potential Therapeutic Target for Cognitive Impairment in Alzheimer's Disease.
Dual targeting of the Wnt and DNAJB6/MRJ regulatory loop as an anti-RSV strategy.
Exosome miR-6990-5p from MMP14(high) Macrophage Promotes Fibrosis Through Th17 Cell Differentiation in Hypersensitivity Pneumonia.
TAP1 promotes immune escape by activating JNK/STAT1/PD-L1 signaling in EBV-associated gastric cancer.
Nonstructural Protein 1 Mediates HMGB1 Release by Targeting Histone H1.0 After Respiratory Syncytial Virus Infection In Vivo and In Vitro.
High level expression of OSBPL11 is associated with atherosclerosis and Alzheimer's disease.
OTUD1 downregulates PD-L1 expression by deubiquitinating STAT3 and promotes the immune response in ccRCC.
Targeting miR-144-5p/ACSM1 Axis Alleviates Doxorubicin-Induced Heart Failure by Inhibiting Lipid Peroxidation.
HOMER3 orchestrates SRC-YAP1 activity that promotes tumor cell growth and antagonizes anti-tumor immunotherapy in prostate cancer.
RCN3 functions as a tumor promoter in colorectal cancer by modulating the GRP78-PI3K-AKT signaling pathway.
LGI3 promotes the progression of TFE3-rearranged renal cell carcinoma through GEMIN6/AURKB axis.
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
AXL-mediate GEF-H1 phosphorylation was involved in microglia synapse phagocytosis in 5xFAD mice.
Engineering a Lipid Nanoparticle with Atypical Calcium Crystal Structure for Enhanced IFNβ-Mediated Immunotherapy.
Umbilical cord blood-derived exosomes deliver miR-182-5p to Therapeutically target the MYD88/NF-κB signaling pathway in rat peri-implantitis.
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Engineered biomimetic vesicles induce cuproptosis and disrupt efferocytosis for metastatic adenoid cystic carcinoma immunotherapy.
Analysis of the therapeutic effect and potential mechanism of Fe(3)O(4)-polydopamine nanoparticles in enhancing mesenchymal stem cells therapy for pulmonary fibrosis.
SAMHD1 deficiency disrupts macrophage autophagy-lysosomal homeostasis and promotes inflammation via the mTOR-MITF-CTSD axis in ulcerative colitis.
Mechanism of Banxia Houpo Decoction in Treating Gastroesophageal Reflux Disease: An Integrated Approach of Compound Analysis, Network Pharmacology and Empirical Verification.
The long noncoding RNA SNHG12 defines KEAP1 stability and ferroptosis susceptibility by targeting E3 ligase TRIM25.
TSLP mitigates post-infarction myocardial remodeling by promoting eosinophil recruitment and inhibiting JAK1-STAT5-mediated ferroptosis.
Aspirin-Inspired 6-O-Carboxymethyl-N-Acetylglucosamine: A potent antitumor agent with enhanced efficacy.
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Scorpion venom heat-resistant synthetic peptide regulates Nrf-2 to alleviate neuronal pyroptosis in an AD model induced by endoplasmic reticulum stress under PM(2.5) exposure.
Licoisoflavone A inhibits colorectal cancer cell proliferation through targeting CDK2-Cyclin E1 axis-mediated cell cycle transition.
The exosomal miRNA-3184-3p derived from highly metastatic melanoma cells promotes metastatic competency via the positive feedback loop of NLK/Wnt/S100A11.
Identification and characterization of a potent peptide inhibitor targeting FOXM1 in cancer therapy.
Gut microbiota derived butyrate enhances ferroptosis sensitivity in endometriosis through FFAR2/PPAR-γ/PINK1/Parkin mediated mitophagy.
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Fe(2)O(3) nanoparticles induce ferroptosis by binding to the N-terminus of ACSL4 and suppressing its ubiquitin-mediated degradation.
Enhancing the encapsulation efficiency, bioavailability, and antioxidant efficacy of quercetin and maize peptide by a novel multi-frequency pulsed ultrasonic-assisted nanoliposomal encapsulation system.
TRIM45 restricts influenza virus infection through modulating the chaperone-mediated autophagic degradation of viral PB2 protein.
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation.
M6A-mediated uc003pes.1 stability regulates proliferation and migration of human coronary artery smooth muscle cells via scaffolding STAT1 and USP10.
MitoQ for vitiligo by mitigating PARP1 translocation aberrations: Network pharmacology and experimental validation.
LILRB4 exacerbates myocardial ischemia-reperfusion injury by promoting inflammation and pyroptosis.
Galectin-3 gene deletion alters lipid profile in healthy and cardiomyopathy mouse hearts.
Exploring the mechanism of Levistolide A in the treatment of lung cancer cells based on network analysis, molecular docking and experimental validation.
High-Calorie Diet During Pregnancy Leads to Muscular Fibrosis and Neuromuscular Damage in Offspring Mice.
Targeting the Phosphoinositide 3-Kinase/Protein Kinase B Pathway Suppresses Y-Box Binding Protein 1 Expression and Inhibits Colorectal Cancer Progression.
Ononin, a Natural Isoflavone Glycoside, Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Regulating Neuroinflammation and Oxidative Stress.
Huo Po Xia Ling decoction exerts preventive and improvement effects on gastric precancerous lesions by remodeling gut microbiota and associated metabolites.
Columbianadin targets TRIM7 to maintain P2X7 palmitoylation, inhibiting cuproptosis in synovial M2 macrophages.
Selenium alleviates cadmium-induced Golgi stress via HSPB7/GM130/CX-43 axis in the heart of sheep.
A Novel Injectable Composite Hydrogel HAp-GelMA Co-Doped Magnesium/Zinc Promotes Bone Generation and Angiogenesis Synergistically.
SIRT1 Expression in Human Gastrointestinal Tumors and Its Clinical Significance.
NSUN2-mediated m5C hypermethylation of hsa_circ_0004516 promotes breast cancer brain metastasis by activating AKT signaling.
LncRNA MEG3/CTCF-CXCR4 axis functions in the regulation of breast cancer cell migration.
Silibinin attenuates 3-nitropropionic acid-induced ovarian toxicity by alleviating oxidative stress and granulosa cell apoptosis.
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway.
Tumor suppressor FBXO11 drives ubiquitin proteasomal degradation of KIF2C to limit ovarian cancer progression and is transcriptionally repressed by ZNF217.
Curcumin alleviates lipopolysaccharide-induced alveolar epithelial Glycocalyx damage by modulating the Rac1/NF-κB/HPSE pathway.
IL-6/KIAA1429 promotes ferroptosis resistance in endometrial cancer through m6A modification of DDIT3.
Effects of higenamine on M1/M2 polarization and osteoclast differentiation in rheumatoid arthritis via the THBS-1/TGF-β signaling pathway.
Cordycepin promotes the survival of random-pattern skin flaps via autophagy in a rat model.
KIF18B drives the malignant progression of gliomas by activating the Notch pathway.
EP300-interacting inhibitor of differentiation 3 is required for spermatogenesis in mice.
DEL-1 Protects the Myocardium From Ischemia/Hypoxia Injury Through Regulating the Sirt1/NF-κB Signaling Pathway.
Sonogenetic neuromodulation prevents post-myocardial infarction malignant arrhythmia and cardiac remodeling through the brain-heart circuit.
Targeting IGF1R Overcomes Armored and Cold Tumor Microenvironment and Boosts Immune Checkpoint Blockade in Triple-Negative Breast Cancer.
Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis-Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR-433-3p/HMGA2 Axis.
EOAI3402143 inhibits lung adenocarcinoma progression through the NF-κB/NR4A1 pathway.
P2RX4 promotes hepatocellular carcinoma progression via calcium-mediated PI3K/AKT activation and immune remodeling.
Single-cell RNA sequencing reveals that Danggui Buxue Tang decoction facilitates wound healing after anal fistula by promoting M2 macrophage polarization.
Network Dysfunction Precedes Neurodegeneration in a dox-Regulatable TDP-43 Mouse Model of ALS-FTD.
Nanovesicles Synergistically Regulate Ferroptosis Characteristic Macrophage-Induced Angiogenesis via Ferritin Heavy Chain 1/Glutathione Peroxidase 4 Pathway to Promote Peripheral Nerve Regeneration.
Fosl2 facilitates chromatin accessibility to determine developmental events during follicular maturation.
Ferroptosis-Enhanced Radiopharmaceutical Therapy via a Manganese-Based Nanoplatform.
Plin4 modulates lipid droplet accumulation and ferroptosis in neurons exposed to benzo[a]pyrene.
Development of a potent BET inhibitor for the treatment of renal fibrosis.
LncPRESS1 promotes the progression and cisplatin resistance of breast cancer through upregulation of ENO1 and activation of glycolysis.
Multi-omics and network pharmacology approaches reveal the mechanism of action of KeKe tablet against post-infectious cough.
COL6A1, LAPTM5, and ZFAND2A as Crucial Biomolecules Driving Immunoregulation in Human Nucleus Pulposus Degeneration.
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
Effect of fibrinogen like protein 1 on cisplatin-resistance in laryngeal carcinoma through targeting integrinβ1 in vivo and in vitro.
A novel prognostic tool for triple-negative breast cancer: creating and testing a parthanatos-related gene model.
ANK3 Is Regulated by Recursive Splicing and Inhibits Hepatocellular Carcinoma Metastasis by Inhibiting E-Cadherin Protein Degradation.
Lentinan ameliorates angiotensin II-induced hypertension-associated intestinal barrier injury through inactivation of PSMB8-ATRAP signaling.
LncRNA MIR17HG accelerates the development of atherosclerosis by promoting macrophage pyroptosis through the miR-301a-3p/TXNIP pathway.
1,8-Cineole alleviates spinal cord injury by inhibiting microglial pyroptosis via the P38 MAPK and PI3K/AKT/NLRP3 signaling pathways to protects neurons.
Anemoside B4 improves cardiac function after myocardial infarction by regulating HTR2A/ERK pathway.
Oridonin alleviates SiNPs-induced pulmonary fibrosis by inhibiting pyroptosis via IRE1α-XBP1s-NLRP3 pathway.
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
Neuronal pentraxin 1 accelerates post-stroke atherosclerosis by inducing endothelial cell senescence.
Effects of Nutritional Disturbances on the Structure and Function of Mitochondria, Oxidative Stress Level, and Fat Deposition in Chicken Liver Cells.
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
Dietary quercetin supplementation alleviates claw lesions in dairy cows by modulating the PI3K/Akt and NF-κB signaling pathways.
Med20 regulates myelination in the peripheral nervous system by modulating ferroptosis of Schwann cells.
STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma.
Combination of B-AP15 and HSP90 inhibitor tanespimycin induces ROS-mediated cytotoxicity in human lung cancer cells.
Macrophage-derived exosomes carrying miR-30a-5p alleviates IL-13/IL4-induced epithelial-mesenchymal transition in mouse bronchial epithelial cells via Runx1.
Villin like suppresses nasopharyngeal carcinoma proliferation by downregulating MYC.
Dysregulated autophagy, neural signaling pathways and gut-brain axis in a novel vestibular migraine-like rat model: implications for pathogenesis.
Human induced pluripotent stem cell-derived cardiomyocytes improve recovery from myocardial infarction in non-human primates.
Genotype and phenotype correlation analysis in 27 families with multiple osteochondroma and validation by ATDC5 chondrocyte models.
Mitochondria-associated endoplasmic reticulum membrane (MAM)-associated calpains system in preeclampsia.
Endoplasmic reticulum-resident protein DNAJC10 inhibits glioblastoma metastasis by suppressing XBP-1s-driven EGFR transcription.
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
α-Ketoglutarate Ameliorates Sarcopenia in D-Galactose-Induced Aging Mice by Modulating Protein Homeostasis and Optimizing Mitochondrial Function.
IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders.
Molecules interacting with CasL-Like 2 enhances tumor angiogenesis and progression by activating mTOR/HIF1α/VEGF pathway in kidney renal clear cell carcinoma.
Efficient genetic perturbation of murine sensory neurons in vivo using CRISPR/Cas9.
Paeonol reduces IL-1β induced apoptosis and degeneration by regulating MAPK pathway in nucleus pulposus cells.
Single-cell and bulk transcriptomic analyses reveal ITGA5-driven epithelial-mesenchymal transition and metabolic adaptation in thyroid cancer.
KAZN methylation as a potential diagnostic and prognostic marker in non-small cell lung cancer.
Targeting PURPL RNA enabled rejuvenation of senescence cells via epigenetic reprogramming.
A Cell-Potent Bisubstrate Inhibitor to Probe NatD Acetyltransferase Activity.
The CCL20-integrin α5β1 interaction enhances TGF-β/Smad signaling to promote fibroblast activation in pulmonary fibrosis.
Whole-transcriptome sequencing analysis of spinal neuronal ferroptosis in aggravating neuropathic pain.
Endoplasmic reticulum stress and autophagy as potential therapeutic targets in SERPINF1 mutation-induced type VI osteogenesis imperfecta.
Simultaneously induce apoptosis and inhibiting metastasis of Triple negative breast cancer Enabled by a highly potent NIR fluorescent inhibitor.
Bisphenol S as an emerging osteotoxicant: Mechanistic insights from osteoblasts and zebrafish models.
Changes of N(6)-methyladenosine modification and unfolded protein response in renal cell injury induced by cadmium.
Targeted inhibition of MLKL-mediated necroptosis attenuates chronic arsenite exposure-induced lung injury.
Discovery of degrader for FLT3, GSPT1 and IKZF1/3 proteins merging PROTAC and molecular glue targeting FLT3-ITD mutant acute myeloid leukemia.
Functional metabolomics revealed pyroglutamic acid may play a key role in idiopathic pulmonary fibrosis.
Ursolic acid improves cognitive impairment in type 2 diabetic mice by preventing complement 3 secretion and neuropathy.
Effects of wild-type and mutant TDP-43 on cognitive function and hippocampal neurons in mice.
Nephroprotective mechanism of Kunkui Baoshen decoction in diabetic kidney disease: Targeting the HERC2/NCOA4-mediated autophagy-dependent ferroptosis pathway.
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence.
Aβ-damaged neural stem cells migration and differentiation through Wnt3a/β-catenin pathway: Protective effects of 17β-E2.
IL-1β(+) tumor-associated macrophages accelerate glioblastoma progression by amplifying the PGE2-EP4 signaling.
The Effects and Mechanisms of Ti-Fu-Kang Decoction in Alleviating Central Fatigue: Insights from Network Pharmacology and Metabolomics.
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
Lysosome stress response and mitochondria injury are the earliest detectable alteration in FSGS.
Salvigenin inhibits gastric cancer progression by suppressing the EGFR/PI3K/AKT pathway.
Blockade of TGF-β1/Smad3 signaling pathway by Bovine Milk-derived extracellular vesicles ameliorates skin fibrosis in systemic sclerosis mice.
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repair.
S100A9 inhibition ameliorates HFpEF by modulating mitochondrial fission and oxidative stress.
Knockdown of Nr4a3 mitigates acute pancreatitis-induced injury by modulating Btg2 to reduce oxidative stress, mitochondrial damage, and apoptosis.
Bta-miR-199a-3p in embryonic bovine lung cells-derived extracellular vesicles enhances pro-inflammatory cytokine expression in macrophages via DUSP5 upregulation during Mycoplasma bovis infection.
Vilazodone ameliorates senescence-related Alzheimer's disease like symptoms by targeting Plau to induce autophagy in senescent cells.
Corilagin alleviates radiation enteritis through caspase-1/gasdermin D-dependent pyroptosis by targeting aldo-keto reductase family 1 member C2 via glutathione metabolism.
Tangeretin protects the kidney from ischemia-reperfusion injury by inhibiting inflammatory response through downregulation of MAOA.
Monoclonal antibody SZ168 targeting Podoplanin alleviates neuroinflammation by suppressing microglial Pyroptosis in cerebral Hemorrhage.
Cannabinoid CB1 receptor in dopaminergic circuit from ventral tegmental area to nucleus accumbens links trait anxiety with reward learning.
Dysregulated Protein s-Nitrosylation Promotes Nitrosative Stress and Disease Progression in Heart Failure With Preserved Ejection Fraction.
Albiflorin attenuates post-myocardial infarction cardiac fibrosis through inhibiting the RAS-ERK/MAPK signaling pathway.
Andrographolide attenuates oxidative stress and apoptosis in osteoporosis rats via MEK/ERK and Beclin-1/ATG-5-mediated autophagy pathway.
Fusarium solani Activates PANoptosis and Modulates Immune Response in Fungal Keratitis.
PARP1 promoter hypermethylation promotes arsenic-induced skin damage by driving telomere dysfunction-mediated keratinocyte senescence.
ATF3 as a molecular nexus linking ferroptosis regulation to sarcopenia pathogenesis via PI3K/Akt pathway activation.
Crinis Carbonisatus-Derived Carbon Dot Suspension Alleviates Temporal Lobe Epilepsy.
METTL3-mediated m6A modification promotes ferroptosis in adenomyosis through GPX4 in a YTHDF1-dependent manner.
LncRNA MEG3 Regulates Glaesserella parasuis-Induced Apoptosis of Porcine Alveolar Macrophages via Regulating ssc-miR-135/CASP8 Axis.
A Pan-Enterovirus Natural Product Inhibitor Targeting a Unique Allosteric Site on the Viral 3C Protease.
Novel SPTB Variations Cause Hereditary Spherocytosis With Cholangiolithiasis and Severe Intrahepatic Cholestasis.
Targeting CLK1/SRSF7 axis-dependent alternative splicing sensitizes pancreatic ductal adenocarcinoma to chemotherapy and immunotherapy.
Machine learning analysis facilitates the identification of liver biomarkers in postmortem diagnosis of heat stroke.
NNMT enhances invasive and migratory capacity of keloid fibroblasts and M2 macrophage polarization.
Oncogenic Role of PTPN14 in Pancreatic Cancer Through β-Catenin/NF-κB Pathway Activation.
Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway.
ATF4 transcriptionally activates NUPR1 to promote ferroptosis in chondrocytes and osteoarthritis development.
Counteracting lysosome defects alleviates the cellular senescence of Hutchinson-Gilford progeria syndrome.
TRAF6 Exerts Tumor-Promoting Effects via Genetic and Autophagic Modulation in Gastric Cancer.
Integrated transcriptome and single-cell RNA sequencing analysis revealed the prognostic significance of GBP4 in pancreatic adenocarcinoma.
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Modeling Lipopolysaccharide-Elicited Inflammation Using 3D Mouse Gastric Organoids.
METTL16 promotes progression of clear cell renal cell carcinoma via up-regulating N6-methyladenosine modification of KLK4 mRNA.
Dysregulation of immune checkpoint LAG3 in mice exposed to silica.
Pinocembrin ameliorates non-alcoholic fatty liver disease by activating Nrf2/HO-1 and inhibiting the NF-κB signaling pathway.
Astragaloside IV Alleviates Cisplatin Chemotherapy-Induced Nephrotoxicity via Modulation of Nrf2/HO-1/NF-κB Pathway and Reversal of EMT Process.
Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.
Salvianolic Acid A Mitigates Osteoporotic Bone Loss by Repressing Reactive Oxygen Species via the Nrf2-HO-1 Pathway.
Bone morphogenetic protein 1 as a macromolecular pan-cancer biomarker modulating the immune microenvironment and malignant phenotypes in glioblastoma.
Structural characteristics of a fructan-type polysaccharide from Asparagus cochinchinensis rhizome and its anti-osteosarcoma activity mediated via macrophage polarization.
RIPK4-p53 interaction drives aflatoxin B1-induced renal mitochondrial apoptosis via Ser15 phosphorylation: A CRISPR-Cas9 mechanistic study.
Myosin heavy chain 9 is a critical host factor for Japanese encephalitis virus entry and replication in U251 cells.
Phase separation of CgSCE3 is required for heat stress resistance and pathogenicity of Colletotrichum gloeosporioides.
FBXL16 regulates TAMs recruitment by mediating cytokine release in gliomas.
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
Dietary BCAA supplementation counteracts the beneficial effects of long-term aerobic exercise against obesity and associated metabolic disorders by suppressing FGF21 expression.
Network toxicology and cell experiments reveal the mechanism of saikochromone A-induced hepatotoxicity.
Lysyl oxidase-like 2 inhibition alleviates subretinal fibrosis in neovascular age-related macular degeneration model.
Mogroside V restores glycolytic function via LDHA promoter demethylation independent of alternative splicing in PCOS granulosa cells.
E3 ligase SINAT5 mediates ERF113 stability and negatively governs the module of ABI5-like-ERF113 in regulating banana fruit ripening.
MiR-126-5p Derived From Bone Marrow Mesenchymal Stem Cell Exosomes Promotes Skeletal Muscle Regeneration by Regulating FBXO32/MyoD Signaling.
SETDB2 participates in iron metabolism in esophageal squamous cell carcinoma via H3K9me3-mediated TFRC silencing.
STN1 Shields CTC1 From TRIM32-Mediated Ubiquitination to Prevent Cellular Aging.
Hyperactivation of the m(6)A demethylase FTO to down-regulate SLC7A11/xCT-mediated redox homeostasis and epigenetic remodeling in facial infiltrating lipomatosis.
Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway.
Programmed cell death ligand 1 mediates antigen presentation, apoptosis, necrosis, and inflammatory response in Klebsiella pneumoniae-infected macrophages.
The RNA-binding protein RBM39 scaffolds an m⁶A-dependent RNA decay complex that destabilizes Tat transcripts and restricts HIV-1 reactivation.
Collagen peptides from Skipjack tuna (Katsuwonus pelamis) bones: Composition, characterization, and mechanism of high-fat diet-induced NAFLD amelioration.
Eurotium Cristatum fermented instant dark tea prevents obesity and promotes adipose thermogenesis via modulating the gut microbiota.
Aristolochic acid I promotes renal tubulointerstitial fibrosis by activating the mannan-binding lectin serine protease 1-complement system.
Synthetic organochlorines exert bone anabolic activity by modulating CCN3 signaling in osteoblasts.
TRIB3 promotes endometrial cancer progression through interacting with E2F1 and enhancing PKM2-mediated tumor glycolysis.
NSUN6 Promotes Gastric Cancer Progression by Stabilizing CEBPZ mRNA in a m(5)C-Dependent Manner.
Blocking Fpr3 ameliorates osteoarthritis by inhibiting NLRP3-mediated chondrocyte pyroptosis.
Olaparib synergy screen reveals Exemestane induces replication stress in triple-negative breast cancer.
Activation of IRF2 signaling networks facilitates podocyte pyroptosis in lupus nephritis.
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.
Inhibition of spreading depolarizations by targeting GABA(A) receptors and voltage-gated sodium channels improves neurological deficits in rats with traumatic brain injury.
Biotransformation of steroid hormones by intestinal fungi and their special cytotoxicity on HeLa cancer cells.
Parthenolide alleviates doxorubicin-induced cardiotoxicity via regulation of Cyp1a1 and Nppa and suppression of NLRP3 inflammasome.
Salvigenin mitigates neuronal ferroptosis by binding to PI3K and enhancing the interaction between VCP and PI3K in the repair of spinal cord injury.
Benzoylpaeoniflorin alleviates ulcerative colitis by inhibiting ferroptosis through targeting phosphogluconic dehydrogenase.
Early postnatal overnutrition as a contributor to metabolic dysregulation: Insights into hepatic epigenetic mechanisms.
O-GlcNAcylation of PRDX1 enhances its stability and promotes liver cancer progression via activating LRP6-mediated Wnt signaling.
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
CX-5461 inhibits cell proliferation and induces ferroptosis of colorectal cancer cells by inactivating Nrf2 pathway.
KSRP-mediated Wnt/β-catenin activation promotes follicular thyroid cancer progression and stemness.
Crosstalk between DNA damage and cGAS-STING immune pathway drives neuroinflammation and dopaminergic neurodegeneration in Parkinson's disease.
Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma.
Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma.
EGFR Targeted Liposomal PROTAC Assisted With Epigenetic Regulation as an Efficient Strategy for Osimertinib-Resistant Lung Cancer Therapy.
Polycystin-1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1-Dependent Microfilament Remodeling.
Baicalin alleviates oxidative stress in DF-1 cell line via the Mfn2/MAMs/Ca (2+) pathway.
Functional characterization of LSM12 as a driver in uveal melanoma oncogenesis.
Targeting FAM134B-DDX3X axis inhibiting AKT signaling in hepatocellular carcinoma.
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
Recombinant live attenuated measles virus-based vaccines inducing comprehensive protection against Ebola and Marburg viruses.
Small nucleolar RNA host gene 1 (SNHG1) facilitates gemcitabine chemosensitivity in gallbladder cancer by regulating the miR-23b-3p/phosphatase and tensin homolog (PTEN) pathway.
Betulinic acid attenuates lipopolysaccharide-induced cardiac injury by promoting mitophagy with enhancing PINK1/Parkin and suppressing BNIP3.
Icariside II ameliorates slow transit constipation by inhibiting macrophage polarization and suppressing the cGAS-STING pathway.
VSIG2 hinders gastric cancer progression by suppressing ANXA2-mediated NF-κB pathway activation.
Integrated summary data-based Mendelian randomization and colocalization analysis reveals TNNT3 as a target of Deer-Antler-Ginseng-formula for triple-negative breast cancer.
Osteocyte Neuropeptide Y Aggravates Bone Loss in OVX Mice by Inhibiting Preosteoclast Proliferation and PDGF-BB-Induced Type H Vessel Formation Through PI3K/Akt Signaling Pathway.
New perspective on postmortem meat quality changes of Esox Lucius: The role of mitophagy-mediated ferroptosis pathway.
Active-targeting biomimetic nanosystem for prostate cancer enhances radiotherapy efficacy by inducing ferroptosis.
The kinesin motor Kif9 regulates centriolar satellite positioning during interphase.
Long-read sequencing reveals HBV integration patterns and oncogenic impact on early-onset hepatocellular carcinoma.
Fragile X mental retardation 1 gene FMR1 promotes proliferation, migration, and invasion of gastric cancer cells via c-MYC.
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
Dexmedetomidine enhances anastomotic healing partly via the Wnt/β-catenin pathway in a rat model of colon surgery.
TRIM25 degrades BRD7 protein stability through the ubiquitin proteasome pathway to promote breast cancer progression and paclitaxel resistance by activating YB1/Bcl-2 transcription axis.
Protein deglycase DJ-1 deficiency aggravates acute viral myocarditis by promoting apoptosis via reducing Dusp1 expression.
MYC-mediated transcriptional control of splicing factors promotes RNA splicing in activated B lymphocytes.
RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease.
FeaSion decodes the regulatory landscape and functional diversity of RNA polymerase II CTD phosphorylation.
ADGRG6 Promotes Pancreatic Adenocarcinoma Progression Through the NF-κB/STAT6 Axis and Modulation of the Tumor Immune Microenvironment.
Identifying NDUFB2 as a prognostic biomarker for glioblastoma through an exploratory analysis of an anesthesia-related gene signature.
Development of Knockout Cardiac Muscle Cell Lines Using Integrase-Deficient Lentivirus-Mediated CRISPR/Cas9 Gene Editing.
Investigating the impact of MCTP2 on immune suppression and drug resistance in glioblastoma.
Preliminary exploration of the role of fibrinogen-like protein 2 in neuroblastoma.
mRNA caps accumulate in stress granules and are essential for their formation.
GDF11 alleviates glucocorticoid-induced osteonecrosis of the femoral head by regulating angiogenesis via the PI3K-AKT-eNOS pathway.
Cancer-associated adipocytes mediate CD8(+)T cell dysfunction via FGF21-driven lipolysis.
Eucommia ulmoides Oliver (Duzhong) extract ameliorates cerebral ischemic stroke in mice by remodeling intestinal microbiota and metabolites.
Positive feedback loop of IGF2BP3/IL6ST/STAT3 facilitates malignant progression in colorectal cancer.
Solvent-induced partial cellular fixation decodes proteome-wide drug targets and downstream pathways in living cells.
Matrine activates high xenophagy to inhibit enterovirus replication.
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Rosmarinic acid alleviates doxorubicin-induced cellular senescence and cardiotoxicity by targeting the 14-3-3/Foxo1 signaling axis.
Kaempferol ameliorates BMSCs senescence in postmenopausal osteoporosis by targeting Sp1 to activate FUNDC1-mediated mitophagy.
Syringin attenuates Alzheimer's disease-associated neuroinflammation by inhibiting NLRP3 inflammasome activation.
Unveiling tectorigenin: A novel ferroptosis inducer targeting EGFR in bladder cancer.
Biochanin A alleviates endothelial cell senescence via epigenetic regulation of the HDAC1/H3K4me3/NFKB1 axis.
Euchrenone A10 attenuates septic lung injury though S100A8/A9-dependent TLR4/MyD88/NF-κB signaling.
Ailanthone targets mitophagy-loaded SIRT4 to facilitate the deacetylation of HIF1α, triggering oxidative stress for gastric carcinoma treatment.
Liu-Jun-Zi decoction alleviates metabolic dysfunction-associated steatohepatitis by modulating myogenic irisin mediated skeletal muscle-liver crosstalk.
Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in fungi.
USP30-AS1 Dictates Breast Cancer Cell Fate and Chemoresistance via a miR-3646/FZD7/Wnt/β-Catenin Circuit.
MiR-503-5p mediates cell cycle arrest and fibrosis of peritoneal mesothelial cells with a high peritoneal solute transport status.
Directed rescue strategy for enhanced implant osteointegration in aged rats.
Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders.
Efficacy and safety of intrathecal human umbilical cord-derived mesenchymal stromal cell therapy for bone cancer pain: a preclinical study.
Hua Feng Dan protective effect on ischemic stroke through AKT and ERK pathway.
Trofinetide Improves Cognitive Function in APP/PS1 Mice by Suppressing Inflammation and Apoptosis.
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
Mutant NPM1 modulates PDCD4 ubiquitination degradation and facilitates leukemogenesis.
A SWI/SNF complex-related genes signature predicts prognosis and immune infiltration in ccRCC with KCNK5 as a novel biomarker.
MAGEA11 promotes GC proliferation, migration, and invasion through activation of E2F1 transcriptional activity.
Neuroserpin: A Potential Neuroprotective Agent in Mild Neonatal Hypoxic-Ischaemic Encephalopathy.
Effect of OASL on oxaliplatin-induced immunogenic cell death in gastric cancer via the cGAS-STING signaling pathway.
Integrative machine learning-driven prognosis and immunotherapy stratification via lactylation-associated gene in ovarian cancer.
KIF11 variants in familial exudative vitreoretinopathy leading to mTORC1 overactivation and impaired cell cycle progression.
Sodium hexametaphosphate mitigates calcium oxalate stone formation by modulating crystallization and maintaining PPARα signaling.
Perinuclear theca protein FNDC8 interacts with CCIN and ACTL7A to ensure proper sperm head shaping during spermiogenesis.
NAT10 induces N4-acetylcytidine modification of AdipoR1-mediated mitochondrial biogenesis against endothelial-to-mesenchymal transition in hypertension.
PTPRK promotes resiniferatoxin-induced postherpetic neuralgia via activating DUSP1/p38 MAPK signaling pathway in dorsal root ganglia.
Knockdown of PATZ1 alleviates chronic heart failure through the USP22/HIF-1α axis.
Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss.
Assessing the toxicological effects of exposure to environmental pollutants PET-MPs on vascular diseases: insights from network toxicology, molecular docking, molecular dynamics, and experimental validation.
Antimony exposure induces bladder cancer metastasis via activation of the SUMOylation-dependent TGF-β/Smad2/3 axis.
Ceftriaxone ameliorates tau phosphorylation and mislocalization in APP/PS1 AD mice by inhibiting endoplasmic reticulum stress.
Key targets of brain-gut coordination in Wuzhuyu decoction treating chronic migraine based on proteomics.
Farnesoid X Receptor Agonist INT-787 Inhibits Hepatic Mitochondrial Dysfunction in a Diet-Induced ob/ob Mouse Model of MASH.
INHBA promotes chemoresistance in pancreatic cancer by enhancing CTPS1 stability and mediating pyrimidine metabolism.
Aβ impairs bone vascular homeostasis in APP/PS1 mice via disrupting the mitochondrial fission-efferocytosis axis in macrophages.
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
Empagliflozin alleviates hepatic ischemia-reperfusion injury by inhibiting c-Myc through the JAK1-STAT3 signaling pathway.
AMSC-EVs attenuate acute kidney injury through TXNIP-IKKα/NFκB signaling-mediated renal CX3CR1(+) macrophage polarization.
Comprehensive analysis of ALYREF gene expression and its correlation with immunotherapy efficacy and circulating tumor cells in bladder cancer.
Discovery of Cdc20/Hsp90 Dual-Target Inhibitors with Potent Antitumor Activity for Therapy of Acquired Resistant Melanoma.
NAP1L4 in hepatocellular carcinoma progression and treatment from gene expression to clinical impact.
CpG ODN Activates TLR9 and Upregulates TLR3 via the p38 MAPK-ATF3 Signaling Axis to Synergistically Enhance Dendritic Cell Vaccine Efficacy.
S100A6 Regulated by PATZ1 Promotes Liver Fibrosis by Activating Hepatic Stellate Cells.
NDC80 promotes epithelial to mesenchymal transition of esophageal squamous cell carcinoma through macrophages polarization and PI3K/AKT pathway activation.
Neuroglobin-promoted autophagy inhibits the proliferation, migration and invasion of human glioblastoma cells through the EGFR/PI3K/AKT/mTOR signaling pathway.
Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota homostasis in rats.
Ferroptosis-driven neurobehavioral impairment in zebrafish embryos: Mechanistic links to developmental dibutyl phthalate exposure.
Potentiated fractalkine signaling axis affects neuroinflammation in 1,2-dichloroethane- intoxicated mice via divergent modulating ways on microglial hyperactivation.
Effects of EP-1 exposure during lactation on the emotion, social behavior, gonadal metabolomics, and related receptors in the brains of adult offspring in Kunming mice.
Pantothenic acid-mediated inhibition of microglial inflammation via the JAK2/STAT3 pathway enhances motor function recovery after Spinal cord injury.
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Activation of TRPA1 prevents metabolic dysfunction-associated steatotic liver disease in diet-induced obese mice through stimulating the AMPK/CPT1A signaling pathway.
Modulation of Osteogenic Differentiation by CYBB in Osteoporotic Models.
Isowalsuranolide targets TrxR1/2 and triggers lysosomal biogenesis and autophagy via the p53-TFEB/TFE3 axis.
Beta-aminoisobutyric acid attenuates doxorubicin-induced cardiotoxicity through the adenosine 5'-monophosphate-activated protein kinase-mediated pathway.
Polystyrene microplastics trigger colonic inflammation in rats via the TLR4/NF-κB/COX-2 pathway and modulation of intestinal microbiota.
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
Methyltransferase-like enzyme 14 exacerbates retinal ganglion cell damage and diabetic retinopathy through N6-methyladenosine-dependent upregulation of pleckstrin homology domain and leucine rich repeat protein phosphatase 2.
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
Human umbilical cord mesenchymal stem cells improve bone marrow hematopoiesis through regulation of bone marrow adipose tissue.
The Role of CXCL13 in GC-1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Through JAK2/STAT3 Signaling Pathway.
Tetrahydropalmatine promotes macrophage autophagy by inhibiting the AMPK/mTOR pathway to attenuate atherosclerosis.
Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.
FOXC1 Aggravates the Ischemia-Reperfusion Induced Injury in Renal Tubular Epithelial Cells by Activating NF-κB/NLRP3 Signaling.
Dihydroartemisinin Targets the NFIC/FBN1 Cascade to Enhance Wound Healing in Chronic Skin Ulcer by Inhibiting Fibroblast Ferroptosis.
HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB.
Activation of sigma 1 receptor attenuates doxorubicin-induced cardiotoxicity by alleviating oxidative stress, mitochondria dysfunction, ER stress-related apoptosis, and autophagy impairment.
HuMSCs-derived exosomal YBX1 participates in oxidative damage repair in granulosa cells by stabilizing COX5B mRNA in an m5C-dependent manner.
Exosomes derived from baicalin‑pretreated mesenchymal stem cells mitigate atherosclerosis by regulating the SIRT1/NF‑κB signaling pathway.
Lactoferrin ameliorates cognitive impairment in D-galactose-induced aging mice by regulating the PI3K/Akt/mTOR signaling pathway and the microbiome-gut-brain axis.
MTA1-DT promotes endometrial cancer growth by modulating G2/M-related gene transcription via PURα.
SERTAD3 interacts with porcine reproductive and respiratory syndrome virus nonstructural protein 9 and inhibits virus replication.
Salidroside attenuates NASH through regulating bile acid-FXR/TGR5 signaling pathway via targeting gut microbiota.
Matrix metallopeptidase 2-responsive curcumin-loaded nanoparticles-induced signal transducer and activator of transcription 3 inhibition suppresses glioblastoma multiforme growth via enhancing nuclear factor erythroid 2-related factor 2 activity.
Z-VAD(OMe)-FMK suppresses Seneca Valley Virus replication by targeting the active sites of the 3C protease.
RAB4B and Japanese encephalitis virus E protein interaction is essential for viral entry in early endosomes.
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Konjac glucomannan/sodium alginate/ε-poly-l-lysine hydrogel promotes esophageal and colonic wound healing.
S5092 inhibit ASFV infection by targeting the pS273R protease activity in vitro.
Extracellular vesicles engineered to directly target encephalomyocarditis virus ameliorates multi-organ viremia in a lethal infection model.
Paeonol Improves Cardiac Remodelling in MI Mice by Suppressing NOX2 mRNA Expression to Mitigate Oxidative Stress and Mitochondrial Dysfunction.
UBE2T is a diagnostic and prognostic biomarker for endometrial cancer.
V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging.
Baicalin restores dopamine homeostasis in the ADHD model by regulating DAT-VMAT2 transport imbalance through activation of the Nrf2/Keap-1/HO-1 pathway.
Lingguizhugan Decoction improves chronic heart failure by synergistically modulating ?1-AR/Gs/GRKs/?-arrestin signaling bias.
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Genome-scale CRISPR screen identifies TMEM198 driving double membrane vesicle formation in swine alphacoronavirus and murine betacoronavirus infected cells.
Restoration of lysosomal function attenuates autophagic flux impairment in nucleus pulposus cells and protects against mechanical overloading-induced intervertebral disc degeneration.
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Tetrahedral DNA Nanostructure-Modified Nanocoating for Improved Bioaffinity and Osseointegration of Titanium.
EPA-enriched lipid from Apostichopus japonicus byproducts mitigates UVB-induced oxidative stress and inflammation by gut-skin axis.
Circular RNA ATP9A Stimulates Non-small Cell Lung Cancer Progression via MicroRNA-582-3p/Ribosomal Protein Large P0 Axis and Activating Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.
Compound C1 reduced inflammation and activated autophagy in alveolar macrophages in mice.
Specnuezhenide and ecliptasaponin A from Ligustrum lucidum Ait and Ecliptae Herba improved premature ovarian failure by targeting the ESR1.
Shenqi granules enhance recovery from cerebral ischemia-reperfusion injury by modulating tryptophan and tyrosine metabolism and activating NFE2L2/NRF2.
Piperlongumine alleviates viral myocarditis by inhibiting pyroptosis through NF-κB pathway.
Liensinine overcomes EGFR-TKI resistance in lung adenocarcinoma through DRP1-mediated autophagy.
Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade.
Effective compound combination of Bufei Yishen formula ameliorates PM2.5-induced COPD by inhibiting mitochondrial oxidative stress through SIRT3-mediated FOXO3 deacetylation.
Procyanidins inhibit alphacoronavirus infection by reducing interferon antagonism.
Study on the mechanism of Trichosanthes kirilowii Maxim. against COPD based on serum chemical composition analysis, network pharmacology, and experimental study.
NOP2-Mediated m5C Methylation Modification of LMNB2 mRNA Facilitates Colorectal Cancer Progression.
LAMP3 exacerbates autophagy-mediated neuronal damage through NF-kB in microglia.
Dectin-1 participates in neuroinflammation and dopaminergic neurodegeneration through synergistic signaling crosstalk with TLR4.
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization.
AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple-Negative Breast Cancer.
NEK2 Contributes to the Protection Against Cryptorchidism Outcomes.
Novel Phenoxyacetic Acid (4-Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site.
Dysfunctional terminal differentiation of satellite cells in the wooden breast muscle of Ross 308 broiler chickens.
RAGE/AP-1/OTR signaling pathway in rat hippocampus DG involved in CUS induced depressive-like behaviors.
Mechanistic Insights into the Anti-Hepatocellular Carcinoma Effects of ACY-1215: p53 Acetylation and Ubiquitination Regulation.
A novel dual CCK/ GLP-1 receptor agonist ameliorates cognitive impairment in 5 × FAD mice by modulating mitophagy via the PINK1/Parkin pathway.
Compound J27 alleviates high-fat diet-induced metabolic dysfunction-associated steatotic liver disease by targeting JNK.
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
The dual effects of propofol down-regulating PD-L1 expression and inhibiting autophagy to reduce cerebral ischemia reperfusion injury.
Electroacupuncture ameliorates cognitive impairment and white matter injury in vascular dementia rats via activating HIF-1α/VEGF/VEGFR2 pathway.
Pentraxin 3 promotes the expression of pro-inflammatory cytokines and the migration of macrophages in myocarditis.
Endoplasmic reticulum protein 29 negatively regulates platelet functions and thrombosis in mice.
Black Phosphorus-Loaded Gelatin Methacryloyl Hydrogels Enhance Angiogenesis via Activation of the PEAK1-MAPK Pathway.
Erianin inhibits cell migration and induces apoptosis by inhibiting VEGF-α/PI3K/AKT signaling pathway in malignant melanoma.
Fibulin-1 deficiency alleviates liver fibrosis by inhibiting hepatic stellate cell activation via the p38 MAPK pathway.
Ferroptosis Activation Contributes to Kidney Aging in Mice by Promoting Tubular Cell Senescence.
Lithium with environmentally relevant concentrations interferes with mitochondrial function, antioxidant response, and autophagy processes in Daphnia magna, leading to changes in life-history traits and behavior.
Design, synthesis and optimization of Apcin analogues as Cdc20 inhibitors for triple-negative breast cancer therapy.
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
Modulation of senescent Lepr(+) skeletal stem cells via suppression of leptin-induced STAT3‒FGF7 axis activation alleviates abnormal subchondral bone remodeling and osteoarthritis progression.
Bardoxolone methyl suppressed colorectal cancer cells in vitro by inhibiting the PI3K signaling pathway.
KRT6A Restricts Influenza A Virus Replication by Inhibiting the Nuclear Import and Assembly of Viral Ribonucleoprotein Complex.
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Enterovirus 71 Induces Mitophagy via PINK1/Parkin Signaling Pathway to Promote Viral Replication.
A Novel Role of Adipokine 'Intelectin-1': Ameliorating Renal Fibrosis Through Inhibition of Renal Tubular Epithelial Cell Senescence.
LCLAT1 as a Potential Biomarker for Predicting Clinical Prognosis, Tumor Immunity, and Therapeutic Efficacy in Hepatocellular Carcinoma.
Mechanism of adenosine monophosphate-activated protein kinase promoting lower extremity varicose veins development via cytoskeletal dynamics.
Hippocampal Proteomics Reveals the Novel Molecular Profiling of Postnatal Lead (Pb) Exposure on Autism-like Behaviors.
TRPC6-targeted dexamethasone nanobubbles with ultrasound-guided theranostics for adriamycin-induced nephropathy.
A critical role for IL-21/IL-21 receptor signaling in isoproterenol-induced cardiac remodeling.
The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma.
Calpain1 inhibition enhances autophagy-lysosomal pathway and ameliorates tubulointerstitial fibrosis in Nephronophthisis.
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Activation of the MEK1-CHK2 axis in macrophages by Staphylococcus aureus promotes mitophagy, resulting in a reduction in bactericidal efficacy.
Copper-Induced DRP1 Activation Disrupts Mitochondrial-Lipid Droplet Contact to Promote Hepatic Steatosis.
Aryl Hydrocarbon Receptor-Dependent miRNA-382-5p Mediates the Classical Pyroptosis Induced by Foodborne Benzo(a)pyrene through Targeting IκB in Liver.
Tylophora yunnanensis extract inhibits cholesterol biosynthesis to suppress triple negative breast cancer.
IGF-1 signaling pathway activation promotes axonal regeneration and repair: A mechanism study on catalpol-induced functional recovery after ischemic stroke.
Cryptotanshinone alleviates cerebral ischemia reperfusion injury by regulating ferroptosis through the PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway.
Pyrotinib promotes the antitumor effect of T-DM1 by increasing drug endocytosis in HER2-positive breast cancer.
NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation.
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway.
Elevated CEP72 expression facilitates the progression of hepatocellular carcinoma and is associated with unfavorable outcomes.
Dihydroartemisinin alleviates diethylnitrosamine-induced hepatocarcinogenesis by targeting a novel MAZ/TRIM50 axis.
Therapeutic potential of CHI3L1 in osteoarthritis: Inhibition of cartilage matrix degradation and inflammation through TLR4-MAPK-STAT1 pathway.
LncRNA SNHG15 promotes angiogenesis and improves cardiac repair after myocardial infarction through MiR-665-mediated KDR expression.
Integrative Single-Cell and Bulk RNA Sequencing Identifies a Glycolysis-Related Prognostic Signature for Predicting Prognosis in Pancreatic Cancer.
The oncogenic role of TIMM8A in cancer and the mechanistic insights into the function in breast cancer cells.
Erucin Alleviates Cardiac Hypertrophy by Improving Mitochondrial Function via Nrf2-Sirt3 Pathway.
ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity.
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
FBXO10 Drives Hepatocellular Carcinoma Proliferation via K63-Linked Ubiquitination and Stabilization of FRMPD1.
CIRBP Enhances the Function of Yak Cumulus Cells by Activating AMPK/mTOR-Mediated Mitophagy.
Integration of network pharmacology, transcriptomics, and experimental verification to investigate the mechanism of action of cepharanthine hydrochloride against prostate cancer.
Taletrectinib promotes pyroptosis in colorectal carcinoma via SRC/AKT/mTOR axis inhibition.
Single-cell imaging of N4-acetylcytidine-modified RNA using fluorine metabolic labeling mediated proximity ligation assay.
Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes.
Identification of m5C RNA modification-related gene signature for predicting prognosis and immune microenvironment-related characteristics of heart failure.
MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer.
Selenoprotein K Confers Protection against Iron Dyshomeostasis-Related Neurotoxicity by Regulating the Palmitoylation of TfR-1.
Inhibition of Farnesoid-x-receptor signaling during abdominal sepsis by dysbiosis exacerbates gut barrier dysfunction.
Caveolin-1 negatively regulates the calcitonin receptor-like receptor and neuroinflammation in a female mouse model of migraine.
Iron Replacement Attenuates Hypoxic Pulmonary Hypertension by Remodeling Energy Metabolism via Regulating the HIF2α/Mitochondrial Complex I, III/ROS Axis.
DJ-1 deficiency and aging: dual drivers of retinal mitochondrial dysfunction.
Silencing of LncRNA XIST Suppressed Tumor Growth and Metastasis in Papillary Thyroid Carcinoma by Modulating miR-204/FN1 Axis.
Study on Cellular Mechanism of Improving Inflammatory Effect of Gastrodin.
Microcystin-LR induces lung injury in mice through the NF-κB/NLRP3 pathway.
B cell dysfunction in thalamus and brainstem involvement and high lactate caused by novel mutation of EARS2 gene.
Amelioration of Acetaminophen-Induced Hepatic Oxidative Stress and Inflammation by RNAi Targeting Cyp2e1 In Vivo.
To verify the biological characteristics of disulfidptosis associated gene ADORA2B in esophageal cancer.
Synergistic regulation of DACH1 stability by acetylation and deubiquitination promotes colorectal cancer progression.
Inhibition of TPI1 Sensitizes Cisplatin-Resistant Oral Cancer to Ferroptosis.
Impaired Mitophagy Contributes to Pyroptosis in Sarcopenic Obesity Zebrafish Skeletal Muscle.
Outer membrane vesicles of Porphyromonas gingivalis impede bone regeneration by inducing ferroptosis via the Hippo-YAP signaling pathway.
Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions.
LncRNA NEAT1 participates in diminished ovarian reserve by affecting granulosa cell apoptosis and estradiol synthesis via the miR-204-5p/ESR1 axis.
Inhibition of hsa_circ_0003314 contributes to trophoblast cell migration and invasion and inhibits pyroptosis in preeclampsia.
Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway.
Ursolic acid suppresses ferroptosis by modulating Th17/Treg balance and gut dysbiosis in experimental autoimmune thyroiditis rats.
Identification of liver proteins as biomarker for postmortem diagnosis of heat stroke through proteomics.
METTL3 promotes osteogenesis by regulating N6-methyladenosine-dependent primary processing of hsa-miR-4526.
Trimethylamine N-oxide induces cardiac diastolic dysfunction by down-regulating Piezo1 in mice with heart failure with preserved ejection fraction.
ZLN005, a PGC-1α agonist, delays photoreceptor degeneration by enhancing mitochondrial biogenesis in a murine model of retinitis pigmentosa.
Endoplasmic reticulum stress and forkhead box protein O1 inhibition mediate palmitic acid and high glucose-induced β-cell dedifferentiation.
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Atractylenolide I Inhibits Nicotine-Induced Macrophage Pyroptosis and Alleviates Atherogenesis by Suppressing the TLR4/ROS/TXNIP/NLRP3 Pathway.
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury.
Targeting GPR84 to alleviate acute immune-mediated liver injury.
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Cellular SLC35B4 promotes internalization during influenza A virus entry.
Human umbilical cord mesenchymal stem cell therapy for atopic dermatitis through inhibition of neutrophil chemotaxis.
ROS-responsive dextran-benzeneboronic acid pinacol ester micelles encapsulating edaravone for the treatment and mechanism of cerebral ischemia-reperfusion injury.
JAK2/STAT3/HMGCS2 signaling aggravates mitochondrial dysfunction and oxidative stress in hyperuricemia-induced cardiac dysfunction.
Gut microbiota-derived glutathione from metformin treatment alleviates intestinal ferroptosis induced by ischemia/reperfusion.
Dysregulation of miR-106a-5p/PTEN axis associated with progression and diagnostic of postmenopausal osteoporosis.
Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms.
The potential of secretogranin V as a prognostic biomarker in non-small cell lung cancer.
Bufei Yishen formula alleviates airway epithelial cell senescence in COPD by activating AMPK-Sirt1-FoxO3a pathway and promoting autophagy.
Synaptic and cognitive impairment associated with L444P heterozygous glucocerebrosidase mutation.
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Phillyrin from Forsythia suspensa suppresses the proliferation, angiogenesis, and metastasis of colorectal cancer via targeting CD147.
Dendrobium nobile lindl extract modulates integrin αIIbβ3-mediated signaling pathways to inhibit platelet activation and thrombosis.
Exploration of the pharmacological substance basis and efficacy evaluation of fufang she-she-cao (Hedyotis diffusa formula) in repressing gastric cancer.
Unravelling lumbar disc herniation severity beyond MRI : integrated transcriptomic and metabolomic analyses highlight glycerophospholipid metabolism and inform a machine-learning diagnostic model: a pilot study.
Enhanced Osteogenic Activity of a Titanium Mesh Modified with Magnesium-Doped Nanowires for Peri-Implant Guided Bone Regeneration: In Vitro and In Vivo.
HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression.
Aberrant phase separation drives membranous organelle remodeling and tumorigenesis.
Formononetin prevents intestinal injury caused by radiotherapy in colorectal cancer mice via the Keap1-Nrf2 signaling pathway.
SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma.
Mechanism of arsenic regulation of mitochondrial damage and autophagy induced synaptic damage through SIRT1 and protective effect of melatonin in HT22 cell.
SNORD9 promotes ovarian cancer tumorigenesis via METTL3/IGF2BP2-mediated NFYA m6A modification and is a potential target for antisense oligonucleotide therapy.
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
HaloPROTAC3 treatment activates the unfolded protein response of the endoplasmic reticulum in nonengineered mammalian cell lines.
BACH1 deficiency improves placental angiogenesis via SLC25A51-mediated mitochondrial NAD(+) transport in intrahepatic cholestasis of pregnancy.
Semaglutide and High-Intensity Interval Exercise Attenuate Cognitive Impairment in Type 2 Diabetic Mice via BDNF Modulation.
A heterodimeric radioligand labeled with gallium-68 targeting fibroblast activation protein.
Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions.
Exploring the mechanism of tiRNA-Val-CAC-002 in the pathogenesis of oral submucous fibrosis.
Long non‑coding RNA ABHD11‑AS1 inhibits colorectal cancer progression through interacting with EGFR to suppress the EGFR/ERK signaling pathway.
Thermal Ageing of Black Garlic Enhances Cellular Antioxidant Potential Through the Activation of the Nrf2-Mediated Pathway.
Allocryptopine Attenuates Inflammatory Responses in Microglial Cells Via TLR4-Dependent NF-κB and p38 MAPK Pathways.
TDP-43/ALKBH5-mediated m(6)A modification of CDC25A mRNA promotes glioblastoma growth by facilitating G1/S cell cycle transition.
Exercise-induced Activation of SIRT1/BDNF/mTORC1 Signaling Pathway: A Novel Mechanism to Reduce Neuroinflammation and Improve Post-stroke Depression.
COPB1 deficiency triggers osteoporosis with elevated iron stores by inducing osteoblast ferroptosis.
The potential role of the SIRT1-Nrf2 signaling pathway in alleviating hidden hearing loss via antioxidant stress.
THRA1/PGC-1α/SIRT3 pathway regulates oxidative stress and is implicated in hypertension of maternal hypothyroid rat offspring.
Assessment of cardiotoxicity induced by PFOS exposure and mechanism research via untarget metabolomics.
BMAL1 improves assisted reproductive technology outcomes in patients with polycystic ovary syndrome by targeting BMP6 and regulating ovarian granulosa cell apoptosis.
Bergapten Ameliorates Renal Fibrosis by Inhibiting Ferroptosis.
Liraglutide improves senescence and ameliorating diabetic sarcopenia via the YAP-TAZ pathway.
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
Polydopamine-functionalized nanohydroxyapatite coated exosomes with enhanced cytocompatibility and osteogenesis for bone regeneration.
Investigating the role of IL-6 in the pathogenesis of systemic lupus erythematosus: Insights from bone marrow mesenchymal stem cells.
E. coli Nissle 1917 improves gut microbiota composition and serum metabolites to counteract atherosclerosis via the homocitrulline/Caspase 1/NLRP3/GSDMD axis.
Eravacycline improves the efficacy of anti-PD1 immunotherapy via AP1/CCL5 mediated M1 macrophage polarization in melanoma.
Aloe-Emodin Improves Mitophagy in Alzheimer's Disease via Activating the AMPK/PGC-1α/SIRT3 Signaling Pathway.
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
Exosomal SphK1 from colorectal cancer cells promotes cancer cell migration and activates hepatic stellate cells.
A nucleocapsid monoclonal antibody based sandwich ELISA for the general detection of both PRRSV-2 and PRRSV-1.
Integrating network pharmacology to investigate the mechanism of quercetin's action through AKT inhibition in co-expressed genes associated with polycystic ovary syndrome and endometrial cancer.
Fatty acid desaturase 2 (FADS2) affects the pluripotency of hESCs by regulating energy metabolism.
Midnolin Correlates With Anti-Tumour Immunity and Promotes Liver Cancer Progression Through β-Catenin.
Chemerin's Role in Endometrial Dysfunction: Insights From Transcriptomic Analysis.
Adiponectin facilitates the cell cycle, inhibits cell apoptosis and induces temozolomide resistance in glioblastoma via the Akt/mTOR pathway.
PYCR1 Promotes Esophageal Squamous Cell Carcinoma by Interacting With EGFR to Affecting the PI3K/Akt/mTOR Signaling Pathway.
Single-cell RNA sequencing and cell-cell communication analysis reveal tumor microenvironment associated with chemotherapy responsiveness in ovarian cancer.
Metformin inhibits EV-A71 and CVA16 infections by regulating TRIB3-SCARB2 axis and activating AMPK.
Carbon monoxide alleviates endotoxin-induced acute lung injury via NADPH oxidase inhibition in macrophages and neutrophils.
Anti-inflammatory Fatty Acid Derivatives From Mangrove-derived Actinomycetes Streptomyces sp.
Fibrinogen degradation products exacerbate alpha-synuclein aggregation by inhibiting autophagy via downregulation of Beclin1 in multiple system atrophy.
LRP1-mediated p-tau propagation contributes to cognitive impairment after chronic neuropathic pain in rats.
Long-term leucine supplementation increases body weight in goats by controlling appetite and muscle protein synthesis under protein-restricted conditions.
MiR-592 Attenuates Tamoxifen Resistance in Breast Cancer Through PIK3CA-Mediated PI3K/AKT/mTOR Signaling Pathway.
Inhibition of autophagy as a novel treatment for neurofibromatosis type 1 tumors.
GPSM1 interacts and cooperates with MMP19 to promote proliferation and EMT in colorectal cancer cells.
Epithelium-derived exosomal dipeptidyl peptidase-4 involved in arecoline-induced oral submucous fibrosis.
DEF6 regulates renal ischemia reperfusion injury through suppressing the WWP2 mediated ubiquitination of PARP1.
Renal tubular S100A7a impairs fatty acid oxidation and exacerbates renal fibrosis via both intracellular and extracellular pathway.
GALNT5 promotes migration and invasion of pancreatic ductal adenocarcinoma cells by activating Erk signaling pathway.
1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells.
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
N-Heterocyclic functionalized chalcone derivatives as anti-inflammatory agents for atopic dermatitis treatment by inhibiting JAK1/STAT3 signaling pathway.
SVCT2-targeted PET imaging agent for the evaluation of LN metastasis of thyroid cancer.
Melatonin treatment increases skin microbiota-derived propionic acid to alleviate atopic dermatitis.
circTUBD1-hnRNPK Regulates the Proliferation and Migration of LSCC by Targeting CCAR1.
USP5 Promotes Head and Neck Squamous Cell Carcinoma Progression via mTOR Signaling Pathway.
Melanoma Cell Adhesion Molecule Plays a Pivotal Role in Proliferation, Migration, Tumor Immune Microenvironment, and Immunotherapy in Colorectal Cancer.
Anti-colorectal cancer actions of Glycyrrhiza uralensis Fisch. and its underlying mechanism via HPLC integration and network pharmacological approaches.
Zn(2+) protects H9C2 cardiomyocytes by alleviating MAMs-associated apoptosis and calcium signaling dysregulation.
Mechanism underlying CDC20 affecting epithelial ovarian cancer biological behavior by regulating BAG6 ubiquitination.
SGK1 mediates herpes simplex keratitis via the PI3K/SGK1/ Wnt signaling pathways.
Circ-SPATA13 regulates the osteogenic differentiation of human periodontal ligament stem cells through the miR-485-5p_R + 1/BMP7 axis.
Photothermal-Responsive Soluble Microneedle Patches for Meibomian Gland Dysfunction Therapy.
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
BPDE induces ferroptosis in hippocampal neurons through ACSL3 suppression.
Efficacy and mechanism of the XPO1 inhibitor selinexor combined with decitabine in T-cell lymphoblastic lymphoma.
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Piezo1 promotes intervertebral disc degeneration through the Ca(2+)/F-actin/Yap signaling axis.
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML.
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Network pharmacology and in vivo study: Unraveling the therapeutic mechanisms of Panax ginseng in potentially treating ulcerative colitis.
Golgicide A induces pyroptosis of lung cancer stem cells by regulating dTGN formation via GOLPH3/MYO18A complex.
Role of Galactosylceramide Metabolism in Satellite Glial Cell Dysfunction and Neuron-Glia Interactions in Painful Diabetic Peripheral Neuropathy.
The Effects of Sika Deer Antler Peptides on 3T3-L1 Preadipocytes and C57BL/6 Mice via Activating AMPK Signaling and Gut Microbiota.
Dihydromyricetin Alleviated Acetaminophen-Induced Acute Kidney Injury via Nrf2-Dependent Anti-Oxidative and Anti-Inflammatory Effects.
The shared mechanism of barrier dysfunction in ulcerative colitis and Alzheimer's disease: DDIT4/IL1β neutrophil extracellular traps drive macrophages-mediated phagocytosis.
L-Arabinose Alleviates Functional Constipation in Mice by Regulating Gut Microbiota and Metabolites.
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF-κB/NLRP3 signaling pathway.
circ_0000389 inhibits intervertebral disc degeneration by targeting the miR-346/KLF7 axis.
Perfluorobutanoic acid: A short-chain perfluoroalkyl substance exhibiting estrogenic effects through the estrogen-related receptor γ pathways.
Reticulophagy promotes EMT-induced fibrosis in offspring's lung tissue after maternal exposure to carbon black nanoparticles during gestation by a m(5)C-dependent manner.
CD47 Contributes to the Proliferation of Breast Cancer.
Analysis and identification of mitochondria-related genes associated with age-related hearing loss.
The LncRNA lnc-POTEM-4:14 promotes HCC progression by interacting with FOXK1.
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
KLF5 enhances CXCL12 transcription in adipose-derived stem cells to promote endothelial progenitor cells neovascularization and accelerate diabetic wound healing.
The Non-Antibacterial Effects of Azithromycin and Other Macrolides on the Bronchial Epithelial Barrier and Cellular Differentiation.
α-Conotoxin TxIB Reversed Nicotine-Induced Locomotor Sensitization and Nicotine-Enhanced Dopaminergic Activity in Mice.
Isorhamnetin ameliorates hyperuricemia by regulating uric acid metabolism and alleviates renal inflammation through the PI3K/AKT/NF-κB signaling pathway.
Prognostic implications of alternative splicing events and key splicing factors in head and neck squamous cell carcinoma.
Baicalin, Amoxicillin, and Probenecid Provide Protection in Mice Against Glaesserella parasuis Challenge.
Arsenic enhances cervical cancer cell radiosensitivity by suppressing the DNA damage repair pathway.
Functionally conserved inner mitochondrial membrane proteins CCDC51 and Mdm33 demarcate a subset of fission events.
(64)Cu Radiolabeled PDGFRβ-Targeting Affibody for PET Imaging in Pancreatic Cancer.
Application of a CYP1B1-Targeted NIR Probe for Breast Cancer Diagnosis, Surgical Navigation, and CYP1B1-Associated Chemotherapy Resistance Monitoring.
Mechanistic Insights into Salvigenin for Glucocorticoid-Induced Femoral Head Osteonecrosis: A Network Pharmacology and Experimental Study.
Niacin Ester Derivative of Brefeldin A as a Potential Dual-Target Arf1/BMX Inhibitor for Bladder Cancer.
Neurotransmitter 5-HT Further Promotes LL-37-Induced Rosacea-like Inflammation Through HTR3A.
CSF3R-AS promotes hepatocellular carcinoma progression and sorafenib resistance through the CSF3R/JAK2/STAT3 positive feedback loop.
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
FASN promotes lipid metabolism and progression in colorectal cancer via the SP1/PLA2G4B axis.
Aggregation of the constitutively active K296E rhodopsin mutant contributes to retinal degeneration.
Targeted Degradation of Bromodomain-Containing Protein 4 Enabled by Reactive Oxygen Species-Activatable NanoPROTACs as an Efficient Strategy to Reverse Liver Fibrosis in Chronic Liver Injury.
Construction and evaluation of a prognostic model based on the expression of the metabolism-related signatures in patients with osteosarcoma.
IL-33/ST2 signalling promotes tumor growth by regulating polarization of alternatively activated macrophages.
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
A self-assembling peptide-based hydrogel containing NF-κB inhibitors and NGF for peripheral nerve injury repair.
Mechanism of action of Danlou tablets affecting MAFLD via KEAP1-mediated oxeiptosis.
Oxytocin-loaded hydrogel promotes cartilage regeneration and regulates microenvironment.
Reprogramming Macrophage Phenotype Using a Reactive Oxygen Species-Responsive Liposome Delivery System for Inflammation Microenvironment Remodeling and Osteoarthritis Treatment.
LincRNA-ASAO promotes dental pulp repair through interacting with PTBP1 to increase ALPL alternative splicing.
GPER1/ACACB are potential target genes associated with intracranial aneurysm and vascular endothelial cell senescence.
A KIF1C-CNBP motor-adaptor complex for trafficking mRNAs to cell protrusions.
Amniotic fluid-derived exosomal miR-146a-5p ameliorates preeclampsia phenotypes by inhibiting HIF-1α/FLT-1 expression.
XIAP promotes metastasis of bladder cancer cells by ubiquitylating YTHDC1.
Effect of Benzyl Isothiocyanate on Anaplastic Thyroid Cancer Evaluated by Network Pharmacology Combined with Experiments.
Berberine Exerts Neuroprotective Effects in Alzheimer's Disease by Switching Microglia M1/M2 Polarization Through PI3K-AKT Signaling.
Compositionally unique mitochondria in filopodia support cellular migration.
DMC-BH derivative DMC-GF inhibits the growth of glioma stem cells by targeting the TRIM33/SLC25A1/mitochondrial oxidative phosphorylation pathway.
Prognostic and immunological implications of protein kinases in gastric cancer: a focus on hub gene ABL2 and its impact on the polarization of M2 macrophages.
Rewired m6A methylation of promoter antisense RNAs in Alzheimer's disease regulates global gene transcription in the 3D nucleome.
ASPM mediates nuclear entrapment of FOXM1 via liquid-liquid phase separation to promote progression of hepatocarcinoma.
MDA5 protein mediating persistent ER stress/unfolded protein response contributes to endothelial-mesenchymal-transition of lung microvascular endothelial cell in dermatomyositis.
miR-378d suppresses gastric cancer metastasis by targeting METTL4 to inhibit epithelial-mesenchymal transition.
Downregulated Expression of miR-200c-3p in Plasma Exosome as a Potential Biomarker in Takayasu's Arteritis.
Radiotherapy-derived engineered stem cell exosomes improve anti-glioma immunotherapy by promoting the formation of tertiary lymphoid structure and improve the release of type I interferon.
Identification of RNA processing factor LSM5 as a new adverse biomarker in nasopharyngeal carcinoma.
The m6A reader HNRNPC is a key regulator in DSS-induced colitis by modulating macrophage phenotype.
Single-molecule m(6)A detection empowered by endogenous labeling unveils complexities across RNA isoforms.
Estrogen via GPER downregulated HIF-1a and MIF expression, attenuated cardiac arrhythmias, and myocardial inflammation during hypobaric hypoxia.
BMAL1 attenuates intervertebral disc degeneration by activating the SIRT1/PGC-1α pathway: evidence from vitro studies.
Precision Quantification and Rational Regulation of Protein Expression with Bicistronic Cassette for Efficient Biotin Production.
NEK2 promotes the progression of osteosarcoma through the AKT/p-AKT pathway and interacts with FoxM1.
FKBP51 is Involved in Epileptic Seizure by Regulating PSD95 in a PTZ-Induced Epileptic Mouse Model.
Chitosan Oligosaccharides Prevent Alcohol-Induced Liver Disease by Attenuating Inflammation and Oxidative Stress.
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer.
Oroxylin A reverses SHP-2 oxidative inactivation in GPVI signaling to suppress platelet activation and thrombus formation.
Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis.
Human umbilical cord mesenchymal stem cell-derived exosomes promote osteogenesis in glucocorticoid-induced osteoporosis through PI3K/AKT signaling pathway-mediated ferroptosis inhibition.
Trans-Golgi network tethering factors regulate TBK1 trafficking and promote the STING-IFN-I pathway.
S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis.
TRIM22 inhibits the metastasis of colorectal cancer through facilitating β-Catenin degradation.
MiR-222-3p loaded stem cell nanovesicles repair myocardial ischemia damage via inhibiting mitochondrial oxidative stress.
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation.
Noradrenaline Synergistically Enhances Porphyromonas gingivalis LPS and OMV-Induced Interleukin-1β Production in BV-2 Microglia Through Differential Mechanisms.
Engineered macrophage membrane-coated nanoparticles attenuate calcium oxalate nephrocalcinosis-induced kidney injury by reducing oxidative stress and pyroptosis.
Transmembrane protein 176B promotes epithelial-mesenchymal transition in colorectal cancer through inflammasome inhibition.
An advanced cytosine base editor enabled the generation of cattle with a stop codon in the β-lactoglobulin gene.
ERBB4 as a therapeutic target in aortic dissection: Implications for cell-based therapies in vascular regeneration.
Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo.
Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction.
Evaluation of anti-hyperuricemic and nephroprotective activities and discovery of new XOD inhibitors of Morus alba L. root bark.
Network pharmacology integrated with experimental validation reveals the mechanism of Xanthii Fructus against allergic rhinitis via JAK2/STAT3/HIF-1α signaling pathway.
Huachansu Injection induces ferroptosis in multiple myeloma through NRF2/HO-1 signaling pathway.
Inhibition of stemness and PD-L1 expression by Pien Tze Huang enhances T cell-mediated killing of colorectal cancer.
Identification of TAP2 as a novel immune target in human cancers: insights from integrated bioinformatics and experimental approaches.
Circ-AARS plays an important role during the odontogenic differentiation of dental pulp stem cells by modulating miR-24-3p/KLF6 expression.
Identification of ETFDH gene c. 487 + 2 T > A pathogenic variant and mechanisms for polycystic kidney in neonatal onset MADD.
LST1 expression correlates with immune infiltration and predicts poor prognosis in acute myeloid leukemia.
The feedback loop between miR-222-3p and ZEB1 harnesses metastasis in renal cell carcinoma.
Decoding CKD-induced muscle atrophy through the critical role of lncRNA GAS5 and pyroptosis.
Gengnianchun formula ameliorates insulin resistance-induced diminished ovarian reserve via the estrogen signaling pathway: evidence from network pharmacology and experimental validation.
HDAC11 in ovarian granulosa cells coordinates LH in the maturation of oocytes in Tan sheep.
Efficacy and mechanism of inhibition of the GPR30-PI3K pathway by 4-phenylbutyric acid in the treatment of intrahepatic cholestasis of pregnancy.
Magnetically triggered thermoelectric heterojunctions with an efficient magnetic-thermo-electric energy cascade conversion for synergistic cancer therapy.
Berberine-inspired ionizable lipid for self-structure stabilization and brain targeting delivery of nucleic acid therapeutics.
Mitochondria are positioned at dendritic branch induction sites, a process requiring rhotekin2 and syndapin I.
Protective effects of Rosa roxburghii Tratt. extract against UVB-induced inflammaging through inhibiting the IL-17 pathway.
The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision.
Manganese-Based Nanozyme Alleviates Acute Kidney Injury via Nrf2/HO-1 and PI3K/Akt/NF-κB Signaling Pathways.
GRASP55 regulates sorting and maturation of the lysosomal enzyme β-hexosaminidase A.
Bisphenol A exposure enhances proliferation and tumorigenesis of papillary thyroid carcinoma through ROS generation and activation of NOX4 signaling pathways.
Bisphenol F induces spermatogenic cell ferroptosis via FTO-mediated m6A regulation of FTH1.
Baicalin reduced vandetanib induced myocardial injury by regulating redox balance and NLRP3 inflammasome pathway.
HIF-3α Facilitates the Proliferation and Migration in Pancreatic Cancer by Inhibiting Autophagy Through Downregulating TP53INP2.
TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling.
Protein S-glutathionylation confers cellular resistance to ferroptosis induced by glutathione depletion.
Cth/Mpst double ablation results in early onset fatty liver disease in lean mice.
Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances.
Picroside II regulates the YY1/TGFβ1 axis by inhibiting osteoblast ferroptosis to alleviate symptoms of postmenopausal osteoporosis.
Catalpol inhibits Hedgehog signaling pathway to suppress proliferation and promote lipid accumulation in rat meibomian gland epithelial cells.
Fluoride induces hepatointestinal damage and vitamin B(2) mitigation by regulating IL-17A and Bifidobacterium in ileum.
ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment.
Olaparib Combined with Anti-PD1 Enhances Immunotherapy of Gastric Cancer Via NF-κB/c-Myc/PD-L1 Signaling.
TREML2 enhances sensitivity of acute myeloid leukemia cells to chemotherapy by inhibiting the NF-κB/CXCL10 pathway.
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
Linc00239 Facilitates the Progress of Clear Cell Renal Cell Carcinoma via the miR-204-5p/RAB22A Axis.
TSPAN31 Activates Fatty Acid Metabolism and PI3K/AKT Pathway to Promote Tumor Progression in Breast Cancer.
Identification and Validation of Basement Membrane Related LncRNA Signatures as a Novel Prognostic Model for Hepatocellular Carcinoma.
Knockdown TNF family prognosis index crucial gene PDE4B promoted PANoptosis of ovarian carcinoma cell:Based in vitro and in vivo experiments.
The phosphatase CTDSPL2 promotes proliferation, invasion, metastasis and regorafenib resistance in osteosarcoma.
Upregulation of YY1 in M2 macrophages promotes secretion of exosomes containing hsa-circ-0000326 via super-enhancers to facilitate prostate cancer progression.
Exogenous hydrogen sulfide improves non-alcoholic fatty liver disease by inhibiting endoplasmic reticulum stress/NLRP3 inflammasome pathway.
Functional Upregulation of TRPM3 Channels Contributes to Acute Pancreatitis-associated Pain and Inflammation.
ADAM10-mediated β-klotho degradation: a key to FGF21 resistance in senescent vascular endothelial cells.
Bardoxolone displays potent activity against triple negative breast cancer by inhibiting the TRIP13/STAT3 circuit.
Androgen Receptor Mediates Dopamine Agonist Resistance by Regulating Intracellular Reactive Oxygen Species in Prolactin-Secreting Pituitary Adenoma.
Identification of GABBR2 as a diagnostic marker and its association with Aβ in Alzheimer's disease.
The effects of FOXC2-gene-manipulated human periodontal ligament stem cells on bone regeneration of craniofacial bone defect.
S1PR2 Mediates Smooth Muscle Cell Proliferation and Endothelial Cell Permeability via Akt/mTOR and RhoA/ROCK1 in Atherosclerosis.
JNK kinase promotes inflammatory responses by inducing the expression of the inflammatory amplifier TREM1 during influenza a virus infection.
The role of LncRNA-MANCR induced by HIF-1α drive the malignant progression of pancreatic cancer by targeting miRNA-494/SIRT1 signaling axis under hypoxic conditions.
Decreased FTO Expression Promotes Ovarian Granulosa Cells Aging.
Hydrogel-mediated mitochondrial reprogramming for inducing cell death: a novel approach to overcoming gemcitabine resistance in pancreatic ductal adenocarcinoma.
A pH/MMP-9 smart dual-responsive liposome GBE@LP co-delivers and controls the release of GB1107/BMS1166/Enzalutamide for liver cancer immunotherapy.
Bufotalin loaded biomimetic nanodrug for combined chemo/photodynamic therapy of cancer.
Harnessing engineered exosomes as METTL3 carriers: Enhancing osteogenesis and suppressing lipogenesis in bone marrow mesenchymal stem cells for postmenopausal osteoporosis treatment.
Targeting m(6)A demethylase FTO to heal diabetic wounds with ROS-scavenging nanocolloidal hydrogels.
Sanghuangporus vaninii polysaccharides alleviates the effects of chlorpyrifos exposure on mouse liver: role of the gut- liver axis.
MicroRNA-9-3p inhibits endothelial pyroptosis in atherosclerosis by targeting the PTEN/AKT axis.
Enhancing BMSC chondrogenesis with a dynamic viscoelastic hyaluronan hydrogel loaded with kartogenin for cartilage repair.
miR-301a-5p regulated IKKβ/NF-κB axis and macrophage polarization to accelerate skin wound healing.
P4HB, a novel succinated protein, is essential for fumarate-induced cancer metastasis.
Sacituzumab tirumotecan in advanced non-small-cell lung cancer with or without EGFR mutations: phase 1/2 and phase 2 trials.
α‑ketoglutarate protects against septic cardiomyopathy by improving mitochondrial mitophagy and fission.
Role and mechanism of mitochondrial dysfunction‑related gene biomarkers in the progression of type 2 diabetes mellitus.
Human transmembrane protein 68 links triacylglycerol synthesis to membrane lipid homeostasis.
A potent dual inhibitor targeting COX-2 and HDAC of acute myeloid leukemia cells.
DPP7 Promotes Colorectal Cancer Progression Through GPX4-Dependent Suppression of Disulfidptosis and Immune Evasion.
LncRNA SNHG14 Regulated by ZNF460 Promotes Gastric Cancer Progression and Metastasis by Targeting the miR-206/FNDC3A Axis.
Effects of Adalimumab on Mitochondria of Psoriatic Mesenchymal Stem Cells.
Tripterygium wilfordii polyglycoside tablets attenuated the progression of hepatocellular carcinoma by targeting IL-6 and downstream signaling pathways in a multi-target manner.
Histone deacetylase 6 inhibition attenuates pathological cardiac hypertrophy by promoting autophagy through MAP1LC3B ubiquitination.
A Golgi apparatus-related signature predicts the immune microenvironment and prognosis of gastric cancer.
AMPK phosphorylation of K(Ca)2.3 alleviates angiotensin II-induced endothelial dysfunction.
TIMELESS as a prognostic biomarker and therapeutic target in gastric cancer.
Inhibition of SFRP1 by microRNA‑206‑3p may be the underlying cause of osteosarcopenia.
Targeting overexpressed HSPA8 by halofuginone suppresses aberrant proliferation and invasion of rheumatoid arthritis fibroblast-like synoviocytes.
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
Circovirus Rep evades immune restriction by disrupting cGAS oligomerization and phase separation.
The Erk1/2-EGR1 signaling pathway is involved in lipopolysaccharide-induced transforming growth factor-beta 1 expression in mouse macrophages.
Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition.
Angio-associated migratory cell protein promotes colorectal cancer progression by enhancing phosphoglycerate kinase 1 phosphorylation.
Rbm39 ameliorates metabolic dysfunction-associated steatotic liver disease by regulating Apob and Fabp4.
Aloe Vera flowers extracts inhibit melanogenesis via activating PI3K/Akt signaling pathway: Network pharmacology and experimental validation.
Anti-tumor effectiveness of a novel bispecific antibody that blocks both PD-L1 and LAG-3.
PLK1 Downregulation Attenuates ET-1-Induced Cardiomyocyte Hypertrophy by Suppressing the ERK1/2 Pathway.
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes.
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
MLKL‒OPTN axis regulates herpesvirus-induced neurological sequelae.
Pitavastatin-loaded procyanidins self-assembled nanoparticles alleviate advanced atherosclerosis via modulating macrophage efferocytosis and cholesterol efflux.
Kaempferol combats the osteogenic differentiation damage of periodontal ligament stem cells in periodontitis via regulating EphrinB2-mediated PI3K/Akt and P38 pathways.
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Tanshinone IIA promotes ferroptosis in cutaneous melanoma via STAT1-mediated upregulation of PTGS2 expression.
An Energy Metabolism Nanoblocker for Cutting Tumor Cell Respiration and Inhibiting Mitochondrial Hijacking from Cytotoxic T Lymphocyte.
Artificial intelligence-driven microRNA signature for early detection of gastric cancer: discovery and clinical functional exploration.
Study on the Mechanism of Fisetin Exerting Anti-Liver Cancer Effects by Regulating Neutrophil Extracellular Traps.
ULBP2 promotes progression of head and neck squamous cell carcinoma by modulating MAPK signaling pathway.
Long non-coding RNA ANRIL/p65 negative feedback loop protects intestinal barrier function in inflammatory bowel disease.
Ginsenoside Rg1 improves autophagy dysfunction to ameliorate Alzheimer's disease via targeting FGR proto-oncogene.
Triglyceride-lowering effect of rice protein due to the regulation of fatty acid uptake and transport of triglyceride in rats fed normal/oil-enriched diets.
Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H(2)O(2)-induced injury in PC12 cells.
OTUB1-SLC7A11 Axis Mediates 4-Octyl Itaconate Protection Against Acetaminophen-Induced Ferroptotic Liver Injury.
α9 Nicotinic Acetylcholine Receptor Promotes Tumor Proliferation and Suppresses Ferroptosis in Triple-Negative Breast Cancer.
Role and mechanism of lncRNA ZEB1-AS1 endogenous competition for miR-365a-3p targeting NRF2 in ferroptosis in articular chondrocytes.
An ultra-high-performance tandem mass spectrometry method to quantify tryptophan metabolites in aqueous humor of primary angle-closure glaucoma patients.
Acevaltrate overcomes myeloma resistance to bortezomib via pyroptosis by promoting BAX translocalization to mitochondria.
Mitochondrial oxidative stress inhibited Sirt3/Foxo3/PPARα pathway and aggravated copper and zinc co-deficiency-induced hepatic lipotoxicity in a fish model.
EHDPP impairs intestinal microbiota homeostasis and induces placental injury through choline mediated gut-placenta axis.
Exploring the immunomodulatory mechanism of total glucosides of paeony on Sjögren's syndrome dry eye disease based on the "gut-eye axis" pathway.
Dehydrodiisoeugenol targets NOD2 exerting dual effects against colitis and colorectal cancer: a double-edged sword.
Discovery of potent and selective CDK2 inhibitors with high safety and favorable bioavailability for the treatment of cancer.
Molecular adaptations in MMP genes support lung elasticity and diving adaptations in cetaceans.
β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1.
Inhibition of CTSC contributes to psoriasis inflammation and keratinocyte hyperproliferation by NF-κB signaling pathway.
TGF-β1 induces autophagy and mediates the effect on macrophages differentiation in primary liver cancer.
The JAK1/STAT3 pathway mediates the effects of SERPINH1 on glioma EMT.
FTY720 alleviates D-GalN/LPS-induced acute liver failure by regulating the JNK/MAPK pathway.
Ergosterol Protects Canine MDCK Cells from Gentamicin-Induced Damage by Modulating Autophagy and Apoptosis.
Atlas of lysine propionylation of human right atrium and ALDH6A1-NADH pathway in new-onset atrial fibrillation after coronary surgery.
Elucidation of Molecular Mechanisms of Sulfated Oligoguluronic Acid on Mitigating Intestinal Inflammation and Enhancing Epithelial Barrier Function.
Pro-Arrhythmic Effect of Chronic Stress-Associated Humoral Factors in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Nervonic acid mitigates IMQ-triggered psoriasis in mice via inhibiting Th17/γδT17 cell invasion and modulating the gut microbiota.
Alpha-1 antitrypsin modulates neutrophil phenotype and function: implications for inflammatory regulation.
Fibril fuzzy coat is important for α-synuclein pathological transmission activity.
NR5A1 Deficiency Leads to Decidualization Dysregulation of Stromal Cells and Recurrent Spontaneous Abortion During Early Pregnancy.
Characterization of T cell proliferation-associated hepatocellular carcinoma subtypes, predictive signatures, and candidate targets.
Theaflavin inhibits the malignant phenotype of human anaplastic thyroid cancer 8305C cells by regulating lipid metabolism via PI3K/AKT signaling.
Transcriptional regulation of solute carrier family 6 member 9 gene.
PSMB10 maintains the stemness of chemotherapeutic drug-resistant leukemia cells by inhibiting senescence and cytotoxic T lymphocyte-mediated killing in a ubiquitinated degradation manner.
PRMT1 inhibition enhances the cardioprotective effect of adipose-derived mesenchymal stem cells against myocardial infarction through RUNX1.
Tumor-intrinsic TTLL12 drives resistance to cancer immunotherapy via modulating myeloid-derived suppressor cells.
E3 ubiquitin-protein ligase CBL inhibits non-small cell lung cancer progression via ubiquitination and degradation of KDR.
Transcriptomic and Functional Validation Reveals PAQR3/P6-55 as Potential Therapeutic Targets in Colon Cancer.
Saroglitazar Ameliorates Pulmonary Fibrosis Progression in Mice by Suppressing NF-κB Activation and Attenuating Macrophage M1 Polarization.
Proteomics based discovery of Salvia miltiorrhiza Bunge treating Parkinson's disease through the PINK1/Parkin pathway.
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Reduced NRF2/Mfn2 activity promotes endoplasmic reticulum stress and senescence in adipose-derived mesenchymal stem cells in hypertrophic obese mice.
Inflammation-induced TET3/mir-3942 axis impedes the proliferation and invasion ability of trophoblast cells through destabilization of SERPINE1 in preeclampsia.
Integrated transcriptome analysis and combinatorial machine learning to construct a homeostatic model of acetylation for ccRCC and validate the key gene GCNT4.
Endoplasmic reticulum-anchored nonstructural proteins drive human astrovirus replication organelle formation.
Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders.
UBE3C promotes pancreatic ductal adenocarcinoma progression by catalysing p53 ubiquitination.
Bright-light treatment ameliorates motor and non-motor deficits through distinct visual circuits in a mouse model of Parkinson's disease.
ENPP1 governs the metabolic regulation of effector T cells in autoimmunity by detecting cytosolic mitochondrial DNA.
Expression Dynamics and Estrogen Response of Estrogen Receptors in Duolang Sheep During Puberty.
5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy activation.
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer.
Gut microbiota from voluntary exercised mice protects the intestinal barrier by inhibiting neutrophil extracellular trap formation.
Taurine ameliorates blood pressure and vascular function in patients with type 2 diabetes: Randomized, double-blind, placebo-controlled trial.
Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway.
UHRF1 phase separation mediates stable inheritance of DNA methylation and promotes the proliferation of prostate cancer cells.
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
DNA Damage Response Regulation Alleviates Neuroinflammation in a Mouse Model of α-Synucleinopathy.
Fatty Acid Desaturase 1 Knockdown Promotes Wound Healing and Functional Recovery of the Corneal Epithelium in Diabetes.
A Novel Modulator of Resistance for Oxaliplatin-Based Therapy for Colorectal Cancer: The ESCRT Family Member VPS4A.
Combination of Ginsenoside Compound K and Anti-PD1 Inhibits Pancreatic Cancer by Activating CXCL13-CXCR5 Signaling Axis.
Antrodia cinnamomea Extract Attenuates Obesity by Targeting Adipogenic Pathways and Gut Dysbiosis in High-Fat Diet-Fed Mice.
Spatiotemporal Circadian Oscillator Manipulation for Enhanced Ovarian Cancer Therapy Using a Versatile Nanoplatform.
Paracrine Action of Bone Morphogenetic Protein 3 in Pulmonary Arterial Hypertension.
The use of sialic acids as attachment factors is a common feature of Enterovirus-D species.
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes.
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Mechanical tension-induced Dalrd3 elevation enhances osteogenic differentiation of bone suture stem cells by upregulating Id3 translation.
Galectin-1: An important regulator in myeloid differentiation and acute myeloid leukemia as well as a promising prognostic indicator and therapeutic target.
Human neural stem cell-derived small extracellular vesicles enhance functional recovery after ischemic stroke through the miR-362-3p/MCAM/Wnt/β-catenin axis.
Halicin Reduces the Warburg Effect and Overcomes Drug Resistance by Activating the Pyruvate Kinase M2 Pathway for Triple-Negative Breast Cancer Treatment.
Calycosin treats acute myocardial infarction via NLRP3 inflammasome: Bioinformatics, network pharmacology and experimental validation.
NADPH oxidase 2 inhibitor GSK2795039 prevents against cardiac remodeling after MI through reducing oxidative stress and mitochondrial dysfunction.
Acetaldehyde dehydrogenase 2 attenuates lipopolysaccharide -induced endothelial barrier damage by inhibiting mitochondrial fission in sepsis-associated encephalopathy.
Carbon monoxide gas molecules: Therapeutic mechanisms in radiation-induced lung injury.
Protein Kinase D Knockdown Alleviates Vascular Calcification Through P53-SLC7A11 Axis-Mediated Ferroptosis.
Aspirin Suppresses Aromatase-Mediated Estrogen Biosynthesis to Alleviate Polycystic Ovary Syndrome by the Inhibition of Adenylate Cyclase.
METTL3 Modulates Radiation-Induced Cardiac Fibrosis via the Akt/mTOR Pathway.
HBV-induced N6 methyladenosine modification of PARP1 enhanced AFB1-related DNA damage and synergistically contribute to HCC.
Neurotransmitter imbalance and amygdala synaptic plasticity in lumbar disc herniation-induced chronic pain and related emotional Disturbances:A multi-omics analysis.
Red nucleus mGluR4 and mGluR8 inhibit nociception and the development of neuropathic pain by restraining the expressions of TNF-α and IL-1β.
Transcranial magnetic stimulation through attenuating blood-spinal cord barrier disruption and reducing inflammatory response to improve motor function in rats with spinal cord injury.
Genome-guided discovery of coublibactins from Nocardia coubleae and their gallium complexes with potent antileukemic activity.
A Single-Chain Variable Fragment Antibody Alleviates Inflammation and Apoptosis of Neurons by Inhibiting Tau Aggregation.
Generation and characterization of a DYNLT1-knockout mouse model reveals electrophysiological alterations and potential mechanistic contributors to atrial fibrillation.
Tumor-derived CXCL5 promotes 5-fluorouracil resistance in colorectal cancer cells via p21 downregulation.
KLF4 mediates the contradictory effects of phenylethyl isothiocyanate in gastric cancer intervention.
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Deciphering the polypharmacology of Dingzhi Xiaowan against comorbid depression: Integrated metabolomics of brain tissue and network pharmacology analysis in chronic restraint stress (CRS)-LPS model.
Qingfei Litan decoction alleviated Klebsiella pneumoniae-induced pneumonia by targeting the TLR4/MyD88/NF-κB axis via miR-146a-5p.
Integrator loss leads to dsRNA formation that triggers the integrated stress response.
Melatonin mitigates ovarian aging through regulation of the YTHDF2/m (6)A/UBE3C axis.
Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway.
Overexpression of miR-671-3p alleviates postmenopausal osteoporosis by targeting GREM2 to activate BMP2/SMAD signaling pathway.
tRF-22-WE8SPOX52 promotes progression of breast cancer by down-regulating MAP2K4.
Vinpocetine-mediated multidimensional active targeted delivery across the blood-brain barrier.
Bioengineered bacterial extracellular vesicles for targeted delivery of an osteoclastogenesis-inhibitory peptide to alleviate osteoporosis.
Novel mutation SLFN14 T853fs associated with inherited macrothrombocytopenia.
Hyperandrogen-induced imbalance of FOXO4-AR regulatory loop contributes to ovulatory disorders in polycystic ovary syndrome.
Lipidomics reveals biomarkers of the efficacy of first-line ICI therapy combined with chemotherapy in NSCLC.
Combined protein and transcriptomics identifies DCTPP1 as a putative biomarkers for predicting immunotherapy responsiveness in gastric cancer patients.
The PPARβ/CERK/C1P signaling pathway is a potential mechanism by which antimony exposure promotes prostate cancer cell proliferation.
Ambient fine particulate matter induces cardiac fibrosis through triggering ferroptosis by heme degradation induced-iron overload.
Spinal astrocyte-derived M-CSF mediates microglial reaction and drives visceral hypersensitivity following DSS-induced colitis.
Pharmacological inhibition of Kv1.3 channel reduces sevoflurane-induced cognitive impairment through NLRP3-dependent microglial modulation.
A novel MMP-9 inhibitor exhibits selective inhibition in non-small-cell lung cancer harboring EGFR T790M mutation by blocking EGFR/STAT3 signaling pathway.
Muscle-homing peptides modified biomimetic curcumin nanoparticles ameliorate skeletal muscle dysfunction in aging mice.
PINK1 Loss of Function Selectively Alters the Mitochondrial-Derived Vesicle Pathway.
Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition.
GDF11 Regulates M1 and M2 Polarization of BV2 Microglial Cells via p38 MAPK Signaling Pathway.
Pilot Exploration of RGMa-BMP4 Signaling in Neutrophil Activation in NMOSD: Integrating Clinical and Molecular Insights.
Inhibiting the REV-ERBα expression protects against mechanical overloading-induced cartilage clock disruption and osteoarthritis progression.
ω-3 PUFAs Alleviate GJ-Cx43 Uncoupling Induced by Long-Term Isoflurane Exposure by Activating the Wnt/β-catenin Signaling Pathway in Astrocytes.
GDF15 attenuates Parkinson's disease progression via suppressing the activation of cGAS-STING pathway.
PUS7 promotes the progression of pancreatic cancer by interacting ANLN to activate MYC pathway.
The role of mitochondrial dysfunction in the protective effect of ginger derived extracellular vesicles on hepatic stellate cells against cytotoxicity.
FNDC5/Irisin exacerbates APAP-induced acute liver injury through activating JNK/NF-κB and inflammatory response.
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy.
TP53INP2 promotes mitophagic degradation of YAP to impede dedifferentiated liposarcoma development.
Advanced N-glycoproteomics and proteomics approach revealed sexually dimorphic molecular signatures in primary mouse hepatocyte.
Tinosinenside A inhibits neuroinflammation and protects HT22 cells by suppressing the TLR4/NF-κB/NLRP3 signaling pathway in BV2 cells.
SPATA2/CYLD Pathway-Dependent Deubiquitylation of p53 Promotes Ferroptosis in Rat Heart After Ischaemia/Reperfusion Through Suppression of SLC7A11.
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Cataract-causing variant G119R impaired the oligomeric homeostasis of βB2-crystallin with lower structural stability and more sensitivity to the environmental stress.
HIV-1 Tat mediates microglial NLRP3 inflammasome activation and neurotoxicity by inducing cytosolic mtDNA stress.
Nano-pectic polysaccharide from vinegar-baked Radix Bupleuri enhances methotrexate efficacy against hepatocellular carcinoma via BCRP and MRP2 downregulation.
miR166u -enriched Polygonatum sibiricum exosome-like nanoparticles alleviate colitis by improving intestinal barrier through the TLR4/AKT pathway.
A high-performance chitosan-grafted Cu(Ⅱ) coating improves endothelialization and mitigates the degradation of biodegradable magnesium alloy stents.
FoxO4 reduces the damage and mechanism of PEDV-infected IPEC-J2 cells through the NF-κB/MLCK pathway.
Quantification profiles of enzyme activity, secretion, and psychosine levels of Krabbe disease galactosylceramidase missense variants.
Transthyretin, a novel prognostic marker of POCD revealed by time-series RNA-sequencing analysis.
Oxaliplatin accelerates immunogenic cell death by activating the cGAS/STING/TBK1/IRF5 pathway in gastric cancer.
Myeloid MyD88 Mediates Macrophage Infiltration and Activation in Ang II-Induced Cardiac Hypertrophy.
HBx Drives Liver Cancer Stem Cell Generation Through Stimulating Glucose Metabolic Reprogramming.
Exploration of the Potential Bioactive Compounds and Functional Mechanism of Chaihu Sanshen Capsule in Ameliorating Myocardial Ischaemia-Reperfusion Injury: A Serum Pharmaco-Chemistry With Network Pharmacology Analysis.
Identification of LDHA as a Potential Therapeutic Target for Pulmonary Hypertension Through Modulation of Endothelial-To-Mesenchymal Transition.
A Dendrobium chrysotoxum extract erianin induce AML cells death by activating PPARɑ and downregulating PI3K/AKT signaling pathways.
Scutellarein ameliorates pulmonary arterial hypertension via sirtuin 1 mediated deacetylation of nicotinamide nucleotide transhydrogenase.
Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis.
Discovery of a novel BCL-2 inhibitor GW806742X for the treatment of TNBC.
Pasteurized Akkermansia muciniphila ameliorates preeclampsia via inhibiting mitochondrial dysfunction-mediated placental apoptosis in vivo and in vitro.
Identification of cytochrome P450 2E1 as a novel target in neuroinflammation and development of its inhibitor Q11 as a treatment strategy.
High soluble expression and characterization of human GalNAc transferase T2 and T11 in Escherichia coli.
Cardiac Troponin I Promotes the Development of NSCLC Cells Through the Expression of Notch and Kras Proteins.
Activation of spinal PGC-1α regulates microglial polarization through a feedback loop between ROS-mediated mitochondrial dysfunction and the NLRP3 inflammasome in neuropathic pain.
Optineurin knock-out forms TDP-43 aggregates to regulate TDP-43 protein levels despite autophagic up-regulation and aberrant TDP-43 expression.
Unripe apple polyphenols extract improves intestinal inflammation and restructures gut microbiota in spontaneously hypertensive rats.
Sex-biased zinc responses modulate ribosomal protein expression, protein synthesis and social defects in Cttnbp2 mutant mice.
Glyphosate exposure impairs glucose and lipid metabolism by disturbing the circadian clock system in mice liver.
A-485 alleviates fibrosis and apoptosis in kidney by disrupting tandem activation of acetylation and phosphorylation on STAT3.
SLAMF9 aggravates myocardial ischemia reperfusion injury through activating the hippo-yap pathway.
Integrating LC-MS and molecular docking technology to investigate the effect of Spatholobi caulis flavonoids in alleviating primary dysmenorrhea via regulating the RhoA/ROCK pathway.
NRF2 modulates WNT signaling pathway to enhance photodynamic therapy resistance in oral leukoplakia.
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Disorder of phospholipid metabolism in the renal cortex and medulla contributes to acute tubular necrosis in mice after cantharidin exposure using integrative lipidomics and spatial metabolomics.
Oligomeric proanthocyanidin attenuates asthma severity and airway remodeling by modulating epithelial-smooth muscle cell interactions.
Ji-Ming-San enhances intestinal circadian rhythms and mitigates colitis in mice: The role of epithelial RORα.
Peiyuan Ningshen-ointment alleviates learning and memory impairment induced by sleep deprivation through activating the cAMP/PKA signaling pathway.
Medium-chain triglyceride attenuates obesity by activating brown adipose tissue via upregulating the AMPK signaling pathway.
HMGB1 Accelerates Wound Healing by Promoting the Differentiation of Epidermal Stem Cells via the "HMGB1-TLR4-Wnt/Notch" Axis.
Downregulation of miR-27a-3p induces endothelial injury and senescence and its significance in the development of coronary heart disease.
Polygonati Rhizoma Polysaccharides Ameliorated Diabetic Kidney Disease in db/db Mice via Inhibiting TGFβ/Smad2 Signaling Pathway.
Leucine-Rich Repeat Containing 15 Promotes the Inflammatory Response in Rheumatoid Arthritis by Regulating NF-κB Pathway.
Depalmitoylase ABHD16A negatively regulates the anti-hepatitis B virus activity of IFITM1.
C1q(+) Macrophage-Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma.
Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non-small Cell Lung Cancer.
Bovine collagen peptides and peptide-calcium complexes inhibit RANKL-induced osteoclast differentiation in RAW 264.7 macrophages.
Polysaccharides of Atractylodes macrocephala Koidz alleviate bursa of Fabricius involution in Magang geese by inhibiting the Wnt signaling pathway.
Protective effects of polysaccharide of Atractylodes macrocephala Koidz and Jiawei Si-jun-zi Decoction on gut health and immune function in cyclophosphamide-treated chicks.
UBC9 overexpression promotes proliferation and metastasis in gastric cancer via ATF2.
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Design, synthesis and anti-cancer activity of novel 1,2,3-triazole hybrids of erlotinib against cervical cancer via MAPK signaling pathway.
Akt isoform specificity drives intrinsic immune regulation during HSV-1 infection.
Leucine-rich repeat-containing protein 19 suppresses colorectal cancer by targeting cyclin-dependent kinase 6/E2F1 and remodeling the immune microenvironment.
Mechanism of Myh3 gene regulation of intramuscular fat content in Beijing black pigs via the MAPK signaling pathway.
Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling.
Cardiac-specific overexpression of PRMT5 exacerbates pressure overload-induced hypertrophy and heart failure.
Design, synthesis, and biological evaluation of quinolinyl-ureido-phenyl-hydrazide derivatives and quinolinyl-hydrazide derivatives as anticancer agents targeting Nur77-mediated ferroptosis.
Multi-omics analysis identifies SNP-associated immune-related signatures by integrating Mendelian randomization and machine learning in hepatocellular carcinoma.
Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway.
Nuclear receptor FXR inhibits ferroptosis to alleviate hepatic ischemia-reperfusion injury by targeting GPX4 in a mouse model.
Aggregation of the Constitutively Active K296E Rhodopsin Mutant Contributes to Retinal Degeneration.
LMOD2 interaction with ACTC1 regulates myogenic differentiation.
Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids.
Metabolic dysfunction promoted by mitochondrial DNA mutation burden drives retinal degeneration.
A Novel Field Resistance Mechanism: Two Structural Variations in FgOs1 Confer Ultrahigh Fludioxonil Resistance in Fusarium graminearum without Disrupting FgOs1 Transcription or Translation.
METTL3-mediated m (6)A modification facilitates Nectin-4-induced VNN1 upregulation and promotion of ESCC progression.
RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis.
Gypenosides Alleviate Hyperglycemia by Regulating Gut Microbiota Metabolites and Intestinal Permeability.
Influence of Gut Microbiota-Derived Butyrate on Intestinal Uric Acid Excretion and Hyperuricemia Regulation by Cichorium intybus L.
Pantothenic acid ameliorates hepatic fibrosis by targeting IGFBP6 to regulate the TGF-β/SMADs pathway.
Cold Stress Regulates Muscle Development and Promotes Muscle Fiber Transformation by Regulating Mib1/Notch Pathway.
Pilaralisib inhibits the replication of enteroviruses by targeting the PI3K/AKT signaling pathway.
Mefunidone treats pulmonary fibrosis by targeting SDH to regulate fibro-promoting macrophages.
Phytosterol-mediated disturbance of the lipid packing order in the plasma membrane regulates inflammatory response.
ShenQiGan Extract Repairs Intestinal Barrier in Weaning-Stressed Piglets by Modulating Inflammatory Factors, Immunoglobulins, and Short-Chain Fatty Acids.
Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a.
A designer polyQ fusion protein modulates NF-κB signaling by sequestering P65/RelA into aggregates.
Pulsed electromagnetic stimulation promotes neuronal maturation by up-regulating cholesterol biosynthesis.
Liraglutide attenuates autoimmune myocarditis by inhibiting NLRP3 and NF-κb pathways.
A missense mutation in TCFL5 is associated with male infertility due to oligoasthenoteratozoospermia.
Jianpi Huayu decoction enhances the antitumor effect of doxorubicin via piezo1-mediated autophagy in hepatocellular carcinoma.
Kirenol alleviates cerebral ischemic injury by promoting synaptic plasticity via HDAC2-mediated BDNF expression.
Discovery of TNI-97 as a Highly Selective, Orally Bioavailable HDAC6 Inhibitor for the Treatment of Triple-Negative Breast Cancer.
Sub-chronic realgar exposure causes liver inflammatory injury in mice by inducing bile acid-mediated NLRP3 inflammasome activation through down-regulation of ileal FXR.
Dahuang Huanglian Decoction alleviates dysbiosis by inhibiting GBP5/NLRP3 signaling pathway-mediated pyroptosis of colonic epithelial cells.
Integrating metabolomics and network pharmacology analysis provides new insights into the lipid metabolism disorder of Abrus mollis.
Exploring the mechanism of feiyanning formula and its extract apigenin against EGFR-TKIs resistance in non-small cell lung cancer based on UPLC-HRMS and experimental validation.
Renal tubular GSDME protects cisplatin nephrotoxicity by impeding OGT-STAT3-S100A7A axis in male mice.
Application of Mendelian randomization and bioinformatic analysis to construct a prognostic model for thyroid cancer and perform pan-cancer analysis.
Glucocorticoid-Induced Muscle Satellite Cell-Derived Extracellular Vesicles Mediate Skeletal Muscle Atrophy via the miR-335-5p/MAPK11/iNOS Pathway.
Single-cell RNA sequencing analysis revealed the immunosuppressive remodeling of tumor-associated macrophages mediated by the MIF-CD74 axis in gastric cancer.
Silver Needle Thermal Therapy Improves Mitochondrial Injury in the Skeletal Muscle of MPS Rats by Inhibiting the TRPV1/CaMKII Pathway.
Trigonelline attenuated sepsis-induced acute kidney injury by activating NAD+/SIRT1 Pathway.
Divergent Mechanisms of H2AZ.1 and H2AZ.2 in PRC1-Mediated H2A Ubiquitination.
Injectable thermosensitive hydrogel-encapsulated paclitaxel liposomes enriched with miR-455-3p antagomir for dormancy therapy of salivary adenoid cystic carcinoma.
MiR-1976 affects lung squamous cell carcinoma development by targeting NCAPH.
Heat shock protein 90 chaperone activity is required for hepatitis A virus replication.
Zika virus non-structural protein NS2A mediated endoplasmic reticulum stress through interacting with Sarco/endoplasmic reticulum Ca(2+)-ATPase 2.
TRIM56 enhances adenoviral E1A steady state to improve oncolytic adenovirus therapy efficacy.
Tyrosine kinase inhibitors induce cardiotoxicity by causing Ca(2+) overload through the inhibition of phosphoinositide 3-kinase activity.
TGF-β/snail-mediated epithelial-to-mesenchymal transition disrupts estradiol metabolism through suppressing the HSD17B2 expression in endometriotic epithelial cells.
Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastoma.
APG-115 Induces SLC7A11-Mediated Ferroptosis and Upregulates PD-L1 Expression in Thyroid Cancer.
Disruption of Acetyl-CoA Acyltransferase 2 Resulting from Exposure to Diosbulbin B.
C20orf27 promotes hepatocellular carcinoma progression via NT5E.
The p.W651fsX666 mutation on COL10A1 results in impaired trimerization of normal collagen X to induce Schmid type Metaphyseal chondrodysplasia.
Bio-engineered microRNA-7 effectively interferes with the Akt3/p53 axis to suppress human non-small cell lung cancer.
Antitumor effects of human antithymocyte globulin on peripheral T cell lymphoma via complement-dependent and -independent cytotoxicity in xenograft mouse models.
Mesenchymal Stem Cell Protection and Chondrogenic Differentiation in Tracheal Fistula Therapy via Bioactive Platinum Nanozymes.
Mitochondrial pyruvate carrier inhibits tumor growth by Bmi1 ubiquitination in renal cell carcinoma progression.
Integrated analyses to explore the mechanism of Gancao Renshen Zhixue Decoction in treating liver cirrhosis.
Exploring the molecular mechanisms of comorbidity between thyroid cancer and breast cancer through multi-omics data.
Identification and verification of oxidative stress-related genes in the diagnosis of osteoporosis.
CXCL12/CXCR4 modulates macrophage efferocytosis to induce glomerular crescent formation and fibrosis via ELMO1/DOCK180/RAC1 signaling in ANCA-associated glomerulonephritis.
Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer's disease-like pathology and cognitive decline.
NR4A1 Mediates Bronchopulmonary Dysplasia-Like Lung Injury Induced by Intrauterine Inflammation in Mouse Offspring.
Tryptophan-Rich Diet Improves High-Fat Diet-Induced Cognitive Dysfunction and Blood-Brain Barrier Disruption in C57BL/6 Mice through FFAR3 Activation.
Blocking or knockdown of P2X7 receptor inhibits invasion and migration of mouse breast cancer cells via PI3K/Akt/GSK-3β pathways and EMT.
Agrocybe cylindracea Polysaccharides Ameliorate DSS-Induced Colitis by Restoring Intestinal Barrier Function and Reprogramming Immune Homeostasis via the Gut-Liver Axis.
Chlorella pyrenoidosa Polysaccharide CPP-3a Promotes M1 Polarization of Macrophages via TLR4/2-MyD88-NF-κB/p38 MAPK Signaling Pathways.
Modeling oxaliplatin resistance in colorectal cancer reveals a SERPINE1-based gene signature (RESIST-M) and therapeutic strategies for pro-metastatic CMS4 subtype.
SOX4 promotes triple-negative breast cancer progression by promoting SRPX2 transcription to regulate AKR1C1.
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
LncRNA USP2-AS1 facilitates colorectal cancer development through the PHLDA2/PI3K/AKT axis.
Tumor-intrinsic ENO1 inhibition promotes antitumor immune response and facilitates the efficacy of anti-PD-L1 immunotherapy in bladder cancer.
Blocking calcium-MYC regulatory axis inhibits early dedifferentiation of chondrocytes and contributes to cartilage regeneration.
Exosomes derived from ALR-modified adipose mesenchymal stem cells mediate hepatoprotective effects on hepatic ischemia-reperfusion injury by promoting regeneration and protecting mitochondria.
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
The Antidiabetic Mechanisms of Cinnamon Extract: Insights from Network Pharmacology, Gut Microbiota, and Metabolites.
Near-infrared organic nanoparticles (6BQ NPs) enhance the random flaps survival by modulating the HSP90/HIF-1α axis through mild photothermal therapy.
Identification of hub six interferon alpha response genes and immune cell infiltration characteristics in low-grade glioma.
SPP1 promotes malignant characteristics and drug resistance in hepatocellular carcinoma by activating fatty acid metabolic pathway.
Chronic sleep deprivation induces plasma exosome-derived miR-150-5p downregulation as a novel mechanism involved in Parkinson's disease progression by targeting DCLK1.
Artesunate induces ferroptosis in diffuse large B-cell lymphoma cells by targeting PRDX1 and PRDX2.
TMEM150A overexpression was associated with poor prognosis and cancer progression in glioma verified by comprehensive analysis and cell experiments.
A Unique Amino Acid, Se-Met, Regulates Autophagy and Inflammation in Pseudomonas aeruginosa Infection in Mice through the PAK1/Akt1/mTOR and NF-κB Signaling Pathway.
Identification and analysis of extracellular matrix and epithelial-mesenchymal transition-related genes in idiopathic pulmonary fibrosis by bioinformatics analysis and experimental validation.
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
Transformable albumin-based nanocapsules selectively amplify tumor starvation and disulfidptosis through metabolic deception.
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.
Trim65 mitigates doxorubicin-induced myocardial injury by reducing ferroptosis.
Lipopolysaccharide amplifies the endocytosis of circulating exosomes derived from aortic dissection patients by the endothelial cells via a JMJD6 dependent manner.
THBS4 downregulation alters trophoblast function in preeclampsia via the TGF-β1/Smad signaling cascade.
Target inhibition of NAT10-mediated ac4C modification prevents seizure behavior in mice.
BAIAP2 as a driver of tumor progression in urothelial bladder cancer.
Platycodin D-mediated METTL16 downregulation promotes docetaxel treatment of prostate cancer by regulating ferroptosis.
Hsa_circ_0016662 acts as a prognostic biomarker and promotes the progression of hepatocellular carcinoma via autophagy regulation.
Phosphorylated IRF3 promotes GSDME-mediated pyroptosis through RIPK1/FADD/caspase-8 complex formation during mitotic arrest in ovarian cancer.
Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair.
Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions.
A Zinc-Citrate Metal-Organic Framework-Based Adaptable Hydrogen Sulfide Delivery System for Regulating Neuroregeneration Microenvironment in Spinal Cord Injury.
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1.
GFOD1 regulates oxidative stress-induced damage in ADHD via NF-κB signaling pathway.
A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.
In situ cryo-electron tomography reveals the progressive biogenesis of basal bodies and cilia in mouse ependymal cells.
Ultradeep N-glycoproteome atlas of mouse reveals spatiotemporal signatures of brain aging and neurodegenerative diseases.
AGGF1-primed endothelial progenitor cells alleviate ischaemia-reperfusion injury in diabetic hearts.
Lactylation associated biomarkers and immune infiltration in aortic dissection.
Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis.
Pan-cancer analysis of oncogenic role of MAGOH and experiment validation in hepatocellular carcinoma.
Effects of Paeoniae Radix Rubra on lowering lipid via bioinformatics and gut microbiome.
Ferroptosis is involved in the IL-9-induced intestinal barrier injury in sepsis: an experimental animal and translational study.
Circular RNA circLIMK1-005 promotes the progression of lung adenocarcinoma by interacting with RPA1 protein to activate CDK4 signaling.
Serum Pharmacology Combined with Network Pharmacology Reveals the Effects and Mechanisms of Ganmai Dazao Decoction in the Treatment of Depression.
IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders.
CBX3 Downregulates HLTF to Activate PI3K/AKT Signaling Promoting Cholangiocarcinoma.
The N-terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism.
USP21 stabilizes immune checkpoint of CD276 and serves as an immunological and tumor prognostic biomarker.
Network pharmacology, molecular docking, and experimental verification to reveal the mechanism of colquhounia root tablet in the treatment of diabetic nephropathy.
Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis.
In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor.
Human HDAC6 senses valine abundancy to regulate DNA damage.
Knockdown of DJ-1 Exacerbates Neuron Apoptosis Induced by TgCtwh3 through the NF-κB Pathway.
Mechanism Analysis of Selenium-Containing Compounds in Alleviating Spinal Cord Injury Based on Network Pharmacology and Molecular Docking Technology.
H1N1 swine influenza viruses upregulate NEU1 expression through histone H3 acetylation regulated by HDAC2.
27-Hydroxycholesterol contributes to hypercholesterolemia-associated aggravation of apical periodontitis in ovariectomized rats and raloxifene counteracts its action.
Dapagliflozin restores autophagy and attenuates apoptosis via the AMPK/mTOR pathway in diabetic nephropathy rats and high glucose-induced HK-2 cells.
KDM2A and KDM2B protect a subset of CpG islands from DNA methylation.
m6A methyltransferase METTL3 promotes non-small-cell lung carcinoma progression by inhibiting the RIG-I-MAVS innate immune pathway.
Niraparib perturbs autophagosome-lysosome fusion in pancreatic ductal adenocarcinoma and exhibits anticancer potential against gemcitabine-resistant PDAC.
Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.
Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma.
P21-activated kinase-1 signaling is required to preserve adipose tissue homeostasis and cardiac function.
Spermidine Recovers the Autophagy Defects Underlying the Pathophysiology of Cell Trafficking Disorders.
Esculetin facilitates post-stroke rehabilitation by inhibiting CKLF1-mediated neutrophil infiltration.
Downregulated YTHDF2 expression in systemic lupus erythematosus is associated with inflammatory and neutrophil cytokine production.
CARD11-BCL10-MALT1 Complex-Dependent MALT1 Activation Facilitates Myocardial Oxidative Stress in Doxorubicin-Treated Mice via Enhancing k48-Linked Ubiquitination of Nrf2.
ARC protects cochlear hair cells from neomycin-induced ototoxicity via the Ras/JNK signaling pathway.
Maternal Bisphenol A Exposure Induces Hippocampal-Dependent Learning and Memory Deficits Through the PI3K/Akt/mTOR Pathway in Male Offspring Rats.
Impact of an extended light regimen imposed during nursery period on the performance and lipid metabolism of weanling pigs.
Electroacupuncture Pretreatment Reduces Ischemic Brain Injury by Inhibiting the Lactate Production and Its Derived Protein Lactylation Formation.
SLC7A5 regulates tryptophan uptake and PD‑L1 expression levels via the kynurenine pathway in ovarian cancer.
Acute heat stress regulates estradiol synthesis in ovine ovarian granulosa cells through the SREBPs/MVK-LHR pathway.
Cetirizine platinum(IV) complexes with antihistamine properties inhibit tumor metastasis by suppressing angiogenesis and boosting immunity.
Effect of calcium concentration on metastasis of hepatocellular carcinoma cells cultured in alginate gel beads.
CaMKIIα-TARPγ8 signaling mediates hippocampal synaptic impairment in aging.
Co-exposure to Environmentally Relevant Levels of Molybdenum and Cadmium Induces Oxidative Stress and Ferroptosis in the Ovary of Ducks.
Integrin α2β1 deficiency enhances osteogenesis via BMP-2 signaling for accelerated fracture repair.
PIEZO1 mediates matrix stiffness-induced tumor progression in kidney renal clear cell carcinoma by activating the Ca(2+)/Calpain/YAP pathway.
De novo interleukin-10 production primed by Lactobacillus sakei CVL-001 amplifies the immunomodulatory abilities of mesenchymal stem cells to alleviate colitis.
The important role of the Wnt/β-catenin signaling pathway in small molecules mediated gingival mesenchymal stem cells transdifferentiate into neuron-like cells.
Melanoma-inhibiting activity promotes the migration and odontoblastic differentiation of stem cells of apical papilla.
Hepatocyte nuclear factor 4α as a sensitive marker for uterine endocervical adenocarcinomas and their precursors.
Wenshen Yiqi Granule Alleviates Chronic Obstructive Pulmonary Disease via the Long Noncoding RNA-XIST/MicroRNA-200c-3p Axis.
Targeting of retrovirus-derived Rtl8a/8b causes late-onset obesity, reduced social response and increased apathy-like behaviour.
Disruption of Ferroptosis Inhibition and Immune Evasion with Tumor-Activatable Prodrug for Boosted Photodynamic/Chemotherapy Eradication of Drug-Resistant Tumors.
Downregulation of cardiac inflammation via the CaMKII δ/NF-κB pathway in heart failure by Lonicerae Japonicae Flos and Angelicae Sinensis Radix.
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Multi-omics analysis reveals the protective effects of Chinese yam polysaccharide against cisplatin-induced renal interstitial fibrosis.
Echinacoside attenuates Klebsiella pneumoniae-induced pneumonia via inhibition of the TLR4/NF-κB signaling.
Psoralen and Isopsoralen Activate Nuclear Factor Erythroid 2-Related Factor 2 Through Interaction With Kelch-Like ECH-Associated Protein 1.
C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade.
Vericiguat enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction through microRNA-1180-3p/ETS1 pathway.
CXCL1-CXCR2 signaling mediates the activation of microglia in the nucleus tractus solitarii to promote pancreatic cancer-induced pain.
Cytoskeletal Vimentin Directs Cell-Cell Transmission of Hepatitis C Virus.
Harnessing Tumor Cell-Derived Exosomes for Immune Rejection Management in Corneal Transplantation.
Bioactive Self-Assembled Nanoregulator Enhances Hematoma Resolution and Inhibits Neuroinflammation in the Treatment of Intracerebral Hemorrhage.
MCM3 promotes hepatocellular carcinoma progression via Epithelial-mesenchymal Transition through AKT/Twist signaling pathway.
Long non-coding RNA LINC01224 plays an oncogenic role in endometrial cancer via miR-4673/TPX2 axis and activating Wnt/β-catenin signaling pathway.
Administration of β-Nicotinamide Mononucleotide Attenuates Myocardial Dysfunction in Tail-Suspended Mice.
Znhit1 alleviates nitroglycerin-induced hyperalgesia in migraine mice via the inhibition of NOD-like receptor signaling pathway.
The peripheral PI3K/AKT/MLC signalling pathway alleviates myofascial pain in rats by inhibiting abnormal contraction at myofascial trigger points.
Targeting sphingosine-1-phosphate receptor 1 alleviates neuropathic pain associated with pancreatic ductal adenocarcinoma in mice and inhibits tumor progression.
Transplantation of engineered endothelial progenitor cells with H19 overexpression promotes arterial reendothelialization and inhibits neointimal hyperplasia.
Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis.
circ_0075048 silencing regulates LCP1 to improve IL-1β-induced chondrocyte injury by binding with miR-663b.
5-(3-(N-(Carboxymethyl)naphthalene-2-sulfonamido)phenyl)-1-ethyl-1H-pyrrole-2-carboxylic acid as a Keap1-Nrf2 inhibitor for cerebral ischemia/reperfusion injury treatment.
A novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA.
The Effect of Adipose-Derived Stem Cell (ADSC)-Exos on the Healing of Autologous Skin Grafts in Miniature Pigs.
CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma.
hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p.
Inhibition of Endothelial-Mesenchymal Transition Mediated by Activin Receptor Type IIA Attenuates Valvular Injury Induced by Group A Streptococcus in Lewis Rats.
Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13.
Helicobacter pylori infection promotes M1 macrophage polarization and gastric inflammation by activation of NLRP3 inflammasome via TNF/TNFR1 axis.
Human DBR1 deficiency impairs stress granule-dependent PKR antiviral immunity.
Estrogen sulfotransferase SULT1E1 expression correlates with progression and prognosis of lung adenocarcinoma.
The effects of moderate alcohol and THC co-use during male and female rat adolescence on AKT-GSK3ß signaling in adulthood.
Exercise alleviates CUS-induced depressive-like behaviors by modulating paracellular and transcellular permeability of the blood-brain barrier in the prefrontal cortex.
Glycerophospholipid metabolic disorders and gender difference of cantharidin-induced hepatotoxicity in rats: Lipidomics and MALDI mass spectrometry imaging analysis.
Aristolochic acid I induced mitochondrial Ca(2+) accumulation triggers the production of MitoROS and activates Src/FAK pathway in hepatocellular carcinoma cells.
D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint.
Potassium molybdate blocks APN-dependent coronavirus entry by degrading receptor via PIK3C3-mediated autophagy.
Identification of viral protease-dependent cleavage sites within the human astrovirus polyprotein.
Swine RNF5 positively regulates the antiviral activity of IFITM1 by mediating the degradation of ABHD16A.
Tannic acid reactivates HIV-1 latency by mediating CBX4 degradation.
Remimazolam alleviates sleep deprivation induced anxiety-like behaviors via regulating the STING pathway.
The mechanism of exosomes of BMSCs modified with Bu Shen Yi Sui capsule in promoting remyelination via regulating miR-15b/Wnt signaling pathway-mediated differentiation of oligodendrocytes.
Centipeda minima extracts and the active sesquiterpene lactones have therapeutic efficacy in non-small cell lung cancer by suppressing Skp2/p27 signaling pathway.
Lichong decoction improves inflammatory microenvironment and alleviates fibrosis in uterine leiomyoma via targeting CXCL8.
Molecular insights into the therapeutic mechanisms of Bushen-Qiangdu-Zhilv decoction for ankylosing spondylitis.
Integrating metabolomics and network pharmacology to investigate Da-Chai-Hu Decoction prevents kidney injury in diabetic mice.
Baricitinib represses the myocardial fibrosis via blocking JAK/STAT and TGF-β1 pathways in vivo and in vitro.
Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization.
Taxus chinensis (Pilg.) Rehder fruit attenuates aging behaviors and neuroinflammation by inhibiting microglia activation via TLR4/NF-κB/NLRP3 pathway.
Exploring the liver toxicity mechanism of Tripterygium wilfordii extract based on metabolomics, network pharmacological analysis and experimental validation.
Simiao Wan attenuates high-fat diet-induced hyperlipidemia in mice by modulating the gut microbiota-bile acid axis.
Comparison of chemical composition between imitation wild and transplanted Astragali Radix and their therapeutic effects on heart failure.
Extract of Tinospora sinensis alleviates LPS-induced neuroinflammation in mice by regulating TLR4/NF-κB/NLRP3 signaling pathway.
Huang-Lian-Jie-Du Decoction alleviates diabetic encephalopathy by regulating inflammation and pyroptosis via suppression of AGEs/RAGE/NF-κB pathways.
Zangsiwei prevents particulate matter-induced lung inflammation and fibrosis by inhibiting the TGF-β/SMAD pathway.
Dehydrocorydaline attenuates myocardial ischemia-reperfusion injury via the FoXO signalling pathway: A multimodal study based on network pharmacology, molecular docking, and experimental study.
Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation.
Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway.
Dual efficacy of tocilizumab in managing PD-1 inhibitors-induced myocardial inflammatory injury and suppressing tumor growth with PD-1 inhibitors: a preclinical study.
Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway.
Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway.
Atractylenolide-III restrains cardiac fibrosis after myocardial infarction via suppression of the RhoA/ROCK1 and ERK1/2 pathway.
Deletion of BRCC3 ameliorates airway inflammation in asthma by inhibiting the activation of NLRP3 inflammasome.
6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy.
Enhanced Chondrogenic Potential and Osteoarthritis Treatment Using Cyaonoside A-Induced MSC Delivered via a Hyaluronic Acid-Based Hydrogel System.
Altered mitochondrial unfolded protein response and FGF21 secretion in MASLD progression and the effect of exercise intervention.
A Y178C rhodopsin mutation causes aggregation and comparatively severe retinal degeneration.
Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway.
LncRNA-ANRIL regulates CDKN2A to promote malignant proliferation of Kasumi-1 cells.
Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition.
Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome.
Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway.
Essential oils from Amorpha fruticosa against hepatocellular carcinoma based on network pharmacology.
DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway.
Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD.
An oral vaccine based on the Ad5 vector with a double-stranded RNA adjuvant protects mice against respiratory syncytial virus.
Mechanism of S100A9-mediated astrocyte activation via TLR4/NF-κB in Parkinson's disease.
STEAP3-SLC39A8-mediated microglia ferroptosis involved in neurotoxicity in rats after exposure to lead and cadmium combined.
Dihydromyricetin ameliorates neurotoxicity induced by high glucose through restraining ferroptosis by inhibiting JNK-inflammation pathway in HT22 cells.
Targeting hyperactive mitochondria in activated HSCs and inhibition of liver fibrogenesis in mice using sorafenib complex micelles.
Ubiquitin-conjugating enzyme E2T confers chemoresistance of colorectal cancer by enhancing the signal propagation of Wnt/β-catenin pathway in an ERK-dependent manner.
Retinol-Binding Protein 4 as a Biomarker in Cancer: Insights from a Pan-Cancer Analysis of Expression, Immune Infiltration, and Methylation.
The role of cGAS-STING pathway in the development of radiation-induced lung injury.
IDO1 inhibits ferroptosis by regulating FTO-mediated m6A methylation and SLC7A11 mRNA stability during glioblastoma progression.
Manganese exposure induces parkinsonism-like symptoms by Serpina3n-TFEB-v/p-ATPase signaling mediated lysosomal dysfunction.
Development of Sheep Intestinal Organoids for Studying Deoxynivalenol-Induced Toxicity.
YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies.
MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma.
Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining.
YTH N(6)-methyladenosine RNA Binding Protein 1 Inhibits Smooth Muscle Cell Phenotypic Modulation and Neointimal Hyperplasia.
Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis.
1-methyl-tryptophan improves anxiety-like behavior in colitis mice by inhibiting neuroinflammation, promoting cell regeneration, and decreasing apoptosis.
Docosahexaenoic acid mitigates experimental autoimmune prostatitis by inhibiting Th17 cell differentiation via the PPARγ/NF-κB/IL-17A pathway.
PKM2-mediated collagen XVII expression is critical for wound repair.
Maternal exposure to fullerenols impairs placental development in mice by inhibiting estriol synthesis and reducing ERα.
Peroxiredoxin 6 maintains mitochondrial homeostasis and promotes tumor progression through ROS/JNK/p38 MAPK signaling pathway in multiple myeloma.
Lidocaine Enhanced Antitumor Efficacy and Relieved Chemotherapy-Induced Hyperalgesia in Mice with Metastatic Gastric Cancer.
Both 20S and 19S proteasome components are essential for meiosis in male mice.
piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1.
Oxymatrine relieves non-alcoholic fatty liver disease by promoting sirtuin 1/adenosine 5'-monophosphate-activated protein kinase pathway and peroxisome proliferator activated receptor alpha-mediated hepatic fatty acid oxidation.
FHOD3 shows clinical significance in progression of ovarian cancer through regulation of caspase-3 signaling pathway.
TESC overexpression mitigates amyloid-β-induced hippocampal atrophy and memory decline.
Umbilical cord mesenchymal stem cell-derived exosomal Follistatin inhibits fibrosis and promotes muscle regeneration in mice by influencing Smad2 and AKT signaling.
Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc(-)/GSH/GPX4 axis.
Discovery of a potent anticancer agent against pancreatic ductal adenocarcinoma targeting FAK with DFG-out state and JAK/Aurora kinases.
Exploring the potential anti-COPD ingredients and mechanisms of the Qingfei decoction based on UHPLC-HRMS, network pharmacology and transcriptomic analysis.
Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention.
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Butyrate attenuates high-fat diet-induced glomerulopathy through GPR43-Sirt3 pathway.
Mechanism of Buyang Huanwu Decoction mediating Cav1-regulated Wnt pathway to promote neural regeneration in cerebral ischemic mice.
Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC.
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Developmental exposure to perfluorooctane sulfonate(PFOS) impairs the endometrial receptivity.
Gestational exposure to carbon black nanoparticles triggered fetal growth restriction in mice: The mediation of inactivating autophagy-lysosomal degradation system in placental ferroptosis.
Hyperactivity of the IL-33-ILC2s-IL-13-M-MDSCs axis promotes cervical cancer progression.
Lovastatin-mediated pharmacological inhibition of Formin protein DIAPH1 suppresses tumor immune escape and boosts immunotherapy response.
RNA m(6)A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells.
Restrictor slows early transcription elongation to render RNA polymerase II susceptible to termination at non-coding RNA loci.
Synergistic effects of combined lead and iprodione exposure on P53 signaling-mediated hepatotoxicity, enterotoxicity and transgenerational toxicity in zebrafish.
Tryptophan Metabolites Improve Intestinal Mucosal Barrier via the Aryl Hydrocarbon Receptor-Interleukin-22 Pathway in Murine Dextran Sulfate Sodium-Induced Pouchitis.
Puerarin reduces diabetic nephropathy-induced podocyte pyroptosis by modulating the SIRT1/NLRP3/caspase-1 pathway.
COPS5 regulates osteosarcoma progression by upregulating KHSRP to promote Per2 mRNA decay.
Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R.
Alterations in the transcriptome and microRNAs of adipose-derived mesenchymal stem cells from different sites in rats during aging.
Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring.
Hippocampal SENP3 mediates chronic stress-induced depression-like behaviors by impairing the CREB-BDNF signaling.
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Downregulation of LncRNA CCAT1 Enhances Chemosensitivity in Cisplatin-Resistant Gastric Cancer Cells.
High expression of ARPC1B promotes the proliferation and apoptosis of clear cell renal cell carcinoma cells, leading to a poor prognosis.
Lactamase β reprograms lipid metabolism to inhibit the progression of endometrial cancer through attenuating MDM2-mediated p53 ubiquitination and degradation.
Smooth Muscle Cell-Specific LKB1 Protects Against Sugen 5416/Hypoxia-induced Pulmonary Hypertension through Inhibition of BMP4.
NCAPD3-mediated AKT activation regulates prostate cancer progression.
Proline exacerbates hepatic gluconeogenesis via paraspeckle-dependent mRNA retention.
RGS22 maintains the physiological function of ependymal cells to prevent hydrocephalus.
A near-infrared triggered multi-functional indocyanine green nanocomposite with NO gas release function inducing improved photothermal therapy.
Integrin β4 Regulates Cell Migration of Lung Adenocarcinoma Through FAK Signaling.
LGR4 promotes proliferation and homing via activation of the NF‑κB signaling pathway in multiple myeloma.
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Antiviral mechanism of Fuzhengjiedu San against porcine reproductive and respiratory syndrome virus.
In vivo inhibition of CYP2E1 fails to reduce pulegone-induced liver injury in mice.
AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane.
Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma.
Trimethylamine N-oxide induces pyroptosis in HTR8-S/Vneo cells through the ten-eleven translocation 2-cytochrome b-reactive oxygen species pathway.
MARCHF1 promotes breast cancer through accelerating REST ubiquitylation and following TFAM transcription.
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway.
Low-dose SAHA enhances CD8(+) T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer.
Hypoxia inducible factor-1α promotes non-small cell lung cancer progression by activating leptin receptor transcription.
The Chinese Herbal Medicine Li Qi Huo Xue Di Wan Ameliorates Ischemia or Hypoxia-Induced Cardiac Injury and Remodeling in the Heart Through a Mechanism Involving Reduction of Necroptosis.
PB2 627V and HA 217 sites synergistically affect the lethality of H9N2 in mice.
Ginsenoside Rb prevents the metastasis of hepatocarcinoma by blocking the platelet-tumor cell interaction.
The Purinergic Ligand-Gated Ion Channel 7 Receptor Promotes the Proliferation, Invasion, and Migration of Breast Cancer Cells.
NUC7738 Induces Apoptosis Through Modulating Stability of P53 in Esophageal Cancer Cells.
Has_circ_ASH1L acts as a sponge for miR-1254 to promote the malignant progression of cervical cancer by targeting CD36.
H(2)S Donor SPRC Ameliorates Ischemic Stroke by Upregulating CD24.
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
SND1-SMARCA5 interaction strengthened by PIM promotes the proliferation, metastasis, and chemoresistance of esophageal squamous cell carcinoma.
Oxidative potential determines the oxidative stress and ferroptotic toxicity of airborne particulate matter on pulmonary epithelial cells.
Progranulin Protects Against Osteoporosis by Regulating Osteoclast and Osteoblast Balance via TNFR Pathway.
Antitumor effects of plasma‑activated solution on a murine melanoma model in vivo and in vitro.
Spinal pituitary adenylate cyclase-activating polypeptide and PAC1 receptor signaling system is involved in the oxaliplatin-induced acute cold allodynia in mice.
Aβ -induced excessive mitochondrial fission drives type H blood vessels injury to aggravate bone loss in APP/PS1 mice with Alzheimer's diseases.
CMAP prediction and experimental validation of Forskolin as a podocyte protective and anti-proteinuric drug for nephrotoxic serum-treated mice.
Hyperlipidemia impairs bone repair and regeneration via miR-193a-3p/STMN1/PI3K/Akt axis.
PTX3 impairs granulosa cell function by promoting the secretion of inflammatory cytokines in M1 macrophages via the JAK pathway.
Elucidating loss-of-function mechanisms of monoallelic EPAS1 mutations underlying congenital hypoplastic anaemia in a paediatric anaemia cohort.
Long-term effects of Nε-carboxymethyllysine intake on intestinal barrier permeability: Associations with gut microbiota and bile acids.
VNS facilitates the neurological function recovery after ischemia/reperfusion injury by regulating the A1/A2 polarization of astrocytes through the NMU-NMUR2 pathway.
5'tiRNA-33-CysACA-1 promotes septic cardiomyopathy by targeting PGC-1α-mediated mitochondrial biogenesis.
A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway.
Yiqi Huayu Jiedu formula inhibits JAK2/STAT3-mediated partial EMT in treating chronic atrophic gastritis.
Specific Monitoring the DNA Helicase Function via Anchor-Embedded DNA Probe.
Gut Commensal Barnesiella Intestinihominis Ameliorates Hyperglycemia and Liver Metabolic Disorders.
Cis-Regulation of an m(6)A Eraser by an Insertion Variant Associated with Survival of Patients With Non-Small Cell Lung Carcinoma.
D30 Alleviates β2-Microglobulin-Facilitated Neurotoxic Microglial Responses in Isoflurane/Surgery-Induced Cognitive Dysfunction in Aged Mice.
Exploring the Anti-Colorectal Cancer Mechanism of Norcantharidin Through TRAF5/NF-κB Pathway Regulation and Folate-Targeted Liposomal Delivery.
PRMT1-mediated methylation regulates MLL2 stability and gene expression.
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
STEAP3 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by Regulating Fatty Acid and Lipid Droplet Synthesis.
Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma.
Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia.
Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury.
NRG1-ErbB4 signaling in the cerebrospinal fluid-contacting nucleus regulates thermal pain in mice.
GATA3-Driven ceRNA Network in Lung Adenocarcinoma Bone Metastasis Progression and Therapeutic Implications.
Elevating VAPB-PTPIP51 integration repairs damaged mitochondria-associated endoplasmic reticulum membranes and inhibits lung fibroblasts activation.
Ferristatin II protects nucleus pulposus against degeneration through inhibiting ferroptosis and activating HIF-1α pathway mediated mitophagy.
Blockade of neddylation through targeted inhibition of DCN1 alleviates renal fibrosis.
Bi-allelic KICS2 mutations impair KICSTOR complex-mediated mTORC1 regulation, causing intellectual disability and epilepsy.
Comparative mitochondrial proteomic: PGAM5-mediated necroptosis through excessive mitophagy in sheep livers under molybdenum and cadmium co-exposure.
Tissue accumulation and hepatotoxicity of 8:2 chlorinated polyfluoroalkyl ether sulfonate: A multi-omics analysis deciphering hepatic amino acid metabolic dysregulation in mice.
Synthesis of novel deuterated EGFR/ALK dual-target inhibitors and their activity against non-small cell lung cancer.
Bispecific Aptamer-Drug Conjugates Selectively Eliminate Malignant Hematologic Cells for Treating Acute Myeloid Leukemia.
Integrative bioinformatics and experimental analyses identify U2SURP as a novel lactylation-related prognostic signature in esophageal carcinoma.
Implantable Polymer Scaffolds Loaded with Paclitaxel-Cyclodextrin Complexes for Post-Breast Cancer Tissue Reconstruction.
FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung adenocarcinoma.
Liver ALKBH5 regulates glucose and lipid homeostasis independently through GCGR and mTORC1 signaling.
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
The Regulatory Role of CircAGGF1 in Myogenic Differentiation and Skeletal Muscle Development.
A novel necroptosis-related miRNA signature for predicting the prognosis of esophageal cancer and immune infiltration analysis.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Deubiquitination enzyme USP35 negatively regulates MAVS signaling to inhibit anti-tumor immunity.
Identification of ETV4 as a prognostic biomarker and correlates with immune cell infiltration in head and neck squamous cell carcinoma.
LOX(+) iCAFs in HNSCC have the potential to predict prognosis and immunotherapy responses revealed by single cell RNA sequencing analysis.
The long noncoding RNA LUCAT1 regulates endometrial receptivity via the miR-495-3p/S100P axis.
Effects of simulated microgravity on dental pulp stem cell stemness.
Comparative Analysis of Egg Yolk Phospholipid Unsaturation and Its Impact on Neural Health in Alzheimer Disease Mice.
Bioactive Decellularized Extracellular Matrix Platform Integrating Multifunctional Nanozymes and Cell-Laden Microgels for Acute Liver Failure Treatment.
Terahertz Wave Desensitizes Ferroptosis by Inhibiting the Binding of Ferric Ions to the Transferrin.
The PAR6B-PRKCI-PAR3 complex influences alveolar regeneration in patients with the emphysema subtype of chronic obstructive pulmonary disease.
RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer.
Tumor vascular endothelial cells promote immune escape by upregulating PD-L1 expression via crosstalk between NF-κB and STAT3 signaling pathways in nasopharyngeal carcinoma.
Efficacy of Naringenin against aging and degeneration of nucleus pulposus cells through IGFBP3 inhibition.
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Isolation and characterization of bovine coronavirus variants with mutations in the hemagglutinin-esterase gene in dairy calves in China.
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m(6)A methylation: a novel mechanism early during radiation-induced liver injury.
Petroselinic Acid from Apiaceae Family Plants Ameliorates Autoimmune Disorders Through Suppressing Cytosolic-Nucleic-Acid-Mediated Type I Interferon Signaling.
Trp31 Residue of Trx-1 Is Essential for Maintaining Antioxidant Activity and Cellular Redox Defense Against Oxidative Stress.
Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development.
Cancer-secreted exosomal miR-1825 induces angiogenesis to promote colorectal cancer metastasis.
The Unveiled Novel regulator of Adeno-associated virus production in HEK293 cells.
Angiogenin-catalyzed cleavage within tRNA anticodon-loops identified by cP-RNA-seq.
eEF2K regulates pain through translational control of BDNF.
O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway.
Bispecific antibody simultaneously targeting AGR2 and PD1 mediates cytotoxic T-cell-induced antitumor response in AGR2-dependent manner and inhibits AGR2-induced PDL1 upregulation.
Al-Based Metal-Organic Nanoslice-Coupled Phospholipid Layer Enables Highly Enriched Biological External Vesicles.
KRAS(G12D)-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC.
CXCR4-targeted PET imaging in rheumatoid arthritis: a novel approach for monitoring disease activity and therapeutic response.
Hydrogen sulfide attenuates sepsis-induced cardiac dysfunction in infant rats by inhibiting the expression of cold-inducible RNA-binding protein.
Fucoidan ameliorates lipid accumulation, oxidative stress, and NF-κB-mediated inflammation by regulating the PI3K/AKT/Nrf2 signaling pathway in a free fatty acid-induced NAFLD spheroid model.
Estrogen Promotes Endometrial Cancer Development by Modulating ZNF626, SLK, and RFWD3 Gene Expression and Inducing Immune Inflammatory Changes.
Sulfonated albumin from hepatocytes accelerates liver fibrosis in nonalcoholic fatty liver disease through endoplasmic reticulum stress.
Luteolin alleviates diabetic cardiac injury related to inhibiting SHP2/STAT3 pathway.
FADS1 inhibition protects retinal pigment epithelium cells from ferroptosis in age related macular degeneration.
Sodium Butyrate Alleviates Heat Stress-Induced Oxidative Stress and Skeletal Muscle Homeostasis Disruption by Promoting Autophagy in Mice.
Isoliquiritigenin Ameliorates High-Fat Diet-Induced Obesity in Mice by Activating Brown Adipose Tissue.
Cryoablation-induced modulation of Treg cells and the TGF-β pathway in lung adenocarcinoma: implications for increased antitumor immunity.
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
Circular RNA APP contributes to Alzheimer's disease pathogenesis by modulating microglial polarization via miR-1906/CLIC1 axis.
Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers.
Activation of Adenosine Triphosphate-Gated Purinergic 2 Receptor Channels by Transient Receptor Potential Vanilloid Subtype 4 in Cough Hypersensitivity.
Bioinformatics analysis and validation of novel biomarkers and competitive endogenous RNA networks involved in pyroptosis in diabetic nephropathy.
Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as the First Bifunctional PI3Kδ Isoform Selective/Bromodomain and Extra-Terminal Inhibitors.
Identification of a Potent and Selective CDK9 Degrader as a Targeted Therapeutic Option for the Treatment of Small-Cell Lung Cancer.
Design, Synthesis and Anti-Inflammatory Evaluation of 3-Substituted 5-Amidobenzoate Derivatives as Novel P2Y(14) Receptor Antagonists via Structure-Guided Molecular Hybridization.
Multi-dimensional bio mass cytometry: simultaneous analysis of cytoplasmic proteins and metabolites on single cells.
Mettl3/Eed/Ythdc1 regulatory axis controls endometrial receptivity and function.
The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance.
Cumulative experience meets modern science: Remarkable effects of TongXieYaoFang formula on facilitating intestinal mucosal healing and secretory function.
Dahuang-Gancao decoction ameliorates testosterone-induced androgenetic alopecia in mice.
P2Y12 receptor-independent antiplatelet mechanism of cryptotanshinone: Network pharmacology and experimental validation of multi-target signaling pathways.
The bitter flavor of Banxia Xiexin decoction activates TAS2R38 to ameliorate low-grade inflammation in the duodenum of mice with functional dyspepsia.
Investigating the mechanism of Tongfeng Qingxiao Formula for improving gouty arthritis based on the neutrophil extracellular trapping network.
Naoxintong capsule attenuates heart damage after ischemic stroke via Nuclear factor-κB / Pyrin domain-containing protein 3 / Caspase-1 signaling.
Induction of the p21/CDK6 pathway and alteration of the immune microenvironment by the stem cell marker CBX3 in melanoma.
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis.
Nano-alkaline ion-excited NETs ablative eye drops promote ocular surface recovery.
Ferulic acid from Angelica sinensis (Oliv.) Diels ameliorates lipid metabolism in alcoholic liver disease via AMPK/ACC and PI3K/AKT pathways.
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
New idea of Fuke Qianjin capsule in treating sequelae of pelvic inflammatory disease: Anti-inflammatory in the early stage and reparative in the later stage.
Regulatory effects of yam (Dioscorea opposita Thunb.) glycoprotein on energy metabolism in C2C12 and 3T3-L1 cells and on crosstalk between these two cells.
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
NAT10 drives endometriosis progression through acetylation and stabilization of TGFB1 mRNA.
Genetic loss of Uchl1 leads to female infertility by affecting oocyte quality and follicular development.
Silencing of APEX1 triggers ferroptosis in clear cell renal cell carcinoma via APP-mediated activation of p53/xCT signaling.
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway.
Strontium-Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment.
miRNA-novel-216 regulated fatty acid composition and progesterone synthesis in goat granulosa cells by targeting the TPD52.
Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
In vitro-Digested Cervus nippon Velvet Antler Polypeptides Alleviate Alcoholic Liver Disease by Suppressing CYP2E1 Activity and Enhancing AMPK Signaling Pathway.
A dual absorption pathway of novel oyster-derived peptide-zinc complex enhances zinc bioavailability and restores mitochondrial function.
Lauryl gallate induces apoptosis via p38-MAPK phosphorylation and autophagy in chemoresistant human lung cancer cells.
Targeting MSR1 to Facilitate Efferocytosis: A Novel Strategy for Immune Homeostasis Regulation in Irreversible Pulpitis.
Role of TGF-β3 in Regulating Neural Crest Cell Fate and Craniofacial Development: Insights From Zebrafish Models.
von Willebrand Factor Deficiency Inhibits Endothelial-to-Mesenchymal Transition to Attenuate Pulmonary Fibrosis.
Krill Oil Reverses White Adipose Tissue Dysfunction by Inhibiting Macrophage M1 Polarization in Mice With Type 2 Diabetes.
Flavonols interrupt internalized bacteria hijacking cellular responses via suppressing oxidative stress induced cellular apoptotic death.
Wen-Shen-Tong-Luo-Zhi-Tong Decoction alleviates bone loss in aged mice by suppressing LONP1-mediated macrophage senescence.
Modified Xiao-Qing-Long-decoction prevents inflammation and promotes Nur77 expression in mice with acute respiratory distress syndrome by inhibiting HDAC7 expression.
Naringenin inhibits ferroptosis to reduce radiation-induced lung injury: insights from network Pharmacology and molecular docking.
Renal Denervation Improves Myocardial Mitochondrial Dysfunction and Myocardial Fibrosis by Inhibiting the NE/KLF15/renalase Pathway.
Tumor-derived exosomal miR-199b-5p promotes proliferation and epithelial-mesenchymal transition in non-small cell lung cancer by targeting CCNL1.
Hic-5 deficiency attenuates MAFLD by inhibiting neutrophils migration via the CXCL1-CXCR2 axis.
LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study.
Multi-omics analysis and validation of autophagy-related diagnostic biomarker in osteoarthritis.
Experimental study on the role and biomarker potential of CX3CR1 in osteoarthritis.
Identification of GBP6 as a potential prognostic biomarker in esophageal carcinoma by integrated bioinformatics analysis and experiment validation.
m6A reader IGF2BP2 mediates paclitaxel resistance in esophageal squamous cell carcinoma via FOXM1 mRNA stabilization.
Regulating SLC7A11/GSH/GPX4 axis by glucose dyshomeostasis to simultaneously promote disulfidptosis, cuproptosis and ferroptosis.
The mechanistic action of mogroside V in the alleviation of oxidative aging.
PACS2/PKCα/NOX4 pathway damaged the renal vascular endothelial barrier by promoting ROS production in diabetic nephropathy mice.
March6 Protects Against Acute Kidney Injury by Suppressing Renal Tubular Epithelial Cell Ferroptosis Through the Destabilization of P53 and ACSL4 Proteins.
MLKL-Mediated Necroptosis Predominantly Contributes to Immune-Associated Myocardial Damage.
SIRT6 Overexpression Enhances Diabetic Foot Ulcer Healing via Nrf2 Pathway Activation.
L1CAM enhances autophagy via inhibition of p38 phosphorylation in colorectal cancer development and progression.
Aucubin ameliorates diabetic kidney disease by restoring hGENCs autophagy through promoting phosphorylation of ATG4B protein.
Homozygous FAT1 frameshift mutation linked to glomerulotubular nephropathy with impaired cell adhesion and Rap1 signaling.
A novel APOL1 membrane-addressing domain mutation (p.T272I) in Chinese twins with FSGS: implications for podocyte injury and ion channel disruption.
Safflower injection against obesity-induced mice podocyte injury by improving insulin resistance through increasing renal INSR and eNOS expression.
Role of microvascular pericyte dysfunction in antibody-mediated rejection following kidney transplantation.
Gut microbiota-derived butyrate prevents aortic dissection via GPR41.
ARHGEF15 Promotes Endothelial Cell Migration Through the Regulation of STAT3 Signaling.
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Highly efficient prime editors for mammalian genome editing based on porcine retrovirus reverse transcriptase.
RNA and ChIP-sequencing analysis reveals SOX3 suppresses antiviral innate immunity through the AKT1-PTEN signaling axis.
Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m(6)A-YTHDF2-dependent mechanism.
Chicago Sky Blue 6B modulates MAPK/NF-kB pathway in rat knee osteoarthritis.
Stemness reducible effects of glyasperin A against NCCIT teratocarcinomas.
miR-28-5p targeted Rap1b attenuates splenic inflammation infiltration in immune thrombocytopenia.
Mulberry-derived carbon dots attenuate kidney fibrosis through direct inhibition of PI3K.
A bufalin and CRISPR/Cas9 ribonucleoprotein-loaded calcium lactate nanomedicine for pyroptosis/apoptosis and synergistic cancer immunotherapy.
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Muscle homing peptide modified liposomes loaded with EGCG improved skeletal muscle dysfunction by inhibiting inflammation in aging mice.
S100A4 regulates ferroptosis to suppress cell proliferation via the SLC7A11-GSH axis but facilitates Brucella infection in RAW264.7 macrophages.
Atractylodin inhibits ferroptosis in sepsis‑induced acute gastrointestinal injury via SIRT3/PRDX3.
Acute carbon monoxide poisoning induces renal inflammation and apoptosis via CCL4 upregulation and activation of the PI3K/Akt pathway in mice.
Aldehyde Dehydrogenase 6 Family Member A1 Facilitates Ti Implant Osseointegration in Hyperlipidemia.
Elevated cellular accumulation of endogenous and exogenous CoQ by altered intracellular trafficking.
The receptor tyrosine kinase ErbB2/HER2 governs CDK4 inhibitor sensitivity, timing, and irreversibility of the G1/S transition.
Identification and validation of the m6A-binding protein LRPPRC to promote tumorigenesis in multiple myeloma.
Evaluation of the inhibitory effects of emodin on Neospora caninum invasion and proliferation in vitro.
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion.
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
Sappanone A, a potential natural inhibitor of PI3K, alleviates metabolic dysfunction-associated steatohepatitis in experimental models.
Targeting PBK in the fibroblast-to-myofibroblast transition: A novel therapeutic strategy for IPF.
Progranulin deficiency exacerbates postoperative cognitive dysfunction via RhoA-mediated axodendritic impairment in aged mice.
RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia.
KDM4A-induced tumor senescence enhances the efficacy of immunotherapy by inhibiting AGT-PHB1 axis-mediated mitophagy in colorectal cancer.
Nanovaccine loaded with seno-antigen target senescent cells to improve metabolic disorders of adipose tissue and cardiac dysfunction.
Low Expression of Selenoprotein S Promotes Osteogenic Differentiation in Bone Marrow Mesenchymal Stromal Cells.
Involvement of impaired phosphate production and aberrant extracellular ATP signaling in the pathogenesis of hypophosphatasia: Analysis of ALPL-Knockout human iPS cell models.
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase-7 in chronic kidney disease.
Shenmai injection attenuates sepsis-associated acute lung injury by remodeling gut microbiota and restoring steroid hormone biosynthesis.
GCN2 regulates paclitaxel-induced neuropathic pain.
Exposure to EP-1 during lactation on maternal behavior, offspring early development, quinestrol transfer and relative receptors in maternal and offspring of Kunming mice.
Analysis of the Protective Mechanism of PGC-1α/NRF1/2/TFAM Pathway in Cortical Neuron Injury Induced by Oxidative Stress.
Hsa_circ_0007349 upregulates glutamate-ammonia ligase to modulate gingival fibroblast wound healing.
Gut microbes-spinal connection is required for itch sensation.
Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate.
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches.
Porcine reproductive and respiratory syndrome virus activates the pentose phosphate pathway via the ROS/HIF-1α/G6PD axis to promote viral replication.
Identification of compounds targeting porcine reproductive and respiratory syndrome virus nsp3 and evaluation of their antiviral efficacy.
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and in vivo.
The inhibitory and anti-inflammatory effects of TMP269 on peste des petits ruminants virus replication.
Antibody-dependent enhancement of ORFV uptake into host cells.
Injectable hydrogel-mediated co-delivery of oncolytic adenovirus and melphalan for retinoblastoma control and vision preservation.
The cytoskeletal protein smoothelin maintains homologous recombination repair by stabilizing RAD51 in an HUWE1-dependent manner in colorectal cancer.
Platycodin D inhibits non-small cell lung cancer bone metastasis by inducing ferroptosis through miR-877-3P/PNMA5 regulatory axis.
Hydroxytyrosol improved insulin resistance in male offspring born to high-fat diet dams by remodeling gut microbiota.
Context-Specific Metabolic Alterations in HPRT1 Knockout Cells Within a 3D Culture System.
METTL14 Regulates the Expression of Genes Related to Interferon, Interleukin and MHC Class I in Nasopharyngeal Carcinoma Cells.
CircMYO9A inhibits influenza A virus replication by dampening haemagglutinin cleavage via increasing SERPINE1/PAI-1 expression.
Glutamate promotes CCL2 expression to recruit tumor-associated macrophages by restraining EZH2-mediated histone methylation in hepatocellular carcinoma.
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
HOXA13 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating SLC7A11 and SLC3A2.
Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ.
The RNA-binding protein Quaking modulates cell proliferation through the SFRP1 mediated Wnt signaling pathway in NIH3T3 fibroblasts.
N2 neutrophils induce cell stemness reprogramming to promote gastric cancer progression via exosomal miRNAs.
C20orf27 regulates colorectal cancer growth and metastasis based on different lipid levels.
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR-NFκB Pathway.
Steroid Receptor Coactivator-1 Drives Tumor-Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion.
A machine learning-based glycolysis and fatty acid metabolism-related prognostic signature is constructed and identified ACSL5 as a novel marker inhibiting the proliferation of breast cancer.
Melatonin improves synaptic morphological plasticity of adolescent male rats after perinatal BDE-209 exposure via SIRT1-mediated LIMK1 and CREB signaling.
Pachymic Acid Suppresses Endometrial Cancer Cell Migration by Inhibiting the NR3C1/TGF-β/Smad Signaling Pathway.
Myosins 1e/f at the podosome base regulate podosome dynamics and promote macrophage migration.
Bioinspired pH-sensitive liposomes for quercetin delivery to synergize with 5- FU in gastric cancer therapy.
S-palmitoylation-related genes in Crohn's disease: Bioinformatic identification and validation.
Identification of potential biomarkers associated with mitochondrial oxidative stress in idiopathic pulmonary arterial hypertension via bioinformatic and experimental analysis.
NMDA receptors coordinate brain vascular development via neuron-to-endothelial tip cell crosstalk in zebrafish.
The Cx43-Mediated Autophagy Mechanism Influences Triple-Negative Breast Cancer Through the Regulation of Rab31.
CXCL10/CXCR3 axis facilitates the M2 polarization of macrophages in colorectal cancer via activating RAF.
Monitoring rapid degradation of NANOG reveals UTP15 maintains pluripotency by regulating nascent transcripts.
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
Screening and identification of differentially expressed miRNA and mRNA for intervertebral disc degeneration on bioinformatics.
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
The SREBF2-ACOT7 axis promotes tumor progression and predicts prognosis in diffuse large b-cell lymphoma.
Cross-Talk Between Hedgehog and PDGFRα Pathways in mMSCs Modulates Alveolar Bone Regeneration.
Autophagy-dependent secretion of ENO1 mediates chemoresistance of glioblastoma and tumor microenvironment remodeling.
TRIP13 alters mitochondrial function and promotes bortezomib resistance in multiple myeloma.
In silico design, synthesis and biological evaluation of 2-benzyl-5-(2-methoxybenzyl)-1,3,4-oxadiazole derivates as allosteric deoxyhypusine synthase (DHPS) inhibitors for melanoma treatment.
Lack of intestinal Mucin-1 impairs intestinal epithelial barrier and promotes metabolic dysfunction-associated steatotic liver disease in male mice.
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis.
Human peripheral osteoclast-precursor-development patterns reveal the significance of RPS17-dependent ribosome synthesis to Ankylosing Spondylitis lesions.
CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis.
SLC25A3 promotes hepatocellular carcinoma progression by inducing mitochondrial dysfunction and chromatin remodeling.
Echinacoside as a Novel Ferroptosis Inducer in Hepatocellular Carcinoma: Mechanistic Insights from TP53/SLC7A11/GPX4 Pathway Modulation.
VAMP5 promotes glioma progression through bioinformatics analysis clinical correlation and functional validation.
E4BP4-Driven Circadian SLC6A1 Expression Governs Tiagabine Chronoefficacy in Temporal Lobe Epilepsy.
Identification and functional characterization of genes associated with lipopolysaccharide in lung adenocarcinoma.
IL-1β-stimulated bone mesenchymal stem cell-derived exosomes promote cutaneous wound healing by inhibiting SIRT6/NLRP3 pathway.
A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment.
Targeting TDP1 phosphorylation by the natural product imperatorin promotes DNA repair and cardiac regeneration.
The Therapeutic Effect and Mechanism of Lactobacillus gardneri on Nonalcoholic Fatty Liver Disease.
1-Deoxynojirimycin Combined with Theaflavins Targets PTGS2/MMP9 to Exert a Synergistic Hypoglycemic Effect.
Integrated serum metabolomics reveal molecular mechanism of Xietu Hemu prescription on metabolic dysfunction-associated steatotic liver disease-related obesity.
Sestrin2 Knockdown Impairs Proliferation, Migration, Invasion, and Apoptosis in OSCC Cells via PI3K/AKT/mTOR and MAPK Pathways.
Obacunone alleviated the development of polycystic ovary syndrome via inhibiting STAT3 phosphorylation.
Hypoxic preconditioned mesenchymal stem cell-derived exosomes alleviate oxidative stress-induced cardiomyocyte apoptosis through miR-486-5p.
IGF2BP3-STAT3-METTL3 axis promotes malignant progression in hepatocellular carcinoma (HCC).
Rna analysis of the regulation of expression and alternative splicing in polycystic ovarian syndrome.
GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma.
The crosstalk between ubiquitination and GlcNAcylation of CHAF1A regulates HIV-1 latency and reactivation.
SLC44A1 deficiency impedes myelin development in the central nervous system.
The protein denitrosylase SCoR2 regulates lipogenesis and fat storage.
Loss of ELF2 drives topotecan resistance in retinoblastoma revealed by genome-wide CRISPR-Cas9 screening.
Identification of senescence-associated drivers of tumour growth and progression using a novel microarray platform.
The METTL3-YTHDC1 axis mediates architectural RNA m(6)A modification to modulate the integrity of chromatin TADs in MLLr + AML genome.
KAT2A affects the inflammatory progression of lupus nephritis through multilevel regulation of cGAS.
PAK2 promotes CTC cluster formation by phosphorylating E-cadherin to enhance cell-cell adhesion in breast cancer.
[Morinda officinalis polysaccharide delays osteoarthritis mouse chondrocyte degeneration by modulating the glycolysis-pyroptosis axis via targeting the lncRNA XIST].
PLAAT2 facilitates the development of pancreatic cancer and serves as a predictor of resistance to chemotherapy.
The Ku80-p53-SIRT1 axis in DNA damage response contributes to sporadic and familial ALS and FTD.
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
Intestinal clock shapes sleep-wake cycle via sustaining glutamine homeostasis.
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
USP25 deubiquitinates cytosolic METTL3 to impede glioma proliferation via an m6A-independent pathway.
Cochlear endoplasmic reticulum stress causes connexin 26 degradation is involved in age-related hearing loss.
ZDHHC9 and spermine metabolism: a palmitoylation-driven pathway to prostate carcinogenesis.
mRNA-lipid nanoparticle vaccines provide protection against lethal Nipah virus infection.
Targeting TRIM59 impairs RNA splicing and promotes neuroblastoma differentiation and therapeutic responses.
Optogenetic control of biomolecular organization reveals distinct roles of phase separation in RTK signaling.
Long noncoding RNA BMPR1B-DT promotes anoikis and reduces proliferation in ovarian cancer.
From Microbiota to Metabolomics: How Corylus heterophylla Fisch. Male Flower Extract Shields Mice from Cognitive Decline.
Sestrin 2 Regulates Milk Protein Synthesis through a LAT1/mTOR Pathway.
Disrupted inhibin B synthesis due to Sox9 hyper-palmitoylation in Sertoli cells impairs spermatogenesis via paracrine effects.
GALNT3 is a novel target driving lymphomagenesis via O-glycosylation of FGFR2.
FTO-mediated m6A modification regulates the osteogenic differentiation of ADSCs by targeting FOXO1.
Exploring the role of mitochondrial dysfunction-related genes in osteoporosis using weighted gene co-expression network analysis and machine learning.
Aluminum exposure induces ferroptosis in spermatogenic cells of mice through iron overload and lipid peroxidation.
Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy†.
Novel compound heterozygous mutations in plasminogen (p.Gly568Arg/p.Ala620Thr) impair protein structure and function in type II deficiency: mechanistic insights into a hereditary thrombogenic disorder.
RHOA regulates mitochondria-ER contact sites through modulation of the VAPB/PTPIP51 tether.
HPDA-based tubule-targeting nanoplatform alleviates oxidative stress and ferroptosis for the reversal of renal interstitial fibrosis.
Human umbilical cord-derived mesenchymal stem cells ameliorate non-alcoholic fatty liver disease via activating TFEB-mediated autophagy in male mice.
LAX1 as a core biomarker in Alzheimer's disease and periodontitis via the STAT signaling pathway.
Integrative analysis reveals NFIL3 as a prognostic marker in glioblastoma associated with anesthesia and circadian rhythm genes.
Low dose IFNγ remodels enhancer landscape to potentiate mesenchymal stromal cell activation.
The Combined Hypoglycemic Effect of Quercetagetin and Lutein from Marigold and Related Molecular Mechanisms in Mice.
The methyltransferase N6amt1 regulates hippocampal neurogenesis through 6 mA modification of Txnrd3 DNA.
Upregulated endoplasmic reticulum oxidoreductin 1-like protein alpha at the mother-fetus interface of preeclampsia promotes trophoblast cell migration and invasion.
Circ_0001741 regulates proliferation and invasion in ESCC via the miR-194-5p/E2F3 axis.
MCARE enhances SERCA1 activity in fast-twitch muscle to maintain calcium handling and muscle integrity.
The SCD5 Gene Modulates Adipogenic Differentiation via the WNT5B Signaling Pathway in Xinjiang Brown Cattle.
PML Is Limiting NLRP3 Inflammasome Activity in Human Endothelial Cells.
Let-7f-5p Inhibits PRRSV Replication by Regulating Lipid Metabolic Reprogramming in Infected Cells.
Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11.
Targeting MCM6 Enhances Melphalan Chemosensitivity in Retinoblastoma by Modulating DNA Damage Response.
The Actin Histidine methyltransferase SETD3 is a CHD1 lysine di-methyltransferase.
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Involvement of Integrin β3 O-Glycosylation in Human Cytomegalovirus Internalization Into Fibroblasts.
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
Functional study of two siblings with isolated growth hormone deficiency and pituitary MR imaging abnormalities caused by a novel HESX1 variant.
ZEB1 Contributes to Drug Resistance Through Canonical Wnt Signaling in Lung Cancer.
The Synergic Inhibition of Wilforlide A With Cisplatin in Lung Cancer Is Mediated Through Caspase-3 and NFκB Signaling.
Mechanism of lncRNA WARS2-IT1 promoting angiogenesis of glioma through miR-299-3P/VEGFA axis and activating PI3K/AKT signaling pathway.
The oncogenic role of SPOCK1 in lung carcinoma by promoting immune evasion and its related mechanisms.
Biodentine Counteracts the Aging Process of Human Dental Pulp Stem Cells Through Wnt/β-Catenin Pathway.
Targeting ATM enhances radiation sensitivity of colorectal cancer by potentiating radiation-induced cell death and antitumor immunity.
Taxifolin Inhibits Platelet Activation and Thrombosis by Regulating the PI3K/Akt and MAPK Signaling Pathways.
Prolonged Fructose Overconsumption Activates Original Biosynthetic and Metabolic Pathways of Endogenous Purine in Rats.
SPP1(+) Venous Endothelial Cells and CRABP2(+) Tumor Cells Contribute to Favorable Body and Tail Pancreatic Ductal Adenocarcinoma Tumor Microenvironment.
α-Enolase and γ-Enolase Expression in Enriched S- and N-Type SH-SY5Y Cells: Regulatory Role of Cathepsin X.
Ginsenoside Rg1 mitigates myocardial ischemia/reperfusion injury by inhibiting NLRP3-mediated pyroptosis.
IFIT3 inhibits transmissible gastroenteritis virus (TGEV) infection by promoting the phosphorylation of TBK1 and STAT1, which enhances the innate immune response.
METTL1-driven epitranscriptomic enhancement of TXNDC12 boosts c-Myc stability through USP5 in HNSCC.
The role of microparticles in oxidative stress and inflammation in patients with vascular intimal hyperplasia.
Cadmium treatment induces oxidative damage and apoptosis in vitro skeletal muscle cells.
MLKL triggers NLRP3 activation in sodium arsenite-induced myocardial necroinflammation.
An engineered M2 macrophage-derived exosomes-loaded electrospun biomimetic periosteum promotes cell recruitment, immunoregulation, and angiogenesis in bone regeneration.
Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration.
SGLT2i continuously prevents cardiac hypertrophy by reducing ferroptosis via AMPK up-regulation.
Fibroblast Growth Factor 21 Confers Protection Against Asthma Through Inhibition of NLRP3 Inflammasome Activation.
CircIRAK3 Promotes Neutrophil Extracellular Trap Formation by Improving the Stability of ELANE mRNA in Sepsis.
S100A9 Inhibition Mitigates Acute Pancreatitis by Suppressing RAGE Expression and Subsequently Ameliorating Inflammation.
Chronic Arsenic Exposure Causes Alzheimer's Disease Characteristic Effects and the Intervention of Fecal Microbiota Transplantation in Rats.
Yinchenhao Decoction Combined with Praziquantel Ameliorates Inflammation and Hepatic Fibrosis in Schistosoma japonicum-Infected Mice.
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
β-Catenin interacts with canonical RBPs including MSI2 to associate with a Wnt signalling mRNA network in myeloid leukaemia cells.
Ileal FXR Knockdown Ameliorates MASLD Progression in Rats via Modulating Bile Acid Metabolism Mediated by Gut Microbiota.
Sanguisorba officinalis L. and Sophora japonica L. Inhibit Angiogenesis in Ulcerative Colitis.
Danggui Buxue Decoction Combined with Borneol Improves Cyclophosphamide-Induced Myelosuppression by Inhibiting CDK2.
Single-cell sequencing reveals the role of IL-33 (+) endothelial subsets in promoting early gastric cancer progression.
Eupatilin mitigates ICH-induced brain injury via SOX2/SLC7A11 regulation of ferroptosis.
Novel compound heterozygous MRTFA gene variants cause multiple dysfunctions of neutrophils and autoinflammation.
Ethanol extract of Sauropus spatulifolius and its active constituents attenuate LPS-induced acute lung injury via NF-κB inhibition and Nrf2 activation.
Honokiol rescues progranulin deficiency in pathogen-induced and genetically driven neurodegeneration: Bridging veterinary models with therapeutic development.
Silencing PIM1 inhibits ENO1-induced AKT activation and attenuates fibrillogenesis during spinal cord injury-induced skeletal muscle atrophy.
A novel programmed cell death signature predicts clinical outcomes in clear cell renal cell carcinoma and identifies PLK1 as a therapeutic target.
Role and mechanism of RPA1 in the development and progression of glioma.
Paeoniflorin protected UVA-exposed skin fibroblasts from caspase-3/GSDME mediated pyroptosis.
The pathogenicity of a novel frame-shift variant c.2321delC of PROM1 in an autosomal recessive cone-rod dystrophy pedigree may be associated with augment of autophagy.
MiR-223-3p inhibits hippocampal neurons injury and exerts anti- anxiety/depression-like behaviors by directly targeting NLRP3.
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Astrocytic AEG-1 drives neuroinflammation and enhances seizure susceptibility.
p66shc exacerbates the progression of obstructive nephropathy through apoptosis, mitochondrial damage, and EMT.
P2X7 receptor is essential for ST36-attenuated cardiac fibrosis upon beta-adrenergic insult.
CD19(+)IL-10(+) regulatory B cells induced by IL-12p35 regulates functional T-cell subsets in patients with immune thrombocytopenia.
Molecular mechanism for the interaction of MOG1 with the intracellular loop II of cardiac sodium channel Na(v)1.5 and its role in arrhythmias.
Excessive ultra-processed foods exposure aggravates ulcerative colitis via macrophage ferroptosis.
The Long Noncoding RNA TUG1 Is Down-Regulated in Osteonecrosis of the Femoral Head and Enhances the Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by Stimulating the Wnt/β-Catenin Pathway.
Cilostazol attenuates vascular inflammation via the regulation of TICAM1/IRF3 signaling pathway.
Tumor necrosis factor alpha-induced activation of SREBP2 promotes cholesterol biosynthesis in cholestasis.
ARHGAP11A is a potential prognostic biomarker and therapeutic target for pancreatic adenocarcinoma.
Rhynchophylline as an agonist of sirtuin 3 ameliorates endothelial dysfunction via antagonizing mitochondrial damage of endothelial progenitor cells.
Dysregulation of CRY1 impairs brain thyroid hormone pathway and promotes anxiety-like behavior in male mice.
Irg1 mediates inhibition of A20-triggered NF-κB signaling cascade in tilapia macrophages during early immune response.
Mechanism of sulforaphane in treatment of pancreatic cancer cell based on network pharmacology and in vitro experiments.
A novel designed fully peptide-based PROTAC, FPP29, demonstrates its potent cytotoxic effects to liver cancer HCCLM3 cells by targeting FOXM1.
Exogenous Nucleotides Supplementation Attenuates Age-Related Sarcopenia.
Analysis of hepatitis B virus integration identifies KMT2B as a novel cancer-related gene in pancreatic cancer.
Unveiling the renoprotective mechanisms of self-assembled herbal nanoparticles from Scutellaria barbata and Scleromitrion diffusum in acute kidney injury: A nano-TCM approach.
Deciphering the prognostic signature of nonsmall cell lung cancer using cisplatin resistance and circulating tumor cell-related gene analysis.
Curdione inhibits the proliferation of human uterine leiomyomas by targeting YTHDF1.
Diosgenin promoted OPCs differentiation via blocking GLUR2/GAPDH interaction in a pilocarpine rat model of epilepsy.
USP5-Rich Apoptotic Extracellular Vesicles Regulate Nucleus Pulposus Cells Apoptosis and DNA Damage Repair by Preventing E2F1 Proteasomal Degradation.
Modulating intracellular calcium dynamics with alkaloids: A novel strategy against oxidative neurodegeneration.
Diminution of HSP75 disrupts intestinal epithelial barrier by inciting mPTP opening in ulcerative colitis.
HnRNPR promotes non-small cell lung cancer progression by protecting XB130 mRNA from XRN1- and DIS3L2-mediated degradation.
Hedgehog pathway inhibitor HhAntag suppresses virus infection via the GLI-S1PR axis.
GRHL3 specifically initiated by the TP63 transcription factor promotes the metastasis of squamous cell carcinogenesis.
RUNX1 Is an Independent Prognostic Marker Involved in Immune Infiltration and Therapeutic Responses in Clear Cell Renal Cell Carcinoma Patients Through Cluster Regulation With RUNX2.
Tongue squamous cell carcinoma-derived exosomes miR-21-5p affect tumor progression via promoting M2 macrophage polarization.
Gut microbiota promote the propagation of pathologic α-syn from gut to brain in a gut-originated mouse model of Parkinson's disease.
Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models.
UTX Responds to Nanotopography to Suppress Macrophage Inflammatory Response by Remodeling H3K27me3 Modification.
LIMK1 as a Novel Kinase of β-Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5.
ALKBH5 mediates FGF21 m6A demethylation in human bone marrow mesenchymal stem cells under high glucose conditions.
ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation.
The Key Flavor Substance in Zanthoxylum Preventing Alzheimer's Disease through Insulin Signaling.
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats.
Camellia japonica Flower Extract and the Active Constituent Hyperoside Repair DNA Damage Through FUNDC1-Mediated Mitophagy Pathway for Skin Anti-Aging.
SCAP Interacts with Trim27 to Promote Vascular Neointimal Hyperplasia by Regulating the Stability and Ubiquitination of IκBα.
Exploring the functional and prognostic roles of EPHX4 in pancreatic cancer: Insights from bioinformatics and experimental validation.
Glucuronolactone improves lung injury caused by PRRSV and DON co-challenge by enhancing the Nrf2-mediated antioxidant capacity in weaning piglets.
RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation.
Analysis of the prognostic and immune role of MCM6 in pan-cancer and experimental validation in lung adenocarcinoma cells.
Molecular mechanisms of cryoablation-mediated lung cancer suppression unveiled by non-coding RNA regulatory network profiling.
Complement Receptor 3 Regulates Microglial Exosome Release and Related Neurotoxicity via NADPH Oxidase in Neuroinflammation Associated with Parkinson's Disease.
miR-30a enhanced RIG-I-mediated type I interferon antiviral response by targeting USP14.
Phospholipase Cε1 activates Rap1 signaling pathway to promote proliferation, EMT and angiogenesis of choriocarcinoma cells.
Aggregation potency and proinflammatory effects of SARS-CoV-2 proteins.
Trimethylamine N-oxide Induced Chronic Kidney Injury by Triggering PANoptosis.
Role of Carvedilol in Inhibiting the Proliferation and Migration of Vascular Smooth Muscle Cells by Upregulating microRNA-145 Expression.
CDK11 Mediates Autophagy to Promote Breast Cancer Cell Proliferation and Migration by Regulating BCL-2.
Galnt4 Knockdown Modulates Lysosomal Function to Reduce Foam Cell Formation and Attenuate Atherosclerotic Plaque Progression.
25HC Depleted PMs-Accessible Cholesterol to Restrict SFTSV Entry and Infectious-EVs Mediated Infection.
Lipid metabolites as biomarkers and therapeutic targets in oral squamous cell carcinoma.
Role of the transcription factor SOX8 in hepatocellular carcinoma development and lymph node metastasis.
Identification and validation of a novel lymph node metastasis-related model for papillary thyroid carcinoma to predict the prognosis.
IRAK-M regulates NTHi-induced inflammation via JNK and NF-κB signal pathways.
Engineered MAP30ER: A plant toxin-derived platform for EGFR-Targeted delivery of protein and chemotherapeutic payloads.
Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.
Comprehensive bioinformatic analysis identifies potential therapeutic drugs for CryAB (R120G)-related cardiomyopathy.
M1-BMDMs with Wnt5a deletion attenuate liver fibrosis by suppression of Wnt5a/Frizzled 2 axis in hepatic progenitors.
Sex-dependent behavioral and neuronal alterations in the F2 generation of a neurodevelopmental mouse model for schizophrenia.
Non-SMC condensin I complex subunit H promotes cell proliferation and inhibits cell apoptosis of clear cell renal cell carcinoma by activating the PI3K/AKT pathway.
OTUB2/NR4A1 restrains the development of preeclampsia by suppressing macrophage M1 polarization.
Jianpi Huayu Jiedu Decoction prevents the progression of H. pylori and MNU-induced gastric precancerous lesions by inhibiting ferroptosis and remodeling linoleic acid metabolism.
Mechanisms and synergistic effects of the active components of Xanthocerais lignum in inhibiting rheumatoid arthritis through the modulation of the biological behavior of synovial cells.
A Dual-Specificity d-Peptide Antagonist of MDM2 and MDMX for Antitumor Immunotherapy.
Activated Schwann cells promote tumor growth in colon cancer.
Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics.
Bleomycin promotes cellular senescence and activation of the cGAS-STING pathway without direct effect on fibrosis in an idiopathic pulmonary fibrosis model.
Enhanced BEST2 expression in keratinocytes alleviates psoriatic inflammation.
High ELK3 expression is associated with the wild type IDH1 in glioma and enhances infiltration of M2 macrophages.
HERC5 induces podocyte injury in LN by mediated IRF3 ISGylation to promote the production and overactivation of IFN-β in podocytes.
S100a8 inhibitor Paquinimod attenuates coal dust-induced pulmonary fibrosis via blocking neutrophils-S100a8-Tlr4-macrophages signaling axis.
Novel therapeutic approach in periodontitis: Sulforaphane attenuates disease progression via Nrf2-mediated antioxidant defense.
HADHB mediates 5-fluorouracil sensitivity in colorectal cancer.
The study of JAZF1-mediated apoptosis of decidual stromal cells by activating the NF-κB signaling pathway in spontaneous preterm birth.
CircCRIM1 promotes the translation of HIF-1α protein through its interaction with PTBP3 and enhances malignant progression and angiogenesis in glioblastoma.
Solanum lyratum-Derived Solalyraine A1 Suppresses Non-Small Cell Lung Cancer Through Regulation of Exosome Secretion and Related Protein Biomarkers.
MSC-derived exosomes improve endometrial fibrosis via the lncRNA IGF2R/ miR-143-5p/AQP8 axis.
DHRS9 promotes malignant progression of ovarian cancer through SQSTM1.
Degraded Polysaccharides from Noni (Morinda citrifolia L.) juice Mitigate Glucose Metabolism Disorders by Regulating PI3K/AKT-Nrf2-GSK3β Signaling Pathways in HepG2 Cells.
Extracellular matrix stiffness reduces DNA 6 ma level to facilitate colorectal cancer progression via disrupting P53 binding to CDKN1A promoter.
NOLC1 suppresses immunochemotherapy by inhibiting p53-mediated ferroptosis in gastric cancer.
PRMT2-mediated upregulation of miR-323-3p in sensory neurons promotes trigeminal neuropathic pain by targeting Kv2.1 channels.
A multifaceted strategy for intra- and extracellular nucleic acid regulation to alleviate intervertebral disc degeneration.
Conditional immortalization of mesenchymal stem cells and their extracellular vesicles therapy for interstitial cystitis/bladder pain syndrome.
Spautin-1 inhibits the growth of diffuse large B-cell lymphoma by inducing mitochondrial damage-mediated PANoptosis and anti-tumor immunity.
Sodium-glucose cotransporter 2 inhibitors alleviate renal fibrosis in diabetic kidney disease by inhibiting Hmgcs2 and Btg2 in proximal tubular cells.
Ultrasound-actuated platelet mimetic nanomotors enable targeted piezocatalytic ROS storm for precision thrombolysis.
African swine fever virus A179L inhibits interferon induced transmembrane protein 1 activation of NF-κB pathway.
Systems Network Integration of Transcriptomic, Proteomic, and Bioinformatic Analyses Reveals the Mechanism of XuanYunNing Tablets in Meniere's Disease via JAK-STAT Pathway Modulation.
Heat shock protein family H member 1 HSPH1 expression correlates with progression and prognosis of hepatocellular carcinoma.
CAF-derived exosomes drive the FGF4/SHH feedback loop by encapsulating GREM1 in non-small cell lung cancer.
NLRP3 promotes NK cell-mediated cytotoxicity and inhibits colorectal cancer development via the NKG2D signaling pathway.
Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation.
Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1.
VILMIR is a trans-acting long noncoding RNA that enhances the host interferon response in human epithelial cells.
FBXO42 promotes hepatocellular carcinoma progression via mediating p57Kip2 ubiquitination and degradation.
mRNA decapping enzyme2 DCP2 expression correlates with progression and prognosis of hepatocellular carcinoma.
Collagen alpha-5(IV) chain activation by nuclear factor 1/C promotes nasopharyngeal carcinoma progression.
Drug-Free Approach to Regulate Undruggable Proto-Oncogene MYC Using Biomimetic Porous Nanoparticles for Cancer Immunotherapy.
Isorhamnetin protects against D-GalN/LPS-induced acute liver injury in mice through anti-oxidative stress, anti-inflammation, and anti-apoptosis.
Gut-resident Phascolarctobacterium succinatutens decreases fat accumulation via MYC-driven epigenetic regulation of arginine biosynthesis.
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
Targeting ATF4-DDIT4/TXNIP induced mitochondrial dysfunction and ferroptosis: ISRIB as novel therapy for septic cardiomyopathy.
Gut-derived Faecalibaculum rodentium exerts anti-cancer effects on colorectal cancer by modulating PDPN-CLEC-2 signaling pathway.
Establishment and evaluation of a patient-derived organoids-based xenograft model of primary aldosteronism using [(18)F]AlF-NOTA-pentixather PET/CT: bridging preclinical and clinical imaging.
AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria.
CD99 is a potential diagnostic and immunological biomarker in pan-cancer.
FEN1 plays a key role in the transition from HSIL to CSCC.
CDKN1A and EGR1 are key genes for endoplasmic reticulum stress-induced ferroptosis in MASH.
Cholecystectomy-related gut microbiota dysbiosis exacerbates colorectal tumorigenesis.
Nintedanib inhibits neovascularization and subretinal fibrosis in a laser-induced choroidal neovascularization mouse model.
Cu(OH)(2) nanopesticide induced liver dysfunction in mice by targeting lipoylated tricarboxylic acid cycle proteins via ferredoxin 1.
NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing.
P75(NTR) activation limits CD21(lo) B cell subsets expansion in response to autoimmune-inducing challenges.
LncRNA SNHG5 modulates cell proliferation and migration through the miR-92a-3p/BTG2 axis in gastric cancer by the PI3K/AKT pathway.
Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3.
Synthesis of USP5-IN-1 derivatives as novel USP5 inhibitors with potent activity against cholangiocarcinoma cells.
Granzyme B as a potential biological target in toxic encephalopathy: A big data-based exploratory analysis.
Mitochondrial-dependent apoptosis and STAT3 activation induced by oxidative stress in pemphigus vulgaris.
A novel neutrophil extracellular trap-related gene signature for predicting glioblastoma prognosis.
Circadian Rhythm Cascade SIRT1/PGC-1α/BMAL1 Pathway Regulates Nitroglycerin-Induced Chronic Migraine.
Integrative analysis and experimental validation identify the role of CD44 and Nucleolin in regulating gliogenesis following spinal cord injury.
The Hsp40 co-chaperone DNAJC7 modifies polyglutamine but not polyglycine aggregation.
A rapid and efficient red-light-activated Cre recombinase system for genome engineering in mammalian cells and transgenic mice.
Analysis of the Role of KLF4 in the Regulation of Porcine Epidemic Diarrhea Virus Infection.
Celastrol Activates SIRT1/PGC-1α/Nrf2 Axis to Inhibit Oxidative Damage for Subconjunctival Fibrosis Alleviation.
Estrogen increases Setdb1 cytoplasmic localization to stabilize Serpinh1 and improve protein homeostasis in osteoblasts.
Intranasal administration of exosomes derived from adipose mesenchymal stem cells ameliorates depressive-like behaviors and inhibits inflammation via AMPK/mTOR-mediated autophagy.
Stage-dependent efficacy of short-chain fatty acids in amyotrophic lateral sclerosis: Insights into autophagy and neuroprotection.
Pericyte loss: a key factor inducing brain Aβ40 accumulation and neuronal degeneration in cerebral amyloid angiopathy.
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
MSC-derived exosomes alleviate oxidative stress-induced lysosomal membrane permeabilization damage in degenerated nucleus pulposus cells via promoting m6A demethylation of Nrf2.
AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis.
Flavonoid Extract of Senecio scandens Buch.-Ham. Ameliorates CTX-Induced Immunosuppression and Intestinal Damage via Activating the MyD88-Mediated Nuclear Factor-κB Signaling Pathway.
USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment.
Panobinostat potentiates adagrasib-induced cell death by triggering autophagy in human non-small cell lung cancer.
Hua Yu Xiao Zheng decoction induces ectopic endometrial stromal cell senescence via inhibiting the PI3K/AKT signaling.
CNPY2 modulates senescence-associated secretory phenotype in tendon stem/progenitor cells.
Klotho improves Der p1-induced bronchial epithelial cell damage by inhibiting endoplasmic reticulum stress to regulate mitochondrial function.
Key role of the CSE/transsulfuration pathway in macrophage phenotypic change under iron overload.
Cordycepin Ameliorates Kainic Acid-Induced HT22 Cell Neurotoxicity by Activating GPR120-Mediated Mitophagy.
Esketamine alleviated cardiomyocyte ferroptosis induced by oxygen-glucose deprivation/reoxygenation (OGD/R) via cyclic GMP-AMP synthase interactor.
Co-delivery of fucoxanthin and Twist siRNA using hydroxyethyl starch-cholesterol self-assembled polymer nanoparticles for triple-negative breast cancer synergistic therapy.
BEND6 promotes RNA viruses' replication by inhibiting innate immune responses.
Generation of Myeloid-Specific Bmal1 Knockout Mice and Identification of Bmal1-Regulated Ferroptosis in Macrophages.
BTK and YKL-40 Levels and Their Association with Acute AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder.
A Novel Heterozygous IHH c.331_333del Mutation Identified in a Fetus with Brachydactyly Type A1 Causes IHH Protein Maturation Failure in HEK293T Cells.
EGFR tyrosine kinase inhibitor ZZC4 overcomes acquired resistance to gefitinib.
PRMT5 Inhibition Enhances Therapeutic Efficacy of Cisplatin via Mediating miR-29b-3p-Mcl-1 Expression in Lung Adenocarcinoma.
Lactobacillus murinus alleviates insulin resistance via promoting L-citrulline synthesis.
TRIM35 Negatively Regulates the cGAS-STING-Mediated Signaling Pathway by Attenuating K63-Linked Ubiquitination of STING.
TRPV4 drives the progression of leiomyosarcoma by promoting ECM1 generation and co-activating the FAK/PI3K/AKT/GSK3β pathway.
Caffeine improves hypoxia/reoxygenation induced neuronal cell injury through inhibiting cellular ferroptosis: an in vitro study.
Differential regulation of pruritic sensation and emotion by cannabinoid type 1 receptors on mPFC glutamatergic and GABAergic neurons.
Synergistic restoration of spinal cord injury through hyaluronic acid conjugated hydrogel-polydopamine nanoparticles combined with human mesenchymal stem cell transplantation.
Effects of Huoxue Chubi decoction on protein kinase B-mammalian target of rapamycin autophagy pathway in scleroderma Balb/c model mice.
Inhibition of CCN5 Protects Against Apoptosis and Endoplasmic Reticulum Stress in Bisphenol A-Induced Sertoli Cells via p38/JNK MAPK Signaling Pathway.
CBX2 as a therapeutic target in colorectal cancer: insights into the altered chromatin accessibility via RUNX1-CBX2-MAP4K1 axis.
Peroxisomal biogenesis factor 11 as a novel target to trigger lipid biosynthesis and salt stress resistance in oleaginous Tetradesmus obliquus.
Iodoacetamide triggers ovarian dysfunction in mice through TGF-β signaling pathway and apoptosis.
Low molecular weight heparins promote migration and invasion of trophoblast cells through regulating the PI3K/AKT signaling pathway.
Prunus mume Alleviates Hyperuricemic Renal Injury: Insights From Network Pharmacology and Experimental Models.
Behavioral, biochemical, and molecular characterization of MPTP/p-intoxicated mice.
Transcription factor AP-2 Beta, a potential target of repetitive Transspinal magnetic stimulation in spinal cord injury treatment, reduced inflammation and alleviated spinal cord injury.
GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in metabolic dysfunction-associated steatohepatitis livers.
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders.
Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN.
Lycium barbarum polysaccharide mitigates high-fat-diet-induced skeletal muscle atrophy by promoting AMPK/PINK1/Parkin-mediated mitophagy.
The α- to γ-enolase switch: The role and regulation of γ-enolase during oligodendrocyte differentiation.
HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3.
Sagittaria sagittifolia polysaccharide extract regulates Nrf2 to improve endoplasmic reticulum stress-mediated apoptosis in rat cataracts and HLEB3 cells.
Carboxymethyl polysaccharides from Poria cocos (Schw.) wolf: Structure, immunomodulatory, anti-inflammatory, tumor cell proliferation inhibition and antioxidant activity.
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss.
Contributing role and molecular basis of Vitamin D/Vitamin D receptor deficiency in hyperhomocysteinemia-induced cardiac hypertrophy.
Cross-species analysis of the nuclease Artemis highlights its evolving function in domesticating RAG-like transposons and residues that are crucial for activity.
Trans 10, cis 12-conjugated linoleic acid alleviates vascular fibrosis in obese mice.
Neutrophil-like cell membrane-coated metal-organic frameworks for siRNA delivery targeting NOX4 to alleviate oxidative stress in acute ischemic injury.
Conditional deletion of Pink1 in mesenchymal stem cells suppresses osteogenesis through downregulation of Apoh transcription.
Platelets promote metastasis of intrahepatic cholangiocarcinoma through activation of TGF-β/Smad2 pathway.
RGFP966 inhibits palmitic acid induced VSMCs phenotypic transition by targeting ATGL.
Regulation of the EGFR/PI3K/AKT signaling cascade using the Shengui Yangrong Decoction improves ovulation dysfunction and insulin resistance in polycystic ovary syndrome.
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Amino-modified IONPs potentiates ferroptotic cell death due to the release of Fe ion in the lysosome.
PCIF1 drives oesophageal squamous cell carcinoma progression via m6Am-mediated suppression of MTF2 translation.
Thermal proteome profiling (TPP) reveals NAMPT as the anti-glioma target of phenanthroindolizidine alkaloid PF403.
Targeting ceramide-induced microglial pyroptosis: Icariin is a promising therapy for Alzheimer's disease.
Application of 4D-Printed Magnetoresponsive FOGS Hydrogel Scaffolds in Auricular Cartilage Regeneration.
Multi-Omic Insight Into the Molecular Networks in the Pathogenesis of Coronary Artery Disease.
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
Proteomic screening identifies brusatol targets TGFβRII to suppresses non-small cell lung cancer metastasis.
Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα signaling pathway and inhibiting TGF-β1 and FHL1 signaling pathways.
Astaxanthin alleviates spinal nerve ligation-induced neuropathic pain by modulating propionic acid levels.
3-Hydroxypropionaldehyde modulates tryptophan metabolism to activate AhR signaling and alleviate ethanol-induced liver injury.
Canagliflozin-induced renal glutathione distribution mapping in non-diabetic male rat kidneys.
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Deficiency of HSF4 Increases the Secretion of Small Extracellular Vesicles via Upregulation of Chaperone-Mediated Autophagy.
Nuclear to Cytoplasmic Transport Is a Druggable Dependency in HDAC7-driven Small Cell Lung Cancer.
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Burn-Induced Gut Microbiota Dysbiosis Aggravates Skeletal Muscle Atrophy by Tryptophan-Kynurenine Mediated AHR Pathway Activation.
Phosphorylation of POU3F3 Mediated Nuclear Translocation Promotes Proliferation in Non-Small Cell Lung Cancer through Accelerating ATP5PF Transcription and ATP Production.
LINC00323 knockdown suppresses the proliferation, migration, and vascular mimicry of non-small cell lung cancer cells by promoting ubiquitinated degradation of AKAP1.
Identifying potential prognosis markers in relapsed multiple myeloma via integrated bioinformatics analysis and biological experiments.
Ginsenoside Rg1 exerts anti-arrhythmic effect by inhibiting I(CaL) through cAMP-PKA and PI3K-AKT signaling pathways in rat ventricular myocytes after myocardial ischemia-reperfusion injury.
Lancao decoction alleviates Alzheimer's disease: Depending on activating CaMKII to protect neuronal refunction by reducing β-amyloid in the hippocampus.
Proteomic analysis reveals that Acalypha australis L. mitigates chronic colitis by modulating the FABP4/PPARγ/NF-κB signaling pathway.
LncRNA H19 inhibited dermal papilla cell senescence process through miR-29a by targeting Wnt/β-catenin signaling pathway.
Viral protease binds to nucleosomal DNA and cleaves nuclear cGAS that attenuates type I interferon.
The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses.
CSF2 promotes chemoresistance in colorectal cancer by regulating Notch pathway.
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau.
Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure.
CGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.
Identification and Functional Analysis of Cystathionine Beta-Synthase Gene Mutations in Chinese Families with Classical Homocystinuria.
Tauroursodeoxycholic Acid Induces Liver Regeneration and Alleviates Fibrosis Through GATA3 Activation.
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
Fumonisin B1 induces oxidative stress, inflammation and necroptosis in IPEC-J2 cells.
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis.
Iron Homeostasis-Regulated Adaptive Metabolism of PEGylated Ultrasmall Iron Oxide Nanoparticles.
Ozone exposure and increased risk of age-related macular degeneration: Evidence from nationwide cohort and toxicological studies.
Berberine Alleviates 1-Methyl-3-Nitro-1-Nitrosoguanidine- Induced Chronic Atrophic Gastritis in Rats.
Multi-omics analysis of copper metabolism-related molecular subtypes and risk stratification for osteosarcoma.
SIRT5-mediated BCAT1 desuccinylation and stabilization leads to ferroptosis insensitivity and promotes cell proliferation in glioma.
HNGF6A ameliorates oxidative stress-mediated mitochondrial dysfunction in degenerative meniscus.
Metformin attenuated depressive-like behaviors by suppressing TRPV1/NLRP3 mediated neuroinflammation in the hypothalamus of allergic rhinitis mice.
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Targeting the liquid-liquid phase separation of nucleocapsid broadly inhibits the replication of SARS-CoV-2 strains.
F-53B disrupts energy metabolism by inhibiting the V-ATPase-AMPK axis in neuronal cells.
Sodium propionate protects against bronchopulmonary dysplasia by inhibiting IL-17-mediated apoptosis of alveolar epithelial cells.
Therapeutic Target Discovery for Multiple Myeloma: Identifying Druggable Genes via Mendelian Randomization.
Chrysophanol Attenuates Cardiac Fibrosis and Arrhythmia by Suppressing the Endoplasmic Reticulum Stress/Pyroptosis Axis and Inflammation.
KIF14 plays a role in the regulation of the cell cycle and has implications for prognosis in clear cell renal cell carcinoma.
Zearalenone Depresses Lactation Capacity Through the ROS-Mediated PI3K/AKT Pathway.
Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.
The highly expressed GOLPH3 in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance.
The increased matrix stiffness caused by LOXL2 activates Piezo1 channels to promote the migration and invasion of cervical cancer cells.
Exposure to MC-LR activates the RAF/ERK signaling pathway, leading to renal inflammation and tissue damage in mice.
β-hydroxybutyrate facilitates mitochondrial-derived vesicle biogenesis and improves mitochondrial functions.
NUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix.
Role in Preventing Alcoholic Liver Disease Progression: A Comparative Study of Whole-Component Finger Citron Essential Oil and Its Major Component D-Limonene.
Dietary Fiber Intake Improves Osteoporosis Caused by Chronic Lead Exposure by Restoring the Gut-Bone Axis.
The autocrine motility factor receptor delays the pathological progression of Alzheimer's disease via regulating the ubiquitination-mediated degradation of APP.
Genome-wide CRISPR screening identifies LRP1 as an entry factor for SFTSV.
PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1.
Baicalin Relieves Glaesserella parasuis-Triggered Immunosuppression Through Polarization via MIF/CD74 Signaling Pathway in Piglets.
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER-phagy pathway.
HMOX1 as a Novel Biomarker for Glucose-Lipid Metabolism Disorder and T2DM: Systematic Bioinformatics Investigation and Experimental Verification.
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
Transcranial Magnetic Stimulation Alleviates Spatial Learning and Memory Impairment by Inhibiting the Expression of SARM1 in Rats with Cerebral Ischemia-Reperfusion Injury.
Granulosa cell RNA-Seq insights into senescence and sphingolipid metabolism disorder in PCOS: aspirin as a potential therapeutic drug.
A compound heterozygous mutation in ZP1 and two novel heterozygous cis mutations in ZP3 causes infertility in women presenting with empty follicle syndrome.
MMP1-induced NF-κB activation promotes epithelial-mesenchymal transition and sacituzumab govitecan resistance in hormone receptor-positive breast cancer.
RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria.
Dendrobine alleviates LPS-induced acute lung injury via activation of the PI3K/AKT/GSK3β pathway.
Development of a Long-Acting Interleukin-11 Antagonist for the Treatment of Renal Fibrosis.
Discovery of Novel SHP2 ATTEC Degraders against Pancreatic Ductal Adenocarcinoma Harboring KRAS(G12D) Mutations.
Kanglexin attenuates spinal cord injury by modulating pyroptosis and polarization via the PKA/NF-κB signaling pathway.
Apigenin-Mediated ESCRT-III Activation and Mitophagy Alleviate LPS-Induced Necroptosis in Renal Cells.
Neutrophil extracellular traps induced by neoadjuvant chemotherapy of breast cancer promotes vascular endothelial damage.
Lactiplantibacillus plantarum -derived extracellular vesicles alleviate acute lung injury by inhibiting ferroptosis of macrophages.
Intranasal Transplantation of Microbiota Derived from Parkinson's Disease Mice Induced Astrocyte Activation and Neurodegenerative Pathology from Nose to Brain.
Mitophagy Protects Against Cisplatin-Induced Injury in Granulosa Cells.
Comprehensive PTM profiling with SCASP-PTM uncovers mechanisms of p62 degradation and ALDOA-mediated tumor progression.
LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia.
Identification of a novel tRNA-derived small RNA fragment, tRF-16-2YU04DE, with the potential of inhibiting endometrial cancer progression.
Identifying PSIP1 as a critical R-loop regulator in osteosarcoma via machine-learning and multi-omics analysis.
Hydrogel-Based Bioactive Synthetic Skin Stimulates Regenerative Gas Signaling and Eliminates Interfacial Pathogens to Promote Burn Wound Healing.
Remodeling of Effector and Regulatory T Cells by Capture and Utilization of miRNAs Using Nanocomposite Hydrogel for Tumor-Specific Photothermal Immunotherapy.
Periostin-mediated activation of NF-κB signaling promotes tumor progression and chemoresistance in glioblastoma.
Curcumin prevents dexamethasone-induced activation of the pseudorabies virus in rat pheochromocytoma cells through the miR-155-5p-Aak1-Numb/Notch2 signalling axis.
RNA Methylation and Transcriptome Analysis Reveal Key Regulatory Pathways Related to Cadmium-Induced Liver Damage.
Calpain inhibition as a novel therapeutic strategy for aortic dissection with acute lower extremity ischemia.
Emodin alleviates the damage to lens epithelial cells in diabetic cataract by repressing the p53-mediated ferroptosis pathway.
Ribosome profiling reveals that post-transcriptional control of Nalf1 by heterogeneous nuclear ribonucleoprotein L is required for paclitaxel-induced neuropathic pain.
Faecalibacterium prausnitzii-derived outer membrane vesicles reprogram gut microbiota metabolism to alleviate Porcine Epidemic Diarrhea Virus infection.
HPV16 E7 inhibits HBD2 expression by down-regulation of ASK1-p38 MAPK pathway in cervical cancer.
MC-LR induced apoptosis in human embryonic kidney (HEK293) cells through activation of TNF-R1/RIPK1 pathway.
Co-Highly Expressed SLC17A9 and KCNH1 as Potential Prognostic Biomarkers and Therapeutic Targets in Clear Cell Renal Cell Carcinoma.
The m6A methyltransferase METTL3 affects ferroptosis in non-small cell lung cancer by regulating the PTEN/PI3K/AKT pathway.
Nobiletin Enhances Skeletal Muscle Mass and Modulates Bile Acid Composition in Diet-Induced Obese Mice.
Condensation of cellular prion protein promotes renal fibrosis through the TBK1-IRF3 signaling axis.
Synthesis of AgInS(2) quantum dots loaded with celastrol for induction of apoptosis and autophagy in hepatocellular carcinoma cells.
Activation of the hippocampal CA1 astrocyte Gq and Gi G protein-coupled receptors exerts a protective effect against attention deficit hyperactivity disorder.
The African swine fever virus MGF360-16R protein functions as a mitochondrial-dependent apoptosis inducer by competing with BAX to bind to the HSP60 protein.
Human long noncoding RNA VILMIR is induced by major respiratory viral infections and modulates the host interferon response.
Integrative analysis of bulk RNA and single-cell sequencing data reveals a liquid-liquid phase separation signature for clear cell renal cell carcinoma.
lncRNA NR_146969 promotes the progression of lung adenocarcinoma.
3,4-Dimethoxychalcone alleviates limb ischemia/reperfusion injury by TFEB-mediated autophagy enhancement and antioxidative response.
Discovery of novel sitolactone derivative leading to PANoptosis and differentiation of acute myeloid leukemia cells.
Cold atmospheric plasma drives USP49/HDAC3 axis mediated ferroptosis as a novel therapeutic strategy in endometrial cancer via reinforcing lactylation dependent p53 expression.
Synchronously Evoking Disulfidptosis and Ferroptosis via Systematical Glucose Deprivation Targeting SLC7A11/GSH/GPX4 Antioxidant Axis.
CCN1 is a therapeutic target upregulated in EML4-ALK mutant lung adenocarcinoma reversibly resistant to alectinib.
The dual HDAC/PI3K inhibitor CUDC-907 inhibits the growth and proliferation of MYC-driven Group 3 medulloblastoma.
RFX5 promotes the progression of triple-negative breast cancer through transcriptional activation of JAG1.
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
Mechanistic evaluation of Jiu Wei Qing Zhi Gao in non-alcoholic fatty liver disease: insights from network Pharmacology and experimental validation.
Therapeutic potential of naturally derived carbon dots in sepsis-associated acute kidney injury.
Covariation of scleral remodeling and PI3K/Akt signaling pathway in experimental myopia.
METTL3 Plays Regulatory Roles in Acute Pneumonia during Staphylococcus aureus Infection.
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Macrophage membrane enveloped on double-locked nanoplatform with right-side-out orientation to improving precise theranostic for atherosclerosis.
EBV enhances immunotherapy sensitivity in intrahepatic cholangiocarcinoma through cGAS-STING pathway activation.
Oxypeucedanin alleviates cisplatin-induced intestinal toxicity through impairing caspase-3/gasdermin E signaling.
Rnd3 Ameliorates Diabetic Cardiac Microvascular Injury via Facilitating Trim40-Mediated Rock1 Ubiquitination.
AZGP1 Attenuates Subretinal Fibrosis and Inhibits Epithelial-Mesenchymal Transition by Blocking the PI3K/AKT Signaling Pathway.
Tumor-derived miR-203a-3p potentiates muscle wasting by inducing muscle ferroptosis in pancreatic cancer.
Hesperidin produces antidepressant effects by activating AMPA receptor: enhancing synaptic proteins to promote hippocampal neuronal activities.
The TEAD4-DYNLL1 axis accelerates cell cycle progression and augments malignant properties of lung adenocarcinoma cells.
Ultrasmall Bi@Au Schottky Heterojunction with a High Potential Barrier for Amplifying Radioimmunotherapy.
DNA Methylation Mediates the Transcription of STAT4 to Regulate KISS1 During Follicular Development.
TLR4/Rac1/NLRP3 Pathway Mediates Amyloid-β-Induced Neuroinflammation in Alzheimer's Disease.
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Impact and mechanisms of drag-reducing polymers on shear stress regulation in pulmonary hypertension.
Glucosamine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress and inflammation.
Effects of Different Light Environments with Varying Spectral Composition on the Axial Lengths and Scleral Specificity Protein 1 and Collagen Type I Expression in Juvenile Guinea Pigs.
Taurine Improved Autism-Like Behaviours and Defective Neurogenesis of the Hippocampus in BTBR Mice through the PTEN/mTOR/AKT Signalling Pathway.
Chronic Ethanol Intake Impairs Niacin Nutritional Status in Mice.
Cytotoxicity and inhibitory potential of CUDC-101 in non-small cell lung cancer cells with rare EGFR L861Q mutation.
Diacylglycerol O-acyltransferase 2, a Novel Target of Flavivirus NS2B3 Protease, Promotes Zika Virus Replication by Regulating Lipid Droplet Formation.
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis.
Opioid growth factor receptor overexpression exerts anti-hepatocellular carcinoma effects by activating P16 and P21 to inhibit proliferation and migration of HepG2 cells.
The duration-dependent and sex-specific effects of neonatal sevoflurane exposure on cognitive function in rats.
Isoliquiritigenin Suppresses Breast Tumor Development by Enhancing Host Antitumor Immunity.
Exploring the impact of insufficient thermal ablation on hepatocellular carcinoma: NDST2 overexpression mechanism and its role in facilitating growth and invasion of residual cancer cells.
The Epstein-Barr virus-miRNA-BART6-5p regulates TGF-β/SMAD4 pathway to induce glycolysis and enhance proliferation and metastasis of gastric cancer cells.
MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1.
Development and Validation of the Diagnostic Model of 7 Gene in Endometriosis.
Network Pharmacology and In vitro Experimental Verification to Explore the Mechanism of Chaiqin Qingning Capsule in the Treatment of Pain.
The generation and characterization of a transgenic zebrafish line with lens-specific Cre expression.
Customized Sized Manganese Sulfide Nanospheres as Efficient T(1) MRI Contrast Agents for Enhanced Tumor Theranostics.
CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial Homeostasis.
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation.
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma.
The Mechanism of Action and Experimental Verification of Narenmandula in the Treatment of Postmenopausal Osteoporosis.
Genetic Polymorphisms of rs9949644 in MAPK4 Are Associated with Clinical Response to Methotrexate in Patients with Psoriasis.
LRG1 promotes the apoptosis of pulmonary microvascular endothelial cells through KLK10 in chronic obstructive pulmonary disease.
Trans 10, cis 12-conjugated linoleic acid reduced reproductive ability by disrupting the estrus cycle in female mice.
Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis.
Chemically Modified PPARγ mRNA Unleashes Adipogenic Potential in 3T3-L1-Predipocytes: An Approach for Accelerated Wound Healing.
Matrix Metalloproteinase 11 Promotes Migration and Invasion of Colorectal Cancer by Elevating Slug Protein.
Targeting the Ajuba/Notch axis increases the sensitivity of colon cancer cells to 5-fluorouracil.
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin.
Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide-Induced Inflammatory Microenvironment through NLRP3 Inhibition.
Identification and Verification of Hub Mitochondrial Dysfunction Genes in Osteoarthritis Based on Bioinformatics Analysis.
Conditioned Medium Derived From Human Dental Follicle Mesenchymal Stem Cells Alleviates Macrophage Proinflammatory Responses Through MAPK-ERK-EGR1 Axis.
KIF26B and CREB3L1 Derived from Immunoscore Could Inhibit the Progression of Ovarian Cancer.
Shh Signaling from the Injured Lung Microenvironment Drives BMSCs Differentiation into Alveolar Type II Cells for Acute Lung Injury Treatment in Mice.
Construction of the miRNA/Pyroptosis-Related Molecular Regulatory Axis in Abdominal Aortic Aneurysm: Evidence From Transcriptome Data Combined With Multiple Machine Learning Approaches Followed by Experiment Validation.
Genetically engineered macrophages derived from iPSCs for self-regulating delivery of anti-inflammatory biologic drugs.
Tumor-derived Exosomal ENO2 Modulates Polarization of Tumor-associated Macrophages through Reprogramming Glycolysis to Promote Progression of Diffuse Large B-cell Lymphoma.
BRD7 enhances the radiosensitivity of nasopharyngeal carcinoma cells by negatively regulating USP5/METTL3 axis-mediated homologous recombination repair.
NUSAP1 is Upregulated by Estrogen to Promote Lung Adenocarcinoma Growth and Serves as a Therapeutic Target.
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
Combination of TrxR1 inhibitor and lenvatinib triggers ROS-dependent cell death in human lung cancer cells.
Hypoxia-driven TNS4 fosters HNSCC tumorigenesis by stabilizing integrin α5β1 complex and triggering FAK-mediated Akt and TGFβ signaling pathways.
Dual role of CD73 as a signaling molecule and adenosine-generating enzyme in colorectal cancer progression and immune evasion.
Wenyang-Tianjing-Jieyu Decoction Improves Depression Rats of Kidney Yang Deficiency Pattern by Regulating T Cell Homeostasis and Inflammation Level.
High-dose radiation-induced immunogenic cell death of bladder cancer cells leads to dendritic cell activation.
ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.
HMGA2 as a prognostic and immune biomarker in hepatocellular carcinoma: Comprehensive analysis of the HMG family and experiments validation.
Sepsis induces the cardiomyocyte apoptosis and cardiac dysfunction through activation of YAP1/Serpine1/caspase-3 pathway.
PEI/MMNs@LNA-542 nanoparticles alleviate ICU-acquired weakness through targeted autophagy inhibition and mitochondrial protection.
LARP1 knockdown inhibits cultured gastric carcinoma cell cycle progression and metastatic behavior.
Hybrid Liposome-MSN System with Co-Delivering Potential Effective Against Multidrug-Resistant Tumor Targets in Mice Model.
Development of an Intelligent Reactive Oxygen Species-Responsive Dual-Drug Delivery Nanoplatform for Enhanced Precise Therapy of Acute Lung Injury.
Effective-Component Compatibility of Bufei Yishen Formula III Suppresses Mitochondrial Oxidative Damage in COPD: Via Pkm2/Nrf2 Pathway.
SiRNF8 Delivered by DNA Framework Nucleic Acid Effectively Sensitizes Chemotherapy in Colon Cancer.
Catalpol Enhances Osteogenic Differentiation of Human Periodontal Stem Cells and Modulates Periodontal Tissue Remodeling in an Orthodontic Tooth Movement Rat Model.
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Chuanxiong Renshen Decoction Inhibits Alzheimer's Disease Neuroinflammation by Regulating PPARγ/NF-κB Pathway.
Morin Regulates M1/M2 Microglial Polarization via NF-κB p65 to Alleviate Vincristine-Induced Neuropathic Pain.
Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis.
Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer.
N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-κB pathway in rats.
IRF2 Affects LPS- and IFN-γ-Induced Pro-Inflammatory Responses, Cell Viability, Migration and Apoptosis of Macrophages by Regulating IRG1.
Comparison of the Cecum Ligation and Puncture Method and the Intraperitoneal Lipopolysaccharide Injection Method for the Construction of a New-Onset Atrial Fibrillation Model of Sepsis.
Study on the Anti-Atherosclerotic Mechanisms of Xin-Tong-Tai Granule Through Network Pharmacology, Molecular Docking, and Experimental Validation.
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
NLRP3 Inflammasome Deficiency Alleviates Inflammation and Oxidative Stress by Promoting PINK1/Parkin-Mediated Mitophagy in Allergic Rhinitis Mice and Nasal Epithelial Cells.
The AGEs/RAGE Signaling Pathway Regulates NLRP3-Mediated Neuronal Pyroptosis After MCAO Injury in Lepr(-/-) Obese Rats.
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Haploinsufficiency of Cnot3 Aggravates Acid-Induced Acute Lung Injury Likely Through Transcriptional and Post-Transcriptional Upregulation of Pro-Inflammatory Genes.
Pretreatment with Indole-3-Propionic Acid Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction and Inflammation Through the AhR/NF-κB/NLRP3 Pathway.
Vitamin D Binding Protein: A Potential Factor in Geriatric COVID-19 Acute Lung Injury.
FcγRIIb Exacerbates LPS-Induced Neuroinflammation by Binding with the Bridging Protein DAP12 and Promoting the Activation of PI3K/AKT Signaling Pathway in Microglia.
New Insights into Roles of IL-7R Gene as a Therapeutic Target Following Intracerebral Hemorrhage.
Tuina Promotes Repair of Chronic Cervical Muscle Injury by Regulating Satellite Cell Proliferation and Differentiation and Inhibiting Myocyte Apoptosis.
Every-other-day fasting inhibits pyroptosis while regulating bile acid metabolism and activating TGR5 signaling in spinal cord injury.
Identification and Validation of Genes Related to Macrophage Polarization and Cell Death Modes Under Mycobacterium tuberculosis Infection.
Ubiquitination contributes to the regulation of GDP-mannose pyrophosphorylase B activity.
Knockdown of INPP5K compromises the differentiation of N2A cells.
Downregulation of NAT1 Expression is Associated with Poor Prognosis and Immune Infiltration in COAD.
Sodium Propionate Alleviates Atopic Dermatitis by Inhibiting Ferroptosis via Activation of LTBP2/FABP4 Signaling Pathway.
Integrating network pharmacology with experimental validation to investigate the mechanism of Wuwei Zishen formula in improving perimenopausal syndrome.
Role of ferroptosis in Porphyromonas gingivalis-induced impairment of epithelial junction.
Expression Analysis of FANCD2 in Endometrial Carcinoma.
KYNU Expression Promotes Cisplatin Resistance in Esophageal Cancer.
Development and Validation of the novel Cuproptosis- and Immune-related Signature for Predicting Prognosis in Hepatocellular Carcinoma.
Cuproptosis-related genes score and its hub gene GCSH: A novel predictor for cholangiocarcinomas prognosis based on RNA seq and experimental analyses.
Comprehensive analysis reveals TSPEAR as a prognostic biomarker in colorectal cancer.
Expression and role of FKBPL in lung adenocarcinoma.
ATP5J regulates microglial activation via mitochondrial dysfunction, exacerbating neuroinflammation in intracerebral hemorrhage.
Calycosin alleviates ferroptosis and attenuates doxorubicin-induced myocardial injury via the Nrf2/SLC7A11/GPX4 signaling pathway.
Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function.
Green carbon dots derived from Zingiberis Rhizoma Carbonisatum alleviate ovalbumin-induced allergic rhinitis.
Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.
IRF7-deficient MDBK cell based on CRISPR/Cas9 technology for enhancing IBRV replication.
In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma.
Protective effects of small RNAs encapsulated in Artemisia Capillaris-derived exosomes against non-alcoholic fatty liver disease.
Profiling hypoxia signaling reveals a lncRNA signature contributing to immunosuppression in high-grade glioma.
Microglial adenosine A(2A) receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.
Electroacupuncture may protect pulmonary dysplasia in offspring with perinatal nicotine exposure by altering maternal gut microbiota and metabolites.
Spermidine attenuates chondrocyte inflammation and cellular pyroptosis through the AhR/NF-κB axis and the NLRP3/caspase-1/GSDMD pathway.
KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.
Matrine regulates autophagy in ileal epithelial cells in a porcine circovirus type 2-infected murine model.
Dexmedetomidine regulates the anti-oxidation and autophagy of adipose-derived stromal cells under H(2)O(2)-induced oxidative stress through Nrf2/p62 pathway and improves the retention rate of autologous fat transplantation.
Zhachong Shisanwei pill drug-containing serum protects H(2)O(2)-Induced PC12 cells injury by suppressing apoptosis, oxidative stress via regulating the MAPK signaling pathway.
APP-CD74 axis mediates endothelial cell-macrophage communication to promote kidney injury and fibrosis.
The metabolomics changes in epididymal lumen fluid of CABS1 deficient male mice potentially contribute to sperm deformity.
Integrated bioinformatics analysis of nucleotide metabolism based molecular subtyping and biomarkers in lung adenocarcinoma.
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia.
Kumujan B suppresses TNF-α-induced inflammatory response and alleviates experimental colitis in mice.
Multi-omics evaluation of the prognostic value and immune signature of FCN1 in pan-cancer and its relationship with proliferation and apoptosis in acute myeloid leukemia.
Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD.
Colquhounia root tablet improves diabetic kidney disease by regulating epithelial-mesenchymal transition via the PTEN/PI3K/AKT pathway.
Conduction and validation of a novel mitotic spindle assembly related signature in hepatocellular carcinoma: prognostic prediction, tumor immune microenvironment and drug susceptibility.
SNAP25-induced MYC upregulation promotes high-grade neuroendocrine lung carcinoma progression.
Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways.
Wogonin protects against bleomycin-induced mouse pulmonary fibrosis via the inhibition of CDK9/p53-mediated cell senescence.
Bacteroides fragilis capsular polysaccharide A ameliorates ulcerative colitis in rat by recovering intestinal barrier integrity and restoring gut microbiota.
Unraveling the nexus of NAD+ metabolism and diabetic kidney disease: insights from murine models and human data.
The oxidant-antioxidant imbalance was involved in the pathogenesis of chronic rhinosinusitis with nasal polyps.
The role of metabolic memory in diabetic kidney disease: identification of key genes and therapeutic targets.
Development and verification of a manganese metabolism- and immune-related genes signature for prediction of prognosis and immune landscape in gastric cancer.
Anti-pulmonary fibrosis activity analysis of methyl rosmarinate obtained from Salvia castanea Diels f. tomentosa Stib. using a scalable process.
Cell-type specific effects of mineralocorticoid receptor gene expression suggest intercellular communication regulating fibrosis in skeletal muscle disease.
Characterization of the m(6)A regulators' landscape highlights the clinical significance of acute myocardial infarction.
Multi-omic analysis of precocious puberty girls: pathway changes and metabolite validation.
TRIM28 facilitates type I interferon activation by targeting TBK1.
Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins.
Protective effect of oxytocin on vincristine-induced gastrointestinal dysmotility in mice.
Integrated analysis reveals crosstalk between pyroptosis and immune regulation in renal fibrosis.
Association of tumour mutation burden with prognosis and its clinical significance in stage III gastric cancer.
In-silico analysis of TMEM2 as a pancreatic adenocarcinoma and cancer-associated fibroblast biomarker, and functional characterization of NSC777201, for targeted drug development.
ADAM9 drives the immunosuppressive microenvironment by cholesterol biosynthesis-mediated activation of IL6-STAT3 signaling for lung tumor progression.
SSH3 promotes pancreatic cancer proliferation and migration by activating the notch signaling pathway.
Polycomb repressive complex 1 modulates granulosa cell proliferation in early folliculogenesis to support female reproduction.
Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.
DEC1 is involved in TGF-β1-induced epithelial-mesenchymal transition of gastric cancer.
Anillin contributes to prostate cancer progression through the regulation of IGF2BP1 to promote c-Myc and MAPK signaling.
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy.
Aryl hydrocarbon receptor confers protection against macrophage pyroptosis and intestinal inflammation through regulating polyamine biosynthesis.
Comprehensive analysis of ferroptosis-related genes indicates that TRIM46 is a novel biomarker and promotes the progression of ovarian cancer via modulating ferroptosis and Wnt signaling pathway.
Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro.
Characterization of the function and clinical value of ERCC family genes in lung adenocarcinoma.
Revealing the mechanisms of RAC3 in tumor aggressiveness, the immunotherapy response, and drug resistance in bladder cancer.
Targeted inhibition of BET proteins in HPV16-positive head and neck squamous cell carcinoma reveals heterogeneous transcriptional responses.
USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53.
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Identification and validation of a gap junction protein related signature for predicting the prognosis of renal clear cell carcinoma.
MAPK-activated protein kinase 2 is associated with poor prognosis of glioma patients and immune inhibition in glioma.
Glutamine promotes the proliferation of intestinal stem cells via inhibition of TP53-induced glycolysis and apoptosis regulator promoter methylation in burned mice.
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Anti-inflammatory role of low-intensity pulsed ultrasound in inhibiting lipopolysaccharide-induced M1 polarization of RAW264.7 cells via Wnt2b/AXIN/β-catenin.
PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway.
Single-cell transcriptome reveals the heterogeneity of malignant ductal cells and the prognostic value of REG4 and SPINK1 in primary pancreatic ductal adenocarcinoma.
Circular RNA circMAN1A2 promotes ovarian cancer progression through the microRNA-135a-3p/IL1RAP/TAK1 pathway.
Reversal of cholestatic liver disease by the inhibition of sphingosine 1-phosphate receptor 2 signaling.
Quercetin alleviates PM(2.5)-induced chronic lung injury in mice by targeting ferroptosis.
Inhibition effect of copper-bearing metals on arterial neointimal hyperplasia via the AKT/Nrf2/ARE pathway in vitro and in vivo.
Sesamin alleviates lipid accumulation induced by elaidic acid in L02 cells through TFEB regulated autophagy.
Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice.
Identification of a novel Scn3b mutation in a Chinese Brugada syndrome pedigree: implications for Nav1.5 electrophysiological properties and intracellular distribution of Nav1.5 and Navβ3.
Circ_0007386 Promotes the Progression of Hepatocellular Carcinoma Through the miR-507/ CCNT2 Axis.
Changes of m(6)A Regulatory Proteins and Nrf2 Signaling Molecules in Liver Tissue of Type 2 Diabetes Mellitus Rats.
Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane.
GSDMB involvement in the pathogenesis of abdominal aortic aneurysm through regulation of macrophage non-canonical pyroptosis.
ABCG2 shields against epilepsy, relieves oxidative stress and apoptosis via inhibiting the ISGylation of STAT1 and mTOR.
CircFAM188A Regulates Autophagy via miR-670-3p and ULK1 in Epithelial Ovarian Carcinoma.
Dexmedetomidine improves mitophagy and pyroptosis through the ALKBH5/FUNDC1 axis during epidural-related maternal fever.
A fungal-binding agglutinin in the skin slime of Japanese flounder (Paralichthys olivaceus) is glyceraldehyde 3-phosphate dehydrogenase.
MiR-483-3p promotes dental pulp stem cells osteogenic differentiation via the MAPK signaling pathway by targeting ARRB2.
Increased CCT5 expression is a potential unfavourable factor promoting the growth of nasopharyngeal carcinoma.
Surgical Debulking Modifies Notch Signaling and May Improve Vismodegib Effectiveness for Locally Advanced Basal Cell Carcinoma.
Effects of multi-walled carbon nanotubes and halloysite nanotubes on plasma lipid profiles and autophagic lipolysis pathways in mouse aortas and hearts.
Tangeretin alleviates inflammation and oxidative response induced by spinal cord injury by activating the Sesn2/Keap1/Nrf2 pathway.
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine.
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death.
Photosensitive AIEgens sensitize bacteria to oxidative damage and modulate the inflammatory responses of macrophages to salvage the photodynamic therapy against MRSA.
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Identification and immunological characterization of genes associated with ferroptosis in Alzheimer's disease and experimental demonstration.
DCBLD2 deletion increases hyperglycemia and induces vascular remodeling by inhibiting insulin receptor recycling in endothelial cells.
Rhodojaponin VI ameliorates podocyte injury related with MDM2/Notch1 pathway in rat experimental membranous nephropathy.
Anti‑epileptic mechanism of isopimaric acid from Platycladi cacumen based on network pharmacology, molecular docking and biological validation.
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
Fucoidan alleviates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via Nrf2/GPX4 pathway.
Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis.
Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis.
Cyclic guanosine monophosphate-adenosine monophosphate synthetase/stimulator of interferon genes signaling aggravated corneal allograft rejection through neutrophil extracellular traps.
Inhibition of KIAA1429/HK1 axis enhances the sensitivity of liver cancer cells to sorafenib by regulating the Warburg effect.
STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage.
Pyrimidine compounds BY4003 and BY4008 inhibit glioblastoma cells growth via modulating JAK3/STAT3 signaling pathway.
Functional regulation of microRNA-184 in the replication and infection of Autographa californica multiple nucleopolyhedrovirus.
TRIM56 restricts Coxsackievirus B infection by mediating the ubiquitination of viral RNA-dependent RNA polymerase 3D.
Bacterial ubiquitin ligases hijack the host deubiquitinase OTUB1 to inhibit MTORC1 signaling and promote autophagy.
The potential of ribonucleotide reductase M2 as a novel prognostic maker and therapeutic target to inhibit medulloblastoma proliferation, migration, and invasiveness.
Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms.
Transcriptional regulation of Znt family members znt4, znt5 and znt10 and their function in zinc transport in yellow catfish (Pelteobagrus fulvidraco).
AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease.
Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice.
Osteoclast-derived exosomes influence osteoblast differentiation in osteoporosis progression via the lncRNA AW011738/ miR-24-2-5p/ TREM1 axis.
Enriched environment treatment promotes neurofunctional recovery by regulating the ALK5/Smad2/3/Gadd45β signaling pathway in rats with cerebral ischemia /reperfusion injury.
Red nucleus mGluR1 and mGluR5 facilitate the development of neuropathic pain through stimulating the expressions of TNF-α and IL-1β.
Inhibition of GBP1 alleviates pyroptosis of human pulmonary microvascular endothelial cells through STAT1/NLRP3/GSDMD pathway.
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
PKC-δ Promotes IL-1β-Induced Apoptosis of Rat Chondrocytes and Via Activating JNK and P38 MAPK Pathways.
HIF-1α knockdown attenuates inflammation and oxidative stress in ischemic stroke male rats via CXCR4/NF-κB pathway.
Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism.
The role of cytidine 5'-triphosphate synthetase 1 in metabolic rewiring during epithelial-to-mesenchymal transition in non-small-cell lung cancer.
Puerarin suppresses macrophage M1 polarization to alleviate renal inflammatory injury through antagonizing TLR4/MyD88-mediated NF-κB p65 and JNK/FoxO1 activation.
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
Role of RIPK3 in lipid metabolism and postnatal overfeeding-induced metabolic disorders in mice.
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
GLP-2 ameliorates D-galactose induced muscle aging by IGF-1/Pi3k/Akt/FoxO3a signaling pathway in C2C12 cells and mice.
The role of α7nAchR and PD-L1 in neuroimmune regulation of keloid treatment.
USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1.
Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis.
Genetically Engineered Membrane-Coated Nanoparticles for Enhanced Prostate-Specific Membrane Antigen Targeting and Ferroptosis Treatment of Castration-Resistant Prostate Cancer.
Hsp90 Promotes Gastric Cancer Cell Metastasis and Stemness by Regulating the Regional Distribution of Glycolysis-Related Metabolic Enzymes in the Cytoplasm.
Bortezomib elevates intracellular free Fe(2+) by enhancing NCOA4-mediated ferritinophagy and synergizes with RSL-3 to inhibit multiple myeloma cells.
Selenium nanoparticles promotes intestinal development in broilers by inhibiting intestinal inflammation and NLRP3 signaling pathway compared with other selenium sources.
Resolving the current controversy of use and reuse of housekeeping proteins in ageing research: Focus on saving people's tax dollars.
SP1/CTR1-mediated oxidative stress-induced cuproptosis in intervertebral disc degeneration.
MiRNA-132/212 encapsulated by adipose tissue-derived exosomes worsen atherosclerosis progression.
Systematic identification of post-transcriptional regulatory modules.
Human Umbilical Cord Mesenchymal Stem Cells-Derived Extracellular Vesicles for Rat Jawbone Regeneration in Periapical Periodontitis.
Distinct modes of coupling between VCP, an essential unfoldase, and deubiquitinases.
GALNT6 promotes bladder cancer malignancy and immune escape by epithelial-mesenchymal transition and CD8(+) T cells.
A New Mouse Model for Usher Syndrome Crossing Kunming Mice with CBA/J Mice.
Bioinspired Collagen Scaffold Loaded with bFGF-Overexpressing Human Mesenchymal Stromal Cells Accelerating Diabetic Skin Wound Healing via HIF-1 Signal Pathway Regulated Neovascularization.
10-hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence in male mice preclinically.
BAP1 regulates HSF1 activity and cancer immunity in pancreatic cancer.
Copy number amplification-induced overexpression of lncRNA LOC101927668 facilitates colorectal cancer progression by recruiting hnRNPD to disrupt RBM47/p53/p21 signaling.
Deubiquitinase USP5 regulates RIPK1 driven pyroptosis in response to myocardial ischemic reperfusion injury.
Nobiletin alleviates macrophage M2 polarization by activating AMPK-mTOR-mediated autophagy in pulmonary fibrosis mice.
Construction of a prognostic model with exosome biogenesis- and release-related genes and identification of RAB27B in immune infiltration of pancreatic cancer.
Gliomedin drives gastric cancer cell proliferation and migration, correlating with a poor prognosis.
ER stress modulates Kv1.5 channels via PERK branch in HL-1 atrial myocytes: Relevance to atrial arrhythmogenesis and the effect of tetramethylpyrazine.
Identification of diagnostic markers and molecular clusters of cuproptosis-related genes in alcohol-related liver disease based on machine learning and experimental validation.
Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.
KIFC3 promotes the proliferation, migration and invasion of non-small cell lung cancer through the PI3K/AKT signaling pathway.
2D MXene Nanosheets with ROS Scavenging Ability Effectively Delay Osteoarthritis Progression.
Trehalose Rescues Postmenopausal Osteoporosis Induced by Ovariectomy through Alleviating Osteoblast Pyroptosis via Promoting Autophagy.
Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity.
Differential proteins from EVs identification based on tandem mass tags analysis and effect of Treg-derived EVs on T-lymphocytes in COPD patients.
Empagliflozin alleviates obesity-related cardiac dysfunction via the activation of SIRT3-mediated autophagosome formation.
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
DDIT3 switches osteogenic potential of BMP9 to lipogenic by attenuating Wnt/β-catenin signaling via up-regulating DKK1 in mesenchymal stem cells.
A Gain-of-Function Cleavage of TonEBP by Coronavirus NSP5 to Suppress IFN-β Expression.
Exposure to Succinate Leads to Steatosis in Non-Obese Non-Alcoholic Fatty Liver Disease by Inhibiting AMPK/PPARα/FGF21-Dependent Fatty Acid Oxidation.
Treadmill Exercise Facilitates Synaptic Plasticity in APP/PS1 Mice by Regulating Hippocampal AMPAR Activity.
Etelcalcetide ameliorates bone loss in chronic kidney disease-mineral and bone disorder by activation of IRF7 and necroptosis pathways.
Baicalin Ameliorates Depression-like Behaviors via Inhibiting Neuroinflammation and Apoptosis in Mice.
Invention of circRNA promoting RNA to specifically promote circRNA production.
AntigenBoost: enhanced mRNA-based antigen expression through rational amino acid substitution.
TiO2 nanotube enhance osteogenesis through Kindlin-2/Integrin β1/YAP pathway-mediated mechanotransduction.
Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis.
Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2.
GAS6 as a potential target to alleviate neuroinflammation during Japanese encephalitis in mouse models.
Myotis bat STING attenuates aging-related inflammation in female mice.
Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD.
Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells.
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
HSV-1 immune escapes in microglia by down-regulating GM130 to inhibit TLR3-mediated innate immune responses.
TRIM16 mitigates impaired osteogenic differentiation and antioxidant response in D-galactose-induced senescent osteoblasts.
BUB1 potentiates gastric cancer proliferation and metastasis by activating TRAF6/NF-κB/FGF18 through m6A modification.
Radix Rehmanniae Praeparata promoted zebrafish fin regeneration through aryl hydrocarbon receptor-dependent autophagy.
Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N(6)-methyladenosine (m(6)A) mediated silencing of SLC7A11.
Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells via the IGF1R/AKT1/RHOA signaling pathway.
Zinc oxide nanoparticles disrupt the mammary epithelial barrier via Z-DNA binding protein 1-triggered PANoptosis.
Insufficient KIF15 during porcine oocyte ageing induces HDAC6-based microtubule instability.
Dissecting the role of SMN multimerization in its dissociation from the Cajal body using harmine as a tool compound.
NSDHL promotes the degradation of sting in cholangiocarcinoma.
Huaier inhibits autophagy and promotes apoptosis in T-cell acute lymphoblastic leukemia by down-regulating SIRT1.
Molecular basis of CX-5461-induced DNA damage response in primary vascular smooth muscle cells.
C-di-GMP@ZIF-8 nanocomposite injectable hydrogel based on modified chitosan and hyaluronic acid for infected wound healing by activating STING signaling.
Ocotillol Derivatives Mitigate Retinal Ischemia-Reperfusion Injury by Regulating the Keap1/Nrf2/ARE Signaling Pathway.
DVL/GSK3/ISL1 pathway signaling: unraveling the mechanism of SIRT3 in neurogenesis and AD therapy.
Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission.
SQLE-a promising prognostic biomarker in cervical cancer: implications for tumor malignant behavior, cholesterol synthesis, epithelial-mesenchymal transition, and immune infiltration.
Single-cell RNA-seq analysis of rat molars reveals cell identity and driver genes associated with dental mesenchymal cell differentiation.
Kidney targeting and modulating macrophage polarization through AMPK signaling: Therapeutic mechanism of berberine in uric acid nephropathy.
Downregulation of the (pro)renin receptor alleviates ferroptosis-associated cardiac pathological changes via the NCOA 4-mediated ferritinophagy pathway in diabetic cardiomyopathy.
Identification and validation of sialyltransferase ST3Gal5 in bladder cancer through bioinformatics and experimental analysis.
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization.
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Endosialin-positive CAFs promote hepatocellular carcinoma progression by suppressing CD8(+) T cell infiltration.
MicroRNA-522-3p promotes brain metastasis in non-small cell lung cancer by targeting Tensin 1 and modulating blood-brain barrier permeability.
Intervention of epithelial mesenchymal transition against colon cancer cell growth and metastasis based on SOX21/POU4F2/Hedgehog signaling axis.
RNF31-mediated IKKα ubiquitination aggravates inflammation and intestinal injury through regulating NF-κB activation in human and mouse neonates.
Revitalizing gut barrier integrity: role of miR-192-5p in enhancing autophagy via Rictor in enteritis.
Network pharmacology prediction to discover the potential pharmacological action mechanism of Rhizoma Dioscoreae for liver regeneration.
CXCR3 participates in asymmetric division of mouse oocytes by modulating actin dynamics.
Inhibition of 5-HT alleviates PTSD-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats.
The SARS-unique domain (SUD) of SARS-CoV-2 nsp3 protein inhibits the antiviral immune responses through the NF-κB pathway.
EIF4A3 is stabilized by the long noncoding RNA BC200 to regulate gene expression during Epstein-Barr virus infection.
Rhein inhibits M1 polarization of BV2 microglia through MAPK/IκB signalling pathway and reduces neurotoxicity caused by neuroinflammation.
RBM25 depletion suppresses the growth of colon cancer cells through regulating alternative splicing of MNK2.
YAP-LAMB3 axis dictates cellular resistance of pancreatic ductal adenocarcinoma cells to gemcitabine.
Role of NF-κB signaling pathway in H(2)O(2)-induced oxidative stress of hiPSCs.
Mechanism of Treadmill Exercise Combined with Rich Environmental Stimulation to Improve Depression in Post-stroke Depression Model Rats.
Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells.
Ginseng polysaccharide promotes the apoptosis of colon cancer cells via activating the NLRP3 inflammasome.
A novel small-molecule PCSK9 inhibitor E28362 ameliorates hyperlipidemia and atherosclerosis.
Disordered regions in the IRE1α ER lumenal domain mediate its stress-induced clustering.
Glycyrrhizin Protects Submandibular Gland Against Radiation Damage by Enhancing Antioxidant Defense and Preserving Mitochondrial Homeostasis.
Identification of serum metabolites associated with aristolochic acid nephropathy severity and insights into the underlying mechanism.
Transcutaneous Auricular Vagus Nerve Stimulation Ameliorates Preeclampsia-Induced Apoptosis of Placental Trophoblastic Cells Via Inhibiting the Mitochondrial Unfolded Protein Response.
Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
Screening potential antileukemia agents from duckweed: Integration of chemical profiling, network pharmacology, and experimental validation.
Fusobacterium nucleatum dysregulates inflammatory cytokines and NLRP3 inflammasomes in oral cells.
NAT10/CEBPB/vimentin signalling axis promotes adenoid cystic carcinoma malignant phenotypes in vitro.
METTL3 inhibitor STM2457 impairs tumor progression and enhances sensitivity to anlotinib in OSCC.
GLS2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neurons.
Neuron-specific deficiency of autophagy increases neuronal loss in traumatic brain injury.
Duck plague virus-encoded microRNA dev-miR-D28-3p inhibits viral replication via targeting UL27.
GDH1 exacerbates renal fibrosis by inhibiting the transcriptional activity of peroxisome proliferator-activated receptor gamma.
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
IRG1/Itaconate inhibits proliferation and promotes apoptosis of CD69(+)CD103(+)CD8(+) tissue-resident memory T cells in autoimmune hepatitis by regulating the JAK3/STAT3/P53 signalling pathway.
2,5-Dihydroxyacetophenone attenuates acute kidney injury induced by intra-abdominal infection in rats.
Lenvatinib acts on platelet‑derived growth factor receptor β to suppress the malignant behaviors of gastric cancer cells.
Mitogen-activated protein kinase kinase kinase 1 facilitates the temozolomide resistance and migration of GBM via the MEK/ERK signalling.
Regulation of autophagy by ST3GAL2-mediated α2-3 sialylated glycosphingolipids in hepatic encephalopathy.
Identification of two novel B-cell epitopes located on the spike protein of swine acute diarrhea syndrome coronavirus.
Human organic anion transporting polypeptide 1B3 (OATP1B3) is more heavily N-glycosylated than OATP1B1 in extracellular loops 2 and 5.
The suppression of OTUD7B by miR-491-5p enhances the ubiquitination of VEGFA to suppress vascular mimicry in non-small cell lung cancer.
Exploring neuron-specific steroid synthesis and DHEAS therapy in Alzheimer's disease.
The LAMB3-EGFR signaling pathway mediates synergistic Anti-Cancer effects of berberine and emodin in Pancreatic cancer.
Diarylpropionitrile-stimulated ERβ nuclear accumulation promotes MyoD-induced muscle regeneration in mdx mice by interacting with FOXO3A.
LIM kinase 2 activates cardiac fibroblasts and exacerbates postinfarction left ventricular remodeling via crosstalk between the canonical and non-canonical Wnt pathways.
Oncoprotein-induced transcript 3 protein-enriched extracellular vesicles promotes NLRP3 ubiquitination to alleviate acute lung injury after cardiac surgery.
Orthodontic tension promotes cementoblast mineralization by regulating autophagy.
Targeting SOCS2 alleviates myocardial fibrosis by reducing nuclear translocation of β-catenin.
AMPK induces PIAS3 mediated SUMOylation of E3 ubiquitin ligase Smurf1 impairing osteogenic differentiation and traumatic heterotopic ossification.
High-dose vitamin C attenuates radiation-induced pulmonary fibrosis by targeting S100A8 and S100A9.
Anti-CRMP2 antibody induces anxiety-like behavior and increases pyramidal neuron excitability in mice.
Peroxiredoxin 4 deficiency induces accelerated ovarian aging through destroyed proteostasis in granulosa cells.
PPARγ/NF-κB axis contributes to cold-induced resolution of experimental colitis and preservation of intestinal barrier.
Ilexgenin A inhibits lipid accumulation in macrophages and reduces the progression of atherosclerosis through PTPN2/ERK1/2/ABCA1 signalling pathway.
Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis.
Seno-antigen-pulsed dendritic cell vaccine induce anti-aging immunity to improve adipose tissue senescence and metabolic abnormalities.
Artemether ameliorates acetaminophen-induced liver injury through Nrf2 pathway.
Red nucleus mGluR2 but not mGluR3 mediates inhibitory effect in the development of SNI-induced neuropathological pain by suppressing the expressions of TNF-α and IL-1β.
Mechanisms of Shufeng Jiedu Capsule in treating bacterial pneumonia based on network pharmacology and experimental verification.
Design, synthesis and biological evaluation of novel quinazoline-derived EGFR/HER-2 dual-target inhibitors bearing a heterocyclic-containing tail as potential anti-tumor agents.
A rationally designed CD19 monoclonal antibody-triptolide conjugate for the treatment of systemic lupus erythematosus.
Xianling Lianxia formula improves the efficacy of trastuzumab by enhancing NK cell-mediated ADCC in HER2-positive BC.
Gui Qi Zhuang Jin Decoction ameliorates mitochondrial dysfunction in sarcopenia mice via AMPK/PGC-1α/Nrf2 axis revealed by a metabolomics approach.
Phenylpropanoid-rich maize root extract serves as a natural antidepressant.
TRPM8 overexpression suppresses hepatocellular carcinoma progression and improves survival by modulating the RTP3/STAT3 pathway.
Chronic stress causes ovarian fibrosis to impair female fertility in mice.
YTHDF1 facilitates esophageal cancer progression via augmenting m6A-dependent TINAGL1 translation.
Exercise preconditioning mitigates brain injury after cerebral ischemia-reperfusion injury in rats by restraining TIMP1.
Oleanolic acid attenuates obesity through modulating the lipid metabolism in high-fat diet-fed mice.
Orientin promotes diabetic wounds healing by suppressing ferroptosis via activation of the Nrf2/GPX4 pathway.
NEMO-Binding Domain/IKKγ Inhibitory Peptide Alleviates Neuronal Pyroptosis in Spinal Cord Injury by Inhibiting ASMase-Induced Lysosome Membrane Permeabilization.
LNMAC Promotes Cervical Squamous Cell Carcinoma Lymphatic Metastasis via Epigenetic Regulation of FGF2-Induced Lymphangiogenesis.
S100A2 activation promotes interstitial fibrosis in kidneys by FoxO1-mediated epithelial-mesenchymal transition.
EIF4A3-mediated oncogenic circRNA hsa_circ_0001165 advances esophageal squamous cell carcinoma progression through the miR-381-3p/TNS3 pathway.
Hypoxia-induced DTL promotes the proliferation, metastasis, and sorafenib resistance of hepatocellular carcinoma through ubiquitin-mediated degradation of SLTM and subsequent Notch pathway activation.
Astaxanthin Alleviates Chronic Prostatitis via the ERK1/2 Signaling Pathway: Evidence from Network Pharmacology and Experimental Validation.
Integrative bioinformatics analysis for identifying the mitochondrial-related gene signature associated with immune infiltration in premature ovarian insufficiency.
Inhibition of HOXC11 by artesunate induces ferroptosis and suppresses ovarian cancer progression through transcriptional regulation of the PROM2/PI3K/AKT pathway.
Nme8 is essential for protection against chemotherapy drug cisplatin-induced male reproductive toxicity in mice.
Intracellular C5aR1 inhibits ferroptosis in glioblastoma through METTL3-dependent m6A methylation of GPX4.
YTHDF1-regulated ALOX5 in retinal pigment epithelial cells under hypoxia enhances VEGF expression and promotes viability, migration, and angiogenesis of vascular endothelial cells.
Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Methylation in Protein Stability and Interaction.
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.
Bile from the hemojuvelin-deficient mouse model of iron excess is enriched in iron and ferritin.
5-Hydroxymethylcytosine in circulating cell-free DNA as a potential diagnostic biomarker for SLE.
The transcription factor PPARA mediates SIRT1 regulation of NCOR1 to protect damaged heart cells.
miR-744-5p promotes T-cell differentiation via inhibiting STK11.
Human adipose and umbilical cord mesenchymal stem cell-derived extracellular vesicles mitigate photoaging via TIMP1/Notch1.
The RNA N6-methyladenosine demethylase FTO regulates ATG5 to inhibit malignant progression of uveal melanoma.
Filamin B knockdown impairs differentiation and function in mouse pre-osteoblasts via aberrant transcription and alternative splicing.
Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role.
Nuclear retention coupled with sequential polyadenylation dictates post-transcriptional m(6)A modification in the nucleus.
TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival.
Schistosoma japonicum infection-mediated downregulation of lncRNA Malat1 contributes to schistosomiasis hepatic fibrosis by the Malat1/miR-96/Smad7 pathway.
Mutation of Pseudomonas aeruginosa lasI/rhlI diminishes its cytotoxicity, oxidative stress, inflammation, and apoptosis on THP-1 macrophages.
Antimicrobial efficiency and cytocompatibility of resveratrol and naringin as chemical decontaminants on SLA surface.
Formononetin Mitigates Liver Fibrosis via Promoting Hepatic Stellate Cell Senescence and Inhibiting EZH2/YAP Axis.
ML385, an Nrf2 Inhibitor, Synergically Enhanced Celastrol Triggered Endoplasmic Reticulum Stress in Lung Cancer Cells.
HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway.
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
CircCSPP1 Competitively Binds miR-10a to Regulate BMP7 Expression and Affects the Proliferation of Dermal Papilla Cells.
The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms.
Sequential system based on ferritin delivery system and cell therapy for modulating the pathological microenvironment and promoting recovery.
Myrislignan ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
LncRNA MALAT1 regulates cigarette smoke induced airway inflammation by modulating miR-30a-5p/JNK signaling pathway.
SLC4A4 as a novel biomarker involved in immune system response and lung adenocarcinoma progression.
HIV Protein Nef Induces Cardiomyopathy Through Induction of Bcl2 and p21.
SETDB1 targeting SESN2 regulates mitochondrial damage and oxidative stress in renal ischemia-reperfusion injury.
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Mitochondrial MOF regulates energy metabolism in heart failure via ATP5B hyperacetylation.
Luteolin Protects against Vascular Calcification by Modulating SIRT1/CXCR4 Signaling Pathway and Promoting Autophagy.
Nuclear receptor 4A1 ameliorates UUO-induced renal fibrosis by inhibiting the PI3K/AKT pathway.
IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism.
Targeting NUF2 suppresses gastric cancer progression through G2/M phase arrest and apoptosis induction.
Sulforaphane Promotes Proliferation of Porcine Granulosa Cells via the H3K27ac-Mediated GDF8-ALK5-ERK Pathway.
The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals.
Exploring the Mechanism of Sempervirine Inhibiting Glioblastoma Invasion Based on Network Pharmacology and Bioinformatics.
Tumor Microenvironment-Responsive Biodegradable Nanomedicine for Self-Enhanced Synergistic Chemo-, Photothermal, and Chemodynamic Therapy.
Lactobacillus rhamnosus GG-derived extracellular vesicles promote wound healing via miR-21-5p-mediated re-epithelization and angiogenesis.
A novel biomimetic nanovesicle containing caffeic acid-coupled carbon quantum dots for the the treatment of Alzheimer's disease via nasal administration.
Platelet factors ameliorate thoracic aortic aneurysm and dissection by inhibiting the FGF-FGFR cascade activation in aortic-endothelial cell.
Divergent input patterns to the central lateral amygdala play a duet in fear memory formation.
Quercetin alleviates liver fibrosis via regulating glycolysis of liver sinusoidal endothelial cells and neutrophil infiltration.
GRASP55 Regulates Sorting and Maturation of the Lysosomal Enzyme β-Hexosaminidase A.
Expression study of Krabbe Disease GALC missense variants - Insights from quantification profiles of residual enzyme activity, secretion and psychosine levels.
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury.
Seneca Valley virus circumvents Gasdermin A-mediated inflammation by targeting the pore-formation domain for cleavage.
Micro RNA-175 Targets Claudin-1 to Inhibit Madin-Darby Canine Kidney Cell Adhesion.
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.
The combination of paeoniflorin and metformin synergistically inhibits the progression of liver fibrosis in mice.
The Role of Human Adiponectin Receptor 1 in 2-Ethylhexyl Diphenyl Phosphate Induced Lipid Metabolic Disruption.
Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma.
Human cytomegalovirus pUL135 protein affects endothelial cell function via CD2AP in Kawasaki disease.
ARNTL2 facilitates bladder cancer progression through potentiating ENO1-mediated glycolysis in a SLC31A1-independent and -dependent manner.
Nanoparticles target M2 macrophages to silence kallikrein-related peptidase 12 for the treatment of tuberculosis and drug-resistant tuberculosis.
FPR1 signaling aberrantly regulates S100A8/A9 production by CD14(+)FCN1(hi) macrophages and aggravates pulmonary pathology in severe COVID-19.
Neuronal BAG3 attenuates tau hyperphosphorylation, synaptic dysfunction, and cognitive deficits induced by traumatic brain injury via the regulation of autophagy-lysosome pathway.
Ursodeoxycholic Acid Platinum(IV) Conjugates as Antiproliferative and Antimetastatic Agents: Remodel the Tumor Microenvironment through Suppressing JAK2/STAT3 Signaling.
SMEK1 promotes clear cell renal cell carcinoma progression via EGFR tyrosine-kinase dependent pathway.
Vitexin Inhibits TNBC Progression and Metastasis by Modulating Macrophage Polarization Through EGFR Signaling.
SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8(+) T cell activation.
Chronic exposure to polystyrene microplastics induced LHR reduction and decreased testosterone levels through NF-κB pathway.
FBXL19 in endothelial cells protects the heart from influenza A infection by enhancing antiviral immunity and reducing cellular senescence programs.
The phosphorylation of Smad3 by CaMKIIγ leads to the hepatocyte pyroptosis under perfluorooctane sulfonate exposure.
Modulation of choline and lactate metabolism by basic fibroblast growth factor mitigates neuroinflammation in type 2 diabetes: Insights from (1)H-NMR metabolomics analysis.
Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways.
Induction of tau pathology and motor dysfunction in mice by urinary exosomes from progressive supranuclear palsy patients.
Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins.
KLF2 Inhibits Ferroptosis and Improves Mitochondrial Dysfunction in Chondrocyte Through SIRT1/GPX4 Signaling to Improve Osteoarthritis.
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
PPARγ-mediated amelioration of lipid metabolism abnormality by kaempferol.
Serum exosomal miRNA promote glioma progression by targeting SOS1 via abscopal effect of radiation.
Downregulation of C1R promotes hepatocellular carcinoma development by activating HIF-1α-regulated glycolysis.
Combined treatment with Aronia berry extract and oligomeric proanthocyanidins exhibit a synergistic anticancer efficacy through LMNB1-AKT signaling pathways in colorectal cancer.
Non-coding RNA alterations in occlusal disharmony-induced anxiety-like behaviour.
Sappanone A ameliorates acute lung injury through inhibiting the activation of the NF-κB signaling pathway.
CD73 alleviates osteoarthritis by maintaining anabolism and suppressing catabolism of chondrocytes extracellular matrix.
SUGT1 regulates the progression of ovarian cancer through the AKT/PI3K/mTOR signaling pathway.
MDM2 accelerated renal senescence via ubiquitination and degradation of HDAC1.
Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E-deficient mice.
CypA/TAF15/STAT5A/miR-514a-3p feedback loop drives ovarian cancer metastasis.
O-GlcNAcylation of circadian clock protein Bmal1 impairs cognitive function in diabetic mice.
PCPE-1, a brown adipose tissue-derived cytokine, promotes obesity-induced liver fibrosis.
OSGIN1 regulates PM(2.5)-induced fibrosis via mediating autophagy in an in vitro model of COPD.
LncRNA MBNL1-AS1 knockdown increases the sensitivity of hepatocellular carcinoma to tripterine by regulating miR-708-5p-mediated glycolysis.
Long non-coding RNA MALAT1 triggers ferroptosis via interaction with FUS to enhance ACSF2 mRNA stabilization in septic acute kidney injury.
Ferulic Acid Inhibits Arsenic-Induced Colon Injury by Improving Intestinal Barrier Function.
Geniposidic Acid Attenuates Chronic Tubulointerstitial Nephropathy Through Regulation of the NF-ƙB/Nrf2 Pathway Via Aryl Hydrocarbon Receptor Signaling.
Albumin-based co-loaded sonosensitizer and STING agonist nanodelivery system for enhanced sonodynamic and immune combination antitumor therapy.
LNP-mRNA vaccine prevents type 1 diabetes in non-obese diabetes mice.
Exosomal miR-129-2-3p promotes airway epithelial barrier disruption in PM(2.5)-aggravated asthma.
NLRP12 inhibits PRRSV-2 replication by promoting GP2a degradation via MARCH8.
NFκB dynamics-dependent epigenetic changes modulate inflammatory gene expression and induce cellular senescence.
Integration of pharmacochemistry, pharmacodynamics and metabolomics to reveal active ingredients and mechanism of Nan Bao detox capsule alleviating methamphetamine addiction.
Methacrylated hyaluronic acid/laponite photosensitive, sustained-release hydrogel loaded with bilobalide for enhancing random flap survival through mitigation of endoplasmic reticulum stress.
Ciclopirox platinum(IV) conjugates suppress tumors by promoting mitophagy and provoking immune responses.
CYR61/CCN1: A novel mediator of redox response in corneal stromal cells of keratoconus.
Mechanistic study of NUPR1 in bladder cancer development through transcriptional regulation of CCR2.
Novel intercellular spread mode of respiratory syncytial virus contributes to neutralization escape.
Novel deoxyhypusine synthase (DHPS) inhibitors target hypusination-induced vasculogenic mimicry (VM) against malignant melanoma.
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca(2+) and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy.
Mechanism of Gastrodin against neurotoxicity based on network pharmacology, molecular docking and experimental verification.
Oleocanthal mitigates CoCl(2)-induced oxidative damage and apoptosis via regulating MAPK pathway in human retinal pigment epithelial cells.
Simeprevir induces ferroptosis through β-TrCP/Nrf2/GPX4 axis in triple-negative breast cancer cells.
Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy.
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
6-Gingerol improves lipid metabolism disorders in skeletal muscle by regulating AdipoR1/AMPK signaling pathway.
Apelin regulates mitochondrial dynamics by inhibiting Mst1-JNK-Drp1 signaling pathway to reduce neuronal apoptosis after spinal cord injury.
Shh regulates M2 microglial polarization and fibrotic scar formation after ischemic stroke.
Alteration of N-glycosylation of CDON promotes H(2)O(2)-induced DNA damage in H9c2 cardiomyocytes.
Involvement of spinal NADPH oxidase 4 and endoplasmic reticulum stress in morphine-tolerant rats.
Immunoinhibitory effects of hypoxia-driven reprogramming of EGR1(hi) and EGR3 positive B cells in the nasopharyngeal carcinoma microenvironment.
Selenomethionine alleviates Aeromonas hydrophila-induced oxidative stress and ferroptosis via the Nrf2/HO1/GPX4 pathway in grass carp.
ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification.
Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats.
Ligustilide alleviates oxidative stress during renal ischemia-reperfusion injury through maintaining Sirt3-dependent mitochondrial homeostasis.
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Copper-Based Composites Nanoparticles Improve Triple-Negative Breast Cancer Treatment with Induction of Apoptosis-Cuproptosis and Immune Activation.
Dual-Barb Microneedle with JAK/STAT Inhibitor-Loaded Nanovesicles Encapsulation for Tendinopathy.
Mn(II)-Aloe-Emodin Nanoscale Coordination Polymer Enhances Ferroptosis by Synergistically Enhancing Reactive Oxygen Species Generation via the Nrf2-GPX4 Axis.
CaMKII Exacerbates Doxorubicin-Induced Cardiotoxicity by Promoting Ubiquitination Through USP10 Inhibition.
Erbin alleviates sepsis-induced cardiomyopathy by inhibiting RIPK1-dependent necroptosis through activating PKA/CREB pathway.
LncRNA H19 accelerates renal fibrosis by negatively regulating the let-7b-5p/TGF-βR1/COL1A1 axis.
Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1.
Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway.
LncRNA FAISL Inhibits Calpain 2-Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast Cancer.
A Multi-Functional Nanoadjuvant Coupling Manganese with Toll-Like 9 Agonist Stimulates Potent Innate and Adaptive Anti-Tumor Immunity.
Role of PI3K/AKT signaling pathway involved in self-renewing and maintaining biological properties of chicken primordial germ cells.
Host-specific SRSF7 regulates polymerase activity and replication of influenza A virus.
Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway.
Dapagliflozin targets SGLT2/SIRT1 signaling to attenuate the osteogenic transdifferentiation of vascular smooth muscle cells.
GPR30 Agonist G1 Mitigates Sepsis-Induced Cardiac Dysfunction by Inhibiting ACE2/c-FOS-Mediated Necroptosis in Female Mice.
N-acetylglucosaminyltransferase V drives colorectal cancer metastasis by facilitating ZO-1 ubiquitination and degradation.
NEK2 is a potential pan-cancer biomarker and immunotherapy target.
Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.
PTPN20 promotes metastasis through activating NF-κB signaling in triple-negative breast cancer.
The inhibitory effect of Hypericum japonicum on H9N2 avian influenza virus.
NSUN2 Promotes Head and Neck Squamous Cell Carcinoma Progression by Targeting EMT-Related Gene LAMC2 in an m(5)C-YBX1-Dependent Manner.
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
Reactive astrocytes promote tumor progression by up-regulating tumor protocadherin 1 expression in lung cancer brain metastasis.
Perinatal exposure to PBEB aggravates liver injury via macrophage-derived TWEAK in male adult offspring mice under western diet.
Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury.
Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy.
Development of oxidative stress- and ferroptosis-related prognostic signature in gastric cancer and identification of CDH19 as a novel biomarker.
LncRNA DDX11-AS1 promotes breast cancer progression by targeting the miR-30c-5p/MTDH axis.
Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation.
Distinct roles of Kif6 and Kif9 in mammalian ciliary trafficking and motility.
Establishment and validation of a prognostic model for idiopathic pulmonary fibrosis based on mitochondrial-related genes.
GABPA inhibits tumorigenesis in clear cell renal cell carcinoma by regulating ferroptosis through ACSL4.
SS31 alleviates LPS-induced acute lung injury by inhibiting inflammatory responses through the S100A8/NLRP3/GSDMD signaling pathway.
Proteomic analysis illustrates the potential involvement of dysregulated ribosome-related pathways and disrupted metabolism during retinoic acid-induced cleft palate development.
A hypoxia-activated and microenvironment-remodeling nanoplatform for multifunctional imaging and potentiated immunotherapy of cancer.
S100A7 orchestrates neutrophil chemotaxis and drives neutrophil extracellular traps (NETs) formation to facilitate lymph node metastasis in cervical cancer patients.
Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healing.
Unveiling Smyd-2's Role in Cytoplasmic Nrf-2 Sequestration and Ferroptosis Induction in Hippocampal Neurons After Cerebral Ischemia/Reperfusion.
Matrine protects against experimental autoimmune encephalomyelitis through modulating microglial ferroptosis.
Defects in CYB5A and CYB5B impact sterol-C4 oxidation in cholesterol biosynthesis and demonstrate regulatory roles of dimethyl sterols.
Screening and validation of key genes associated with osteoarthritis.
Therapeutic Potential of Oligo-Fucoidan in Mitigating Peritoneal Dialysis-Associated Fibrosis.
miR-122/NEGR1 axis contributes colorectal cancer liver metastasis by PI3K/AKT pathway and macrophage modulation.
Inhibition of lung tumorigenesis by transient reprogramming in cancer cells.
C-terminal tagging enhances the detection sensitivity of interlekin receptor type 1.
Perturbation of mammary epithelial cell apicobasal polarity by RHBDF1-facilitated nuclear translocation of PKCζ.
TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo study.
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
Capsaicin and Quercitrin Maintained Lipid Homeostasis of Hyperlipidemic Mice: Serum Metabolomics and Signaling Pathways.
Non-Sugar Sweetener Rubusoside Alleviates Lipid Metabolism Disorder In Vivo and In Vitro by Targeting PPARγ/α, Lgals3, and Mknk2.
Adipose stem cell exosomes, stimulated by pro-inflammatory factors, enhance immune evasion in triple-negative breast cancer by modulating the HDAC6/STAT3/PD-L1 pathway through the transporter UCHL1.
Mechanism of cold exposure delaying wound healing in mice.
Co-targeting TMEM16A with a novel monoclonal antibody and EGFR with Cetuximab inhibits the growth and metastasis of esophageal squamous cell carcinoma.
Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor.
Inhibition of PA28γ expression can alleviate osteoarthritis by inhibiting endoplasmic reticulum stress and promoting STAT3 phosphorylation.
Arginine methylation-dependent TRIM47 stability mediated by CARM1 promotes the metastasis of hepatocellular carcinoma.
Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma.
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Identifying genetic targets in clinical subtypes of Parkinson's disease for optimizing pharmacological treatment strategies.
ATP6V1C1, associated with the tumor microenvironment and mTORC1 signaling pathway, is a potential diagnostic, prognostic, and therapeutic biomarker for hepatocellular carcinoma.
Esketamine improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation.
Ankrd1 regulates endogenous cardiac regeneration in mice by modulating cyclin D1.
Dapagliflozin suppressed gastric cancer growth via regulating OTUD5 mediated YAP1 deubiquitination.
A novel mutation alters GNE bifunctional enzyme activity and leads to familial inherited GNE diseases.
CD248 interacts with ECM to promote hypertrophic scar formation and development.
Potential predictive value of immune-related genes FUCA1 and NCKAP1L for osteosarcoma metastasis.
YAP1 Inhibition Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer.
Trimethylamine Induced Chronic Kidney Injury by Activating the ZBP1-NLRP3 Inflammasome Pathway.
EHD1 promotes breast cancer metastasis through upregulating HIF2a expression via activating mTOR pathway.
Hippocampal cannabinoid type 2 receptor alleviates chronic neuropathic pain-induced cognitive impairment via microglial DUSP6 pathway in rats.
Supplemented Gegen Qinlian Decoction Formula attenuates podocyte mitochondrial fission and renal fibrosis in diabetic kidney disease by inhibiting TNF-α-mediated necroptosis, compared with empagliflozin.
Proteomic and lipidomic analysis of the mechanism underlying astragaloside IV in mitigating ferroptosis through hypoxia-inducible factor 1α/heme oxygenase 1 pathway in renal tubular epithelial cells in diabetic kidney disease.
MANF inhibits NLRP3 inflammasome activation by competitively binding to DDX3X in paraquat-stimulated alveolar macrophages.
Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation.
Exploring heparin's protective mechanism against AGEs induced endothelial injury.
Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F-53B Exposure: The Role of PKA Cytoplasmic Retention.
Inhibiting NF-κB inducing kinase improved the motor performance of ALS animal model.
IL-32 aggravates metabolic disturbance in human nucleus pulposus cells by activating FAT4-mediated Hippo/YAP signaling.
Manganese-mediated potentiation of antitumor immune responses by enhancing KLRG1(+) Macrophage function.
Focusing on non-responders to infliximab with ulcerative colitis, what can we do first and next?
Gal-1-mediated cytochrome p450 activation promotes fibroblast into myofibroblast differentiation in pulmonary fibrosis.
Total glucosides of Picrorhizae Rhizome alleviate non-alcoholic steatohepatitis (NASH) by specifically targeting acyl-CoA oxidase 1.
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Palladium-Mediated Bioorthogonal System for Prodrug Activation of N-Benzylbenzamide-Containing Tubulin Polymerization Inhibitors for the Treatment of Solid Tumors.
Age-related STING suppression in macrophages contributes to increased viral load during influenza a virus infection.
microRNA-637/661 ameliorate hypoxic-induced pulmonary arterial hypertension by targeting TRIM29 signaling pathway.
Periodontitis promotes tumor growth and immune evasion via PD-1/PD-L1.
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal Domain.
Nervonic acid improves depression like behaviors and demyelination of medial prefrontal cortex in chronic restraint stress mice.
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
PI3K p85α/HIF-1α accelerates the development of pulmonary arterial hypertension by regulating fatty acid uptake and mitophagy.
More powerful dysregulation of Helicobacter pylori East Asian-type CagA on intracellular signalings.
ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis.
SIRT1-Dependent Neuroprotection by Resveratrol in TOCP-Induced Spinal Cord Injury: Modulation of ER Stress and Autophagic Flux.
Role of Peptidyl Arginine Deiminase 4-Dependent Macrophage Extracellular Trap Formation in Type 1 Diabetes Pathogenesis.
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
The changes of tPA/PAI-1 system are associated with the ratio of BDNF/proBDNF in major depressive disorder and SSRIs antidepressant treatment.
Downregulation of heat shock protein 47 caused lysosomal dysfunction leading to excessive chondrocyte apoptosis.
Lanostane triterpenoids from Ganoderma calidophilum exhibit potent anti-tumor activity by inhibiting PTP1B.
A heterozygous SPRY4 variant identified in female infertility characterized by reduced oocyte potential and early embryonic arrest.
Establishment and characterization of a mouse model for studying kidney repair in diabetes.
Mode of action exploration for prostate epithelial cell injury caused by bisphenol A.
SKI-606, a Src inhibitor, ameliorates benzene-induced hematotoxicity via blocking ROS/Src kinase-mediated p38 and Akt signaling pathways.
Neuronostatin regulates neuronal function and energetic metabolism in Alzheimer's disease in a GPR107-dependent manner.
Loss of interferon regulatory factor-1 prevents lung fibrosis by upregulation of pon1 expression.
Ubiquitination of ATAD3A by TRIM25 exacerbates cerebral ischemia-reperfusion injury via regulating PINK1/Parkin signaling pathway-mediated mitophagy.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
The Elabela-APJ axis attenuates sepsis-induced myocardial dysfunction by reducing pyroptosis by balancing the formation and degradation of autophagosomes.
Ultrasound-mediated nanobubbles loaded with STAT6 siRNA inhibit TGF-β1-EMT axis in LUSC cells via overcoming the polarization of M2-TAMs.
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Fingolimod, a sphingosine-1-phosphate receptor modulator, prevents neonatal bronchopulmonary dysplasia and subsequent airway remodeling in a murine model.
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level.
Superoxide dismutase 2 scavenges ROS to promote osteogenic differentiation of human periodontal ligament stem cells by regulating Smad3 in alveolar bone-defective rats.
Androgens exacerbate hepatic triglyceride accumulation in rats with polycystic ovary syndrome by downregulating MTTP expression.
Study on the mechanism of arsenic-induced renal injury based on SWATH proteomics technology.
Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway.
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells.
Interleukin-22 Alleviates Caerulein-Induced Acute Pancreatitis by Activating AKT/mTOR Pathway.
Activation of hepatic acetyl-CoA carboxylase by S-nitrosylation in response to diet.
Neuronal CFL1 upregulation in head and neck squamous cell carcinoma enhances tumor-nerve crosstalk and promotes tumor growth.
p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
Identification of several African swine fever virus replication inhibitors by screening of a library of FDA-approved drugs.
Dihydroartemisinin, a potential PTGS1 inhibitor, potentiated cisplatin-induced cell death in non-small cell lung cancer through activating ROS-mediated multiple signaling pathways.
mTORC1 - TFEB pathway was involved in sodium arsenite induced lysosomal alteration, oxidative stress and genetic damage in BEAS-2B cells.
Salidroside Mediated the Nrf2/GPX4 Pathway to Attenuates Ferroptosis in Parkinson's Disease.
Inhibition of CK2 Diminishes Fibrotic Scar Formation and Improves Outcomes After Ischemic Stroke via Reducing BRD4 Phosphorylation.
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
Dihydroartemisinin eliminates senescent cells by promoting autophagy-dependent ferroptosis via AMPK/mTOR signaling pathway.
Histological study of telocytes in mice intrauterine adhesion model and their positive effect on mesenchymal stem cells in vitro.
Propane-2-sulfonic acid octadec-9-enyl-amide, a novel PPARα/γ dual agonist, attenuates molecular pathological alterations in learning memory in AD mice.
Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching.
Lidocaine inhibits migration of tenocytes by downregulating focal adhesion kinase and paxillin phosphorylation.
Enhancing therapeutic efficacy in breast cancer: a study on the combined cytotoxic effects of doxorubicin and MPC-3100.
LncRNA PFAR facilitates the proliferation and migration of papillary thyroid carcinoma by competitively binding to miR-15a.
Co-encapsulation of granzyme B and perforin in nanocapsules for tumour therapy: biomimicking immune cells.
Effect of GLIS1 on the Lymph Node Metastasis of Cervical Squamous Carcinoma Based on Transcriptome Analysis.
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress.
Radiotherapy upregulated immune checkpoints contribute to the development of second primary OSCC.
Hypoxia inducible factor-1α facilitates transmissible gastroenteritis virus replication by inhibiting type I and type III interferon production.
Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Expression of human dCTP pyrophosphatase 1 (DCTPP1) and its association with cisplatin resistance characteristics in ovarian cancer.
Improved therapeutic effects on vascular intimal hyperplasia by mesenchymal stem cells expressing MIR155HG that function as a ceRNA for microRNA-205.
Relationship between circadian rhythm-related genes and extracellular matrix: implications for sleep deprivation.
Effects of total saikosaponins on CYP3A4 and CYP1A2 in HepaRG cells.
Prognostic biomarker HIF1α and its correlation with immune infiltration in gliomas.
Nattokinase attenuates endothelial inflammation through the activation of SRF and THBS1.
Cardiac-specific overexpression of CREM-IbΔC-X via CRISPR/Cas9 in mice presents a new model of atrial cardiomyopathy with spontaneous atrial fibrillation.
NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway.
METTL14 affects UVB-induced human dermal fibroblasts photoaging via miR-100-3p biogenesis in an m(6)A-dependent manner.
Genetic and pharmacological modulation of lamin A farnesylation determines its function and turnover.
DDX20 positively regulates the interferon pathway to inhibit viral infection.
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy.
Near-Infrared Light-Driven Nanoparticles for Cancer Photoimmunotherapy by Synergizing Immune Cell Death and Epigenetic Regulation.
Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Caffeic acid alleviates skeletal muscle atrophy in 5/6 nephrectomy rats through the TLR4/MYD88/NF-kB pathway.
Trimethylamine-N-oxide aggravated the sympathetic excitation in D-galactose induced aging rats by down-regulating P2Y12 receptor in microglia.
Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.
Pilose antler extract promotes hair growth in androgenic alopecia mice by promoting the initial anagen phase.
Identification of CREB5 as a prognostic and immunotherapeutic biomarker in glioma through multi-omics pan-cancer analysis.
The circadian clock gene, BMAL1, promotes radiosensitization in nasopharyngeal carcinoma by inhibiting the epithelial-to-mesenchymal transition via the TGF-β1/Smads/Snail1 axis.
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Epidermal Stem Cell Derived Exosomes Alleviate Excessive Autophagy Induced Endothelial Cell Apoptosis by Delivering miR200b-3p to Diabetic Wounds.
SPP1 represents a therapeutic target that promotes the progression of oesophageal squamous cell carcinoma by driving M2 macrophage infiltration.
Paris polyphylla ethanol extract and polyphyllin I ameliorate adenomyosis by inhibiting epithelial-mesenchymal transition.
TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway.
Cerebral furin deficiency causes hydrocephalus in mice.
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
Deciphering the Therapeutic Role of Lactate in Combating Disuse-Induced Muscle Atrophy: An NMR-Based Metabolomic Study in Mice.
RRP8, associated with immune infiltration, is a prospective therapeutic target in hepatocellular carcinoma.
Expression and Purification of Recombinant Bowman-Birk Trypsin Inhibitor from Foxtail Millet Bran and Its Anticolorectal Cancer Effect In Vitro and In Vivo.
Association between NDUFS1 from urinary extracellular vesicles and decreased differential renal function in children with ureteropelvic junction obstruction.
Brucella Manipulates Host Cell Ferroptosis to Facilitate Its Intracellular Replication and Egress in RAW264.7 Macrophages.
Gingipain-carrying outer membrane vesicles from Porphyromonas gingivalis cause barrier dysfunction of Caco-2 cells by releasing gingipain into the cytosol.
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
FTH1 overexpression using a dCasRx translation enhancement system protects the kidney from calcium oxalate crystal-induced injury.
GJB3: a comprehensive biomarker in pan-cancer prognosis and immunotherapy prediction.
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Protective Effects of an Oligo-Fucoidan-Based Formula against Osteoarthritis Development via iNOS and COX-2 Suppression following Monosodium Iodoacetate Injection.
Irradiated microparticles suppress prostate cancer by tumor microenvironment reprogramming and ferroptosis.
Systemic LPS Administration Stimulates the Activation of Non-Neuronal Cells in an Experimental Model of Spinal Muscular Atrophy.
Decidual natural killer cells dysfunction is caused by IDO downregulation in dMDSCs with Toxoplasma gondii infection.
Dihydroartemisinin alleviates doxorubicin-induced cardiotoxicity and ferroptosis by activating Nrf2 and regulating autophagy.
Mitochondria transplantation alleviates cardiomyocytes apoptosis through inhibiting AMPKα-mTOR mediated excessive autophagy.
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability.
Exosome-derived circUPF2 enhances resistance to targeted therapy by redeploying ferroptosis sensitivity in hepatocellular carcinoma.
PD-1/PD-L1 axis is involved in the interaction between microglial polarization and glioma.
CD47, a novel YAP target gene, contributes to hepatic stellate cell activation and liver fibrosis induced by high-fat diet.
Patient tissue-derived FGFR4-variant and wild-type colorectal cancer organoid development and anticancer drug sensitivity testing.
CCR2 antagonist attenuates calcium oxalate-induced kidney oxidative stress and inflammation by regulating macrophage activation.
Transmembrane protein modulates seizure in epilepsy: evidence from temporal lobe epilepsy patients and mouse models.
Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy.
VDR is a potential prognostic biomarker and positively correlated with immune infiltration: a comprehensive pan-cancer analysis with experimental verification.
αO-Conotoxin GeXIVA[1,2] Suppresses In Vivo Tumor Growth of Triple-Negative Breast Cancer by Inhibiting AKT-mTOR, STAT3 and NF-κB Signaling Mediated Proliferation and Inducing Apoptosis.
Machine learning-based identification and immune characterization of ferroptosis-related molecular clusters in osteoarthritis and validation.
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.
USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation.
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Induce Fetal Wound Healing Features Revealed by Single-Cell RNA Sequencing.
Micropeptide AF127577.4-ORF hidden in a lncRNA diminishes glioblastoma cell proliferation via the modulation of ERK2/METTL3 interaction.
Effect of M0 macrophage-derived exosome miR-181d-5p targeting BCL-2 to regulate NLRP3/caspase-1/GSDMD pathway on human renal mesangial cells pyroptosis.
BDTX-189, a novel tyrosine kinase inhibitor, inhibits cell activity via ERK and AKT pathways in the EGFR C797S triple mutant cells.
α5-nAChR/ADAM10 signaling mediates nicotine-related cutaneous melanoma progression via STAT3 activation.
WTAP-mediated m(6)A modification of lncRNA Snhg1 improves myocardial ischemia-reperfusion injury via miR-361-5p/OPA1-dependent mitochondrial fusion.
A new prognostic model based on gamma-delta T cells for predicting the risk and aiding in the treatment of clear cell renal cell carcinoma.
Matrix stiffening promotes chondrocyte senescence and the osteoarthritis development through downregulating HDAC3.
Ursonic acid from medicinal herbs inhibits PRRSV replication through activation of the innate immune response by targeting the phosphatase PTPN1.
Xiaoyaosan promotes neurotransmitter transmission and alleviates CUMS-induced depression by regulating the expression of Oct1 and Oct3 in astrocytes of the prefrontal cortex.
Anti-papillary thyroid carcinoma effects of dioscorea bulbifera L. through ferroptosis and the PI3K/AKT pathway based on network pharmacology and experimental validation.
An integrated network pharmacology, molecular docking and experiment validation study to investigate the potential mechanism of Isobavachalcone in the treatment of osteoarthritis.
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
Respiratory Syncytial Virus Vaccine Design Using Structure-Based Machine-Learning Models.
Oral Administration of Deer Bone Collagen Peptide Can Enhance the Skin Hydration Ability and Antioxidant Ability of Aging Mice Induced by D-Gal, and Regulate the Synthesis and Degradation of Collagen.
Enhanced Efficacy against Drug-Resistant Tumors Enabled by Redox-Responsive Mesoporous-Silica-Nanoparticle-Supported Lipid Bilayers as Targeted Delivery Vehicles.
The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging.
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
AKAP8 promotes ovarian cancer progression and antagonizes PARP inhibitor sensitivity through regulating hnRNPUL1 transcription.
Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging.
Increased Thyroid DPP4 Expression Is Associated With Inflammatory Process in Patients With Hashimoto Thyroiditis.
Sequential glycosylations at the multibasic cleavage site of SARS-CoV-2 spike protein regulate viral activity.
Functional metabolomics reveals arsenic-induced inhibition of linoleic acid metabolism in mice kidney in drinking water.
Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects.
Sialyltransferase ST3GAL6 silencing reduces α2,3-sialylated glycans to regulate autophagy by decreasing HSPB8-BAG3 in the brain with hepatic encephalopathy.
TRIM25 predominately associates with anti-viral stress granules.
Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes.
Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3'UTR to decrease the expression of CD82.
Sialic acids as attachment factors in mosquitoes mediating Japanese encephalitis virus infection.
Inhibition of the RLR signaling pathway by SARS-CoV-2 ORF7b is mediated by MAVS and abrogated by ORF7b-homologous interfering peptide.
Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells.
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
The Rejuvenation and Functional Restoration of Aged Adipose Stem Cells by DUXAP10 Knockdown via the Regulation of the miR-214-3p/RASSF5 Axis.
The role of microRNA-142a in Toxoplasma gondii infection-induced downregulation of Foxp3: implications for adverse pregnancy outcomes.
Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis.
Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop.
Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles.
Deciphering metabolic heterogeneity in retinoblastoma unravels the role of monocarboxylate transporter 1 in tumor progression.
Integration of metabolomics and transcriptomics reveals that Da Chuanxiong Formula improves vascular cognitive impairment via ACSL4/GPX4 mediated ferroptosis.
Classical prescription Floris Sophorae Powder treat colorectal cancer by regulating KRAS/MEK-ERK signaling pathway.
Acod1/itaconate activates Nrf2 in pulmonary microvascular endothelial cells to protect against the obesity-induced pulmonary microvascular endotheliopathy.
Single-cell transcriptomic analysis of decidual immune cell landscape in the occurrence of adverse pregnancy outcomes induced by Toxoplasma gondii infection.
Identification of an Immunodominant B-Cell Epitope in African Swine Fever Virus p30 Protein and Evidence of p30 Antibody-Mediated Antibody Dependent Cellular Cytotoxicity.
Minimally invasive vagus nerve stimulation modulates mast cell degranulation via the microbiota-gut-brain axis to ameliorate blood-brain barrier and intestinal barrier damage following ischemic stroke.
LAMP1 controls CXCL10-CXCR3 axis mediated inflammatory regulation of macrophage polarization during inflammatory stimulation.
Cadmium exacerbates liver injury by remodeling ceramide metabolism: Multiomics and laboratory evidence.
Dihydroartemisinin is an inhibitor of trained immunity through Akt/mTOR/HIF1α signaling pathway.
Salidroside induces mitochondrial dysfunction and ferroptosis to inhibit melanoma progression through reactive oxygen species production.
Dibutyl phthalate exposure induced mitochondria-dependent ferroptosis by enhancing VDAC2 in zebrafish ZF4 cells.
Melatonin alleviates glyphosate-induced testosterone synthesis inhibition via targeting mitochondrial function in roosters.
Loss of KLF15 impairs endometrial receptivity by inhibiting EMT in endometriosis.
Salvianolic acid B attenuates diabetic nephropathy through alleviating ADORA2B, NALP3 in flammasome, and NFκB activity.
UCP2 overexpression activates SIRT3 to regulate oxidative stress and mitochondrial dynamics induced by myocardial injury.
Role of MAPKs in TGF-β1-induced maturation and mineralization in human osteoblast-like cells.
Integrative analyses of N6-methyladenosine-associated single-nucleotide polymorphisms (m6A-SNPs) identify tumor suppressor gene AK9 in lung cancer.
lncRNA UCA1 promotes tumor progression by targeting SMARCD3 in cervical cancer.
Genomic sequencing revealed recombination event between clade 1 and clade 2 occurs in circulating varicella-zoster virus in China.
NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica‑induced lung fibrosis.
Genome-scale CRISPR-Cas9 screen identifies PAICS as a therapeutic target for EGFR wild-type non-small cell lung cancer.
KIAA1549 promotes the development and chemoresistance of colorectal cancer by upregulating ERCC2.
Tropisetron attenuates neuroinflammation and chronic neuropathic pain via α7nAChR activation in the spinal cord in rats.
Cardiac-specific deletion of BRG1 ameliorates ventricular arrhythmia in mice with myocardial infarction.
Baicalein attenuates rotenone-induced SH-SY5Y cell apoptosis through binding to SUR1 and activating ATP-sensitive potassium channels.
NADP(+)-dependent isocitrate dehydrogenase as a novel target for altering carbon flux to lipid accumulation and enhancing antioxidant capacity in Tetradesmus obliquus.
Sevoflurane Suppresses Glioma Cell Proliferation, Migration, and Invasion Both In Vitro and In Vivo Partially Via Regulating KCNQ1OT1/miR-146b-5p/STC1 Axis.
Alginate microspheres encapsulating hox transcript antisense RNA siRNA regulate the Hedgehog-Gli1 pathway to alleviate epidermal growth factor receptor tyrosine kinase inhibitors resistance.
Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models.
LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1.
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
Mitochondrial-targeting and NIR-responsive Mn(3)O(4)@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis.
SESN1 functions as a new tumor suppressor gene via Toll-like receptor signaling pathway in neuroblastoma.
Mitochondrial protein CHCHD10 inhibits NDV replication and reduces pathological changes.
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Research on triamcinolone-loaded thermosensitive chitosan hydrogels for preventing esophageal stricture induced by endoscopic submucosal dissection.
Bi-functional KIT-PR1P peptides combine with VEGF to protect ischemic kidney in rats by targeting to Kim-1.
Osteopontin-driven partial epithelial-mesenchymal transition governs the development of middle ear cholesteatoma.
Lipoteichoic acid restrains macrophage senescence via β-catenin/FOXO1/REDD1 pathway in age-related osteoporosis.
HuR-positive stress granules: Potential targets for age-related osteoporosis.
Ethanol extract of Cyathulae Radix inhibits osteoclast differentiation and bone loss.
Targeting ZIP8 mediated ferroptosis as a novel strategy to protect against the retinal pigment epithelial degeneration.
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
Physical and social environmental enrichment alleviate ferroptosis and inflammation with inhibition of TLR4/MyD88/p38MAPK pathway in chronic cerebral hypoperfusion rats.
BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1.
Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA.
STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.
DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A(2) mediated lysosomal membrane permeabilization after spinal cord injury.
2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1, 4-Dione isolated from Averrhoa carambola L. root inhibits high glucose-induced EMT in HK-2 cells through targeting the regulation of miR-21-5p/Smad7 signaling pathway.
Ubiquitination of cytoplasmic HMGB1 by RNF186 regulates hepatic lipophagy in non-alcoholic fatty liver disease.
Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene.
NSUN2 promotes colorectal cancer progression by enhancing SKIL mRNA stabilization.
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
Enhancing Bone Regeneration through CDC20-Loaded ZIF-8 Nanoparticles Wrapped in Erythrocyte Membranes with Targeting Aptamer.
3D Printed Photothermal Scaffold Sandwiching Bacteria Inside and Outside Improves The Infected Microenvironment and Repairs Bone Defects.
Poliumoside protects against type 2 diabetes-related osteoporosis by suppressing ferroptosis via activation of the Nrf2/GPX4 pathway.
Gansui Banxia decoction modulates immune-inflammatory homeostasis to ameliorate malignant ascites in rats.
Potential of Lactobacillus plantarum A56 in relieving food allergy through immunoregulation, antioxidation, and reshaping intestinal microbiota.
Cypermethrin induces Sertoli cell apoptosis through endoplasmic reticulum-mitochondrial coupling involving IP3R1-GRP75-VDAC1.
Stiffness promotes cell migration, invasion, and invadopodia in nasopharyngeal carcinoma by regulating the WT-CTTN level.
DEAD-box helicase 1 inhibited CD8(+) T cell antitumor activity by inducing PD-L1 expression in hepatocellular carcinoma.
METTL3-mediated m(6)A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.
A comprehensive evaluation of circ_0065214/ miR-188-3p/GPNMB axis in breast cancer.
The impact of LncRNA-SOX2-OT/let-7c-3p/SKP2 Axis on head and neck squamous cell carcinoma progression: Insights from bioinformatics analysis and experimental validation.
Truncated PD1 Engineered Gas-Producing Extracellular Vesicles for Ultrasound Imaging and Subsequent Degradation of PDL1 in Tumor Cells.
Lentinan inhibits cell invasion via M2 polarization of tumor-associated macrophages and Wnt/β-catenin signaling in non-small cell lung cancer.
CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner.
Dysregulation and antimetastatic function of circLRIG1 modulated by miR-214-3p/LRIG1 axis in bladder carcinoma.
Spinosin inhibits activated hepatic stellate cell to attenuate liver fibrosis by targeting Nur77/ASK1/p38 MAPK signaling pathway.
Psychological stress induces hair regenerative disorders through corticotropin-releasing hormone-mediated autophagy inhibition.
Upregulation of TRPC1 protects against high glucose-induced HUVECs dysfunction by inhibiting oxidative stress.
Investigating the Impact of Dimer Interface Mutations on Norrin's Secretion and Norrin/β-Catenin Pathway Activation.
A high-affinity fluorescent probe for human uridine-disphosphate glucuronosyltransferase 1A9 function monitoring under environmental pollutant exposure.
Hub gene ELK3-mediated reprogramming lipid metabolism regulates phenotypic switching of pulmonary artery smooth muscle cells to develop pulmonary arterial hypertension induced by PM(2.5).
Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8(+)T cells.
CETSA-MS-based target profiling of anti-aging natural compound quercetin.
ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice.
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
N6-methyladenosine-modified CircPSMA7 enhances bladder cancer malignancy through the miR-128-3p/MAPK1 axis.
Candesartan upregulates angiotensin-converting enzyme 2 in kidneys of male animals by decreased ubiquitination.
RFX1 regulates foam cell formation and atherosclerosis by mediating CD36 expression.
MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer.
Activation of astrocytes by ANXA2-derived extracellular vesicles from lung cancer cells affects aggressiveness, immunotherapy response and microenvironment of lung cancer.
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx.
Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironment.
Dietary chenodeoxycholic acid attenuates high-fat diet-induced growth retardation, lipid accumulation and bile acid metabolism disorder in the liver of yellow catfish Pelteobagrus fulvidraco.
Riboflavin Attenuates Fluoride-Induced Testicular Injury via Interleukin 17A-Mediated Classical Pyroptosis.
Glutathione Induces Keap1 S-Glutathionylation and Mitigates Oscillating Glucose-Induced β-Cell Dysfunction by Activating Nrf2.
YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS.
Wnt5a/β-catenin-mediated epithelial-mesenchymal transition: a key driver of subretinal fibrosis in neovascular age-related macular degeneration.
Network pharmacology analysis and experimental validation to explore the mechanism of kaempferol in the treatment of osteoporosis.
Naoxinqing tablet protects against cerebral ischemic/reperfusion injury by regulating ampkα/NAMPT/SIRT1/PGC-1α pathway.
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
Air-Liquid Interface Microfluidic Monitoring Sensor Platform for Studying Autophagy Regulation after PM2.5 Exposure.
A Pilot Study on a Possible Mechanism behind Olfactory Dysfunction in Parkinson's Disease: The Association of TAAR1 Downregulation with Neuronal Loss and Inflammation along Olfactory Pathway.
TROP2 is highly expressed in triple-negative breast cancer CTCs and is a potential marker for epithelial mesenchymal CTCs.
Supplementation of Nicotinic Acid and Its Derivatives Up-Regulates Cellular NAD(+) Level Rather than Nicotinamide Derivatives in Cultured Normal Human Epidermal Keratinocytes.
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling.
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species.
NAP-seq reveals multiple classes of structured noncoding RNAs with regulatory functions.
Mechanistic Insights into the Inhibition of a Common CTLA-4 Gene Mutation in the Cytoplasmic Domain.
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Low-intensity pulsed ultrasound delays the progression of osteoarthritis by regulating the YAP-RIPK1-NF-κB axis and influencing autophagy.
Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway.
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
FTO-mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway.
Polystyrene microplastic-induced extracellular vesicles cause kidney-related effects in the crosstalk between tubular cells and fibroblasts.
Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA.
CircTBC1D22A inhibits the progression of colorectal cancer through autophagy regulated via miR-1825/ATG14 axis.
Minimally invasive delivery of human umbilical cord-derived mesenchymal stem cells by an injectable hydrogel via Diels-Alder click reaction for the treatment of intrauterine adhesions.
A pyrimidine metabolism-related signature for prognostic and immunotherapeutic response prediction in hepatocellular carcinoma by integrating analyses.
Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis.
FTO-mediated autophagy inhibition promotes non-small cell lung cancer progression by reducing the stability of SESN2 mRNA.
IDI1 inhibits the cGAS-Sting signaling pathway in hepatocellular carcinoma.
Pro-tumorigenic activity of PYCR1 in gastric cancer through regulating the PI3K/AKT signaling.
Discovery of Novel N-(Anthracen-9-ylmethyl) Benzamide Derivatives as ZNF207 Inhibitors Promising in Treating Glioma.
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
Transcriptome analysis of Edwardsiella piscicida during intracellular infection reveals excludons are involved with the activation of a mitochondrion-like energy generation program.
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway.
ATG9A as a potential diagnostic marker of intervertebral disc degeneration: Inferences from experiments and bioinformatics analysis incorporating sc-RNA-seq data.
Two novel angiotensin I-converting enzyme inhibitory peptides from garlic protein: In silico screening, stability, antihypertensive effects in vivo and underlying mechanisms.
Sphingosine kinase 1-specific inhibitor PF543 reduces goblet cell metaplasia of bronchial epithelium in an acute asthma model.
Veronica linariifolia subsp. dilatata ameliorates LPS-induced acute lung injury by attenuating endothelial cell barrier dysfunction via EGFR/Akt/ZO-1 pathway.
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Mode of action exploration of reproductive toxicity induced by bisphenol S using human normal ovarian epithelial cells through ERβ-MAPK signaling pathway.
PPP2R1B abolishes colorectal cancer liver metastasis and sensitizes Oxaliplatin by inhibiting MAPK/ERK signaling pathway.
miR-345-3p Modulates M1/M2 Macrophage Polarization to Inhibit Inflammation in Bone Infection via Targeting MAP3K1 and NF-κB Pathway.
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
Influenza A virus infection disrupts the function of syncytiotrophoblast cells and contributes to adverse pregnancy outcomes.
ID2 promotes tumor progression and metastasis in thyroid cancer.
Lentinan mitigates pemetrexed chemoresistance by the PI3K/Akt pathway in non-small cell lung cancer.
miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure.
Neuronal small extracellular vesicles carrying miR-181c-5p contribute to the pathogenesis of epilepsy by regulating the protein kinase C-δ/glutamate transporter-1 axis in astrocytes.
Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating BNIP3-Mediated mitochondrial dysfunction.
Albizzia chinensis (Osbeck) Merr extract YS ameliorates ethanol-induced acute gastric ulcer injury in rats by regulating NRF2 signaling pathway.
Norisoboldine, a Natural Alkaloid from Lindera aggregata (Sims) Kosterm, Promotes Osteogenic Differentiation via S6K1 Signaling Pathway and Prevents Bone Loss in OVX Mice.
MiR-5189-3p Suppresses cell Proliferation, Invasion and Migration Through Targeting EIF5A2 in Laryngeal Squamous Cell Carcinoma.
Environmental Enrichment Improves the Recognition Memory in Adult Mice Following Social Isolation via Downregulation of Kv4.2 Potassium Channels.
A Disintegrin and Metalloproteinase-8 Protects Against Erastin-Induced Neuronal Ferroptosis via Activating Nrf2/HO-1/FTH1 Signaling Pathway.
Acupuncture Alleviates Chronic Ischemic White Matter Injury in SHR Rats via JNK-NMDAR Circuit.
METTL3-mediated pre-miR-665/DLX3 m(6)A methylation facilitates the committed differentiation of stem cells from apical papilla.
Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade.
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes-associated HLA-B39 allotypes.
Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.
DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway.
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
FBXO22 is a potential therapeutic target for recurrent chondrosarcoma.
Quantitative systems pharmacology modeling of HER2-positive metastatic breast cancer for translational efficacy evaluation and combination assessment across therapeutic modalities.
High-dimensional deconstruction of ovarian cancer at single-cell precision reveals HEBP2 that reshape the TIME and drive carboplatin resistance.
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
Beclin 1 Haploinsufficiency Ameliorates High-Fat Diet-Induced Myocardial Injury via Inhibiting Alternative Mitophagy.
Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway.
The mechanism of action of myricetin against lung adenocarcinoma based on bioinformatics, in silico and in vitro experiments.
Circ_0027791 contributes to the growth and immune evasion of hepatocellular carcinoma via the miR-496/programmed cell death ligand 1 axis in an m6A-dependent manner.
Mice harboring the T316N variant in the GABA(A)R γ(2) subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway.
MARK1 regulates dendritic spine morphogenesis and cognitive functions in vivo.
PANoptosis subtypes predict prognosis and immune efficacy in gastric cancer.
CircMYBL1 suppressed acquired resistance to osimertinib in non-small-cell lung cancer.
Effect of continuous positive airway pressure treatment on Th17/Treg imbalance in patients with obstructive sleep apnea and a preliminary study on its mechanism.
SNORD99 promotes endometrial cancer development by inhibiting GSDMD-mediated pyroptosis through 2'-O-methylation modification.
ATF3 is involved in rSjP40-mediated inhibition of HSCs activation in Schistosoma japonicum-infected mice.
Atorvastatin causes developmental and behavioral toxicity in yellowstripe goby (Mugilogobius chulae) embryos/larvae via disrupting lipid metabolism and autophagy processes.
Bioinformatics analysis and experimental verification of NLRX1 as a prognostic factor for esophageal squamous cell carcinoma.
Metabolic reprogramming driven by METTL1-mediated tRNA m7G modification promotes acquired anlotinib resistance in oral squamous cell carcinoma.
Comprehensive analysis of ATP6V1s family member, ATP6V1C2, with prognostic and drug development values in colorectal cancer.
Anti-pancreatic cancer activity of cassane diterpenoids isolated from the seeds of Caesalpinia sappan mediated by autophagy activation via ROS/AMPK/mTORC1 pathway.
The chemerin-CMKLR1 axis in keratinocytes impairs innate host defense against cutaneous Staphylococcus aureus infection.
The therapeutic role of SSEA3(+) human umbilical cord blood mononuclear cells in ischemic stroke model.
METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer.
Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis.
EGFL6 promotes endometrial cancer cell migration and proliferation.
Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation.
Polysaccharides from Dendrobium officinale delay diabetic kidney disease interstitial fibrosis through LncRNA XIST/TGF-β1.
CREB1 Silencing Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis Through Reducing RPL9 Expression and Blocking NF-κB Signaling.
Pravastatin promotes type 2 diabetes vascular calcification through activating intestinal Bacteroides fragilis to induce macrophage M1 polarization.
Unraveling Key m(6)A Modification Regulators Signatures in Postmenopausal Osteoporosis through Bioinformatics and Experimental Verification.
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.
Carrimycin inhibits coronavirus replication by decreasing the efficiency of programmed -1 ribosomal frameshifting through directly binding to the RNA pseudoknot of viral frameshift-stimulatory element.
Fangchinoline induces antiviral response by suppressing STING degradation.
Solamargine improves the therapeutic efficacy of anti-PD-L1 in lung adenocarcinoma by inhibiting STAT1 activation.
Moracin D suppresses cell growth and induces apoptosis via targeting the XIAP/PARP1 axis in pancreatic cancer.
Celastrol induced the autophagy of spermatogonia cells contributed to tripterygium glycosides-related testicular injury.
Quantitative proteomic analysis of circulating exosomes reveals the mechanism by which Triptolide protects against collagen-induced arthritis.
Overexpression of macrophage migration inhibitory factor protects against pressure overload-induced cardiac hypertrophy through regulating the miR-29b-3p/HBP1 axis.
Mussel-inspired immunomodulatory and osteoinductive dual-functional hydroxyapatite nanoplatform for promoting bone regeneration.
Dang-Gui-Si-Ni decoction facilitates wound healing in diabetic foot ulcers by regulating expression of AGEs/RAGE/TGF-β/Smad2/3.
Comprehensive Urinary Proteome Profiling Analysis Identifies Diagnosis and Relapse Surveillance Biomarkers for Bladder Cancer.
Triple Blockade of Oncogenic RAS Signaling Using KRAS and MEK Inhibitors in Combination with Irradiation in Pancreatic Cancer.
M2 macrophage-derived exosomes promote angiogenesis and improve cardiac function after myocardial infarction.
Oridonin represses lung cancer cell proliferation and migration by modulating AFAP1-AS1/IGF2BP1.
GSNOR overexpression enhances CAR-T cell stemness and anti-tumor function by enforcing mitochondrial fitness.
Chlormequat Chloride Inhibits TM3 Leydig Cell Growth via Ferroptosis-Initiated Inflammation.
Ethnopharmacological study on Adenosma buchneroides Bonati inhibiting inflammation via the regulation of TLR4/MyD88/NF-κB signaling pathway.
HDAC1/2/3-mediated downregulation of neurogranin is involved in cognitive impairment in offspring exposed to maternal subclinical hypothyroidism.
Label-free Raman imaging for screening of anti-inflammatory function food.
Fraxinellone alleviates colitis-related intestinal fibrosis by blocking the circuit between PD-1(+) Th17 cells and fibroblasts.
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
The effect and mechanism of palmar ginseng in type 2 diabetic cognitive impairment.
Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches.
Inhibition of CC chemokine receptor 1 ameliorates osteoarthritis in mouse by activating PPAR-γ.
Interleukin-22 receptor 1-mediated stimulation of T-type Ca(2+) channels enhances sensory neuronal excitability through the tyrosine-protein kinase Lyn-dependent PKA pathway.
Sorcin Inhibits Mitochondrial Apoptosis by Interacting with STAT3 via NF-κB Pathway.
Oncogenic functions and therapeutic potentials of targeted inhibition of SMARCAL1 in small cell lung cancer.
Qixian granule inhibits ferroptosis in vascular endothelial cells by modulating TRPML1 in the lysosome to prevent postmenopausal atherosclerosis.
JinChan YiShen TongLuo Formula ameliorate mitochondrial dysfunction and apoptosis in diabetic nephropathy through the HIF-1α-PINK1-Parkin pathway.
NFIC mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to represses malignant phenotype of non-small cell lung cancer cells.
Oxidative stress-induced EGR1 upregulation promotes NR4A3-mediated nucleus pulposus cells apoptosis in intervertebral disc degeneration.
Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs.
Ameliorated Effects of Fucoidan on Dextran Sulfate Sodium-Induced Ulcerative Colitis and Accompanying Anxiety and Depressive Behaviors in Aged C57BL/6 Mice.
Impact of Abl2/Arg deficiency on anxiety and depressive behaviors in mice.
Targeted inhibition of DHODH is synergistic with BCL2 blockade in HGBCL with concurrent MYC and BCL2 rearrangement.
M(6)A demethylase FTO-stabilized exosomal circBRCA1 alleviates oxidative stress-induced granulosa cell damage via the miR-642a-5p/FOXO1 axis.
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
Succinate promotes pulmonary fibrosis through GPR91 and predicts death in idiopathic pulmonary fibrosis.
Intracellular magnetic hyperthermia reverses sorafenib resistance in hepatocellular carcinoma through its action on signaling pathways.
LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition.
Proangiogenic effect and underlying mechanism of holmium oxide nanoparticles: a new biomaterial for tissue engineering.
A prominent role of LncRNA H19 in H. pylori CagA induced DNA damage response and cell malignancy.
Reciprocal regulation between RACGAP1 and AR contributes to endocrine therapy resistance in prostate cancer.
Heparin-Functionalized Bioactive Glass to Harvest Endogenous Growth Factors for Pulp Regeneration.
Immune- and metabolism-related gene signature analysis uncovers the prognostic and immune microenvironments of hepatocellular carcinoma.
Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.
Activation of kappa opioid receptor suppresses post-traumatic osteoarthritis via sequestering STAT3 on the plasma membrane.
Chlorobenzoquinones Aggravate RSL3-Induced Ferroptosis in ROS-Dependent Manner.
A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Exposure to polystyrene nanoplastics induces hepatotoxicity involving NRF2-NLRP3 signaling pathway in mice.
Integrated component identification, network pharmacology, and experimental verification revealed mechanism of Dendrobium officinale Kimura et Migo against lung cancer.
CRISPR/Cas9-based genome-wide screening for metastasis ability identifies FCGR1A regulating the metastatic process of ovarian cancer by targeting LSP1.
New strategy to treat spinal cord injury: Nafamostat mesilate suppressed NLRP3-mediated pyroptosis during acute phase.
Study on the molecular mechanisms of Liuwei Dihuang decoction against aging-related cognitive impairment based on network pharmacology and experimental verification.
Oncogenic and immunological role of EDIL3 in human tumours: From pan-cancer analysis to validation in gastric cancer.
Qingfei mixture mitigates immunosuppression of tumor microenvironment in non-small cell lung cancer by blocking stat1/Ido1-mediated tryptophan-kynurenine pathway.
ANGPTL3 diminishes the resistance of ovarian cancer to paclitaxel by blocking the PI3K-AKT-mTOR signaling pathway.
Chlamydia trachomatis T3SS Effector CT622 Induces Proinflammatory Cytokines Through TLR2/TLR4-Mediated MAPK/NF-κB Pathways in THP-1 Cells.
LINC08148 promotes the caveola-mediated endocytosis of Zika virus through upregulating transcription of Src.
Transmissible gastroenteritis virus induces inflammatory responses via RIG-I/NF-κB/HIF-1α/glycolysis axis in intestinal organoids and in vivo.
Pseudolaric Acid B Targets CD147 to Selectively Kill Acute Myeloid Leukemia Cells.
ROS-responsive MSC-derived Exosome Mimetics Carrying MHY1485 Alleviate Renal Ischemia Reperfusion Injury through Multiple Mechanisms.
HNRNPA2B1 stabilizes NFATC3 levels to potentiate its combined actions with FOSL1 to mediate vasculogenic mimicry in GBM cells.
Ciprofol alleviates remifentanil-induced hyperalgesia by regulating α2GABAARs, NR2B, and P-CaMKIIα levels in the spinal cord and hippocampus.
16α-OHE1 alleviates hypoxia-induced inflammation and myocardial damage via the activation of β2-Adrenergic receptor.
Ultrasound Microbubble-Stimulated miR-145-5p Inhibits Malignant Behaviors of Breast Cancer Cells by Targeting ACTG1.
Exposure to nicotine regulates prostaglandin E2 secretion and autophagy of granulosa cells to retard follicular maturation in mammals.
Co-exposure to fluoride and sulfur dioxide induces abnormal enamel mineralization in rats via the FGF9-mediated MAPK signaling pathway.
ARID3A enhances chemoresistance of pancreatic cancer via inhibiting PTEN-induced ferroptosis.
O-GlcNAcylation regulates the stability of transferrin receptor (TFRC) to control the ferroptosis in hepatocellular carcinoma cells.
The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation.
Postbiotics Prepared Using Lactobacillus reuteri Ameliorates Ethanol-Induced Liver Injury by Regulating the FXR/SHP/SREBP-1c Axis.
Chidamide enhances T-cell-mediated anti-tumor immune function by inhibiting NOTCH1/NFATC1 signaling pathway in ABC-type diffuse large B-cell lymphoma.
SIRT3-Mediated Deacetylation of SDHA Rescues Mitochondrial Bioenergetics Contributing to Neuroprotection in Rotenone-Induced PD Models.
Inhibiting Caveolin-1-Related Akt/mTOR Signaling Pathway Protects Against N-methyl-D-Aspartate Receptor Activation-Mediated Dysfunction of Blood-Brain Barrier in vitro.
Targeting HMGCS1 restores chemotherapy sensitivity in acute myeloid leukemia.
Effects of tetrahedral DNA nanostructures on the treatment of osteoporosis.
Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.
Gingipains may be one of the key virulence factors of Porphyromonas gingivalis to impair cognition and enhance blood-brain barrier permeability: An animal study.
A novel LINC02321 promotes cell proliferation and decreases cisplatin sensitivity in bladder cancer by regulating RUVBL2.
Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.
Epstein-Barr virus causes vascular abnormalities in epithelial malignancies through upregulating ANXA3-HIF-1α-VEGF pathway.
Prenatal exposure to low-dose bisphenol A disrupts hippocampal DNA methylation and demethylation in male rat offspring.
TLQP-21 facilitates diabetic wound healing by inducing angiogenesis through alleviating high glucose-induced injuries on endothelial progenitor cells.
TFEB ameliorates DEHP-induced neurotoxicity by activating GAL3/TRIM16 axis dependent lysophagy and alleviating lysosomal dysfunction.
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway.
Exosomes derived from vMIP-II-Lamp2b gene-modified M2 cells provide neuroprotection by targeting the injured spinal cord, inhibiting chemokine signals and modulating microglia/macrophage polarization in mice.
Activation of Wnt signaling mitigates blood-brain barrier disruption by inhibiting vesicular transcytosis after traumatic brain injury in mice.
Spinal histamine H4 receptor mediates chronic pruritus via p-ERK in acetone-ether-water (AEW)-induced dry skin mice.
USP36 inhibits apoptosis by deubiquitinating cIAP1 and survivin in colorectal cancer cells.
SHED-exos promote saliva secretion by suppressing p-ERK1/2-mediated apoptosis in glandular cells.
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Ginkgolic acids induce liver injury in mice through cell cycle arrest and immune stress under specific condition.
Silibinin attenuates TGF-β2-induced fibrogenic changes in human trabecular meshwork cells by targeting JAK2/STAT3 and PI3K/AKT signaling pathways.
Enhanced breast cancer treatment using phototherapy and RNS therapy with macrophage membrane-coated liposomes.
6-Thioguanine inhibits severe fever with thrombocytopenia syndrome virus through suppression of EGR1.
Inonotus obliquus (Chaga) against HFD/STZ-induced glucolipid metabolism disorders and abnormal renal functions by regulating NOS-cGMP-PDE5 signaling pathway.
FUDNC1-dependent mitophagy ameliorate motor neuron death in an amyotrophic lateral sclerosis mouse model.
SH-Alb inhibits phenotype remodeling of pro-fibrotic macrophage to attenuate liver fibrosis through SIRT3-SOD2 axis.
Astaxanthin alleviates fibromyalgia pain and depression via NLRP3 inflammasome inhibition.
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
LncRNA ZFPM2-AS1 promotes phyllodes tumor progression by binding to CDC42 and inhibiting STAT1 activation.
LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.
Baicalin reduces chronic stress-induced breast cancer metastasis via directly targeting β2-adrenergic receptor.
MCM8 promotes gastric cancer progression through RPS15A and predicts poor prognosis.
The dual role of 20(S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis.
Essential oil from Cinnamomum cassia Presl bark regulates macrophage polarization and ameliorates lipopolysaccharide-induced acute lung injury through TLR4/MyD88/NF-κB pathway.
Ginsenoside Rg5 inhibits glioblastoma by activating ferroptosis via NR3C1/HSPB1/NCOA4.
Celastrol mediates CAV1 to attenuate pro-tumorigenic effects of senescent cells.
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism.
Resveratrol regulates Thoc5 to improve maternal immune activation-induced autism-like behaviors in adult mouse offspring.
Bone morphogenetic protein 4 derived from the cerebrospinal fluid in patients with postherpetic neuralgia induces allodynia via the crosstalk between microglia and astrocyte.
Upregulated miR-374a-5p drives psoriasis pathogenesis through WIF1 downregulation and Wnt5a/NF-κB activation.
Microglial uptake of hADSCs-Exo mitigates neuroinflammation in ICH.
Brain Metastasis from EGFR-Mutated Non-Small Cell Lung Cancer: Secretion of IL11 from Astrocytes Up-Regulates PDL1 and Promotes Immune Escape.
The HSP90AA1 gene is involved in heat stress responses and its functional genetic polymorphisms are associated with heat tolerance in Holstein cows.
PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells.
Mitochondria-Targeted Natural Antioxidant Nanosystem for Diabetic Vascular Calcification Therapy.
Uric acid-lowering effect of harpagoside and its protective effect against hyperuricemia-induced renal injury in mice.
CALU promotes lung adenocarcinoma progression by enhancing cell proliferation, migration and invasion.
The Use of Polysaccharide AOP30 from the Rhizome of Alpinia officinarum Hance to Alleviate Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction and Inflammation via the TLR4/NfκB Signaling Pathway in Caco-2 Cell Monolayers.
Tangeretin Enhances Muscle Endurance and Aerobic Metabolism in Mice via Targeting AdipoR1 to Increase Oxidative Myofibers.
Eg5 UFMylation promotes spindle organization during mitosis.
Systematic analysis of TREM2 and its carcinogenesis in pancreatic cancer.
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Identification and experimental verification of immune-related hub genes in intervertebral disc degeneration.
Upregulation of LncRNA UCA1 promotes cardiomyocyte proliferation by inhibiting the miR-128/SUZ12/P27 pathway.
Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus.
Baicalin attenuates PD-1/PD-L1 axis-induced immunosuppression in piglets challenged with Glaesserella parasuis by inhibiting the PI3K/Akt/mTOR and RAS/MEK/ERK signalling pathways.
CHIP-mediated ubiquitin degradation of BCAT1 regulates glioma cell proliferation and temozolomide sensitivity.
N6-Methyladenosine enhances the translation of ENO1 to promote the progression of bladder cancer by inhibiting PCNA ubiquitination.
Repurposing GnRH-A as a Near-Infrared Fluorescent Probe for Diagnosis and Surgical Navigation of Breast Cancer Tumors and Metastases.
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication.
Deciphering the Effects of the PYCR Family on Cell Function, Prognostic Value, Immune Infiltration in ccRCC and Pan-Cancer.
Dihydrotanshinone I targets ESR1 to induce DNA double-strand breaks and proliferation inhibition in hepatocellular carcinoma.
Molecular mechanism of Chang Shen Hua volatile oil modulating brain cAMP-PKA-CREB pathway to improve depression-like behavior in rats.
Icariside II modulates pulmonary fibrosis via PI3K/Akt/β-catenin pathway inhibition of M2 macrophage program.
Salvianolic acid B protects against UVB-induced skin aging via activation of NRF2.
Effect of luteolin on glioblastoma's immune microenvironment and tumor growth suppression.
SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration.
Stress-induced TDP-43 nuclear condensation causes splicing loss of function and STMN2 depletion.
Enhanced therapeutic impact of Shikonin-encapsulated exosomes in the inhibition of colorectal cancer progression.
Empagliflozin protects against heart failure with preserved ejection fraction partly by inhibiting the senescence-associated STAT1-STING axis.
Effect of Bioactive Black Phosphorus Nanomaterials on Cancer-Associated Fibroblast Heterogeneity in Pancreatic Cancer.
Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma.
Alpha 1,3 N-Acetylgalactosaminyl Transferase (GTA) Impairs Invasion Potential of Trophoblast Cells in Preeclampsia.
Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway.
Acceleration of bone repairation by BMSCs overexpressing NGF combined with NSA and allograft bone scaffolds.
ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.
PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function.
Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling.
H3K27ac acts as a molecular switch for doxorubicin-induced activation of cardiotoxic genes.
Interior decorative volatile organic compounds exposure induces sleep disorders through aberrant branched chain amino acid transaminase 2 mediated glutamatergic signaling resulting from a neuroinflammatory cascade.
Paraquat disrupts KIF5A-mediated axonal mitochondrial transport in midbrain neurons and its antagonism by melatonin.
Dysregulation of hepatic one-carbon metabolism in classical homocystinuria: Implications of redox-sensitive DHFR repression and tetrahydrofolate depletion for pathogenesis and treatment.
Bmal1 regulates female reproduction in mice via the hypothalamic-pituitary-ovarian axis.
Aqueous extract of Epimedium sagittatum (Sieb. et Zucc.) Maxim. induces liver injury in mice via pyroptosis.
Paeonia lactiflora Pall. ameliorates acetaminophen-induced oxidative stress and apoptosis via inhibiting the PKC-ERK pathway.
Perfluorooctane sulfonate induces ferroptosis-dependent non-alcoholic steatohepatitis via autophagy-MCU-caused mitochondrial calcium overload and MCU-ACSL4 interaction.
The common pathogenesis of nodular goiter in both sexes: An exploration into gene expression and signaling pathways.
Integrating network pharmacology and experimental models to investigate the efficacy and mechanism of Tiansha mixture on xerosis.
LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway.
Nuclear alpha-synuclein accelerates cell senescence and neurodegeneration.
Therapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis.
RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway.
Genome-scale exon perturbation screens uncover exons critical for cell fitness.
Butyrate induces higher host transcriptional changes to inhibit porcine epidemic diarrhea virus strain CV777 infection in porcine intestine epithelial cells.
Cerebral Endothelial CXCR2 Promotes Neutrophil Transmigration into Central Nervous System in LPS-Induced Septic Encephalopathy.
The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.
Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC.
Circular RNA CircVmn2r1 Acts as a miR-223-3p Sponge to Promote Kidney Aging by Regulating NLRP3 Expression in Mice.
PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3.
Se-methylselenocysteine inhibits the progression of non-small cell lung cancer via ROS-mediated NF-κB signaling pathway.
O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis.
TBX5 pathogenic variant in a patient with congenital heart defect and tracheal stenosis.
FGF-18 Protects the Injured Spinal cord in mice by Suppressing Pyroptosis and Promoting Autophagy via the AKT-mTOR-TRPML1 axis.
Hantaan virus inhibits type I interferon response by targeting RLR signaling pathways through TRIM25.
The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study.
Fish oil omega-3 Fatty Acids Alleviate Postoperative delirium-like Behavior in aged mice by Attenuating Neuroinflammation and Oxidative Stress.
NMNATs expression inhibition mediated NAD(+) deficiency plays a critical role in doxorubicin-induced hepatotoxicity in mice.
Icariin rescues developmental BPA exposure induced spatial memory deficits in rats.
The lack of homology domain and leucine rich repeat protein phosphatase 2 ameliorates visual impairment in rats with diabetic retinopathy through regulation of the AKT-GSK-3β-Nrf2 signal cascade.
Long Non-Coding RNA H19 Leads to Upregulation of γ-Globin Gene Expression during Erythroid Differentiation.
Autocrine motility factor receptor promotes the malignancy of glioblastoma by regulating cell migration and invasion.
Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis.
Amplifying T cell-mediated antitumor immune responses in nonsmall cell lung cancer through photodynamic therapy and anti-PD1.
NADase CD38 is a key determinant of ovarian aging.
Role of PLC/IP(3) /IP(3) R axis in excess molybdenum exposure induced apoptosis in duck renal tubular epithelial cells.
CircNEK6 promotes the progression of pancreatic ductal adenocarcinoma through targeting miR-503/CCND1 axis.
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Multi-omics Analysis Identifies Hypoxia Subtypes and S100A2 as an Immunosuppressive Factor in Cervical Cancer.
FOXA2 activates HIF2α expression to promote tumor progression and is regulated by the E3 ubiquitin ligase VHL in renal cell carcinoma.
Exosomal miR-23a-3p derived from human umbilical cord mesenchymal stem cells promotes remyelination in central nervous system demyelinating diseases by targeting Tbr1/Wnt pathway.
MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Integrative analysis of cuproptosis-associated genes for predicting immunotherapy response in single-cell and multi-cohort studies.
Engineering of targeting antioxidant polypeptide nanopolyplexes for the treatment of acute lung injury.
Arginine-methylated c-Myc affects mitochondrial mitophagy in mouse acute kidney injury via Slc25a24.
Carrier-free nanodrug targeting glucose metabolism for enhanced rheumatoid arthritis treatment.
Self-assembled and dynamic bond crosslinked herb-polysaccharide hydrogel with anti-inflammation and pro-angiogenesis effects for burn wound healing.
YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes.
LAFEM: A Scoring Model to Evaluate Functional Landscape of Lysine Acetylome.
Photobiomodulation Facilitates Rat Cutaneous Wound Healing by Promoting Epidermal Stem Cells and Hair Follicle Stem Cells Proliferation.
CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Integrating multi-level interactive network and in vivo/vitro studies to explore the protective mechanism of Ampelopsis grossedentata in hyperuricemia.
Shen Qi Wan ameliorates nephritis in chronic kidney disease via AQP1 and DEFB1 regulation.
Inhibition of cGAS-STING pathway by stress granules after activation of M2 macrophages by human mesenchymal stem cells against drug induced liver injury.
Discovery of Taurocholic Acid Sodium Hydrate as a Novel Repurposing Drug for Intervertebral Disc Degeneration by Targeting MAPK3.
High glucose levels delay the senescence of stem cells from human exfoliated deciduous teeth by suppressing autophagy.
IL-22-Induced Ubiquitin-Specific Protease 15 Promotes Proliferation and Inflammation of Keratinocytes through Stabilization of Squamous Cell Carcinoma Antigen 2.
Mast Cells Initiate Type 2 Inflammation through Tryptase Released by MRGPRX2/MRGPRB2 Activation in Atopic Dermatitis.
Green synthesis and anti-tumor efficacy via inducing pyroptosis of novel 1H-benzo[e]indole-2(3H)-one spirocyclic derivatives.
LncRNA BCRT1 depletion suppresses cervical cancer cell growth via sponging miR-432-5p/CCR7 axis.
Grape seed-derived procyanidin inhibits glyphosate-induced hepatocyte ferroptosis via enhancing crosstalk between Nrf2 and FGF12.
Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis.
CircPHKB decreases the sensitivity of liver cancer cells to sorafenib via miR-1234-3p/CYP2W1 axis.
CircBRD7 attenuates tumor growth and metastasis in nasopharyngeal carcinoma via epigenetic activation of its host gene.
Hydro-Sensitive, In Situ Ultrafast Physical Self-Gelatinizing, and Red Blood Cells Strengthened Hemostatic Adhesive Powder with Antibiosis and Immunoregulation for Wound Repair.
Uncovering the mechanism of Naoxintong capsule against hypertension based on network analysis and in vitro experiments.
Study of hispidulin in the treatment of uric acid nephropathy based on NF-κB signaling pathway.
Necroptosis involved in sevoflurane-induced cognitive dysfunction in aged mice by activating NMDA receptors increasing intracellular calcium.
Sestrin 2 protects human lens epithelial cells from oxidative stress and apoptosis induced by hydrogen peroxide by regulating the mTOR/Nrf2 pathway.
Chinese Herbal Compound Xiaoliu Pingyi Recipe Inhibits the Growth of Lung Adenocarcinoma by Regulating the Tumor Vascular Microenvironment.
Systematic Characterization of DNA Methyltransferases Family in Tumor Progression and Antitumor Immunity.
A Comprehensive Prognostic Model for Colon Adenocarcinoma Depending on Nuclear-Mitochondrial-Related Genes.
Intestinal deguelin drives resistance to acetaminophen-induced hepatotoxicity in female mice.
Visualization of the Ferroptosis in Atherosclerotic Plaques with Nanoprobe Engineered by Macrophage Cell Membranes.
ZNFX1 promotes AMPK-mediated autophagy against Mycobacterium tuberculosis by stabilizing Prkaa2 mRNA.
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Danggui-Shaoyao-San (DSS) ameliorates the progression of osteoarthritis via suppressing the NF-κB signaling pathway: an in vitro and in vivo study combined with bioinformatics analysis.
Serine/threonine kinase 36 induced epithelial-mesenchymal transition promotes docetaxel resistance in prostate cancer.
EPYC functions as a novel prognostic biomarker for pancreatic cancer.
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton.
ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis.
Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1.
miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy.
Phlorizin, a novel caloric restriction mimetic, stimulates hypoxia and protects cardiomyocytes through activating autophagy via modulating the Hif-1α/Bnip3 axis in sepsis-induced myocardial dysfunction.
Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress.
WNTA5-mediated miR-374a-5p regulates vascular smooth muscle cell phenotype transformation and M1 macrophage polarization impacting intracranial aneurysm progression.
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Synbiotic Combination between Lactobacillus paracasei VL8 and Mannan-Oligosaccharide Repairs the Intestinal Barrier in the Dextran Sulfate Sodium-Induced Colitis Model by Regulating the Intestinal Stem Cell Niche.
TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance.
GRK5 promoted renal fibrosis via HDAC5/Smad3 signaling pathway.
MicroRNA miR-181d-5p regulates the MAPK signaling pathway by targeting mitogen-activated protein kinase 8 (MAPK8) to improve lupus nephritis.
Erchen decoction alleviates the progression of NAFLD by inhibiting lipid accumulation and iron overload through Caveolin-1 signaling.
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Modified Shoutai Pill inhibited ferroptosis to alleviate recurrent pregnancy loss.
Norepinephrine protects against cochlear outer hair cell damage and noise-induced hearing loss via α(2A)-adrenergic receptor.
A Self-Homing and Traceable Cardiac Patch Leveraging Ferumoxytol for Spatiotemporal Therapeutic Delivery.
PPIP5K2 Facilitates Proliferation and Metastasis of Non-Small Lung Cancer (NSCLC) through AKT Signaling Pathway.
Identification of cuproptosis-related molecular classification and characteristic genes in ulcerative colitis.
Single-cell transcriptomics enable the characterization of local extension in retinoblastoma.
Preclinical Repurposing of Sitagliptin as a Drug Candidate for Colorectal Cancer by Targeting CD24/CTNNB1/SOX4-Centered Signaling Hub.
Attenuation of PI3K-Akt-mTOR Pathway to Reduce Cancer Stemness on Chemoresistant Lung Cancer Cells by Shikonin and Synergy with BEZ235 Inhibitor.
Period circadian regulator 2-mediated steroid hormone synthesis by regulating transcription of steroidogenic acute regulatory protein in porcine granulosa cells.
PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury.
Network pharmacology and in vitro experimental verification unveil glycyrrhizin from glycyrrhiza glabra alleviates acute pancreatitis via modulation of MAPK and STAT3 signaling pathways.
Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway.
Malvidin promotes PGC-1α/Nrf2 signaling to attenuate the inflammatory response and restore mitochondrial activity in septic acute kidney injury.
LncRNA Gm28382 promotes lipogenesis by interacting with miR-326-3p to regulate ChREBP signaling pathway in NAFLD.
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
The protective effect of Ergolide in osteoarthritis: In vitro and in vivo studies.
Regulation of tumor metastasis and CD8(+) T cells infiltration by circRNF216/miR-576-5p/ZC3H12C axis in colorectal cancer.
RUNX1 targeting AKT3 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS induced ARDS.
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer.
Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasms.
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Identification of BANF1 as a novel prognostic biomarker in gastric cancer and validation via in-vitro and in-vivo experiments.
Targeting the NAT10/NPM1 axis abrogates PD-L1 expression and improves the response to immune checkpoint blockade therapy.
Discovery from Hypericum elatoides and synthesis of hyperelanitriles as α-aminopropionitrile-containing polycyclic polyprenylated acylphloroglucinols.
Heterogeneous Expression Patterns of the Minichromosome Maintenance Complex Members in Retinoblastoma Unveil Its Clinical Significance.
CCT2 prevented β-catenin proteasomal degradation to sustain cancer stem cell traits and promote tumor progression in epithelial ovarian cancer.
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding.
Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury.
Diallyl trisulfide inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via modulating gut microbiota and the PPARγ/NF-κB pathway.
Aging-Associated ALKBH5-m(6)A Modification Exacerbates Doxorubicin-Induced Cardiomyocyte Apoptosis Via AT-Rich Interaction Domain 2.
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.
IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects.
Osteocyte mitochondria inhibit tumor development via STING-dependent antitumor immunity.
Protective effect of low-intensity pulsed ultrasound on immune checkpoint inhibitor-related myocarditis via fine-tuning CD4(+) T-cell differentiation.
Uncovering the Therapeutic Potential of Phosphocreatine in Diabetic Retinopathy: Mitigating Mitochondrial Dysfunction and Apoptosis via JAK2/STAT3 Signaling Pathway.
Neutrophil extracellular trap-related mechanisms in acne vulgaris inspire a novel treatment strategy with adipose-derived stem cells.
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma.
17β-Estradiol inhibits hydrogen peroxide-induced senescence and apoptosis in human umbilical vein endothelial cells by regulating the THBS1/TGF-β/Smad axis.
ALKBH5 mediates silica particles-induced pulmonary inflammation through increased m(6)A modification of Slamf7 and autophagy dysfunction.
Smyd1: Implications for novel approaches in rhabdomyosarcoma therapy.
Loganin protects against myocardial ischemia-reperfusion injury by modulating oxidative stress and cellular apoptosis via activation of JAK2/STAT3 signaling.
Response of lipid metabolism, energy supply, and cell fate in yellowstripe goby (Mugilogobius chulae) exposed to environmentally relevant concentrations atorvastatin.
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Design, synthesis and biological evaluation of biaryl amide derivatives against SARS-CoV-2 with dual-target mechanism.
Mechanism of action of Shaoyao-Gancao decoction in relieving chronic inflammatory pain via Sema3G protein regulation in the dorsal root ganglion.
Novel molecular classification and prognosis of papillary renal cell carcinoma based on a large-scale CRISPR-Cas9 screening and machine learning.
ALKBH5 is a prognostic factor and promotes the angiogenesis of glioblastoma.
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
The anoikis-related gene signature predicts survival and correlates with immune infiltration in osteosarcoma.
The miR-19a/Cylindromatosis Axis Regulates Pituitary Adenoma Bone Invasion by Promoting Osteoclast Differentiation.
Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response.
Amyloid aggregates induced by the p53-R280T mutation lead to loss of p53 function in nasopharyngeal carcinoma.
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin.
Qinzhizhudan formula dampens inflammation in microglia polarization of vascular dementia rats by blocking MyD88/NF-κB signaling pathway: Through integrating network pharmacology and experimental validation.
Synergistic cerium oxide nanozymes: targeting DNA damage and alleviating tumor hypoxia for improved NSCLC radiotherapy efficiency.
GDF11 mediates H(2)S to prevent chronic stress-induced cognitive impairment by reducing hippocampal NLRP3/caspase-1-dependent pyroptosis.
Lycium barbarum polysaccharides attenuate oxidative stress and mitochondrial toxicity induced by mixed plasticizers in HepG2 cells through activation of Nrf2.
Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology.
Targeting HIF-1α alleviates the inflammatory responses and rebuilds the CD4(+) T cell subsets balance in the experimental autoimmune myasthenia gravis inflammation model via regulating cellular and humoral immunity.
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Nitro-oleic acid ameliorates erectile dysfunction in a streptozotocin-induced rat model of diabetes by inhibiting oxidative stress and apoptosis and activating the NO/cGMP pathway.
Neuronal pyroptosis mediated by STAT3 in early brain injury after subarachnoid hemorrhage.
Inhibition of SOCS3 signaling in the nucleus tractus solitarii and retrotrapezoid nucleus alleviates hypoventilation in diet-induced obese male mice.
Hydrogen sulfide attenuates atherosclerosis induced by low shear stress by sulfhydrylating endothelium NFIL3 to restrain MEST mediated endothelial mesenchymal transformation.
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions.
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
ACE2 activation alleviates sepsis-induced cardiomyopathy by promoting MasR-Sirt1-mediated mitochondrial biogenesis.
PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma.
7-Dehydrocholesterol dictates ferroptosis sensitivity.
Rho GTPase-activating protein 1 promotes hepatocellular carcinoma progression via modulation by CircPIP5K1A/MiR-101-3p.
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy.
Reticulon 3 regulates sphingosine-1-phosphate synthesis in endothelial cells to control blood pressure.
IRF4 Participates in Pulmonary Fibrosis Induced by Silica Particles through Regulating Macrophage Polarization and Fibroblast Activation.
Synergistic antitumor efficacy of gemcitabine and cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via Sp1-SAT1-polyamine metabolism pathway.
hPMSCs Regulate the Level of TNF-α and IL-10 in Th1 Cells and Improve Hepatic Injury in a GVHD Mouse Model via CD73/ADO/Fyn/Nrf2 Axis.
Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway.
C-C Motif Chemokine 2 Regulates Macrophage Polarization and Contributes to Myocardial Infarction Healing.
Activation of autophagy promotes the inhibitory effect of curcumin analog EF-24 against MDA-MB-231 cancer cells.
Immune Response Gene-1 [IRG1]/itaconate protect against multi-organ injury via inhibiting gasdermin D-mediated pyroptosis and inflammatory response.
Ketone bodies promote epididymal white adipose expansion to alleviate liver steatosis in response to a ketogenic diet.
Piperine improves levodopa availability in the 6-OHDA-lesioned rat model of Parkinson's disease by suppressing gut bacterial tyrosine decarboxylase.
Electroacupuncture pretreatment preserves telomerase reverse transcriptase function and alleviates postoperative cognitive dysfunction by suppressing oxidative stress and neuroinflammation in aged mice.
Roles of lncLingo2 and its derived miR-876-5p in the acquisition of opioid reinforcement.
Oncogenic and immunological roles of RACGAP1 in pan-cancer and its potential value in nasopharyngeal carcinoma.
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
Exosome-delivered miR-410-3p reverses epithelial-mesenchymal transition, migration and invasion of trophoblasts in spontaneous abortion.
Alleviating 3-MCPD-induced male reproductive toxicity: Mechanistic insights and resveratrol intervention.
In vitro and in vivo immunomodulatory activity of acetylated polysaccharides from Cyclocarya paliurus leaves.
Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation.
Trichinella spiralis cathepsin B bound and degraded host's intestinal type I collagen.
m5C modification of LINC00324 promotes angiogenesis in glioma through CBX3/VEGFR2 pathway.
KIF4A functions as a diagnostic and prognostic biomarker and regulates tumor immune microenvironment in skin cutaneous melanoma.
KBTBD2 promotes proliferation and migration of gastric cancer via activating EGFR signaling pathway.
Disrupted HSF1 regulation in normal and exceptional brain aging.
AGK2 pre-treatment protects against thioacetamide-induced acute liver failure via regulating the MFN2-PERK axis and ferroptosis signaling pathway.
In vitro and in vivo biological evaluation of Lappaconitine derivatives as potential anti-inflammatory agents.
MMP14(high) macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis.
Paxillin/HDAC6 regulates microtubule acetylation to promote directional migration of keratinocytes driven by electric fields.
Pan-cancer analysis of PLAU indicates its potential prognostic value and correlation with neutrophil infiltration in BLCA.
Sodium butyrate alleviates lead-induced neuroinflammation and improves cognitive and memory impairment through the ACSS2/H3K9ac/BDNF pathway.
Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway.
Periplaneta americana extract promotes hard palate mucosal wound healing via the PI3K/AKT signaling pathway in male mice.
Reduced Bioactive Microbial Products (Pathogen-Associated Molecular Patterns) Contribute to Dysregulated Immune Responses and Impaired Healing in Infected Wounds in Mice with Diabetes.
Penicimides A and B, two novel diels-alder [4 + 2] cycloaddition ergosteroids from Penicillium herquei.
Tanshinone IIA ameliorates energy metabolism dysfunction of pulmonary fibrosis using (13)C metabolic flux analysis.
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Assessing the mitochondrial safety profile of the molnupiravir active metabolite, β-d-N4-hydroxycytidine (NHC), in the physiologically relevant HepaRG model.
Palmatine ameliorated lipopolysaccharide-induced sepsis-associated encephalopathy mice by regulating the microbiota-gut-brain axis.
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation.
Fucoidan alleviated dextran sulfate sodium-induced ulcerative colitis with improved intestinal barrier, reshaped gut microbiota composition, and promoted autophagy in male C57BL/6 mice.
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer.
Rosuvastatin Enhances Lymphangiogenesis after Myocardial Infarction by Regulating the miRNAs/Vascular Endothelial Growth Factor Receptor 3 (miRNAs/VEGFR3) Pathway.
Multi-omics sequencing revealed endostar combined with cisplatin treated non small cell lung cancer via anti-angiogenesis.
An Esterase-Responsive SLC7A11 shRNA Delivery System Induced Ferroptosis and Suppressed Hepatocellular Carcinoma Progression.
Demyelination in the medial prefrontal cortex by withdrawal from chronic nicotine causes impaired cognitive memory.
METTL14 enhances the m6A modification level of lncRNA MSTRG.292666.16 to promote the progression of non-small cell lung cancer.
Dapagliflozin improves podocytes injury in diabetic nephropathy via regulating cholesterol balance through KLF5 targeting the ABCA1 signalling pathway.
The role of extracellular vesicle fusion with target cells in triggering systemic inflammation.
Trimethylamine N-Oxide Improves Exercise Performance by Reducing Oxidative Stress through Activation of the Nrf2 Signaling Pathway.
Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice.
Minocycline alleviates LPS-induced cognitive dysfunction in mice by inhibiting the NLRP3/caspase-1 pathway.
Cediranib ameliorates portal hypertensive syndrome via inhibition of VEGFR-2 signaling in cirrhotic rats.
Berberine inhibits NLRP3 inflammasome activation by regulating mTOR/mtROS axis to alleviate diabetic cardiomyopathy.
Adelmidrol ameliorates liver ischemia-reperfusion injury through activating Nrf2 signaling pathway.
Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation.
Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth.
Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.
Effects of exosomes derived from platelet-rich plasma on osteogenic differentiation of dental pulp stem cells.
Identification and validation of STAT4 as a prognostic biomarker in acute myeloid leukemia.
Deciphering a crucial dimeric interface governing Norrin dimerization and the pathogenesis of familial exudative vitreoretinopathy.
Comprehensive analysis of ovarian granulosa cell proteomics and phosphoproteomics in PCOS patients without insulin resistance.
Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma.
Akkermansia muciniphila Is Beneficial to a Mouse Model of Parkinson's Disease, via Alleviated Neuroinflammation and Promoted Neurogenesis, with Involvement of SCFAs.
The diagnostic, prognostic, drug sensitivity and ceRNA internet of PPP4R1 in liver hepatocellular carcinoma (LIHC).
Elevated SLC7A2 expression is associated with an abnormal neuroinflammatory response and nitrosative stress in Huntington's disease.
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation.
DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target.
TBC1D23 mediates Golgi-specific LKB1 signaling.
ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1.
EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells.
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling.
The P124A mutation of SRP14 alters its migration on SDS-PAGE without impacting its function.
Fisetin suppresses chondrocyte senescence and attenuates osteoarthritis progression by targeting sirtuin 6.
Ferritinophagy-mediated ferroptosis of spermatogonia is involved in busulfan-induced oligospermia in the mice.
DPPA2/4 Promote the Pluripotency and Proliferation of Bovine Extended Pluripotent Stem Cells by Upregulating the PI3K/AKT/GSK3β/β-Catenin Signaling Pathway.
Hsa_circ_0005397 promotes hepatocellular carcinoma progression through EIF4A3.
Lysine Demethylase 4A is a Centrosome Associated Protein Required for Centrosome Integrity and Genomic Stability.
In Vitro Ferroptotic and Antitumor Effect of Free or Liposome-Encapsulated Artesunate in Papillary Thyroid Cancer Cells.
Hsa_circ_0007990 promotes breast cancer growth via inhibiting YBX1 protein degradation to activate E2F1 transcription.
Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway.
Transcriptomics analysis revealed that TAZ regulates the proliferation of KIRC cells through mitophagy.
In Vitro Insights into the Role of 7,8-Epoxy-11-Sinulariolide Acetate Isolated from Soft Coral Sinularia siaesensis in the Potential Attenuation of Inflammation and Osteoclastogenesis.
5'-Cytimidine Monophosphate Ameliorates H(2)O(2)-Induced Muscular Atrophy in C2C12 Myotubes by Activating IRS-1/Akt/S6K Pathway.
Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins.
Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice.
Dendrobium officinale Polysaccharides as a Natural Functional Component for Acetic-Acid-Induced Gastric Ulcers in Rats.
Expanding the Genetic Code of Xenopus laevis Embryos.
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa.
G-protein-coupled estrogen receptor 1 promotes peritoneal metastasis of gastric cancer through nicotinamide adenine dinucleotide kinase 1-mediated redox modulation.
Protein 4.1R regulates M1 macrophages polarization via glycolysis, alleviating sepsis-induced liver injury in mice.
The cGAS-STING pathway promotes the development of preeclampsia by upregulating autophagy: Mechanisms and implications.
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
Characterization and verification of CAF-relevant prognostic gene signature to aid therapy in bladder cancer.
Puerarin Ameliorated PCOS through Preventing Mitochondrial Dysfunction Dependent on the Maintenance of Intracellular Calcium Homeostasis.
Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.
The involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells.
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
Identification of BMAL1-Regulated circadian genes in mouse liver and their potential association with hepatocellular carcinoma: Gys2 and Upp2 as promising candidates.
FOXM1 promote the growth and metastasis of uveal melanoma cells by regulating CDK2 expression.
ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling.
Pharmacological effects and mechanism of Maxing Shigan decoction in the treatment of Pseudomonas aeruginosa pneumonia.
Insights into the inhibition of stomach cancer MKN45 cell growth by Poria cocos ethanol-soluble extract based on MAPK/PI3K signaling pathways and components cell fishing.
AR/RKIP pathway mediates the inhibitory effects of icariin on renal fibrosis and endothelial-to-mesenchymal transition in type 2 diabetic nephropathy.
Huangqi Jiuni decoction prevents acute kidney injury induced by severe burns by inhibiting activation of the TNF/NF-κB pathway.
Counteracting Age-Related Netrin-1 Signaling Insufficiency Ameliorates Endothelial Cell Senescence and Angiogenesis Impairment.
DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Systematic pan-cancer analysis of RNF186 with potential implications in progression and prognosis in human cancer.
A study on the role of Taxifolin in inducing apoptosis of pancreatic cancer cells: screening results using weighted gene co-expression network analysis.
Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130a-3p/long-chain acyl-CoA synthetase 1 axis.
Different effects of low- and high-density lipoproteins in egg yolk on lipid metabolism of mouse: Role of phospholipids-to-cholesterol intake ratio.
5-oxoETE promote thrombosis in antiphospholipid syndrome by triggering NETs formation through PLC/PKC/ERK pathway.
ROR2 promotes cell cycle progression and cell proliferation through the PI3K/AKT signaling pathway in gastric cancer.
Circ-RNF111 Promotes Proliferation of Ovarian Cancer Cell SKOV-3 by Targeting the MiR-556-5p/CCND1 Axis.
Metformin Protects Against Acute Kidney Injury Induced by Lipopolysaccharide via Up-Regulating the MCPIP1/SIRT1 Pathway.
Shenqi Fuzheng injection restores the sensitivity to gefitinib in non-small cell lung cancer by inhibiting the IL-22/STAT3/AKT pathway.
Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents.
Cai's herbal tea enhances mitochondrial autophagy of type 1 diabetic mellitus β cells through the AMPK/mTOR pathway and alleviates inflammatory response.
Runx2 Suppresses Astrocyte Activation and Astroglial Scar Formation After Spinal Cord Injury in Mice.
Neuroprotective Effect of a Multistrain Probiotic Mixture in SOD1(G93A) Mice by Reducing SOD1 Aggregation and Targeting the Microbiota-Gut-Brain Axis.
Long non-coding RNA SUN2-AS1 acts as a negative regulator of ISGs transcription to promote flavivirus infection.
Pseudorabies virus UL13 primes inflammatory response through downregulating heat shock factor 1.
Mechanism of Resveratrol on LPS/ATP-induced pyroptosis and inflammatory response in HT29 cells.
Effects of MMP2 and its inhibitor TIMP2 on DNA damage, apoptosis and senescence of human lens epithelial cells induced by oxidative stress.
Analysis and identification of ferroptosis-related diagnostic markers in rheumatoid arthritis.
Exploring the roles and therapeutic implications of melatonin-mediated KLF6 in the development of intracranial aneurysm.
M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling.
Bleomycin induces endothelial cell pyroptosis and regulates fibrosis by activating the NLRP3/caspase-1/GSDMD pathway: a possible mechanism contributing to the sclerotherapy of venous malformations.
Insulin-Like Growth Factor-Binding Protein 5 Promotes the Cell Proliferation and Osteogenic Potential of Dental Pulp Stem Cells Dependent on Its Nuclear Localisation Sequence.
Bisphenol A disrupts the neuronal F-actin cytoskeleton by activating the RhoA/ROCK/LIMK pathway in Neuro-2a cells.
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
Protein arginine methyltransferase 5 confers the resistance of triple-negative breast cancer to nanoparticle albumin-bound paclitaxel by enhancing autophagy through the dimethylation of ULK1.
Hyperactivation of p53 contributes to mitotic catastrophe in podocytes through regulation of the Wee1/CDK1/cyclin B1 axis.
Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy.
Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial-mesenchymal transition.
Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway.
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes.
Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect.
Vascular wall microenvironment: Endothelial cells original exosomes mediated melatonin-suppressed vascular calcification and vascular ageing in a m6A methylation dependent manner.
MiR-19b-3p inhibits cell viability and proliferation and promotes apoptosis by targeting IGF1 in KGN cells.
MST1R Gene Variants Predispose Individuals to Tetralogy of Fallot.
Mediation of circ_0007142 on miR-128-3p/S100A14 pathway to stimulate the progression of cervical cancer.
Epigenetic Regulation of RNF135 by LSD1 Promotes Stemness Maintenance and Brain Metastasis in Lung Adenocarcinoma.
Increased UBD Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o-methoxy phenyl group as potential agents against gastric cancer.
Genetic deletion of the apoptosis associated speck like protein containing a card in LysM(+) macrophages attenuates spinal cord injury by regulating M1/M2 polarization through ASC-dependent inflammasome signaling axis.
Esculin Alleviates Osteoarthritis Progression Through the Sirt1/NF-κB Pathway.
Engineering of phosphatidylserine-targeting ROS-responsive polymeric prodrug for the repair of ischemia-reperfusion-induced acute kidney injury.
NIR-Actuated Ferroptosis Nanomotor for Enhanced Tumor Penetration and Therapy.
A cisplatin and disulphiram co-loaded inclusion complex overcomes drug resistance by inhibiting cancer cell stemness in non-small cell lung cancer.
H(2)Se-evolving bio-heterojunctions promote cutaneous regeneration in infected wounds by inhibiting excessive cellular senescence.
Spatiotemporal release of non-nucleotide STING agonist and AKT inhibitor from implantable 3D-printed scaffold for amplified cancer immunotherapy.
VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats.
Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway.
Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus.
Biodegradable exosome-engineered hydrogels for the prevention of peritoneal adhesions via anti-oxidation and anti-inflammation.
Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation.
Targeted regulation of autophagy using sorafenib-loaded biomineralization nanoenzyme for enhanced photodynamic therapy of hepatoma.
Injectable decellularized Wharton's jelly hydrogel containing CD56(+) umbilical cord mesenchymal stem cell-derived exosomes for meniscus tear healing and cartilage protection.
NR1D1 activation alleviates inflammatory response through inhibition of IL-6 expression in bovine endometrial epithelial cells.
Structure elucidation and molecular mechanism of an immunomodulatory polysaccharide from Nostoc commune.
DNA ligase III mediates deoxynivalenol exposure-induced DNA damage in intestinal epithelial cells by regulating oxidative stress and interaction with PCNA.
Porcine reproductive and respiratory syndrome virus activates lipid synthesis through a ROS-dependent AKT/PCK1/INSIG/SREBPs axis.
Aryl Hydrocarbon Receptor Alleviates Hepatic Fibrosis by Inducing Hepatic Stellate Cell Ferroptosis.
Intestinal epithelial vitamin D receptor defense against inflammatory bowel disease via regulating microfold cells.
Single-cell m(6)A profiling in the mouse brain uncovers cell type-specific RNA methylomes and age-dependent differential methylation.
Regulation of LAMTOR1 by oxidative stress in retinal pigment epithelium: Implications for age-related macular degeneration pathogenesis.
Critical role of apoptosis in MeCP2-mediated epithelial-mesenchymal transition of ARPE-19 cells.
A rapid and versatile reverse genetic approach and visualization animal models for emerging zoonotic pseudorabies virus.
Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-x(L), display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity.
Comprehensive gene set enrichment and variation analyses identify SUV39H1 as a potential prognostic biomarker for glioblastoma immunorelevance.
Hydrogel and Microgel Collaboration for Spatiotemporal Delivery of Biofactors to Awaken Nucleus Pulposus-Derived Stem Cells for Endogenous Repair of Disc.
The time-dependent expression of FPR2 and ANXA1 in murine deep vein thrombosis model and its relation to thrombus age.
Role of GLCCI1 in inhibiting PI3K-induced NLRP3 inflammasome activation in asthma.
Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway.
Activation of spleen tyrosine kinase (SYK) contributes to neuronal pyroptosis and cognitive impairment in diabetic mice via the NLRP3/Caspase-1/GSDMD signaling pathway.
Lithospermic acid inhibits dengue virus infection through binding with envelope proteins.
Testosterone-Induced H3K27 Deacetylation Participates in Granulosa Cell Proliferation Suppression and Pathogenesis of Polycystic Ovary Syndrome.
ANRIL upregulates TGFBR1 to promote idiopathic pulmonary fibrosis in TGF-β1-treated lung fibroblasts via sequestering let-7d-5p.
An artificial peptide inhibits autophagy through calcineurin-TFEB pathway.
Long non-coding RNA Snhg15 promotes preosteoblast proliferation by interacting with and stabilizing nucleolin.
TRPV4-β-catenin axis is a novel therapeutic target for dry skin-induced chronic itch.
TMAO induces pyroptosis of vascular endothelial cells and atherosclerosis in ApoE(-/-) mice via MBOAT2-mediated endoplasmic reticulum stress.
Molecular mechanism through which Tripterygium hypoglaucum (Lévl.) Hutch alleviates psoriasis.
Inhibition of JNK/STAT3/NF-KB pathway-mediated migration and clonal formation of lung adenocarcinoma A549 cells by daphnetin.
Knockdown of PIK3R6 impedes the onset and advancement of clear cell renal cell carcinoma.
BMP5 promotes trophoblast functions upon N-glycosylation via the BMP5-SMAD1/5 signaling pathway in preeclampsia.
ARID1A recruits GATA2 to regulate the senescence of trophoblast cells under high-glucose condition.
Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stress.
Discovery and optimization of novel 4-morpholinothieno[3,2-d]pyrimidine derivatives as potent BET inhibitors for cancer therapy.
Design, green synthesis, and anti-glutamate damage screening of chalcone derivatives with spiro-heterocyclic structures as potential anti-ischemic brain and eye damage agents.
Design, synthesis, and biological evaluation of novel HPK1 inhibitors possessing 3-cyano-quinoline moiety.
Discovery of novel 5-phenyl-1H-pyrrole-2-carboxylic acids as Keap1-Nrf2 inhibitors for acute lung injury treatment.
Altingia chinensis petroleum ether extract suppresses NSCLC via induction of apoptosis, attenuation of EMT, and downregulation of PI3K/Akt pathway.
Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway.
Yi-Fei-San-Jie Chinese medicine formula reverses immune escape by regulating deoxycholic acid metabolism to inhibit TGR5/STAT3/PD-L1 axis in lung cancer.
Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition.
Nrf2-dependent hepatoprotective effect of ellagic acid in titanium dioxide nanoparticles-induced liver injury.
Obacunone improves dihydrotestosterone-induced androgen alopecia by inhibiting androgen receptor dimerization.
Single-cell RNA transcriptomics reveals Du-Zhong-Wan promotes osteoporotic fracture healing via YAP/β-catenin/VEGF axis in BMSCs.
Hepatic miR-363 promotes nonalcoholic fatty liver disease by suppressing INSIG1.
Tribbles pseudokinase 3 promotes enterovirus A71 infection via dual mechanisms.
PYGB targeted by androgen receptor contributes to tumor progression and metabolic reprogramming in esophageal squamous carcinoma.
GALNT14-mediated O-glycosylation drives lung adenocarcinoma progression by reducing endogenous reactive oxygen species generation.
Unraveling the biological functions of UCEC: Insights from a prognostic signature model.
Discovery of Balasubramide Derivative with Tissue-Specific Anti-Inflammatory Activity Against Acute Lung Injury by Targeting VDAC1.
The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR-99a/mTOR-Mediated Autophagy and Apoptosis.
Transcriptomics-Based Liquid Biopsy for Early Detection of Recurrence in Locally Advanced Gastric Cancer.
Selenium nanoparticles affect chicken offspring's intestinal health better than other selenium sources.
Up-regulated Lnc BTU promotes the production of duck plague virus DNA polymerase and inhibits the activation of JAK-STAT pathway to facilitate duck plague virus replication.
Conditional ablation of MCU exacerbated cardiac pathology in a genetic arrhythmic model of CPVT.
Isoechinulin B, a natural product from Antarctic fungus, attenuates acute liver injury by inhibiting excessive cell adhesion.
RTA408 alleviates lipopolysaccharide-induced acute lung injury via inhibiting Bach1-mediated ferroptosis.
Simvastatin induces ferroptosis and activates anti-tumor immunity to sensitize anti-PD-1 immunotherapy in microsatellite stable gastric cancer.
CD39 inhibitor (POM-1) enhances radiosensitivity of esophageal squamous cell carcinoma (ESCC) cells by promoting apoptosis through the Bax/Bcl-2/Caspase 9/Caspase 3 pathway.
Melatonin prevents glyphosate-induced hepatic lipid accumulation in roosters via activating Nrf2 pathway.
Interleukin(IL)-37 attenuates isoproterenol (ISO)-induced cardiac hypertrophy by suppressing JAK2/STAT3-signaling associated inflammation and oxidative stress.
Nuciferine ameliorates osteoarthritis: An in vitro and in vivo study.
Identification of a nomogram predicting overall survival based on ADAP2-related apoptosis genes in gliomas.
MNSFβ promotes LPS-induced TNFα expression by increasing the localization of RC3H1 to stress granules, and the interfering peptide HEPN2 reduces TNFα production by disrupting the MNSFβ-RC3H1 interaction in macrophages.
A synergistic effect of triptolide and curcumin on rheumatoid arthritis by improving cell proliferation and inducing cell apoptosis via inhibition of the IL-17/NF-κB signaling pathway.
RNA Binding of GAPDH Controls Transcript Stability and Protein Translation in Acute Myeloid Leukemia.
Single-cell RNA sequencing analysis reveals potential key prognostic markers in hepatocellular carcinoma.
Milk fat globule-epidermal growth factor 8 exerts anti-osteoarthritis effects by inhibiting apoptosis and inducing autophagy in mouse chondrocytes.
Omentin-1 ameliorates pulmonary arterial hypertension by inhibiting endoplasmic reticulum stress through AMPKα signaling.
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial-mesenchymal transition.
DNAJB4/HLJ1 deficiency sensitizes diethylnitrosamine-induced hepatocarcinogenesis with peritumoral STAT3 activation.
SPDEF ameliorates UUO-induced renal fibrosis by transcriptional activation of NR4A1.
Transcriptional landscape and predictive potential of long noncoding RNAs in peritoneal recurrence of gastric cancer.
HMGCS2 and AMACR as potential targets linking mitochondrial dysfunction and ulcerative colitis.
Bone marrow mesenchymal stem cells modulate miR-202-3p to suppress neuronal apoptosis following spinal cord injury through autophagy activation via the AMPK, MAPK, and PI3K/AKT/mTOR signaling pathway.
Identifying novel aging-related diagnostic and prognostic models and aging-targeted drugs for sepsis patients.
Intervention effect of regulating GABA-A receptor activity on the formation of experimental abdominal aortic aneurysm in rats.
N7-methyladenosine-induced SLC7A7 serves as a prognostic biomarker in pan-cancer and promotes CRC progression in colorectal cancer.
Discovery of SILA-123 as a Highly Potent FLT3 Inhibitor for the Treatment of Acute Myeloid Leukemia with Various FLT3 Mutations.
USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc.
GANT61 surmounts drug resistance of ADR by upregulating lysosome activities and reducing BCL2 expression in HL-60/ADR cells.
The Pathogenic Role of Expanded CD8⁺CD28(null) Angiogenic T Cells in ANCA-Associated Vasculitis.
Notoginsenoside R1-Protocatechuic aldehyde reduces vascular inflammation and calcification through increasing the release of nitric oxide to inhibit TGFβR1-YAP/TAZ pathway in vascular smooth muscle cells.
Acetyl-11-keto-β-boswellia acid attenuates Ti particle-induced osteoblastic oxidative stress and osteolysis through the Foxo3 signaling pathway.
Nicotinamide adenine dinucleotide phosphate alleviates intestinal ischemia/reperfusion injury via Nrf2/HO-1 pathway.
Comprehensive multi-omics analysis of the prognostic value and immune signature of NCF2 in pan-cancer and its relationship with acute myeloid leukemia.
Neutrophil extracellular traps induce barrier dysfunction in DSS-induced ulcerative colitis via the cGAS-STING pathway.
Amino acid metabolism-related genes as potential biomarkers and the role of MATN3 in stomach adenocarcinoma: A bioinformatics, mendelian randomization and experimental validation study.
Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis.
Intersectin1 promotes clathrin-mediated endocytosis by organizing and stabilizing endocytic protein interaction networks.
Tak1 licenses mitochondrial transfer from astrocytes to POMC neurons to maintain glucose and cholesterol homeostasis.
Doublecortin regulates the mitochondrial-dependent apoptosis in glioma via Rho-A/Net-1/p38-MAPK signaling.
Rapamycin and Niacin combination induces apoptosis and cell cycle arrest through autophagy activation on acute myeloid leukemia cells.
A mucus layer derived from porcine intestinal organoid air-liquid interface monolayer attenuates swine enteric coronavirus infection by antiviral activity of Muc2.
Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction.
ANXA1-FPR2 axis mitigates the susceptibility to atrial fibrillation in obesity via rescuing AMPK activity in response to lipid overload.
Exosomes derived from hypoxic mesenchymal stem cells restore ovarian function by enhancing angiogenesis.
Salivary adenoid cystic carcinoma-derived α2,6-sialylated extracellular vesicles increase vascular permeability by triggering ER-stress in endothelial cells and promote lung metastasis.
JAG1 mediates apoptosis in herpes simplex keratitis by suppressing autophagy via ROS/JAG1/NOTCH1/pULK1 signaling pathway.
Zinc finger protein 593 promotes breast cancer development by ensuring DNA damage repair and cell-cycle progression.
lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing.
KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus.
NCAM1 modulates the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary hypertension.
17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson's disease.
Apigenin Reduces Lipid Droplet Accumulation in Hepatocytes by Enhancing Chaperone-Mediated Autophagy via AMPK.
Bexarotene ameliorated the pulmonary inflammation and M1 polarization of alveolar macrophages induced by cigarette smoke via PPARγ/HO-1.
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
miR-184, a downregulated ovary-elevated miRNA transcriptionally activated by SREBF2, exerts anti-apoptotic properties in ovarian granulosa cells through inducing SMAD3 expression.
Network pharmacology and anticancer mechanism study of Dendrobium nobile dendrobine in the treatment of colorectal cancer.
Exploring PDE5A upregulation in bipolar disorder: insights from single-nucleus RNA sequencing of human basal ganglia.
Dynamic Detection of the E3-PROTAC-Target Protein Ternary Complex In Vitro and In Vivo via Bimolecular Fluorescence Complementation.
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism.
LncRNA Expression Profiles in C6 Ceramide Treatment Reveal lnc_025370 as a Promoter in Canine Mammary Carcinoma CHMp Cells Progression.
Mechano-induced arachidonic acid metabolism promotes keratinocyte proliferation through cPLA2 activity regulation.
Design, synthesis and biological evaluation of novel benzimidazole-derived p21-activited kinase 4 (PAK4) inhibitors bearing a 4-(4-methylpiperazin-1-yl)phenyl scaffold as potential antitumor agents.
Methyltransferase METTL3 regulates neuropathic pain through m6A methylation modification of SOCS1.
The molecular mechanisms by which the NLRP3 inflammasome regulates blood-brain barrier permeability following cryptococcal meningitis.
Systematic exploration of the molecular characteristics of CD8(+) T cells to predict the response to immunotherapy and the prognosis of patients with colon adenocarcinoma.
Inhibition of AhR disrupts intestinal epithelial barrier and induces intestinal injury by activating NF-κB in COPD.
Molecular Analysis of the Differential Activity of Sox8 and Sox10 in Oligodendroglial Cells.
OGT promotes the ferroptosis of chondrocytes in osteoarthritis development via O-GlcNAcylation modification of ACSF2.
GsMTx4 Combined with Exercise Exerts Neuroprotective Effects by Regulating Neuronal Autophagy in Rats with Spinal Cord Injury.
Accumulation of Advanced Oxidation Protein Products Promotes Age-Related Decline of Type H Vessels in Bone.
Therapeutic potential of farnesoid X receptor agonists for modulating inflammation and periodontal regeneration.
Spike-In Proteome Enhances Data-Independent Acquisition for Thermal Proteome Profiling.
TRIM24-DTNBP1-ATP7A mediated astrocyte cuproptosis in cognition and memory dysfunction caused by Y(2)O(3) NPs.
TIGAR relieves PCOS by inhibiting granulosa cell apoptosis and oxidative stress through activating Nrf2.
CLEC14A facilitates angiogenesis and alleviates inflammation in diabetic wound healing.
17β-Estradiol Ameliorates Postoperative Cognitive Dysfunction in Aged Mice via miR-138-5p/SIRT1/HMGB1 Pathway.
TRPM7 contributes to pyroptosis and its involvement in status epilepticus.
O-GlcNAc participates in the meiosis of aging oocytes by mediating mitochondrial function.
Hydrogen sulfide ameliorated endothelial dysfunction in hyperhomocysteinemia rats: Mechanism of IRE1α/JNK pathway-mediated autophagy.
The USP11/Nrf2 positive feedback loop promotes colorectal cancer progression by inhibiting mitochondrial apoptosis.
Discovery and optimization of anthraquinone derivatives containing substituted bisbenzyloxy groups as a novel scaffold damaged endoplasmic reticulum and against hepatocellular carcinoma cells.
Sleep deprivation induced fat accumulation in the visceral white adipose tissue by suppressing SIRT1/FOXO1/ATGL pathway activation.
Sulforaphane impaired immune checkpoint blockade therapy through activating ΔNP63α/PD-L1 axis in gastric cancer.
Improvement of functional dyspepsia with Suaeda salsa (L.) Pall via regulating brain-gut peptide and gut microbiota structure.
MicroRNA miR-145-5p Inhibits Cutaneous Wound Healing by Targeting PDGFD in Diabetic Foot Ulcer.
CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex.
HO-1-induced autophagy establishes a HO-1-p62-Nrf2 positive feedback loop to reduce gut permeability in cholestatic liver disease.
Capsaicin attenuates Porphyromonas gingivalis-suppressed osteogenesis of periodontal ligament stem cells via regulating mitochondrial function and activating PI3K/AKT/mTOR pathway.
Matrix stiffness regulates macrophage polarisation via the Piezo1-YAP signalling axis.
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Digitoxin inhibits ICC cell properties via the NF‑κB/ST6GAL1 signaling pathway.
DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis.
Lycorine relieves the CCl(4)-induced liver fibrosis mainly via the JAK2/STAT3 and PI3K/AKT signaling pathways.
Zinc finger protein 367 exerts a cancer-promoting role in small cell lung cancer by influencing the CIT/LATS2/YAP signaling cascade.
Decreasing of serine/threonine kinase 39 has tumour inhibiting effects on acute myeloid leukaemia by impacting the PI3K/AKT and Wnt/β-catenin signalling cascades.
Osthole exhibits the remedial potential for polycystic ovary syndrome mice through Nrf2-Foxo1-GSH-NF-κB pathway.
Hematoporphyrin derivative-mediated photodynamic techniques for the diagnosis and treatment of chordoma.
Adrenomedullin improved endothelial dysfunction via receptor-Akt pathway in rats with obesity-related hypertension.
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Integration of serum pharmacochemistry with network pharmacology to reveal the potential mechanism of Yangqing Chenfei formula for the treatment of silicosis.
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Autocatalytic, Brain Tumor-Targeting Delivery of Bardoxolone Methyl Self-Assembled Nanoparticles for Glioblastoma Treatment.
Identification of residues in Lassa virus glycoprotein 1 involved in receptor switch.
miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway.
Clonorchis sinensis aggravated liver fibrosis by activating PARP-1 signaling to induce parthanatos via DNA damage.
Circ_0000595 knockdown alleviates CoCl2-mediated effects in VSMCs by regulating the miR-582-3p/ADAM10 axis.
Silicone dressing combined with topical oxygen therapy alleviates incontinence-associated dermatitis via NF-κB p65/STAT1 signaling pathway.
Computational biology-based study of the molecular mechanism of spermidine amelioration of acute pancreatitis.
SENP1 reduces oxidative stress and apoptosis in renal ischaemia-reperfusion injury by deSUMOylation of HIF-1α.
PLCγ1 deficiency in chondrocytes accelerates the age-related changes in articular cartilage and subchondral bone.
Ophiopogonin D' inhibited tumour growth and metastasis of anaplastic thyroid cancer by modulating JUN/RGS4 signalling.
The long noncoding RNA lncMPD2 inhibits myogenesis by targeting the miR-34a-5p/THBS1 axis.
Tetrastigma hemsleyanum polysaccharide combined with doxorubicin promote ferroptosis and immune function in triple-negative breast cancer.
Genome-wide epigenetic signatures facilitated the variant classification of the PURA gene and uncovered the pathomechanism of PURA-related neurodevelopmental disorders.
miR-218-5p promotes hepatic lipogenesis through targeting Elovl5 in non-alcoholic fatty liver disease.
Increased PHLPP1 expression through ERK-4E-BP1 signaling axis drives nicotine induced oxidative stress related damage of cardiomyocytes.
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Bongkrekic acid alleviates airway inflammation via breaking the mPTP/mtDAMPs/RAGE feedback loop in a steroid-insensitive asthma model.
The secoiridoid glycoside Gentiopicroside is a USP22 inhibitor with potent antitumor immunotherapeutic activity.
The PD-1 /PD-L1 signaling pathway regulates decidual macrophage polarization and may participate in preeclampsia.
Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway.
Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement.
Apolipoprotein A-IV restrains fat accumulation in skeletal and myocardial muscles by inhibiting lipogenesis and activating PI3K-AKT signalling.
Expression profiles of miRNAs in the lung tissue of piglets infected with Glaesserella parasuis and the roles of ssc-miR-135 and ssc-miR-155-3p in the regulation of inflammation.
Ultrasonic-assisted extraction of a low molecular weight polysaccharide from Nostoc commune Vaucher and its structural characterization and immunomodulatory activity.
Berberine alleviates high-energy and low-protein diet-induced fatty liver hemorrhagic syndrome in laying hens: insights from microbiome and metabolomics.
Effects of Smilax China L. extracts on Hyperuricemia chicken model via inhibiting xanthine oxidase activity.
Inhibitory effects of Belamcanda extract on inflammatory response and antiviral mechanism in H9N2 Avian influenza virus: insights from in vitro and in vivo studies.
Isoliquiritigenin attenuates myocardial ischemia reperfusion through autophagy activation mediated by AMPK/mTOR/ULK1 signaling.
CYLD/HDAC6 signaling regulates the interplay between epithelial-mesenchymal transition and ciliary homeostasis during pulmonary fibrosis.
The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.
Antidepressant Sertraline Synergistically Enhances Paclitaxel Efficacy by Inducing Autophagy in Colorectal Cancer Cells.
SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis.
NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling.
Adhesion of pancreatic tumor cell clusters by desmosomal molecules enhances early liver metastases formation.
miR-143-3p modulates depressive-like behaviors via Lasp1 in the mouse ventral hippocampus.
DAPK1 mediates cognitive dysfunction and neuronal apoptosis in PSD rats through the ERK/CREB/BDNF signaling pathway.
Anticancer effects of Erzhimaoling decoction in high-grade serous ovarian cancer in vitro and in vivo.
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Actomyosin-II protects axons from degeneration induced by mild mechanical stress.
Metformin enhances endogenous neural stem cells proliferation, neuronal differentiation, and inhibits ferroptosis through activating AMPK pathway after spinal cord injury.
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
LINC01605 promotes malignant phenotypes of cervical cancer via miR-149-3p/WNT7B axis.
KAT7 serves as an oncogenic gene and regulates CCL3 expression via STAT1 signaling in osteosarcoma.
Targeting m7G-enriched circKDM1A prevents colorectal cancer progression.
MicroRNA-650 promotes melanoma metastasis via targeting inhibitor of growth family member 4.
Synergistic effects of plasma-activated medium in combination with Baicalin against neuronal damage.
GFPT1 accelerates immune escape in breast cancer by modifying PD-L1 via O-glycosylation.
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Extracellular Vesicle Inhibitors Enhance Cholix-Induced Cell Death via Regulation of the JNK-Dependent Pathway.
CTDSPL2 promotes the progression of non-small lung cancer through PI3K/AKT signaling via JAK1.
Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation.
Homologous Tumor Cell-Derived Biomimetic Nano-Trojan Horse Integrating Chemotherapy with Genetherapy for Boosting Triple-Negative Breast Cancer Therapy.
Potential mechanism prediction of indole-3-propionic acid against diminished ovarian reserve via network pharmacology, molecular docking and experimental verification.
Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs-GPR-GLP1 signal axis.
The Kv4 potassium channel modulator NS5806 attenuates cardiac hypertrophy in vivo and in vitro.
Proteolysis targeting chimera extracellular vesicles for therapeutic development treating triple negative breast cancer.
Youthful small extracellular vesicles restore the function and reparative capacity of inflammatory-impaired periodontal ligament stem cells via delivering protein biglycan for bone regeneration.
Extracellular vesicle-bound VEGF in oral squamous cell carcinoma and its role in resistance to Bevacizumab Therapy.
PINX1 loss confers susceptibility to PARP inhibition in pan-cancer cells.
Ribonuclease Inhibitor 1 (RNH1) Regulates Sperm tsRNA Generation for Paternal Inheritance through Interacting with Angiogenin in the Caput Epididymis.
Two-polarized roles of transcription factor FOSB in lung cancer progression and prognosis: dependent on p53 status.
Extracellular Vesicle-Associated Neutrophil Elastase Activates Hepatic Stellate Cells and Promotes Liver Fibrogenesis via ERK1/2 Pathway.
ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency.
Interleukin-33 promotes intrauterine adhesion formation in mice through the mitogen-activated protein kinase signaling pathway.
Quantitative Proteomics Reveal the Mechanism of MiR-138-5p Suppressing Cervical Cancer via Targeting ZNF385A.
Integrative Analysis of Lactylome and Proteome of Hypertrophic Scar To Identify Pathways or Proteins Associated with Disease Development.
Sestrin2 knockout exacerbates high-fat diet induced metabolic disorders and complications in female mice.
Immediate myeloid depot for SARS-CoV-2 in the human lung.
SelK promotes glioblastoma cell proliferation by inhibiting β-TrCP1 mediated ubiquitin-dependent degradation of CDK4.
Splicing Factor PTBP1 Silencing Induces Apoptosis of Human Cervical Cancer Cells via PI3K/AKT Pathway and Autophagy.
The role and mechanism of thrombospondin-4 in pulmonary arterial hypertension associated with congenital heart disease.
Telomerase related molecular subtype and risk model reveal immune activity and evaluate prognosis and immunotherapy response in prostate cancer.
SERPINH1 modulates apoptosis by inhibiting P62 ubiquitination degradation to promote bone metastasis of prostate cancer.
Targeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling.
Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis.
Catalpol inhibits HHcy-induced EndMT in endothelial cells by modulating ROS/NF-κB signaling.
The M2 Protein of the Influenza A Virus Interacts with PEX19 to Facilitate Virus Replication by Disrupting the Function of Peroxisome.
Construction of mitochondrial-targeting nano-prodrug for enhanced Rhein delivery and treatment for osteoarthritis in vitro.
Potential mechanisms of aortic medial degeneration promoted by co-exposure to microplastics and lead.
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Integrating bulk and single-cell sequencing reveals metastasis-associated CAFs in head and neck squamous cell carcinoma.
In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP.
Decreased thrombospondin-1 impairs endometrial stromal decidualization in unexplained recurrent spontaneous abortion†.
Exploring the relationship between pyroptosis and inflammatory bone loss: Evidence from a cigarette smoke-induced osteoporosis mouse model.
MicroRNA-2861 regulates the proliferation and apoptosis of human retinal vascular endothelial cells treated with high glucose by targeting NDUFB7.
Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models.
Dextran sulfate inhibits proliferation and metastasis of human gastric cancer cells via miR-34c-5p.
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Nilotinib boosts the efficacy of anti-PDL1 therapy in colorectal cancer by restoring the expression of MHC-I.
Gene therapy in Aβ-induced cell and mouse models of Alzheimer's disease through compensating defective mitochondrial complex I function.
A structured biomimetic nanoparticle as inflammatory factor sponge and autophagy-regulatory agent against intervertebral disc degeneration and discogenic pain.
The histamine receptor H1 acts as an alternative receptor for SARS-CoV-2.
Orai1 and Orai3 act through distinct signalling axes to promote stemness and tumorigenicity of breast cancer stem cells.
Characterization of Novel PHEX Variants in X-linked Hypophosphatemic Rickets and Genotype-PHEX Activity Correlation.
Heavy Metal Exposure-Mediated Dysregulation of Sphingolipid Metabolism.
Activated STING-containing R-EVs from iPSC-derived MSCs promote antitumor immunity.
The deubiquitinase USP2a promotes tumor immunosuppression by stabilizing immune checkpoint B7-H4 in lung adenocarcinoma harboring EGFR-activating mutants.
A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.
Asprosin contributes to vascular remodeling in hypertensive rats via superoxide signaling.
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
The parkin V380L variant is a genetic modifier of Machado-Joseph disease with impact on mitophagy.
Discovery and evaluation of novel spiroheterocyclic protective agents via a SIRT1 upregulation mechanism in cisplatin-induced premature ovarian failure.
CPEB1 induces autophagy and promotes apoptosis in ovarian granulosa cells of polycystic ovary syndrome.
Interleukin-19 enhances eosinophil infiltration through upregulation of epithelium-derived RANTES expression via the ERK/NF-κB signalling pathway in patients with eosinophilic CRSwNP.
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF-β1 /P-smad3 signaling through HIF-1a.
STAT4-Mediated Klotho Up-Regulation Contributes to the Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning via Inhibiting Neuronal Pyroptosis.
PRDX6 alleviated heart failure by inhibiting doxorubicin-induced ferroptosis through the JAK2/STAT1 pathway inactivation.
Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis.
Transcriptomic analysis of rat brain response to alternating current electrical stimulation: unveiling insights via single-nucleus RNA sequencing.
Long Non-Coding RNA ANRIL Regulates Inflammatory Factor Expression in Ulcerative Colitis Via the miR-191-5p/SATB1 Axis.
Bioinformatics analysis and experimental validation reveal that CDC20 overexpression promotes bladder cancer progression and potential underlying mechanisms.
E3 ubiquitin ligase NEDD4L inhibits epithelial-mesenchymal transition by suppressing the β-catenin/HIF-1α positive feedback loop in chronic rhinosinusitis with nasal polyps.
Inflammatory Factor IL1α Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca(2+)/CaMK2b Pathway.
Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis.
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Induction of apoptosis and autophagy by dichloromethane extract from Patrinia scabiosaefolia Fisch on acute myeloid leukemia cells.
Integrated network pharmacology, molecular docking and pharmacodynamic study reveals protective effects and mechanisms of corilagin against cerebral ischemia-induced injury.
Valeric acid reduction by chitosan oligosaccharide induces autophagy in a Parkinson's disease mouse model.
Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-κB signaling pathway through modification of the Src/TRAF6/TAK1 axis.
Pseudolaric acid B exerts an antifungal effect and targets SIRT1 to ameliorate inflammation by regulating Nrf2/NF-κB pathways in fungal keratitis.
Mitochondria-associated endoplasmic reticulum membrane as a mediator of vanadium-induced endoplasmic reticulum quality control in duck brains.
Nicotine suppresses crystalline silica-induced astrocyte activation and neuronal death by inhibiting NF-κB in the mouse hippocampus.
A TGF-β signaling-related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response.
Effect and mechanism of fluctuant glucose on restraining implant osseointegration in diabetes.
SOX18 meditates the resistance of Bmi1-expressing cells to cetuximab in HNSCC.
Ataxin-2 sequesters Raptor into aggregates and impairs cellular mTORC1 signaling.
GHITM regulates malignant phenotype and sensitivity to PD-1 blockade of renal cancer cells via Notch signalling.
CCDC157 is essential for sperm differentiation and shows oligoasthenoteratozoospermia-related mutations in men.
BUB1/KIF14 complex promotes anaplastic thyroid carcinoma progression by inducing chromosome instability.
Integrating Network Pharmacology and Experimental Validation to Reveal the Mechanism of Vine Grape Tea Polyphenols on Hyperuricemia-Induced Renal Injury in Mice.
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Paclitaxel mediates the PI3K/AKT/mTOR pathway to reduce proliferation of FLT3‑ITD(+) AML cells and promote apoptosis.
Programmed cell death 4 blocks autophagy and promotes dopaminergic neuronal injury in Parkinson's disease.
Porcine deltacoronavirus NS7a antagonizes JAK/STAT pathway by inhibiting the interferon-stimulated gene factor 3 (ISGF3) formation.
Tumor cell-derived LC3B(+)extracellular vesicles mediate the crosstalk between tumor microenvironment and immunotherapy efficacy in hepatocellular carcinoma via the HSP90α-IL-6/IL-8 signaling axis.
Longitudinal skeletal growth and growth plate morphological characteristics of chondro-tissue specific CUL7 knockout mice.
Effects of Halloysite Nanotubes and Multi-walled Carbon Nanotubes on Kruppel-like Factor 15-Mediated Downstream Events in Mouse Hearts After Intravenous Injection.
PGC-1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons.
Icariin attenuates vascular endothelial dysfunction by inhibiting inflammation through GPER/Sirt1/HMGB1 signaling pathway in type 1 diabetic rats.
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Resveratrol Inhibits Zinc Deficiency-Induced Mitophagy and Exerts Cardiac Cytoprotective Effects.
Exosome-based WTAP siRNA delivery ameliorates myocardial ischemia-reperfusion injury.
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
Arsenic disturbs neural tube closure involving AMPK/PKB-mTORC1-mediated autophagy in mice.
3-Monochloropropane-1,2-diol esters induce HepG2 cells necroptosis via CTSB/TFAM/ROS pathway.
Decreased FGF23 inhibits placental angiogenesis via the ERK1/2-EGR-1 signaling pathway in preeclampsia.
Oseltamivir enhances 5-FU sensitivity in esophageal squamous carcinoma with high SPNS1.
Icariin alleviates diabetic renal interstitial fibrosis aggravation by inhibiting miR-320a-3p targeting BMP6.
N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.
N6-methyladenosine-modified circTEAD1 stabilizes Yap1 mRNA to promote chordoma tumorigenesis.
Oleanolic acid alleviates obesity-induced skeletal muscle atrophy via the PI3K/Akt signaling pathway.
Knocking down GRAMD1C expression reduces 6-OHDA-induced apoptosis in PC12 cells.
Rosmarinic acid mitigates acrylamide induced neurotoxicity via suppressing endoplasmic reticulum stress and inflammation in mouse hippocampus.
Baohuoside I suppresses the NLRP3 inflammasome activation via targeting GPER to fight against Parkinson's disease.
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
H(2)S-Releasing Versatile Montmorillonite Nanoformulation Trilogically Renovates the Gut Microenvironment for Inflammatory Bowel Disease Modulation.
Effects of 1,4-dihydropyridine derivatives on cell injury and mTOR of HepG2 and 3D-QSAR study.
Impact of endocrine-active compounds on adrenal androgen production in pigs during neonatal period.
Targeting Mitochondrial Complex I Deficiency in MPP(+)/MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene.
HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer.
ATP Citrate Lyase is a General Tumour Biomarker and Contributes to the Development of Cutaneous Squamous Cell Carcinoma.
Enhancing Skin Injury Repair: Combined Application of PF-127 Hydrogel and hADSC-Exos Containing miR-148a-3p.
NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16.
Uncovering the key pharmacodynamic material basis and possible molecular mechanism of Xiaoke formulation improve insulin resistant through a comprehensive investigation.
Guben Qingfei decoction attenuates LPS-induced acute lung injury by modulating the TLR4/NF-κB and Keap1/Nrf2 signaling pathways.
Protective effects of Huang-Qi-Ge-Gen decoction against diabetic liver injury through regulating PI3K/AKT/Nrf2 pathway and metabolic profiling.
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence.
Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer.
Transcranial direct current stimulation promotes angiogenesis and improves neurological function via the OXA-TF-AKT/ERK signaling pathway in traumatic brain injury.
Proteomic analysis of DEN and CCl(4)-induced hepatocellular carcinoma mouse model.
Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans.
Pyrotinib is effective in both trastuzumab-sensitive and primary resistant HER2-positive breast tumors.
Nitro-oleic acid (NO(2)-OA) ameliorates erectile dysfunction in a rat model of diabetes mellitus via modulation of fibrosis, inflammation and autophagy.
DNMT3A promotes glioma growth and malignancy via TNF-α/NF-κB signaling pathway.
RBM39 is a potential prognostic biomarker with functional significance in hepatocellular carcinoma.
Mesothelin promotes brain metastasis of non-small cell lung cancer by activating MET.
Electroacupuncture promotes macrophage/microglial M2 polarization and suppresses inflammatory pain through AMPK.
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
Comparative Analysis of Site-Specific N-glycosylation of LAMP1 from Breast Cancer Tissues.
Cetuximab-Toxin Conjugate and NPe6 with Light Enhanced Cytotoxic Effects in Head and Neck Squamous Cell Carcinoma In Vitro.
Induction of IFIT1/IFIT3 and inhibition of Bcl-2 orchestrate the treatment of myeloma and leukemia via pyroptosis.
SYVN1 modulates papillary thyroid carcinoma progression by destabilizing HMGB1.
Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats.
CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway.
Mechanism of ameliorating cerebral ischemia/reperfusion injury by antioxidant inhibition of autophagy based on network pharmacology and experimental verification.
Network pharmacology and experimental validation of effects of total saponins extracted from Abrus cantoniensis Hance on acetaminophen-induced liver injury.
Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation.
GFRA4 improves the neurogenic potential of enteric neural crest stem cells via hedgehog pathway.
hnRNPU is required for spermatogonial stem cell pool establishment in mice.
25-hydroxycholesterol promotes proliferation and metastasis of lung adenocarcinoma cells by regulating ERβ/TNFRSF17 axis.
Intersectin1 promotes clathrin-mediated endocytosis by organizing and stabilizing endocytic protein interaction networks.
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
FTO promotes gastric cancer progression by modulating MAP4K4 expression via demethylation in an m6A-dependent manner.
Unraveling the interplay of ferroptosis and immune dysregulation in diabetic kidney disease: a comprehensive molecular analysis.
Esculin targets TLR4 to protect against LPS-induced septic cardiomyopathy.
MGP(+) and IDO1(+) tumor-associated macrophages facilitate immunoresistance in breast cancer revealed by single-cell RNA sequencing.
The coumarin component isofraxidin targets the G-protein-coupled receptor S1PR1 to modulate IL-17 signaling and alleviate ulcerative colitis.
Physalin H ameliorates LPS-induced acute lung injury via KEAP1/NRF2 axis.
Ketogenic diet ameliorates high-fat diet-induced insulin resistance in mouse skeletal muscle by alleviating endoplasmic reticulum stress.
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5.
CCNA2 and KIF23 are molecular targets for the prognosis of adenoid cystic carcinoma.
Urolithin B reduces cartilage degeneration and alleviates osteoarthritis by inhibiting inflammation.
Islet-resident macrophage-derived miR-155 promotes β cell decompensation via targeting PDX1.
A prognostic and immune related risk model based on zinc homeostasis in hepatocellular carcinoma.
A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice.
Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling.
Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice.
Biochemical analysis of the host factor activity of ZCCHC14 in hepatitis A virus replication.
PEI, a new transfection method, augments the inhibitory effect of RBM5 on prostate cancer.
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake.
Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice.
JMJD3 activation contributes to renal protection and regeneration following acute kidney injury in mice.
Preliminary investigation into the impact of BPA on osteoblast activity and bone development: In vitro and in vivo models.
Phthalate exposure aggravates periodontitis by activating NFκB pathway.
Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction.
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
A mutation in LPAR2 activates the miR-939-5p-LPAR2-PI3K/AKT axis to regulate the proliferation and apoptosis of granulosa cells in sheep.
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Live Cell Monitoring of Separase Activity, a Key Enzymatic Reaction for Chromosome Segregation, with Chimeric FRET-Based Molecular Sensor upon Cell Cycle Progression.
Artesunate induces ferroptosis by regulating MT1G and has an additive effect with doxorubicin in diffuse large B-cell lymphoma cells.
Endothelin-1-mediated Brainstem Glial Activation Produces Asthmatic Airway Vagal Hypertonia Via Enhanced ATP-P2X4 Receptor Signaling in Sprague-Dawley Rats.
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase.
Tyrosine hydroxylase inhibits HCC progression by downregulating TGFβ/Smad signaling.
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology.
Zyxin is important for the stability and function of podocytes, especially during mechanical stretch.
Design, Synthesis, and Activity Evaluation of Fluorine-Containing Scopolamine Analogues as Potential Antidepressants.
METTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis.
Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression.
Galangin Prevents Against Ethanol-Induced Intestinal Barrier Dysfunction and NLRP3 Inflammasome Activation via NF-κB/MAPK Signaling Pathways in Mice and Caco-2 Cells.
In Vitro Comparative Analysis of the Effect and Structure-Based Influencing Factors of Flavonols on Lipid Accumulation.
DHCR24 Insufficiency Promotes Vascular Endothelial Cell Senescence and Endothelial Dysfunction via Inhibition of Caveolin-1/ERK Signaling.
Identification of Novel FZD4 Mutations in Familial Exudative Vitreoretinopathy and Investigating the Pathogenic Mechanisms of FZD4 Mutations.
Up-regulation of RAN by MYBL2 maintains osteosarcoma cancer stem-like cells population during heterogeneous tumor generation.
Renalase mediates macrophage-to-fibroblast crosstalk to attenuate pressure overload-induced pathological myocardial fibrosis.
Protective role of forsythoside B in Kawasaki disease-induced cardiac injury: Inhibition of pyroptosis via the SIRT1-NF-κB-p65 signaling pathway.
KRAS Mutation Detection with (2S,4R)-4-[(18)F]FGln for Noninvasive PDAC Diagnosis.
Bone marrow-derived mesenchymal stem cell-conditioned medium ameliorates diabetic foot ulcers in rats.
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Ellagic acid alleviates TNBS-induced intestinal barrier dysfunction by regulating mucin secretion and maintaining tight junction integrity in rats.
Harnessing nanobodies for target protein degradation through the Affinity-directed PROtein Missile (AdPROM) system.
The PPARα/CYP4A14 bile acid pathway is associated with lipid metabolism disorders caused by low birth weight with high-fat diet.
The role of miR-369-3p in proliferation and differentiation of preadipocytes in Aohan fine-wool sheep.
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Hepatocellular SETDB1 Regulates Hepatic Ischemia-Reperfusion Injury through Targeting Lysine Methylation of ASK1 Signal.
Preclinical study of LMP1-RNAi-based anti-tumor therapy in EBV-positive nasopharyngeal carcinoma.
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
Tetrandrine Inhibits Cancer Stem Cell Characteristics and Epithelial to Mesenchymal Transition in Triple-Negative Breast Cancer via SOD1/ROS Signaling Pathway.
Oxidative stress and cellular toxicity induced by dihydropyrazine: a comparative study with other Maillard reaction products.
A Complex of Type I Platelet-Activating Factor Acetylhydrolase (PAF-AH) Catalytic Subunits Switches from α1/α2 Heterodimer to α2/α2 Homodimer during Adipocyte Differentiation of 3T3-L1 Cells.
Exosomal miR-133a-3p promotes the growth and metastasis of lung cancer cells following incomplete microwave ablation.
HMGB1 released from dead tumor cells after insufficient radiofrequency ablation promotes progression of HCC residual tumor via ERK1/2 pathway.
Immunological function and prognostic value of lymphoid-specific helicase in liver hepatocellular carcinoma.
FKBP11 upregulation promotes proliferation and migration in hepatocellular carcinoma.
Apolipoprotein C1 promotes tumor progression in gastric cancer.
Sulforaphane inhibits TGF-β-induced fibrogenesis and inflammation in human Tenon's fibroblasts.
The impacts of resveratrol on the retinal degeneration in a rat model of retinitis pigmentosa induced by alkylation: an in-vivo study.
Indirubin alleviates CCl(4)-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways.
Static Magnetic Field Promotes Proliferation, Migration, Differentiation, and AKT Activation of Periodontal Ligament Stem Cells.
MiR-216a reduces apoptosis of pulmonary microvascular endothelial cells in COPD by targeting DNMT1.
TRIM6 Reduces Ferroptosis and Chemosensitivity by Targeting SLC1A5 in Lung Cancer.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Identification of a Five Immune Term Signature for Prognosis and Therapy Options (Immunotherapy versus Targeted Therapy) for Patients with Hepatocellular Carcinoma.
Long Noncoding RNA SAMMSON Promotes Melanoma Progression by Inhibiting FOXA2 Expression.
miR-135a Regulates Atrial Fibrillation by Targeting Smad3.
hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells.
Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction.
Huoxiang Zhengqi Oral Liquid Attenuates LPS-Induced Acute Lung Injury by Modulating Short-Chain Fatty Acid Levels and TLR4/NF-κB p65 Pathway.
GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells.
Enriched Environment Attenuates Ferroptosis after Cerebral Ischemia/Reperfusion Injury via the HIF-1α-ACSL4 Pathway.
lncRNA MEG3 Promotes PDK4/GSK-3β/β-Catenin Axis in MEFs by Targeting miR-532-5p.
Effects of Fibulin-5 Gene Silencing on Proliferation and Apoptosis of IgG4-ROD Lacrimal Gland Fibroblasts.
Study on the Mechanism of Jiaotai Pill Intervention on Insomnia Animal Model Based on Gut Microbiome and Metabolomics.
HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model.
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Circular RNA_HIPK3-Targeting miR-93-5p Regulates KLF9 Expression Level to Control Acute Kidney Injury.
STARD12/14 are diagnostic and prognostic biomarkers of lung adenocarcinoma associated with epigenetic regulation, immune infiltration and ferroptosis.
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.
LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2.
Tectorigenin targets PKACα to promote GLUT4 expression in skeletal muscle and improve insulin resistance in vitro and in vivo.
TNFR2 deficiency impairs the growth of mouse colon cancer.
Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation.
BGN/FAP/STAT3 positive feedback loop mediated mutual interaction between tumor cells and mesothelial cells contributes to peritoneal metastasis of gastric cancer.
XPOT Disruption Suppresses TNBC Growth through Inhibition of Specific tRNA Nuclear Exportation and TTC19 Expression to Induce Cytokinesis Failure.
Polyphyllin VII induces CTC anoikis to inhibit lung cancer metastasis through EGFR pathway regulation.
Intergenic CircRNA Circ_0007379 Inhibits Colorectal Cancer Progression by Modulating miR-320a Biogenesis in a KSRP-Dependent Manner.
11β-Hydroxysteroid Dehydrogenase Type 1 Facilitates Osteoporosis by Turning on Osteoclastogenesis through Hippo Signaling.
Nicotinamide adenine dinucleotide kinase promotes lymph node metastasis of NSCLC via activating ID1 expression through BMP pathway.
Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function.
M2b macrophages protect against doxorubicin induced cardiotoxicity via alternating autophagy in cardiomyocytes.
Chaperone-mediated autophagy promotes breast cancer angiogenesis via regulation of aerobic glycolysis.
Identification of circRNA-miRNA-mRNA regulatory network and its role in cardiac hypertrophy.
Electrophysiological evaluation of an anticancer drug gemcitabine on cardiotoxicity revealing down-regulation and modification of the activation gating properties in the human rapid delayed rectifier potassium channel.
Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Downregulation of RBM17 enhances cisplatin sensitivity and inhibits cell invasion in human hypopharyngeal cancer cells.
Combining Porous Se@SiO(2) Nanocomposites and dECM Enhances the Myogenic Differentiation of Adipose-Derived Stem Cells.
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Pluronic F-127 Hydrogel Loaded with Human Adipose-Derived Stem Cell-Derived Exosomes Improve Fat Graft Survival via HIF-1α-Mediated Enhancement of Angiogenesis.
MicroRNA Let-7 Induces M2 Macrophage Polarization in COPD Emphysema Through the IL-6/STAT3 Pathway.
A Pegylated Liposome Loaded with Raddeanin A for Prostate Cancer Therapy.
Promoted Abutment-Soft Tissue Integration Around Self-Glazed Zirconia Surfaces with Nanotopography Fabricated by Additive 3D Gel Deposition.
Polydopamine Nanoparticles-Based Photothermal Effect Against Adhesion Formation in a Rat Model of Achilles Tendon Laceration Repair.
Combined Verapamil-Polydopamine Nanoformulation Inhibits Adhesion Formation in Achilles Tendon Injury Using Rat Model.
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Icariin reduces cognitive dysfunction induced by surgical trauma in aged rats by inhibiting hippocampal neuroinflammation.
17β-estradiol inhibits TGF-β-induced collagen gel contraction mediated by human Tenon fibroblasts via Smads and MAPK signaling pathways.
Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans.
Neutrophil Extracellular Traps Induce Alveolar Macrophage Pyroptosis by Regulating NLRP3 Deubiquitination, Aggravating the Development of Septic Lung Injury.
Noncoding RNA-Mediated High Expression of PFKFB3 Correlates with Poor Prognosis and Tumor Immune Infiltration of Lung Adenocarcinoma.
Mastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis.
Unveiling FOS as a Potential Diagnostic Biomarker and Emetine as a Prospective Therapeutic Agent for Diabetic Nephropathy.
Electroacupuncture Alleviates Dry Eye Ocular Pain Through TNF-ɑ Mediated ERK1/2/P2X(3)R Signaling Pathway in SD Rats.
PUS1 May Be a Potential Prognostic Biomarker and Therapeutic Target for Hepatocellular Carcinoma.
High-Dose Vitamin C Alleviates Pancreatic Necrosis by Inhibiting Platelet Activation Through the CXCL12/CXCR4 Pathway in Severe Acute Pancreatitis.
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
Construction and validation of a risk model based on the key SNARE proteins to predict the prognosis and immune microenvironment of gliomas.
Involvement of endoplasmic reticulum stress in trigeminal ganglion corneal neuron injury in dry eye disease.
Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis.
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Hsa_circ_0007823 Overexpression Suppresses the Progression of Triple-Negative Breast Cancer via Regulating miR-182-5p-FOXO1 Axis.
Beneficiary Effects of Colchicine on Inflammation and Fibrosis in a Mouse Model of Kidney Injury.
Orlistat Induces Ferroptosis in Pancreatic Neuroendocrine Tumors by Inactivating the MAPK Pathway.
CHAC2 promotes lung adenocarcinoma by regulating ROS-mediated MAPK pathway activation.
Endoplasmic Reticulum Stress Promotes Prostate Cancer Cells to Release Exosome and Up-regulate PD-L1 Expression via PI3K/Akt Signaling Pathway in Macrophages.
Dihydroartemisinin Potentiates VEGFR-TKIs Antitumorigenic Effect on Osteosarcoma by Regulating Loxl2/VEGFA Expression and Lipid Metabolism Pathway.
ZFP57 promotes ovarian cancer progression by transcriptionally regulating BRCA1 and managing G1 checkpoint.
An Integrated Analysis Identified TAGLN2 As an Oncogene Indicator Related to Prognosis and Immunity in Pan-Cancer.
miR-21-5p Inhibits the Proliferation, Migration, and Invasion of Glioma by Targeting S100A10.
Anti-PAI-1 Monoclonal Antibody Inhibits the Metastasis and Growth of Esophageal Squamous Cell Carcinoma.
Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2.
Integrative analysis of disulfidptosis and immune microenvironment in hepatocellular carcinoma: a putative model and immunotherapeutic strategies.
Leveraging diverse cell-death related signature predicts the prognosis and immunotherapy response in renal clear cell carcinoma.
Investigating the role of NPR1 in dilated cardiomyopathy and its potential as a therapeutic target for glucocorticoid therapy.
Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer.
High expression of P-selectin induces neutrophil extracellular traps via the PSGL-1/Syk/Ca(2+)/PAD4 pathway to exacerbate acute pancreatitis.
Evaluation and mechanism study of Pien Tze Huang against EV-A71 infection.
Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma.
Histone ubiquitination-related gene CUL4B promotes lung adenocarcinoma progression and cisplatin resistance.
Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma.
Immunological characterization of stroke-heart syndrome and identification of inflammatory therapeutic targets.
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice.
Overexpression of DBT suppresses the aggressiveness of renal clear cell carcinoma and correlates with immune infiltration.
RNA-sequencing approach for exploring the protective mechanisms of dexmedetomidine on pancreatic injury in severe acute pancreatitis.
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
Brown adipose tissue-derived exosomes delay fertility decline in aging mice.
Elevated MPP6 expression correlates with an unfavorable prognosis, angiogenesis and immune evasion in hepatocellular carcinoma.
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
N-linoleyltyrosine resisted the growth of non-small cell lung cancer cells via the regulation of CB(1) and CB(2) involvement of PI3K and ERK pathways.
Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity by targeting mitochondrial ROS-mediated ferroptosis.
Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo.
RNA methylation pattern and immune microenvironment characteristics mediated by m6A regulator in ischemic stroke.
Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice.
HZ-A-018, a novel inhibitor of Bruton tyrosine kinase, exerts anti-cancer activity and sensitizes 5-FU in gastric cancer cells.
Reactivation of mutant p53 in esophageal squamous cell carcinoma by isothiocyanate inhibits tumor growth.
Establishment and application of a high-throughput screening model for cell adhesion inhibitors.
Single-cell transcriptomics reveals immune infiltrate in sepsis.
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy.
GPR35 antagonist CID-2745687 attenuates anchorage-independent cell growth by inhibiting YAP/TAZ activity in colorectal cancer cells.
Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense.
Administration of protopine prevents mitophagy and acute lung injury in sepsis.
APOC1 as a novel diagnostic biomarker for DN based on machine learning algorithms and experiment.
Clinical and functional analyses of the novel STAR c.558C>A in a patient with classic lipoid congenital adrenal hyperplasia.
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway.
Investigating the role of FADS family members in breast cancer based on bioinformatic analysis and experimental validation.
Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels.
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway.
Tachykinin receptor 3 in the lateral habenula alleviates pain and anxiety comorbidity in mice.
Low-temperature plasma-activated medium enhances the chemosensitivity of colorectal cancer cells by improving hypoxia.
High expression of peroxisomal D-bifunctional protein in cytosol regulates apoptosis and energy metabolism of hepatocellular carcinoma cells via PI3K/AKT pathway.
Improving the anti-tumor effect of EGCG in colorectal cancer cells by blocking EGCG-induced YAP activation.
Circ8199 encodes a protein that inhibits the activity of OGT by JAK2-STAT3 pathway in esophageal squamous cell carcinoma.
GAPDH: unveiling its impact as a key hypoxia-related player in head and neck squamous cell carcinoma tumor progression, prognosis, and therapeutic potential.
iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway.
Inhibition of OTUB2 suppresses colorectal cancer cell growth by regulating β-Catenin signaling.
DOT1L promotes cell proliferation and invasion by epigenetically regulating STAT5B in renal cell carcinoma.
Combined inhibition of PARP and ATR synergistically potentiates the antitumor activity of HER2-targeting antibody-drug conjugate in HER2-positive cancers.
LncRNA LBX2-AS1 impacts osteosarcoma sensitivity to JQ-1 by sequestering miR-597-3p away from BRD4.
FGFR inhibitors combined with nab-paclitaxel - A promising strategy to treat non-small cell lung cancer and overcome resistance.
Triptolide inhibits the progression of Glioblastoma U251 cells via targeting PROX1.
A pan-cancer analysis of the role of argininosuccinate synthase 1 in human tumors.
BASP1 is a prognostic biomarker associated with immunotherapeutic response in head and neck squamous cell carcinoma.
S100 calcium-binding protein A9 promotes skin regeneration through toll-like receptor 4 during tissue expansion.
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation.
Fascin actin-bundling protein 1 regulates non-small cell lung cancer progression by influencing the transcription and splicing of tumorigenesis-related genes.
Sirtuin 1 alleviates alcoholic liver disease by inhibiting HMGB1 acetylation and translocation.
Identification and validation of hub genes involved in foam cell formation and atherosclerosis development via bioinformatics.
Daidzein alleviates osteoporosis by promoting osteogenesis and angiogenesis coupling.
TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea.
Identification of iron metabolism-related genes as prognostic indicators for papillary thyroid carcinoma: a retrospective study.
Discovery of grey matter lesion-related immune genes for diagnostic prediction in multiple sclerosis.
Pathological mechanism of heart failure with preserved ejection fraction in rats based on iTRAQ technology.
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
Roles of cuproptosis-related gene DLAT in various cancers: a bioinformatic analysis and preliminary verification on pro-survival autophagy.
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Regulation of cleavage embryo genes upon DRP1 inhibition in mouse embryonic stem cells.
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
An miRNA-mRNA integrative analysis in human placentas and mice: role of the Smad2/miR-155-5p axis in the development of fetal growth restriction.
A construct of adipose-derived mesenchymal stem cells-laden collagen scaffold for fertility restoration by inhibiting fibrosis in a rat model of endometrial injury.
Micropatterned composite membrane guides oriented cell growth and vascularization for accelerating wound healing.
Feline umbilical cord-derived mesenchymal stem cells: isolation, identification, and antioxidative stress role through NF-κB signaling pathway.
Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach.
Ischemia/reperfusion-activated ferroptosis in the early stage triggers excessive inflammation to aggregate lung injury in rats.
Berbamine, a bioactive alkaloid, suppresses equine herpesvirus type 1 in vitro and in vivo.
SADS-CoV nsp1 inhibits the IFN-β production by preventing TBK1 phosphorylation and inducing CBP degradation.
Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study.
Hsa_circRNA_0084043 promoting tumorigenesis in glioma through miR-577 sponging.
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization.
EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2.
Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization.
CKBA suppresses mast cell activation via ERK signaling pathway in murine atopic dermatitis.
Exosomal miR-21-5p derived from multiple myeloma cells promote renal epithelial-mesenchymal transition through targeting TGF-β/SMAD7 signalling pathway.
SPAG5, the upstream protein of Wnt and the target of curcumin, inhibits hepatocellular carcinoma.
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
Effects of photodynamic therapy using Red LED-light combined with hypocrellin B on apoptotic signaling in cutaneous squamous cell carcinoma A431 cells.
Hyperoside prevents doxorubicin-induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway.
Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain.
Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment.
ORFV entry into host cells via clathrin-mediated endocytosis and macropinocytosis.
Resveratrol‑mediated activation of SIRT1 inhibits the PERK‑eIF2α‑ATF4 pathway and mitigates bupivacaine‑induced neurotoxicity in PC12 cells.
SLC17A9 expression levels in a pan‑cancer panel and validation of the role of SLC17A9 as a novel prognostic biomarker for osteosarcoma.
High expression of NF-κB inducing kinase in the bulge region of hair follicle induces tumor.
EIF4A3-regulated hsa_circ_0001445 can inhibit the progression of laryngeal squamous cell carcinoma via hsa-miR-432-5p-dependent up-regulation of RGMA expression.
A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance.
Retinal cell-targeted liposomal ginsenoside Rg3 attenuates retinal ischemia-reperfusion injury via alleviating oxidative stress and promoting microglia/macrophage M2 polarization.
Dexmedetomidine alleviates anxiety-like behaviors in female mice with musculoskeletal pain through SIRT1/p53 axis.
HPV E7-drived ALKBH5 promotes cervical cancer progression by modulating m6A modification of PAK5.
Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing.
Engineered Cytokine-Primed Extracellular Vesicles with High PD-L1 Expression Ameliorate Type 1 Diabetes.
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug.
Fgfr1 deficiency in osteocytes leads to increased bone mass by enhancing Wnt/β-catenin signaling.
BLM promotes malignancy in PCa by inducing KRAS expression and RhoA suppression via its interaction with HDGF and activation of MAPK/ERK pathway.
High glucose-induced IL-7/IL-7R upregulation of dermal fibroblasts inhibits angiogenesis in a paracrine way in delayed diabetic wound healing.
Total sesquiterpenoids from Eupatorium lindleyanum DC. attenuate bleomycin-induced lung fibrosis by suppressing myofibroblast transition.
The Chinese medicine Xin-tong-tai granule protects atherosclerosis by regulating oxidative stress through NOX/ROS/NF-κB signal pathway.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Degradation of histone deacetylase 6 alleviates ROS-mediated apoptosis in renal ischemia-reperfusion injury.
PM(2.5) induces the inflammatory response in rat spleen lymphocytes through autophagy activation of NLRP3 inflammasome.
Restraint stress promotes monobenzone-induced depigmentation in mice via the activation of glucocorticoid receptor/macrophage migration inhibitory factor signaling pathway.
IL-21 induces pyroptosis of Treg cells via Akt-mTOR-NLRP3-caspase 1 axis in eosinophilic chronic rhinosinusitis.
Discovery of potent and effective inhibitors containing sulfoxide structures targeting EML4-ALK rearrangement and EGFR mutant non-small cell lung cancer.
Inhibition of Microglial Activation by Delayed Mild Hypothermia Reduced Preoligodendrocyte Injury in a Neonatal Rat Brain Slice Model.
MiR-222-3p suppresses C2C12 myoblast proliferation and differentiation via the inhibition of IRS-1/PI3K/Akt pathway.
GPER governs the immune infiltration of gastric cancer and activates the NF-κB/ROS/Apoptosis pathway in gastric mucosal epithelium.
Artesunate alleviates intestinal ischemia/reperfusion induced acute lung injury via up-regulating AKT and HO-1 signal pathway in mice.
3,4-benzo[a]pyrene aggravates myocardial infarction injury by activating NLRP3-related pyroptosis through PINK1/Parkin-mitophagy-mPTP opening axis.
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis.
Pure total flavonoids from citrus alleviate oxidative stress and inflammation in nonalcoholic fatty liver disease by regulating the miR-137-3p/NOXA2/NOX2 pathway.
FTZ polysaccharides ameliorate kidney injury in diabetic mice by regulating gut-kidney axis.
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor.
Oncogenic Role of the NFATC2/NEDD4/FBP1 Axis in Cholangiocarcinoma.
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
The NLRP11 Protein Bridges the Histone Lysine Acetyltransferase KAT7 to Acetylate Vimentin in the Early Stage of Lung Adenocarcinoma.
A strategy for Cas13 miniaturization based on the structure and AlphaFold.
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.
RGS5 augments astrocyte activation and facilitates neuroinflammation via TNF signaling.
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171.
Vascular wall microenvironment: exosomes secreted by adventitial fibroblasts induced vascular calcification.
HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunction.
Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2.
Activation of AMPK ameliorates acute severe pancreatitis by suppressing pancreatic acinar cell necroptosis in obese mice models.
Effects of infliximab on oxidative stress and inflammation of H9c2 cells induced by H2O2.
LINC00460 promotes angiogenesis by enhancing NF-κB-mediated VEGFA expression in cervical cancer cells.
Cla4 phosphorylates histone methyltransferase Set1 to prevent its degradation by the APC/C(Cdh1) complex.
Derivation of Arbas Cashmere Goat Induced Pluripotent Stem Cells in LCDM with Trophectoderm Lineage Differentiation and Interspecies Chimeric Abilities.
PLCD3 promotes malignant cell behaviors in esophageal squamous cell carcinoma via the PI3K/AKT/P21 signaling.
Identification of common genetic features and pathways involved in pulmonary lymphangioleiomyomatosis and ER-positive breast cancer.
The Effects of Chronic Unpredictable Mild Stress and Semi-Pure Diets on the Brain, Gut and Adrenal Medulla in C57BL6 Mice.
Human osteoarthritic articular cartilage stem cells suppress osteoclasts and improve subchondral bone remodeling in experimental knee osteoarthritis partially by releasing TNFAIP3.
PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C.
Krüppel-like Factor 15 Suppresses Ferroptosis by Activating an NRF2/GPX4 Signal to Protect against Folic Acid-Induced Acute Kidney Injury.
Long intergenic non-coding RNA DIO3OS promotes osteosarcoma metastasis via activation of the TGF-β signaling pathway: a potential diagnostic and immunotherapeutic target for osteosarcoma.
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement.
Synovium is a sensitive tissue for mapping the negative effects of systemic iron overload in osteoarthritis: identification and validation of two potential targets.
METTL3 exerts synergistic effects on m6A methylation and histone modification to regulate the function of VGF in lung adenocarcinoma.
δ-Tocotrienol preconditioning improves the capability of bone marrow-derived mesenchymal stem cells in promoting wound healing by inhibiting BACH1-related ferroptosis.
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
The oncogenic miR-429 promotes triple-negative breast cancer progression by degrading DLC1.
A novel risk model of three gefitinib-related genes FBP1, SBK1 and AURKA is related to the immune microenvironment and is predicting prognosis of lung adenocarcinoma patients.
M(6)A-mediated upregulation of HOXC10 promotes human hepatocellular carcinoma development through PTEN/AKT/mTOR signaling pathway.
Near-Infrared Light-Controlled MicroRNA-21-Loaded Upconversion Nanoparticles to Promote Bone Formation in the Midpalatal Suture.
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Hypoxia-inducible factor upregulation by roxadustat attenuates drug reward by altering brain iron homoeostasis.
Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression.
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.
Kinetin inhibits hepatic stellate cell activation and induces apoptosis via interactions with the TGF-β1/Smad signaling pathway.
FDX1 regulates leydig cell ferroptosis mediates PM(2.5)-induced testicular dysfunction of mice.
Activated platelets facilitate hematogenous metastasis of breast cancer by modulating the PDGFR-β/COX-2 axis.
Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota.
Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus.
Protective Effects of ζ-Carotene-like Compounds against Acute UVB-Induced Skin Damage.
Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway.
GREM1, LRPPRC and SLC39A4 as potential biomarkers of intervertebral disc degeneration: a bioinformatics analysis based on multiple microarray and single-cell sequencing data.
Engineered Extracellular Vesicle-Delivered CRISPR/Cas9 for Radiotherapy Sensitization of Glioblastoma.
Robust Osteoconductive β-Tricalcium Phosphate/L-poly(lactic acid) Membrane via Orientation-Strengthening Technology.
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
HBx induced upregulation of FATP2 promotes the development of hepatic lipid accumulation.
m6A-mediated upregulation of miRNA-193a aggravates cardiomyocyte apoptosis and inflammatory response in sepsis-induced cardiomyopathy via the METTL3/ miRNA-193a/BCL2L2 pathway.
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
RIG-I promotes cell proliferation in esophageal squamous cell carcinoma by facilitating p21 degradation.
S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function.
Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis.
Knockdown of LINC00702 inhibits the growth and induces apoptosis of breast cancer through the Wnt/β-catenin pathway.
Prognostic value and immune infiltration of ARMC10 in pancreatic adenocarcinoma via integrated bioinformatics analyses.
In vitro Assessment of the Effects of Silybin on CYP2B6-mediated Metabolism.
The Comparation of Renal Anti-Senescence Effects and Blood Metabolites between Dapagliflozin and Metformin in Non-Diabetes Environment.
Histone deacetylase MrHos3 negatively regulates the production of citrinin and pigments in Monascus ruber.
Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation.
Evaluating anti-viral effect of Ivermectin on porcine epidemic diarrhea virus and analyzing the related genes and signaling pathway by RNA-seq in vitro.
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
Hsa-miR-27b-5p suppresses the osteogenic and odontogenic differentiation of stem cells from human exfoliated deciduous teeth via targeting BMPR1A: An ex vivo study.
The therapeutic value of adipose-derived pericyte transplantation after intracerebral hemorrhage in rats.
Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R.
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Interference KRT17 reverses doxorubicin resistance in triple-negative breast cancer cells by Wnt/β-catenin signaling pathway.
Inhibiting PI3K/Akt-Signaling Pathway Improves Neurobehavior Changes in Anti-NMDAR Encephalitis Mice by Ameliorating Blood-Brain Barrier Disruption and Neuronal Damage.
Hepatic transcriptome delineates the therapeutic effects of Sanren Tang on high-fat diet-induced non-alcoholic fatty liver disease.
Tenofovir disoproxil fumarate mediates neuronal injury by inducing neurotoxicity.
Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation.
Astragaloside IV-mediated inhibition of oxidative stress by upregulation of ghrelin in type 2 diabetes-induced cognitive impairment.
Silymarin ameliorates peritoneal fibrosis by inhibiting the TGF-β/Smad signaling pathway.
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Chelerythrine chloride inhibits the progression of colorectal cancer by targeting cancer-associated fibroblasts through intervention with WNT10B/β-catenin and TGFβ2/Smad2/3 axis.
Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase.
A peptidic network antibody inhibits both angiogenesis and inflammatory response.
Upregulation of miR-184 and miR-19a-3p induces endothelial dysfunction by targeting AGO2 in Kawasaki disease.
Human-Induced Hepatocytes-Derived Extracellular Vesicles Ameliorated Liver Fibrosis in Mice Via Suppression of TGF-β1/Smad Signaling and Activation of Nrf2/HO-1 Signaling.
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration.
Crosstalk of ferroptosis regulators and tumor immunity in pancreatic adenocarcinoma: novel perspective to mRNA vaccines and personalized immunotherapy.
Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway.
Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways.
The 3'‑untranslated region of XB130 regulates its mRNA stability and translational efficiency in non‑small cell lung cancer cells.
SALL1 promotes proliferation and metastasis and activates phosphorylation of p65 and JUN in colorectal cancer cells.
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
TMEM175 downregulation participates in impairment of the autophagy related lysosomal dynamics following neonatal hypoxic-ischemic brain injury.
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
EGFR suppression contributes to growth inhibitory activity of G-quadruplex ligands in non-small cell lung cancers.
Sulforaphene suppresses RANKL-induced osteoclastogenesis and LPS-induced bone erosion by activating Nrf2 signaling pathway.
Metformin Promotes Proliferation of Mouse Female Germline Stem Cells by Histone Acetylation Modification of Traf2.
Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway.
Intermittent fasting alleviates type 1 diabetes-induced cognitive dysfunction by improving the frontal cortical metabolic disorder.
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Cocktail of three isoquinoline alkaloids derived from Glaucium grandiflorum Boiss. & A. Huet subsp. refractum (Nábelek) Mory inhibits the production of LPS-induced ROS, pro-inflammatory cytokines, and mediators through the down-regulation of p38 MAPK in BV-2 cells.
High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast.
Regulatory mechanism of CaMKII δ mediated by RIPK3 on myocardial fibrosis and reversal effects of RIPK3 inhibitor GSK'872.
Caffeic acid's role in mitigating polycystic ovary syndrome by countering apoptosis and ER stress triggered by oxidative stress.
Photocurable 3D-Printed PMBG/TCP Scaffold Coordinated with PTH (1-34) Bidirectionally Regulates Bone Homeostasis to Accelerate Bone Regeneration.
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Xanthatin suppresses pancreatic cancer cell growth via the ROS/RBL1 signaling pathway: In vitro and in vivo insights.
Systemic pharmacology reveal the mechanism by which the Qiangjin Zhuanggu Qufeng mixture inhibits LPS-induced pyroptosis of rat nucleus pulposus cells.
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
Protective effect of TNIP2 on the inflammatory response of microglia after spinal cord injury in rats.
The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Tong Sai granule improves AECOPD via regulation of MAPK-SIRT1-NF-κB pathway and cellular senescence alleviation.
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer.
Discovery of novel thymidylate synthase (TS) inhibitors that influence cancer angiogenesis and metabolic reprogramming in NSCLC cells.
Proteostasis is differentially modulated by inhibition of translation initiation or elongation.
GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion.
Synergistic induction of apoptosis in liver cancer cells: exploring the combined potential of doxorubicin and XL-888.
A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.
Chick chorioallantoic membrane model to investigate role of migrasome in angiogenensis.
Anti-inflammatory effect of Lactiplantibacillus plantarum T1 cell-free supernatants through suppression of oxidative stress and NF-κB- and MAPK-signaling pathways.
α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity.
Enzymolysis-based RNA pull-down identifies YTHDC2 as an inhibitor of antiviral innate response.
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance.
BMP9 functions as a negative regulator in the myogenic differentiation of primary mouse myoblasts.
Chlorogenic Acid from Burdock Roots Ameliorates Oleic Acid-Induced Steatosis in HepG2 Cells through AMPK/ACC/CPT-1 Pathway.
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma.
BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas.
BMP7 alleviates trigeminal neuralgia by reducing oligodendrocyte apoptosis and demyelination.
A Therapeutic DNA Vaccine Targeting HPV16 E7 in Combination with Anti-PD-1/PD-L1 Enhanced Tumor Regression and Cytotoxic Immune Responses.
Effects of Insulin on Proliferation, Apoptosis, and Ferroptosis in Primordial Germ Cells via PI3K-AKT-mTOR Signaling Pathway.
Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis.
TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC.
[High expression of secretogranin II increases oxaliplatin resistance of colorectal cancer cells].
Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling.
CircMAPK9 promotes adipogenesis through modulating hsa-miR-1322/FTO axis in obesity.
Expression profiles and function prediction of tRNA-derived fragments in glioma.
IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions.
Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses.
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D(2) Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression.
Effects of Cinnamon Powder on Glucose Metabolism in Diabetic Mice and the Molecular Mechanisms.
African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation.
Identification of Potential Mechanisms of Rk1 Combination with Rg5 in the Treatment of Type II Diabetes Mellitus by Integrating Network Pharmacology and Experimental Validation.
CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis.
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
miR-103-3p Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2.
Comprehensive Transcriptomic Profiling of m6A Modification in Age-Related Hearing Loss.
The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma.
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.
Expression of TRPM8 in sheep reproductive tissues and brain areas important for the expression of reproductive behavior.
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.
Development of a Rare Earth Nanoprobe Enables In Vivo Real-Time Detection of Sentinel Lymph Node Metastasis of Breast Cancer Using NIR-IIb Imaging.
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Matrix stiffness induces Drp1-mediated mitochondrial fission through Piezo1 mechanotransduction in human intervertebral disc degeneration.
SNIP1 reduces extracellular matrix degradation and inflammation via inhibiting the NF-κB signaling pathway in osteoarthritis.
Metformin combined with glucose starvation synergistically suppress triple-negative breast cancer by enhanced unfolded protein response.
Dapagliflozin suppress endoplasmic reticulum stress mediated apoptosis of chondrocytes by activating Sirt1.
Chronic exposure to low-dose deltamethrin can lead to colon tissue injury through PRDX1 inactivation-induced mitochondrial oxidative stress injury and gut microbial dysbiosis.
Aluminum exposure induces central nervous system impairment via activating NLRP3-medicated pyroptosis pathway.
Endoplasmic reticulum-mitochondrial calcium transport contributes to soft extracellular matrix-triggered mitochondrial dynamics and mitophagy in breast carcinoma cells.
Clearance of Stress-Induced Premature Senescent Cells Alleviates the Formation of Abdominal Aortic Aneurysms.
Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression.
Protective effect of GLP-1 analog liraglutide on podocytes in mice with diabetic nephropathy.
Moutai Distiller's grains Polyphenol extracts and rutin alleviate DSS-induced colitis in mice: Modulation of gut microbiota and intestinal barrier function （R2）.
The extract from Portulaca oleracea L. rehabilitates skin photoaging via adjusting miR-138-5p/Sirt1-mediated inflammation and oxidative stress.
HuangQi ChiFeng decoction maintains gut microbiota and bile acid homeostasis through FXR signaling to improve atherosclerosis.
FBXL19 promotes malignant behaviours by activating MAPK signalling and negatively correlates with prognosis in hepatocellular carcinoma.
Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS- induced depression-like behaviors through downregulation of α2δ-1.
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
BMSCs alleviate liver cirrhosis by regulating Fstl1/Wnt/β-Catenin signaling pathway.
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.
Different Chronic Stress Paradigms Converge on Endogenous TDP43 Cleavage and Aggregation.
Ketamine counteracts sevoflurane-induced depressive-like behavior and synaptic plasticity impairments through the adenosine A2A receptor/ERK pathway in rats.
Macrophage Sult2b1 promotes pathological neovascularization in age-related macular degeneration.
Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway.
Pseudolaric acid B induces apoptosis associated with the mitochondrial and PI3K/AKT/mTOR pathways in triple‑negative breast cancer.
Pb inhibited C2C12 myoblast differentiation by regulating HDAC2.
LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90.
Melatonin attenuates cholestatic liver injury via inhibition of the inflammatory response.
MicroRNA-122-5p alleviates endometrial fibrosis via inhibiting the TGF-β/SMAD pathway in Asherman's syndrome.
Capsaicin functions as a selective degrader of STAT3 to enhance host resistance to viral infection.
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.
Human amnion-derived mesenchymal stem cells improve subclinical hypothyroidism by immunocompetence mediating apoptosis inhibition on thyroid cells in aged mice.
Role of interleukin-36γ induced by ultraviolet radiation in chronic actinic dermatitis.
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
The novel peptide DR4penA attenuates the bleomycin- and paraquat-induced pulmonary fibrosis by suppressing the TGF-β/Smad signaling pathway.
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Engineering CAR-NK cell derived exosome disguised nano-bombs for enhanced HER2 positive breast cancer brain metastasis therapy.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1α pathway.
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Periplaneta americana extract promotes osteoblast differentiation of human alveolar bone marrow mesenchymal stem cells.
UBE2C promotes malignancy of cutaneous squamous cell carcinoma.
Optimized infrared photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (IR-PAR-CLIP) protocol identifies novel IGF2BP3-interacting RNAs in colon cancer cells.
Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line chick.
Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.
SIRT6 mediated histone H3K9ac deacetylation involves myocardial remodelling through regulating myocardial energy metabolism in TAC mice.
Avicularin alleviates acute liver failure by regulation of the TLR4/MyD88/NF-κB and Nrf2/HO-1/GPX4 pathways to reduce inflammation and ferroptosis.
Extracellular vesicles from bone marrow mesenchymal stem cells alleviate osteoporosis in mice through USP7-mediated YAP1 protein stability and the Wnt/β-catenin pathway.
Selenium Deficiency via the ROS/NLRP3/IL-1β Signaling Pathway Leads to Pyroptosis Injury in Pig Spleen.
Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils.
Sulforaphane alleviates the meiosis defects induced by 3-nitropropionic acid in mouse oocytes.
In vitro acne disease model from inertial focusing effect for studying the interactions between sebocyte glands and macrophages.
High-intensity swimming alleviates nociception and neuroinflammation in a mouse model of chronic post-ischemia pain by activating the resolvin E1-chemerin receptor 23 axis in the spinal cord.
Dl-3-n-butylphthalide exerts neuroprotective effects by modulating hypoxia-inducible factor 1-alpha ubiquitination to attenuate oxidative stress-induced apoptosis.
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2.
Keratinocyte derived HMGB1 aggravates psoriasis dermatitis via facilitating inflammatory polarization of macrophages and hyperproliferation of keratinocyte.
Anti-resorption role of low-intensity pulsed ultrasound (LIPUS) during large-scale bone reconstruction using porous titanium alloy scaffolds through inhibiting osteoclast differentiation.
STAT1 suppresses the transcriptional activity of TRIM21 in gastric cancer.
PINK1-mediated mitophagy induction protects against preeclampsia by decreasing ROS and trophoblast pyroptosis.
Abamectin induced brain and liver toxicity in carp: The healing potential of silybin and potential molecular mechanisms.
Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors.
Involvement of iNOS-induced reactive enteric glia cells in gastrointestinal motility disorders of postoperative Ileus mice.
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages.
Melatonin exerts a protective effect in ameliorating nephrolithiasis via targeting AMPK/PINK1-Parkin mediated mitophagy and inhibiting ferroptosis in vivo and in vitro.
miR-214 could promote myocardial fibrosis and cardiac mesenchymal transition in VMC mice through regulation of the p53 or PTEN-PI3K-Akt signali pathway, promoting CF proliferation and inhibiting its ng pathway.
The efficacy and mechanism of Angelica sinensis (Oliv.) Diels root aqueous extract based on RNA sequencing and 16S rDNA sequencing in alleviating polycystic ovary syndrome.
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma.
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
Chitobiose exhibited a lipid-lowering effect in ob/ob(-/-) mice via butyric acid enrolled liver-gut crosstalk.
WISP1 Is Involved in the Pathogenesis of Kashin-Beck Disease via the Autophagy Pathway.
Role of steroid receptor-associated and regulated protein in tumor progression and progesterone receptor signaling in endometrial cancer.
Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function.
DHA and EPA inhibit porcine coronavirus replication by alleviating ER stress.
Hypoxia and HIF-1α promote lytic de novo KSHV infection.
Effective-compound combination of Bufei Yishen formula III combined with ER suppress airway mucus hypersecretion in COPD rats: via EGFR/MAPK signaling.
Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer.
Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.
Inhibition of Ferroptosis Ameliorates Photoreceptor Degeneration in Experimental Diabetic Mice.
SHED-derived exosomes attenuate trigeminal neuralgia after CCI of the infraorbital nerve in mice via the miR-24-3p/IL-1R1/p-p38 MAPK pathway.
Lysyl oxidase inhibits BMP9-induced osteoblastic differentiation through reducing Wnt/β-catenin via HIF-1a repression in 3T3-L1 cells.
Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway.
Role of LncMALAT1-miR-141-3p/200a-3p-NRXN1 Axis in the Impairment of Learning and Memory Capacity in ADHD.
Lactoferrin Alleviates Ethanol-Induced Injury via Promoting Nrf2 Nuclear Translocation in BRL-3A Rat Liver Cells.
Micronano Titanium Accelerates Mesenchymal Stem Cells Aging through the Activation of Senescence-Associated Secretory Phenotype.
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
Scleral remodeling in early adulthood: the role of FGF-2.
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival.
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
FARSB Facilitates Hepatocellular Carcinoma Progression by Activating the mTORC1 Signaling Pathway.
Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation.
Cell-based screen identifies porphyrins as FGFR3 activity inhibitors with therapeutic potential for achondroplasia and cancer.
The role of miRNA-144-3p/Oprk1/KOR in nicotine dependence and nicotine withdrawal in male rats.
The cellular trajectories of tumor-associated macrophages decipher the heterogeneity of pancreatic cancer.
A prognostic risk model for programmed cell death and revealing TRIB3 as a promising apoptosis suppressor in renal cell carcinoma.
Chlorogenic Acid Alleviated AFB1-Induced Hepatotoxicity by Regulating Mitochondrial Function, Activating Nrf2/HO-1, and Inhibiting Noncanonical NF-κB Signaling Pathway.
High-intensity interval training alleviates exhaustive exercise-induced HSP70-assisted selective autophagy in skeletal muscle.
Immunological characteristics of immunogenic cell death genes and malignant progression driving roles of TLR4 in anaplastic thyroid carcinoma.
m6A methyltransferase METTL3 contributes to sympathetic hyperactivity post-MI via promoting TRAF6-dependent mitochondrial ROS production.
SERPINE1 and SERPINB7 as potential biomarkers for intravenous vitamin C treatment in non-small-cell lung cancer.
Exosomes derived from cardiac fibroblasts with angiotensin II stimulation provoke hypertrophy and autophagy inhibition in cardiomyocytes.
Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway.
MiR-184 targeting FOXO1 regulates host-cell oxidative stress induced by Chlamydia psittaci via the Wnt/β-catenin signaling pathway.
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions.
USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase separation potential.
Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy.
COL10A1 promotes tumorigenesis by modulating CD276 in pancreatic adenocarcinoma.
Inhibition of Galectin-1 attenuates lung fibroblast activation and proliferation in lung fibrosis.
Dimethyl fumarate attenuates cholestatic liver injury by activating the NRF2 and FXR pathways and suppressing NLRP3/GSDMD signaling in mice.
Activation of the Nrf-2 pathway by pinocembrin safeguards vertebral endplate chondrocytes against apoptosis and degeneration caused by oxidative stress.
Exploring the effect and mechanism of Haizao Yuhu decoction containing three variants of glycyrrhiza on goiter using an integrated strategy of network pharmacology and RNA sequencing.
Network pharmacology-based approach uncovers the pharmacodynamic components and mechanism of Fructus Tribuli for improving endothelial dysfunction in hypertension.
Potential 'anti-cancer' effects of esketamine on proliferation, apoptosis, migration and invasion in esophageal squamous carcinoma cells.
RhoA suppresses pseudorabies virus replication in vitro.
Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth.
Grid2 interacting protein is a potential biomarker related to immune infiltration in colorectal cancer.
Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins.
NeuroD1 administration ameliorated neuroinflammation and boosted neurogenesis in a mouse model of subarachnoid hemorrhage.
In situ visualization of m6A sites in cellular mRNAs.
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Low-intensity ultrasound combined with arsenic trioxide induced apoptosis of glioma via EGFR/AKT/mTOR.
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Carbamazepine regulates USP10 through miR-20a-5p to affect the deubiquitination of SKP2 and inhibit osteogenic differentiation.
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Sevoflurane Preconditioning Alleviates Posttraumatic Stress Disorder-Induced Apoptosis in the Hippocampus via the EZH2-Regulated Akt/mTOR Axis and Improves Synaptic Plasticity.
Enhanced Hypoglycemic Bioactivity via RAS/Raf-1/MEK/ERK Signaling Pathway by Combining Capsaicin and QUERCETIN from Chili Peppers.
Inhibition of endogenous hydrogen sulfide production suppresses the growth of nasopharyngeal carcinoma cells.
A novel lncRNA 495810 promotes the aerobic glycolysis in colorectal cancer by stabilizing pyruvate kinase isozyme M2.
BML-111 inhibits osteoclast differentiation by suppressing the MAPK and NF-κB pathways, alleviating deterioration of the knee joints in a CIA rat model.
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Comparative study of cigarette smoke, Klebsiella pneumoniae, and their combination on airway epithelial barrier function in mice.
A novel mechanism of cannabidiol in suppressing ovarian cancer through LAIR-1 mediated mitochondrial dysfunction and apoptosis.
Decreased DANCR contributes to high glucose-induced extracellular matrix accumulation in human renal mesangial cell via regulating the TGF-β/Smad signaling.
Mesenchymal stem cell exosomes as nanotherapeutics for dry age-related macular degeneration.
EIF4A3-induced circular RNA SCAP facilitates tumorigenesis and progression of non-small-cell lung cancer via miR-7/SMAD2 signaling.
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Methionine alleviates heat stress-induced ferroptosis in bovine mammary epithelial cells through the Nrf2 pathway.
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Pioglitazone can improve liver sex hormone-binding globulin levels and lipid metabolism in polycystic ovary syndrome by regulating hepatocyte nuclear factor-4α.
Periplocin targets low density lipoprotein receptor-related protein 4 to attenuate osteoclastogenesis and protect against osteoporosis.
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Berberine attenuates sunitinib-induced cardiac dysfunction by normalizing calcium regulation disorder via SGK1 activation.
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Prophylactic effect of Tongxieyaofang polysaccharide on depressive behavior in adolescent male mice with chronic unpredictable stress through the microbiome-gut-brain axis.
Identification of MAP Kinase Kinase 3 as a protein target of myricetin in non-small cell lung cancer cells.
Epigallocatechin-3-gallate (EGCG) based metal-polyphenol nanoformulations alleviates chondrocytes inflammation by modulating synovial macrophages polarization.
SMURF1 inhibits the Th17 and Th17.1 polarization and improves the Treg/Th17 imbalance in systemic lupus erythematosus through the ubiquitination of RORγt.
Design, synthesis and bioevaluation of 1,2,4-thiadiazolidine-3,5-dione derivatives as potential GSK-3β inhibitors for the treatment of Alzheimer's disease.
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A-YTHDF2-dependent manner.
Sulfotransferase 1C2 promotes hepatocellular carcinoma progression by enhancing glycolysis and fatty acid metabolism.
Intrafibrillar Mineralization and Immunomodulatory for Synergetic Enhancement of Bone Regeneration via Calcium Phosphate Nanocluster Scaffold.
Eriocitrin attenuates sepsis-induced acute lung injury in mice by regulating MKP1/MAPK pathway mediated-glycolysis.
MiR-223-3p regulates the eosinophil degranulation and enhances the inflammation in allergic rhinitis by targeting FBXW7.
Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation.
XinLi formula, a traditional Chinese decoction, alleviates chronic heart failure via regulating the interaction of AGTR1 and AQP1.
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
Spatiotemporal Characterization of Human Early Intervertebral Disc Formation at Single-Cell Resolution.
Overexpression of Podoplanin Predicts Poor Prognosis in Patients With Glioma.
Structure-guided identification of novel dual-targeting estrogen receptor α degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer.
Natural Compounds, Optimal Combination of Brusatol and Polydatin Promote Anti-Tumor Effect in Breast Cancer by Targeting Nrf2 Signaling Pathway.
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
The Host Protein CAD Regulates the Replication of FMDV through the Function of Pyrimidines' De Novo Synthesis.
Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43.
Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1.
Transcriptional coactivation by EHMT2 restricts glucocorticoid-induced insulin resistance in a study with male mice.
A Potential Adhesin/Invasin STM0306 Participates in Host Cell Inflammation Induced by Salmonella enterica Serovar Typhimurium.
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
Integrated pan-cancer analysis of centromere protein F and experimental verification of its role and clinical significance in cholangiocarcinoma.
Pyroptosis of Macrophages Induced by Clostridium perfringens Beta-1 Toxin.
Impairment of rigidity sensing caused by mutant TP53 gain of function in osteosarcoma.
Development and validation of a novel T cell proliferation-related prognostic model for predicting survival and immunotherapy benefits in melanoma.
BESST: a novel LncRNA knockout strategy with less genome perturbance.
Hairy gene homolog increases nasopharyngeal carcinoma cell stemness by upregulating Bmi-1.
Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis.
CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer.
An ankylosing spondylitis risk variant alters osteoclast differentiation.
Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
Mitochondrial impairment and downregulation of Drp1 phosphorylation underlie the antiproliferative and proapoptotic effects of alantolactone on oral squamous cell carcinoma cells.
Regulatory Effects of FGF9 on Dermal Papilla Cell Proliferation in Small-Tailed Han Sheep.
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
A New Method for Programmable RNA Editing Using CRISPR Effector Cas13X.1.
Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines.
Esketamine ameliorates post-stroke anxiety by modulating microglial HDAC3/NF-κB/COX1 inflammatory signaling in ischemic cortex.
Osthole relieves skin damage and inhibits chronic itch through modulation of Akt/ZO-3 pathway in atopic dermatitis.
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury.
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway.
Persistent Degradation of HER2 Protein by Hybrid nanoPROTAC for Programmed Cell Death.
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Integrative multi-omics and drug-response characterization of patient-derived prostate cancer primary cells.
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Interferon regulatory factor 4 deletion protects against kidney inflammation and fibrosis in deoxycorticosterone acetate/salt hypertension.
The circadian rhythm gene Bmal1 ameliorates acute deoxynivalenol-induced liver damage.
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins.
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome.
Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1.
Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt-GSK-3β-Nrf2 pathway.
Oral administration of Lactobacillus plantarum JC7 alleviates OVA-induced murine food allergy through immunoregulation and restoring disordered intestinal microbiota.
Regulation of telomere silencing by the core histones-autophagy-Sir2 axis.
Regulation of BCRP expression and sulfasalazine pharmacokinetics by the nuclear receptor REV-ERBα.
The effect of occlusal disharmony on a chronic stress-induced animal model of gut microbiota dysbiosis.
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis.
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing.
A gene-encoded FRET fluorescent sensor designed for detecting asymmetric dimethylation levels in vitro and in living cells.
CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.
CircTNPO3 promotes hepatocellular carcinoma progression by sponging miR-199b-5p and regulating STRN expression.
MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335-5p signaling pathway.
GPX4 utilization by selenium is required to alleviate cadmium-induced ferroptosis and pyroptosis in sheep kidney.
PLAGL2 promotes the stemness and is upregulated by transcription factor E2F1 in human lung cancer.
OASL knockdown inhibits the progression of stomach adenocarcinoma by regulating the mTORC1 signaling pathway.
MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.
Glycogen synthesis kinase-3β involves in the analgesic effect of liraglutide on diabetic neuropathic pain.
RAGE signaling pathway is involved in CUS-induced depression-like behaviors by regulating the expression of NR2A and NR2B in rat hippocampus DG.
Resveratrol reversed ambient particulate matter exposure-perturbed oscillations of hepatic glucose metabolism by regulating SIRT1 in mice.
Age-related liver endothelial zonation triggers steatohepatitis by inactivating pericentral endothelium-derived C-kit.
PPP1R14B is a diagnostic prognostic marker in patients with uterine corpus endometrial carcinoma.
LINC01012 upregulation promotes cervical cancer proliferation and migration via downregulation of CDKN2D.
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.
Antiviral activity of the HSP90 inhibitor VER-50589 against enterovirus 71.
METTL3 alleviates D-gal-induced renal tubular epithelial cellular senescence via promoting miR-181a maturation.
Exposure to Fluoride From in Utero to Puberty Alters Gonadal Structure and Steroid Hormone Expression in Offspring Rats.
High concentrate diet induced inflammatory response and tight junction disruption in the mammary gland of dairy cows.
On-target inhibition of Cryptosporidium parvum by nitazoxanide (NTZ) and paclitaxel (PTX) validated using a novel MDR1-transgenic host cell model and algorithms to quantify the effect on the parasite target.
PTEN Deficiency Facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis.
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of (AGTR1+) CAFs in intrahepatic cholangiocarcinoma.
ESE1/AGR2 axis antagonizes TGF-β-induced epithelial-mesenchymal transition in low-grade pancreatic cancer.
hsa-mir-133a-2 promotes the proliferation and invasion of cervical cancer cells by targeting the LAMB3-mediated PI3K/ATK pathway.
NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss.
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
TNFα stimulates the proliferation of immature Sertoli cells by attenuating UPS-degradation of cyclin D1 and leads to the delay of BTB maturation in pubertal rats.
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.
The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia.
miR-330-3p alleviates the progression of atherosclerosis by downregulating AQP9.
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors.
Roles of glutathione peroxidase 4 on the mercury-triggered ferroptosis in renal cells: implications for the antagonism between selenium and mercury.
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Exosome-laden injectable self-healing hydrogel based on quaternized chitosan and oxidized starch attenuates disc degeneration by suppressing nucleus pulposus senescence.
ADCY9 functions as a novel cancer suppressor gene in lung adenocarcinoma.
Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling.
Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy.
CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation.
Antihepatoma peptide, scolopentide, derived from the centipede scolopendra subspinipes mutilans.
Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy.
Notch-RBPJ Pathway for the Differentiation of Bone Marrow Mesenchymal Stem Cells in Femoral Head Necrosis.
BaoShenTongLuo formula protects against podocyte injury by regulating AMPK-mediated mitochondrial biogenesis in diabetic kidney disease.
SLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling.
Scutellarin prevents acute alcohol-induced liver injury via inhibiting oxidative stress by regulating the Nrf2/HO-1 pathway and inhibiting inflammation by regulating the AKT, p38 MAPK/NF-κB pathways.
ZNF582 overexpression restrains the progression of clear cell renal cell carcinoma by enhancing the binding of TJP2 and ERK2 and inhibiting ERK2 phosphorylation.
ZFP281 coordinates DNMT3 and TET1 for transcriptional and epigenetic control in pluripotent state transitions.
The Expression Pattern of tRNA-Derived Small RNAs in Adult Drosophila and the Function of tRF-Trp-CCA-014-H3C4 Network Analysis.
GAS-STING signaling plays an essential pathogenetic role in Doxorubicin-Induced Cardiotoxicity.
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling.
Low-Carbohydrate Diet Modulates Glucose-Lipid Utilization in Skeletal Muscle of Diabetic Mice.
Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway.
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
[Wine-processed Chuanxiong Rhizoma enhances efficacy of aumolertinib against EGFRmutant non-small cell lung cancer xenografts in nude mouse brain].
Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.
Comparative landscape of genetic dependencies in human and chimpanzee stem cells.
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
Myeloid TLR4 signaling promotes post-injury withdrawal resolution of murine liver fibrosis.
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
HPF Modulates the Differentiation of BMSCs into HLCs and Promotes the Recovery of Acute Liver Injury in Mice.
NDFIP1 limits cellular TAZ accumulation via exosomal sorting to inhibit NSCLC proliferation.
Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities.
ANXA2 as a novel substrate of FBXW7 promoting esophageal squamous cell carcinoma via ERK phosphorylation.
Transcriptional activation of CSTB gene expression by transcription factor Sp3.
Bicuculline and Bumetanide Attenuate Sevoflurane-Induced Impairment of Myelination and Cognition in Young Mice.
MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors' Efficacy in Neuroblastoma Cells.
ncRNAs-mediated overexpression of STIL predict unfavorable prognosis and correlated with the efficacy of immunotherapy of hepatocellular carcinoma.
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
Glyphosate-triggered hepatocyte ferroptosis via suppressing Nrf2/GSH/GPX4 axis exacerbates hepatotoxicity.
Ring finger protein 10 improves pirarubicin-induced cardiac inflammation by regulating the AP-1/Meox2 signaling pathway.
Berbamine dihydrochloride suppresses the progression of colorectal cancer via RTKs/Akt axis.
Explore bioactive ingredients and potential mechanism of Houpo Mahuang decoction for chronic bronchitis based on UHPLC-Q exactive orbitrap HRMS, network pharmacology, and experiment verification.
Integrating metabolomics and network pharmacology to investigate Panax japonicus prevents kidney injury in HFD/STZ-induced diabetic mice.
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
A Novel TrxR1 Inhibitor Regulates NK and CD8+ T Cell Infiltration and Cytotoxicity, Enhancing the Efficacy of Anti-PD-1 Immunotherapy against Hepatocarcinoma.
Ultrasound-mediated mesoporous silica nanoparticles loaded with PDLIM5 siRNA inhibit gefitinib resistance in NSCLC cells by attenuating EMT.
Mrhst4 gene, coding for NAD+-dependent deacetylase is involved in citrinin production of Monascus ruber.
25-hydroxycholesterol inhibits human papillomavirus infection in cervical epithelial cells by perturbing cytoskeletal remodeling.
AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin.
Effect of isorhamnetin on carbonic anhydrase IX expression and tumorigenesis of bladder cancer by activating PPARγ/PTEN/AKT pathway.
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Effects of prolonged stimulation with heated tobacco products (Ploom TECH(+) ) on gingival epithelial cells.
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
A Study on the Role of Wip1 in Renal Fibrosis by Modulating Macrophage Phenotype.
taVNS Alleviates Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Via Activating Basal Forebrain Cholinergic Neurons.
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy.
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.
1,25-Dihydroxvitamin D3 attenuates the damage of human immortalised keratinocytes caused by Ultraviolet-B.
Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p.
Baicalin ameliorates high fat diet-induced nonalcoholic fatty liver disease in mice via adenosine monophosphate-activated protein kinase-mediated regulation of SREBP1/Nrf2/NF-κB signaling pathways.
Characterization of the Roles of Suppressor of Cytokine Signaling-3 in Esophageal Carcinoma.
Targeting HDAC11 activity by FT895 restricts EV71 replication.
Tranexamic acid may promote melanocores clustering in keratinocytes through upregulation of Rab5b.
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Bifidobacterium promotes retinal ganglion cell survival by regulating the balance of retinal glial cells.
Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD.
Myo-Inositol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy by Inhibiting PI3K/AKT Activation.
Architecture and dynamics of a desmosome-endoplasmic reticulum complex.
1,4,5,6,7,8‑Hexahydropyrido[4,3‑d]pyrimidine inhibits HepG2 cell proliferation, migration and invasion, and induces apoptosis through the upregulation of miR‑26b‑5p by targeting CDK8.
Ameliorative Effects of Extracellular Vesicles Derived from Mesenchymal Stem Cells on Apoptosis and Differentiation of Osteoblasts Treated with CoCl(2).
The mechanism of acid resistance by ornithine decarboxylase in Trichinella spiralis.
Jinyinqingre Oral Liquid alleviates LPS-induced acute lung injury by inhibiting the NF-κB/NLRP3/GSDMD pathway.
A Silver Compound with Potential Applications as an Anticancer, Antibacterial, Antifungal, and Anti-Alzheimer's Agent.
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Polydopamine-cladded montmorillonite micro-sheets as therapeutic platform repair the gut mucosal barrier of murine colitis through inhibiting oxidative stress.
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma.
Exosomes derived from mesenchymal stromal cells promote bone regeneration by delivering miR-182-5p-inhibitor.
Tailor-Made Autophagy Cascade Amplification Polymeric Nanoparticles for Enhanced Tumor Immunotherapy.
Vancomycin Pretreatment on MPTP-Induced Parkinson's Disease Mice Exerts Neuroprotection by Suppressing Inflammation Both in Brain and Gut.
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress.
Mitoquinone ameliorated airway inflammation by stabilizing β-catenin destruction complex in a steroid-insensitive asthma model.
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
Ginsenoside Rh4 inhibits breast cancer growth through targeting histone deacetylase 2 to regulate immune microenvironment and apoptosis.
Smad3-mediated lncRNA HSALR1 enhances the non-classic signalling pathway of TGF-β1 in human bronchial fibroblasts by binding to HSP90AB1.
Discovery of novel exceptionally potent and orally active c-MET PROTACs for the treatment of tumors with MET alterations.
Hypoxic lung adenocarcinoma-derived exosomal miR-1290 induces M2 macrophage polarization by targeting SOCS3.
Parthenolide targets NLRP3 to treat inflammasome-related diseases.
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
T52 attenuates oncogenic STAT3 signaling and suppresses osteosarcoma.
Isoliquiritigenin inhibits virus replication and virus-mediated inflammation via NRF2 signaling.
Ellagic acid inhibits CDK12 to increase osteoblast differentiation and alleviate osteoporosis in hindlimb-unloaded and ovariectomized mice.
KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway.
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
Inhibition of CPEB3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs, and enhances object location memory.
The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study.
Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Curcumin Attenuates Periodontal Injury via Inhibiting Ferroptosis of Ligature-Induced Periodontitis in Mice.
MicroRNA-29a-3p prevents Schistosoma japonicum-induced liver fibrosis by targeting Roundabout homolog 1 in hepatic stellate cells.
Lycopene ameliorates islet function and down-regulates the TLR4/MyD88/NF-κB pathway in diabetic mice and Min6 cells.
LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma.
PACAP6-38 improves nitroglycerin-induced central sensitization by modulating synaptic plasticity at the trigeminal nucleus caudalis in a male rat model of chronic migraine.
Risk signature identification and NPRL2 affects sunitinib sensitivity in clear cell renal cell carcinoma.
Aspartoacylase promotes the process of tumour development and is associated with immune infiltrates in gastric cancer.
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Carbonic anhydrase IX inhibitor S4 triggers release of DAMPs related to immunogenic cell death in glioma cells via endoplasmic reticulum stress pathway.
Neurokinin-1 receptor drives PKCɑ-AURKA/N-Myc signaling to facilitate the neuroendocrine progression of prostate cancer.
Panaxytriol upregulates CYP3A4 expression through the interaction between nuclear regulators and DNA response elements.
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8(+) T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition.
Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis.
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
ICP4-Associated Activation of Rap1b Facilitates Herpes Simplex Virus Type I (HSV-1) Infection in Human Corneal Epithelial Cells.
Identification of TIMP1 as an inflammatory biomarker associated with temporal lobe epilepsy based on integrated bioinformatics and experimental analyses.
Identification of potential biomarkers for idiopathic pulmonary fibrosis and validation of TDO2 as a potential therapeutic target.
S-Palmitoylation of the serotonin transporter promotes its cell surface expression and serotonin uptake.
Synergism Antiproliferative Effects of Apigenin and Naringenin in NSCLC Cells.
METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing.
Syntabulin regulates neuronal excitation/inhibition balance and epileptic seizures by transporting syntaxin 1B.
TNIP2 inhibits amyloidogenesis by regulating the 3'UTR of BACE1: An in vitro study.
Histone Deacetylase Inhibition and Autophagy Modulation Induces a Synergistic Antiproliferative Effect and Cell Death in Cholangiocarcinoma Cells.
Microcystin-LR-Exposure-Induced Kidney Damage by Inhibiting MKK6-Mediated Mitophagy in Mice.
SMYD2 inhibition-mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity.
An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay.
A novel co-target of ACY1 governing plasma membrane translocation of SphK1 contributes to inflammatory and neuropathic pain.
Antioxidant Peptides from Monkfish Swim Bladders: Ameliorating NAFLD In Vitro by Suppressing Lipid Accumulation and Oxidative Stress via Regulating AMPK/Nrf2 Pathway.
Genetically Encoded Aminocoumarin Lysine for Optical Control of Protein-Nucleotide Interactions in Zebrafish Embryos.
Mettl3-mediated m(6)A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Trim65 attenuates isoproterenol-induced cardiac hypertrophy by promoting autophagy and ameliorating mitochondrial dysfunction via the Jak1/Stat1 signaling pathway.
Baicalin inhibited both the Furin/TGFβ1/Smad3/TSP-1 pathway in endothelial cells and the AKT/Ca(2+)/ROS pathway in platelets to ameliorate inflammatory coagulopathy.
Thallium exposure induces changes in B and T cell generation in mice.
A multi-bioresponsive self-assembled nano drug delivery system based on hyaluronic acid and geraniol against liver cancer.
Cigarette smoke triggers calcium overload in mouse hippocampal neurons via the ΔFOSB-CACNA2D1 axis to impair cognitive performance.
Perfluoroalkyl substances promote breast cancer progression via ERα and GPER mediated PI3K/Akt and MAPK/Erk signaling pathways.
Young Sca-1(+) bone marrow stem cell-derived exosomes preserve visual function via the miR-150-5p/MEKK3/JNK/c-Jun pathway to reduce M1 microglial polarization.
Disinhibition of Mesolimbic Dopamine Circuit by the Lateral Hypothalamus Regulates Pain Sensation.
cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8(+) T cell function and anti-tumor immunity.
Sparganii Rhizoma alleviates pulmonary fibrosis by inhibiting fibroblasts differentiation and epithelial-mesenchymal transition mediated by TGF-β1/ Smad2/3 pathway.
Phase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Blunting ROS/TRPML1 pathway protects AFB1-induced porcine intestinal epithelial cells apoptosis by restoring impaired autophagic flux.
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.
Proteomics reveals defective peroxisomal fatty acid oxidation during the progression of acute kidney injury and repair.
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes.
TEA Domain Transcription Factor 1 Inhibits Ferroptosis and Sorafenib Sensitivity of Hepatocellular Carcinoma Cells.
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
LATS-regulated nuclear-cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial-mesenchymal transition.
Ubiquitin ligase MARCH8 promotes the malignant progression of hepatocellular carcinoma through PTEN ubiquitination and degradation.
Long noncoding RNA MAPKAPK5-AS1 promotes metastasis through regulation miR-376b-5p/ECT2 axis in hepatocellular carcinoma.
Molecular characterization of wild-type and HSAN2B-linked FAM134B.
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Enhancement of CAR-T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins.
Lysophosphatidylcholine facilitates the pathogenesis of psoriasis through activating keratinocytes and T cells differentiation via glycolysis.
Erythropoietin ameliorates cognitive dysfunction in mice with type 2 diabetes mellitus via inhibiting iron overload and ferroptosis.
Direct Knockdown of PDZ and LIM Domain 1 Using an Adenoviral Delivery System Accelerates Osteogenesis and Fracture Healing in Mice.
Cathepsin B S-nitrosylation promotes ADAR1-mediated editing of its own mRNA transcript via an ADD1/MATR3 regulatory axis.
NKAP acts with HDAC3 to prevent R-loop associated genome instability.
African swine fever virus pS273R antagonizes stress granule formation by cleaving the nucleating protein G3BP1 to facilitate viral replication.
Co-phase separation of Y14 and RNA in vitro and its implication for DNA repair.
Periostin regulates LPS-induced apoptosis via Nrf2/HO-1 pathway in periodontal ligament fibroblasts.
Sialin mediates submandibular gland regeneration ability by affecting polysialic acid synthesis.
Transforming acidic coiled-coil containing protein 3 suppresses influenza A virus replication by impeding viral endosomal trafficking and nuclear import.
ORP5 promotes migration and invasion of cervical cancer cells by inhibiting endoplasmic reticulum stress.
Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells.
Analysis and validation of the potential of the MYO1E gene in pancreatic adenocarcinoma based on a bioinformatics approach.
Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis.
The prognostic value of DAAM2 in lower grade glioma, liver cancer, and breast cancer.
Host factor DUSP5 potently inhibits dengue virus infection by modulating cytoskeleton rearrangement.
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Oncogenic BRAF(V600E) induces microglial proliferation through extracellular signal-regulated kinase and neuronal death through c-Jun N-terminal kinase.
Novel antiosteoporotic peptides purified from protein hydrolysates of taihe black-boned silky fowl: By larval zebrafish model and molecular docking.
The Apelin/APJ system modulates seizure activity and endocytosis of the NMDA receptor GluN2B subunit.
Tissue Inhibitor of Metalloproteinase-1 Enhances Eosinophilic Airway Inflammation in Severe Asthma.
Knockdown of Cadherin 26 Prevents the Inflammatory Responses of Allergic Rhinitis.
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
Tongue-Brain-Transported ZnO Nanoparticles Induce Abnormal Taste Perception.
Myricetin improves pathological changes in 3×Tg-AD mice by regulating the mitochondria-NLRP3 inflammasome-microglia channel by targeting P38 MAPK signaling pathway.
Functional recovery of myocardial infarction by specific EBP-PR1P peptides bridging injectable cardiac extracellular matrix and vascular endothelial growth factor.
Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response.
Targeting L-Selectin Lymphocytes to Deliver Immunosuppressive Drug in Lymph Nodes for Durable Multiple Sclerosis Treatment.
Targeting Autophagy With the Synergistic Combination of Chloroquine and Rapamycin as a Novel Effective Treatment for Well-differentiated Liposarcoma.
Glucose-induced CRL4(COP1)-p53 axis amplifies glycometabolism to drive tumorigenesis.
Comparative landscape of genetic dependencies in human and chimpanzee stem cells.
Fibrin glue delivery system containing rhein ameliorates intervertebral disc degeneration by anti-inflammatory efficacy.
High-throughput identification of regulatory elements and functional assays to uncover susceptibility genes for nasopharyngeal carcinoma.
DSPE-PEG polymer enhanced berberine absorption specifically in the small intestine of rats through paracellular passway.
Expression and Activity of the Transcription Factor CCAAT/Enhancer-Binding Protein β (C/EBPβ) Is Regulated by Specific Pulse-Modulated Radio Frequencies in Oligodendroglial Cells.
FTO-dependent m(6)A regulates muscle fiber remodeling in an NFATC1-YTHDF2 dependent manner.
Development of Woolly Hair and Hairlessness in a CRISPR-Engineered Mutant Mouse Model with KRT71 Mutations.
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
LHPP suppresses proliferation, migration, and invasion in hepatocellular carcinoma and pancreatic cancer by inhibiting EGFR signaling pathway.
Ginsenoside-Rg1 synergized with voluntary running exercise protects against glial activation and dysregulation of neuronal plasticity in depression.
Multi-omics reveals that green pea (Pisum sativum L.) hull supplementation ameliorates non-alcoholic fatty liver disease via the SHMT2/glycine/mTOR/PPAR-γ signaling pathway.
Sulforaphane protects microvascular endothelial cells in lower limb ischemia/reperfusion injury mice.
Flavinated SDHA Underlies the Change in Intrinsic Optical Properties of Oral Cancers.
TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.
Silencing of UTX Mitigates Aging-Associated Cardiac Fibrosis via Blocking Cardiac Fibroblasts-to-Myofibroblasts Trans-Differentiation.
A simple and available measurement of onco-sEV dsDNA to protein ratio as a potential tumor marker.
Astaxanthin alleviates lipopolysaccharide-induced acute lung injury by suppressing ferroptosis.
TLR4 Overexpression Aggravates Bacterial Lipopolysaccharide-Induced Apoptosis via Excessive Autophagy and NF-κB/MAPK Signaling in Transgenic Mammal Models.
NPC1-dependent alterations in K(V)2.1-Ca(V)1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease.
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
DNA framework-engineered chimeras platform enables selectively targeted protein degradation.
The pharmacological mechanism of β-elemene in the treatment of esophageal cancer revealed by network pharmacology and experimental verification.
Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.
NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer.
Mixed-Lineage Leukemia 1 Inhibition Enhances the Differentiation Potential of Bovine Embryonic Stem Cells by Increasing H3K4 Mono-Methylation at Active Promoters.
Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Fufang Shenhua tablet inhibits renal fibrosis by inhibiting PI3K/AKT.
Luteolin inhibits subretinal fibrosis and epithelial-mesenchymal transition in laser-induced mouse model via suppression of Smad2/3 and YAP signaling.
Hypoxia-based classification and prognostic signature for clinical management of hepatocellular carcinoma.
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Cold exposure protects against medial arterial calcification development via autophagy.
PPARα is involved in high-fat diet-induced risk avoidance impairment via the regulation of hippocampal BDNF.
Target Discovery of Matrine against PRRSV in Marc-145 Cells via Activity-Based Protein Profiling.
A comparative study of the neuroprotective effects of dl-3-n-butylphthalide and edaravone dexborneol on cerebral ischemic stroke rats.
Resveratrol inhibits autophagy against myocardial ischemia-reperfusion injury through the DJ-1/MEKK1/JNK pathway.
Recombinant human neuregulin-1 alleviates immobilization-induced neuromuscular dysfunction via neuregulin-1/ErbB signaling pathway in rat.
Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.
Antidepressant effects of repeated s-ketamine administration as NMDAR Antagonist: Involvement of CaMKIIα and mTOR signaling in the hippocampus of CUMS mice.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation.
A novel cuproptosis-related diagnostic gene signature and differential expression validation in atherosclerosis.
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis.
Sodium Butyrate Ameliorates Deoxynivalenol-Induced Oxidative Stress and Inflammation in the Porcine Liver via NR4A2-Mediated Histone Acetylation.
Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability.
USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis.
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer's disease.
Hedgehog signaling is a potential therapeutic target for vascular calcification.
Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation to drive HCC.
ATAXIA TELANGIECTASIA MUTATED PROTECTS AGAINST LIPOPOLYSACCARIDE-INDUCED BLOOD-BRAIN BARRIER DISRUPTION BY REGULATING ATK/DRP1-MEDIATED MITOCHONDRIAL HOMEOSTASIS.
NF-κB pathway affects silica nanoparticle-induced fibrosis via inhibited inflammatory response and epithelial-mesenchymal transition in 3D co-culture.
A high-fat diet increases hepatic mitochondrial turnover through restricted acetylation in a NAFLD mouse model.
Implications of ferroptosis in silver nanoparticle-induced cytotoxicity of macrophages.
Cataract-causing variant Q70P damages structural stability of βB1-crystallin and increases its tendency to form insoluble aggregates.
Xanthine oxidase, a therapeutic target of realgar for non-small cell lung cancer.
Interleukin-19 upregulates fibronectin and collagen I expression via the NF-κB-Smad2/3 pathway in fibroblasts of patients with chronic rhinosinusitis.
CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau.
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
The expression and significance of long non-coding RNA ITGB2-AS1 in renal clear cell carcinoma.
IL-6/Stat3 suppresses osteogenic differentiation in ossification of the posterior longitudinal ligament via miR-135b-mediated BMPER reduction.
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
Silencing circUSP48 suppresses osteosarcoma progression by regulating the miR-335/ smad nuclear interacting protein 1 pathway.
Quercetin inhibits the amphiregulin/EGFR signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in obstructive nephropathy.
Pathological implication of CaMKII in NF-κB pathway and SASP during cardiomyocytes senescence.
Targeting 7-dehydrocholesterol reductase against EV-A71 replication by upregulating interferon response.
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Translational control of murine adiponectin expression by an upstream open reading frame element.
Eugenol attenuates ischemia-mediated oxidative stress in cardiomyocytes via acetylation of histone at H3K27.
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Extracellular magnetic labeling of biomimetic hydrogel-induced human mesenchymal stem cell spheroids with ferumoxytol for MRI tracking.
BRD4 inhibitor suppresses melanoma metastasis via the SPINK6/EGFR-EphA2 pathway.
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Transforming growth factor-β1 promotes early odontoblastic differentiation of dental pulp stem cells via activating AKT, Erk1/2 and p38 MAPK pathways.
Circ_0004491 stimulates guanine nucleotide-binding protein alpha subunit to inhibit the malignant progression of oral squamous cell carcinoma by sponging miR-2278.
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Pyruvate dehydrogenase kinase 4 promotes osteoblastic potential of BMP9 by boosting Wnt/β-catenin signaling in mesenchymal stem cells.
Diagnostic, prognostic, and immunological roles of CD177 in cervical cancer.
Parasympathetic-macrophages-ductal epithelial cells axis promotes female rat submandibular gland regeneration after excretory duct ligation/deligation.
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Co-Polymer Carrier with Dual Advantages of Cartilage-Penetrating and Targeting Improves Delivery and Efficacy of MicroRNA Treatment of Osteoarthritis.
Development and validation of a leukocyte-associated immunoglobulin-like receptor-1 prognostic signature for lower-grade gliomas.
Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury.
Amelioration of central neurodegeneration by docosahexaenoic acid in trigeminal neuralgia rats through the regulation of central neuroinflammation.
Huc-MSCs-derived exosomes attenuate neuropathic pain by inhibiting activation of the TLR2/MyD88/NF-κB signaling pathway in the spinal microglia by targeting Rsad2.
Halofuginone ameliorates systemic lupus erythematosus by targeting Blk in myeloid-derived suppressor cells.
Effective-compounds of Jinshui Huanxian formula ameliorates fibroblast activation in pulmonary fibrosis by inhibiting the activation of mTOR signaling.
Shikonin triggers GSDME-mediated pyroptosis in tumours by regulating autophagy via the ROS-MAPK14/p38α axis.
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Neuronal differentiation drives the antitumor activity of mitogen-activated protein kinase kinase (MEK) inhibition in glioblastoma.
Treatment with paraquat affects the expression of ferroptosis-related genes.
Immunopotentiation effects of apigenin on NK cell proliferation and killing pancreatic cancer cells.
1,25-Dihydroxyvitamin D3: A Positive Factor for the Osteogenic Differentiation of hPDLSCs and for the Tissue Regenerative Activity of Cell Sheets.
SUV39H1 Inhibits Angiogenesis in Limb Ischemia of Mice.
Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis.
Elevated Angiotensin-II Levels Contribute to the Pathogenesis of Open-Angle Glaucoma Via Inducing the Expression of Fibrosis-Related Genes in Trabecular Meshwork Cells Through a ROS/NOX4/SMAD3 Axis.
Hypermethylation-Mediated lncRNA MAGI2-AS3 Downregulation Facilitates Malignant Progression of Laryngeal Squamous Cell Carcinoma via Interacting With SPT6.
DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer.
Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1.
Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization.
PAK1 Is Involved in the Spindle Assembly during the First Meiotic Division in Porcine Oocytes.
A distal super-enhancer activates oncogenic ETS2 via recruiting MECOM in inflammatory bowel disease and colorectal cancer.
Impact of Hypermannosylation on the Structure and Functionality of the ER and the Golgi Complex.
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Co-delivery of ibrutinib and hydroxychloroquine by albumin nanoparticles for enhanced chemotherapy of glioma.
Human zygotic genome activation is initiated from paternal genome.
TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis.
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Development and validation of an inflammatory response-related prognostic model and immune infiltration analysis in glioblastoma.
Network and experimental pharmacology on mechanism of Si-Wu-tang improving ovarian function in a mouse model of premature ovarian failure induced by cyclophosphamide.
Fufang-zhenzhu-tiaozhi formula protects islet against injury and promotes β cell regeneration in diabetic mice.
Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis.
Nanoparticulate MgH(2) ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
Matrine combined with Osthole inhibited the PERK apoptosis of splenic lymphocytes in PCV2-infected mice model.
Protective effects of Lycium barbarum L. berry extracts against oxidative stress-induced damage of the retina of aging mouse and ARPE-19 cells.
Dietary leucine and fish oil cooperatively regulate skeletal myofiber type transformation via the CaMKII signaling pathway of pigs.
Goat FADS2 controlling fatty acid metabolism is directly regulated by SREBP1 in mammary epithelial cells.
Activation of autophagy inhibits the activation of NLRP3 inflammasome and alleviates sevoflurane-induced cognitive dysfunction in elderly rats.
Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction.
Anti-inflammatory and Chondroprotective Effects of Platelet-derived Growth Factor-BB on Osteoarthritis Rat Models.
Naringenin Ameliorates Hyperuricemia by Regulating Renal Uric Acid Excretion via the PI3K/AKT Signaling Pathway and Renal Inflammation through the NF-κB Signaling Pathway.
Master mitotic kinases regulate viral genome delivery during papillomavirus cell entry.
Microglial activation and over pruning involved in developmental epilepsy.
Inhibition of fibroblast activation protein ameliorates cartilage matrix degradation and osteoarthritis progression.
USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.
LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway.
Comparison of DNA targeting CRISPR editors in human cells.
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
Gardenoside ameliorates inflammation and inhibits ECM degradation in IL-1β-treated rat chondrocytes via suppressing NF-κB signaling pathways.
MiR-652-3p promotes malignancy and metastasis of cancer cells via inhibiting TNRC6A in hepatocellular carcinoma.
Genetic screening of MMP1 as a potential pathogenic gene in chronic obstructive pulmonary disease.
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
Cross-talk between autophagy and ferroptosis contributes to the liver injury induced by fluoride via the mtROS-dependent pathway.
Inhibition of the AKT1/mTOR pathway through SIRT6 over expression downregulated the expression of programmed death-ligand 1 and prolonged overall survival in lung adenocarcinoma.
ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury.
Cross-Talk between N6-Methyladenosine and Their Related RNAs Defined a Signature and Confirmed m6A Regulators for Diagnosis of Endometriosis.
Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway.
Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification.
CircZBTB46 Protects Acute Myeloid Leukemia Cells from Ferroptotic Cell Death by Upregulating SCD.
Acceleration of Oral Wound Healing under Diabetes Mellitus Conditions Using Bioadhesive Hydrogel.
Microglia-Derived Spp1 Promotes Pathological Retinal Neovascularization via Activating Endothelial Kit/Akt/mTOR Signaling.
LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer.
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Crosstalk between 5-methylcytosine and N(6)-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma.
Pseudogene TDGF1P3 regulates the proliferation and metastasis of colorectal cancer cells via the miR-338-3p-PKM2 axis.
Combined therapy of GABA and sitagliptin prevents high-fat diet impairment of beta-cell function.
IFI204 protects host defense against Staphylococcus aureus-induced pneumonia by promoting extracellular traps formation.
PRMT6 functionally associates with PRMT5 to promote colorectal cancer progression through epigenetically repressing the expression of CDKN2B and CCNG1.
Effects of chronic realgar exposure on liver lipidome in mice and identification sensitive lipid biomarker model for realgar-induced liver damage.
DNA methylation-mediated silencing of Neuronatin promotes hepatocellular carcinoma proliferation through the PI3K-Akt signaling pathway.
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Infiltrating circulating monocytes provide an important source of BMP4 at the early stage of spinal cord injury.
Adipose-derived stem cells with miR-150-5p inhibition laden in hydroxyapatite/tricalcium phosphate ceramic powders promote osteogenesis via regulating Notch3 and activating FAK/ERK and RhoA.
Suppression of lncRNA Snhg1 inhibits high glucose-induced inflammation and proliferation in mouse mesangial cells.
α2,6-Sialylation promotes hepatocellular carcinoma cells migration and invasion via enhancement of nSmase2-mediated exosomal miRNA sorting.
SNHG3 regulates NEIL3 via transcription factor E2F1 to mediate malignant proliferation of hepatocellular carcinoma.
Mitophagy-promoting miR-138-5p promoter demethylation inhibits pyroptosis in sepsis-associated acute lung injury.
GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis.
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
METTL21C mediates lysine trimethylation of IGF2BP1 to regulate chicken myoblast proliferation.
Expression of transforming growth factor-β1 and autophagy markers in the bladder of rats with neurogenic lower urinary tract injury.
Silencing CircEIF3I/miR-526b-5p Axis Epigenetically Targets HGF/c-Met Signal to Hinder the Malignant Growth, Metastasis and Angiogenesis of Hepatocellular Carcinoma.
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Incorporation of glycyrrhizic acid and polyene phosphatidylcholine in lipid nanoparticles ameliorates acute liver injury via delivering p65 siRNA.
Tetrahydroberberrubine retards heart aging in mice by promoting PHB2-mediated mitophagy.
Pharmacological suppression of NLRP3 inflammasome attenuated the development of autoimmune thyroiditis.
The long non-coding RNA PANDAR regulates cell proliferation and epithelial-to-mesenchymal transition in glioma.
OGG1 inhibition suppresses African swine fever virus replication.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
EphA4/EphrinB2 signaling mediates pericyte-induced transient glia limitans formation as a secondary protective barrier after subarachnoid hemorrhage in mice.
Protective roles of tRNA-derived small RNA tRF-Ile-AAT-019 in pathological progression of psoriasis.
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
SNORD88C guided 2'-O-methylation of 28S rRNA regulates SCD1 translation to inhibit autophagy and promote growth and metastasis in non-small cell lung cancer.
Effect of stretch frequency on osteogenesis of periodontium during periodontal ligament distraction.
IL-17A promotes endothelial cell senescence by up-regulating the expression of FTO through activating JNK signal pathway.
lncRNA SND1-IT1 delivered via intracerebral hemorrhage-derived exosomes affect the growth of human microglia by regulating the miR-124-3p/MTF1 axis.
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
Molybdenum and Cadmium Co-induce Pyroptosis via Inhibiting Nrf2-Mediated Antioxidant Defense Response in the Brain of Ducks.
BMP6 regulates AMH expression via SMAD1/5/8 in goat ovarian granulosa cells.
Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.
Exosomal miR-211-5p regulates glucose metabolism, pyroptosis, and immune microenvironment of melanoma through GNA15.
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Hyperlipidemia impacts osteogenesis via lipophagy.
Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics.
PLK1 protects intestinal barrier function in sepsis: A translational research.
Rutin ameliorates gout via reducing XOD activity, inhibiting ROS production and NLRP3 inflammasome activation in quail.
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
NOD2 inhibits the proliferation of esophageal adenocarcinoma cells through autophagy.
Tumor-derived endomucin promotes colorectal cancer proliferation and metastasis.
Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis.
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages.
Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy.
JAK2 inhibitor ameliorates the progression of experimental autoimmune myasthenia gravis and balances Th17/Treg cells via regulating the JAK2/STAT3-AKT/mTOR signaling pathway.
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Anoikis patterns exhibit distinct prognostic and immune landscapes in Osteosarcoma.
Indirubin protects chondrocytes and alleviates OA by inhibiting the MAPK and NF-κB pathways.
Taxifolin ameliorates cigarette smoke-induced chronic obstructive pulmonary disease via inhibiting inflammation and apoptosis.
Isothiocyanates attenuate immune checkpoint blockage therapy in gastric cancer via induction of PD-L1 expression.
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics.
Progranulin deficiency suppresses allergic asthma and enhances efferocytosis via PPAR-γ/MFG-E8 regulation in macrophages.
L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism.
Regulatory T Cells Overexpressing Peli1 Show Better Efficacy in Repairing Ovarian Endocrine Function in Autoimmune Premature Ovarian Insufficiency.
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis.
Non-Esterified Fatty Acid-Induced Apoptosis in Bovine Granulosa Cells via ROS-Activated PI3K/AKT/FoxO1 Pathway.
Genetic dissection of the impact of lncRNA AI662270 during the development of atherosclerosis.
Study of the inflammatory activating process in the early stage of Fusobacterium nucleatum infected PDLSCs.
Anemoside A3 Inhibits Macrophage M2-Like Polarization to Prevent Triple-Negative Breast Cancer Metastasis.
Administration of Huperzine A microspheres ameliorates myocardial ischemic injury via α7nAChR-dependent JAK2/STAT3 signaling pathway.
Cyclic diguanylate analogues: Facile synthesis, STING binding mode and anti-tumor immunity delivered by cytidinyl/cationic lipid.
ZNF385A and ZNF346 Serve as Prognostic Biomarkers Associated with an Inflamed Immunosuppressive Tumor Microenvironment in Hepatocellular Carcinoma.
Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
NRXN1 depletion in the medial prefrontal cortex induces anxiety-like behaviors and abnormal social phenotypes along with impaired neurite outgrowth in rat.
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
Thermoresponsive Ozone-Enriched Spray Gel for Postsurgical Treatment of Hepatocellular Carcinoma.
Elevated NDC1 expression predicts poor prognosis and correlates with immunity in hepatocellular carcinoma.
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
KIF2C Facilitates Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma.
Dual regulation of Akt and glutathione caused by isoalantolactone effectively triggers human ovarian cancer cell apoptosis.
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
The Investigation of the Molecular Mechanism of Morinda officinalis How in the Treatment of Heart Failure.
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10.
Comprehensive Analysis of Prognosis and Immune Landscapes Based on Lipid-Metabolism- and Ferroptosis-Associated Signature in Uterine Corpus Endometrial Carcinoma.
The pluripotency factor Tex10 finetunes Wnt signaling for PGC and male germline development.
Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stress.
Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation.
TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1.
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor.
Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia.
LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei.
[A convenient and time-saving method for primary culture of mature white adipocytes from mice].
[Fibroblasts overpressing WNT2b cause impairment of intestinal mucosal barrier].
Tra2β Enhances Cell Proliferation by Inducing the Expression of Transcription Factor SP1 in Cervical Cancer.
YTHDF1 Attenuates TBI-Induced Brain-Gut Axis Dysfunction in Mice.
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis.
ERCC6L facilitates the progression of laryngeal squamous cell carcinoma by the binding of FOXM1 and KIF4A.
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Alpha-kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway.
Malvidin-3-O-Glucoside Ameliorates Cadmium-Mediated Cell Dysfunction in the Estradiol Generation of Human Granulosa Cells.
Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection.
LincRNA ZNF529-AS1 inhibits hepatocellular carcinoma via FBXO31 and predicts the prognosis of hepatocellular carcinoma patients.
MiR-21 Is Induced by Hypoxia and Down-Regulates RHOB in Prostate Cancer.
Oxymatrine attenuated isoproterenol-induced heart failure via the TLR4/NF-κB and MAPK pathways in vivo and in vitro.
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis.
Metformin regulates autophagy via LGMN to inhibit choriocarcinoma.
RBM10 recruits METTL3 to induce N6-methyladenosine-MALAT1-dependent modification, inhibiting the invasion and migration of NSCLC.
Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.
Hydrogen Sulfide Inhibited Sympathetic Activation in D-Galactose-Induced Aging Rats by Upregulating Klotho and Inhibiting Inflammation in the Paraventricular Nucleus.
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
m6A contributes to a pro-survival state in GC-2 cells by facilitating DNA damage repair: Novel perspectives on the mechanism underlying DEHP genotoxicity in male germ cells.
To explore the regulatory role of Wnt/P53/Caspase3 signal in mouse ovarian development based on LFQ proteomics.
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy.
HDAC Inhibitors Alleviate Uric Acid-Induced Vascular Endothelial Cell Injury by Way of the HDAC6/FGF21/PI3K/AKT Pathway.
ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries.
Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis.
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Core-shell SERS nanotags-based western blot.
Theilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor, Melanoma Differentiation-Associated Gene 5, and Impairs Double-Stranded RNA-Mediated IFN Response.
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Heat stress suppresses MnSOD expression via p53-Sp1 interaction and induces oxidative stress damage in endothelial cells: Protective effects of MitoQ10 and Pifithrin-α.
Inhibited Expression of NLRP12 Promotes the Development of Triple-Negative Breast Cancer by Activating the NF-κB Pathway.
BCLAF1-induced HIF-1α accumulation under normoxia enhances PD-L1 treatment resistances via BCLAF1-CUL3 complex.
Long noncoding RNA RMRP ameliorates doxorubicin-induced apoptosis by interacting with PFN1 in a P53-Dependent manner.
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells.
Survivin regulates intracellular stiffness and extracellular matrix production in vascular smooth muscle cells.
Vitamin D Receptor Activation Attenuates Olanzapine-Induced Dyslipidemia in Mice Through Alleviating Hepatic Endoplasmic Reticulum Stress.
Simvastatin inhibits proliferation and promotes apoptosis of oral squamous cell carcinoma through KLF2 signal.
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport.
JianPi-QingHua formula attenuates nonalcoholic fatty liver disease by regulating the AMPK/SIRT1/NF-κB pathway in high-fat-diet-fed C57BL/6 mice.
Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor.
Prokinetic effects of Citrus reticulata and Citrus aurantium extract with/without Bupleurum chinense using multistress-induced delayed gastric emptying models.
Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway.
Luteolin alleviated neutrophilic asthma by inhibiting IL-36γ secretion-mediated MAPK pathways.
Novel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/β-catenin signalling pathway.
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
miR-141-3p alleviates ulcerative colitis by targeting SUGT1 to inhibit colonic epithelial cell pyroptosis.
Binding of berberine to PEBP1 synergizes with sorafenib to induce the ferroptosis of hepatic stellate cells.
Astragaloside IV ameliorate acute alcohol-induced liver injury in mice via modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway.
Dexmedetomidine enables copper homeostasis in cerebral ischemia/reperfusion via ferredoxin 1.
Study on tumour cell-derived hybrid exosomes as dasatinib nanocarriers for pancreatic cancer therapy.
An impaired ubiquitin-proteasome system increases APOBEC3A abundance.
Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC.
Chitosan oligosaccharide attenuates acute kidney injury and renal interstitial fibrosis induced by ischemia-reperfusion.
Apelin-13 alleviates contrast-induced acute kidney injury by inhibiting endoplasmic reticulum stress.
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells.
LOXL3 Inhibits Autophagy of Chondrocytes by Activating Rheb in Osteoarthritis.
PPARβ/δ activation protects against hepatic ischaemia-reperfusion injury.
Aggf1 Specifies Hemangioblasts at the Top of Regulatory Hierarchy via Npas4l and mTOR-S6K-Emp2-ERK Signaling.
Peripheral BDNF Regulates Somatosensory-Sympathetic Coupling in Brachial Plexus Avulsion-Induced Neuropathic Pain.
Talin1 regulates glucose metabolism and endometrial receptivity via GLUT-4 in patients with polycystic ovary syndrome and insulin resistance.
MiR-5195-3p functions as a tumor suppressor by targeting RHBDD1 in ovarian cancer.
Activation of moderate autophagy promotes survival of fat graft.
Periostin promotes extensive neovascularization in placenta accreta spectrum disorders via Notch signaling.
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
HIF-1α promotes astrocytic production of macrophage migration inhibitory factor following spinal cord injury.
Cystathionine γ-lyase S-sulfhydrates SIRT1 to attenuate myocardial death in isoprenaline-induced heart failure.
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
hsa-miR-1301-3p Promotes the Proliferation and Migration of Nonsmall Cell Lung Cancer Cells and Reduces Radiosensitivity via Targeting Homeodomain-Only Protein Homeobox.
Exploring the mechanism of resistance to vincristine in breast cancer cells using transcriptome sequencing technology.
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
Porous gelatin microspheres implanted with adipose mesenchymal stromal cells promote angiogenesis via protein kinase B/endothelial nitric oxide synthase signaling pathway in bladder reconstruction.
Zinc Overload Induces Damage to H9c2 Cardiomyocyte Through Mitochondrial Dysfunction and ROS-Mediated Mitophagy.
BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2.
Ginsenoside Rb2 improves heart failure by down-regulating miR-216a-5p to promote autophagy and inhibit apoptosis and oxidative stress.
Metformin attenuates inflammation and boosts autophagy in the liver and intestine of chronologically aged rats.
ZnO nanoparticles impair autophagic flux and cell viability through the TRIM16-NRF2-p62 pathway in inflammatory keratinocytes.
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status.
Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals.
Synergistic inhibition of NUDT21 by secretory S100A11 and exosomal miR-487a-5p promotes melanoma oligo- to poly-metastatic progression.
Protocatechuic aldehyde increases pericyte coverage and mitigates pericyte damage to enhance the atherosclerotic plaque stability.
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression.
Antinociceptive and neuroprotective effect of echinacoside on peripheral neuropathic pain in mice through inhibiting P2X7R/FKN/CX3CR1 pathway.
Increasing expression of STING by ERα antagonizes LCN2 downregulation during chronic endometritis.
Therapeutic potential and protective role of GRK6 overexpression in pulmonary arterial hypertension.
MicroRNA-367-3p directly targets RAB23 and inhibits proliferation, migration and invasion of bladder cancer cells and increases cisplatin sensitivity.
LRRC8A promotes Glaesserella parasuis cytolethal distending toxin-induced p53-dependent apoptosis in NPTr cells.
Retracted Article: Exosomes from bone marrow mesenchymal stem cells promoted osteogenic differentiation by delivering miR-196a that targeted Dickkopf-1 to activate Wnt/β-catenin pathway.
USP7 promotes non-small-cell lung cancer cell glycolysis and survival by stabilizing and activating c-Abl.
Artesunate alleviates diabetic retinopathy by activating autophagy via the regulation of AMPK/SIRT1 pathway.
In vitro and in vivo killing effects of methionine enkephalin on osteosarcoma.
Diabetic and nondiabetic BMSC-derived exosomes affect bone regeneration via regulating miR-17-5p/SMAD7 axis.
Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis.
Sodium alginate combined with oxymatrine ameliorates CCl(4)-induced chemical hepatic fibrosis in mice.
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells.
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
PGC1α deficiency reverses cholestasis-induced liver injury via attenuating hepatic inflammation and promoting bile duct remodeling.
ABTB1 facilitates the replication of influenza A virus by counteracting TRIM4-mediated degradation of viral NP protein.
CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis.
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc.
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
lncRNA GPRC5D-AS1 as a ceRNA inhibits skeletal muscle aging by regulating miR-520d-5p.
Synergistic effect of cryptotanshinone and temozolomide treatment against human glioblastoma cells.
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression.
Development of an iron overload HepG2 cell model using ferrous ammonium citrate.
CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity.
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Pien Tze Huang alleviates Concanavalin A-induced autoimmune hepatitis by regulating intestinal microbiota and memory regulatory T cells.
A chromosome-level genome assembly for the Silkie chicken resolves complete sequences for key chicken metabolic, reproductive, and immunity genes.
CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation.
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
Shizhifang ameliorates pyroptosis of renal tubular epithelial cells in hyperuricemia through inhibiting NLRP3 inflammasome.
Anti-inflammatory effect and component analysis of Chaihu Qingwen granules.
The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptor.
A New HEK293 Cell with CR2 Region of E1A Gene Deletion Prevents the Emergence of Replication-Competent Adenovirus.
Alternative splicing of histone demethylase Kdm6bb mediates temperature-induced sex reversal in the Nile tilapia.
Chemokine- and chemokine receptor-based signature predicts immunotherapy response in female colorectal adenocarcinoma patients.
Choline induced cardiac dysfunction by inhibiting the production of endogenous hydrogen sulfide in spontaneously hypertensive rats.
Liver proteomics analysis reveals the differentiation of lipid mechanism and antioxidant enzyme activity during chicken embryonic development.
Selection of goat β-casein derived ACE-inhibitory peptide SQPK and insights into its effect and regulatory mechanism on the function of endothelial cells.
PRRSV alters m(6)A methylation and alternative splicing to regulate immune, extracellular matrix-associated function.
NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA.
MiR-128-1-5p inhibits cell proliferation and induces cell apoptosis via targeting PRKCQ in colorectal cancer.
CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma.
Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia.
NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells.
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy.
Luteolin Alleviates Oxidative Stress in Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke via Modulation of the TRPV1 and CYP2A13/NRF2 Signaling Pathways.
FHL2 Inhibits SARS-CoV-2 Replication by Enhancing IFN-β Expression through Regulating IRF-3.
Exosomal ITGB6 from dormant lung adenocarcinoma cells activates cancer-associated fibroblasts by KLF10 positive feedback loop and the TGF-β pathway.
Mesenchymal stem cell exosomes inhibit nucleus pulposus cell apoptosis via the miR-125b-5p/TRAF6/NF-κB pathway axis.
Endometrial stromal cell autophagy-dependent ferroptosis caused by iron overload in ovarian endometriosis is inhibited by the ATF4-xCT pathway.
FT895 Impairs Mitochondrial Function in Malignant Peripheral Nerve Sheath Tumor Cells.
Autophagy-related 7 proteindependent autophagy mediates resveratrol-caused upregulation of mitochondrial biogenesis and steroidogenesis in aged Leydig cell.
Linoleic acid: a natural feed compound against porcine epidemic diarrhea disease.
Circular RNA MTCL1 targets SMAD3 by sponging miR-145-5p for regulation of cell proliferation and migration in Hirschsprung's disease.
Experimental validation and pan-cancer analysis identified COL10A1 as a novel oncogene and potential therapeutic target in prostate cancer.
Novel Antioxidant Peptides Derived from Feather Keratin Alleviate H(2)O(2)-Induced Oxidative Damage in HepG2 Cells via Keap1/Nrf2 Pathway.
[m(6)A methylase WTAP participates in renal ischemia-reperfusion injury by regulating FOXO1 expression].
Integrated Amino Acids and Transcriptome Analysis Reveals Arginine Transporter SLC7A2 Is a Novel Regulator of Myogenic Differentiation.
ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway.
Elevated FBXL6 activates both wild-type KRAS and mutant KRAS(G12D) and drives HCC tumorigenesis via the ERK/mTOR/PRELID2/ROS axis in mice.
Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.
Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation.
Melatonin alleviates pyroptosis by regulating the SIRT3/FOXO3α/ROS axis and interacting with apoptosis in Atherosclerosis progression.
Predictive Roles of ADAM17 in Patient Survival and Immune Cell Infiltration in Hepatocellular Carcinoma.
The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication.
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease.
GETV nsP2 plays a critical role in the interferon antagonism and viral pathogenesis.
LLGL2 Inhibits Ovarian Cancer Metastasis by Regulating Cytoskeleton Remodeling via ACTN1.
DDX5 Functions as a Tumor Suppressor in Tongue Cancer.
α5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape.
Quercitrin attenuates the progression of osteoarthritis via inhibiting NF-κB signaling pathways and enhance glucose transport capacity.
Protocol for preparing Thiopropyl Sepharose resin used for capturing S-nitrosylated proteins.
Profibrotic role of transcription factor SP1 in cross-talk between fibroblasts and M2 macrophages.
Perfluorooctanoic acid disrupts thyroid-specific genes expression and regulation via the TSH-TSHR signaling pathway in thyroid cells.
Transient receptor potential-related risk model predicts prognosis of hepatocellular carcinoma patients.
Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice.
Bioinformatics-based identification and validation of hub genes associated with aging in patients with coronary artery disease.
Different glycosylation profiles of cystatin F alter the cytotoxic potential of natural killer cells.
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
Alpha-defensins inhibit ERK/STAT3 signaling during monocyte-macrophage differentiation and impede macrophage function.
A positive feedback loop between ZEB2 and ACSL4 regulates lipid metabolism to promote breast cancer metastasis.
MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression.
Neuropilin 1 promotes unilateral ureteral obstruction-induced renal fibrosis via RACK1 in renal tubular epithelial cells.
The linear ANRIL transcript P14AS regulates the NF-κB signaling to promote colon cancer progression.
Chlorin e6 (Ce6)-loaded plaque-specific liposome with enhanced photodynamic therapy effect for atherosclerosis treatment.
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
Mitophagy-dependent cardioprotection of resistance training on heart failure.
CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.
Markerless bacterial artificial chromosome manipulation method by red proteins of phage λ mediated homologous recombination utilizing fluorescent proteins for both positive and counter selection.
Heterophyllin B ameliorates gastric cancer tumor growth through activating ER stress.
Soluble dipeptidyl peptidase-4 induces epithelial-mesenchymal transition through tumor growth factor-β receptor.
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning.
Exosomal PPARγ derived from macrophages suppresses LPS-induced peritonitis by negative regulation of CD14/TLR4 axis.
Cyclic helix B peptide alleviates proinflammatory cell death and improves functional recovery after traumatic spinal cord injury.
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
Osmotic pressure induces translocation of aquaporin-8 by P38 and JNK MAPK signaling pathways in patients with functional constipation.
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
hsa_circ_0000417 downregulation suppresses androgen receptor expression and apoptotic signals in human foreskin fibroblasts via sponging miR-6756-5p.
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
JMJD3 ablation in myeloid cells confers renoprotection in mice with DOCA/salt-induced hypertension.
Brain-targeted lycopene-loaded microemulsion modulates neuroinflammation, oxidative stress, apoptosis and synaptic plasticity in β-amyloid-induced Alzheimer's disease mice.
AMP-activated protein kinase-farnesoid X receptor pathway contributes to oleanolic acid-induced liver injury.
An early-onset SLE patient with a novel paternal inherited BACH2 mutation.
Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS-mediated mitochondrial pathway.
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
Mulberry leaf water extract alleviates type 2 diabetes in mice via modulating gut microbiota-host co-metabolism of branched-chain amino acid.
Withdrawal: CircKIAA1429 accelerates hepatocellular carcinoma advancement by miR-199b-5p/OTX1 pathway, by Bin Lu, Min Cheng, Tao Wang.
Journal of viral hepatitis 2023 Aug;30(8):713
A MAPK signaling cascade regulates the fusaric acid-induced cell death in Arabidopsis.
Complement factor H inhibits endothelial cell migration through suppression of STAT3 signaling.
SUV39H1 is a prognosis and immune microenvironment-related biomarker in diffuse large B-cell lymphoma.
SOX9/NFIA promotes human ovarian cancer metastasis through the Wnt/β-catenin signaling pathway.
Complement C3a receptor antagonist alleviates tau pathology and ameliorates cognitive deficits in P301S mice.
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations.
EIF4A3-Induced Exosomal circLRRC8A Alleviates Granulosa Cells Senescence Via the miR-125a-3p/NFE2L1 axis.
Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice.
Piezo1 suppression reduces demyelination after intracerebral hemorrhage.
Inhibition of CDCP1 by 8-isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment.
p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis.
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
Emerging glyco-risk prediction model to forecast response to immune checkpoint inhibitors in colorectal cancer.
HPV18 E6 inhibits α-ketoglutarate-induced pyroptosis of esophageal squamous cell carcinoma cells via the P53/MDH1/ROS/GSDMC pathway.
Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin.
The ALOX5 inhibitor Zileuton regulates tumor-associated macrophage M2 polarization by JAK/STAT and inhibits pancreatic cancer invasion and metastasis.
GKLF, a transcriptional activator of Txnip, drives microglia activation in kainic acid-induced murine models of epileptic seizures.
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
Ketogenic diet alleviates renal interstitial fibrosis in UUO mice by regulating macrophage proliferation.
Low androgen levels induce ferroptosis of rat penile cavernous endothelial cells.
DNA methylation of RUNX3 promotes the progression of gallbladder cancer through repressing SLC7A11-mediated ferroptosis.
Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway.
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration.
Loss of N-acetylglucosaminyl transferase V is involved in the impaired osteogenic differentiation of bone marrow mesenchymal stem cells.
Expression and localization of α(2A)-adrenergic receptor in the rat post-natal developing cochlea.
DKK1-targeting cholesterol-modified siRNA implication in hair growth regulation.
Inhibit ALDH3A2 reduce ovarian cancer cells survival via elevating ferroptosis sensitivity.
Inhibition of human adenovirus replication by TRIM35-mediated degradation of E1A.
Salidroside Supplementation Affects In Vitro Maturation and Preimplantation Embryonic Development by Promoting Meiotic Resumption.
Exploring the Therapeutic Potential of Ethyl 3-Hydroxybutyrate in Alleviating Skeletal Muscle Wasting in Cancer Cachexia.
The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis.
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal.
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner.
METTL3-mediated m6A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial-mesenchymal transition.
Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia.
Subcellular localization shapes the fate of RNA polymerase III.
Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome.
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
MiR-297 inhibits tumour progression of liver cancer by targeting PTBP3.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp.
METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway.
Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis.
Circ_0000235 targets MCT4 to promote glycolysis and progression of bladder cancer by sponging miR-330-5p.
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
[Characteristics and microRNA expression profile of exosomes derived from odontogenic dental pulp stem cells].
Sinomenine alleviates lipopolysaccharide-induced acute lung injury via a PPARβ/δ-dependent mechanism.
The mitochondrial-derived peptide MOTS-c suppresses ferroptosis and alleviates acute lung injury induced by myocardial ischemia reperfusion via PPARγ signaling pathway.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
linc01515 regulates PM(2.5)-induced oxidative stress via targeting NRF2 in airway epithelial cells.
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Mitochondrial protein MPV17 promotes β-cell apoptosis in diabetogenesis.
Anthraquinone metabolites isolated from the rhizosphere soil Streptomyces of Panax notoginseng (Burk.) F. H. Chen target MMP2 to inhibit cancer cell migration.
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein.
Molecular mechanism of kidney damage caused by abamectin in carp: Oxidative stress, inflammation, mitochondrial damage, and apoptosis.
TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling.
Ruxolitinib Alleviates Inflammation, Apoptosis, and Intestinal Barrier Leakage in Ulcerative Colitis via STAT3.
Overlaid Transcriptional and Proteome Analyses Identify Mitotic Kinesins as Important Targets of Arylsulfonamide-Mediated RBM39 Degradation.
MTHFD1 is critical for the negative regulation of retinoic acid receptor signalling in anencephaly.
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Houpo paiqi mixture promotes intestinal motility in constipated rats by modulating gut microbiota and activating 5-HT-cAMP-PKA signal pathway.
rhMYDGF Alleviates I/R-induced Kidney Injury by Inhibiting Inflammation and Apoptosis via the Akt Pathway.
An active fraction from Spatholobus suberectus dunn inhibits the inflammatory response by regulating microglia activation, switching microglia polarization from M1 to M2 and suppressing the TLR4/MyD88/NF-κB pathway in LPS-stimulated BV2 cells.
Corticostriatal Projections Relying on GABA Levels Mediate Exercise-Induced Functional Recovery in Cerebral Ischemic Mice.
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
Molecular docking and in vitro experiments verified that kaempferol induced apoptosis and inhibited human HepG2 cell proliferation by targeting BAX, CDK1, and JUN.
Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer.
Inhibiting PAC1 receptor internalization and endosomal ERK pathway activation may ameliorate hyperalgesia in a chronic migraine rat model.
C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis.
L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis.
Inhibition of autophagic flux by the curcumin analog EF-24 and its antiproliferative effect on MCF-7 cancer cells.
CEBPB upregulates P4HA2 to promote the malignant biological behavior in IDH1 wildtype glioma.
LINC01232 promotes lung squamous cell carcinoma progression through modulating miR-181a-5p/SMAD2 axis.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos.
Integrative Analysis of ceRNA Networks in human periodontal ligament stem cells under hypoxia.
The enzymatic hydrolysate of fucoidan from Sargassum hemiphyllum triggers immunity in plants.
Transcriptomic analysis of the effects of the HPV18 E6E7 gene on the cell death mode in esophageal squamous cell carcinoma.
CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.
CMPK2 restricts Zika virus replication by inhibiting viral translation.
Epiberberine regulates lipid synthesis through SHP (NR0B2) to improve non-alcoholic steatohepatitis.
Poly-L-ornithine blocks the inhibitory effects of fibronectin on oligodendrocyte differentiation and promotes myelin repair.
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
lncR-GAS5 upregulates the splicing factor SRSF10 to impair endothelial autophagy, leading to atherogenesis.
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma.
Dysregulation of alternative splicing contributes to multiple myeloma pathogenesis.
Recombinant human p53 adenovirus injection combined with Bortezomib inhibits proliferation and promotes apoptosis in multiple myeloma.
TPX2 promotes ovarian tumorigenesis by interacting with Lamin A/C and affecting its stability.
IGFL2-AS1-induced suppression of HIF-1α degradation promotes cell proliferation and invasion in colorectal cancer by upregulating CA9.
Lithium-Containing Biomaterials Stimulate Cartilage Repair through Bone Marrow Stromal Cells-Derived Exosomal miR-455-3p and Histone H3 Acetylation.
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats.
The cGAS-STING pathway promotes endometriosis by up-regulating autophagy.
Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma.
Iron-frataxin involved in the protective effect of quercetin against alcohol-induced liver mitochondrial dysfunction.
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
PRPF19 facilitates colorectal cancer liver metastasis through activation of the Src-YAP1 pathway via K63-linked ubiquitination of MYL9.
Acetylcholine promotes chronic stress-induced lung adenocarcinoma progression via α5-nAChR/FHIT pathway.
Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy.
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Nobiletin Improves D-Galactose-Induced Aging Mice Skeletal Muscle Atrophy by Regulating Protein Homeostasis.
Active ingredients screening and pharmacological mechanism research of curcumae rhizoma-sparganii rhizoma herb pair ameliorates liver fibrosis based on network pharmacology.
Stearoyl-CoA Desaturases1 Accelerates Non-Small Cell Lung Cancer Metastasis by Promoting Aromatase Expression to Improve Estrogen Synthesis.
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
ANP32B promotes lung cancer progression by regulating VDAC1.
TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition.
RUNX1 Upregulation Causes Mitochondrial Dysfunction via Regulating the PI3K-Akt Pathway in iPSC from Patients with Down Syndrome.
NMR-Based Metabolic Profiling of the Effects of α-Ketoglutarate Supplementation on Energy-Deficient C2C12 Myotubes.
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling.
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Characterization of molecular subtypes based on chromatin regulators and identification of the role of NPAS2 in lung adenocarcinoma.
Pathophysiology of reinfection by exogenous HSV-1 is driven by heparanase dysfunction.
Investigation of the function of the novel tumor marker BEND5 in lung adenocarcinoma based on data mining and in vitro analysis.
Establishment of a Rat Model of Liver Venous Deprivation: Simultaneous Portal and Hepatic Vein Ligation.
RNF123 Mediates Ubiquitination and Degradation of SOCS1 To Regulate Type I Interferon Production during Duck Tembusu Virus Infection.
Systemic Analyses of Cuproptosis-Related lncRNAs in Pancreatic Adenocarcinoma, with a Focus on the Molecular Mechanism of LINC00853.
RIPK1-Induced A1 Reactive Astrocytes in Brain in MPTP-Treated Murine Model of Parkinson's Disease.
Development and validation of novel prognostic models for zinc finger proteins-related genes in soft tissue sarcoma.
Isthmin-1 (Ism1) modulates renal branching morphogenesis and mesenchyme condensation during early kidney development.
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA.
Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).
Human Embryonic Stem-Cell-Derived Exosomes Repress NLRP3 Inflammasome to Alleviate Pyroptosis in Nucleus Pulposus Cells by Transmitting miR-302c.
Nuclear bodies protect phase separated proteins from degradation in stressed proteome.
Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway.
Ursolic Acid Alleviates Cancer Cachexia and Prevents Muscle Wasting via Activating SIRT1.
Succinylation of CTBP1 mediated by KAT2A suppresses its inhibitory activity on the transcription of CDH1 to promote the progression of prostate cancer.
Pre-Protection and Mechanism of Crude Extracts from Dioscorea alata L. on H(2)O(2)-Induced IPEC-J2 Cells Oxidative Damage.
Antioxidant, Immunostimulatory, and Anticancer Properties of Hydrolyzed Wheat Bran Mediated through Macrophages Stimulation.
Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2.
Genetic deletion of phosphodiesterase 4D in the liver improves kidney damage in high-fat fed mice: liver-kidney crosstalk.
PIMT is a novel and potent suppressor of endothelial activation.
STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy.
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells.
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
LDL Affects the Immunomodulatory Response of Endothelial Cells by Modulation of the Promyelocytic Leukemia Protein (PML) Expression via PKC.
Effects of ketamine-induced H3K9 hypoacetylation during pregnancy on cardiogenesis of mouse offspring.
AKT Blocks SIK1-Mediated Repression of STAT3 to Promote Breast Tumorigenesis.
Protective Effects of Selenium Nanoparticles against Bisphenol A-Induced Toxicity in Porcine Intestinal Epithelial Cells.
microRNA-660 Enhances Cisplatin Sensitivity via Decreasing SATB2 Expression in Lung Adenocarcinoma.
Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation.
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Salvianolic Acid B Reduces the Inflammation of Fat Grafts by Inhibiting the NF-Kb Signalling Pathway in Macrophages.
The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter.
Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy.
PM(2.5) induce myocardial injury in hyperlipidemic mice through ROS-pyroptosis signaling pathway.
Prognostic marker C3AR1 is associated with ovarian cancer cell proliferation and immunosuppression in the tumor microenvironment.
Novel Experimental Mouse Model to Study Malaria-Associated Acute Kidney Injury.
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
Altered mannose metabolism in chronic stress and depression is rapidly reversed by vitamin B12.
Emodin from Aloe inhibits Swine acute diarrhea syndrome coronavirus in cell culture.
Ablation of cardiomyocyte-derived BDNF during development causes myocardial degeneration and heart failure in the adult mouse heart.
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway.
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
CircRNA-mediated regulation of brown adipose tissue adipogenesis.
Gypenosides ameliorate high-fat diet-induced non-alcoholic steatohepatitis via farnesoid X receptor activation.
Obesity by High-Fat Diet Increases Pain Sensitivity by Reprogramming Branched-Chain Amino Acid Catabolism in Dorsal Root Ganglia.
Comparison of the Effects of Inorganic or Amino Acid-Chelated Zinc on Mouse Myoblast Growth in vitro and Growth Performance and Carcass Traits in Growing-Finishing Pigs.
Cardiac ISL1-Interacting Protein, a Cardioprotective Factor, Inhibits the Transition From Cardiac Hypertrophy to Heart Failure.
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
Fructose Induces Insulin Resistance of Gestational Diabetes Mellitus in Mice via the NLRP3 Inflammasome Pathway.
Renal Denervation Attenuates Adverse Remodeling and Intramyocardial Inflammation in Acute Myocardial Infarction With Ischemia-Reperfusion Injury.
Antibiotic Therapy and Vaginal Microbiota Transplantation Reduce Endometriosis Disease Progression in Female Mice via NF-κB Signaling Pathway.
6-Shogaol Inhibits Oxidative Stress-Induced Rat Vascular Smooth Muscle Cell Apoptosis by Regulating OXR1-p53 Axis.
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
LncRNA FAM13A-AS1 Promotes Renal Carcinoma Tumorigenesis Through Sponging miR-141-3p to Upregulate NEK6 Expression.
Apigenin remodels the gut microbiota to ameliorate ulcerative colitis.
Maternal nucleotide supplementation improves the intestinal morphology and immune function in lipopolysaccharide-challenged newborn piglets.
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis.
Experimental Periodontitis Deteriorates Cognitive Function and Impairs Insulin Signaling in a Streptozotocin-Induced Alzheimer's Disease Rat Model.
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
Micro ribonucleic acid-448 regulates zinc finger e-box binding homeobox 1 to inhibit the growth of breast cancer cells and increase their sensitivity to chemotherapy.
MicroRNA-214-3p Ameliorates LPS-Induced Cardiomyocyte Injury by Inhibiting Cathepsin B.
The involvement of hormone-sensitive lipase in all-trans retinoic acid induced cleft palate.
Effects of miR-211-3p/RHBDD1 axis on cell proliferation, cell cycle progression, and epithelial-mesenchymal transition in glioma.
EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells.
Pterostilbene, a Resveratrol Derivative, Improves Ectopic Lipid Deposition in the Kidneys of Mice Induced by a High-Fat Diet.
MicroRNA-155-5p Targets NR3C2 to Promote Malignant Progression of Clear Cell Renal Cell Carcinoma.
Evacetrapib Elicits Antitumor Effects on Colorectal Cancer by Inhibiting the Wnt/β-Catenin Signaling Pathway and Activating the JNK Signaling Pathway.
Hyperthermia inhibits growth of nasopharyngeal carcinoma through degradation of c-Myc.
Tanshinone IIA ameliorates myocardial ischemia/reperfusion injury in rats by regulation of NLRP3 inflammasome activation and Th17 cells differentiation.
MiR-96-5p induced NDRG1 deficiency promotes prostate cancer migration and invasion through regulating the NF-κB signaling pathway.
Gallbladder Cancer Cell-Derived Exosome-Mediated Transfer of Leptin Promotes Cell Invasion and Migration by Modulating STAT3-Mediated M2 Macrophage Polarization.
Irisin Ameliorates Intervertebral Disc Degeneration by Activating LATS/YAP/CTGF Signaling.
The DeltaN p63 Promotes EMT and Metastasis in Bladder Cancer by the PTEN/AKT Signalling Pathway.
Transcriptional Patterns of Lower-Grade Glioma Patients with Distinct Ferroptosis Levels, Immunotherapy Response, and Temozolomide Sensitivity.
Downregulation of S100A9 Reverses Cisplatin-Resistance and Inhibits Proliferation and Migration in Hypopharyngeal Carcinoma.
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress.
Effect and Mechanism of lncRNA CERS6-AS1 on the Biological Behavior of Prostate Cancer Cell.
Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis.
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
FKN/NR Signaling Pathway Regulates Hippocampal Inflammatory Responses: the Survival of Hippocampal Neurons in Diabetic Rats with Chronic Unpredictable Mild Stress.
circ-Katnal1 Enhances Inflammatory Pyroptosis in Sepsis-Induced Liver Injury through the miR-31-5p/GSDMD Axis.
The E3 Ubiquitin Ligase TRIM11 Facilitates Gastric Cancer Progression by Activating the Wnt/β-Catenin Pathway via Destabilizing Axin1 Protein.
Long Intergenic Noncoding RNA 00641 Promotes Growth and Invasion of Colorectal Cancer through Regulating miR-450b-5p/GOLPH3 Axis.
In Vitro Immunomodulatory Effects of Inonotus obliquus Extracts on Resting M0 Macrophages and LPS-Induced M1 Macrophages.
Hypoxia Acclimation Protects against Heart Failure Postacute Myocardial Infarction via Fundc1-Mediated Mitophagy.
Apigenin Induced Apoptosis by Downregulating Sulfiredoxin Expression in Cutaneous Squamous Cell Carcinoma.
Effect of Lycium barbarum Polysaccharide on Decreasing Serum Amyloid A3 Expression through Inhibiting NF-κB Activation in a Mouse Model of Diabetic Nephropathy.
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
UHRF1 Induces Metastasis in Thyroid Cancer.
Protective Effects of Herba Houttuyniae Aqueous Extract against OVA-Induced Airway Hyperresponsiveness and Inflammation in Asthmatic Mice.
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
YTHDC1 Promotes Stemness Maintenance and Malignant Progression in Head and Neck Squamous Cell Carcinoma.
Fucoxanthin Attenuates Oxidative Damage by Activating the Sirt1/Nrf2/HO-1 Signaling Pathway to Protect the Kidney from Ischemia-Reperfusion Injury.
Exploring the Potential Mechanism of Qi-Shen-Di-Huang Drug Formulary for Myasthenia Gravis (MG) based on UHPLC-QE-MS Network Pharmacology and Molecular Docking Techniques.
Inhibition of Angiogenesis by MiR-524-5p through Suppression of AKT and ERK Activation by Targeting CXCR7 in Colon Cancer Cells.
Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21.
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
MicroRNA-323a-3p Negatively Regulates NEK6 in Colon Adenocarcinoma Cells.
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo.
Role of GLI1 in Hypoxia-Driven Endometrial Stromal Cell Migration and Invasion in Endometriosis.
Effects of Sodium Chlorophyllin Copper on APO-1 Expression in Bone Marrow Mesenchymal Stem Cells of Rats with Aplastic Anaemia.
Comprehensive Pan-Cancer Analysis of IRAK Family Genes Identifies IRAK1 as a Novel Oncogene in Low-Grade Glioma.
Glaucocalyxin B Attenuates Ovarian Cancer Cell Growth and Cisplatin Resistance In Vitro via Activating Oxidative Stress.
Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain.
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Metformin Exhibits an Attractive Antineoplastic Effect on Human Endometrial Cancer by Regulating the Hippo Signaling Pathway.
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
miR-212 Promotes Cardiomyocyte Hypertrophy through Regulating Transcription Factor 7 Like 2.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Long Noncoding RNA Hotair Promotes the Progression and Immune Escape in Laryngeal Squamous Cell Carcinoma through MicroRNA-30a/GRP78/PD-L1 Axis.
Network Pharmacology and Experimental Validation to Reveal Effects and Mechanisms of Icariin Combined with Nobiletin against Chronic Obstructive Pulmonary Diseases.
MiRNA-196-5p Promotes Proliferation and Migration in Cholangiocarcinoma via HAND1/Wnt/β-Catenin Signaling Pathway.
Wound Healing Effects of Dracontomelon dao on Bacterial Infection Wounds in Rats and Its Potential Mechanisms under Simulated Space Environment.
Ferroptosis-Specific Inhibitor Ferrostatin-1 Relieves H(2)O(2)-Induced Redox Imbalance in Primary Cardiomyocytes through the Nrf2/ARE Pathway.
ZNF165 Is Involved in the Regulation of Immune Microenvironment and Promoting the Proliferation and Migration of Hepatocellular Carcinoma by AhR/CYP1A1.
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m(6)A Modification of MAT2A Pre-mRNA by METTL16.
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Ferritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2'-Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester.
Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway.
The Oral Tumor Cell Exosome miR-10b Stimulates Cell Invasion and Relocation via AKT Signaling.
CPE Regulates Proliferation and Apoptosis of Primary Myocardial Cells Mediated by Ischemia and Hypoxia Injury.
Effects of Vitexin, a Natural Flavonoid Glycoside, on the Proliferation, Invasion, and Apoptosis of Human U251 Glioblastoma Cells.
Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke.
Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/eNOS Pathway.
Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.
Intermittent Hypoxia Inhibits Hepatic CYP1a2 Expression and Delays Aminophylline Metabolism.
Analysis of Therapeutic Targets of A Novel Peptide Athycaltide-1 in the Treatment of Isoproterenol-Induced Pathological Myocardial Hypertrophy.
Resveratrol Alleviates Skeletal Muscle Insulin Resistance by Downregulating Long Noncoding RNA.
Ketone Body β-Hydroxybutyrate Prevents Myocardial Oxidative Stress in Septic Cardiomyopathy.
Hydroxytyrosol Ameliorates Intervertebral Disc Degeneration and Neuropathic Pain by Reducing Oxidative Stress and Inflammation.
Mitochondria-Targeted Antioxidant Mitoquinone Maintains Mitochondrial Homeostasis through the Sirt3-Dependent Pathway to Mitigate Oxidative Damage Caused by Renal Ischemia/Reperfusion.
Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway.
Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway.
Identification of FABP7 as a Potential Biomarker for Predicting Prognosis and Antiangiogenic Drug Efficacy of Glioma.
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Tanshinone IIA Accomplished Protection against Radiation-Induced Cardiomyocyte Injury by Regulating the p38/p53 Pathway.
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
GNAI2 Is a Risk Factor for Gastric Cancer: Study of Tumor Microenvironment (TME) and Establishment of Immune Risk Score (IRS).
New inhibitors of cathepsin V impair tumor cell proliferation and elastin degradation and increase immune cell cytotoxicity.
FBXO17 Inhibits the Wnt/β-Catenin Pathway and Proliferation of Ishikawa Cells.
Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.
Yap is essential for uterine decidualization through Rrm2/GSH/ROS pathway in response to Bmp2.
TET1s deficiency exacerbates oscillatory shear flow-induced atherosclerosis.
4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis.
GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway.
Anp32e promotes renal interstitial fibrosis by upregulating the expression of fibrosis-related proteins.
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
DNA Polymerase Gamma Recovers Mitochondrial Function and Inhibits Vascular Calcification by Interacted with p53.
Rab31 promotes the invasion and metastasis of cervical cancer cells by inhibiting MAPK6 degradation.
Vocal changes in a zebra finch model of Parkinson's disease characterized by alpha-synuclein overexpression in the song-dedicated anterior forebrain pathway.
Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus.
Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress.
GPC2 deficiency inhibits cell growth and metastasis in colon adenocarcinoma.
Dezocine inhibits cell proliferation, migration, and invasion by targeting CRABP2 in ovarian cancer.
β2-Adrenergic receptor expression in subchondral bone of patients with varus knee osteoarthritis.
Superparamagnetic Iron Oxide Nanoparticles Protect Human Gingival Fibroblasts from Porphyromonas gingivalis Invasion and Inflammatory Stimulation.
Exosome Derived from Mesenchymal Stem Cells Alleviates Pathological Scars by Inhibiting the Proliferation, Migration and Protein Expression of Fibroblasts via Delivering miR-138-5p to Target SIRT1.
N-Methyl D-aspartate receptor subtype 2B/Ca(2+)/calmodulin-dependent protein kinase II signaling in the lateral habenula regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia.
Microglial infiltration mediates cognitive dysfunction in rat models of hypothalamic obesity via a hypothalamic-hippocampal circuit involving the lateral hypothalamic area.
Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death.
Endothelin-1, over-expressed in SOD1(G93A) mice, aggravates injury of NSC34-hSOD1G93A cells through complicated molecular mechanism revealed by quantitative proteomics analysis.
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
Receptor-Interacting Protein Kinase 3 Inhibition Relieves Mechanical Allodynia and Suppresses NLRP3 Inflammasome and NF-κB in a Rat Model of Spinal Cord Injury.
Adipose Dysfunction in Adulthood Insulin Resistance of Low-Birth Weight Mice: A Proteomics Study.
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
Beclin1 Deficiency Suppresses Epileptic Seizures.
TNF-α and IL-1β Promote Renal Podocyte Injury in T2DM Rats by Decreasing Glomerular VEGF/eNOS Expression Levels and Altering Hemodynamic Parameters.
Sodium Tanshinone IIA Sulfonate Inhibits Vascular Endothelial Cell Pyroptosis via the AMPK Signaling Pathway in Atherosclerosis.
C-X-C-Chemokine-Receptor-Type-4 Inhibitor AMD3100 Attenuates Pulmonary Inflammation and Fibrosis in Silicotic Mice.
Genome Wide Differential Expression Profiles in Nevus Sebaceous Uncovered Low Expression of CDKN2AIP and Construction of a ceRNA Network.
Palmitate Induces Mitochondrial Energy Metabolism Disorder and Cellular Damage via the PPAR Signaling Pathway in Diabetic Cardiomyopathy.
Endothelial Microparticles Derived from Primary Pulmonary Microvascular Endothelial Cells Mediate Lung Inflammation in Chronic Obstructive Pulmonary Disease by Transferring microRNA-126.
Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma.
Decitabine improves MMS-induced retinal photoreceptor cell damage by targeting DNMT3A and DNMT3B.
Pirfenidone Attenuates Renal Tubulointerstitial Fibrosis through Inhibiting miR-21.
A novel ferroptosis-related gene signature to predict overall survival in patients with osteosarcoma.
Probiotic Saccharomyces boulardii attenuates cardiopulmonary bypass-induced acute lung injury by inhibiting ferroptosis.
Over-expression of miR-193a-3p regulates the apoptosis of colorectal cancer cells by targeting PAK3.
Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
KLF16 Downregulates the Expression of Tumor Suppressor Gene TGFBR3 to Promote Bladder Cancer Proliferation and Migration.
METTL3 Facilitates Tumor Progression by COL12A1/MAPK Signaling Pathway in Esophageal Squamous Cell Carcinoma.
Promoter Methylation-Mediated NPTX2 Silencing Promotes Tumor Growth in Human Prostate Cancer.
Dietary choline, via gut microbe- generated trimethylamine-N- oxide, aggravates chronic kidney disease-induced cardiac dysfunction by inhibiting hypoxia-induced factor 1α.
Exploratory study of sea buckthorn enhancing QiangGuYin efficacy by inhibiting CKIP-1 and Notum activating the Wnt/β-catenin signaling pathway and analysis of active ingredients by molecular docking.
Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway.
Deciphering the active constituents of Dabushen decoction of ameliorating osteoarthritis via PPARγ preservation by targeting DNMT1.
Exploring the pharmacological mechanisms of icaritin against nasopharyngeal carcinoma via network pharmacology and experimental validation.
Signature construction and molecular subtype identification based on cuproptosis-related genes to predict the prognosis and immune activity of patients with hepatocellular carcinoma.
Indentification of novel MSTO1 compound heterozygous mutations in a Chinese family with recessive cerebellar atrophy and ataxia.
Comprehensive analysis for cellular senescence-related immunogenic characteristics and immunotherapy prediction of acute myeloid leukemia.
DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress.
Acacetin protects against depression-associated dry eye disease by regulating ubiquitination of NLRP3 through gp78 signal.
Identification of prognostic gene expression signatures based on the tumor microenvironment characterization of gastric cancer.
Macrophage malfunction in Triptolide-induced indirect hepatotoxicity.
Combinatorial suicide gene strategies for the safety of cell therapies.
LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2.
Screening and identification of tissue-infiltrating immune cells and genes for patients with emphysema phenotype of COPD.
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
Integrating network pharmacology and experimental validation to clarify the anti-hyperuricemia mechanism of cortex phellodendri in mice.
Shenkang injection improves chronic kidney disease by inhibiting multiple renin-angiotensin system genes by blocking the Wnt/β-catenin signalling pathway.
Identification of nine signature proteins involved in periodontitis by integrated analysis of TMT proteomics and transcriptomics.
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Hexavalent Chromium Exposure Induces Intestinal Barrier Damage via Activation of the NF-κB Signaling Pathway and NLRP3 Inflammasome in Ducks.
Aging-related features predict prognosis and immunotherapy efficacy in hepatocellular carcinoma.
Autoinducer-2 promotes Pseudomonas aeruginosa PAO1 acute lung infection via the IL-17A pathway.
Class IIa histone deacetylase inhibition ameliorates acute kidney injury by suppressing renal tubular cell apoptosis and enhancing autophagy and proliferation.
Pharmacological suppression of Nedd4-2 rescues the reduction of Kv11.1 channels in pathological cardiac hypertrophy.
Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects.
Involvement of integrin αvβ3 in thyroid hormone-induced dendritogenesis.
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
High Expression of ATP6V1C2 Predicts Unfavorable Overall Survival in Patients With Colon Adenocarcinoma.
Salusin-β, a TOR2A gene product, promotes proliferation, migration, fibrosis, and calcification of smooth muscle cells and accelerates the imbalance of vasomotor function and vascular remodeling in monocrotaline-induced pulmonary hypertensive rats.
GSK3β-dependent lysosome biogenesis: An effective pathway to mitigate renal fibrosis with LM49.
Jian-Pi-Yi-Shen Formula Improves Adenine-Induced Chronic Kidney Disease via Regulating Tryptophan Metabolism and Aryl Hydrocarbon Receptor Signaling.
Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation.
Dao-Chi Powder Ameliorates Pancreatitis-Induced Intestinal and Cardiac Injuries via Regulating the Nrf2-HO-1-HMGB1 Signaling Pathway in Rats.
Clostridium butyricum Protects Against Pancreatic and Intestinal Injury After Severe Acute Pancreatitis via Downregulation of MMP9.
Persistent Activation of Autophagy After Cisplatin Nephrotoxicity Promotes Renal Fibrosis and Chronic Kidney Disease.
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Establishment and Phenotypic Analysis of the Novel Gaucher Disease Mouse Model With the Partially Humanized Gba1 Gene and F213I Mutation.
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Dihydroarteannuin Ameliorates Collagen-Induced Arthritis Via Inhibiting B Cell Activation by Activating the FcγRIIb/Lyn/SHP-1 Pathway.
C/EBPα Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus.
NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen Species.
Theabrownin and Poria cocos Polysaccharide Improve Lipid Metabolism via Modulation of Bile Acid and Fatty Acid Metabolism.
Emodin Ameliorates Acute Pancreatitis-Associated Lung Injury Through Inhibiting the Alveolar Macrophages Pyroptosis.
Long-Acting β(2) Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis.
MiR-103a-3p Promotes Zika Virus Replication by Targeting OTU Deubiquitinase 4 to Activate p38 Mitogen-Activated Protein Kinase Signaling Pathway.
RGMa Participates in the Blood-Brain Barrier Dysfunction Through BMP/BMPR/YAP Signaling in Multiple Sclerosis.
Comprehensive Analysis of circRNAs, miRNAs, and mRNAs Expression Profiles and ceRNA Networks in Decidua of Unexplained Recurrent Spontaneous Abortion.
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Prognostic Biomarker KIF18A and Its Correlations With Immune Infiltrates and Mitosis in Glioma.
Identification of Polysaccharides From Dipsacus asperoides and Their Effects on Osteoblast Proliferation and Differentiation in a High-Glucose Environment.
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
The Role of P4HA1 in Multiple Cancer Types and its Potential as a Target in Renal Cell Carcinoma.
Dendrobium Nobile Lindl. Alkaloid Suppresses NLRP3-Mediated Pyroptosis to Alleviate LPS-Induced Neurotoxicity.
Pan-cancer analysis of ASB3 and the potential clinical implications for immune microenvironment of glioblastoma multiforme.
Vitamin D Deficiency Impacts Exposure and Response of Pravastatin in Male Rats by Altering Hepatic OATPs.
SHP2 Inhibitors Show Anti-Myeloma Activity and Synergize With Bortezomib in the Treatment of Multiple Myeloma.
Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.
Cyclophosphamide Induces the Ferroptosis of Tumor Cells Through Heme Oxygenase-1.
Protein Disulfide-Isomerase A3 Is a Robust Prognostic Biomarker for Cancers and Predicts the Immunotherapy Response Effectively.
Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4.
Acute Administration of Metformin Protects Against Neuronal Apoptosis Induced by Cerebral Ischemia-Reperfusion Injury via Regulation of the AMPK/CREB/BDNF Pathway.
The Role of the Negative Regulation of Microglia-Mediated Neuroinflammation in Improving Emotional Behavior After Epileptic Seizures.
Cochlear Marginal Cell Pyroptosis Is Induced by Cisplatin via NLRP3 Inflammasome Activation.
Baohuoside I Inhibits Tumor Angiogenesis in Multiple Myeloma via the Peroxisome Proliferator-Activated Receptor γ/Vascular Endothelial Growth Factor Signaling Pathway.
Tanreqing Injection Attenuates Macrophage Activation and the Inflammatory Response via the lncRNA-SNHG1/HMGB1 Axis in Lipopolysaccharide-Induced Acute Lung Injury.
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Role of Suprabasin in the Dedifferentiation of Follicular Epithelial Cell-Derived Thyroid Cancer and Identification of Related Immune Markers.
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps.
Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopausal Mice.
Pan-Cancer Analysis Reveals a Distinct Neutrophil Extracellular Trap-Associated Regulatory Pattern.
Atractylenolide III Attenuates Angiogenesis in Gastric Precancerous Lesions Through the Downregulation of Delta-Like Ligand 4.
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway.
NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.
Natural product manoalide promotes EGFR-TKI sensitivity of lung cancer cells by KRAS-ERK pathway and mitochondrial Ca(2+) overload-induced ferroptosis.
Desmosterol: A natural product derived from macroalgae modulates inflammatory response and oxidative stress pathways in intestinal epithelial cells.
Exploration and validation of a combined immune and metabolism gene signature for prognosis prediction of colorectal cancer.
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells.
Calcitriol-enhanced autophagy in gingival epithelium attenuates periodontal inflammation in rats with type 2 diabetes mellitus.
ADAR1 promotes systemic sclerosis via modulating classic macrophage activation.
MLN2238 exerts its anti-tumor effects via regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma.
Berberine prevents lethal EV71 neurological infection in newborn mice.
Ginsenoside Rg1 interferes with the progression of diabetic osteoporosis by promoting type H angiogenesis modulating vasculogenic and osteogenic coupling.
Effects of scoparone on non-alcoholic fatty liver disease revealed by RNA sequencing.
Characterization and subcellular localization of Alongshan virus proteins.
Fibroblast activation protein α activatable theranostic pro-photosensitizer for accurate tumor imaging and highly-specific photodynamic therapy.
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway.
RNA N(6) -methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer.
CPSF1 positively regulates NSDHL by alternative polyadenylation and promotes gastric cancer progression.
WWOX-rs13338697 genotype predicts therapeutic efficacy of ADI-PEG 20 for patients with advanced hepatocellular carcinoma.
Combined treatment of marizomib and cisplatin modulates cervical cancer growth and invasion and enhances antitumor potential in vitro and in vivo.
PKIB involved in the metastasis and survival of osteosarcoma.
A comprehensive role evaluation and mechanism exploration of POGLUT2 in pan-cancer.
Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11.
The Novel LncRNA WASH5P Inhibits Colorectal Cancer Carcinogenesis via Targeting AKT Signaling Pathway.
FOSL1 promotes tumor growth and invasion in ameloblastoma.
Cold Atmospheric Plasma Conveys Selectivity Against Hepatocellular Carcinoma Cells via Triggering EGFR(Tyr1068)-Mediated Autophagy.
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Integrative Proteo-Genomic Analysis for Recurrent Survival Prognosis in Colon Adenocarcinoma.
A miR-137-XIAP axis contributes to the sensitivity of TRAIL-induced cell death in glioblastoma.
Establishment of a Transient and Stable Transfection System for Babesia duncani Using a Homologous Recombination Strategy.
Agonists Specific for κ-Opioid Receptor Induces Apoptosis of HCC Cells Through Enhanced Endoplasmic Reticulum Stress.
The Novel lncRNA RP9P Promotes Colorectal Cancer Progression by Modulating miR-133a-3p/FOXQ1 Axis.
MiR-29b-3p Inhibits Migration and Invasion of Papillary Thyroid Carcinoma by Downregulating COL1A1 and COL5A1.
Cyclin-Dependent Kinase Inhibitors Function as Potential Immune Regulators via Inducing Pyroptosis in Triple Negative Breast Cancer.
LncRNA SNHG1 Promotes the Progression of Pancreatic Cancer by Regulating FGFR1 Expression via Competitively Binding to miR-497.
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
GNG12 as A Novel Molecular Marker for the Diagnosis and Treatment of Glioma.
A mitochondria-related signature for predicting immune microenvironment and therapeutic response in osteosarcoma.
High expression of RARG accelerates ovarian cancer progression by regulating cell proliferation.
NUF2 overexpression contributes to epithelial ovarian cancer progression via ERBB3-mediated PI3K-AKT and MAPK signaling axes.
Establishment and experimental validation of a novel cuproptosis-related gene signature for prognostic implication in cholangiocarcinoma.
BTG2 suppresses renal cell carcinoma progression through N6-methyladenosine.
PUS1 is a novel biomarker for predicting poor outcomes and triple-negative status in breast cancer.
Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo.
IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability.
Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer.
G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice.
Long noncoding RNA Gm31629 promotes bone regeneration by maintaining bone marrow mesenchymal stem cells activity.
Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress.
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
ATP11A promotes EMT by regulating Numb PRR(L) in pancreatic cancer cells.
7,8-Dihydroxyflavone protects neurons against oxygen-glucose deprivation induced apoptosis and activates the TrkB/Akt pathway.
Long-term environmental exposure of darkness induces hyperandrogenism in PCOS via melatonin receptor 1A and aromatase reduction.
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Inflammatory Microenvironment Accelerates Bone Marrow Mesenchymal Stem Cell Aging.
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Identification of KIF23 as a Prognostic Biomarker Associated With Progression of Clear Cell Renal Cell Carcinoma.
Potassium Titanate Assembled Titanium Dioxide Nanotube Arrays Endow Titanium Implants Excellent Osseointegration Performance and Nerve Formation Potential.
A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia.
Stimulator of Interferon Genes (STING) Promotes Staphylococcus aureus-Induced Extracellular Traps Formation via the ROS-ERK Signaling Pathway.
HIF-1α Regulates Osteogenesis of Periosteum-Derived Stem Cells Under Hypoxia Conditions via Modulating POSTN Expression.
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis.
Tetrahydropalmatine induces the polarization of M1 macrophages to M2 to relieve limb ischemia-reperfusion-induced lung injury via inhibiting the TLR4/NF-κB/NLRP3 signaling pathway.
Phospholipase A/acyltransferase 4 is a prognostic biomarker and correlated with immune infiltrates in pancreatic cancer.
JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia.
Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway.
HIF‑1α and MBP1 are associated with the progression of breast cancer cells by repressing β‑catenin transcription.
Establishment and application of a human osteosarcoma U-2OS cell line that can stably express Cas9 protein.
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway.
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
LINC01140 regulates osteosarcoma proliferation and invasion by targeting the miR-139-5p/HOXA9 axis.
Overexpression of MCAM induced by SMYD2-H3K36me2 in breast cancer stem cell properties.
E3 ubiquitin ligase RNF6 promotes antiviral immune responses through enhancing the expression of interferon stimulated genes in myeloid cells.
Protective effects of budesonide on LPS-induced podocyte injury by modulating macrophage M1/M2 polarization: Evidence from in vitro and in silico studies.
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus.
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Lactate inhibits osteogenic differentiation of human periodontal ligament stem cells via autophagy through the MCT1-mTOR signaling pathway.
Hylocereus undatus flower extract suppresses OVA-induced allergic asthma in BALb/c mice by reducing airway inflammation and modulating gut microbiota.
Complement factor B inhibitor LNP023 improves lupus nephritis in MRL/lpr mice.
NLRP3 inflammasome contributes to endothelial dysfunction in angiotensin II-induced hypertension in mice.
Increased IRF9-STAT2 Signaling Leads to Adaptive Resistance toward Targeted Therapy in Melanoma by Restraining GSDME-Dependent Pyroptosis.
The pH sensor and ion binding of NhaD Na(+) /H(+) antiporter from IT superfamily.
FEK self-assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening.
Shexiang Baoxin Pill attenuates myocardial ischemia/reperfusion injury by activating autophagy via modulating the ceRNA-Map3k8 pathway.
Novel mutations of PMFBP1 in a man with acephalic spermatozoa defects.
Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37.
1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway.
ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli.
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model.
PIM1 promotes hepatic conversion by suppressing reprogramming-induced ferroptosis and cell cycle arrest.
Multimodal cotranslational interactions direct assembly of the human multi-tRNA synthetase complex.
HDAC3 of dorsal hippocampus induces postoperative cognitive dysfunction in aged mice.
Hawk Tea Flavonoids as Natural Hepatoprotective Agents Alleviate Acute Liver Damage by Reshaping the Intestinal Microbiota and Modulating the Nrf2 and NF-κB Signaling Pathways.
MicroRNA-20a-5p regulates the epithelial-mesenchymal transition of human hepatocellular carcinoma by targeting RUNX3.
Emodin regulates the autophagy via the miR-371a-5p/PTEN axis to inhibit hepatic malignancy.
Effects of Let-7c on the processing of hepatitis B virus associated liver diseases.
Expression and Prognostic Value of Chromobox Family Proteins in Esophageal Cancer.
Boosting cisplatin chemotherapy by nanomotor-enhanced tumor penetration and DNA adducts formation.
Transmissible Gastroenteritis Virus Infection Promotes the Self-Renewal of Porcine Intestinal Stem Cells via Wnt/β-Catenin Pathway.
Duck Tembusu Virus Inhibits Type I Interferon Production through the JOSD1-SOCS1-IRF7 Negative-Feedback Regulation Pathway.
Identification of Host Factors Differentially Induced by Clinically Diverse Strains of Tick-Borne Encephalitis Virus.
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.
Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy.
ACACB is a novel metabolism-related biomarker in the prediction of response to cetuximab therapy inmetastatic colorectal cancer.
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology.
A novel 2B4 receptor leads to worse pregnancy outcomes by facilitating TNF-α and IFN-γ production in dNK cells during Toxoplasma gondii infection.
Co-Targeting ErbB Receptors and the PI3K/AKT Axis in Androgen-Independent Taxane-Sensitive and Taxane-Resistant Human Prostate Cancer Cells.
Realgar Alleviated Neuroinflammation Induced by High Protein and High Calorie Diet in Rats via the Microbiota-Gut-Brain Axis.
Effects of Moderate-Intensity Continuous Training and High-Intensity Interval Training on Testicular Oxidative Stress, Apoptosis and m6A Methylation in Obese Male Mice.
Effects of plant-based medicinal food on postoperative recurrence and lung metastasis of gastric cancer regulated by Wnt/β-catenin-EMT signaling pathway and VEGF-C/D-VEGFR-3 cascade in a mouse model.
The Immune Subtypes and Landscape of Advanced-Stage Ovarian Cancer.
The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma.
Isosteviol sodium attenuates high fat/high cholesterol-induced myocardial dysfunction by regulating the Sirt1/AMPK pathway.
R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization.
Proteomic analysis reveals that ACSL4 activation during reflux esophagitis contributes to ferroptosis-mediated esophageal mucosal damage.
Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.
Study of differential proteomics in granulosa cells of premature ovarian insufficiency (POI) and the roles and mechanism of RAC1 in granulosa cells.
Small extracellular vesicles derived from hypoxic mesenchymal stem cells promote vascularized bone regeneration through the miR-210-3p/EFNA3/PI3K pathway.
African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.
Sinomenine Hydrochloride Promotes TSHR-Dependent Redifferentiation in Papillary Thyroid Cancer.
Construction of tandem diabody (IL-6/CD20)-secreting human umbilical cord mesenchymal stem cells and its experimental treatment on diffuse large B cell lymphoma.
NMR-Based Metabolomic Analysis for the Effects of Trimethylamine N-Oxide Treatment on C2C12 Myoblasts under Oxidative Stress.
Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas.
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
RO4929097, a Selective γ-Secretase Inhibitor, Inhibits Subretinal Fibrosis Via Suppressing Notch and ERK1/2 Signaling in Laser-Induced Mouse Model.
PLIN2 promotes HCC cells proliferation by inhibiting the degradation of HIF1α.
Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells.
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
The Prevention and Reversal of a Phenytoin-Resistant Model by N-acetylcysteine Therapy Involves the Nrf2/P-Glycoprotein Pathway at the Blood-Brain Barrier.
Growth hormone inhibits adipogenic differentiation and induces browning in bovine subcutaneous adipocytes.
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2.
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia.
Hippocampal Inhibitory Synapsis Deficits Induced by α5-Containing GABA(A) Receptors Mediate Chronic Neuropathic Pain-Related Cognitive Impairment.
Expression patterns and correlation analyses of muscle-specific genes in the process of sheep myoblast differentiation.
Ferroportin-dependent ferroptosis induced by ellagic acid retards liver fibrosis by impairing the SNARE complexes formation.
TGF-β1 peptide-based inhibitor P144 ameliorates renal fibrosis after ischemia-reperfusion injury by modulating alternatively activated macrophages.
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.
Comparison of DNA stability and its related genes of neurons derived from induced pluripotent stem cells and primary retinal neurons.
Dapagliflozin Alleviates Coxsackievirus B3-induced Acute Viral Myocarditis by Regulating the Macrophage Polarization Through Stat3-related Pathways.
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Circadian clock gene BMAL1 inhibits the proliferation and tumor-formation ability of nasopharyngeal carcinoma cells and increases the sensitivity of radiotherapy.
Rottlerin plays an antiviral role at early and late steps of Zika virus infection.
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
The influence of different proton pump inhibitors and potassium-competitive acid blockers on indomethacin-induced small intestinal injury.
ICAT promotes colorectal cancer metastasis via binding to JUP and activating the NF-κB signaling pathway.
A single-beam of light priming the immune responses and boosting cancer photoimmunotherapy.
Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway.
TSP1 promotes fibroblast proliferation and extracellular matrix deposition via the IL6/JAK2/STAT3 signalling pathway in keloids.
Peptide OM-LV20 protects astrocytes against oxidative stress via the 'PAC1R/JNK/TPH1' axis.
Downregulation of EZH2 in Trophoblasts Induces Decidual M1 Macrophage Polarization: a Potential Cause of Recurrent Spontaneous Abortion.
The HN1/HMGB1 axis promotes the proliferation and metastasis of hepatocellular carcinoma and attenuates the chemosensitivity to oxaliplatin.
SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.
Syce1 and Syce3 regulate testosterone and dihydrotestosterone synthesis via steroidogenic pathways in mouse Sertoli and Leydig cells.
The SIRT1 activator SRT2104 promotes BMP9-induced osteogenic and angiogenic differentiation in mesenchymal stem cells.
Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin α7 is counteracted by TBK1-p62 axis-mediated autophagy.
Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid-β oligomers.
The anti-inflammatory effect of vasoactive peptides from soybean protein hydrolysates by mediating serum extracellular vesicles-derived miRNA-19b/CYLD/TRAF6 axis in the vascular microenvironment of SHRs.
Black mulberry (Morus nigra) fruit extract alleviated AD-Like symptoms induced by toxic Aβ protein in transgenic Caenorhabditis elegans via insulin DAF-16 signaling pathway.
Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway.
Electroacupuncture at PC6 (Neiguan) Attenuates Angina Pectoris in Rats with Myocardial Ischemia-Reperfusion Injury Through Regulating the Alternative Splicing of the Major Inhibitory Neurotransmitter Receptor GABRG2.
Long non-coding RNA VAL facilitates PKM2 enzymatic activity to promote glycolysis and malignancy of gastric cancer.
Emodin attenuates severe acute pancreatitis-associated acute lung injury by suppressing pancreatic exosome-mediated alveolar macrophage activation.
Frequently expressed glypican-3 as a promising novel therapeutic target for osteosarcomas.
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Investigation into the anti-airway inflammatory role of the PI3Kγ inhibitor JN-PK1: An in vitro and in vivo study.
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
Investigation of novel de novo KCNC2 variants causing severe developmental and early-onset epileptic encephalopathy.
The propofol-induced mitochondrial damage in fetal rat hippocampal neurons via the AMPK/P53 signaling pathway.
Nobiletin Prevents D-Galactose-Induced C2C12 Cell Aging by Improving Mitochondrial Function.
ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer.
Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice.
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
HDAC1 in the Ovarian Granulosa Cells of Tan Sheep Improves Cumulus Cell Expansion and Oocyte Maturation Independently of the EGF-like Growth Factors.
Transcriptomic Analysis Reveals Lactobacillus reuteri Alleviating Alcohol-Induced Liver Injury in Mice by Enhancing the Farnesoid X Receptor Signaling Pathway.
Haizao Yuhu decoctions including three species of glycyrrhiza protected against propylthiouracil-induced goiter with hypothyroidism in rats via the AMPK/mTOR pathway.
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
IGF2BP2 Promotes Epithelial to Mesenchymal Transition and Metastasis through Stabilizing HMGA1 mRNA in Gastric Cancer.
Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss.
CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment.
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
Integrated multi-omics approach revealed cellular senescence landscape.
A network pharmacology-based study on the mechanism of astragaloside IV alleviating renal fibrosis through the AKT1/GSK-3β pathway.
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Equus β-Defensin-1 Regulates Innate IMMUNE Response in S. aureus-Infected Mouse Monocyte Macrophage.
Long-Term Protein Restriction Modulates Lipid Metabolism in White Adipose Tissues and Alters Colonic Microbiota of Shaziling Pigs.
Berberine mitigates hepatic insulin resistance by enhancing mitochondrial architecture via the SIRT1/Opa1 signalling pathway.
A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis.
Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1.
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
DDX17 promotes the growth and metastasis of lung adenocarcinoma.
Analysis of RIOK2 Functions in Mediating the Toxic Effects of Deoxynivalenol in Porcine Intestinal Epithelial Cells.
Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity.
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Lack of NPR1 Increases Vascular Endothelial Adhesion through Induction of Integrin Beta 4.
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice.
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis.
MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats.
KLK12 Regulates MMP-1 and MMP-9 via Bradykinin Receptors: Biomarkers for Differentiating Latent and Active Bovine Tuberculosis.
Transcriptional Responses of Copper-Transport-Related Genes ctr1, ctr2 and atox1 and Their Roles in the Regulation of Cu Homeostasis in Yellow Catfish Pelteobagrus fulvidraco.
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H(2)O(2)-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
The Mixture of Ferulic Acid and P-Coumaric Acid Suppresses Colorectal Cancer through lncRNA 495810/PKM2 Mediated Aerobic Glycolysis.
MicroRNA-223 negatively regulates the osteogenic differentiation of periodontal ligament derived cells by directly targeting growth factor receptors.
Accelerated Bone Regeneration by an Astaxanthin-Modified Antioxidant Aerogel through Relieving Oxidative Stress via the NRF2 Signaling Pathway.
Stain-Free total-protein normalization enhances the reproducibility of Western blot data.
NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Neutrophil extracellular traps accelerate vascular smooth muscle cell proliferation via Akt/CDKN1b/TK1 accompanying with the occurrence of hypertension.
Pharmacological inhibition of the cGAS-STING signaling pathway suppresses microglial M1-polarization in the spinal cord and attenuates neuropathic pain.
CPNE1 silencing inhibits cell proliferation and accelerates apoptosis in human gastric cancer.
MORC3 restricts human cytomegalovirus infection by suppressing the major immediate-early promoter activity.
The mitochondrial enzyme FAHD1 regulates complex II activity in breast cancer cells and is indispensable for basal BT-20 cells in vitro.
Pathogenic effects of Desulfovibrio in the gut on fatty liver in diet-induced obese mice and children with obesity.
Long noncoding RNA SNHG8 promotes chemoresistance in gastric cancer via binding with hnRNPA1 and stabilizing TROY expression.
[Effects of Long-Term Ethanol Consumption on Learning-Memory Functions in Mice and the Mechanisms Involved].
Expression analysis and functional characterization of thioredoxin domain-containing protein 11.
RNA-Seq approach to investigate the effects of melatonin on bone marrow-derived dendritic cells from dextran sodium sulfate-induced colitis mice.
Impaired autophagy and mitochondrial dynamics are involved in Sorafenib-induced cardiomyocyte apoptosis.
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Estrogen receptor variant ER-α36 facilitates estrogen signaling via EGFR in glioblastoma.
Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis.
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Roles of C/EBP-homologous protein and histone H3 lysine 4 methylation in arsenic-induced mitochondrial apoptosis in hepatocytes.
Cadmium exposure induces autophagy via PLC-IP(3) -IP(3) R signaling pathway in duck renal tubular epithelial cells.
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment.
Metabolomic Analysis Reveals that SPHK1 Promotes Oral Squamous Cell Carcinoma Progression through NF-κB Activation.
Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFβ/SMADs signaling pathway.
SIRT3 expression alleviates microglia activation‑induced dopaminergic neuron injury through the mitochondrial pathway.
Human gingival mesenchymal stem cells improve movement disorders and tyrosine hydroxylase neuronal damage in Parkinson disease rats.
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease.
Galactosylceramidase deficiency and pathological abnormalities in cerebral white matter of Krabbe disease.
Maizediterpene D from the roots of Zea mays L. alleviates hydrogen peroxide induced oxidative stress and improves cell survival by activation of TrkB/IGF-1R crosstalk pathways.
Elevated Notch-1 expression promotes the lymph node metastasis of gastric cancer and the Notch-1-PTEN-ERK1/2 signalling axis promotes the progression of gastric cancer.
1-Deoxynojirimycin attenuates septic cardiomyopathy by regulating oxidative stress, apoptosis, and inflammation via the JAK2/STAT6 signaling pathway.
Postnatal state transition of cardiomyocyte as a primary step in heart maturation.
Astragalin mitigates inflammatory osteolysis by negatively modulating osteoclastogenesis via ROS and MAPK signaling pathway.
Grossamide attenuates inflammation by balancing macrophage polarization through metabolic reprogramming of macrophages in mice.
Long non-coding RNA DLGAP1-AS1 modulates the development of non-small-cell lung cancer via the microRNA-193a-5p/DTL axis.
Effect of crosstalk between Th17 and Th9 cells on the activation of dermal vascular smooth muscle cells in systemic scleroderma and regulation of tanshinone IIA.
Meiotic nuclear divisions 1 promotes proliferation and metastasis in hepatocellular carcinoma and is a potential diagnostic and therapeutic target gene.
Pirfenidone-loaded exosomes derived from pancreatic ductal adenocarcinoma cells alleviate fibrosis of premetastatic niches to inhibit liver metastasis.
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.
The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia.
FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway.
Vaccination with a shared oncogenic tumor-self antigen elicits a population of CD8+ T cells with a regulatory phenotype.
Dipsacoside B Inhibits the Migration and Proliferation of VSMCs and Blunts Neointimal Formation by Upregulating PTEN Expression.
Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation.
Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study.
An RNAi screen of RNA helicases identifies eIF4A3 as a regulator of embryonic stem cell identity.
Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway.
Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats.
Bombesin receptor-activated protein exacerbates cisplatin-induced AKI by regulating the degradation of SIRT2.
VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway.
Antitumor Activity and Mechanism of Action of the Antimicrobial Peptide AMP-17 on Human Leukemia K562 Cells.
The Crosstalk between HepG2 and HMC-III Cells: In Vitro Modulation of Gene Expression with Conditioned Media.
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Follicle-Stimulating Hormone Promotes the Development of Endometrial Cancer In Vitro and In Vivo.
Trpc5-regulated AMPKα/mTOR autophagy pathway is associated with glucose metabolism disorders in low birth weight mice under overnutrition.
Dual Inhibition of BRAF-MAPK and STAT3 Signaling Pathways in Resveratrol-Suppressed Anaplastic Thyroid Cancer Cells with BRAF Mutations.
Self-assembly of DNA nanostructure containing cell-specific aptamer as a precise drug delivery system for cancer therapy in non-small cell lung cancer.
TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals.
JMJD1C Regulates Megakaryopoiesis in In Vitro Models through the Actin Network.
Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci.
SOX4 Mediates ATRA-Induced Differentiation in Neuroblastoma Cells.
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC.
"All-in-One" Exosome Engineering Strategy for Effective Therapy of Familial Hypercholesterolemia.
The long noncoding RNA TINCR promotes self-renewal of human liver cancer stem cells through autophagy activation.
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Jatrorrhizine from Rhizoma Coptidis exerts an anti-obesity effect in db/db mice.
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Luteolin can ameliorate renal interstitial fibrosis-induced renal anaemia through the SIRT1/FOXO3 pathway.
Lactate Activates AMPK Remodeling of the Cellular Metabolic Profile and Promotes the Proliferation and Differentiation of C2C12 Myoblasts.
Stress-induced reduction of Na(+)/H(+) exchanger isoform 1 promotes maladaptation of neuroplasticity and exacerbates depressive behaviors.
Brca1 Is Regulated by the Transcription Factor Gata3, and Its Silencing Promotes Neural Differentiation in Retinal Neurons.
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway.
G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway.
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Molecular and functional characterization of teleost-specific Interleukin-17N in yellow catfish (Pelteobagrus fulvidraco).
MiR-18 inhibitor promotes the differentiation of bovine skeletal muscle-derived satellite cells by increasing MEF2D expression.
Salidroside inhibits doxorubicin-induced cardiomyopathy by modulating a ferroptosis-dependent pathway.
Trillin inhibits myoblast differentiation via increasing autophagy.
Mechanical force-sensitive lncRNA SNHG8 inhibits osteogenic differentiation by regulating EZH2 in hPDLSCs.
TREM2 ameliorates anesthesia and surgery-induced cognitive impairment by regulating mitophagy and NLRP3 inflammasome in aged C57/BL6 mice.
Role of thioredoxin-interacting protein in mediating endothelial dysfunction in hypertension.
Cadmium exposure suppresses insulin secretion through mtROS-mediated mitochondrial dysfunction and inflammatory response in pancreatic beta cells.
Exosomes derived from olfactory ensheathing cells provided neuroprotection for spinal cord injury by switching the phenotype of macrophages/microglia.
Effects of BMAL1 on dentinogenic differentiation of dental pulp stem cells via PI3K/Akt/mTOR pathway.
Heterozygote loss-of-function variants in the LRP5 gene cause familial exudative vitreoretinopathy.
CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling.
Neuregulin-1 promotes the proliferation, migration, and angiogenesis of human periodontal ligament stem cells in vitro.
Guanylate-binding Protein 2 Expression Is Associated With Poor Survival and Malignancy in Clear-cell Renal Cell Carcinoma.
Activated Phosphoinositide 3-Kinase δ Syndrome: a Large Pediatric Cohort from a Single Center in China.
Polyvinylamine with moderate binding affinity as a highly effective vehicle for RNA delivery.
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy.
Combination of ruthenium (II) polypyridyl complex Δ-Ru1 and Taxol enhances the anti-cancer effect on Taxol-resistant cancer cells through Caspase-1/GSDMD-mediated pyroptosis.
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Diminished Piezo2-Dependent Tactile Sensitivity Occurs in Aging Human Gut and Slows Gastrointestinal Transit in Mice.
Naringenin promoted spinal microglia M2 polarization in rat model of cancer-induced bone pain via regulating AMPK/PGC-1α signaling axis.
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Long non-coding RNA H19 alleviates hippocampal damage in convulsive status epilepticus rats through the nuclear factor-kappaB signaling pathway.
Chemokine (C-C motif) ligand 18/membrane-associated 3/forkhead box O1 axis promotes the proliferation, migration, and invasion of intrahepatic cholangiocarcinoma.
Methyltransferase like 7B is upregulated in sepsis and modulates lipopolysaccharide-induced inflammatory response and macrophage polarization.
Disheveled binding antagonist of β-catenin 1 interacted with β-catenin and connexin 43 in human-induced pluripotent stem cells-derived cardiomyocytes.
SNF5 promotes cell proliferation and immune evasion in non-small cell lung cancer.
Elevated BTG2 improves the radiosensitivity of non-small cell lung cancer (NSCLC) through apoptosis.
miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway.
m6A and YTHDF proteins contribute to the localization of select neuronal mRNAs.
ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling.
The anti-tumor effect of proteasome inhibitor MG132 for human adenoid cystic carcinoma: correlate with the emerging role of Nrf2/Keap1 signaling pathway.
Maelstrom promotes tumor metastasis through regulation of FGFR4 and epithelial-mesenchymal transition in epithelial ovarian cancer.
Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1.
Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.
Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.
GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer.
CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells.
Inhibition of the P2X7/NLRP3 Inflammasome Signaling Pathway by Deacetylgedunin from Toona sinensis.
del Nido cardioplegia better preserves cardiac diastolic function but histidine-tryptophan-ketoglutarate is better for endothelial function.
Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.
GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome.
Alanyl-Glutamine Protects against Lipopolysaccharide-Induced Liver Injury in Mice via Alleviating Oxidative Stress, Inhibiting Inflammation, and Regulating Autophagy.
Neural Stem Cell-Derived Exosomal Netrin1 Contributes to Neuron Differentiation of Mesenchymal Stem Cells in Therapy of Spinal Bifida Aperta.
Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages.
Resveratrol pretreatment protects neurons from oxygen-glucose deprivation/reoxygenation and ischemic injury through inhibiting ferroptosis.
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia.
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
Increased expression of prokineticin 2 and its receptor in endometrium of recurrent implantation failure patients decreased the expression of MMP9 important for decidualization.
Chlamydia psittaci Induces Autophagy in Human Bronchial Epithelial Cells via PERK and IRE1α, but Not ATF6 Pathway.
α5-nAChR associated with Ly6E modulates cell migration via TGF-β1/Smad signaling in non-small cell lung cancer.
G-CSF upregulates the expression of aquaporin-9 through CEBPB to enhance the cytotoxic activity of arsenic trioxide to acute myeloid leukemia cells.
Comparative Proteomic Analysis Reveals the Effect of Selenoprotein W Deficiency on Oligodendrogenesis in Fear Memory.
Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations.
Hippocampal NR6A1 impairs CREB-BDNF signaling and leads to the development of depression-like behaviors in mice.
Molecular cloning, characterization, and expression analysis of TIPE1 in chicken (Gallus gallus): Its applications in fatty liver hemorrhagic syndrome.
Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration.
Extracellular vesicles from the inflammatory microenvironment regulate the osteogenic and odontogenic differentiation of periodontal ligament stem cells by miR-758-5p/LMBR1/BMP2/4 axis.
Xiao-Luo-Wan treats propylthiouracil-induced goiter with hypothyroidism in rats through the PI3K-AKT/RAS pathways based on UPLC/MS and network pharmacology.
Network pharmacology analysis uncovers the effect on apoptotic pathway by Bu-Fei formula for COPD treatment.
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Novel variant of ETFDH leading to multiple acyl-CoA dehydrogenase deficiency by promoting protein degradation via ubiquitin proteasome pathway.
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma.
Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid.
CD14 Involvement in Third-degree Skin Burn-induced Myocardial Injury via the MAPK Signaling Pathway.
Repair of Spinal Cord Injury by Inhibition of PLK4 Expression Through Local Delivery of siRNA-Loaded Nanoparticles.
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.
Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression.
M(6)A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression.
2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis in mice by interfering with the ER-Nrf1-Tfam-mitochondria pathway.
Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy.
Acetylation-dependent SAGA complex dimerization promotes nucleosome acetylation and gene transcription.
SRSF3 facilitates replication of influenza A virus via binding and promoting the transport of viral mRNA.
Lysophosphatidic acid receptor 6 regulated by miR-27a-3p attenuates tumor proliferation in breast cancer.
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Immune-responsive gene 1 protects against liver injury caused by concanavalin A via the activation Nrf2/HO-1 pathway and inhibition of ROS activation pathways.
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
Inhibition of ROCK2 kinase activity improved behavioral deficits and reduced neuron damage in a DEACMP rat model.
SNF5, a core subunit of SWI/SNF complex, regulates melanoma cancer cell growth, metastasis, and immune escape in response to matrix stiffness.
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression.
Secreted gingipains from Porphyromonas gingivalis increase permeability in human cerebral microvascular endothelial cells through intracellular degradation of tight junction proteins.
Caecal microbiota could effectively increase chicken growth performance by regulating fat metabolism.
Ablation of Plasma Prekallikrein Decreases Low-Density Lipoprotein Cholesterol by Stabilizing Low-Density Lipoprotein Receptor and Protects Against Atherosclerosis.
Rab31 promotes activation of hepatic stellate cells by accelerating TGF-β receptor II complex endocytosis.
IL-10 Dysregulation Underlies Chemokine Insufficiency, Delayed Macrophage Response, and Impaired Healing in Diabetic Wounds.
Corresponding Changes of Autophagy-Related Genes and Proteins in Different Stages of Knee Osteoarthritis: An Animal Model Study.
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2.
The effects of modified RNA-binding proteins HuR on the biological behavior of the bladder cancer T24 cell line.
Dopamine D3 receptor in the nucleus accumbens alleviates neuroinflammation in a mouse model of depressive-like behavior.
Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn's disease.
Peritoneal dialysis effluent-derived exosomal miR-432-5p: an assessment tool for peritoneal dialysis efficacy.
Trimetazidine and exercise offer analogous improvements to the skeletal muscle insulin resistance of mice through Nrf2 signaling.
Novel insights into the mechanisms by which lncRNA HOTAIR regulates migration and invasion in HeLa cells.
Human Cytomegalovirus Hijacks WD Repeat Domain 11 for Virion Assembly Compartment Formation and Virion Morphogenesis.
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8(+) T cell responses.
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Bergamottin promotes osteoblast differentiation and bone formation via activating the Wnt/β-catenin signaling pathway.
Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 male mice.
Bisphenol A drives di(2-ethylhexyl) phthalate promoting thyroid tumorigenesis via regulating HDAC6/PTEN and c-MYC signaling.
Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.
Loss of NPPA-AS1 promotes heart regeneration by stabilizing SFPQ-NONO heteromer-induced DNA repair.
miR-30a targets STOX2 to increase cell proliferation and metastasis in hydatidiform moles via ERK, AKT, and P38 signaling pathways.
Mdivi-1 alleviates cardiac fibrosis post myocardial infarction at infarcted border zone, possibly via inhibition of Drp1-Activated mitochondrial fission and oxidative stress.
N-methyl-D-aspartic acid increases tight junction protein destruction in brain endothelial cell via caveolin-1-associated ERK1/2 signaling.
Gene knockdown of CCR3 reduces eosinophilic inflammation and the Th2 immune response by inhibiting the PI3K/AKT pathway in allergic rhinitis mice.
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex.
Integrative analysis of DNA methylation and gene expression reveals key molecular signatures in acute myocardial infarction.
The "LLQY" Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles.
Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells.
Antibody-drug conjugates targeting CD248 inhibits liver fibrosis through specific killing on myofibroblasts.
A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling.
CRISPR-iPAS: a novel dCAS13-based method for alternative polyadenylation interference.
Excess iodide-induced reactive oxygen species elicit iodide efflux via β-tubulin-associated ClC-3 in thyrocytes.
Long noncoding RNA Lnc-DIF inhibits bone formation by sequestering miR-489-3p.
Cholesterol promotes EGFR-TKIs resistance in NSCLC by inducing EGFR/Src/Erk/SP1 signaling-mediated ERRα re-expression.
USP49-Mediated Histone H2B Deubiquitination Regulates HCT116 Cell Proliferation through MDM2-p53 Axis.
Hsa_circ_0001666 promotes non-small cell lung cancer migration and invasion through miR-1184/miR-548I/AGO1 axis.
Risk subtyping and prognostic assessment of prostate cancer based on consensus genes.
The role of α5-nicotinic acetylcholine receptor/NLRP3 signaling pathway in lung adenocarcinoma cell proliferation and migration.
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Protective role of mRNA demethylase FTO on axon guidance molecules of nigro-striatal projection system in manganese-induced parkinsonism.
Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.
Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.
LMBR1L regulates the proliferation and migration of endothelial cells through Norrin/β-catenin signaling.
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer.
Inhibition of microRNA-448 suppresses CD4(+) T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus.
CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT.
LncRNA RP5-998N21.4 promotes immune defense through upregulation of IFIT2 and IFIT3 in schizophrenia.
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence.
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Inclisiran inhibits oxidized low-density lipoprotein-induced foam cell formation in Raw264.7 macrophages via activating the PPARγ pathway.
The nuclear receptor REV-ERBα regulates CYP2E1 expression and acetaminophen hepatotoxicity.
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Novel insights for PI3KC3 in mediating lipid accumulation in yellow catfish Pelteobagrus fulvidraco.
In Vivo and In Vitro Fibroblasts' Behavior and Capsular Formation in Correlation with Smooth and Textured Silicone Surfaces.
TRIM32 Inhibition Attenuates Apoptosis, Oxidative Stress, and Inflammatory Injury in Podocytes Induced by High Glucose by Modulating the Akt/GSK-3β/Nrf2 Pathway.
Histone H3K9 methyltransferase SETDB1 augments invadopodia formation to promote tumor metastasis.
LncRNA small nucleolar RNA host gene 16 reduces sepsis-induced myocardial damage by regulating miR-421/suppressor of cytokine signaling 5 axis.
Restraint of FAM60A has a cancer-inhibiting role in pancreatic carcinoma via the effects on the Akt/GSK-3β/β-catenin signaling pathway.
Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.
Protective effect of C-phycocyanin and apo-phycocyanin subunit on programmed necrosis of GC-1 spg cells induced by H(2) O(2).
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
MicroRNA-139-5p negatively regulates NME1 expression in hepatocellular carcinoma cells.
Microtubule depolymerization limits porcine betacoronavirus PHEV replication.
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice.
Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis.
Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion mice.
Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival.
The crucial role of thioredoxin interacting protein in the liver insulin resistance induced by di (2-ethylhexyl) phthalates.
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.
Identity of MMP1 and its effects on tumor progression in head and neck squamous cell carcinoma.
α(1) -Adrenoceptors activate the NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation.
Exercise training improves cardiac function and regulates myocardial mitophagy differently in ischaemic and pressure-overload heart failure mice.
SIRT1 alleviates IL-1β induced nucleus pulposus cells pyroptosis via mitophagy in intervertebral disc degeneration.
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
A novel frameshift variant in the TSPAN12 gene causes autosomal dominant FEVR.
Interleukin-20 is involved in dry eye disease and is a potential therapeutic target.
A Single Amino Acid Substitution in RFC4 Leads to Endoduplication and Compromised Resistance to DNA Damage in Arabidopsis thaliana.
Suppression of axonal attractant netrin-1 injured dopaminergic neuronal and motor function of mice during manganese overexposure.
A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency.
Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ.
Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis.
The Molecular Mechanism of Long Non-Coding RNA MALAT1-Mediated Regulation of Chondrocyte Pyroptosis in Ankylosing Spondylitis.
G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation.
Postnatal Cytomegalovirus Infection May Increase the Susceptibility of Tuberous Sclerosis Complex to Autism Spectrum Disorders.
DDX5/METTL3-METTL14/YTHDF2 Axis Regulates Replication of Influenza A Virus.
GALNT12 is associated with the malignancy of glioma and promotes glioblastoma multiforme in vitro by activating Akt signaling.
CaMKII and Kalirin, a Rac1-GEF, regulate Akt phosphorylation involved in contraction-induced glucose uptake in skeletal muscle cells.
The Expression and Role Analysis of Methylation-Regulated Differentially Expressed Gene UBE2C in Pan-Cancer, Especially for HGSOC.
CRISPR/Cas13 effectors have differing extents of off-target effects that limit their utility in eukaryotic cells.
Alu RNA induces NLRP3 expression through TLR7 activation in α-1-antitrypsin-deficient macrophages.
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.
Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells.
Structural characterization of a dimerization interface in the CD28 transmembrane domain.
Perfluorooctane sulfonate induces mitochondrial calcium overload and early hepatic insulin resistance via autophagy/detyrosinated alpha-tubulin-regulated IP3R2-VDAC1-MICU1 interaction.
Inhibition of Nicotinamide adenine dinucleotide phosphate oxidase 4 attenuates cell apoptosis and oxidative stress in a rat model of polycystic ovary syndrome through the activation of Nrf-2/HO-1 signaling pathway.
The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM(2.5) exposure-induced pulmonary fibrosis of mice.
Ambient particulate matter exposure plus a high-fat diet exacerbate renal injury by activating the NLRP3 inflammasome and TGF-β1/Smad2 signaling pathway in mice.
GM130 protects against blood-brain barrier disruption and brain injury after intracerebral hemorrhage by regulating autophagy formation.
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice.
Comparative and mechanistic study of pharmacodynamic difference in anti-breast cancer activity between water and liquor extracts of Xiaojin Pills.
p38α Deficiency in T Cells Ameliorates Diet-Induced Obesity, Insulin Resistance, and Adipose Tissue Senescence.
A signature of circadian rhythm genes in driving anaplastic thyroid carcinoma malignant progression.
Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
PPARγ Dysfunction in the Medial Prefrontal Cortex Mediates High-Fat Diet-Induced Depression.
NLRP3 inflammasome triggers interleukin-37 release from human monocytes.
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain.
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.
The α5-nAChR/PD-L1 axis facilitates lung adenocarcinoma cell migration and invasion.
Rapid synthesis of 'yolk-shell'-like nanosystem for MR molecular and chemo-radio sensitization.
Molybdenum and cadmium co-exposure induces endoplasmic reticulum stress-mediated apoptosis by Th1 polarization in Shaoxing duck (Anas platyrhyncha) spleens.
Genome-wide transcriptional profiling and functional analysis reveal miR-330-MAPK15 axis involving in cellular responses to deoxynivalenol exposure.
Melatonin inhibits osteoclastogenesis via RANKL/OPG suppression mediated by Rev-Erbα in osteoblasts.
A racemosin B derivative, C25, suppresses breast cancer growth via lysosomal membrane permeabilization and inhibition of autophagic flux.
The BDNF-TrkB signaling pathway in the rostral anterior cingulate cortex is involved in the development of pain aversion in rats with bone cancer via NR2B and ERK-CREB signaling.
Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy.
Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.
Role of TRPA1/TRPV1 in acute ozone exposure induced murine model of airway inflammation and bronchial hyperresponsiveness.
ER stress-related protein, CHOP, may serve as a biomarker of mechanical asphyxia: a primary study.
MicroRNA-mediated high expression of PDIA3 was correlated with poor prognosis of patients with LUAD.
GRSF1 predicts an unfavorable prognosis and promotes tumorigenesis in lung adenocarcinoma based on bioinformatics analysis and in vitro validation.
Maternal High-Fat Diet Reduces Type-2 Neural Stem Cells and Promotes Premature Neuronal Differentiation during Early Postnatal Development.
Cyclosporin A up-regulated thromboxane A(2) receptor through activation of MAPK and NF-κB pathways in rat mesenteric artery.
Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice.
Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARγ pathway.
Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.
Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice.
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
Endoplasmic reticulum stress contributes to cisplatin-induced chronic kidney disease via the PERK-PKCδ pathway.
MiR-152-5p suppresses osteogenic differentiation of mandible mesenchymal stem cells by regulating ATG14-mediated autophagy.
miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure.
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma.
Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer.
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology.
ACSL4 promotes colorectal cancer and is a potential therapeutic target of emodin.
Inhibition of TWEAK/Tnfrsf12a axis protects against acute liver failure by suppressing RIPK1-dependent apoptosis.
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Quantitative Proteome Analysis Reveals Melissa officinalis Extract Targets Mitochondrial Respiration in Colon Cancer Cells.
SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway.
Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity.
lncRNA SNHG1 regulates odontogenic differentiation of human dental pulp stem cells via miR-328-3p/Wnt/β-catenin pathway.
Procyanidin B2 Alleviates Heat-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
Metformin protects against pericyte apoptosis and promotes neurogenesis through suppressing JNK p38 MAPK signalling activation in ischemia/reperfusion injury.
A novel nitidine chloride nanoparticle overcomes the stemness of CD133(+)EPCAM(+) Huh7 hepatocellular carcinoma cells for liver cancer therapy.
The Capillary Morphogenesis Gene 2 Triggers the Intracellular Hallmarks of Collagen VI-Related Muscular Dystrophy.
The miR-199a-5p/PD-L1 axis regulates cell proliferation, migration and invasion in follicular thyroid carcinoma.
Selective sphingosine-1-phosphate receptor 1 modulator attenuates blood-brain barrier disruption following traumatic brain injury by inhibiting vesicular transcytosis.
Cytokine receptor gp130 promotes postnatal proliferation of cardiomyocytes required for the normal functional development of the heart.
Early-life exposure to bisphenol A induces dysregulation of lipid homeostasis by the upregulation of SCD1 in male mice.
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Genomic polymorphisms at the crhr2 locus improve feed conversion efficiency through alleviation of hypothalamus-pituitary-interrenal axis activity in gibel carp (Carassius gibelio).
MELAS-associated m.5541C>T mutation caused instability of mitochondrial tRNA(Trp) and remarkable mitochondrial dysfunction.
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
African swine fever virus cysteine protease pS273R inhibits pyroptosis by noncanonically cleaving gasdermin D.
G-alpha interacting protein interacting protein, C terminus 1 regulates epileptogenesis by increasing the expression of metabotropic glutamate receptor 7.
LOXL1-AS1 communicating with TIAR modulates vasculogenic mimicry in glioma via regulation of the miR-374b-5p/MMP14 axis.
miR‑30a‑5p induces the adipogenic differentiation of bone marrow mesenchymal stem cells by targeting FAM13A/Wnt/β‑catenin signaling in aplastic anemia.
The Apolipoprotein C1 is involved in breast cancer progression via EMT and MAPK/JNK pathway.
Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells.
Cyclic helix B peptide promotes random-pattern skin flap survival via TFE3-mediated enhancement of autophagy and reduction of ROS levels.
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats.
Irisin lowers blood pressure in Zucker diabetic rats by regulating the functions of renal angiotensin II type 1 receptor via the inhibition of the NF-κB signaling pathway.
Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway.
The role of KLF4 in melanogenesis and homeostasis in sheep melanocytes.
Fe(III)-Shikonin Supramolecular Nanomedicine for Combined Therapy of Tumor via Ferroptosis and Necroptosis.
Baicalin ameliorates APEC-induced intestinal injury in chicks by inhibiting the PI3K/AKT-mediated NF-κB signaling pathway.
Quxie Capsule Alleviates Colitis-associated Colorectal Cancer Through Modulating the Gut Microbiota and Suppressing A. fumigatus-induced Aerobic Glycolysis.
Combined Effects of Tanshinone IIA and an Autophagy Inhibitor on the Apoptosis of Leukemia Cells via p53, Apoptosis-Related Proteins and Oxidative Stress Pathways.
Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis.
REV-ERBs negatively regulate mineralization of the cementoblasts.
Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis.
Intermittent Fasting Improves High-Fat Diet-Induced Obesity Cardiomyopathy via Alleviating Lipid Deposition and Apoptosis and Decreasing m6A Methylation in the Heart.
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Lycium barbarum polysaccharides attenuates high glucose-induced diabetic retinal angiogenesis by rescuing the expression of miR-15a-5p in RF/6A cells.
Kampo formulas alleviate aging-related emotional disturbances and neuroinflammation in male senescence-accelerated mouse prone 8 mice.
DNAJC10 correlates with tumor immune characteristics and predicts the prognosis of glioma patients.
iTRAQ-Based Proteomics Analysis of Human Cytomegalovirus Latency and Reactivation in T98G Cells.
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Upregulation of CENPM facilitates lung adenocarcinoma progression via PI3K/AKT/mTOR signaling pathway.
IKKε protects against starvation-induced NLRP3 inflammasome and pyroptosis in H9c2 cells by alleviating mitochondrial injury.
BMP7 Functions to Regulate Proliferation of Dermal Papilla Cells in Hu Sheep.
Single-Base Resolution Mapping Reveals Distinct 5-Formylcytidine in Saccharomyces cerevisiae mRNAs.
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease.
Bisphenol-A exposure leads to neurotoxicity through upregulating the expression of histone deacetylase 2 in vivo and in vitro.
Type-III interferon stimulated gene TRIM31 mutation in an HBV patient blocks its ability in promoting HBx degradation.
Regioselective hydroxylation of carbendazim by mammalian cytochrome P450: A combined experimental and computational study.
The role of polypeptide PDTLN1 in suppression of PI3K/AKT signaling causes cardiogenetic disorders in vitro and in vivo.
Synthesis and structure-activity relationship study of new biaryl amide derivatives and their inhibitory effects against hepatitis C virus.
Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain.
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Short-term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy.
Insight into Shenqi Jiangtang Granule on the improved insulin sensitivity by integrating in silico and in vivo approaches.
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
miR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy.
Neurokinin-1 receptor promotes non-small cell lung cancer progression through transactivation of EGFR.
The Role of RAD6B and PEDF in Retinal Degeneration.
Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection.
Reassessment of the Proteomic Composition and Function of Extracellular Vesicles in the Seminal Plasma.
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
Novel variant in BRAT1 with the lethal neonatal rigidity and multifocal seizure syndrome.
Extracellular domain of semaphorin 5A serves a tumor‑suppressing role by activating interferon signaling pathways in lung adenocarcinoma cells.
The Role of Ferroptosis Signature in Overall Survival and Chemotherapy of Pancreatic Adenocarcinoma.
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
MiR-195 promotes pancreatic β-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.
Tumor necrosis factor α upregulates the bile acid efflux transporter OATP3A1 via multiple signaling pathways in cholestasis.
RNA-binding protein RBM28 can translocate from the nucleolus to the nucleoplasm to inhibit the transcriptional activity of p53.
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Extracellular matrix stiffness controls VEGF(165) secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis.
Immune-related gene expression in skin, inflamed and keloid tissue from patients with keloids.
Altered transsulfuration pathway enzymes and redox homeostasis in inherited retinal degenerative diseases.
PI3K/Akt Signaling Pathway Ameliorates Oxidative Stress-Induced Apoptosis upon Manganese Exposure in PC12 Cells.
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.
Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice.
Bone marrow mesenchymal stem cells-derived exosomal microRNA-124-3p attenuates hypoxic-ischemic brain damage through depressing tumor necrosis factor receptor associated factor 6 in newborn rats.
tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).
Protective effects of agrimonolide on hypoxia-induced H9c2 cell injury by maintaining mitochondrial homeostasis.
Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.
Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis.
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Resveratrol attenuates inflammation and apoptosis through alleviating endoplasmic reticulum stress via Akt/mTOR pathway in fungus-induced allergic airways inflammation.
Resveratrol regulates intestinal barrier function in cyclophosphamide-induced immunosuppressed mice.
Phycocyanin inhibits Helicobacter pylori-induced hyper-proliferation in AGS cells via activation of the ROS/MAPK signaling pathway.
CPNE1 is a potential prognostic biomarker, associated with immune infiltrates and promotes progression of hepatocellular carcinoma.
Therapeutic effect of adipose stromal vascular fraction spheroids for partial bladder outlet obstruction induced underactive bladder.
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Treatment of bladder cancer by geoinspired synthetic chrysotile nanocarrier-delivered circPRMT5 siRNA.
CTRP3 alleviates cardiac ischemia/reperfusion injury via LAMP1/JIP2/JNK signaling pathway.
Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound.
Deregulated expression and subcellular localization of CPSF6, a circRNA-binding protein, promote malignant development of esophageal squamous cell carcinoma.
Tamoxifen Exerts Anticancer Effects on Pituitary Adenoma Progression via Inducing Cell Apoptosis and Inhibiting Cell Migration.
Dietary selenium sources differentially regulate selenium concentration, mRNA and protein expression of representative selenoproteins in various tissues of yellow catfish Pelteobagrus fulvidraco.
TJ-M2010-5, A self-developed MyD88 inhibitor, attenuates liver fibrosis by inhibiting the NF-κB pathway.
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.
Gata3 Silencing Is Involved in Neuronal Differentiation and Its Abnormal Expression Impedes Neural Activity in Adult Retinal Neurocytes.
Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.
Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner.
Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer.
Overexpressed integrin alpha 2 inhibits the activation of the transforming growth factor β pathway in pancreatic cancer via the TFCP2-SMAD2 axis.
Curcumin alleviates hepatic steatosis by improving mitochondrial function in postnatal overfed rats and fatty L02 cells through the SIRT3 pathway.
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Blocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization.
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway.
METTL3-m(6)A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Nanog mediated by FAO/ACLY signaling induces cellular dormancy in colorectal cancer cells.
Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice.
Integrated single-cell multiomics analysis reveals novel candidate markers for prognosis in human pancreatic ductal adenocarcinoma.
Mitochondria-Dependent Oxidative Stress Mediates ZnO Nanoparticle (ZnO NP)-Induced Mitophagy and Lipotoxicity in Freshwater Teleost Fish.
A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins.
Chicoric Acid Prevents Neuroinflammation and Neurodegeneration in a Mouse Parkinson's Disease Model: Immune Response and Transcriptome Profile of the Spleen and Colon.
Design, Synthesis, and Biological Evaluation of 2-((4-Bisarylmethyl-piperazin-1-yl)methyl)benzonitrile Derivatives as HCV Entry Inhibitors.
RNA-seq Analysis Reveals Potential Molecular Mechanisms of ZNF580/ZFP580 Promoting Neuronal Survival and Inhibiting Apoptosis after Hypoxic-ischemic Brain damage.
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study.
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).
Cytokine Profile From the Ligamentum Flavum in Patients with Ossification of the Posterior Longitudinal Ligament in the Cervical Spine.
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Tetrahydroxy stilbene glycoside attenuates endothelial cell premature senescence induced by H(2)O(2) through the microRNA-34a/SIRT1 pathway.
Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.
miR-550a-5p promotes the proliferation and migration of hepatocellular carcinoma by targeting GNE via the Wnt/β-catenin signaling pathway.
DNA2 mutation causing multisystemic disorder with impaired mitochondrial DNA maintenance.
Qushi Huayu decoction attenuated hepatic lipid accumulation via JAK2/STAT3/CPT-1A-related fatty acid β-oxidation in mice with non-alcoholic steatohepatitis.
Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.
Nanoparticle endothelial delivery of PGC-1α attenuates hypoxia-induced pulmonary hypertension by attenuating EndoMT-caused vascular wall remodeling.
CCK regulates osteogenic differentiation through TNFα/NF-κB in peri-implantitis.
Mahonia Alkaloids (MA) Ameliorate Depression Induced Gap Junction Dysfunction by miR-205/Cx43 Axis.
HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks.
Ethanolic extract of root from Arctium lappa L ameliorates obesity and hepatic steatosis in rats by regulating the AMPK/ACC/CPT-1 pathway.
ITGA2 induces STING expression in pancreatic cancer by inducing DNMT1 degradation.
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Involvement of LARP7 in Activation of SIRT1 to Inhibit NF-κB Signaling Protects Microglia from Acrylamide-Induced Neuroinflammation.
circRNA-MSR regulates the expression of FBXO21 to inhibit chondrocyte autophagy by targeting miR-761 in osteoarthritis.
Cyclophilin A binds to AKT1 and facilitates the tumorigenicity of Epstein-Barr virus by mediating the activation of AKT/mTOR/NF-κB positive feedback loop.
A novel IFNbeta-induced long non-coding RNA ZAP-IT1 interrupts Zika virus replication in A549 cells.
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
miR-1275 Inhibits Human Omental Adipose-Derived Stem Cells Differentiation Toward the Beige Phenotype via PRDM16.
Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy.
Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation.
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Salivary non-apoptotic tumoral microvesicles: A potential progressive marker in oral cancer patients.
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Glucocorticoid Receptor Contributes to Electroacupuncture-Induced Analgesia by Inhibiting Nav1.7 Expression in Rats With Inflammatory Pain Induced by Complete Freund's Adjuvant.
Therapeutic effects of JLX001 on neuronal necroptosis after cerebral ischemia-reperfusion in rats.
Inhibition of protein disulfide isomerase with PACMA-31 regulates monocyte tissue factor through transcriptional and posttranscriptional mechanisms.
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
Study on the correlation of high expression level of HuD with seborrheic keratosis and skin aging.
Spermidine Alleviates Intrauterine Hypoxia-Induced Offspring Newborn Myocardial Mitochondrial Damage in Rats by Inhibiting Oxidative Stress and Regulating Mitochondrial Quality Control.
Putative targeting by BX795 causes decrease in protein kinase C protein levels and inhibition of HSV1 infection.
Necrosulfonamide ameliorates intestinal inflammation via inhibiting GSDMD-medicated pyroptosis and MLKL-mediated necroptosis.
Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction.
Polysaccharide ORP-1 isolated from Oudemansiella raphanipes ameliorates age-associated intestinal epithelial barrier dysfunction in Caco-2 cells monolayer.
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Hepatic inhibitors expression profiling of venom-challenged Sinonatrix annularis and antidotal activities.
Notum leads to potential pro-survival of OSCC through crosstalk between Shh and Wnt/β-catenin signaling via p-GSK3β.
Extracellular trap can be trained as a memory response.
Prokineticin 2 promotes macrophages-mediated antibacterial host defense against bacterial pneumonia.
Candida tropicalis induces NLRP3 inflammasome activation via glycogen metabolism-dependent glycolysis and JAK-STAT1 signaling pathway in myeloid-derived suppressor cells to promote colorectal carcinogenesis.
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
MAC mediates mammary duct epithelial cell injury in plasma cell mastitis and granulomatous mastitis.
SPRY4 promotes adipogenic differentiation of human mesenchymal stem cells through the MEK-ERK1/2 signaling pathway.
Bioinformatics analysis to obtain critical genes regulated in subcutaneous adipose tissue after bariatric surgery.
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Mdivi-1 improves postoperative neurocognitive disorders in aged rats undergoing splenectomy by inhibiting dynamin-related protein-1.
Heat shock protein 40 of Streptococcus pneumoniae induces immune response of human dendritic cells via TLR4-dependent p38 MAPK and JNK signaling pathways.
Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation.
Molecular profiling identifies distinct subtypes across TP53 mutant tumors.
Intestinal Stem Cells Damaged by Deoxycholic Acid via AHR Pathway Contributes to Mucosal Barrier Dysfunction in High-Fat Feeding Mice.
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Pan-cancer analysis of the prognostic and immunological role of PAQR4.
Opuntia dillenii Haw. Polysaccharide Promotes Cholesterol Efflux in THP-1-Derived Foam Cells via the PPARγ-LXRα Signaling Pathway.
Role of Epidermal Growth Factor Receptor-Specific CAR-T Cells in the Suppression of Esophageal Squamous Cell Carcinoma.
Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway.
SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing.
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Dendritic lipopeptide liposomes decorated with dual-targeted proteins.
Synthesis and anticancer activity of novel histone deacetylase inhibitors that inhibit autophagy and induce apoptosis.
Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model.
A high efficient FVIII variant corrects bleeding in hemophilia A mouse model.
Baicalin regulates TLR4/IκBα/NFκB signaling pathway to alleviate inflammation in Doxorubicin related cardiotoxicity.
Construction and validation of a prognostic model for osteosarcoma patients based on autophagy-related genes.
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma.
Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviors.
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
A novel glycosylation-related gene signature predicts survival in patients with lung adenocarcinoma.
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
CPSF4 promotes tumor-initiating phenotype by enhancing VEGF/NRP2/TAZ signaling in lung cancer.
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
Curcumol inhibits EMCV replication by activating CH25H and inhibiting the formation of ROs.
Peroxiredoxin 4 secreted by cumulus cells ameliorates the maturation of oocytes in vitro.
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells.
Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets.
Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation.
Effect of Biodentine on Odonto/Osteogenic Differentiation of Human Dental Pulp Stem Cells.
Ruthenium red attenuates acute pancreatitis by inhibiting MCU and improving mitochondrial function.
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
A lipid-polymer hybrid nanoparticle (LPN)-loaded dissolving microneedle patch for promoting hair regrowth by transdermal miR-218 delivery.
Distribution and characterization of extrachromosomal circular DNA in colorectal cancer.
CD59-Regulated Ras Compartmentalization Orchestrates Antitumor T-cell Immunity.
Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance.
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Verteporfin inhibits the dedifferentiation of tubular epithelial cells via TGF-β1/Smad pathway but induces podocyte loss in diabetic nephropathy.
Complementary protective effects of autophagy and oxidative response against graphene oxide toxicity in Caenorhabditis elegans.
Developing a Naïve Bayesian Classification Model with PI3Kγ structural features for virtual screening against PI3Kγ: Combining molecular docking and pharmacophore based on multiple PI3Kγ conformations.
Inhibition of BRD4 decreases fibrous scarring after ischemic stroke in rats by inhibiting the phosphorylation of Smad2/3.
Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes.
Microalgae oil from Schizochytrium sp. alleviates obesity and modulates gut microbiota in high-fat diet-fed mice.
FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells.
Effect of CTP-mediated PTEN on 5637 bladder cancer cells and the underlying molecular mechanism.
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
LPCAT1 functions as an oncogene in cervical cancer through mediating JAK2/STAT3 signaling.
Novel indole-guanidine hybrids as potential anticancer agents: Design, synthesis and biological evaluation.
Glyphosate-induced mitochondrial reactive oxygen species overproduction activates parkin-dependent mitophagy to inhibit testosterone synthesis in mouse leydig cells.
Structural and functional insights into CST tethering in Tetrahymena thermophila telomerase.
Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells.
Optimisation and characterization of α-D-glucan produced by Bacillus velezensis RSDM1 and evaluation of its protective effect on oxidative stress in Tetrahymena thermophila induced by H(2)O(2).
Soybean soluble polysaccharide prevents obesity in high-fat diet-induced rats via lipid metabolism regulation.
Gastrodin improves neuroinflammation-induced cognitive dysfunction in rats by regulating NLRP3 inflammasome.
FGF21 at physiological concentrations regulates vascular endothelial cell function through multiple pathways.
Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.
IL-18BP Improves Early Graft Function and Survival in Lewis-Brown Norway Rat Orthotopic Liver Transplantation Model.
METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma.
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.
LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis.
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Enzymatic hydrolysate of porphyra enhances the intestinal mucosal functions in obese mice.
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Farnesoid X receptor contributes to oleanolic acid-induced cholestatic liver injury in mice.
Electroacupuncture attenuates pulmonary vascular remodeling in a rat model of chronic obstructive pulmonary disease via the VEGF/PI3K/Akt pathway.
Electroacupuncture alleviates anxiety and modulates amygdala CRH/CRHR1 signaling in single prolonged stress mice.
FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells.
KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B.
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis.
DDX3X alleviates doxorubicin-induced cardiotoxicity by regulating Wnt/β-catenin signaling pathway in an in vitro model.
Extracellular HSP90α promotes cellular senescence by modulating TGF-β signaling in pulmonary fibrosis.
NEAT1 in bone marrow mesenchymal stem cell-derived extracellular vesicles promotes melanoma by inducing M2 macrophage polarization.
CDK12 activates MYC to repress miR-28-5p/EZH2 and amplifies tonic BCR signaling to promote the development of diffuse large B-cell lymphoma.
Interaction between gut microbiota dysbiosis and lung infection as gut-lung axis caused by Streptococcus suis in mouse model.
A novel 7‑hypoxia‑related long non‑coding RNA signature associated with prognosis and proliferation in melanoma.
Skeletal muscle MiR-210 expression is associated with mitochondrial function in peripheral artery disease patients.
Long non-coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR-326/PKM2 axis.
Protective role of Achyranthes bidentata polysaccharides against chondrocyte extracellular matrix degeneration through lncRNA GAS5 in osteoarthritis.
PVT1 promotes resistance to 5-FU in colon cancer via the miR-486-5p/CDK4 axis.
miR-let-7c-3p targeting on Egr-1 contributes to the committed differentiation of leukemia cells into monocyte/macrophages.
In vitro experimental study on the formation of microRNA-34a loaded exosomes and their inhibitory effect in oral squamous cell carcinoma.
High VHL Expression Reverses Warburg Phenotype and Enhances Immunogenicity in Kidney Tumor Cells.
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes.
Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
Zinc-doped Prussian blue nanoparticles for mutp53-carrying tumor ion interference and photothermal therapy.
α-Terthienyl induces prostate cancer cell death through inhibiting androgen receptor expression.
Dioscin alleviates Alzheimer's disease through regulating RAGE/NOX4 mediated oxidative stress and inflammation.
β-cryptoxanthin alleviates myocardial ischaemia/reperfusion injury by inhibiting NF-κB-mediated inflammatory signalling in rats.
Circulating Exosomes from Mice with LPS-Induced Bone Loss Inhibit Osteoblast Differentiation.
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation.
Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.
Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer.
A yeast-based system to study SARS-CoV-2 M (pro) structure and to identify nirmatrelvir resistant mutations.
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson's Disease Model.
Discovery of highly potent and selective CRBN-recruiting EGFR(L858R/T790M) degraders in vivo.
Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance.
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
RBM45 is an m(6)A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs.
Upregulation of Spinal miR-155-5p Contributes to Mechanical Hyperalgesia by Promoting Inflammatory Activation of Microglia in Bone Cancer Pain Rats.
Intestinal Klebsiella pneumoniae Contributes to Pneumonia by Synthesizing Glutamine in Multiple Myeloma.
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs.
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.
Enhancing Tumor Therapy of Fe(III)-Shikonin Supramolecular Nanomedicine via Triple Ferroptosis Amplification.
Alteration of E2F2 Expression in Governing Endothelial Cell Senescence.
Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway.
Role of dual specificity phosphatases (DUSPs) in melanoma cellular plasticity and drug resistance.
The mechanism on Prevotella melaninogenica promoting the inflammatory progression of oral lichen planus.
Plasma Proteomic Profiling Reveals the Regulatory Factors of Milk Protein Synthesis in Holstein Cows.
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy.
PGE(2) -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase.
SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity.
Matrine induces autophagy in human neuroblastoma cells via blocking the AKT-mTOR pathway.
A novel mutation located in the intermembrane space domain of AFG3L2 causes dominant optic atrophy through decreasing the stability of the encoded protein.
Tri-n-butyl phosphate delays tissue repair by dysregulating neutrophil function in zebrafish.
Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling.
Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats.
Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verification.
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
Characterization of Mesothelin Glycosylation in Pancreatic Cancer: Decreased Core Fucosylated Glycoforms in Pancreatic Cancer Patients' Sera.
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Overexpression of MLF1IP promotes colorectal cancer cell proliferation through BRCA1/AKT/p27 signaling pathway.
Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer.
Activation of microglial GPR109A alleviates thermal hyperalgesia in female lupus mice by suppressing IL-18 and glutamatergic synaptic activity.
Letrozole promotes the expression of integrin αvβ3 and HOXA10 in endometrium of endometriosis.
COP1 Acts as a Ubiquitin Ligase for PCDH9 Ubiquitination and Degradation in Human Glioma.
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
NLRP2 inhibits cell proliferation and migration by regulating EMT in lung adenocarcinoma cells.
Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma.
Inhibiting uptake activity of organic anion transporter 2 by bile acids.
C1q/tumor necrosis factor-related protein 9 protects cultured chondrocytes from IL-1β-induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis.
FAM83A has a pro-tumor function in ovarian cancer by affecting the Akt/Wnt/β-catenin pathway.
Hsa_circRNA_0017620 regulated cell progression of non-small-cell lung cancer via miR-520a-5p/KRT5 axis.
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway.
Phylogenetic convergence of phase separation and mitotic function in the disordered protein BuGZ.
Circadian rhythm modulates endochondral bone formation via MTR1/AMPKβ1/BMAL1 signaling axis.
DEC1 promotes progression of Helicobacter pylori-positive gastric cancer by regulating Akt/NF-κB pathway.
Apatinib inhibits tumour progression and promotes antitumour efficacy of cytotoxic drugs in oesophageal squamous cell carcinoma.
Apelin-13/APJ induces cardiomyocyte hypertrophy by activating the Pannexin-1/P2X7 axis and FAM134B-dependent reticulophagy.
Salidroside suppresses the activation of nasopharyngeal carcinoma cells via targeting miR-4262/GRP78 axis.
Glucagon-like peptide-1 receptor agonist attenuates diabetic neuropathic pain via inhibition of NOD-like receptor protein 3 inflammasome in brain microglia.
PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence.
Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy.
GALNT4 primes monocytes adhesion and transmigration by regulating O-Glycosylation of PSGL-1 in atherosclerosis.
PI3K inhibitor 3-MA promotes the antiproliferative activity of esomeprazole in gastric cancer cells by downregulating EGFR via the PI3K/FOXO3a pathway.
MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2.
Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9.
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2.
Fat mass and obesity associated (FTO)-mediated N6-methyladenosine modification of Krüppel-like factor 3 (KLF3) promotes osteosarcoma progression.
MEK1/2 inhibitor inhibits neointima formation by activating miR-126-3p/ C-X-C motif chemokine ligand 12 (CXCL12)/C-X-C motif chemokine receptor 4 (CXCR4) axis.
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Heat shock factor 2-binding protein promotes tumor progression via activation of MAPK signaling pathway in lung adenocarcinoma.
Long non-coding RNA NRAV enhances proliferation and invasion of hepatocellular carcinoma cells by modulating the Wnt/β-catenin signaling pathway.
Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy.
PLOD3 regulates the expression of YAP1 to affect the progression of non-small cell lung cancer via the PKCδ/CDK1/LIMD1 signaling pathway.
miR-21 antagonist alleviates colitis and angiogenesis via the PTEN/PI3K/AKT pathway in colitis mice induced by TNBS.
MPZ gene variant site in Chinese patients with Charcot-Marie-Tooth disease.
Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer.
Gadolinium-based contrast agent accelerates the migration of astrocyte via integrin αvβ3 signaling pathway.
Architecture of the human NALCN channelosome.
Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway.
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma.
M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation.
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease.
Male infertility-associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery.
ATP6AP2 knockdown in cardiomyocyte deteriorates heart function via compromising autophagic flux and NLRP3 inflammasome activation.
Effect of allisartan on blood pressure and left ventricular hypertrophy through Kv1.5 channels in hypertensive rats.
Structure-Based Discovery of MDM2/4 Dual Inhibitors that Exert Antitumor Activities against MDM4-Overexpressing Cancer Cells.
Mechanical stimulation promotes enthesis injury repair by mobilizing Prrx1(+) cells via ciliary TGF-β signaling.
Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages.
EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism.
IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis.
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
[Protective effect of Epothilone D against traumatic optic nerve injury in rats].
Relationship between Neuroprotective Effects and Structure of Procyanidins.
The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors.
Indole alkaloids of Alstonia scholaris (L.) R. Br. alleviated nonalcoholic fatty liver disease in mice fed with high-fat diet.
Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation.
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.
A Single Amino Acid Residue R144 of SNX16 Affects Its Ability to Inhibit the Replication of Influenza A Virus.
MFSD4A inhibits the malignant progression of nasopharyngeal carcinoma by targeting EPHA2.
Neurturin promotes tumor cell motility and angiogenesis in colorectal cancer.
CircSCAP interacts with SF3A3 to inhibit the malignance of non-small cell lung cancer by activating p53 signaling.
Rho kinase inhibition ameliorates vascular remodeling and blood pressure elevations in a rat model of apatinib-induced hypertension.
Identification of a heterozygous variant of ZP2 as a novel cause of empty follicle syndrome in humans and mice.
UBE2E3 regulates cellular senescence and osteogenic differentiation of BMSCs during aging.
Icaritin protects SH-SY5Y cells transfected with TDP-43 by alleviating mitochondrial damage and oxidative stress.
High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study.
NFIB promotes the migration and progression of kidney renal clear cell carcinoma by regulating PINK1 transcription.
Role of GDNF, GFRα1 and GFAP in a Bifidobacterium-Intervention Induced Mouse Model of Intestinal Neuronal Dysplasia.
GLIS Family Zinc Finger 1 was First Linked With Preaxial Polydactyly I in Humans by Stepwise Genetic Analysis.
Estrogen Attenuates Chronic Stress-Induced Cardiomyopathy by Adaptively Regulating Macrophage Polarizations via β(2)-Adrenergic Receptor Modulation.
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
SYMPK Is Required for Meiosis and Involved in Alternative Splicing in Male Germ Cells.
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
LncRNA NEAT1 Promotes Gastric Cancer Progression Through miR-17-5p/TGFβR2 Axis Up-Regulated Angiogenesis.
IRE1-mTOR-PERK Axis Coordinates Autophagy and ER Stress-Apoptosis Induced by P2X7-Mediated Ca(2+) Influx in Osteoarthritis.
NR2F1-AS1/miR-190a/PHLDB2 Induces the Epithelial-Mesenchymal Transformation Process in Gastric Cancer by Promoting Phosphorylation of AKT3.
GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis.
CircGNG4 Promotes the Progression of Prostate Cancer by Sponging miR-223 to Enhance EYA3/c-myc Expression.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
SMARCC1 Suppresses Tumor Progression by Inhibiting the PI3K/AKT Signaling Pathway in Prostate Cancer.
PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks.
Bhlhe40/Sirt1 Axis-Regulated Mitophagy Is Implicated in All-Trans Retinoic Acid-Induced Spina Bifida Aperta.
Tea Polyphenols Prevent Sepsis-Induced Lung Injury via Promoting Translocation of DJ-1 to Mitochondria.
Schwann Cell-Derived Exosomes Induce the Differentiation of Human Adipose-Derived Stem Cells Into Schwann Cells.
MCC Regulator of WNT Signaling Pathway (MCC) Is a Podocyte Essential Gene.
Sodium-Glucose Co-transporter-2 Inhibitor of Dapagliflozin Attenuates Myocardial Ischemia/Reperfusion Injury by Limiting NLRP3 Inflammasome Activation and Modulating Autophagy.
Establishment of a Dihydrofolate Reductase Gene Knock-In Zebrafish Strain to Aid Preliminary Analysis of Congenital Heart Disease Mechanisms.
Caspase-1 Inhibitor Reduces Pyroptosis Induced by Brain Death in Kidney.
Chromatin-Associated Protein Sugp2 Involved in mRNA Alternative Splicing During Mouse Spermatogenesis.
Isoproterenol-Induced Cardiomyopathy Recovery Intervention: Amlexanox and Forskolin Enhances the Resolution of Catecholamine Stress-Induced Maladaptive Myocardial Remodeling.
Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway.
Taurine Protects C2C12 Myoblasts From Impaired Cell Proliferation and Myotube Differentiation Under Cisplatin-Induced ROS Exposure.
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.
Inhibition of Peptidyl Arginine Deiminase 4-Dependent Neutrophil Extracellular Trap Formation Reduces Angiotensin II-Induced Abdominal Aortic Aneurysm Rupture in Mice.
Pilose Antler Peptide-3.2KD Ameliorates Adriamycin-Induced Myocardial Injury Through TGF-β/SMAD Signaling Pathway.
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Renal NKCC2 Is Dual Regulated by the Synergy of 20-HETE and High-Fat Diet in CYP4F2 Transgenic Mice.
Molecular mechanism of dihydropyrazine-induced cytotoxicity: the possibility of an independent pathway from the receptor for advanced glycation end products.
KCNN4 promotes the progression of lung adenocarcinoma by activating the AKT and ERK signaling pathways.
Contribution of Growth Arrest-Specific 5/miR-674 to the Hypothalamus Pituitary Adrenal Axis Regulation Effect by Electroacupuncture following Trauma.
Comparative proteome analysis of form-deprivation myopia in sclera with iTRAQ-based quantitative proteomics.
Analysis of Key Distinct Biological Characteristics of Human Placenta-Derived Mesenchymal Stromal Cells and Individual Heterogeneity Attributing to Donors.
Nucleolin Promotes Cisplatin Resistance in Cervical Cancer by the YB1-MDR1 Pathway.
Protective Role of 4-Octyl Itaconate in Murine LPS/D-GalN-Induced Acute Liver Failure via Inhibiting Inflammation, Oxidative Stress, and Apoptosis.
Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation.
Escin Sodium Improves the Prognosis of Acute Pancreatitis via Promoting Cell Apoptosis by Suppression of the ERK/STAT3 Signaling Pathway.
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury.
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity.
Paeoniflorin Protects against ANIT-Induced Cholestatic Liver Injury in Rats via the Activation of SIRT1-FXR Signaling Pathway.
GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation.
lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis.
Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene.
Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration.
TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38(-/-) Sepsis Mice.
High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.
ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling.
Tilianin Ameliorates Cognitive Dysfunction and Neuronal Damage in Rats with Vascular Dementia via p-CaMKII/ERK/CREB and ox-CaMKII-Dependent MAPK/NF-κB Pathways.
Follistatin-Like 1 Attenuation Suppresses Intervertebral Disc Degeneration in Mice through Interacting with TNF-α and Smad Signaling Pathway.
Electroacupuncture Inhibits Autophagy of Neuron Cells in Postherpetic Neuralgia by Increasing the Expression of miR-223-3p.
Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway.
Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy.
Glucagon-like Peptide-1 Improves Fatty Liver and Enhances Thermogenesis in Brown Adipose Tissue via Inhibiting BMP4-Related Signaling Pathway in High-Fat-Diet-Induced Obese Mice.
Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway.
FTZ Ameliorates Diabetic Cardiomyopathy by Inhibiting Inflammation and Cardiac Fibrosis in the Streptozotocin-Induced Model.
Pharmic Activation of PKG2 Alleviates Diabetes-Induced Osteoblast Dysfunction by Suppressing PLCβ1-Ca(2+)-Mediated Endoplasmic Reticulum Stress.
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway.
Shen Shuai II Recipe Attenuates Renal Interstitial Fibrosis by Improving Hypoxia via the IL-1β/c-Myc Pathway.
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
miR-381-3p Involves in Glioma Progression by Suppressing Tumor-Promoter Factor ANTXR1.
YQHX Alleviates H/R-Induced Cardiomyocyte Apoptosis by Downregulating miR-1.
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways.
ARHGAP11A Promotes the Malignant Progression of Gastric Cancer by Regulating the Stability of Actin Filaments through TPM1.
miR-19a-3p Promotes Tumor-Relevant Behaviors in Bladder Urothelial Carcinoma via Targeting THBS1.
Huanglian Jiedu Decoction Exerts Antipyretic Effect by Inhibiting MAPK Signaling Pathway.
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells.
PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosis.
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway.
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185.
SEC23A Inhibit Melanoma Metastatic through Secretory PF4 Cooperation with SPARC to Inhibit MAPK Signaling Pathway.
ACE2 Correlated With Immune Infiltration Serves As A Novel Prognostic Biomarker In Clear Cell Renal Cell Carcinoma: Implication For COVID-19.
Vagal Nerve Stimulation Protects Against Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis.
LINC00958 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of oesophageal squamous cell carcinoma cells.
Bioinformatics analysis for the role of CALR in human cancers.
Prognostic role of oxytocin receptor in colon adenocarcinoma.
Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species.
Expression of the ACE2 Virus Entry Protein in the Nervus Terminalis Reveals the Potential for an Alternative Route to Brain Infection in COVID-19.
Gut Microbial Metabolite Short-Chain Fatt Acids Partially Reverse Surgery and Anesthesia-Induced Behavior Deficits in C57BL/6J Mice.
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
High-Dose Dexmedetomidine Promotes Apoptosis in Fetal Rat Hippocampal Neurons.
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Aberrant Fluid Shear Stress Contributes to Articular Cartilage Pathogenesis via Epigenetic Regulation of ZBTB20 by H3K4me3.
Effects of UV Induced-Photoaging on the Hair Follicle Cycle of C57BL6/J Mice.
ILT4 in Colorectal Cancer Cells Induces Suppressive T Cell Contexture and Disease Progression.
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
The ALDOA Metabolism Pathway as a Potential Target for Regulation of Prostate Cancer Proliferation.
Store-Operated Calcium Channels Contribute to Remifentanil-Induced Postoperative Hyperalgesia via Phosphorylation of CaMKIIα in Rats.
Downregulation of TAF9B by miR-7-5p Inhibits the Progression of Osteosarcoma.
MicroRNA-302s Might Regulate ARL4C-Mediated Gastric Cancer Progression via p53 Signaling: Bioinformatics Analysis and Experiments Validation.
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes.
Prognostic Value and Biological Functions of RNA Binding Proteins in Stomach Adenocarcinoma.
Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study.
Hydrogen (H(2)) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway.
MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats.
Ulinastatin protects against acetaminophen-induced liver injury by alleviating ferroptosis via the SIRT1/NRF2/HO-1 pathway.
Nox2 contributes to reactive oxygen species-induced redox imbalance in cancer-induced bone pain.
Analysis of m6A-Related lncRNAs for Prognosis Value and Response to Immune Checkpoint Inhibitors Therapy in Hepatocellular Carcinoma.
Circ_0006174 Accelerates Colorectal Cancer Progression Through Regulating miR-138-5p/MACC1 Axis.
LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process.
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway.
RNA-binding Protein MBNL2 regulates Cancer Cell Metastasis through MiR-182-MBNL2-AKT Pathway.
BZW2/5MP1 acts as a promising target in hepatocellular carcinoma.
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p.
HnRNP-F promotes the proliferation of bladder cancer cells mediated by PI3K/AKT/FOXO1.
A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway.
Cordyceps cicadae Ameliorates Renal Hypertensive Injury and Fibrosis Through the Regulation of SIRT1-Mediated Autophagy.
Shenkang Injection and Its Three Anthraquinones Ameliorates Renal Fibrosis by Simultaneous Targeting IƙB/NF-ƙB and Keap1/Nrf2 Signaling Pathways.
Cang-Ai Volatile Oil Ameliorates Depressive Behavior Induced by Chronic Stress Through IDO-Mediated Tryptophan Degradation Pathway.
HOTAIR Up-Regulation Activates NF-κB to Induce Immunoescape in Gliomas.
Melatonin Mitigates Oxazolone-Induced Colitis in Microbiota-Dependent Manner.
The Zebrafish Antiapoptotic Protein BIRC2 Promotes Edwardsiella piscicida Infection by Inhibiting Caspases and Accumulating p53 in a p53 Transcription-Dependent and -Independent Manner.
Herb-Drug Interaction Between Xiyanping Injection and Lopinavir/Ritonavir, Two Agents Used in COVID-19 Pharmacotherapy.
The Role of Estrogen Receptor α in Response to Longitudinal Bone Growth in ob/ob Mice.
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT.
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway.
PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma.
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis.
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3'UTR in Gastric Cancer Cells.
Pimpinellin Inhibits Collagen-induced Platelet Aggregation and Activation Through Inhibiting Granule Secretion and PI3K/Akt Pathway.
Clemastine Fumarate Attenuates Myocardial Ischemia Reperfusion Injury Through Inhibition of Mast Cell Degranulation.
Reynoutrin Improves Ischemic Heart Failure in Rats Via Targeting S100A1.
Neuropathic Injury-Induced Plasticity of GABAergic System in Peripheral Sensory Ganglia.
Function of Chick Subcutaneous Adipose Tissue During the Embryonic and Posthatch Period.
Salidroside Inhibits CCl(4)-Induced Liver Fibrosis in Mice by Reducing Activation and Migration of HSC Induced by Liver Sinusoidal Endothelial Cell-Derived Exosomal SphK1.
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
The Application of Functional Magnetic Resonance Imaging in Type 2 Diabetes Rats With Contrast-Induced Acute Kidney Injury and the Associated Innate Immune Response.
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Downregulated MicroRNA-327 Attenuates Oxidative Stress-Mediated Myocardial Ischemia Reperfusion Injury Through Regulating the FGF10/Akt/Nrf2 Signaling Pathway.
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
Synergic Neuroprotection Between Ligusticum Chuanxiong Hort and Borneol Against Ischemic Stroke by Neurogenesis via Modulating Reactive Astrogliosis and Maintaining the Blood-Brain Barrier.
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Maternal Nicotine Exposure Alters Hippocampal Microglia Polarization and Promotes Anti-inflammatory Signaling in Juvenile Offspring in Mice.
MicroLet-7b Regulates Neutrophil Function and Dampens Neutrophilic Inflammation by Suppressing the Canonical TLR4/NF-κB Pathway.
SIRT1 Deacetylates TET2 and Promotes Its Ubiquitination Degradation to Achieve Neuroprotection Against Parkinson's Disease.
The Arachidonic Acid Metabolism Mechanism Based on UPLC-MS/MS Metabolomics in Recurrent Spontaneous Abortion Rats.
Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer.
4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response.
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis.
Identification of miRNA in Sheep Intramuscular Fat and the Role of miR-193a-5p in Proliferation and Differentiation of 3T3-L1.
Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock.
Proteomic Analysis of Red Ginseng on Prolonging the Life Span of Male Drosophila melanogaster.
Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in Rats.
Fuyuan Xingnao Decoction Promotes Angiogenesis Through the Rab1/AT1R Pathway in Diabetes Mellitus Complicated With Cerebral Infarction.
Precise Investigation of the Efficacy of Multicomponent Drugs Against Pneumonia Infected With Influenza Virus.
Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development.
3'untranslated regions (3'UTR) of Gelsolin mRNA displays anticancer effects in non-small cell lung cancer (NSCLC) cells.
Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma.
Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer.
βKlotho, a direct target of miR-206, contributes to the growth of hepatoblastoma through augmenting PI3K/Akt/mTOR signaling.
(125)I seed implantation brachytherapy for glottic carcinoma: an experimental and clinical study.
Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.
Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis.
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3.
Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.
Fiber scaffold bioartificial liver therapy relieves acute liver failure and extrahepatic organ injury in pigs.
Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.
Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion.
FAM21C Promotes Hepatocellular Carcinoma Invasion and Metastasis by Driving Actin Cytoskeleton Remodeling via Inhibiting Capping Ability of CAPZA1.
CD248(+) Cancer-Associated Fibroblasts: A Novel Prognostic and Therapeutic Target for Renal Cell Carcinoma.
Identification and Validation of TYMS as a Potential Biomarker for Risk of Metastasis Development in Hepatocellular Carcinoma.
Positive Reciprocal Feedback of lncRNA ZEB1-AS1 and HIF-1α Contributes to Hypoxia-Promoted Tumorigenesis and Metastasis of Pancreatic Cancer.
Novel Natural Inhibitors Targeting Enhancer of Zeste Homolog 2: A Comprehensive Structural Biology Research.
Integrin Alpha-2 as a Potential Prognostic and Predictive Biomarker for Patients With Lower-Grade Glioma.
CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
CK-3, A Novel Methsulfonyl Pyridine Derivative, Suppresses Hepatocellular Carcinoma Proliferation and Invasion by Blocking the PI3K/AKT/mTOR and MAPK/ERK Pathways.
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Hypoxia-Induced LncRNA-MIR210HG Promotes Cancer Progression By Inhibiting HIF-1α Degradation in Ovarian Cancer.
TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma.
Downregulation of ATXN3 Enhances the Sensitivity to AKT Inhibitors (Perifosine or MK-2206), but Decreases the Sensitivity to Chemotherapeutic Drugs (Etoposide or Cisplatin) in Neuroblastoma Cells.
AUF1 Promotes Proliferation and Invasion of Thyroid Cancer via Downregulation of ZBTB2 and Subsequent TRIM58.
Prognostic and Predictive Value of Immune-Related Gene Pair Signature in Primary Lower-Grade Glioma Patients.
DDX60 Is Associated With Glioma Malignancy and Serves as a Potential Immunotherapy Biomarker.
Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma.
Targeting Mutated p53 Dependency in Triple-Negative Breast Cancer Cells Through CDK7 Inhibition.
The LncRNA CASC11 Promotes Colorectal Cancer Cell Proliferation and Migration by Adsorbing miR-646 and miR-381-3p to Upregulate Their Target RAB11FIP2.
FOXP3 Inhibits the Metastasis of Breast Cancer by Downregulating the Expression of MTA1.
Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer.
Molecular and Clinical Characterization of UBE2S in Glioma as a Biomarker for Poor Prognosis and Resistance to Chemo-Radiotherapy.
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma.
MiR-338-5p Inhibits EGF-Induced EMT in Pancreatic Cancer Cells by Targeting EGFR/ERK Signaling.
The Human Cytomegalovirus US31 Gene Predicts Favorable Survival and Regulates the Tumor Microenvironment in Gastric Cancer.
STAM Prolongs Clear Cell Renal Cell Carcinoma Patients' Survival via Inhibiting Cell Growth and Invasion.
Canagliflozin Improves Liver Function in Rats by Upregulating Asparagine Synthetase.
Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway.
Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage.
Hyperoxia-induced S1P(1) signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia.
Melatonin and other indoles show antiviral activities against swine coronaviruses in vitro at pharmacological concentrations.
Secretions released from mesenchymal stem cells improve spermatogenesis restoration of cytotoxic treatment with busulfan in azoospermia mice.
Diurnal hepatic CYP3A11 contributes to chronotoxicity of the pyrrolizidine alkaloid retrorsine in mice.
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Long noncoding RNA HOTAIR functions as ceRNA to regulate MMP2 in paraquat induced lung epithelial-mesenchymal transition.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGA1.
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
Morinda citrifolia (Noni) Juice Suppresses A549 Human Lung Cancer Cells via Inhibiting AKT/Nuclear Factor-κ B Signaling Pathway.
Yes-associated protein regulates the hepatoprotective effect of vitamin D receptor activation through promoting adaptive bile duct remodeling in cholestatic mice.
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity.
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment.
Bone mesenchymal stem cells attenuate resiniferatoxin-induced neuralgia via inhibiting TRPA1-PKCδ-P38/MAPK-p-P65 pathway in mice.
Role of the SENP1-SIRT1 pathway in hyperoxia-induced alveolar epithelial cell injury.
Genetic association scan of 32 osteoarthritis susceptibility genes identified TP63 associated with an endemic osteoarthritis, Kashin-Beck disease.
Hsa_circ_0001021 regulates intestinal epithelial barrier function via sponging miR-224-5p in ulcerative colitis.
Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration.
[ANXA8 Regulates Proliferation of Human Non-Small Lung Cancer Cells A549 via EGFR-AKT-mTOR Signaling Pathway].
Dipeptidyl peptidase-4 (DPP4) inhibitor sitagliptin alleviates liver inflammation of diabetic mice by acting as a ROS scavenger and inhibiting the NFκB pathway.
Circβ-catenin promotes tumor growth and Warburg effect of gallbladder cancer by regulating STMN1 expression.
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
iTRAQ-based proteome analysis of porcine group A rotavirus-infected porcine IPEC-J2 intestinal epithelial cells.
The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe(-/-) Mice through Modulating Macrophage Functions.
LncRNA MEG3 inhibits the proliferation of neural stem cells after ischemic stroke via the miR-493-5P/MIF axis.
Penetration Cascade of Size Switchable Nanosystem in Desmoplastic Stroma for Improved Pancreatic Cancer Therapy.
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
The dysfunction of parvalbumin interneurons mediated by microglia contributes to cognitive impairment induced by lipopolysaccharide challenge.
Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer.
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma.
18β-Glycyrrhetinic acid inhibits IL-1β-induced inflammatory response in mouse chondrocytes and prevents osteoarthritic progression by activating Nrf2.
Melatonin as Immune Potentiator for Enhancing Subunit Vaccine Efficacy against Bovine Viral Diarrhea Virus.
LHX9, a p53-binding protein, inhibits the progression of glioma by suppressing glycolysis.
Salvianolic acid-B improves fat graft survival by promoting proliferation and adipogenesis.
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
Protective effects of dioscin against isoproterenol-induced cardiac hypertrophy via adjusting PKCε/ERK-mediated oxidative stress.
TRAIL produced by SAM-1-activated CD4(+) and CD8(+) subgroup T cells induces apoptosis in human tumor cells through upregulation of death receptors.
LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling.
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness.
N-Myc promotes angiogenesis and therapeutic resistance of prostate cancer by TEM8.
Gypenoside Inhibits Bovine Viral Diarrhea Virus Replication by Interfering with Viral Attachment and Internalization and Activating Apoptosis of Infected Cells.
Hsa_circ_0001361 facilitates the progress of lung adenocarcinoma cells via targeting miR-525-5p/VMA21 axis.
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
NRF2 deficiency sensitizes human keratinocytes to zinc oxide nanoparticles-induced autophagy and cytotoxicity.
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming.
CG223, a novel BET inhibitor, exerts TGF-β1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis.
A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury.
W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34.
Prednisolone induces osteocytes apoptosis by promoting Notum expression and inhibiting PI3K/AKT/GSK3β/β-catenin pathway.
Downregulation of fibronectin 1 attenuates ATRA-induced inhibition of cell migration and invasion in neuroblastoma cells.
Pgc-1α Promotes Phosphorylation, Inflammation, and Apoptosis in H9c2 Cells During the Early Stage of Lipopolysaccharide Induction.
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
CCL2 is a critical mechano-responsive mediator in crosstalk between osteoblasts and bone mesenchymal stromal cells.
The protective effect and potential mechanism of NRXN1 on learning and memory in ADHD rat models.
5-IP(7) is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
POSTN Promotes the Proliferation of Spermatogonial Cells by Activating the Wnt/β-Catenin Signaling Pathway.
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes.
Adiponectin regulates osteocytic MLO-Y4 cell apoptosis in a high-glucose environment through the AMPK/FoxO3a signaling pathway.
ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway.
Comprehensive analysis of differentially expressed genes reveals the promotive effects of UBE2T on colorectal cancer cell proliferation.
Gardnerella vaginalis induces NLRP3 inflammasome-mediated pyroptosis in macrophages and THP-1 monocytes.
Prophylactic treatment with BX795 blocks activation of AKT and its downstream targets to protect vaginal keratinocytes and vaginal epithelium from HSV-2 infection.
Exogenous extracellular matrix proteins decrease cardiac fibroblast activation in stiffening microenvironment through CAPG.
Study on the potential nephrotoxicity and mutagenicity of aristolochic acid IVa and its mechanism.
The polypeptide OP3-4 induced osteogenic differentiation of bone marrow mesenchymal stem cells via protein kinase B/glycogen synthase kinase 3β/β-catenin pathway and promoted mandibular defect bone regeneration.
Notum suppresses the osteogenic differentiation of periodontal ligament stem cells through the Wnt/Beta catenin signaling pathway.
Arsenic sulfide reverses cisplatin resistance in non-small cell lung cancer in vitro and in vivo through targeting PD-L1.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation.
Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD(+) to alleviate mitochondrial disease.
Dietary curcumin supplementation promotes browning and energy expenditure in postnatal overfed rats.
Reciprocal regulation between ER stress and autophagy in renal tubular fibrosis and apoptosis.
SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.
TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception.
Constructing a passive targeting and long retention therapeutic nanoplatform based on water-soluble, non-toxic and highly-stable core-shell poly(amino acid) nanocomplexes.
ZBTB38 suppresses prostate cancer cell proliferation and migration via directly promoting DKK1 expression.
DLX6-AS1 activated by H3K4me1 enhanced secondary cisplatin resistance of lung squamous cell carcinoma through modulating miR-181a-5p/miR-382-5p/CELF1 axis.
Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase.
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
Hepatic P38 Activation Modulates Systemic Metabolism Through Fgf21-Mediated Interorgan Communication.
Chromatin Accessibility and Transcriptomic Alterations in Murine Ovarian Granulosa Cells upon Deoxynivalenol Exposure.
Deficiency of ER Ca(2+) sensor STIM1 in AgRP neurons confers protection against dietary obesity.
Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling.
The Role of Nrf2 Transcription Factor and Sp1-Nrf2 Protein Complex in Glutamine Transporter SN1 Regulation in Mouse Cortical Astrocytes Exposed to Ammonia.
Non-stoichiometric cobalt sulfide nanodots enhance photothermal and chemodynamic therapies against solid tumor.
Regulation of survivin protein stability by USP35 is evolutionarily conserved.
Sulourea-coordinated Pd nanocubes for NIR-responsive photothermal/H(2)S therapy of cancer.
mTORC2 confers neuroprotection and potentiates immunity during virus infection.
An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.
Selenium Restores Synaptic Deficits by Modulating NMDA Receptors and Selenoprotein K in an Alzheimer's Disease Model.
Hydrogel loading functionalized PAMAM/shRNA complex for postsurgical glioblastoma treatment.
Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways.
Inclusion of a short hairpin RNA targeting BCL11A into a β-globin expressing vector allows concurrent synthesis of curative adult and fetal hemoglobin.
Long non-coding RNA SNHG16 regulates E2F1 expression by sponging miR-20a-5p and aggravating proliferative diabetic retinopathy.
LncRNA 4344 promotes NLRP3-related neuroinflammation and cognitive impairment by targeting miR-138-5p.
The relationship between liver pathological inflammation degree and pyroptosis in chronic hepatitis B patients.
Sulfuretin exerts diversified functions in the processing of amyloid precursor protein.
The m(6) A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.
Lactate anions participate in T cell cytokine production and function.
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.
P-element Induced WImpy protein-like RNA-mediated gene silencing 2 regulates tumor cell progression, apoptosis, and metastasis in oral squamous cell carcinoma.
Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway.
Effect of Interleukin-1β on Gene Expression Signatures in Schwann Cells Associated with Neuropathic Pain.
AMOTL2 restrains transforming growth factor-β1-induced proliferation and extracellular matrix deposition of airway smooth muscle cells via the down-regulation of YAP1 activation.
Autophagy coordinates chondrocyte development and early joint formation in zebrafish.
A luciferase-based approach for measuring HBGA blockade antibody titers against human norovirus.
G protein-coupled estrogen receptor in the rostral ventromedial medulla contributes to the chronification of postoperative pain.
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E(2) Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
Dynamic changes of activated AHR in microglia and astrocytes in the substantia nigra-striatum system in an MPTP-induced Parkinson's disease mouse model.
Proteomic analysis of the influence of CO(2) pneumoperitoneum in cervical cancer cells.
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Modified citrus pectin prevents isoproterenol-induced cardiac hypertrophy associated with p38 signalling and TLR4/JAK/STAT3 pathway.
Apatinib combined with Keytruda treatment induces apoptosis of gastric carcinoma cells through CES4/miR-616-5p/DUSP2 axis.
Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway.
CXCR4 promotes gefitinib resistance of Huh7 cells by activating the c-Met signaling pathway.
Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway.
An anaphase surveillance mechanism prevents micronuclei formation from frequent chromosome segregation errors.
LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis.
African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis.
Dietary Nano-ZnO Is Absorbed via Endocytosis and ZIP Pathways, Upregulates Lipogenesis, and Induces Lipotoxicity in the Intestine of Yellow Catfish.
Rotigotine-loaded microspheres exerts the antinociceptive effect via central dopaminergic system.
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.
Degradation of WTAP blocks antiviral responses by reducing the m(6) A levels of IRF3 and IFNAR1 mRNA.
Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression.
Local activation of α2 adrenergic receptors is required for vagus nerve stimulation induced motor cortical plasticity.
Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors.
KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.
Polyethylenimine-Poly(lactic-co-glycolic acid)(2) Nanoparticles Show an Innate Targeting Ability to the Submandibular Salivary Gland via the Muscarinic 3 Receptor.
Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
CircMYOF triggers progression and facilitates glycolysis via the VEGFA/PI3K/AKT axis by absorbing miR-4739 in pancreatic ductal adenocarcinoma.
Genome-wide map of N(6)-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis.
A novel endoplasmic stress mediator, Kelch domain containing 7B (KLHDC7B), increased Harakiri (HRK) in the SubAB-induced apoptosis signaling pathway.
Blue Light Activated Rapamycin for Optical Control of Protein Dimerization in Cells and Zebrafish Embryos.
Targeting Ferroptosis by Polydopamine Nanoparticles Protects Heart against Ischemia/Reperfusion Injury.
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation.
Ochratoxin A Induces Steatosis via PPARγ-CD36 Axis.
BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2.
Overexpression of miR-224-5p alleviates allergic rhinitis in mice via the TLR4/MyD88/NF-κB pathway.
Moderate-intensity exercise alleviates pyroptosis by promoting autophagy in osteoarthritis via the P2X7/AMPK/mTOR axis.
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Malignant transformation of human bronchial epithelial cells induced by benzo [a] pyrene suggests a negative feedback of TP53 to PPP1R13L via binding a possible enhancer element.
Lipoxin A4 inhibits ovalbumin-induced airway inflammation and airway remodeling in a mouse model of asthma.
Selenite induced breast cancer MCF7 cells apoptosis through endoplasmic reticulum stress and oxidative stress pathway.
Anti-glioblastoma effects of nanomicelle-curcumin plus erlotinib.
IDO1 as a new immune biomarker for diabetic nephropathy and its correlation with immune cell infiltration.
Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways.
Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.
Myeloid TBK1 Deficiency Induces Motor Deficits and Axon Degeneration Through Inflammatory Cell Infiltration.
Postnatal deletion of Bmal1 in mice protects against obstructive renal fibrosis via suppressing Gli2 transcription.
The Role of Autophagy in Murine Cytomegalovirus Hepatitis.
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Effect of Kangquan Recipe () on BAMBI Expression in Hypothalamic-Pituitary-Prostate in Rats with Benign Prostatic Hyperplasia.
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Berberine ameliorates the LPS-induced imbalance of osteogenic and adipogenic differentiation in rat bone marrow-derived mesenchymal stem cells.
Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF‑κB signaling.
Galectin‑3 facilitates the proliferation and migration of nasopharyngeal carcinoma cells via activation of the ERK1/2 and Akt signaling pathways, and is positively correlated with the inflammatory state of nasopharyngeal carcinoma.
Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway.
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
IRF2BP2 prevents ox-LDL-induced inflammation and EMT in endothelial cells via regulation of KLF2.
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
MicroRNA-365b-3p represses the proliferation and promotes the apoptosis of non-small cell lung cancer cells by targeting PPP5C.
Knockdown of CLN5 inhibits the tumorigenic properties of glioblastoma cells via the Akt/mTOR signaling pathway.
Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.
A Ran-binding protein facilitates nuclear import of human papillomavirus type 16.
Pannexin 1, a large-pore membrane channel, contributes to hypotonicity-induced ATP release in Schwann cells.
miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF.
Effects of saikosaponin-d on CYP3A4 in HepaRG cell and protein-ligand docking study.
Downregulation of long non-coding RNA LOC101928477 correlates with tumor progression by regulating the epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7.
Long non-coding RNA TP73-AS1 promotes pancreatic cancer growth and metastasis through miRNA-128-3p/GOLM1 axis.
Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis.
Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis.
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Integrated analysis of long non-coding RNAs (lncRNAs) and mRNA expression profiles identifies lncRNA PRKG1-AS1 playing important roles in skeletal muscle aging.
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients.
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.
Validation of the functions and prognostic values of synapse-associated proteins in lower-grade glioma.
Nuclear exosome HMGB3 secreted by nasopharyngeal carcinoma cells promotes tumour metastasis by inducing angiogenesis.
Effects of increasing intake of soybean oil on synthesis of testosterone in Leydig cells.
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation.
[Development and functional validation of a nano-delivery system of miR-16/polypeptide targeting ovarian cancer cells].
GSDMD contributes to host defence against Staphylococcus aureus skin infection by suppressing the Cxcl1-Cxcr2 axis.
The small-molecule protein ligand interface stabiliser E7820 induces differential cell line specific responses of integrin α2 expression.
Histone chaperone CAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies.
Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.
CD157 in bone marrow mesenchymal stem cells mediates mitochondrial production and transfer to improve neuronal apoptosis and functional recovery after spinal cord injury.
Long noncoding RNA LYPLAL1-AS1 regulates adipogenic differentiation of human mesenchymal stem cells by targeting desmoplakin and inhibiting the Wnt/β-catenin pathway.
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
CircRNA_30032 promotes renal fibrosis in UUO model mice via miRNA-96-5p/HBEGF/KRAS axis.
IFIT5 Negatively Regulates the Type I IFN Pathway by Disrupting TBK1-IKKε-IRF3 Signalosome and Degrading IRF3 and IKKε.
Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway.
Tak1 in the astrocytes of mediobasal hypothalamus regulates anxiety-like behavior in mice.
Curcumin combined with low-intensity ultrasound suppresses the growth of glioma cells via inhibition of the AKT pathway.
Stromal cell-derived factor-1/Exendin-4 cotherapy facilitates the proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells in vitro and promotes periodontal bone regeneration in vivo.
SREBP1 suppresses the differentiation and epithelial function of hiPSC-derived endothelial cells by inhibiting the microRNA199b-5p pathway.
miR-132 Regulates PTSD-like Behaviors in Rats Following Single-Prolonged Stress Through Fragile X-Related Protein 1.
Cordyceps acid alleviates lung cancer in nude mice.
Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling.
Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis.
Caveolae/rafts protect human cerebral microvascular endothelial cells from Streptococcus suis serotype 2 α-enolase-mediated injury.
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction.
RPL41 sensitizes retinoblastoma cells to chemotherapeutic drugs via ATF4 degradation.
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
MiR-205 Inhibits Sporadic Vestibular Schwannoma Cell Proliferation by Targeting Cyclin-Dependent Kinase 14.
Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver.
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing.
Effects of PI3K/AKT/mTOR pathway regulation of HIF-1α on Lanthanum-induced neurotoxicity in rats.
Exosomal miR-365a-5p derived from HUC-MSCs regulates osteogenesis in GIONFH through the Hippo signaling pathway.
The RNA-Binding Protein CELF2 Inhibits Ovarian Cancer Progression by Stabilizing FAM198B.
Cerebral Cavernous Malformation 1 Determines YAP/TAZ Signaling-Dependent Metastatic Hallmarks of Prostate Cancer Cells.
Sildenafil improves right ventricular remodelling in monocrotaline-induced rats by decreasing myocardial apoptosis and activating peroxisome proliferator-activated receptors.
PTEN deficiency facilitates the therapeutic vulnerability to proteasome inhibitor bortezomib in gallbladder cancer.
Construction of PD1/CD28 chimeric-switch receptor enhances anti-tumor ability of c-Met CAR-T in gastric cancer.
Selenite Inhibits Notch Signaling in Cells and Mice.
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation.
Dietary Marginal and Excess Selenium Increased Triglycerides Deposition, Induced Endoplasmic Reticulum Stress and Differentially Influenced Selenoproteins Expression in the Anterior and Middle Intestines of Yellow Catfish Pelteobagrus fulvidraco.
Inhibition of chikusetsusaponin IVa on inflammatory responses in RAW264.7 cell line via MAPK pathway.
Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.
A nuclear export sequence promotes CRM1-dependent targeting of the nucleoporin Nup214 to the nuclear pore complex.
Silencing long non-coding RNA MIAT ameliorates myocardial dysfunction induced by myocardial infarction via MIAT/miR-10a-5p/EGR2 axis.
Localization of the WD repeat-containing protein 5 to the Virion Assembly Compartment Facilitates Human Cytomegalovirus Assembly.
Long non-coding RNA LNC_000641 regulates pseudorabies virus replication.
RNAi-mediated silencing of Trichinella spiralis glutaminase results in reduced muscle larval infectivity.
A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating β-TrCP E3 Ubiquitin Ligase.
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase.
A Unique Anti-Cancer 3-Styrylchromone Suppresses Inflammatory Response via HMGB1-RAGE Signaling.
FGF1(ΔHBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirus.
SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis.
Structure of the catalytic core of the Integrator complex.
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model.
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Clock knockdown attenuated reactive oxygen species-mediated senescence of chondrocytes through restoring autophagic flux.
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
SOCS6 promotes radiosensitivity and decreases cancer cell stemness in esophageal squamous cell carcinoma by regulating c-Kit ubiquitylation.
Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.
Clock gene Bmal1 controls diurnal rhythms in expression and activity of intestinal carboxylesterase 1.
Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.
Jinfukang regulates integrin/Src pathway and anoikis mediating circulating lung cancer cells migration.
A robust platform for expansion and genome editing of primary human natural killer cells.
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation.
Alpinetin protects against hepatic ischemia/reperfusion injury in mice by inhibiting the NF-κB/MAPK signaling pathways.
Deciphering the synergistic network regulation of active components from SiNiSan against irritable bowel syndrome via a comprehensive strategy: Combined effects of synephrine, paeoniflorin and naringin.
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1.
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
ODAM promotes junctional epithelium-related gene expression via activation of WNT1 signaling pathway in an ameloblast-like cell line ALC.
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Acetylation-stabilized chloride intracellular channel 1 exerts a tumor-promoting effect on cervical cancer cells by activating NF-κB.
Targeted inhibition of calpain in mitochondria alleviates oxidative stress-induced myocardial injury.
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
Generation of A Stable GFP-reporter Zika Virus System for High-throughput Screening of Zika Virus Inhibitors.
A novel nonsense variant in MT-CO3 causes MELAS syndrome.
Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives.
Dihydroartemisinin prompts amplification of photodynamic therapy-induced reactive oxygen species to exhaust Na/H exchanger 1-mediated glioma cells invasion and migration.
Transforming growth factor-β1-induced podocyte injury is associated with increased microRNA-155 expression, enhanced inflammatory responses and MAPK pathway activation.
IGF2BP2 knockdown inhibits LPS-induced pyroptosis in BEAS-2B cells by targeting caspase 4, a crucial molecule of the non-canonical pyroptosis pathway.
MicroRNA-133a-3p suppresses malignant behavior of non-small cell lung cancer cells by negatively regulating ERBB2.
PCTP contributes to human platelet activation by enhancing dense granule secretion.
TGF-β1-activated cancer-associated fibroblasts promote breast cancer invasion, metastasis and epithelial-mesenchymal transition by autophagy or overexpression of FAP-α.
Shengxuening Extracted from Silkworm Excrement Mitigates Myelosuppression via SCF-Mediated JAK2/STAT3 Signaling.
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
COL5A1 Variants Cause Aortic Dissection by Activating TGF-β-Signaling Pathway.
Niclosamide ethanolamine ameliorates diabetes-related muscle wasting by inhibiting autophagy.
Expression of the ACE2 virus entry protein in the nervus terminalis reveals the potential for an alternative route to brain infection in COVID-19.
Expression of deubiquitinases in human gingiva and cultured human gingival fibroblasts.
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving.
CircMAPK1 promotes the proliferation and migration of vascular smooth muscle cells through miR-22-3p/ methyl-CpG binding protein 2 axis.
STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose.
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.
Melatonin Ameliorates the Toxicity Induced by Deoxynivalenol in Murine Ovary Granulosa Cells by Antioxidative and Anti-Inflammatory Effects.
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Long noncoding RNA LINC00284 facilitates cell proliferation in papillary thyroid cancer via impairing miR-3127-5p targeted E2F7 suppression.
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease.
Apple Polyphenol Extract Improves High-Fat Diet-Induced Hepatic Steatosis by Regulating Bile Acid Synthesis and Gut Microbiota in C57BL/6 Male Mice.
Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection.
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.
Mobile element insertions and associated structural variants in longitudinal breast cancer samples.
Human amnion-derived mesenchymal stem cells improved the reproductive function of age-related diminished ovarian reserve in mice through Ampk/FoxO3a signaling pathway.
DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury.
Hollow PtCo alloy nanospheres as a high-Z and oxygen generating nanozyme for radiotherapy enhancement in non-small cell lung cancer.
NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.
Chlorogenic Acid Promotes Osteogenic Differentiation of Human Dental Pulp Stem Cells Through Wnt Signaling.
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation.
Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.
Small extracellular ring domain is necessary for CD82/KAI1'anti-metastasis function.
PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.
Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.
Tryptanthrin exerts anti-breast cancer effects both in vitro and in vivo through modulating the inflammatory tumor microenvironment.
Mitochondrial DNA enables AIM2 inflammasome activation and hepatocyte pyroptosis in nonalcoholic fatty liver disease.
Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis.
Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2-STAT3 pathway.
Modeling Cone/Cone-Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina.
Lipopolysaccharide/D-galactosamine-induced acute liver injury could be attenuated by dopamine receptor agonist rotigotine via regulating NF-κB signaling pathway.
Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis.
MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer.
Low androgen status inhibits erectile function by increasing pyroptosis in rat corpus cavernosum.
Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation.
Apoptotic caspases suppress Mycobacterium bovis-induced IFN-β production in murine macrophage.
Knockdown of USP9X reverses cisplatin resistance by decreasing β-catenin expression in nasopharyngeal carcinoma cells.
MDM2 induces EMT via the B‑Raf signaling pathway through 14‑3‑3.
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
High-fat diet exacerbates lead-induced blood-brain barrier disruption by disrupting tight junction integrity.
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Biliary excretion of excess iron in mice requires hepatocyte iron import by Slc39a14.
The antiviral enzyme viperin inhibits cholesterol biosynthesis.
The stabilization of yes-associated protein by TGFβ-activated kinase 1 regulates the self-renewal and oncogenesis of gastric cancer stem cells.
MACF1 alleviates aging-related osteoporosis via HES1.
CDCA2 promotes tumorigenesis and induces radioresistance in oesophageal squamous cell carcinoma cells.
MFGE8 mitigates brain injury in a rat model of SAH by maintaining vascular endothelial integrity via TIGβ5/PI3K/CXCL12 signaling.
CXCL6 fuels the growth and metastases of esophageal squamous cell carcinoma cells both in vitro and in vivo through upregulation of PD-L1 via activation of STAT3 pathway.
The alterations of miRNA and mRNA expression profile and their integration analysis induced by silica nanoparticles in spermatocyte cells.
Hirsutanol A inhibits T-acute lymphocytic leukemia Jurkat cell viability through cell cycle arrest and p53-dependent induction of apoptosis.
Dihydroartemisinin inhibits endothelial cell migration via the TGF-β1/ALK5/SMAD2 signaling pathway.
MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and in vitro experiments.
miR-590-5p targets RMND5A and promotes migration in pancreatic adenocarcinoma cell lines.
Entry receptor bias in evolutionarily distant HSV-1 clinical strains drives divergent ocular and nervous system pathologies.
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
miR-665 inhibits epithelial-to-mesenchymal transition in bladder cancer via the SMAD3/SNAIL axis.
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
Metabolomic profiling of single enlarged lysosomes.
Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis.
Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.
A genetic variant conferred high expression of CAV2 promotes pancreatic cancer progression and associates with poor prognosis.
Long noncoding RNA IL6-AS1 is highly expressed in chronic obstructive pulmonary disease and is associated with interleukin 6 by targeting miR-149-5p and early B-cell factor 1.
Levosimendan in rats decreases acute kidney injury after cardiopulmonary resuscitation by improving mitochondrial dysfunction.
Activation of Interleukin-1β Release and Pyroptosis by Transmissible Gastroenteritis Virus Is Dependent on the NOD-Like Receptor Protein 3 Inflammasome in Porcine Intestinal Epithelial Cell Line.
Discovery of Potent Phosphodiesterase-9 Inhibitors for the Treatment of Hepatic Fibrosis.
7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis.
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3.
Alpha Enolase 1 Ubiquitination and Degradation Mediated by Ehrlichia chaffeensis TRP120 Disrupts Glycolytic Flux and Promotes Infection.
Upregulation of ARNTL2 is associated with poor survival and immune infiltration in clear cell renal cell carcinoma.
Obesity increases neuropathic pain via the AMPK-ERK-NOX4 pathway in rats.
EGR2-mediated regulation of m(6)A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization.
Comprehensive Analysis of Lysine Lactylation in Rice (Oryza sativa) Grains.
miR-139-5p mediates the palmitate-induced inhibition of insulin secretion by targeting neuronal pentraxin 1 in INS-1 cells.
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) and Treadmill Training on Recovery of Motor Function in a Rat Model of Partial Spinal Cord Injury.
MYOC Promotes the Differentiation of C2C12 Cells by Regulation of the TGF-β Signaling Pathways via CAV1.
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats.
METTL7B is a novel prognostic biomarker of lower-grade glioma based on pan-cancer analysis.
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma.
Early-senescent bone marrow mesenchymal stem cells promote C2C12 cell myogenic differentiation by preventing the nuclear translocation of FOXO3.
Zuojin Pill ameliorates inflammation in indomethacin-induced gastric injury via inhibition of MAPK pathway.
Retinoblastoma cell-derived exosomes promote angiogenesis of human vesicle endothelial cells through microRNA-92a-3p.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes.
HMGB1: an important regulator of myeloid differentiation and acute myeloid leukemia as well as a promising therapeutic target.
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization.
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Effect of acetate, β-hydroxybutyrate and their interaction on lipogenic gene expression, triglyceride contents and lipid droplet formation in dairy cow mammary epithelial cells.
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis.
YAP and Wnt3a independently promote AECIIs proliferation and differentiation by increasing nuclear β‑catenin expression in experimental bronchopulmonary dysplasia.
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Microarray expression profile analysis of circular RNAs and their potential regulatory role in bladder carcinoma.
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
A rare mutant of OFD1 gene responsible for Joubert syndrome with significant phenotype variation.
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
Upregulation Sestrin2 protects against hydrogen peroxide-induced oxidative damage bovine mammary epithelial cells via a Keap1-Nrf2/ARE pathway.
MicroRNA‑744‑5p is downregulated in colorectal cancer and targets SEPT2 to suppress the malignant phenotype.
CSN1 facilitates proliferation and migration of hepatocellular carcinoma cells by upregulating cyclin A2 expression.
Regulation of ABCG2 expression by Wnt5a through FZD7 in human pancreatic cancer cells.
Exogenous sodium hydrosulfide protects against high glucose‑induced injury and inflammation in human umbilical vein endothelial cells by inhibiting necroptosis via the p38 MAPK signaling pathway.
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Naringin attenuates renal interstitial fibrosis by regulating the TGF-β/Smad signaling pathway and inflammation.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Long noncoding RNA AK039312 and AK079370 inhibits bone formation via miR-199b-5p.
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling.
The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice.
Clonal Architectures Predict Clinical Outcome in Gastric Adenocarcinoma Based on Genomic Variation, Tumor Evolution, and Heterogeneity.
Overexpression of ICAT Inhibits the Progression of Colorectal Cancer by Binding with β-Catenin in the Cytoplasm.
S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.
Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization.
Suppression of TCAB1 expression induced cellular senescence by lessening proteasomal degradation of p21 in cancer cells.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension.
C1QTNF6 regulates cell proliferation and apoptosis of NSCLC in vitro and in vivo.
Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation.
Lectin-Mediated Binding of Engineered Lactococcus lactis to Cancer Cells.
Peptide OM-LV20 exerts neuroprotective effects against cerebral ischemia/reperfusion injury in rats.
ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase.
TGFβ-1 Induced Cross-Linking of the Extracellular Matrix of Primary Human Dermal Fibroblasts.
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53.
Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer.
Stability of Smyd1 in endothelial cells is controlled by PML-dependent SUMOylation upon cytokine stimulation.
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Structural basis of GABARAP-mediated GABA(A) receptor trafficking and functions on GABAergic synaptic transmission.
Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection.
Protective effect of thioredoxin reductase 1 in Parkinson's disease.
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Exosome carrying PSGR promotes stemness and epithelial-mesenchymal transition of low aggressive prostate cancer cells.
Deficiency of NEAT1 prevented MPP(+)-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277-5p/ARHGAP26 axis.
Dietary alpha-lipoic acid supplementation improves spermatogenesis and semen quality via antioxidant and anti-apoptotic effects in aged breeder roosters.
Disruption of P2X4 purinoceptor and suppression of the inflammation associated with cerebral aneurysm formation.
Tripchlorolide attenuates β-amyloid generation by inducing NEP activity in N2a/APP695 cells.
Vitamin D3 reduces hippocampal NR2A and anxiety in nicotine withdrawal mice.
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Integrative identification of the pathogenic role of a novel G6PD missense mutation c.697G>C.
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/β-catenin signaling.
Meningioma-associated protein 30 accelerates the proliferation and invasion of hepatocellular carcinoma by modulating Wnt/GSK-3β/β-catenin signaling.
BRCC36 functions noncatalytically to promote antiviral response by maintaining STAT1 protein stability.
DNA methylation determines the regulation of pregnane X receptor on CYP3A4 expression.
Melatonin inhibits RANKL‑induced osteoclastogenesis through the miR‑882/Rev‑erbα axis in Raw264.7 cells.
Effect of claudin 1 on cell proliferation, migration and apoptosis in human cervical squamous cell carcinoma.
Primary Cutaneous Aspergillosis in a Patient with CARD9 Deficiency and Aspergillus Susceptibility of Card9 Knockout Mice.
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible role in preeclampsia.
Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting the activation of cardiac fibroblasts.
RAB31 marks and controls an ESCRT-independent exosome pathway.
Overexpression of thioredoxin reductase 1 can reduce DNA damage, mitochondrial autophagy and endoplasmic reticulum stress in Parkinson's disease.
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
α-ketoglutarate delays age-related fertility decline in mammals.
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Imperatorin ameliorates mast cell-mediated allergic airway inflammation by inhibiting MRGPRX2 and CamKII/ERK signaling pathway.
Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission.
A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome.
Enhanced UV-B radiation affects AUR1 regulation of mitotic spindle morphology leading to aberrant mitosis.
G-Rh4 improves pancreatic β-cells dysfunction in vivo and in vitro by increased expression of Nrf2 and its target genes.
Yishen-tongbi decoction inhibits excessive activation of B cells by activating the FcγRIIb/Lyn/SHP-1 pathway and attenuates the inflammatory response in CIA rats.
Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.
Targeted-delivery of siRNA via a polypeptide-modified liposome for the treatment of gp96 over-expressed breast cancer.
A newly identified small molecular compound acts as a protein kinase inhibitor to suppress metastasis of colorectal cancer.
MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1α/PPAR-γ pathway.
Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation.
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Downregulation of IRAK3 by miR-33b-3p relieves chondrocyte inflammation and apoptosis in an in vitro osteoarthritis model.
Inhibition of Protein N-Glycosylation Blocks SARS-CoV-2 Infection.
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.
SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.
CALM1 promotes progression and dampens chemosensitivity to EGFR inhibitor in esophageal squamous cell carcinoma.
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Hippocampal LASP1 ameliorates chronic stress-mediated behavioral responses in a mouse model of unpredictable chronic mild stress.
Down-regulation of the Sp1 transcription factor by an increase of microRNA-4497 in human placenta is associated with early recurrent miscarriage.
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X.
Liraglutide preconditioning attenuates myocardial ischemia/ reperfusion injury via homer1 activation.
Dehydroevodiamine ameliorates indomethacin-induced gastric injury via inhibition of ERK and p38 signaling pathway.
CQMUH-011 mitigates autoimmune hepatitis via inhibiting the function of T lymphocytes.
Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway.
Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice.
Hypouricaemic and nephroprotective effects of Poria cocos in hyperuricemic mice by up-regulating ATP-binding cassette super-family G member 2.
CircRNA Lrp6 promotes cementoblast differentiation via miR-145a-5p/Zeb2 axis.
Semaphorin 3A promotes the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells in inflammatory environments by suppressing the Wnt/β-catenin signaling pathway.
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.
miR-483-3p Promotes IL-33 Production from Fibroblast-Like Synoviocytes by Regulating ERK Signaling in Rheumatoid Arthritis.
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Hypoxia Inhibits Proliferation of Human Dermal Lymphatic Endothelial Cells via Downregulation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 Expression.
HDAC9 in the Injury of Vascular Endothelial Cell Mediated by P38 MAPK Pathway.
Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induces p53-Mediated Apoptosis.
Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms.
LncRNA HLA-F-AS1 promotes colorectal cancer metastasis by inducing PFN1 in colorectal cancer-derived extracellular vesicles and mediating macrophage polarization.
Neferine improves oxidative stress and apoptosis in benign prostate hyperplasia via Nrf2-ARE pathway.
Baicalein pre-treatment alleviates hepatic ischemia/reperfusion injury in mice by regulating the Nrf2/ARE pathway.
Expression and role of interleukin-1β and associated biomarkers in deep vein thrombosis.
Knockdown of RREB1 inhibits cell proliferation via enhanced p16 expression in gastric cancer.
β2-adrenoreceptor agonist ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of mitochondrial biogenesis.
Inflammatory arthritis increases the susceptibility to acute immune-mediated hepatitis in mice through enhancing leptin expression in T cells.
A polydopamine-assisted strontium-substituted apatite coating for titanium promotes osteogenesis and angiogenesis via FAK/MAPK and PI3K/AKT signaling pathways.
Downregulation of Insulin-Like Growth Factor-1 Receptor Mediates Chondrocyte Death and Matrix Degradation in Kashin-Beck Disease.
MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.
Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.
Proto-oncogene tyrosine-protein kinase SRC (Src) inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models.
HIG1 domain family member 1A disrupts proliferation, migration, and invasion of colon adenocarcinoma cells.
MicroRNA-582-5p promotes triple-negative breast cancer invasion and metastasis by antagonizing CMTM8.
MicroRNA-301b-3p facilitates cell proliferation and migration in colorectal cancer by targeting HOXB1.
All-trans-retinoic acid suppresses rat embryo hindlimb bud mesenchymal chondrogenesis by modulating HoxD9 expression.
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Inhibition of micro RNA miR-122-5p prevents lipopolysaccharide-induced myocardial injury by inhibiting oxidative stress, inflammation and apoptosis via targeting GIT1.
Long non-coding RNA MCM3AP-AS1 protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced inflammation via regulating miR-138-5p/SIRT1.
Bushen Yijing Decoction (BSYJ) exerts an anti-systemic sclerosis effect via regulating MicroRNA-26a /FLI1 axis.
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
MicroRNA-30d target TIMP3 induces pituitary tumor cell growth and invasion.
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Screening and Identification of Differential Ovarian Proteins before and after Induced Ovulation via Seminal Plasma in Bactrian Camels.
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability.
Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway.
Rapamycin Suppresses Penile NADPH Oxidase Activity to Preserve Erectile Function in Mice Fed a Western Diet.
MicroRNA-7-5p Inhibits Migration, Invasion and Metastasis of Intrahepatic Cholangiocarcinoma by Inhibiting MyD88.
Cordycepin augments the chemosensitivity of osteosarcoma to cisplatin by activating AMPK and suppressing the AKT signaling pathway.
Host cells with transient overexpression of MDR1 as a novel in vitro model for evaluating on-target effect for activity against the epicellular Cryptosporidium parasite.
Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression.
Identification of the Key Genes Associated with the Yak Hair Follicle Cycle.
Ferroptosis-related gene signature correlates with the tumor immune features and predicts the prognosis of glioma patients.
Anti-Inflammatory Effects and Mechanisms of Pudilan Antiphlogistic Oral Liquid.
Heparanase-Induced Activation of AKT Stabilizes β-Catenin and Modulates Wnt/β-Catenin Signaling during Herpes Simplex Virus 1 Infection.
A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment.
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Role of clusterin in the regulation of trophoblast development and preeclampsia.
Circular RNA circRAB31 acts as a miR-885-5psponge to suppress gastric cancer progressionvia the PTEN/PI3K/AKT pathway.
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT.
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.
RNO3 QTL regulates vascular structure and arterial stiffness in the spontaneously hypertensive rat.
Vps33B in Dendritic Cells Regulates House Dust Mite-Induced Allergic Lung Inflammation.
BLM helicase inhibition synergizes with PARP inhibition to improve the radiosensitivity of olaparib resistant non-small cell lung cancer cells by inhibiting homologous recombination repair.
Changes in ion channel expression and function associated with cardiac arrhythmogenic remodeling by Sorbs2.
Peptide DR8 analogs alleviate pulmonary fibrosis via suppressing TGF-β1 mediated epithelial-mesenchymal transition and ERK1/2 pathway in vivo and in vitro.
Nicaraven inhibits TNFα-induced endothelial activation and inflammation through suppression of NF-κB signaling pathway.
Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.
LncRNA AFAP1-AS1 promotes M1 polarization of macrophages and osteogenic differentiation of valve interstitial cells.
Exosomes derived from mesenchymal stem cells curbs the progression of clear cell renal cell carcinoma through T-cell immune response.
Dysregulation of tumour microenvironment driven by circ-TPGS2/miR-7/TRAF6/NF-κB axis facilitates breast cancer cell motility.
LPS induces fibroblast-like synoviocytes RSC-364 cells to pyroptosis through NF-κB mediated dual signalling pathway.
Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.
Suppression of the USP10/CCND1 axis induces glioblastoma cell apoptosis.
Resveratrol Relieves Hyperoxia-Induced Brain Injury in Neonatal Rats by Activating Sirt1.
PLK2 protects retinal ganglion cells from oxidative stress by potentiating Nrf2 signaling via GSK-3β.
Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties.
Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers.
Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF-β/Smad signalling in type 2 diabetic rats.
HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F-actin signalling pathway.
miR‑451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B.
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.
Ponesimod protects against neuronal death by suppressing the activation of A1 astrocytes in early brain injury after experimental subarachnoid hemorrhage.
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
S100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer.
MSC-Derived Exosomes can Enhance the Angiogenesis of Human Brain MECs and Show Therapeutic Potential in a Mouse Model of Parkinson's Disease.
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression.
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
Compound 968 reverses adriamycin resistance in breast cancer MCF-7(ADR) cells via inhibiting P-glycoprotein function independently of glutaminase.
Novel Metabolic Regulation of Bile Acid Responses to Low Cholesterol in Whole-Grain-Diet-Fed Mice.
The Role of Cell Proliferation and Extracellular Matrix Accumulation Induced by Food Additive Butylated Hydroxytoluene in Uterine Leiomyoma.
Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor.
OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human.
Elevation of CSF Sortilin Following Subarachnoid Hemorrhage in Patients and Experimental Model Rats.
Protective autophagy attenuates soft substrate-induced apoptosis through ROS/JNK signaling pathway in breast cancer cells.
Inhibition of the Ras/ERK1/2 pathway contributes to the protective effect of ginsenoside Re against intimal hyperplasia.
N(7)-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression.
Age and gender differences in ACE2 and TMPRSS2 expressions in oral epithelial cells.
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
LncRNA KCNQ1OT1 activated by c-Myc promotes cell proliferation via interacting with FUS to stabilize MAP3K1 in acute promyelocytic leukemia.
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Phase separation of Epstein-Barr virus EBNA2 protein reorganizes chromatin topology for epigenetic regulation.
MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies.
Short-term standard alcohol consumption enhances platelet response to clopidogrel through inhibition of Nrf2/Ces1 pathway and induction of Cyp2c in mice.
Hippocampal miR-211-5p regulates neurogenesis and depression-like behaviors in the rat.
Methyltransferase like 13 mediates the translation of Snail in head and neck squamous cell carcinoma.
[6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling.
LncRNA-HAGLR motivates triple negative breast cancer progression by regulation of WNT2 via sponging miR-335-3p.
Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin.
Comparison of proteomic profiles from the testicular tissue of males with impaired and normal spermatogenesis.
Betaine prevented high-fat diet-induced NAFLD by regulating the FGF10/AMPK signaling pathway in ApoE(-/-) mice.
MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche.
Simvastatin Enhances Muscle Regeneration Through Autophagic Defect-Mediated Inflammation and mTOR Activation in G93ASOD1 Mice.
A novel model of constrictive pericarditis associated with myocardial fibrosis in rats.
Quercetin reverses TNF‑α induced osteogenic damage to human periodontal ligament stem cells by suppressing the NF‑κB/NLRP3 inflammasome pathway.
PCSK9 mediates the oxidative low‑density lipoprotein‑induced pyroptosis of vascular endothelial cells via the UQCRC1/ROS pathway.
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
Inhibition of PAI-1 Promotes Lipolysis and Enhances Weight Loss in Obese Mice.
Estrogen Regulates Endoplasmic Reticulum Stress-Mediated Apoptosis by ERK-p65 Pathway to Promote Endometrial Angiogenesis.
Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model.
FGF19 protects skeletal muscle against obesity-induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT-1/PGC-α pathway.
Long noncoding RNA H19 act as a competing endogenous RNA of Let-7g to facilitate IEC-6 cell migration and proliferation via regulating EGF.
MicroRNA‑592 promotes cell proliferation, migration and invasion in colorectal cancer by directly targeting SPARC.
Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway.
Triptolide inhibits human telomerase reverse transcriptase by downregulating translation factors SP1 and c-Myc in Epstein-Barr virus-positive B lymphocytes.
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect.
DDB1- and CUL4-associated factor 8 plays a critical role in spermatogenesis.
Syntaxin 3 interacts with serotonin transporter and regulates its function.
Effects of blood oxygen saturation on pulmonary artery remodeling in an in vitro perfusion circuit model.
EGFR/PPARδ/HSP90 pathway mediates cancer cell metabolism and chemoresistance.
Long non-coding RNA NEAT1 functions as a competing endogenous RNA to regulate S100A9 expression by sponging miR-196a-5p in rosacea.
Integrative analysis regarding the correlation between GAS2 family genes and human glioma prognosis.
Upregulation of LINC00511 expression by DNA hypomethylation promotes the progression of breast cancer.
The miR-146b-5p promotes Ewing's sarcoma cells progression via suppressing the expression of BTG2.
Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival.
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Iguratimod promotes transformation of mononuclear macrophages in elderly patients with rheumatoid arthritis by nuclear factor-κB pathway.
Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation.
Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.
Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice.
IP(6)-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion.
C/EBPα is indispensable for PML/RARα-mediated suppression of long non-coding RNA NEAT1 in acute promyelocytic leukemia cells.
An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy.
hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.
Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling.
Allicin attenuates myocardial apoptosis, inflammation and mitochondrial injury during hypoxia-reoxygenation: an in vitro study.
CSF-CN contributes to cancer-induced bone pain via the MKP-1-mediated MAPK pathway.
Anti-spastic effect induced by waggle needling correlates with KCC2-GABA(A) pathway in post-stroke spasticity rats.
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
Liver kinase B1 attenuates liver ischemia/reperfusion injury via inhibiting the NLRP3 inflammasome.
Amplification and expression of c-MET correlate with poor prognosis of patients with gastric cancer and upregulate the expression of PDL1.
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
N(6) -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
Everolimus regulates the activity of gemcitabine-resistant pancreatic cancer cells by targeting the Warburg effect via PI3K/AKT/mTOR signaling.
[Sitagliptin inhibits lipopolysaccharide-induced inflammatory response in human gingival fibroblasts by blocking nuclear factor-κB signaling pathway].
The neuroprotective effect of oxytocin on vincristine-induced neurotoxicity in mice.
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs.
MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.
Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts.
Inhibition of excessive mitophagy by N-acetyl-L-tryptophan confers hepatoprotection against Ischemia-Reperfusion injury in rats.
Hyaluronic acid ameliorates the proliferative ability of human amniotic epithelial cells through activation of TGF-β/BMP signaling.
Development and Characterisation of an in vitro Model of Wallerian Degeneration.
Olfactomedin-3 Enhances Seizure Activity by Interacting With AMPA Receptors in Epilepsy Models.
Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis.
miR-129-5p Inhibits Bone Formation Through TCF4.
MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.
A Novel Signature Constructed by RNA-Binding Protein Coding Genes to Improve Overall Survival Prediction of Glioma Patients.
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
An Aurora Kinase B-Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes.
Overexpression of Toll-Like Receptor 4 Affects Autophagy, Oxidative Stress, and Inflammatory Responses in Monocytes of Transgenic Sheep.
Changes of Gut Microbiota and Its Correlation With Short Chain Fatty Acids and Bioamine in Piglets at the Early Growth Stage.
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer.
miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis.
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
LncRNA GAS5 promotes apoptosis as a competing endogenous RNA for miR-21 via thrombospondin 1 in ischemic AKI.
SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model.
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
In-utero cold stress causes elevation of blood pressure via impaired vascular dopamine D(1) receptor in offspring.
Deletion of Bmal1 Impairs Pancreatic β-Cell Function via Mitochondrial Signaling Pathway.
Caulis Sargentodoxae Prescription Plays a Therapeutic Role with Decreased Inflammatory Cytokines in Peritoneal Fluid in the Rat Endometriosis Model.
Effect of Lentivirus-Mediated miR-499a-3p on Human Umbilical Vein Endothelial Cells.
Bushen Tiaojing (II and III) Decoctions Activate MAPK14 and MAPK3/1 to Promote the Expression of Cumulus Expansion-Related Factors in Mice.
Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress.
PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats.
Gender Difference on the Effect of Omega-3 Polyunsaturated Fatty Acids on Acetaminophen-Induced Acute Liver Failure.
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Neuroprotective Effect of the Inhibitor Salubrinal after Cardiac Arrest in a Rodent Model.
Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model.
Cordyceps cicadae Prevents Renal Tubular Epithelial Cell Apoptosis by Regulating the SIRT1/p53 Pathway in Hypertensive Renal Injury.
Shen Shuai II Recipe Attenuates Apoptosis in 5/6 Renal Ablation/Infarction Rats by Inhibiting p53 and the Mitochondrial Pathway of Apoptosis.
A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats.
Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model.
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT.
Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-α- and Interleukin-1β-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Oxygenase-1 Pathway.
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
RCC2 Expression Stimulates ER-Positive Breast Tumorigenesis.
The Effect of MicroRNA-101 on Angiogenesis of Human Umbilical Vein Endothelial Cells during Hypoxia and in Mice with Myocardial Infarction.
Mesenchymal Stem Cells Activate the MEK/ERK Signaling Pathway and Enhance DNA Methylation via DNMT1 in PBMC from Systemic Lupus Erythematosus.
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Exerts Anti-Breast Cancer Effect via miR-200c-PDE7B/PD-L1-AKT/MAPK Axis.
Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.
Akkermansia muciniphila Enhances the Antitumor Effect of Cisplatin in Lewis Lung Cancer Mice.
Ethanol Extract of the Infructescence of Platycarya strobilacea Sieb. et Zucc. Induces Methuosis of Human Nasopharyngeal Carcinoma Cells.
Combined Transplantation of Adipose Tissue-Derived Stem Cells and Endothelial Progenitor Cells Improve Diabetic Erectile Dysfunction in a Rat Model.
Ginkgetin Alleviates Inflammation, Oxidative Stress, and Apoptosis Induced by Hypoxia/Reoxygenation in H9C2 Cells via Caspase-3 Dependent Pathway.
Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40.
Decoy Receptor 3 Promotes Preosteoclast Cell Death via Reactive Oxygen Species-Induced Fas Ligand Expression and the IL-1α/IL-1 Receptor Antagonist Pathway.
Aminooxy-Acetic Acid Inhibits Experimental Autoimmune Uveitis by Modulating the Balance between Effector and Regulatory Lymphocyte Subsets.
ALKBH5-mediated m(6)A demethylation of lncRNA PVT1 plays an oncogenic role in osteosarcoma.
miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6.
PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway.
Haploinsufficiency of TANK-binding kinase 1 prepones age-associated neuroinflammatory changes without causing motor neuron degeneration in aged mice.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
High-trans fatty acid and high-sugar diets can cause mice with non-alcoholic steatohepatitis with liver fibrosis and potential pathogenesis.
Gypenosides regulate farnesoid X receptor-mediated bile acid and lipid metabolism in a mouse model of non-alcoholic steatohepatitis.
miR-197-3p Represses the Proliferation of Prostate Cancer by Regulating the VDAC1/AKT/β-catenin Signaling Axis.
The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer.
Septin4 promotes cell death in human colon cancer cells by interacting with BAX.
Transcriptome sequencing revealed that knocking down FOXL2 affected cell proliferation, the cell cycle, and DNA replication in chicken pre-ovulatory follicle cells.
Microarray Analysis of Long Non-Coding RNAs in Lung Tissues of Patients with COPD and HOXA-AS2 Promotes HPMECs Proliferation via Notch1.
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells.
RNA Binding Protein Motif 3 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Apoptosis Through Promoting Stress Granules Formation in PC12 Cells and Rat Primary Cortical Neurons.
Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy.
Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis.
Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway.
Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo.
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
Prognostic roles of miR-124-3p and its target ANXA7 and their effects on cell migration and invasion in hepatocellular carcinoma.
Linc01094 Accelerates the Growth and Metastatic-Related Traits of Glioblastoma by Sponging miR-126-5p.
miR-137-3p Modulates the Progression of Prostate Cancer by Regulating the JNK3/EZH2 Axis.
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Novel Alternatively Spliced Variants of Smad4 Expressed in TGF-β-Induced EMT Regulating Proliferation and Migration of A549 Cells.
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells.
Herpes Simplex Virus 1-Induced Blood-Brain Barrier Damage Involves Apoptosis Associated With GM130-Mediated Golgi Stress.
The Roles of Ubiquitination Factor E4B (UBE4B) in the Postoperative Prognosis of Patients with Renal Cell Carcinoma and in Renal Tumor Cells Growth and Metastasis.
Lysophosphatidic Acid Induces Apoptosis of PC12 Cells Through LPA1 Receptor/LPA2 Receptor/MAPK Signaling Pathway.
Antidepressant-Like Effect of Geniposide in Mice Exposed to a Chronic Mild Stress Involves the microRNA-298-5p-Mediated Nox1.
Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.
Dabigatran Suppresses PAR-1/SphK/S1P Activation of Astrocytes in Experimental Autoimmune Encephalomyelitis Model.
IFI30 Is a Novel Immune-Related Target with Predicting Value of Prognosis and Treatment Response in Glioblastoma.
Ellagic acid inhibits cell proliferation, migration, and invasion in melanoma via EGFR pathway.
4-hydroxy-2(3H)-benzoxazolone alleviates acetaminophen-induced hepatic injury by inhibiting NF-κB and activating Nrf2/HO-1 signaling pathways.
N6-methyladenosine methyltransferase METTL3 promotes colorectal cancer cell proliferation through enhancing MYC expression.
Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-β/Smad3 signaling and promoting angiogenesis.
CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1.
Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo.
Deficiency of Mitochondrial Functions and Peroxidation of Frontoparietal Cortex Enhance Isoflurane Sensitivity in Aging Mice.
Circular RNA Circ-ZNF609 Promotes Lung Adenocarcinoma Proliferation by Modulating miR-1224-3p/ETV1 Signaling.
Upregulation of DUSP14 Affects Proliferation, Invasion and Metastasis, Potentially via Epithelial-Mesenchymal Transition and Is Associated with Poor Prognosis in Pancreatic Cancer.
METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner.
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Metformin and LW6 impairs pancreatic cancer cells and reduces nuclear localization of YAP1.
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
The M6A methyltransferase METTL3 promotes the development and progression of prostate carcinoma via mediating MYC methylation.
Analysis of lncRNA, miRNA and mRNA-associated ceRNA networks and identification of potential drug targets for drug-resistant non-small cell lung cancer.
MiR-200a Regulates Nasopharyngeal Carcinoma Cell Migration and Invasion by Targeting MYH10.
P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition.
Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma.
Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma.
Long Noncoding RNA TCONS_00016406 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating the miR-687/PTEN Pathway.
Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis.
Astragalus Polysaccharides Inhibits Tumorigenesis and Lipid Metabolism Through miR-138-5p/SIRT1/SREBP1 Pathway in Prostate Cancer.
RNF183 Is a Prognostic Biomarker and Correlates With Tumor Purity, Immune Infiltrates in Uterine Corpus Endometrial Carcinoma.
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Bufei Jianpi Formula Improves Mitochondrial Function and Suppresses Mitophagy in Skeletal Muscle via the Adenosine Monophosphate-Activated Protein Kinase Pathway in Chronic Obstructive Pulmonary Disease.
Lycopene Exerts Neuroprotective Effects After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the Nuclear Factor Erythroid-2 Related Factor 2/Nuclear Factor-κ-Gene Binding Pathway.
Integrated Analysis of Key Genes and Pathways Involved in Fetal Growth Restriction and Their Associations With the Dysregulation of the Maternal Immune System.
Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils.
LncRNA NEAT1 Knockdown Inhibits Retinoblastoma Progression by miR-3619-5p/LASP1 Axis.
Long Non-coding RNA LINC01094 Promotes the Development of Clear Cell Renal Cell Carcinoma by Upregulating SLC2A3 via MicroRNA-184.
Soy Isoflavones Accelerate Glial Cell Migration via GPER-Mediated Signal Transduction Pathway.
Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling.
Coix Seed Oil Exerts an Anti-Triple-Negative Breast Cancer Effect by Disrupting miR-205/S1PR1 Axis.
An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid.
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
TRIM59 Protects Mice From Sepsis by Regulating Inflammation and Phagocytosis in Macrophages.
LncRNA NEAT1 Targets Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via the miR-410-3p/YY1 Axis.
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
MiR-224 Executes a Tumor Accelerative Role during Hepatocellular Carcinoma Malignancy by Targeting Cytoplasmic Polyadenylation Element-Binding Protein 3.
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Metformin activates the STING/IRF3/IFN-β pathway by inhibiting AKT phosphorylation in pancreatic cancer.
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial.
The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer.
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Interferon regulatory factor-1 suppresses DNA damage response and reverses chemotherapy resistance by downregulating the expression of RAD51 in gastric cancer.
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress.
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma.
CEBPG promotes esophageal squamous cell carcinoma progression by enhancing PI3K-AKT signaling.
miR-483-3p, Mediated by KLF9, Functions as Tumor Suppressor in Testicular Seminoma via Targeting MMP9.
Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling.
MicroRNA-1269a Promotes Proliferation and Arrest of Apoptosis of Glioma Cells by Directly Targeting ATRX.
LL-37-Induced Autophagy Contributed to the Elimination of Live Porphyromonas gingivalis Internalized in Keratinocytes.
siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways.
FGF18 Inhibits Clear Cell Renal Cell Carcinoma Proliferation and Invasion via Regulating Epithelial-Mesenchymal Transition.
Silencing of LncRNA C1RL-AS1 Suppresses the Malignant Phenotype in Gastric Cancer Cells via the AKT/β-Catenin/c-Myc Pathway.
Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down-Regulating PI3K/AKT Signaling Pathway.
PD-L1 Under Regulation of miR-429 Influences the Sensitivity of Gastric Cancer Cells to TRAIL by Binding of EGFR.
Natural Polyketides Isolated from the Endophytic Fungus Phomopsis sp. CAM212 with a Semisynthetic Derivative Downregulating the ERK/IκBα Signaling Pathways.
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
Obesity-Induced Increase in Cystatin C Alleviates Tissue Inflammation.
KLHL22 promotes malignant melanoma growth in vitro and in vivo by activating the PI3K/Akt/mTOR signaling pathway.
A novel m.11406 T > A mutation in mitochondrial ND4 gene causes MELAS syndrome.
HAP1 Modulates Epileptic Seizures by Regulating GABA(A)R Function in Patients with Temporal Lobe Epilepsy and in the PTZ-Induced Epileptic Model.
E2F7, regulated by miR‑30c, inhibits apoptosis and promotes cell cycle of prostate cancer cells.
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
Negative feedback loop of ERK/CREB/miR-212-3p inhibits HBeAg-induced macrophage activation.
Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral bone.
MicroRNA‑199a‑5p suppresses cell proliferation, migration and invasion by targeting ITGA3 in colorectal cancer.
KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-β/SMAD signaling pathway.
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
MicroRNA-19a-3p inhibits the cellular proliferation and invasion of non-small cell lung cancer by downregulating UBAP2L.
circANRIL reduces vascular endothelial injury, oxidative stress and inflammation in rats with coronary atherosclerosis.
BAG5 promotes invasion of papillary thyroid cancer cells via upregulation of fibronectin 1 at the translational level.
TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.
A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma.
Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway.
PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway.
Fetal bovine serum-derived exosomes regulate the adipogenic differentiation of human bone marrow mesenchymal stromal cells in a cross-species manner.
LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway.
Emodin protects against intestinal and lung injury induced by acute intestinal injury by modulating SP-A and TLR4/NF-κB pathway.
Multifactorial Attenuation of the Murine Heat Shock Response With Age.
AXL Inactivation Inhibits Mesothelioma Growth and Migration via Regulation of p53 Expression.
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Circular RNA GLIS2 promotes colorectal cancer cell motility via activation of the NF-κB pathway.
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Manganese exposure caused reproductive toxicity of male mice involving activation of GnRH secretion in the hypothalamus by prostaglandin E2 receptors EP1 and EP2.
Regulatory effects of the Uty/Ddx3y locus on neighboring chromosome Y genes and autosomal mRNA transcripts in adult mouse non-reproductive cells.
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
MicroRNA-92a serves as a risk factor in sepsis-induced ARDS and regulates apoptosis and cell migration in lipopolysaccharide-induced HPMEC and A549 cell injury.
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Time-resolved mRNA and miRNA expression profiling reveals crucial coregulation of molecular pathways involved in epithelial-pneumococcal interactions.
Galectin-3 inhibition attenuates doxorubicin-induced cardiac dysfunction by upregulating the expression of peroxiredoxin-4.
Tetrandrine sensitizes nasopharyngeal carcinoma cells to irradiation by inducing autophagy and inhibiting MEK/ERK pathway.
Downregulation of PER2 Promotes Tumor Progression by Enhancing Glycolysis via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Oral Squamous Cell Carcinoma.
TRADES: Targeted RNA Demethylation by SunTag System.
Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver.
SUMOylation of HSP27 regulates PKM2 to promote esophageal squamous cell carcinoma progression.
LINC01419 promotes cell proliferation and metastasis in hepatocellular carcinoma by enhancing NDRG1 promoter activity.
Azidothymidine (AZT) Inhibits Proliferation of Human Ovarian Cancer Cells by Regulating Cell Cycle Progression.
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.
The carboxyl-terminal di-lysine motif is essential for catalytic activity of UDP-glucuronosyltransferase 1A9.
CaMK4-dependent phosphorylation of Akt/mTOR underlies Th17 excessive activation in experimental autoimmune prostatitis.
MicroRNA-338 in MSCs-derived exosomes inhibits cardiomyocyte apoptosis in myocardial infarction.
Activated FMS-like tyrosine kinase 3 ameliorates angiotensin II-induced cardiac remodelling.
Intranasal administration of Cytoglobin modifies human umbilical cord‑derived mesenchymal stem cells and improves hypoxic‑ischemia brain damage in neonatal rats by modulating p38 MAPK signaling‑mediated apoptosis.
Roseburia intestinalis‑derived flagellin ameliorates colitis by targeting miR‑223‑3p‑mediated activation of NLRP3 inflammasome and pyroptosis.
Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis.
Members of the miR-30 family inhibit the epithelial-to-mesenchymal transition of non-small-cell lung cancer cells by suppressing XB130 expression levels.
Inhibitory effect of Lycium barbarum polysaccharide on sperm damage during cryopreservation.
Long non-coding RNA MEG3 promotes cataractogenesis by upregulating TP53INP1 expression in age-related cataract.
β-estradiol adjusts intestinal function via ERβ and GPR30 mediated PI3K/AKT signaling activation to alleviate postmenopausal dyslipidemia.
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Liraglutide, a glucagon-like peptide-1 receptor agonist, suppresses osteoclastogenesis through the inhibition of NF-κB and MAPK pathways via GLP-1R.
S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway.
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer.
Regulatory coupling between long noncoding RNAs and senescence in irradiated microglia.
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Circulating miR-27a-3p as a candidate for a biomarker of whole grain diets for lipid metabolism.
Loss of RAD6B induces degeneration of the cochlea in mice.
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice.
Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level.
Connecting METTL3 and intratumoural CD33(+) MDSCs in predicting clinical outcome in cervical cancer.
Long noncoding RNA Linc00337 functions as an E2F1 co-activator and promotes cell proliferation in pancreatic ductal adenocarcinoma.
Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.
Galectin-3 mediates high-glucose-induced cardiomyocyte injury by the NADPH oxidase/reactive oxygen species pathway.
Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma.
The mechanism of Arhalofenate in alleviating hyperuricemia-Activating PPARγ thereby reducing caspase-1 activity.
Blocking P2X7-Mediated Macrophage Polarization Overcomes Treatment Resistance in Lung Cancer.
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Pyrrolidinedithiocarbamic Acid Ammonium Salt Inhibits Apoptosis and Phenotypic Transformation of Co-Culture of Myeloma Cells and Renal Tubular Epithelial Cells by Reducing the Secretion of Light Chain Protein.
Transcription factor Kruppel-like factor 5 positively regulates the expression of AarF domain containing kinase 4.
N‑Myc induces the tumor progression of prostate cancer by regulating FSCN1.
Anti‑proliferative effect of honokiol on SW620 cells through upregulating BMP7 expression via the TGF‑β1/p53 signaling pathway.
lncRNA RASSF8‑AS1 suppresses the progression of laryngeal squamous cell carcinoma via targeting the miR‑664b‑3p/TLE1 axis.
Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide.
Inhibition of α1-adrenoceptor reduces TGF-β1-induced epithelial-to-mesenchymal transition and attenuates UUO-induced renal fibrosis in mice.
Pharmacological Effects of Fasudil on Flap Survival in a Rodent Model.
Functional variation of SLC52A3 rs13042395 predicts survival of Chinese gastric cancer patients.
MiRNA-1 promotes pyroptosis of cardiomyocytes and release of inflammatory factors by downregulating the expression level of PIK3R1 through the FoxO3a pathway.
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Melatonin inhibits Müller cell activation and pro-inflammatory cytokine production via upregulating the MEG3/miR-204/Sirt1 axis in experimental diabetic retinopathy.
Specific inhibition of FAK signaling attenuates subchondral bone deterioration and articular cartilage degeneration during osteoarthritis pathogenesis.
ITCH regulates oxidative stress induced by high glucose through thioredoxin interacting protein in cultured human lens epithelial cells.
Reduced IκBα promotes hepatocellular carcinoma cell proliferation and migration via regulation of NF-κB/Erbin axis.
Combined effect of recombinant human adenovirus p53 and curcumin in the treatment of liver cancer.
Effects of various levels of dietary fiber on carcass traits, meat quality and myosin heavy chain I, IIa, IIx and IIb expression in muscles in Erhualian and Large White pigs.
Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8-miR-10b-5p-WWC3 pathway.
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Deficiency of Notch signaling in pericytes results in arteriovenous malformations.
Asymmetrical effects of deafness-associated mitochondrial DNA 7516delA mutation on the processing of RNAs in the H-strand and L-strand polycistronic transcripts.
Expression and prognostic analyses of the insulin-like growth factor 2 mRNA binding protein family in human pancreatic cancer.
Therapeutic evaluation of palbociclib and its compatibility with other chemotherapies for primary and recurrent nasopharyngeal carcinoma.
Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis.
Targeting the NCOA3-SP1-TERT axis for tumor growth in hepatocellular carcinoma.
The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study.
Depletion of GPSM1 enhances ovarian granulosa cell apoptosis via cAMP-PKA-CREB pathway in vitro.
WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer.
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
NEAT1 regulates microtubule stabilization via FZD3/GSK3β/P-tau pathway in SH-SY5Y cells and APP/PS1 mice.
Tumor-associated macrophages induce PD-L1 expression in gastric cancer cells through IL-6 and TNF-ɑ signaling.
Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose.
Peptide DR8 suppresses epithelial-to-mesenchymal transition via the TGF-β/MAPK signaling pathway in renal fibrosis.
Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
CB2R agonist JWH-133 attenuates chronic inflammation by restraining M1 macrophage polarization via Nrf2/HO-1 pathway in diet-induced obese mice.
Small molecule inhibition of cyclic GMP-AMP synthase ameliorates sepsis-induced cardiac dysfunction in mice.
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
In vitro exposure to metformin activates human spermatozoa at therapeutically relevant concentrations.
XB130, regulated by miR-203, miR-219, and miR-4782-3p, mediates the proliferation and metastasis of non-small-cell lung cancer cells.
Cleavage of cyclic AMP-responsive element-binding protein H aggravates myocardial hypoxia reperfusion injury in a hepatocyte-myocardial cell co-culture system.
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
The Effect of Shen-Yuan-Dan Capsule on Autophagy-Related Gene Atg13 Promoter Methylation and Genomic Methylation Levels in Atherosclerotic Mice.
Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.
Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice.
Epidermal growth factor regulation by autophagy-mediated lncRNA H19 in murine intestinal tract after severe burn.
BZW2 promotes the malignant progression of colorectal cancer via activating the ERK/MAPK pathway.
Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway.
KIAA1429 promotes osteosarcoma progression by promoting stem cell properties and is regulated by miR-143-3p.
Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury.
Regulation of the small GTPase Ran by miR-802 modulates proliferation and metastasis in colorectal cancer cells.
Transcription factor 7-like 2 promotes osteogenic differentiation and boron-induced bone repair via lipocalin 2.
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
PIWIL4 Maintains HIV-1 Latency by Enforcing Epigenetically Suppressive Modifications on the 5' Long Terminal Repeat.
Fzd2 Contributes to Breast Cancer Cell Mesenchymal-Like Stemness and Drug Resistance.
Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis.
Ibudilast enhances the clearance of SOD1 and TDP-43 aggregates through TFEB-mediated autophagy and lysosomal biogenesis: The new molecular mechanism of ibudilast and its implication for neuroprotective therapy.
Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity.
Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication.
MEL endomorphins act as potent inflammatory analgesics with the inhibition of activated non-neuronal cells and modulation of pro-inflammatory cytokines.
ATP depletion induced cochlear hair cells death through histone deacetylation in vitro.
Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase.
Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway.
GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78.
Silybin enhances the blood concentration of brexpiprazole in rats by downregulating expression of CYP3A4 and CYP2D6.
The Endocannabinoid System Contributes to Memory Deficits Induced by Rapid-eye-movement Sleep Deprivation in Adolescent Mice.
Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p.
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
LncRNA FAM66C inhibits pancreatic cancer progression by sponging miR-574-3p.
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from the root of Averrhoa carambola L., protects against diabetic kidney disease by inhibiting TLR4/TGFβ signaling pathway.
LIN9 confers paclitaxel resistance in triple negative breast cancer cells by upregulating CCSAP.
Role of PEPT1in the transport of cinnabar in Caco-2 cells.
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
miR-137 and its target T-type Ca(V) 3.1 channel modulate dedifferentiation and proliferation of cerebrovascular smooth muscle cells in simulated microgravity rats by regulating calcineurin/NFAT pathway.
The inhibition of miR-17-5p promotes cortical neuron neurite growth via STAT3/GAP-43 pathway.
NIT2 overexpression predicts poor prognosis in tongue squamous cell carcinoma patients.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Malic enzyme 1 is important for uterine decidualization in response to progesterone/cAMP/PKA/HB-EGF pathway.
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Combined tazemetostat and MAPKi enhances differentiation of papillary thyroid cancer cells harbouring BRAF(V600E) by synergistically decreasing global trimethylation of H3K27.
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Overexpressed DAAM1 correlates with metastasis and predicts poor prognosis in breast cancer.
ROS/p53/miR‑335‑5p/Sp1 axis modulates the migration and epithelial to mesenchymal transition of JEG‑3 cells.
Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase-3β-mediated activation of autophagy.
UDP-Glucuronosyltransferase (UGT)-mediated attenuations of cytochrome P450 3A4 activity: UGT isoform-dependent mechanism of suppression.
Metastatic Melanoma Cells Rely on Sestrin2 to Acquire Anoikis Resistance via Detoxifying Intracellular ROS.
Ganoderal A effectively induces osteogenic differentiation of human amniotic mesenchymal stem cells via cross-talk between Wnt/β-catenin and BMP/SMAD signaling pathways.
CADM1 inhibits ovarian cancer cell proliferation and migration by potentially regulating the PI3K/Akt/mTOR pathway.
LncRNA-cCSC1 modulates cancer stem cell properties in colorectal cancer via activation of the Hedgehog signaling pathway.
M-phase phosphoprotein 8 promotes gastric cancer growth and metastasis via p53/Bcl-2 and EMT-related signaling pathways.
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
RIP1/RIP3/MLKL mediates dopaminergic neuron necroptosis in a mouse model of Parkinson disease.
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF(β-TRCP)-Mediated Degradation of NRF2 in Pancreatic Cancer.
LINC00680 and TTN-AS1 Stabilized by EIF4A3 Promoted Malignant Biological Behaviors of Glioblastoma Cells.
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
2-phenylethynesulfonamide inhibits growth of oral squamous cell carcinoma cells by blocking the function of heat shock protein 70.
LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.
Exosomes derived from human umbilical cord mesenchymal stem cells inhibit vein graft intimal hyperplasia and accelerate reendothelialization by enhancing endothelial function.
Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway.
Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation.
Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.
Impacts of Aerobic Exercise on Depression-Like Behaviors in Chronic Unpredictable Mild Stress Mice and Related Factors in the AMPK/PGC-1α Pathway.
Using ESTIMATE algorithm to establish an 8-mRNA signature prognosis prediction system and identify immunocyte infiltration-related genes in Pancreatic adenocarcinoma.
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.
SOX12 promotes the growth of multiple myeloma cells by enhancing Wnt/β-catenin signaling.
Carbon disulfide induced decidualization disorder in the mice uterus at the window of implantation.
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
The immunomodulatory role of irisin on osteogenesis via AMPK-mediated macrophage polarization.
Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage.
1,25-Dihydroxyvitamin D attenuates diabetic cardiac autophagy and damage by vitamin D receptor-mediated suppression of FoxO1 translocation.
Mitochondrial encephalopathy Due to a Novel Pathogenic Mitochondrial tRNA(Gln) m.4349C>T Variant.
Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling.
Oxidative stress induced pyroptosis leads to osteogenic dysfunction of MG63 cells.
Yu Gan Long Ameliorates Hepatic Fibrosis by Inhibiting PI3K/AKT, Ras/ERK and JAK1/STAT3 Signaling Pathways in CCl(4)-induced Liver Fibrosis Rats.
Recombinant HvRNASET2 protein induces marked connective tissue remodelling in the invertebrate model Hirudo verbana.
Genetic deletion of microRNA biogenesis in muscle cells reveals a hierarchical non-clustered network that controls focal adhesion signaling during muscle regeneration.
CircDDX17 acts as a competing endogenous RNA for miR-605 in breast cancer progression.
Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
Effects of Secreted frizzled-related protein 1 on inhibiting cardiac remodeling.
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
GRIM-19 deficiency promotes clear cell renal cell carcinoma progression and is associated with high TNM stage and Fuhrman grade.
Seminal Plasma Proteome as an Indicator of Sperm Dysfunction and Low Sperm Motility in Chickens.
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
Homer1a protects against neuronal injury via PI3K/AKT/mTOR signaling pathway.
Intra-Amniotic Delivery of CRMP4 siRNA Improves Mesenchymal Stem Cell Therapy in a Rat Spina Bifida Model.
Hfm1 participates in Golgi-associated spindle assembly and division in mouse oocyte meiosis.
Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age.
Proteomics analysis of tumor exosomes reveals vital pathways of Jinfukang inhibiting circulating tumor cells metastasis in lung cancer.
Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells.
PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target.
Tollip coordinates Parkin-dependent trafficking of mitochondrial-derived vesicles.
Different effects of total flavonoids from Arachniodes exilis on human umbilical cord mesenchymal stem cells in vitro.
Discovery of Isoplumbagin as a Novel NQO1 Substrate and Anti-Cancer Quinone.
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
The miR-532-3p/Chrdl1 axis regulates the proliferation and migration of amniotic fluid-derived mesenchymal stromal cells.
Bacterial Pigment Prodigiosin Demonstrates a Unique Antiherpesvirus Activity That Is Mediated through Inhibition of Prosurvival Signal Transducers.
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
PM(2.5)-inducible long non-coding RNA (NONHSAT247851.1) is a positive regulator of inflammation through its interaction with raf-1 in HUVECs.
Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling.
Lim Kinase1 regulates seizure activity via modulating actin dynamics.
2-((4-Arylpiperazin-1-yl)methyl)benzonitrile Derivatives as Orally Available Inhibitors of Hepatitis C Virus with a Novel Mechanism of Action.
Peripheral FGFR1 Regulates Myofascial Pain in Rats via the PI3K/AKT Pathway.
Nogo-B fosters HCC progression by enhancing Yap/Taz-mediated tumor-associated macrophages M2 polarization.
Sestrin2 overexpression alleviates hydrogen peroxide-induced apoptosis and oxidative stress in retinal ganglion cells by enhancing Nrf2 activation via Keap1 downregulation.
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
Calcitriol decreases live Porphyromonas gingivalis internalized into epithelial cells and monocytes by promoting autophagy.
Long Noncoding RNA LNC_000898 Alleviates Cardiomyocyte Apoptosis and Promotes Cardiac Repair After Myocardial Infarction Through Modulating the miR-375/PDK1 Axis.
LRIG3 represses cell motility by inhibiting slug via inactivating ERK signaling in human colorectal cancer.
Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.
The tumor suppressor NOR1 suppresses cell growth, invasiveness, and tumorigenicity in glioma.
G6PD facilitates clear cell renal cell carcinoma invasion by enhancing MMP2 expression through ROS‑MAPK axis pathway.
Maternal Treadmill Exercise Reduces the Neurotoxicity of Prenatal Sevoflurane Exposure in Rats via Activation of p300 Histone Acetyltransferase.
Transplantation of IFN-γ Primed hUCMSCs Significantly Improved Outcomes of Experimental Autoimmune Encephalomyelitis in a Mouse Model.
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Bidirectional interaction of lncRNA AFAP1-AS1 and CRKL accelerates the proliferative and metastatic abilities of hepatocarcinoma cells.
MicroRNA-214-3p enhances erastin-induced ferroptosis by targeting ATF4 in hepatoma cells.
miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1.
Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA‑MB‑231 cells.
Partial silencing of fucosyltransferase 8 gene expression inhibits proliferation of Ishikawa cells, a cell line of endometrial cancer.
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
MKP1 in the medial prefrontal cortex modulates chronic neuropathic pain via regulation of p38 and JNK1/2.
Upregulation of miR-92a-2-5p potentially contribute to anorectal malformations by inhibiting proliferation and enhancing apoptosis via PRKCA/β-catenin.
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Oocytes and hypoxanthine orchestrate the G2-M switch mechanism in ovarian granulosa cells.
hUMSC transplantation restores ovarian function in POI rats by inhibiting autophagy of theca-interstitial cells via the AMPK/mTOR signaling pathway.
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p- TGF-β1 axis.
Clinically relevant high levels of human C-reactive protein induces endothelial dysfunction and hypertension by inhibiting the AMPK-eNOS axis.
Long noncoding RNA NEAT1 sponges miR-129 to modulate renal fibrosis by regulation of collagen type I.
Dietary Glucose Increases Glucose Absorption and Lipid Deposition via SGLT1/2 Signaling and Acetylated ChREBP in the Intestine and Isolated Intestinal Epithelial Cells of Yellow Catfish.
Inhibition of microRNA-92a ameliorates lipopolysaccharide-induced endothelial barrier dysfunction by targeting ITGA5 through the PI3K/Akt signaling pathway in human pulmonary microvascular endothelial cells.
LncRNA NEAT1 promotes docetaxel resistance in prostate cancer by regulating ACSL4 via sponging miR-34a-5p and miR-204-5p.
Baicalein inhibits the growth of oral squamous cell carcinoma cells by downregulating the expression of transcription factor Sp1.
Bladder cancer cell‑secreted exosomal miR‑21 activates the PI3K/AKT pathway in macrophages to promote cancer progression.
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells.
Fusobacterium nucleatum Caused DNA Damage and Promoted Cell Proliferation by the Ku70/p53 Pathway in Oral Cancer Cells.
Auxiliary subunits control biophysical properties and response to compound NS5806 of the Kv4 potassium channel complex.
MiR-490-5p functions as tumor suppressor in childhood neuroblastoma by targeting MYEOV.
LncRNA MYCNOS facilitates proliferation and invasion in hepatocellular carcinoma by regulating miR-340.
Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.
Knockdown of SGK1 alleviates the IL-1β-induced chondrocyte anabolic and catabolic imbalance by activating FoxO1-mediated autophagy in human chondrocytes.
Liraglutide Lowers Body Weight Set Point in DIO Rats and its Relationship with Hypothalamic Microglia Activation.
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Neural stem cell-derived exosomes facilitate spinal cord functional recovery after injury by promoting angiogenesis.
Circular RNA USP1 regulates the permeability of blood-tumour barrier via miR-194-5p/FLI1 axis.
Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer.
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.
Histone deacetylase inhibitors differentially regulate c-Myc expression in retinoblastoma cells.
Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition.
Resveratrol alleviates obesity-associated podocyte injury in ovariectomized obese rats.
Downregulation of HMGB1 by miR-103a-3p Promotes Cell Proliferation, Alleviates Apoptosis and in Flammation in a Cell Model of Osteoarthritis.
RNA binding protein FXR1-miR301a-3p axis contributes to p21WAF1 degradation in oral cancer.
Human umbilical cord blood mononuclear cells protect against renal tubulointerstitial fibrosis in cisplatin-treated rats.
Inhibition of Peripheral ERK Signaling Ameliorates Persistent Muscle Pain Around Trigger Points in Rats.
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Critical role of IL-1β in the pathogenesis of Agrocybe aegerita galectin-induced liver injury through recruiting T cell to liver.
Amino Acid Mutations A286V and T437M in the Nucleoprotein Attenuate H7N9 Viruses in Mice.
The G Protein-Coupled Receptor FFAR2 Promotes Internalization during Influenza A Virus Entry.
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Type 2 inflammation suppression by T-regulatory cells attenuates the eosinophil recruitment in mucosa of chronic sinusitis.
MiR-30 family members inhibit osteoblast differentiation by suppressing Runx2 under unloading conditions in MC3T3-E1 cells.
Bridging molecules are secreted from the skeletal muscle and potentially regulate muscle differentiation.
Elevated lymphocyte specific protein 1 expression is involved in the regulation of leukocyte migration and immunosuppressive microenvironment in glioblastoma.
FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy.
Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis.
MicroRNA-639 is Down-Regulated in Hepatocellular Carcinoma Tumor Tissue and Inhibits Proliferation and Migration of Human Hepatocellular Carcinoma Cells Through the KAT7/Wnt/β-Catenin Pathway.
Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis.
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury.
Biomimetic anti-inflammatory nano-capsule serves as a cytokine blocker and M2 polarization inducer for bone tissue repair.
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Reverting chemoresistance of targeted agents by a ultrasoluble dendritic nanocapsule.
SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.
Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy.
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer.
CARLo-5 as an oncogenic gene in endometrial carcinoma.
Recombinant adiponectin peptide promotes neuronal survival after intracerebral haemorrhage by suppressing mitochondrial and ATF4-CHOP apoptosis pathways in diabetic mice via Smad3 signalling inhibition.
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome.
HOXC10 promotes proliferation and attenuates lipid accumulation of sheep bone marrow mesenchymal stem cells.
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Tumor suppressor LHPP regulates the proliferation of colorectal cancer cells via the PI3K/AKT pathway.
ZYZ-803, a novel hydrogen sulfide-nitric oxide conjugated donor, promotes angiogenesis via cross-talk between STAT3 and CaMKII.
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.
The MicroRNA-382-5p/MXD1 Axis Relates to Breast Cancer Progression and Promotes Cell Malignant Phenotypes.
α5-nAChR contributes to epithelial-mesenchymal transition and metastasis by regulating Jab1/Csn5 signalling in lung cancer.
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
Isoprenaline protects intestinal stem cells from chemotherapy-induced damage.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage.
Geniposide reduces cholesterol accumulation and increases its excretion by regulating the FXR-mediated liver-gut crosstalk of bile acids.
The expression of glucose transporters and mitochondrial division and fusion proteins in rats exposed to hypoxic preconditioning to attenuate propofol neurotoxicity.
Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours.
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
BRD7 suppresses invasion and metastasis in breast cancer by negatively regulating YB1-induced epithelial-mesenchymal transition.
The placental growth factor attenuates intimal hyperplasia in vein grafts by improving endothelial dysfunction.
RETRACTED: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing.
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Both IDO1 and TDO contribute to the malignancy of gliomas via the Kyn-AhR-AQP4 signaling pathway.
Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma.
Interactions between Viperin, Vesicle-Associated Membrane Protein A, and Hepatitis C Virus Protein NS5A Modulate Viperin Activity and NS5A Degradation.
[Mediated pathways of exosomes uptake by stem cells of apical papilla].
Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.
Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.
Conditioned medium derived from FGF-2-modified GMSCs enhances migration and angiogenesis of human umbilical vein endothelial cells.
Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits the proliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling.
Targeted silencing of miRNA-132-3p expression rescues disuse osteopenia by promoting mesenchymal stem cell osteogenic differentiation and osteogenesis in mice.
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Electrical Muscle Stimulation Accelerates Functional Recovery After Nerve Injury.
IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane.
GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy.
Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME.
MiR-21 modulates the polarization of macrophages and increases the effects of M2 macrophages on promoting the chemoresistance of ovarian cancer.
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification.
The biologically functional identification of a novel TIM3-binding peptide P26 in vitro and in vivo.
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation.
Let-7b regulates the adriamycin resistance of chronic myelogenous leukemia by targeting AURKB in K562/ADM cells.
Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing.
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Dendrobium candidum aqueous extract attenuates isoproterenol-induced cardiac hypertrophy through the ERK signalling pathway.
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway.
Oral cancer cell‑derived exosomes modulate natural killer cell activity by regulating the receptors on these cells.
Aberrant methylation‑mediated decrease of lncRNA HNF1A‑AS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT.
Protective effects of rapamycin on the retinal vascular bed during the vaso-obliteration phase in mouse oxygen-induced retinopathy model.
Bexarotene promotes microglia/macrophages - Specific brain - Derived Neurotrophic factor expression and axon sprouting after traumatic brain injury.
Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity.
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
circRNA 001306 enhances hepatocellular carcinoma growth by up-regulating CDK16 expression via sponging miR-584-5p.
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
Salvianolic acid B alleviates myocardial ischemic injury by promoting mitophagy and inhibiting activation of the NLRP3 inflammasome.
1,25(OH)2D3 inhibits osteogenic differentiation through activating β‑catenin signaling via downregulating bone morphogenetic protein 2.
IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Forkhead box P3 promotes breast cancer cell apoptosis by regulating programmed cell death 4 expression.
Inhibition of Histone Deacetylase 6 by Tubastatin A Attenuates the Progress of Osteoarthritis via Improving Mitochondrial Function.
Reduced expression of α2 integrin is involved in T-2 toxin-induced matrix degradation in C28/I2 cells and cartilages from rats administrated with T-2 toxin.
Cytoskeleton protein 4.1R regulates B-cell fate by modulating the canonical NF-κB pathway.
TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2.
The interplay between ATF2 and NEAT1 contributes to lung adenocarcinoma progression.
Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity.
lncRNA RP11-624L4.1 Is Associated with Unfavorable Prognosis and Promotes Proliferation via the CDK4/6-Cyclin D1-Rb-E2F1 Pathway in NPC.
Effects of dietary carbohydrate sources on lipid metabolism and SUMOylation modification in the liver tissues of yellow catfish.
Significance of gastrointestinal tract in the therapeutic mechanisms of exercise in depression: Synchronism between brain and intestine through GBA.
CircRNA circ-0038718 promotes hepatocellular carcinoma progression through sponging miR-139-3p.
Combination of metformin and RG7388 enhances inhibition of growth and induction of apoptosis of ovarian cancer cells through the PI3K/AKT/mTOR pathway.
Lipid peroxidation aggravates anti-tuberculosis drug-induced liver injury: Evidence of ferroptosis induction.
Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Genetic code expansion in mammalian cells: A plasmid system comparison.
Dexmedetomidine alleviates neurobehavioral impairments and myelination deficits following lipopolysaccharide exposure in early postnatal rats.
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Inhibition of Exo-miR-19a-3p derived from cardiomyocytes promotes angiogenesis and improves heart function in mice with myocardial infarction via targeting HIF-1α.
Tectorigenin Inhibits Glioblastoma Proliferation by G0/G1 Cell Cycle Arrest.
The peptide mimicking small extracellular ring domain of CD82 inhibits epithelial-mesenchymal transition by downregulating Wnt pathway and upregulating hippo pathway.
Metformin protects chondrocytes against IL-1β induced injury by regulation of the AMPK/NF-κ B signaling pathway.
Hydrogen sulfide accumulates LDL receptor precursor via downregulating PCSK9 in HepG2 cells.
Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Lung Injury in Rat Model of Bronchopulmonary Dysplasia by Affecting Cell Survival and Angiogenesis.
TL1A primed dendritic cells activation exacerbated chronic murine colitis.
Discovery of a novel rice-derived peptide with significant anti-gout potency.
Trophoblast H2S Maintains Early Pregnancy via Regulating Maternal-Fetal Interface Immune Hemostasis.
Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation.
Minocycline prevents the depressive-like behavior through inhibiting the release of HMGB1 from microglia and neurons.
Cadmium induces cell growth in A549 and HELF cells via autophagy-dependent glycolysis.
Inhibition of Phosphatidylinositol 3-Kinase γ by IPI-549 Attenuates Abdominal Aortic Aneurysm Formation in Mice.
TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening.
Heparanase potentiates the invasion and migration of pancreatic cancer cells via epithelial‑to‑mesenchymal transition through the Wnt/β‑catenin pathway.
PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β‑catenin signaling pathway.
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer.
STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.
Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner.
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Caprin-1 promotes HepG2 cell proliferation, invasion and migration and is associated with poor prognosis in patients with liver cancer.
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner.
Prazosin inhibits the proliferation, migration and invasion, but promotes the apoptosis of U251 and U87 cells via the PI3K/AKT/mTOR signaling pathway.
Selenoprotein S attenuates endothelial dysfunction in a diabetic vascular chip.
Tetramethylpyrazine attenuates endotoxin-induced retinal inflammation by inhibiting microglial activation via the TLR4/NF-κB signalling pathway.
circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling.
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Anti-inflammatory effect of Ganluyin, a Chinese classic prescription, in chronic pharyngitis rat model.
GOLGA4, A Golgi matrix protein, is dispensable for spermatogenesis and male fertility in mice.
SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.
Levobupivacaine inhibits proliferation and promotes apoptosis of breast cancer cells by suppressing the PI3K/Akt/mTOR signalling pathway.
Exosomal miR-532-5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5.
Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells.
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro.
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Circulating Myeloid-derived Suppressor Cells Facilitate Invasion of Thyroid Cancer Cells by Repressing miR-486-3p.
MAP kinase-interacting kinase 1 (MNK1) plays as a tumor suppressor in bladder cancer.
Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.
S-allylmercaptocysteine ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation and oxidative stress via nuclear factor kappa B and Keap1/Nrf2 pathways.
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Mortalin contributes to colorectal cancer by promoting proliferation and epithelial-mesenchymal transition.
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Marrow-derived mesenchymal stem cells regulate the inflammatory response and repair alveolar type II epithelial cells in acute lung injury of rats.
MicroRNA-378-3p/5p represses proliferation and induces apoptosis of oral squamous carcinoma cells via targeting KLK4.
RUNX3 inhibits the invasion and migration of esophageal squamous cell carcinoma by reversing the epithelial‑mesenchymal transition through TGF‑β/Smad signaling.
Osteopontin accelerates the development and metastasis of bladder cancer via activating JAK1/STAT1 pathway.
Lanthanum Chloride Impairs Learning and Memory and Induces Dendritic Spine Abnormality by Down-Regulating Rac1/PAK Signaling Pathway in Hippocampus of Offspring Rats.
AMPK facilitates intestinal long-chain fatty acid uptake by manipulating CD36 expression and translocation.
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
N(6)-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation.
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells.
Long-term Production of Glycogen and Hepatic-Derived, Cell-Invasion-Promoting Chemokines by Ultrasound-Driven Hepatic-Differentiated Human Bone Marrow Mesenchymal Stem Cells.
Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy.
miR-4458 directly targets IGF1R to inhibit cell proliferation and promote apoptosis in hemangioma.
Prior inhibition of AKT phosphorylation by BX795 can define a safer strategy to prevent herpes simplex virus-1 infection of the eye.
Self-Therapeutic Nanoparticle That Alters Tau Protein and Ameliorates Tauopathy Toward a Functional Nanomedicine to Tackle Alzheimer's.
MiR-142-3p Attenuates Oxygen Glucose Deprivation/Reoxygenation-Induced Injury by Targeting FBXO3 in Human Neuroblastoma SH-SY5Y Cells.
Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota-bile acid-farnesoid X receptor axis.
Cytoplasmic ERα and NFκB Promote Cell Survival in Mouse Mammary Cancer Cell Lines.
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Nasal delivery of a CRMP2-derived CBD3 adenovirus improves cognitive function and pathology in APP/PS1 transgenic mice.
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Tacr3 in the lateral habenula differentially regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia.
Overexpression of SLC6A1 associates with drug resistance and poor prognosis in prostate cancer.
Water extract from processed Polygonum multiflorum modulate gut microbiota and glucose metabolism on insulin resistant rats.
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.
ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis.
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
A novel ETV6-miR-429-CRKL regulatory circuitry contributes to aggressiveness of hepatocellular carcinoma.
Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins.
Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression-like behaviour via cannabinoid system in sleep deprivation rats.
ASK1 inhibits browning of white adipose tissue in obesity.
Integrin Subunit Alpha 5 (ITGA5) Gene Circular RNA Sponges microRNA-107 in Colorectal Carcinoma Cells and Tissues and Regulates the Expression of the Forkhead Box J3 (FOXJ3) Gene.
Increased Collagen Turnover Impairs Tendon Microstructure and Stability in Integrin α2β1-Deficient Mice.
MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line.
Characterisation of extraembryonic endoderm-like cells from mouse embryonic fibroblasts induced using chemicals alone.
FOXO4 expression associates with glioblastoma development and FOXO4 expression inhibits cell malignant phenotypes in vitro and in vivo.
MOB2 suppresses GBM cell migration and invasion via regulation of FAK/Akt and cAMP/PKA signaling.
Astaxanthin (ATX) enhances the intestinal mucosal functions in immunodeficient mice.
A low dose of AZD8055 enhances radiosensitivity of nasopharyngeal carcinoma cells by activating autophagy and apoptosis.
LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1α.
Hypoxia-induced feedback of HIF-1α and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization of p53 protein.
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Hydroxycarboxylic Acid Receptor 2 Is a Zika Virus Restriction Factor That Can Be Induced by Zika Virus Infection Through the IRE1-XBP1 Pathway.
Transcriptional Activation of Gstp1 by MEK/ERK Signaling Confers Chemo-Resistance to Cisplatin in Lung Cancer Stem Cells.
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Epigenetic-Mediated Downregulation of Zinc Finger Protein 671 (ZNF671) Predicts Poor Prognosis in Multiple Solid Tumors.
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Novel Breast-Specific Long Non-coding RNA LINC00993 Acts as a Tumor Suppressor in Triple-Negative Breast Cancer.
Influence of microcystins-LR (MC-LR) on autophagy in human neuroblastoma SK-N-SH cells.
Effects of microcystins-LR on genotoxic responses in human intestinal epithelial cells (NCM460).
The role of miR-130a-3p and SPOCK1 in tobacco exposed bronchial epithelial BEAS-2B transformed cells: Comparison to A549 and H1299 lung cancer cell lines.
Host factor SMYD3 is recruited by Ebola virus nucleoprotein to facilitate viral mRNA transcription.
Decreased Amino Acid Concentrations are Involved in Congenital Heart Disease.
Targeting Pin1 by All-Trans Retinoic Acid (ATRA) Overcomes Tamoxifen Resistance in Breast Cancer via Multifactorial Mechanisms.
Proteomic Profile of Carbonylated Proteins Screen the Regulation of Calmodulin-Dependent Protein Kinases-AMPK-Beclin1 in Aerobic Exercise-Induced Autophagy in Middle-Aged Rat Hippocampus.
miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways.
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
MicroRNA-582-3p negatively regulates cell proliferation and cell cycle progression in acute myeloid leukemia by targeting cyclin B2.
Down-regulation of miR-30b-5p protects cardiomyocytes against hypoxia-induced injury by targeting Aven.
PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer.
Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2.
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Chaihu-Shugan-San Reinforces CYP3A4 Expression via Pregnane X Receptor in Depressive Treatment of Liver-Qi Stagnation Syndrome.
Huangqi-Danshen Decoction Ameliorates Adenine-Induced Chronic Kidney Disease by Modulating Mitochondrial Dynamics.
A Compound of Chinese Herbs Protects against Alcoholic Liver Fibrosis in Rats via the TGF-β1/Smad Signaling Pathway.
Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression.
Curcumin Inhibits Proliferation of Epstein-Barr Virus-Associated Human Nasopharyngeal Carcinoma Cells by Inhibiting EBV Nuclear Antigen 1 Expression.
Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes.
Effect of Bufei Yishen Granules Combined with Electroacupuncture in Rats with Chronic Obstructive Pulmonary Disease via the Regulation of TLR-4/NF-κB Signaling.
UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells.
Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation.
Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson's Disease Cell Models.
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Glu-mGluR2/3-ERK Signaling Regulates Apoptosis of Hippocampal Neurons in Diabetic-Depression Model Rats.
Role of Cav-1 in HIV-1 Tat-Induced Dysfunction of Tight Junctions and Aβ-Transferring Proteins.
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
SIRT7 Regulates Lipopolysaccharide-Induced Inflammatory Injury by Suppressing the NF-κB Signaling Pathway.
Danggui Shaoyao San Ameliorates Renal Fibrosis via Regulation of Hypoxia and Autophagy.
Effect of Baoshenfang Formula on Podocyte Injury via Inhibiting the NOX-4/ROS/p38 Pathway in Diabetic Nephropathy.
A Network Pharmacology Approach for Uncovering the Osteogenic Mechanisms of Psoralea corylifolia Linn.
Neonatal Streptococcus pneumoniae Pneumonia Induces an Aberrant Airway Smooth Muscle Phenotype and AHR in Mice Model.
Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.
LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells.
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways.
Circular RNA MYLK promotes hepatocellular carcinoma progression by increasing Rab23 expression by sponging miR-362-3p.
LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b.
Proteomic analysis of human periodontal ligament cells under hypoxia.
The GLP-1 agonist, liraglutide, ameliorates inflammation through the activation of the PKA/CREB pathway in a rat model of knee osteoarthritis.
BRD4 Inhibitor AZD5153 Suppresses the Proliferation of Colorectal Cancer Cells and Sensitizes the Anticancer Effect of PARP Inhibitor.
Exosomes derived from Wharton's jelly of human umbilical cord mesenchymal stem cells reduce osteocyte apoptosis in glucocorticoid-induced osteonecrosis of the femoral head in rats via the miR-21-PTEN-AKT signalling pathway.
Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers.
miR-155-5p Promotes Dorsal Root Ganglion Neuron Axonal Growth in an Inhibitory Microenvironment via the cAMP/PKA Pathway.
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6.
Macrophage Colony-stimulating Factor Mediates the Recruitment of Macrophages in Triple negative Breast Cancer.
CREB1/Lin28/miR-638/VASP Interactive Network Drives the Development of Breast Cancer.
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.
Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Up-regulation of antioxidative proteins TRX1, TXNL1 and TXNRD1 in the cortex of PTZ kindling seizure model mice.
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Dexmedetomidine attenuates the neurotoxicity of propofol toward primary hippocampal neurons in vitro via Erk1/2/CREB/BDNF signaling pathways.
RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats.
Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.
Long Non-coding RNA KCNQ1OT1 Contributes to Antiepileptic Drug Resistance Through the miR-138-5p/ABCB1 Axis in vitro.
BAF45D Downregulation in Spinal Cord Ependymal Cells Following Spinal Cord Injury in Adult Rats and Its Potential Role in the Development of Neuronal Lesions.
Key Genes And Pathways Controlled By E2F1 In Human Castration-Resistant Prostate Cancer Cells.
MiR-200a-3p promoted the malignant behaviors of ovarian cancer cells through regulating PCDH9.
Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.
Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.
Transcription factor E2F1 positively regulates interferon regulatory factor 5 expression in non-small cell lung cancer.
Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression.
miR-29a inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting DPP4.
Prognostic significance and biological function of Lamina-associated polypeptide 2 in non-small-cell lung cancer.
The reversal of MRP1 expression induced by low-frequency and low-intensity ultrasound and curcumin mediated by VEGF in brain glioma.
Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling.
DEAD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells.
Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin.
MACC1 promotes angiogenesis in cholangiocarcinoma by upregulating VEGFA.
The overexpression of Rab9 promotes tumor progression regulated by XBP1 in breast cancer.
Elevated HOXA13 expression promotes the proliferation and metastasis of gastric cancer partly via activating Erk1/2.
LncRNA HOTAIRM1/HOXA1 Axis Promotes Cell Proliferation, Migration And Invasion In Endometrial Cancer.
FAT4-USP51 complex regulates the proliferation and invasion of endometrial cancer via Hippo pathway.
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
AIF-1 and RNASET2 Play Complementary Roles in the Innate Immune Response of Medicinal Leech.
Collagen prolyl 4-hydroxylase 2 predicts worse prognosis and promotes glycolysis in cervical cancer.
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies.
TINAGL1 promotes hepatocellular carcinogenesis through the activation of TGF-β signaling-medicated VEGF expression.
Disulfiram inhibits epithelial-mesenchymal transition through TGFβ-ERK-Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis.
lncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3β axis in hepatocellular carcinoma.
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Synergistic cytotoxicity of homoharringtonine and etoposide in acute myeloid leukemia cells involves disrupted antioxidant defense.
LncRNA SNHG16 Functions as an Oncogene by Sponging MiR-135a and Promotes JAK2/STAT3 Signal Pathway in Gastric Cancer.
RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma.
Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway.
Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells.
Dysregulation of MiR-519d Affects Oral Squamous Cell Carcinoma Invasion and Metastasis by Targeting MMP3.
CBX2 Regulates Proliferation and Apoptosis via the Phosphorylation of YAP in Hepatocellular Carcinoma.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism.
Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values.
Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.
Improved FGF21 Sensitivity and Restored FGF21 Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats After Duodenal-Jejunal Bypass and Sleeve Gastrectomy.
Hydroxytyrosol Improves Obesity and Insulin Resistance by Modulating Gut Microbiota in High-Fat Diet-Induced Obese Mice.
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
NF-κB-Dependent IFIT3 Induction by HBx Promotes Hepatitis B Virus Replication.
Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells.
Lovastatin Inhibits HIV-1-Induced MHC-I Downregulation by Targeting Nef-AP-1 Complex Formation: A New Strategy to Boost Immune Eradication of HIV-1 Infected Cells.
IL-19 Up-Regulates Mucin 5AC Production in Patients With Chronic Rhinosinusitis via STAT3 Pathway.
Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Maternal Nicotine Exposure During Gestation and Lactation Period Affects Behavior and Hippocampal Neurogenesis in Mouse Offspring.
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis.
FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response.
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Prazosin inhibits the growth and mobility of osteosarcoma cells.
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
Protective effect of histone methyltransferase NSD3 on ISO-induced cardiac hypertrophy.
The interaction of LOXL2 with GATA6 induces VEGFA expression and angiogenesis in cholangiocarcinoma.
Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus.
Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis.
Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis.
Tetramethylpyrazine downregulates transcription of the CXC receptor 4 (CXCR4) via nuclear respiratory factor‑1 (Nrf‑1) in WERI‑Rb1 retinoblastoma cells.
Adjunctive Chinese herbal medicine therapy for nasopharyngeal carcinoma: Clinical evidence and experimental validation.
Comparison of Pregnane X Receptor Antagonists for Enhancing the Antitumor Effect of Cisplatin.
Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model.
miR-15a-3p Suppresses Prostate Cancer Cell Proliferation and Invasion by Targeting SLC39A7 Via Downregulating Wnt/β-Catenin Signaling Pathway.
Two distinct E3 ligases, SCF(FBXL19) and HECW1, degrade thyroid transcription factor 1 in normal thyroid epithelial and follicular thyroid carcinoma cells, respectively.
In vitro photodynamic therapy of endothelial cells using hematoporphyrin monomethyl ether (Hemoporfin): Relevance to treatment of port wine stains.
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Overexpression of oncostatin M receptor regulates local immune response in glioblastoma.
Exogenous IL-19 mediates downregulation of TGF-β through Erk and p38 pathway to inhibit epidural fibrosis.
Localization of amyloid beta peptides to locus coeruleus and medial prefrontal cortex in corticotropin releasing factor overexpressing male and female mice.
Human TIGIT on porcine aortic endothelial cells suppresses xenogeneic macrophage-mediated cytotoxicity.
FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
MicroRNA‑671‑3p regulates the development of knee osteoarthritis by targeting TRAF3 in chondrocytes.
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Sodium ferulate attenuates high-glucose-induced oxidative injury in HT22 hippocampal cells.
Hydroxytyrosol prevents PM(2.5)-induced adiposity and insulin resistance by restraining oxidative stress related NF-κB pathway and modulation of gut microbiota in a murine model.
The balance of apoptosis and autophagy via regulation of the AMPK signal pathway in aging rat striatum during regular aerobic exercise.
Long noncoding RNA H19 promotes chemotherapy resistance in choriocarcinoma cells.
Methyl helicterate inhibits hepatic stellate cell activation through downregulating the ERK1/2 signaling pathway.
Novel synthetic tosyl chloride-berbamine regresses lethal MYC-positive leukemia by targeting CaMKIIγ/Myc axis.
Huaier extract enhances the treatment efficacy of imatinib in Ik6(+) Ph(+) acute lymphoblastic leukemia.
Prolyl hydroxylase 3 involvement in lung cancer progression under hypoxic conditions: association with hypoxia-inducible factor-1α and pyruvate kinase M2.
Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC.
STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1.
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Curcumin suppresses osteogenesis by inducing miR-126a-3p and subsequently suppressing the WNT/LRP6 pathway.
Optical control of protein phosphatase function.
Citreoviridin induces myocardial apoptosis through PPAR-γ-mTORC2-mediated autophagic pathway and the protective effect of thiamine and selenium.
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Neuroprotective effects of an Nrf2 agonist on high glucose-induced damage in HT22 cells.
Adenosine deaminase acting on RNA-1 (ADAR1) inhibits hepatitis B virus (HBV) replication by enhancing microRNA-122 processing.
The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice.
RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21.
Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma.
Cypermethrin exposure reduces the ovarian reserve by causing mitochondrial dysfunction in granulosa cells.
Icariin protects rotenone-induced neurotoxicity through induction of SIRT3.
Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement.
MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model.
A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence.
lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells.
Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer.
Minocycline Preserves the Integrity and Permeability of BBB by Altering the Activity of DKK1-Wnt Signaling in ICH Model.
Effects of PPARs/20-HETE on the renal impairment under diabetic conditions.
Multiple functional therapeutic effects of DL-3-n-butylphthalide in the cuprizone model of demyelination.
Angiogenin promotes colorectal cancer metastasis via tiRNA production.
The dietary freeze-dried fruit powder of Actinidia arguta ameliorates dextran sulphate sodium-induced ulcerative colitis in mice by inhibiting the activation of MAPKs.
Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats.
PD-L1 over-expression is driven by B-cell receptor signaling in diffuse large B-cell lymphoma.
Hexokinase 2 dimerization and interaction with voltage-dependent anion channel promoted resistance to cell apoptosis induced by gemcitabine in pancreatic cancer.
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Targeting PLIN2/PLIN5-PPARγ: Sulforaphane Disturbs the Maturation of Lipid Droplets.
Deciphering the multicomponent synergy mechanisms of SiNiSan prescription on irritable bowel syndrome using a bioinformatics/network topology based strategy.
Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing.
The Hypermethylation of Foxp3 Promoter Impairs the Function of Treg Cells in EAP.
Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats.
Leucine attenuates muscle atrophy and autophagosome formation by activating PI3K/AKT/mTOR signaling pathway in rotator cuff tears.
Circular HDAC9/microRNA-138/Sirtuin-1 Pathway Mediates Synaptic and Amyloid Precursor Protein Processing Deficits in Alzheimer's Disease.
Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers.
BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells.
Targeting miR-106-3p facilitates functional recovery via inactivating inflammatory microglia and interfering glial scar component deposition after neural injury.
A novel oncogene TRIM63 promotes cell proliferation and migration via activating Wnt/β-catenin signaling pathway in breast cancer.
Downregulation of thymopoietin by miR-139-5p suppresses cell proliferation and induces cell cycle arrest/apoptosis in pancreatic ductal adenocarcinoma.
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Circadian oscillations persist in low malignancy breast cancer cells.
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
CX-F9, a novel RSK2 inhibitor, suppresses cutaneous melanoma cells proliferation and metastasis through regulating autophagy.
Wnt7a, frequently silenced by CpG methylation, inhibits tumor growth and metastasis via suppressing epithelial-mesenchymal transition in gastric cancer.
Identification of reciprocal microRNA-mRNA pairs associated with metastatic potential disparities in human prostate cancer cells and signaling pathway analysis.
Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis.
Low-dose suspended graphene oxide nanosheets induce antioxidant response and osteogenic differentiation of bone marrow-derived mesenchymal stem cells via JNK-dependent FoxO1 activation.
Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences.
Progesterone promotes embryo adhesion by upregulating c-Fos/c-Jun transcription factor-mediated poFUT1 expression†.
ACTL6A regulates follicle-stimulating hormone-driven glycolysis in ovarian cancer cells via PGK1.
SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells.
Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells.
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
N(6)-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.
Trans-cinnamaldehyde shows anti-depression effect in the forced swimming test and possible involvement of the endocannabinoid system.
MiR-141-3p regulates proliferation and senescence of stem cells from apical papilla by targeting YAP.
Down-regulation of MARCO associates with tumor progression in hepatocellular carcinoma.
Arsenic trioxide inhibits angiogenesis in vitro and in vivo by upregulating FoxO3a.
Progranulin Decreases Susceptibility to Streptococcus pneumoniae in Influenza and Protects against Lethal Coinfection.
Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.
A one-step specific assay for continuous detection of sirtuin 2 activity.
Interleukin-6: Its role and mechanisms in rescuing depression-like behaviors in rat models of depression.
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
Caveolin-1 promotes Rfng expression via Erk-Jnk-p38 signaling pathway in mouse hepatocarcinoma cells.
GLI1 is increased in ovarian endometriosis and regulates migration, invasion and proliferation of human endometrial stromal cells in endometriosis.
Melatonin/PGC1A/UCP1 promotes tumor slimming and represses tumor progression by initiating autophagy and lipid browning.
Long non-coding RNA MYOSLID functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-29c-3p in gastric cancer.
5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-x(L).
Quantitative proteomics reveal the alterations in the spinal cord after myocardial ischemia‑reperfusion injury in rats.
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
MicroRNA‑203a‑3p is a candidate tumor suppressor that targets thrombospondin 2 in colorectal carcinoma.
BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis.
Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism.
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation.
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
NOD2 agonist murabutide alleviates radiation-induced injury through DNA damage response pathway mediated by ATR.
GRP94 promotes muscle differentiation by inhibiting the PI3K/AKT/mTOR signaling pathway.
MicroRNA-507 represses the malignant behaviors of non-small cell lung cancer via targeting zinc finger E-box binding homeobox 2.
Aspirin inhibits adipogenesis of tendon stem cells and lipids accumulation in rat injury tendon through regulating PTEN/PI3K/AKT signalling.
miR-183-5p acts as a potential prognostic biomarker in gastric cancer and regulates cell functions by modulating EEF2.
Spinosin and 6'''‑Feruloylspinosin protect the heart against acute myocardial ischemia and reperfusion in rats.
Mechanism of glycyrrhizin on ferroptosis during acute liver failure by inhibiting oxidative stress.
Involvement of CaMKII in regulating the release of diplotene-arrested mouse oocytes by pAkt1 (Ser473).
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Reprogramming the unfolded protein response for replication by porcine reproductive and respiratory syndrome virus.
EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production.
New FH peptide-modified ultrasonic nanobubbles for delivery of doxorubicin to cancer-associated fibroblasts.
Geraniol targets K(V)1.3 ion channel and exhibits anti-inflammatory activity in vitro and in vivo.
Citric acid modification of a polymer exhibits antioxidant and anti-inflammatory properties in stem cells and tissues.
Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model.
IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP.
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Comprehensive Identification of PTI Suppressors in Type III Effector Repertoire Reveals that Ralstonia solanacearum Activates Jasmonate Signaling at Two Different Steps.
CD90 serves as differential modulator of subcutaneous and visceral adipose-derived stem cells by regulating AKT activation that influences adipose tissue and metabolic homeostasis.
Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies.
Enhanced Hsa-miR-181d/p-STAT3 and Hsa-miR-181d/p-STAT5A Ratios Mediate the Anticancer Effect of Garcinol in STAT3/5A-Addicted Glioblastoma.
Protrudin modulates seizure activity through GABA(A) receptor regulation.
In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species.
Reshaping Prostate Tumor Microenvironment To Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem.
Pterostilbene Attenuates Experimental Atherosclerosis through Restoring Catalase-Mediated Redox Balance in Vascular Smooth Muscle Cells.
ER-mediated anti-tumor effects of shikonin on breast cancer.
The Molecular Mechanism of Sirt1 Signaling Pathway in Brain Injury of Newborn Rats Exposed to Hyperoxia.
Protective effect of peptide DR8 on bleomycin-induced pulmonary fibrosis by regulating the TGF-β/MAPK signaling pathway and oxidative stress.
Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1.
Microglial LOX-1/MAPKs/NF-κB positive loop promotes the vicious cycle of neuroinflammation and neural injury.
Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
Inhibition of microRNA-34a Suppresses Epileptiform Discharges Through Regulating Notch Signaling and Apoptosis in Cultured Hippocampal Neurons.
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1.
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients.
Effects of miRNA-342-3p in modulating Hedgehog signaling pathway of human umbilical cord mesenchymal stem cells by down-regulating Sufu.
Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
MARCH1 encourages tumour progression of hepatocellular carcinoma via regulation of PI3K-AKT-β-catenin pathways.
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
RANBP9 suppresses tumor proliferation in colorectal cancer.
The transcription factor E4bp4 regulates the expression and activity of Cyp3a11 in mice.
Microglia activation induces oxidative injury and decreases SIRT3 expression in dopaminergic neuronal cells.
Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession.
Alkaloids from Piper nigrum Synergistically Enhanced the Effect of Paclitaxel against Paclitaxel-Resistant Cervical Cancer Cells through the Downregulation of Mcl-1.
DUXAP10 inhibition attenuates the proliferation and metastasis of hepatocellular carcinoma cells by regulation of the Wnt/β-catenin and PI3K/Akt signaling pathways.
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
miR-27b-3p/MARCH7 regulates invasion and metastasis of endometrial cancer cells through Snail-mediated pathway.
TFAP2B overexpression contributes to tumor growth and progression of thyroid cancer through the COX-2 signaling pathway.
Long non-coding RNA PVT1 promotes autophagy as ceRNA to target ATG3 by sponging microRNA-365 in hepatocellular carcinoma.
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Downregulation of TSPAN13 by miR-369-3p inhibits cell proliferation in papillary thyroid cancer (PTC).
MiR-320a induces diabetic nephropathy via inhibiting MafB.
Using Caffeine and Free Amino Acids To Enhance the Transepithelial Transport of Catechins in Caco-2 Cells.
Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.
Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.
ALK5 signaling pathway mediates neurogenesis and functional recovery after cerebral ischemia/reperfusion in rats via Gadd45b.
Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.
Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats.
Downregulation of Calbindin 1 by miR-454-3p Suppresses Cell Proliferation in Nonsmall Cell Lung Cancer In Vitro.
Identification of novel PROM1 mutations responsible for autosomal recessive maculopathy with rod-cone dystrophy.
Inhibition of miR-214-5p attenuates inflammatory chemotaxis and nerve regeneration obstruction after spinal cord injury in rats.
Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells.
Mechanical cues modulate cellular uptake of nanoparticles in cancer via clathrin-mediated and caveolae-mediated endocytosis pathways.
The effect of early growth response 1 on levels of Amyloid-β 40 peptide in U87MG cells.
Slc6a13 deficiency promotes Th17 responses during intestinal bacterial infection.
MiR-31-5p acts as a tumor suppressor in renal cell carcinoma by targeting cyclin-dependent kinase 1 (CDK1).
TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway.
[Tristetraprolin inhibits autophagy in cultured lung cancer cells via the nuclear factor-κB pathway].
[Citron Rho-interacting serine/threonine kinase knockdown suppresses prostate cancer cell proliferation and metastasis by blocking Hippo-YAP pathway].
Increased cystatin F levels correlate with decreased cytotoxicity of cytotoxic T cells.
COMMD7 Regulates NF-κB Signaling Pathway in Hepatocellular Carcinoma Stem-like Cells.
IMB0901 inhibits muscle atrophy induced by cancer cachexia through MSTN signaling pathway.
Epigenetic Changes at the Birc5 Promoter Induced by YM155 in Synovial Sarcoma.
Antioxidative and Cardioprotective Effects of Schisandra chinensis Bee Pollen Extract on Isoprenaline-Induced Myocardial Infarction in Rats.
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
Tau modulates Schwann cell proliferation, migration and differentiation following peripheral nerve injury.
Role of Paip1 on angiogenesis and invasion in pancreatic cancer.
Social context-dependent singing alters molecular markers of dopaminergic and glutamatergic signaling in finch basal ganglia Area X.
MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells.
PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma.
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
Mannose receptor C type 2 mediates 1,25(OH)(2)D(3)/vitamin D receptor-regulated collagen metabolism through collagen type 5, alpha 2 chain and matrix metalloproteinase 13 in murine MC3T3-E1 cells.
ER stress contributes to high-fat diet-induced decrease of thyroglobulin and hypothyroidism.
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis.
Interference of DNAJB6/MRJ Isoform Switch by Morpholino Inhibits Replication of HIV-1 and RSV.
Glucose Is Involved in the Dynamic Regulation of m6A in Patients With Type 2 Diabetes.
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
HEV ORF3 downregulatesCD14 and CD64 to impair macrophages phagocytosis through inhibiting JAK/STAT pathway.
Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.
Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner.
Hepatic miR-181b-5p Contributes to Glycogen Synthesis Through Targeting EGR1.
RNase L facilitates the repair of DNA double-strand breaks through the nonhomologous end-joining pathway.
The E3 ubiquitin ligase HECW1 targets thyroid transcription factor 1 (TTF1/NKX2.1) for its degradation in the ubiquitin-proteasome system.
TGF-β-induced long non-coding RNA MIR155HG promotes the progression and EMT of laryngeal squamous cell carcinoma by regulating the miR-155-5p/SOX10 axis.
Immunoglobulin‑like transcript 4 and human leukocyte antigen‑G interaction promotes the progression of human colorectal cancer.
Dynamic bioenergetic alterations in colorectal adenomatous polyps and adenocarcinomas.
Umbilical Cord Blood Mesenchymal Stem Cells Enhance Lipopolysaccharide-Induced IL-10 and IL-37 Production in THP-1 Cells.
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
miR-618 Suppresses Metastasis in Gastric Cancer by Downregulating the Expression of TGF-β2.
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
TSP-1 is downregulated and inversely correlates with miR-449c expression in Cushing's disease.
C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo.
Trichostatin A‑induced miR‑30a‑5p regulates apoptosis and proliferation of keloid fibroblasts via targeting BCL2.
High expression of DLC family proteins predicts better prognosis and inhibits tumor progression in NSCLC.
CRKII overexpression promotes the in vitro proliferation, migration and invasion potential of murine hepatocarcinoma Hca-P cells.
Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice.
MiR-219a-5p enhances cisplatin sensitivity of human non-small cell lung cancer by targeting FGF9.
Salidroside inhibits migration and invasion of poorly differentiated thyroid cancer cells.
A Novel lncRNA IHS Promotes Tumor Proliferation and Metastasis in HCC by Regulating the ERK- and AKT/GSK-3β-Signaling Pathways.
lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer.
TLR2 promotes development and progression of human glioma via enhancing autophagy.
Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.
Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus.
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis.
KLF7 promotes polyamine biosynthesis and glioma development through transcriptionally activating ASL.
Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma.
Formiminotransferase Cyclodeaminase Suppresses Hepatocellular Carcinoma by Modulating Cell Apoptosis, DNA Damage, and Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Pathway.
Effect of CAPE-pNO(2) against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
Synergistic effects of 7-O-geranylquercetin and siRNAs on the treatment of human breast cancer.
Long noncoding RNA HOXA11-AS promotes gastric cancer cell proliferation and invasion via SRSF1 and functions as a biomarker in gastric cancer.
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling.
miR-21 promotes NLRP3 inflammasome activation to mediate pyroptosis and endotoxic shock.
Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells.
CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4(+) T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4(+) T cell enrichment in humanized mice.
MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling.
Blocking autophagy flux promotes interferon-alpha-mediated apoptosis in head and neck squamous cell carcinoma.
C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes.
Oxidative stress: One potential factor for arsenite-induced increase of N(6)-methyladenosine in human keratinocytes.
Panobinostat (LBH589) inhibits Wnt/β-catenin signaling pathway via upregulating APCL expression in breast cancer.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Mesenchymal stem cell-secreted factors delayed spermatogenesis injuries induced by busulfan involving intercellular adhesion molecule regulation.
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Treatment with a brain-selective prodrug of 17β-estradiol improves cognitive function in Alzheimer's disease mice by regulating klf5-NF-κB pathway.
Losartan protects against myocardial ischemia and reperfusion injury via vascular integrity preservation.
NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway.
eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop.
The long noncoding RNA NORAD enhances the TGF-β pathway to promote hepatocellular carcinoma progression by targeting miR-202-5p.
Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3.
MiR-511-5p functions as a tumor suppressor and a predictive of prognosis in colorectal cancer by directly targeting GPR116.
Fr‑HMGB1 and ds‑HMGB1 activate the kynurenine pathway via different mechanisms in association with depressive‑like behavior.
MicroRNA-124 regulates TRAF6 expression and functions as an independent prognostic factor in colorectal cancer.
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
Knockdown of endothelin receptor B inhibits the progression of triple-negative breast cancer.
PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-β1-induced EMT.
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
TRIM28 protects CARM1 from proteasome-mediated degradation to prevent colorectal cancer metastasis.
Inhibition of DHCR24 increases the cisplatin-induced damage to cochlear hair cells in vitro.
Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway.
Small Nucleolar RNA Host Gene 12 (SNHG12) Promotes Proliferation and Invasion of Laryngeal Cancer Cells via Sponging miR-129-5p and Potentiating WW Domain-Containing E3 Ubiquitin Protein Ligase 1 (WWP1) Expression.
Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients.
Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells.
Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis.
Effect of transcutaneous electrical acupoint stimulation on protecting against radiotherapy- induced ovarian damage in mice.
Sirtuin1 activator SRT2183 suppresses glioma cell growth involving activation of endoplasmic reticulum stress pathway.
F-box protein FBXO30 mediates retinoic acid receptor γ ubiquitination and regulates BMP signaling in neural tube defects.
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo.
Decline of p300 contributes to cell senescence and growth inhibition of hUC-MSCs through p53/p21 signaling pathway.
CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.
Cloning, expression of the truncation of recombinant peroxidase derived from millet bran and its reversal effects on 5-Fu resistance in colorectal cancer.
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway.
MicroRNA-31-5p enhances the Warburg effect via targeting FIH.
MiR-126-3p suppresses the growth, migration and invasion of NSCLC via targeting CCR1.
DLG5 suppresses breast cancer stem cell-like characteristics to restore tamoxifen sensitivity by inhibiting TAZ expression.
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Estrogen receptor variant ER-α36 promotes tamoxifen agonist activity in glioblastoma cells.
mircroRNA-152 prevents the malignant progression of atherosclerosis via down-regulation of KLF5.
Exendin-4 promotes actin cytoskeleton rearrangement and protects cells from Nogo-A-Δ20 mediated spreading inhibition and growth cone collapse by down-regulating RhoA expression and activation via the PI3K pathway.
Tetramethylpyrazine (TMP) ameliorates corneal neovascularization via regulating cell infiltration into cornea after alkali burn.
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
Silencing of Transcription Factor Sp1 Promotes SN1 Transporter Regulation by Ammonia in Mouse Cortical Astrocytes.
Long non-coding RNA Linc00320 inhibits glioma cell proliferation through restraining Wnt/β-catenin signaling.
Role of the P2X7 receptor in inflammation-mediated changes in the osteogenesis of periodontal ligament stem cells.
miR-632 promotes gastric cancer progression by accelerating angiogenesis in a TFF1-dependent manner.
Microvesicles from human adipose stem cells promote wound healing by optimizing cellular functions via AKT and ERK signaling pathways.
Aberrant methylation and downregulation of ZNF667-AS1 and ZNF667 promote the malignant progression of laryngeal squamous cell carcinoma.
PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε.
Circular RNA circMTO1 suppresses bladder cancer metastasis by sponging miR-221 and inhibiting epithelial-to-mesenchymal transition.
Long noncoding FOXD2-AS1 is activated by CREB1 and promotes cell proliferation and metastasis in glioma by sponging miR-185 through targeting AKT1.
Secalonic Acid-F, a Novel Mycotoxin, Represses the Progression of Hepatocellular Carcinoma via MARCH1 Regulation of the PI3K/AKT/β-catenin Signaling Pathway.
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway.
Retinal Neuron Is More Sensitive to Blue Light-Induced Damage than Glia Cell Due to DNA Double-Strand Breaks.
Engineering a conserved RNA regulatory protein repurposes its biological function in vivo.
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb.
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition.
miR-429 and miR-424-5p inhibit cell proliferation and Ca(2+) influx by downregulating CaSR in pulmonary artery smooth muscle cells.
Epigenetic changes in preterm birth placenta suggest a role for ADAMTS genes in spontaneous preterm birth.
Distribution patterns of the zebrafish neuronal intermediate filaments inaa and inab.
Effects of Platycodin D on S100A8/A9-induced inflammatory response in murine mammary carcinoma 4T1 cells.
Semaphoring 4D is required for the induction of antioxidant stress and anti-inflammatory effects of dihydromyricetin in colon cancer.
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
Establishment and evaluation of a novel mouse model of peri/postmenopausal depression.
Ginsenoside-Rb3 inhibits endothelial-mesenchymal transition of cardiac microvascular endothelial cells.
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
MicroRNA-155 Suppresses Mesangial Cell Proliferation and TGF-β1 Production via Inhibiting CXCR5-ERK Signaling Pathway in Lupus Nephritis.
TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways.
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Sema4D expression and secretion are increased by HIF-1α and inhibit osteogenesis in bone metastases of lung cancer.
Effects of hypothermia during propofol anesthesia on learning and memory ability and hippocampal apoptosis in neonatal rats.
Delivery of Glucosylceramidase Beta Gene Using AAV9 Vector Therapy as a Treatment Strategy in Mouse Models of Gaucher Disease.
Upregulation of miR-504-3p is associated with favorable prognosis of acute myeloid leukemia and may serve as a tumor suppressor by targeting MTHFD2.
MiR-202-3p functions as a tumor suppressor and reduces cell migration and invasion in papillary thyroid carcinoma.
Down-regulation of miR-1181 indicates a dismal prognosis for nasopharyngeal carcinoma and promoted cell proliferation and metastasis by modulating Wnt/β-catenin signaling.
Liver X receptor activation reduces gastric cancer cell proliferation by suppressing Wnt signalling via LXRβ relocalization.
Lysophosphatidic Acid Receptor 6 (LPAR6) Expression and Prospective Signaling Pathway Analysis in Breast Cancer.
Lanthanum Chloride Impairs the Blood-Brain Barrier Integrity by Reduction of Junctional Proteins and Upregulation of MMP-9 in Rats.
Paeonol-mediated apoptosis of hepatocellular carcinoma cells by NF-κB pathway.
Estradiol promotes EMT in endometriosis via MALAT1/miR200s sponge function.
Decreased α-tubulin acetylation induced by an acidic environment impairs autophagosome formation and leads to rat cardiomyocyte injury.
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
Down-regulated expressed protein HMGB3 inhibits proliferation and migration, promotes apoptosis in the placentas of fetal growth restriction.
Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos.
FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in Glioma.
Scutellarin synergistically enhances cisplatin effect against ovarian cancer cells through enhancing the ability of cisplatin binding to DNA.
Caspase 3/ROCK1 pathway mediates high glucose-induced platelet microparticles shedding.
Insulin in high concentration recede cigarette smoke extract induced cellular senescence of airway epithelial cell through autophagy pathway.
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Integrative Analysis Revealing Human Adipose-Specific Genes and Consolidating Obesity Loci.
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17.
Taurine protected As(2)O(3)-induced the activation of hepatic stellate cells through inhibiting PPARα-autophagy pathway.
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
ATXN2L upregulated by epidermal growth factor promotes gastric cancer cell invasiveness and oxaliplatin resistance.
RNA Helicase A Is an Important Host Factor Involved in Dengue Virus Replication.
MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer.
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
MiR-141-3p functions as a tumor suppressor through directly targeting ZFR in non-small cell lung cancer.
MiR-223-3p functions as a tumor suppressor in lung squamous cell carcinoma by miR-223-3p-mutant p53 regulatory feedback loop.
LncRNA MIAT sponges miR-149-5p to inhibit efferocytosis in advanced atherosclerosis through CD47 upregulation.
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involving Nrf2.
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization.
Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model.
Epigenetic hypomethylation and upregulation of GD3s in triple negative breast cancer.
TRIM21 Mitigates Human Lung Microvascular Endothelial Cells' Inflammatory Responses to LPS.
Oxymatrine protects against l-arginine-induced acute pancreatitis and intestine injury involving Th1/Th17 cytokines and MAPK/NF-κB signalling.
Protective role of N-acetyl-l-tryptophan against hepatic ischemia-reperfusion injury via the RIP2/caspase-1/IL-1β signaling pathway.
Liraglutide promotes autophagy by regulating the AMPK/mTOR pathway in a rat remnant kidney model of chronic renal failure.
MiR-506-3p suppresses the proliferation of ovarian cancer cells by negatively regulating the expression of MTMR6.
Targeting YAP suppresses ovarian cancer progression through regulation of the PI3K/Akt/mTOR pathway.
High concentration of chemerin caused by ovarian hyperandrogenism may lead to poor IVF outcome in polycystic ovary syndrome: a pilot study.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Protective effect of metformin on a rat model of lipopolysaccharide-induced preeclampsia.
Exosomes from human-bone-marrow-derived mesenchymal stem cells protect against renal ischemia/reperfusion injury via transferring miR-199a-3p.
MiR-92b-3p promotes neurite growth and functional recovery via the PTEN/AKT pathway in acute spinal cord injury.
Loss of MsrB1 perturbs spatial learning and long-term potentiation/long-term depression in mice.
APOBEC3A is a prominent cytidine deaminase in breast cancer.
Regional and temporal regulation and role of somatostatin receptor subtypes in the mouse brain following systemic kainate-induced acute seizures.
Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages.
Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition.
Nevirapine inhibits migration and invasion in dedifferentiated thyroid cancer cells.
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Overexpressed ITGA2 promotes malignant tumor aggression by up-regulating PD-L1 expression through the activation of the STAT3 signaling pathway.
Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation.
Enterovirus 71 VP1 Protein Regulates Viral Replication in SH-SY5Y Cells via the mTOR Autophagy Signaling Pathway.
Biosynthetic CircRNA_001160 induced by PTBP1 regulates the permeability of BTB via the CircRNA_001160/miR-195-5p/ETV1 axis.
Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.
Graphene Quantum Dots Induce Autophagy and Reveal Protection Against Hydrogen Peroxide-Induced Oxidative Stress Injury.
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Gestational B-vitamin supplementation alleviates PM(2.5)-induced autism-like behavior and hippocampal neurodevelopmental impairment in mice offspring.
Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation.
DACT1 Involvement in the Cytoskeletal Arrangement of Cardiomyocytes in Atrial Fibrillation by Regulating Cx43.
COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats.
Potential role of microRNA-424 in regulating ERRγ to suppress trophoblast proliferation and invasion in fetal growth restriction.
Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts.
Effects of antisense lncRNA PCBP1-AS1 on biological behaviors of vulvar squamous carcinoma cells by regulating TRAF5 and NF-κB expression.
hnRNPM, a potential mediator of YY1 in promoting the epithelial-mesenchymal transition of prostate cancer cells.
Sequential application of bFGF and BMP-2 facilitates osteogenic differentiation of human periodontal ligament stem cells.
Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery.
Tizanidine hydrochloride exhibits a cytotoxic effect on osteosarcoma cells through the PI3K/AKT signaling pathway.
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
CHD1L is associated with poor survival and promotes the proliferation and metastasis of intrahepatic cholangiocarcinoma.
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Mutation in NPPA causes atrial fibrillation by activating inflammation and cardiac fibrosis in a knock-in rat model.
LncRNA MAGI2-AS3 inhibits hepatocellular carcinoma cell proliferation and migration by targeting the miR-374b-5p/SMG1 signaling pathway.
Reduced PDGF-AA in subchondral bone leads to articular cartilage degeneration after strenuous running.
Long noncoding RNA SOX21-AS1 promotes cervical cancer progression by competitively sponging miR-7/VDAC1.
Long non-coding RNA LINC00526 represses glioma progression via forming a double negative feedback loop with AXL.
The Expression of MBD6 Is Associated with Tumor Size in Uterine Leiomyomas.
Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway.
MiR-543-5p inhibits inflammation and promotes nerve regeneration through inactivation of the NF-κB in rats after spinal cord injury.
Upregulation of miR‑95-3p inhibits growth of osteosarcoma by targeting HDGF.
IDH2 compensates for IDH1 mutation to maintain cell survival under hypoxic conditions in IDH1‑mutant tumor cells.
Potential role of the cAMP/PKA/CREB signalling pathway in hypoxic preconditioning and effect on propofol‑induced neurotoxicity in the hippocampus of neonatal rats.
SDF1/CXCR4 axis plays a role in angiogenesis during the degeneration of intervertebral discs.
MicroRNA-338-3p suppresses cell proliferation, migration and invasion in human malignant melanoma by targeting MACC1.
Oxaliplatin reverses the GLP-1R-mediated promotion of intrahepatic cholangiocarcinoma by altering FoxO1 signaling.
Curcumin suppresses intestinal microvascular endothelial cells invasion and angiogenesis induced by activated platelets.
MicroRNA-23b-3p promotes the proliferation, migration, and epithelial-mesenchymal transition of lens epithelial cells by targeting Sprouty2.
UFL1 modulates NLRP3 inflammasome activation and protects against pyroptosis in LPS-stimulated bovine mammary epithelial cells.
IgE Aggravates the Senescence of Smooth Muscle Cells in Abdominal Aortic Aneurysm by Upregulating LincRNA-p21.
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
miR-448 targets IDO1 and regulates CD8(+) T cell response in human colon cancer.
Ginsenoside compound K ameliorates imiquimod-induced psoriasis-like dermatitis through inhibiting REG3A/RegIIIγ expression in keratinocytes.
Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway.
Verification of osteoblast differentiation on airborne-particle abrasion, large-grit, acid-etched surface of titanium implants regulated by yes-associated protein and transcriptional coactivator with PDZ-binding motif.
PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis.
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
Overexpression of RACK1 enhanced the replication of porcine reproductive and respiratory syndrome virus in Marc-145 cells and promoted the NF-κB activation via upregulating the expression and phosphorylation of TRAF2.
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress.
Interferon regulatory factor-1 reverses chemoresistance by downregulating the expression of P-glycoprotein in gastric cancer.
Exogenous H(2)S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD(+)-SIRT3 pathway in cardiac tissues of db/db mice.
Identification of proteomic signatures associated with COPD frequent exacerbators.
Titania nanotubes promote osteogenesis via mediating crosstalk between macrophages and MSCs under oxidative stress.
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
STAG2 loss-of-function mutation induces PD-L1 expression in U2OS cells.
IL-37 attenuates allergic process via STAT6/STAT3 pathways in murine allergic rhinitis.
Uridine-cytidine kinase 2 upregulation predicts poor prognosis of hepatocellular carcinoma and is associated with cancer aggressiveness.
Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells.
Baicalin induced colon cancer cells apoptosis through miR-217/DKK1-mediated inhibition of Wnt signaling pathway.
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
The orphan nuclear receptor RORα is a potential endogenous protector in renal ischemia/reperfusion injury.
Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro.
Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P-glycoprotein.
NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats.
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
The long noncoding RNA TPTE2P1 promotes the viability of colorectal cancer cells.
MicroRNA-129-1-3p regulates cyclic stretch-induced endothelial progenitor cell differentiation by targeting Runx2.
Metabolic Profiling of Tumors, Sera, and Skeletal Muscles from an Orthotopic Murine Model of Gastric Cancer Associated-Cachexia.
A fixation method for the optimisation of western blotting.
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
Long non-coding RNA LOC284454 promotes migration and invasion of nasopharyngeal carcinoma via modulating the Rho/Rac signaling pathway.
Hepatitis C Virus-Induced FUT8 Causes 5-FU Drug Resistance in Human Hepatoma Huh7.5.1 Cells.
The Shigella type three secretion system effector OspF invades host nucleus by binding host importin α1.
Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27.
Zinc-finger protein YY1 suppresses tumor growth of human nasopharyngeal carcinoma by inactivating c-Myc-mediated microRNA-141 transcription.
Epigallocatechin-3-gallate inhibits angiotensin II-induced cardiomyocyte hypertrophy via regulating Hippo signaling pathway in H9c2 rat cardiomyocytes.
Renalase attenuates mitochondrial fission in cisplatin-induced acute kidney injury via modulating sirtuin-3.
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
S100A4-MYH9 Axis Promote Migration and Invasion of Gastric Cancer Cells by Inducing TGF-β-Mediated Epithelial-Mesenchymal Transition.
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
A Chinese Herbal Formula Ameliorates Pulmonary Fibrosis by Inhibiting Oxidative Stress via Upregulating Nrf2.
MAPK Phosphatase-1 Deficiency Exacerbates the Severity of Imiquimod-Induced Psoriasiform Skin Disease.
Bacillus amyloliquefaciens Ameliorates Dextran Sulfate Sodium-Induced Colitis by Improving Gut Microbial Dysbiosis in Mice Model.
Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx.
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial-Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling.
Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.
CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription.
The lncKLF6/KLF6 feedback loop regulates the growth of non-small cell lung cancer.
CDC20 regulates cardiac hypertrophy via targeting LC3-dependent autophagy.
Protective Role of Nuclear Factor-Erythroid 2-Related Factor 2 Against Radiation-Induced Lung Injury and Inflammation.
SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.
Hypoxia-induced hyperpermeability of rat glomerular endothelial cells involves HIF-2α mediated changes in the expression of occludin and ZO-1.
Long-Noncoding RNA Colorectal Neoplasia Differentially Expressed Gene as a Potential Target to Upregulate the Expression of IRX5 by miR-136-5P to Promote Oncogenic Properties in Hepatocellular Carcinoma.
β-Arrestin2 Inhibits Expression of Inflammatory Cytokines in BEAS-2B Lung Epithelial Cells Treated with Cigarette Smoke Condensate via Inhibition of Autophagy.
Curcumin Inhibits Polyethylene-Induced Osteolysis via Repressing NF-κB Signaling Pathway Activation.
Transient High-Glucose Stimulation Induces Persistent Inflammatory Factor Secretion from Rat Glomerular Mesangial Cells via an Epigenetic Mechanism.
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
Overexpression of Toll-Like Receptor 4 Contributes to Phagocytosis of Salmonella Enterica Serovar Typhimurium via Phosphoinositide 3-Kinase Signaling in Sheep.
CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8.
Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis.
TIFA Promotes Cell Survival and Migration in Lung Adenocarcinoma.
A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains.
Allograft Inflammatory Factor-1 Mediates Macrophage-Induced Impairment of Insulin Signaling in Adipocytes.
RIP140/PGC-1α axis involved in vitamin A-induced neural differentiation by increasing mitochondrial function.
Renal Denervation Effects on Myocardial Fibrosis and Ventricular Arrhythmias in Rats with Ischemic Cardiomyopathy.
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
MicroRNA-223 Regulates Cardiac Fibrosis After Myocardial Infarction by Targeting RASA1.
Lipocalin 2 Suppresses Ocular Inflammation by Inhibiting the Activation of NF-κβ Pathway in Endotoxin-Induced Uveitis.
Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway.
abLIM1 constructs non-erythroid cortical actin networks to prevent mechanical tension-induced blebbing.
MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1.
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Resveratrol Inhibits the TGF-β1-Induced Proliferation of Cardiac Fibroblasts and Collagen Secretion by Downregulating miR-17 in Rat.
Estradiol Alleviates Intervertebral Disc Degeneration through Modulating the Antioxidant Enzymes and Inhibiting Autophagy in the Model of Menopause Rats.
γδT Cells Exacerbate Podocyte Injury via the CD28/B7-1-Phosphor-SRC Kinase Pathway.
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Proteomic Profile of Carbonylated Proteins Screen Regulation of Apoptosis via CaMK Signaling in Response to Regular Aerobic Exercise.
Hypoxia-mediated miR-212-3p downregulation enhances progression of intrahepatic cholangiocarcinoma through upregulation of Rab1a.
The miR-199a-3p regulates the radioresistance of esophageal cancer cells via targeting the AK4 gene.
R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.
Tetrandrine enhances radiosensitivity through the CDC25C/CDK1/cyclin B1 pathway in nasopharyngeal carcinoma cells.
FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1α/CEACAM5 functional axis.
Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression.
NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cells.
Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2).
Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.
Photothermal exposure of polydopamine-coated branched Au-Ag nanoparticles induces cell cycle arrest, apoptosis, and autophagy in human bladder cancer cells.
Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus.
Inhibition of Connexin 43 and Phosphorylated NR2B in Spinal Astrocytes Attenuates Bone Cancer Pain in Mice.
Adipocyte ADRB3 Down-Regulated in Chinese Overweight Individuals Adipocyte ADRB3 in Overweight.
High expression of Capn4 is associated with metastasis and poor prognosis in esophageal squamous cell carcinoma.
Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro.
PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation.
CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway.
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo.
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
MicroRNA-144-3p inhibits cell proliferation and induces cell apoptosis in prostate cancer by targeting CEP55.
Aldosterone downregulates delayed rectifier potassium currents through an angiotensin type 1 receptor-dependent mechanism.
Advanced maternal age impairs spatial learning capacity in young adult mouse offspring.
LncRNA MALAT1 promotes relapse of breast cancer patients with postoperative fever.
HJC0152, a novel STAT3 inhibitor with promising anti-tumor effect in gastric cancer.
DNA Methylation Profiling Reveals the Change of Inflammation-Associated ZC3H12D in Leukoaraiosis.
The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia.
Aberrant expression of stress-induced phosphoprotein 1 in colorectal cancer and its clinicopathologic significance.
Electroacupuncture Alleviated Neuronal Apoptosis Following Ischemic Stroke in Rats via Midkine and ERK/JNK/p38 Signaling Pathway.
Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway.
Increased expression of CHOP and LC3B in newborn rats with bronchopulmonary dysplasia.
Knockdown of NUPR1 inhibits the growth of U266 and RPMI8226 multiple myeloma cell lines via activating PTEN and caspase activation‑dependent apoptosis.
HOXA5 is a tumor suppressor gene that is decreased in gastric cancer.
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
MicroRNA-222 Promotes Invasion and Metastasis of Papillary Thyroid Cancer Through Targeting Protein Phosphatase 2 Regulatory Subunit B Alpha Expression.
Human CD31 on porcine cells suppress xenogeneic neutrophil-mediated cytotoxicity via the inhibition of NETosis.
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity.
Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
Decreased expression of TROAP suppresses cellular proliferation, migration and invasion in gastric cancer.
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Protein kinase C-mediated impairment of glutamine outward transport and SN1 transporter distribution by ammonia in mouse cortical astrocytes.
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
MicroRNA-519d-3p inhibits cell proliferation and migration by targeting TROAP in colorectal cancer.
Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats.
Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells.
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
Effects of Guanfu total base on Bcl-2 and Bax expression and correlation with atrial fibrillation.
Adipose-specific expression of mouse Rbp7 gene and its developmental and metabolic changes.
SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression.
Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway.
mRNAs are sorted for export or degradation before passing through nuclear speckles.
The selective Nlrp3 inflammasome inhibitor Mcc950 attenuates lung ischemia-reperfusion injury.
UCH-L1 inhibition aggravates mossy fiber sprouting in the pentylenetetrazole kindling model.
CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer.
STING positively regulates human ORMDL3 expression through TBK1-IRF3-STAT6 complex mediation.
The LncRNA MALAT1 regulates CD80 transcription via the NF-κB signaling pathway in the A549 cell line.
Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-κB signaling pathways.
Knockdown of ribosomal protein S15A inhibits proliferation of breast cancer cells through induction of apoptosis in vitro.
2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside potentiates self-renewal of human dental pulp stem cells via the AMPK/ERK/SIRT1 axis.
Dual-functionality of RASSF1A overexpression in A375 cells is mediated by activation of IL-6/STAT3 regulatory loop.
Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer.
PSMB4 overexpression enhances the cell growth and viability of breast cancer cells leading to a poor prognosis.
MicroRNA-409-3p suppresses cell proliferation and cell cycle progression by targeting cyclin D2 in papillary thyroid carcinoma.
Eugenol protects the transplanted heart against ischemia/reperfusion injury in rats by inhibiting the inflammatory response and apoptosis.
Long non-coding RNA FTH1P3 regulated metastasis and invasion of esophageal squamous cell carcinoma through SP1/NF-kB pathway.
miR-497 may enhance the sensitivity of non-small cell lung cancer cells to gefitinib through targeting the insulin-like growth factor-1 receptor.
A Pre-Clinical Large Animal Model of Sustained Liver Injury and Regeneration Stimulus.
Proteomic profile in the mussel Perna viridis after short-term exposure to the brown tide alga Aureococcus anophagefferens.
Long non-coding RNA OGFRP1 regulates LYPD3 expression by sponging miR-124-3p and promotes non-small cell lung cancer progression.
Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury.
A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.
Increased expression of heat shock factor 1 (HSF1) is associated with poor survival in gastric cancer patients.
Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α.
1α,25-dihydroxyvitamin D3 promotes osseointegration of titanium implant via downregulating AGEs/RAGE pathway in T2DM.
Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high-fat diet-fed mice.
Identification of a Novel Function of Resveratrol and Genistein as a Regulator of β(2) -Adrenergic Receptor Expression in Skeletal Muscle Cells and Characterization of Promoter Elements Required for Promoter Activation.
β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors.
mRNA m(6)A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.
Overexpression of Epsin 3 enhances migration and invasion of glioma cells by inducing epithelial‑mesenchymal transition.
Possible Involvement of PTEN Signaling Pathway in the Anti-apoptotic Effect of Electroacupuncture Following Ischemic Stroke in Rats.
Role of dihydroartemisinin in regulating prostaglandin E(2) synthesis cascade and inflammation in endothelial cells.
Protocatechuic acid inhibits the growth of ovarian cancer cells by inducing apoptosis and autophagy.
MiR-1301-3p inhibits human breast cancer cell proliferation by regulating cell cycle progression and apoptosis through directly targeting ICT1.
Upregulation of HSP60 expression in the postnatal rat cochlea and rats with drug-induced hearing loss.
CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4‑activated MEK/ERK and PI3K/AKT pathways.
Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes.
Downregulation of 5-hydroxytryptamine receptor 3A expression exerts an anticancer activity against cell growth in colorectal carcinoma cells in vitro.
Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition.
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
Solute Carrier Organic Anion Transporter Family Member 3A1 Is a Bile Acid Efflux Transporter in Cholestasis.
Novel Podophyllotoxin Derivatives as Potential Tubulin Inhibitors: Design, Synthesis, and Antiproliferative Activity Evaluation.
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
MiR-133a acts as an anti-oncogene in Hepatocellular carcinoma by inhibiting FOSL2 through TGF-β/Smad3 signaling pathway.
Knockdown of LncRNA MALAT1 contributes to cell apoptosis via regulating NF-κB/CD80 axis in neonatal respiratory distress syndrome.
Screening of differentially expressed proteins from syncytiotrophoblast for severe early-onset preeclampsia in women with gestational diabetes mellitus using tandem mass tag quantitative proteomics.
On the use of abiotic sialic acids to attenuate cell inflammation.
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
The pro-metastasis effect of circANKS1B in breast cancer.
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
Saponins from Boussingaultia gracilis prevent obesity and related metabolic impairments in diet-induced obese mice.
Retraction: Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.
Downregulation of LINC00894-002 Contributes to Tamoxifen Resistance by Enhancing the TGF-β Signaling Pathway.
Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.
Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells.
EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma.
The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion.
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway.
Downregulation of microRNA-142-3p and its tumor suppressor role in gastric cancer.
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Targeted silencing of the ADP-ribosyltransferase 3 gene inhibits the migration ability of melanoma cells.
Downregulation of TACC3 inhibits tumor growth and migration in osteosarcoma cells through regulation of the NF-κB signaling pathway.
BTB/POZ domain-containing protein 7 is inversely associated with fibronectin expression in salivary adenoid cystic carcinoma.
After Treatment with Methylene Blue is Effective against Delayed Encephalopathy after Acute Carbon Monoxide Poisoning.
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
BACH1 promotes the progression of human colorectal cancer through BACH1/CXCR4 pathway.
The NK1 receptor antagonist NKP608 inhibits proliferation of human colorectal cancer cells via Wnt signaling pathway.
Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity.
Targeting mTORC1/2 Complexes Inhibit Tumorigenesis and Enhance Sensitivity to 5-Flourouracil (5-FU) in Hepatocellular Carcinoma: A Preclinical Study of mTORC1/2-Targeted Therapy in Hepatocellular Carcinoma (HCC).
Neuroglobin mediates neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in rats through preserving the activity of Na(+)/K(+) ATPases.
6-Formylindolo(3,2-b)carbazole induced aryl hydrocarbon receptor activation prevents intestinal barrier dysfunction through regulation of claudin-2 expression.
MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma.
HSF4 transcriptional regulates HMOX-1 expression in HLECs.
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
Long noncoding RNA TUG1 facilitates osteogenic differentiation of periodontal ligament stem cells via interacting with Lin28A.
Interfering RNA against PKC-α inhibits TNF-α-induced IP(3)R1 expression and improves glomerular filtration rate in rats with fulminant hepatic failure.
Reduced-gliotoxin induces ROS-mediated anoikis in human colorectal cancer cells.
Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma.
SOX4 contributes to TGF-β-induced epithelial-mesenchymal transition and stem cell characteristics of gastric cancer cells.
Exogenous hydrogen sulfide protects human umbilical vein endothelial cells against high glucose‑induced injury by inhibiting the necroptosis pathway.
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
UBAP2L silencing inhibits cell proliferation and G2/M phase transition in breast cancer.
In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.
Effects of intrathecal bupivacaine on the NR2B/CaMKIIα/CREB signaling pathway in the rat lumbar spinal cord.
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Prognostic significance of sodium-potassium ATPase regulator, FXYD3, in human hepatocellular carcinoma.
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis.
Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome.
[Expression of DKKL1 in spermatozoa of men with asthenospermia].
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer.
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
SOX8 regulates cancer stem-like properties and cisplatin-induced EMT in tongue squamous cell carcinoma by acting on the Wnt/β-catenin pathway.
Roles of high-mobility group box 1 and thrombin in murine pulmonary fibrosis and the therapeutic potential of thrombomodulin.
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Pyrethroid Insecticide Cypermethrin Modulates Gonadotropin Synthesis via Calcium Homeostasis and ERK1/2 Signaling in LβT2 Mouse Pituitary Cells.
Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance-Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator-Activated Receptor α Activation.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
B7-H6 expression is induced by lipopolysaccharide and facilitates cancer invasion and metastasis in human gliomas.
Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling.
NIK‑ and IKKβ‑binding protein contributes to gastric cancer chemoresistance by promoting epithelial‑mesenchymal transition through the NF‑κB signaling pathway.
Inhibition of HSP90α protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression.
Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells.
Association of HMGB1, BRCA1 and P62 expression in ovarian cancer and chemotherapy sensitivity.
Tumor necrosis factor receptor 2 may promote the proliferation and drug resistance of Kapras299 and L428 lymphoma cells via the AKT and WNT/β-catenin signaling pathways.
Knockdown of serine/threonine protein phosphatase 5 enhances gemcitabine sensitivity by promoting apoptosis in pancreatic cancer cells in vitro.
Knockdown of stromal interaction molecule 1 inhibits proliferation of colorectal cancer cells by inducing apoptosis.
Small interfering RNA-mediated silencing of G-protein-coupled receptor 137 inhibits growth of osteosarcoma cells.
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Baicalein inhibits growth of Epstein-Barr virus-positive nasopharyngeal carcinoma by repressing the activity of EBNA1 Q-promoter.
HuR regulates telomerase activity through TERC methylation.
STAT3 activation by IL-6 from adipose-derived stem cells promotes endometrial carcinoma proliferation and metastasis.
Chemotherapy-Induced Long Non-coding RNA 1 Promotes Metastasis and Chemo-Resistance of TSCC via the Wnt/β-Catenin Signaling Pathway.
MiR-199a-3p affects the multi-chemoresistance of osteosarcoma through targeting AK4.
Host Factor SPCS1 Regulates the Replication of Japanese Encephalitis Virus through Interactions with Transmembrane Domains of NS2B.
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
α-Viniferin activates autophagic apoptosis and cell death by reducing glucocorticoid receptor expression in castration-resistant prostate cancer cells.
Air pollution is associated with the development of atherosclerosis via the cooperation of CD36 and NLRP3 inflammasome in ApoE(-/-) mice.
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Chronic low-dose exposure of nonylphenol alters energy homeostasis in the reproductive system of female rats.
Robust, pleiotropic drug resistance 5 (Pdr5)-mediated multidrug resistance is vigorously maintained in Saccharomyces cerevisiae cells during glucose and nitrogen limitation.
Rho-kinase inhibitor Y-27632 downregulates LPS-induced IL-6 and IL-8 production via blocking p38 MAPK and NF-κB pathways in human gingival fibroblasts.
Harmine, a small molecule derived from natural sources, inhibits enterovirus 71 replication by targeting NF-κB pathway.
Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice.
Tumor necrosis factor receptor-associated factor 6 mediated the promotion of salivary adenoid cystic carcinoma progression through Smad-p38-JNK signaling pathway induced by TGF-β.
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Interferon-induced protein 35 inhibits endothelial cell proliferation, migration and re-endothelialization of injured arteries by inhibiting the nuclear factor-kappa B pathway.
Icariside II alleviates oxygen-glucose deprivation and reoxygenation-induced PC12 cell oxidative injury by activating Nrf2/SIRT3 signaling pathway.
Long non-coding RNA CRNDE promotes heptaocellular carcinoma cell proliferation by regulating PI3K/Akt /β-catenin signaling.
Adoptive Transfer of Interleukin-21-stimulated Human CD8+ T Memory Stem Cells Efficiently Inhibits Tumor Growth.
The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20.
LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling.
Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction.
The Role of the RhoA/ROCK Signaling Pathway in Mechanical Strain-Induced Scleral Myofibroblast Differentiation.
Conditioned medium from overly excitatory primary astrocytes induced by La(3+) increases apoptosis in primary neurons via upregulating the expression of NMDA receptors.
Cell-laden and orthogonal-multilayer tissue-engineered corneal stroma induced by a mechanical collagen microenvironment and transplantation in a rabbit model.
Loss of MED12 Induces Tumor Dormancy in Human Epithelial Ovarian Cancer via Downregulation of EGFR.
Cancer-associated fibroblasts confer cisplatin resistance of tongue cancer via autophagy activation.
UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis.
P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population.
AMPK/NF-κB signaling pathway regulated by ghrelin participates in the regulation of HUVEC and THP1 Inflammation.
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Development of chondrocyte-seeded electrosprayed nanoparticles for repair of articular cartilage defects in rabbits.
GM13133 is a negative regulator in mouse white adipocytes differentiation and drives the characteristics of brown adipocytes.
UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway.
Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity.
Salidroside attenuates hypoxia/reoxygenation-induced human brain vascular smooth muscle cell injury by activating the SIRT1/FOXO3α pathway.
MicroRNA-144 inhibits proliferation by targeting WW domain-containing transcription regulator protein 1 in papillary thyroid cancer.
Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.
Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma.
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
ZEB1 stimulates breast cancer growth by up-regulating hTERT expression.
Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy.
miR-21 modulates prostaglandin signaling and promotes gastric tumorigenesis by targeting 15-PGDH.
Evaluation of vitrification protocol of mouse ovarian tissue by effect of DNA methyltransferase-1 and paternal imprinted growth factor receptor-binding protein 10 on signaling pathways.
Tip60 is associated with resistance to X-ray irradiation in prostate cancer.
Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway.
Influence of patterned titanium coatings on polarization of macrophage and osteogenic differentiation of bone marrow stem cells.
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking.
FAK-ERK activation in cell/matrix adhesion induced by the loss of apolipoprotein E stimulates the malignant progression of ovarian cancer.
Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial Cells.
CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency.
Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats.
Coupling of oxidative stress responses to tricarboxylic acid cycle and prostaglandin E(2) alterations in Caenorhabditis elegans under extremely low-frequency electromagnetic field.
Blocking FGFR4 exerts distinct anti-tumorigenic effects in esophageal squamous cell carcinoma.
Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS.
Inhibition of mTORC2 enhances UVB-induced apoptosis in keratinocytes through a mechanism dependent on the FOXO3a transcriptional target NOXA but independent of TRAIL.
The effect of NR4A1 on APP metabolism and tau phosphorylation.
Low-Intensity Pulsed Ultrasound Treatment Accelerates Angiogenesis by Activating YAP/TAZ in Human Umbilical Vein Endothelial Cells.
Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush.
SFMBT2 positively regulates SOX9 and chondrocyte proliferation.
Aspirin promotes apoptosis and inhibits proliferation by blocking G0/G1 into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway.
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer.
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Elevating ATP-binding cassette transporter G1 improves re-endothelialization function of endothelial progenitor cells via Lyn/Akt/eNOS in diabetic mice.
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
An androgen receptor negatively induced long non-coding RNA ARNILA binding to miR-204 promotes the invasion and metastasis of triple-negative breast cancer.
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.
The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus.
Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Hepatoprotective Effect of Baicalein Against Acetaminophen-Induced Acute Liver Injury in Mice.
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
CD36 plays a critical role in proliferation, migration and tamoxifen-inhibited growth of ER-positive breast cancer cells.
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1.
Atypical Gasdermin D and Mixed Lineage Kinase Domain-like Protein Leakage Aggravates Tetrachlorobenzoquinone-Induced Nod-like Receptor Protein 3 Inflammasome Activation.
Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
Arsenite renal apoptotic effects in chickens co-aggravated by oxidative stress and inflammatory response.
Sulfur dioxide attenuates sepsis-induced cardiac dysfunction via inhibition of NLRP3 inflammasome activation in rats.
Characterization of Divalent Metal Transporter 1 (DMT1) in Brugia malayi suggests an intestinal-associated pathway for iron absorption.
Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms.
Eukaryotic translation initiation factor EIF3H potentiates gastric carcinoma cell proliferation.
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
A novel biphenyl urea compound, TPD7, stimulates apoptosis through modulating Fas signaling and Bcl-2 family proteins in cervical cancer.
Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
MicroRNA-379 suppresses cell proliferation, migration and invasion in nasopharyngeal carcinoma by targeting tumor protein D52.
Disulfiram/copper targets stem cell-like ALDH(+) population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway.
AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.
Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR-196a-5p.
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.
Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Deletion of MBD2 inhibits proliferation of chronic myeloid leukaemia blast phase cells.
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
MEF2A regulates Calpain 3 expression in L6 myoblasts.
Expression of Concern: Knockdown of eIF3d inhibits cell proliferation through G2/M phase arrest in non-small cell lung cancer.
Therapeutic effects of recombinant human S100A6 and soluble receptor for advanced glycation end products(sRAGE) on CCl(4)-induced liver fibrosis in mice.
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Triptolide inhibits Epstein-Barr nuclear antigen 1 expression by increasing sensitivity of mitochondria apoptosis of nasopharyngeal carcinoma cells.
MSX2 Initiates and Accelerates Mesenchymal Stem/Stromal Cell Specification of hPSCs by Regulating TWIST1 and PRAME.
A Scalable and Efficient Bioprocess for Manufacturing Human Pluripotent Stem Cell-Derived Endothelial Cells.
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Ultrastructural Characterization of Corticotropin-Releasing Factor and Neuropeptide Y in the Rat Locus Coeruleus: Anatomical Evidence for Putative Interactions.
MicroRNA-466 (miR-466) functions as a tumor suppressor and prognostic factor in colorectal cancer (CRC).
Exogenous H(2)S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Extract of Euryale ferox Salisb exerts antidepressant effects and regulates autophagy through the adenosine monophosphate-activated protein kinase-UNC-51-like kinase 1 pathway.
TRIM28 promotes cervical cancer growth through the mTOR signaling pathway.
Vitamin D attenuates pressure overload-induced cardiac remodeling and dysfunction in mice.
Gli family zinc finger 1 is associated with endothelin receptor type B in Hirschsprung disease.
Cullin7 promotes epithelial‑mesenchymal transition of esophageal carcinoma via the ERK‑SNAI2 signaling pathway.
Liraglutide inhibits the proliferation and promotes the apoptosis of MCF-7 human breast cancer cells through downregulation of microRNA-27a expression.
Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway.
Downregulation of ubiquitin-specific peptidase 39 suppresses the proliferation and induces the apoptosis of human colorectal cancer cells.
Overexpression of MYC binding protein promotes invasion and migration in gastric cancer.
Sulfur dioxide improves endothelial dysfunction by downregulating the angiotensin II/AT(1)R pathway in D-galactose-induced aging rats.
Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity.
C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation.
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy.
Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer.
Brca1 Is Upregulated by 5-Aza-CdR and Promotes DNA Repair and Cell Survival, and Inhibits Neurite Outgrowth in Rat Retinal Neurons.
MCPIP1 is a positive regulator of type I interferons antiviral activity.
Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization.
Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats.
Astrocytes mediated the nootropic and neurotrophic effects of Sarsasapogenin-AA13 via upregulating brain-derived neurotrophic factor.
Porphyromonas gingivalis and its lipopolysaccharide differently modulate epidermal growth factor-dependent signaling in human gingival epithelial cells.
Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome.
Overexpression of SMOC2 Attenuates the Tumorigenicity of Hepatocellular Carcinoma Cells and Is Associated With a Positive Postoperative Prognosis in Human Hepatocellular Carcinoma.
USP22 Induces Cisplatin Resistance in Lung Adenocarcinoma by Regulating γH2AX-Mediated DNA Damage Repair and Ku70/Bax-Mediated Apoptosis.
MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2.
Macrophages Polarized by Expression of ToxoGRA15(II) Inhibit Growth of Hepatic Carcinoma.
Elevated expression of serine/threonine phosphatase type 5 correlates with malignant proliferation in human osteosarcoma.
MicroRNA-195 Suppresses the Progression of Pancreatic Cancer by Targeting DCLK1.
Bufalin Inhibits Cellular Proliferation and Cancer Stem Cell-Like Phenotypes via Upregulation of MiR-203 in Glioma.
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Effects of Trimetazidine on PDCD4/NF-κB/TNF-α Pathway in Coronary Microembolization.
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity.
Santamarine Inhibits NF-κB Activation and Induces Mitochondrial Apoptosis in A549 Lung Adenocarcinoma Cells via Oxidative Stress.
Intracellular pH Regulates TRAIL-Induced Apoptosis and Necroptosis in Endothelial Cells.
MiR-20a-5p promotes radio-resistance by targeting Rab27B in nasopharyngeal cancer cells.
The Crosstalk between HDPSCs and HUCMSCs on Proliferation and Osteogenic Genes Expression in Coculture System.
Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age.
RETRACTED: LncRNA-AF113014 promotes the expression of Egr2 by interaction with miR-20a to inhibit proliferation of hepatocellular carcinoma cells.
MiR-9-3p augments apoptosis induced by H2O2 through down regulation of Herpud1 in glioma.
Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice.
Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion.
SIRT3 in Neural Stem Cells Attenuates Microglia Activation-Induced Oxidative Stress Injury Through Mitochondrial Pathway.
A modified approach to establish a murine model of hypoxic renal interstitial fibrosis.
Electroacupuncture Alleviates Surgical Trauma-Induced Hypothalamus Pituitary Adrenal Axis Hyperactivity Via microRNA-142.
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
SUN1 silencing inhibits cell growth through G0/G1 phase arrest in lung adenocarcinoma.
Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.
Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Myeloid differentiation factor 88 is up-regulated in epileptic brain and contributes to experimental seizures in rats.
Anterior gradient 2 is induced in cutaneous wound and promotes wound healing through its adhesion domain.
Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells.
iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers.
Puerarin increases the chemosensitivity of hepatocellular carcinoma cells.
The effect of CXCR2 inhibition on seizure activity in the pilocarpine epilepsy mouse model.
Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection.
LINC00052 upregulates EPB41L3 to inhibit migration and invasion of hepatocellular carcinoma by binding miR-452-5p.
Effects of Chinese herbal medicines on the occurrence of diabetic retinopathy in type 2 diabetes patients and protection of ARPE-19 retina cells by inhibiting oxidative stress.
Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer.
RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR.
AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells.
H(2)O(2) attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor.
Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface.
Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina.
HMGA2 plays an important role in Cr (VI)-induced autophagy.
Melatonin inhibits nucleus pulposus (NP) cell proliferation and extracellular matrix (ECM) remodeling via the melatonin membrane receptors mediated PI3K-Akt pathway.
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
Cepharanthine hydrochloride reverses P‑glycoprotein-mediated multidrug resistance in human ovarian carcinoma A2780/Taxol cells by inhibiting the PI3K/Akt signaling pathway.
NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.
Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells.
Angelicin inhibits liver cancer growth in vitro and in vivo.
Human cytomegalovirus miR-US4-5p promotes apoptosis via downregulation of p21-activated kinase 2 in cultured cells.
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
Expression of the tumor suppressor gene p16, and lymph node metastasis in patients with ovarian cancer.
Silencing of TCTN1 inhibits proliferation, induces cell cycle arrest and apoptosis in human thyroid cancer.
Identification of novel direct protein-protein interactions by irradiating living cells with femtosecond UV laser pulses.
Hyperoside alleviates adriamycin-induced podocyte injury via inhibiting mitochondrial fission.
LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells.
Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.
The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells.
Lentivirus-mediated knockdown of M-phase phosphoprotein 8 inhibits proliferation of colon cancer cells.
Carbon monoxide-releasing molecule suppresses inflammatory and osteoclastogenic cytokines in nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via the heme oxygenase-1 pathway.
The Shape of Vesicle-Containing Organelles Is Critical for Their Functions in Vesicle Endocytosis.
MicroRNA‑214 targets Wnt3a to suppress liver cancer cell proliferation.
PHD3 affects gastric cancer progression by negatively regulating HIF1A.
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
CD109 expression is upregulated in penile squamous cell carcinoma.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Correlation between miR-19a inhibition and radiosensitivity in SiHa cervical cancer cells.
Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport.
Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling.
High expression of PDLIM5 facilitates cell tumorigenesis and migration by maintaining AMPK activation in prostate cancer.
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells.
p38β Mitogen-Activated Protein Kinase Signaling Mediates Exenatide-Stimulated Microglial β-Endorphin Expression.
Epigenetic Downregulation of Scn3a Expression by Valproate: a Possible Role in Its Anticonvulsant Activity.
SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells.
A long non-coding RNA lncRNA-PE promotes invasion and epithelial-mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway.
Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial-mesenchymal transition.
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
In vitro study of human mutL homolog 1 hypermethylation in inducing drug resistance of esophageal carcinoma.
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
Effects of autophagy and endocytosis on the activity of matrix metalloproteinase‑2 in human renal proximal tubular cells under hypoxia.
Tetramethylpyrazine-mediated regulation of CXCR4 in retinoblastoma is sensitive to cell density.
Downregulation of calbindin 1, a calcium-binding protein, reduces the proliferation of osteosarcoma cells.
miR-195 inhibits cell proliferation via targeting AEG-1 in hepatocellular carcinoma.
Vps15p regulates the distribution of cup-shaped organelles containing the major eisosome protein Pil1p to the extracellular fraction required for endocytosis of extracellular vesicles carrying metabolic enzymes.
Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming.
Menin enhances c-Myc-mediated transcription to promote cancer progression.
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway.
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations.
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Early growth response 3 inhibits growth of hepatocellular carcinoma cells via upregulation of Fas ligand.
Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents.
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
H(2)S regulates endothelial nitric oxide synthase protein stability by promoting microRNA-455-3p expression.
miR-935 Promotes Liver Cancer Cell Proliferation and Migration by Targeting SOX7.
Fibulin-4 reduces extracellular matrix production and suppresses chondrocyte differentiation via DKK1- mediated canonical Wnt/β-catenin signaling.
Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells.
MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.
A novel antisense long non-coding RNA SATB2-AS1 overexpresses in osteosarcoma and increases cell proliferation and growth.
Long non-coding RNA PVT1 serves as a competing endogenous RNA for miR-186-5p to promote the tumorigenesis and metastasis of hepatocellular carcinoma.
EpCAM and COX‑2 expression are positively correlated in human breast cancer.
Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.
Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.
3'UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma.
The RNA editome of Macaca mulatta and functional characterization of RNA editing in mitochondria.
Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway.
PRL-3 promotes telomere deprotection and chromosomal instability.
Gene expression effects of glucocorticoid and mineralocorticoid receptor agonists and antagonists on normal human skeletal muscle.
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cells.
Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation.
A novel damage mechanism: Contribution of the interaction between necroptosis and ROS to high glucose-induced injury and inflammation in H9c2 cardiac cells.
Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening.
miR-1247-5p functions as a tumor suppressor in human hepatocellular carcinoma by targeting Wnt3.
Porphyromonas gingivalis and its LPS differentially regulate the expression of peptidyl arginine deiminases in human chondrocytes.
Different macrophages equally induce EMT in endometria of adenomyosis and normal.
Rho GDP-dissociation inhibitor α is a potential prognostic biomarker and controls telomere regulation in colorectal cancer.
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
E3 ubiquitin ligase Nedd4 inhibits AP-1 activity and TNF-α production through targeting p38α for polyubiquitination and subsequent degradation.
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Highly expressed NRSN2 is related to malignant phenotype in ovarian cancer.
Ezrin expression is altered in mice lymphatic metastatic hepatocellular carcinoma and subcellular fractions upon Annexin 7 modulation in-vitro.
Hepatic expression of transcription factors affecting developmental regulation of UGT1A1 in the Han Chinese population.
Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138.
Beneficial Effects of a CaMKIIα Inhibitor TatCN21 Peptide in Global Cerebral Ischemia.
Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70.
Bif-1 promotes tumor cell migration and metastasis via Cdc42 expression and activity.
Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy.
Tumor necrosis factor receptor 2 promotes growth of colorectal cancer via the PI3K/AKT signaling pathway.
Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells.
Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes tumorigenesis and metastasis by targeting miR-199a/b-5p in hepatocellular carcinoma.
Interaction of macrophages and endometrial cells induces epithelial-mesenchymal transition-like processes in adenomyosis.
Host Cellular Protein TRAPPC6AΔ Interacts with Influenza A Virus M2 Protein and Regulates Viral Propagation by Modulating M2 Trafficking.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
ISG15 inhibits cancer cell growth and promotes apoptosis.
The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regeneration.
Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer.
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
Elevated systemic glutamic acid level in the non-obese diabetic mouse is Idd linked and induces beta cell apoptosis.
Downregulation of the β1 adrenergic receptor in the myocardium results in insensitivity to metoprolol and reduces blood pressure in spontaneously hypertensive rats.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a.
Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts.
Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model.
The role of alternative polyadenylation in the antiviral innate immune response.
UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy.
Sensitive Approaches for the Assay of the Global Protein Tyrosine Phosphorylation in Complex Samples Using a Mutated SH2 Domain.
miR-138-5p suppresses autophagy in pancreatic cancer by targeting SIRT1.
Histone Modifications Regulate the Developmental Expression of Human Hepatic UDP-Glucuronosyltransferase 1A1.
Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1.
Hydrogen sulfide ameliorated L-NAME-induced hypertensive heart disease by the Akt/eNOS/NO pathway.
Clinical implications of progranulin in gastric cancer and its regulation via a positive feedback loop involving AKT and ERK signaling pathways.
P38/ERK MAPK signaling pathways are involved in the regulation of filaggrin and involucrin by IL‑17.
MACC1 facilitates chemoresistance and cancer stem cell‑like properties of colon cancer cells through the PI3K/AKT signaling pathway.
Baicalin potentiates TRAIL‑induced apoptosis through p38 MAPK activation and intracellular reactive oxygen species production.
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
BTBD7 silencing inhibited epithelial- mesenchymal transition (EMT) via regulating Slug expression in human salivary adenoid cystic carcinoma.
Chlamydia trachomatis plasmid-encoded protein pORF5 protects mitochondrial function by inducing mitophagy and increasing HMGB1 expression.
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
High-intensity interval versus moderate-intensity continuous training: Superior metabolic benefits in diet-induced obesity mice.
Phenotype and Functional Analyses in a Transgenic Mouse Model of Left Ventricular Noncompaction Caused by a DTNA Mutation.
Effects of high-intensity focused ultrasound on cisplatin-resistant human lung adenocarcinoma in vitro and in vivo.
6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon α/β by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells.
Proteomics of acute heart failure in a rat post-myocardial infarction model.
Clinical implications of vasohibin-1 in esophageal carcinoma cells: Inhibition of cell growth and migration.
Protective role of 17β-estradiol on tumor necrosis factor-α-induced apoptosis in human nucleus pulposus cells.
CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation.
The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis.
LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells.
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Epigallocatechin-3-gallate inhibits H(2)O(2)-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Ursolic acid improves podocyte injury caused by high glucose.
Systematic Characterization of Autophagy in Gestational Diabetes Mellitus.
Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.
Downregulation of B-myb promotes senescence via the ROS-mediated p53/p21 pathway, in vascular endothelial cells.
ICT1 knockdown inhibits breast cancer cell growth via induction of cell cycle arrest and apoptosis.
Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer in vitro.
Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism.
G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways.
FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Dendrobium nobile Lindl alkaloid, a novel autophagy inducer, protects against axonal degeneration induced by Aβ(25-35) in hippocampus neurons in vitro.
Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions.
Lentivirus-mediated RNA interference of tripartite motif 68 inhibits the proliferation of colorectal cancer cell lines SW1116 and HCT116 in vitro.
Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways.
Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.
MicroRNA-26a targets MAPK6 to inhibit smooth muscle cell proliferation and vein graft neointimal hyperplasia.
Paper/PMMA Hybrid 3D Cell Culture Microfluidic Platform for the Study of Cellular Crosstalk.
MicroRNA-490 inhibits tumorigenesis and progression in breast cancer.
High expression of Y-box-binding protein 1 correlates with poor prognosis and early recurrence in patients with small invasive lung adenocarcinoma.
Bone marrow derived mesenchymal stem cells alleviated brain injury via down-regulation of interleukin-1β in focal cerebral ischemic rats.
MicroRNA-541 promotes the proliferation of vascular smooth muscle cells by targeting IRF7.
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats.
Madagascine Induces Vasodilatation via Activation of AMPK.
DEC2 suppresses tumor proliferation and metastasis by regulating ERK/NF-κB pathway in gastric cancer.
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Combined effect of 17β-estradiol and resveratrol against apoptosis induced by interleukin-1β in rat nucleus pulposus cells via PI3K/Akt/caspase-3 pathway.
The Downregulation of MicroRNA-10b and its Role in Cervical Cancer.
Identification of Centella asiatica's Effective Ingredients for Inducing the Neuronal Differentiation.
Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy.
High Expression of PTGR1 Promotes NSCLC Cell Growth via Positive Regulation of Cyclin-Dependent Protein Kinase Complex.
Knockdown of USP39 by lentivirus-mediated RNA interference suppresses the growth of oral squamous cell carcinoma.
Expression of microtubule-associated protein TPX2 in human gastric carcinoma and its prognostic significance.
S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory Hepcidin and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway.
Renal Denervation Suppresses the Inducibility of Atrial Fibrillation in a Rabbit Model for Atrial Fibrosis.
Suppression of USP18 Potentiates the Anti-HBV Activity of Interferon Alpha in HepG2.2.15 Cells via JAK/STAT Signaling.
Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme.
The Expression of Bone Morphogenetic Protein 2 and Matrix Metalloproteinase 2 through Retinoic Acid Receptor Beta Induced by All-Trans Retinoic Acid in Cultured ARPE-19 Cells.
Estrogen-related receptor (ERR) γ protects against puromycin aminonucleoside-induced podocyte apoptosis by targeting PI3K/Akt signaling.
Extracellular pH regulates autophagy via the AMPK-ULK1 pathway in rat cardiomyocytes.
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
MYO6 knockdown inhibits the growth and induces the apoptosis of prostate cancer cells by decreasing the phosphorylation of ERK1/2 and PRAS40.
Aberrant adenosine A2A receptor signaling contributes to neurodegeneration and cognitive impairments in a mouse model of synucleinopathy.
The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia.
miR-19a/b modulates lung cancer cells metastasis through suppression of MXD1 expression.
Roles and regulation of autophagy and apoptosis in the remodelling of the lepidopteran midgut epithelium during metamorphosis.
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
PDGF-D/PDGFRβ promotes tongue squamous carcinoma cell (TSCC) progression via activating p38/AKT/ERK/EMT signal pathway.
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
Zfp281 Coordinates Opposing Functions of Tet1 and Tet2 in Pluripotent States.
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis.
The Central Analgesic Mechanism of YM-58483 in Attenuating Neuropathic Pain in Rats.
miR-145 suppresses colorectal cancer cell migration and invasion by targeting an ETS-related gene.
The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.
Overexpression of pro-gastrin releasing peptide promotes the cell proliferation and progression in small cell lung cancer.
Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2.
Polysaccharides from Pleurotus ostreatus alleviate cognitive impairment in a rat model of Alzheimer's disease.
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
Knockdown of Myosin 6 inhibits proliferation of oral squamous cell carcinoma cells.
Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.
Abnormal Expression of FBXL20 in Refractory Epilepsy Patients and a Pilocarpine-Induced Rat Model.
Geldanamycin, an inhibitor of Hsp90, increases paclitaxel-mediated toxicity in ovarian cancer cells through sustained activation of the p38/H2AX axis.
Aliskiren targets multiple systems to alleviate cancer cachexia.
An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice.
A combined modality of carboplatin and photodynamic therapy suppresses epithelial-mesenchymal transition and matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in HEp-2 human laryngeal cancer cells via ROS-mediated inhibition of MEK/ERK signalling pathway.
Induction of Amnion Epithelial Apoptosis by Cortisol via tPA/Plasmin System.
Cardioprotective potential of Dendrobium officinale Kimura et Migo against myocardial ischemia in mice.
miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1.
S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics.
Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling.
The effect of Liuwei Dihuang decoction on PI3K/Akt signaling pathway in liver of type 2 diabetes mellitus (T2DM) rats with insulin resistance.
Neratinib induces ErbB2 ubiquitylation and endocytic degradation via HSP90 dissociation in breast cancer cells.
Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye.
MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration.
Leukemia inhibitory factor promote trophoblast invasion via urokinase-type plasminogen activator receptor in preeclampsia.
shRNA-mediated RPS15A silencing inhibits U937 acute myeloid leukemia cell proliferation and enhances apoptosis.
MicroRNA-335-5p inhibits osteoblast apoptosis induced by high glucose.
Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells.
QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis.
Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device.
The p38 MAPK inhibitor BIRB796 enhances the antitumor effects of VX680 in cervical cancer.
Nuclear accumulation of Yes-Associated Protein (YAP) maintains the survival of doxorubicin-induced senescent cells by promoting survivin expression.
miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma.
Knockdown of prostaglandin reductase 1 (PTGR1) suppresses prostate cancer cell proliferation by inducing cell cycle arrest and apoptosis.
Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway.
Downregulation of hepatic betaine:homocysteine methyltransferase (BHMT) expression in taurine-deficient mice is reversed by taurine supplementation in vivo.
ATP-sensitive K⁺ channels contribute to the protective effects of exogenous hydrogen sulfide against high glucose-induced injury in H9c2 cardiac cells.
Myosin VI contributes to malignant proliferation of human glioma cells.
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Identification and comparative analysis of the oriental river prawn (Macrobrachium nipponense) microRNA expression profile during hypoxia using a deep sequencing approach.
Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy.
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Inhibition of lysyl oxidase by prostaglandin E2 via EP2/EP4 receptors in human amnion fibroblasts: Implications for parturition.
Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells.
EIF3D silencing suppresses renal cell carcinoma tumorigenesis via inducing G2/M arrest through downregulation of Cyclin B1/CDK1 signaling.
Human cytomegalovirus-encoded miR-US4-1 promotes cell apoptosis and benefits discharge of infectious virus particles by targeting QARS.
High expression of DDX20 enhances the proliferation and metastatic potential of prostate cancer cells through the NF-κB pathway.
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Lentivirus-mediated silencing of MPHOSPH8 inhibits MTC proliferation and enhances apoptosis.
Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures.
Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma.
HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer.
The expression and prognostic value of protein tyrosine kinase 6 in early-stage cervical squamous cell cancer.
Autophagy maintains ubiquitination-proteasomal degradation of Sirt3 to limit oxidative stress in K562 leukemia cells.
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation.
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Cyfip1 is downregulated in acute lymphoblastic leukemia and may be a potential biomarker in acute lymphoblastic leukemia.
MicroRNA-503 represses epithelial-mesenchymal transition and inhibits metastasis of osteosarcoma by targeting c-myb.
Aberrant expression of B7-H4 correlates with poor prognosis and suppresses tumor-infiltration of CD8+ T lymphocytes in human cholangiocarcinoma.
The effects of D3R on TLR4 signaling involved in the regulation of METH-mediated mast cells activation.
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
Lentivirus-mediated inhibition of USP39 suppresses the growth of gastric cancer cells via PARP activation.
Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity.
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
The ciliary GTPase Arl13b regulates cell migration and cell cycle progression.
TSH increases synthesis of hepatic ATP-binding cassette subfamily A member 1 in hypercholesterolemia.
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice.
Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression.
Down-regulation of adenylate kinase 5 in temporal lobe epilepsy patients and rat model.
Propofol reduced myocardial contraction of vertebrates partly by mediating the cyclic AMP-dependent protein kinase phosphorylation pathway.
MiR-138-5p promotes TNF-α-induced apoptosis in human intervertebral disc degeneration by targeting SIRT1 through PTEN/PI3K/Akt signaling.
Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Rosuvastatin Alleviates Type 2 Diabetic Atrial Structural and Calcium Channel Remodeling.
Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma.
Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy.
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
Lentivirus‑mediated knockdown of MeCP2 inhibits the growth of colorectal cancer cells in vitro.
siRNA targeting TCTP suppresses osteosarcoma cell growth and induces apoptosis in vitro and in vivo.
Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathway.
Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.
Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor Cells.
Triptolide inhibits transcription of hTERT through down-regulation of transcription factor specificity protein 1 in primary effusion lymphoma cells.
The ERK1/2 pathway participates in the upregulation of the expression of mesenteric artery α1 receptors by intravenous tail injections of mmLDL in mice.
Femtosecond UV-laser pulses to unveil protein-protein interactions in living cells.
Involvement of ICAM-1 in impaired spermatogenesis after busulfan treatment in mice.
Jejunum-ileum circuit procedure improves glucose metabolism in diabetic rats independent of weight loss.
Role of KIF2A in the progression and metastasis of human glioma.
PI3K/Akt signaling pathway is involved in the neurotrophic effect of senegenin.
Clonorchis sinensis lysophospholipase inhibits TGF-β1-induced expression of pro-fibrogenic genes through attenuating the activations of Smad3, JNK2, and ERK1/2 in hepatic stellate cell line LX-2.
Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial β-endorphin expression.
Lentivirus-mediated knockdown of CEP55 suppresses cell proliferation of breast cancer cells.
TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin.
Serological Evaluation of Immunity to the Varicella-Zoster Virus Based on a Novel Competitive Enzyme-Linked Immunosorbent Assay.
ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy.
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology.
Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells.
Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells.
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
RAB18, a protein associated with Warburg Micro syndrome, controls neuronal migration in the developing cerebral cortex.
Low c-Met expression levels are prognostic for and predict the benefits of temozolomide chemotherapy in malignant gliomas.
Characterization of hepatitis E virus infection in tree shrew (Tupaia belangeri chinensis).
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
Knockdown of HNRNPA1 inhibits lung adenocarcinoma cell proliferation through cell cycle arrest at G0/G1 phase.
Down-regulated PLAC8 promotes hepatocellular carcinoma cell proliferation by enhancing PI3K/Akt/GSK3β/Wnt/β-catenin signaling.
Eukaryotic translation initiation factor 3 subunit D overexpression is associated with the occurrence and development of ovarian cancer.
Pim-2 protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced apoptosis via downregulation of Bim expression.
Overexpression of TSPAN8 Promotes Tumor Cell Viability and Proliferation in Nonsmall Cell Lung Cancer.
Alteration of epoxyeicosatrienoic acids in the liver and kidney of cytochrome P450 4F2 transgenic mice.
Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling.
Developmental pattern of the neuronal intermediate filament inaa in the zebrafish retina.
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy.
Knockdown of GGCT inhibits cell proliferation and induces late apoptosis in human gastric cancer.
Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin.
MicroRNA-873 mediates multidrug resistance in ovarian cancer cells by targeting ABCB1.
Activation of autophagy improved the neurologic outcome after cardiopulmonary resuscitation in rats.
Echinacoside Protects Against MPP(+)-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation.
Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells.
Induction of adipose-derived stem cells into Schwann-like cells and observation of Schwann-like cell proliferation.
N-ethylmaleimide‑sensitive factor siRNA inhibits the release of Weibel-Palade bodies in endothelial cells.
Inhibitory effect of RNA-mediated knockdown of zinc finger protein 91 pseudogene on pancreatic cancer cell growth and invasion.
Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK.
Rapid generation of functional hepatocyte-like cells from human adipose-derived stem cells.
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy.
Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats.
CHIP promotes thyroid cancer proliferation via activation of the MAPK and AKT pathways.
Wnt/β-Catenin Signaling Mediated-UCH-L1 Expression in Podocytes of Diabetic Nephropathy.
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
CCBE1 promotes GIST development through enhancing angiogenesis and mediating resistance to imatinib.
Retraction: Expression of peroxisome proliferator-activated receptor gamma (PPARγ) in porcine endometrium and placenta.
PRL-3 promotes gastric cancer migration and invasion through a NF-κB-HIF-1α-miR-210 axis.
Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein.
Tumor-suppressive functions of long-chain acyl-CoA synthetase 4 in gastric cancer.
Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells.
Diagnostic and prognostic value of tissue and circulating levels of Ephrin-A2 in prostate cancer.
SATB2 suppresses gastric cancer cell proliferation and migration.
Epb41l3 suppresses esophageal squamous cell carcinoma invasion and inhibits MMP2 and MMP9 expression.
Lentivirus-Mediated Knockdown of CTHRC1 Inhibits Osteosarcoma Cell Proliferation and Migration.
Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia.
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
HBsAg blocks TYPE I IFN induced up-regulation of A3G through inhibition of STAT3.
MicroRNA-133b targets glutathione S-transferase π expression to increase ovarian cancer cell sensitivity to chemotherapy drugs.
Lentivirus-Mediated knockdown of tectonic family member 1 inhibits medulloblastoma cell proliferation.
MiRNA-15a inhibits proliferation, migration and invasion by targeting TNFAIP1 in human osteosarcoma cells.
PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.
Lentivirus-mediated TPD52L2 depletion inhibits the proliferation of liver cancer cells in vitro.
Levofloxacin increases apoptosis of rat annulus fibrosus cells via the mechanism of upregulating MMP-2 and MMP-13.
Effect of prostaglandin reductase 1 (PTGR1) on gastric carcinoma using lentivirus-mediated system.
MicroRNA-141 inhibits vascular smooth muscle cell proliferation through targeting PAPP-A.
MicroRNA-130a inhibits cell proliferation, invasion and migration in human breast cancer by targeting the RAB5A.
Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells.
PP4R1 accelerates cell growth and proliferation in HepG2 hepatocellular carcinoma.
Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest.
The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis.
Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways.
Anti-fibrotic effects of neferine on carbon tetrachloride-induced hepatic fibrosis in mice.
Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway.
MicroRNA-181a inhibits tumor proliferation, invasiveness, and metastasis and is downregulated in gastric cancer.
Downregulation of Spinal G Protein-Coupled Kinase 2 Abolished the Antiallodynic Effect of Electroacupuncture.
Bone Marrow-Derived Mesenchymal Stem Cells Repair Necrotic Pancreatic Tissue and Promote Angiogenesis by Secreting Cellular Growth Factors Involved in the SDF-1 α /CXCR4 Axis in Rats.
Cardioprotective effect of propofol against oxygen glucose deprivation and reperfusion injury in H9c2 cells.
LPS Induces Occludin Dysregulation in Cerebral Microvascular Endothelial Cells via MAPK Signaling and Augmenting MMP-2 Levels.
SIRT7 Exhibits Oncogenic Potential in Human Ovarian Cancer Cells.
Silencing of Rac3 inhibits proliferation and induces apoptosis of human lung cancer cells.
MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin.
siRNA-mediated knockdown of JUB expression suppresses the proliferation of glioblastoma cells.
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells.
The Cardioprotective Effect of Vitamin E (Alpha-Tocopherol) Is Strongly Related to Age and Gender in Mice.
Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.
A Cell Electrofusion Chip for Somatic Cells Reprogramming.
MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2.
Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome.
Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.
Resveratrol inhibits enterovirus 71 replication and pro-inflammatory cytokine secretion in rhabdosarcoma cells through blocking IKKs/NF-κB signaling pathway.
The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes.
Cytotoxicity of various types of gold-mesoporous silica nanoparticles in human breast cancer cells.
Decreased expression of RPS15A suppresses proliferation of lung cancer cells.
MiR-197 induces Taxol resistance in human ovarian cancer cells by regulating NLK.
PU.1-Regulated Long Noncoding RNA lnc-MC Controls Human Monocyte/Macrophage Differentiation through Interaction with MicroRNA 199a-5p.
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Lentivirus-Mediated Short-Hairpin RNA Targeting Protein Phosphatase 4 Regulatory Subunit 1 Inhibits Growth in Breast Cancer.
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Inhibition of protein phosphatase 5 (PP5) suppresses survival and growth of colorectal cancer cells.
Delivery of Adipose-Derived Stem Cells Attenuates Adipose Tissue Inflammation and Insulin Resistance in Obese Mice Through Remodeling Macrophage Phenotypes.
Lentivirus-Mediated Silencing of Myosin VI Inhibits Proliferation and Cell Cycle Progression in Human Lung Cancer Cells.
A simple method for differentiation of H9 cells into neuroectoderm.
Tectonic‑1 contributes to the growth and migration of prostate cancer cells in vitro.
Downregulation of ubiquitin-associated protein 2-like with a short hairpin RNA inhibits human glioma cell growth in vitro.
Lentivirus-Mediated Knockdown of Myosin VI Inhibits Cell Proliferation of Breast Cancer Cell.
Small nuclear ribonucleoprotein associated polypeptide N accelerates cell proliferation in pancreatic adenocarcinoma.
Lentivirus‑delivered nemo‑like kinase small interfering RNA inhibits laryngeal cancer cell proliferation in vitro.
The Steroid Hormone 20-Hydroxyecdysone Up-regulates Ste-20 Family Serine/Threonine Kinase Hippo to Induce Programmed Cell Death.
Phosphorylation of STAT3 mediates the induction of cyclooxygenase-2 by cortisol in the human amnion at parturition.
Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells.
Critical role of CDK11(p58) in human breast cancer growth and angiogenesis.
BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.
Analysis of the differential secretome of nasopharyngeal carcinoma cell lines CNE-2R and CNE-2.
Claudin 8 Contributes to Malignant Proliferation in Human Osteosarcoma U2OS Cells.
Mechanism of programmed cell death factor 4/nuclear factor-κB signaling pathway in porcine coronary micro-embolization-induced cardiac dysfunction.
Knockdown of myosin VI by lentivirus-mediated short hairpin RNA suppresses proliferation of melanoma.
ZFP36L1 promotes monocyte/macrophage differentiation by repressing CDK6.
Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure.
Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis.
A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1.
Reduction of progesterone, estradiol and hCG secretion by perfluorooctane sulfonate via induction of apoptosis in human placental syncytiotrophoblasts.
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress.
Immunoglobulin-like transcript 4 promotes tumor progression and metastasis and up-regulates VEGF-C expression via ERK signaling pathway in non-small cell lung cancer.
The expression of CXCL13 and its relation to unfavorable clinical characteristics in young breast cancer.
Characterization of phase I metabolism of resibufogenin and evaluation of the metabolic effects on its antitumor activity and toxicity.
Knockdown of tumor protein D52-like 2 induces cell growth inhibition and apoptosis in oral squamous cell carcinoma.
Homolog of allograft inflammatory factor-1 induces macrophage migration during innate immune response in leech.
17β-estradiol protects against apoptosis induced by interleukin-1β in rat nucleus pulposus cells by down-regulating MMP-3 and MMP-13.
Docosahexanoic acid modifies low-density lipoprotein receptor abundance in HepG2 cells via suppression of the LXRα-Idol pathway.
P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury.
Lentivirus mediated silencing of ubiquitin specific peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro.
Analgesic Effect of Intrathecal Administration of Chemokine Receptor CCR2 Antagonist is Related to Change in Spinal NR2B, nNOS, and SIGIRR Expression in Rat with Bone Cancer Pain.
MicroRNA-93 regulates collagen loss by targeting MMP3 in human nucleus pulposus cells.
The effects of PBDE-209 exposure during pregnancy on placental ET-1 and eNOS expression and the birth weight of offspring.
OSM is overexpressed in knee osteoarthritis and Notch signaling is involved in the effects of OSM on MC3T3-E1 cell proliferation and differentiation.
γ-Glutamylcyclotransferase Knockdown Inhibits Growth of Lung Cancer Cells Through G0/G1 Phase Arrest.
A novel Cx50 (GJA8) p.H277Y mutation associated with autosomal dominant congenital cataract identified with targeted next-generation sequencing.
Indomethacin induces apoptosis in the EC109 esophageal cancer cell line by releasing second mitochondria-derived activator of caspase and activating caspase-3.
Advanced glycation end products induce glomerular endothelial cell hyperpermeability by upregulating matrix metalloproteinase activity.
Inhibition of microRNA-25 by tumor necrosis factor α is critical in the modulation of vascular smooth muscle cell proliferation.
Polyphenol-rich extract of Pimenta dioica berries (Allspice) kills breast cancer cells by autophagy and delays growth of triple negative breast cancer in athymic mice.
YY1 regulates melanoma tumorigenesis through a miR-9 ~ RYBP axis.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Impact of a novel homozygous mutation in nicotinamide nucleotide transhydrogenase on mitochondrial DNA integrity in a case of familial glucocorticoid deficiency.
Role of Endoplasmic Reticulum Stress in Brain Damage After Cardiopulmonary Resuscitation in Rats.
Serine/Threonine Protein Phosphatase-5 Accelerates Cell Growth and Migration in Human Glioma.
Knockdown of eIF3d inhibits cell proliferation through G2/M phase arrest in non-small cell lung cancer.
A novel biphenyl urea derivate inhibits the invasion of breast cancer through the modulation of CXCR4.
HSP27 phosphorylation protects against endothelial barrier dysfunction under burn serum challenge.
Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B.
Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.
Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.
miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes.
Employment of digital gene expression profiling to identify potential pathogenic and therapeutic targets of fulminant hepatic failure.
Translation of 5' leaders is pervasive in genes resistant to eIF2 repression.
Potent effects of dioscin against obesity in mice.
Interleukin 7 up-regulates CD95 protein on CD4+ T cells by affecting mRNA alternative splicing: priming for a synergistic effect on HIV-1 reservoir maintenance.
Triptolide inhibits proliferation of Epstein-Barr virus-positive B lymphocytes by down-regulating expression of a viral protein LMP1.
siRNA-mediated knockdown against NUF2 suppresses pancreatic cancer proliferation in vitro and in vivo.
Coumestrol inhibits carotid sinus baroreceptor activity by cAMP/PKA dependent nitric oxide release in anesthetized male rats.
MicroRNA-103a inhibits gastric cancer cell proliferation, migration and invasion by targeting c-Myb.
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma.
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Tumor protein D52-like 2 contributes to proliferation of breast cancer cells.
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Mechanism of action of gypenosides on type 2 diabetes and non-alcoholic fatty liver disease in rats.
Multiple lysines combined in HIV-1 Vif determines the responsiveness to CBF-β.
DNA damage and ER stress contribute to oblongifolin C-induced cell killing in Bax/Bak-deficient cells.
Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis.
Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells.
Effects of atorvastatin on PDCD4/NF-κB/TNF-α signaling pathway during coronary microembolization of miniature pigs.
Growth hormone replacement therapy regulates microRNA-29a and targets involved in insulin resistance.
Ultrasound-targeted microbubble destruction-mediated microRNA-21 transfection regulated PDCD4/NF-κB/TNF-α pathway to prevent coronary microembolization-induced cardiac dysfunction.
MicroRNA-214 suppresses the proliferation of human hepatocellular carcinoma cells by targeting E2F3.
Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma.
Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13.
The midgut of the silkmoth Bombyx mori is able to recycle molecules derived from degeneration of the larval midgut epithelium.
HSF4 promotes G1/S arrest in human lens epithelial cells by stabilizing p53.
PARP-1 promotes autophagy via the AMPK/mTOR pathway in CNE-2 human nasopharyngeal carcinoma cells following ionizing radiation, while inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells.
Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression.
Effects of JIP3 on epileptic seizures: Evidence from temporal lobe epilepsy patients, kainic-induced acute seizures and pentylenetetrazole-induced kindled seizures.
ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer.
Reduced USP39 expression inhibits malignant proliferation of medullary thyroid carcinoma in vitro.
Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish.
Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Expression of RGC32 in human normal and preeclamptic placentas and its role in trophoblast cell invasion and migration.
Tumor protein D52-like 2 accelerates gastric cancer cell proliferation in vitro.
The expression and role of MEKK3 in renal clear cell carcinoma.
Expression of TβR-2, Smad3 and Smad7 in the vaginal anterior wall of postpartum rats with stress urinary incontinence.
Kaiso mainly locates in the nucleus in vivo and binds to methylated, but not hydroxymethylated DNA.
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Inhibition of 11β-HSD2 expression by triclosan via induction of apoptosis in human placental syncytiotrophoblasts.
Potent effects of dioscin against liver fibrosis.
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
Methyl 3,4-dihydroxybenzoate promote rat cortical neurons survival and neurite outgrowth through the adenosine A2a receptor/PI3K/Akt signaling pathway.
miR-367 promotes epithelial-to-mesenchymal transition and invasion of pancreatic ductal adenocarcinoma cells by targeting the Smad7-TGF-β signalling pathway.
Ku80 cooperates with CBP to promote COX-2 expression and tumor growth.
BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs.
Angelica Sinensis polysaccharides stimulated UDP-sugar synthase genes through promoting gene expression of IGF-1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity.
Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery.
The tumor-suppressive microRNA-135b targets c-myc in osteoscarcoma.
Granulocyte colony-stimulating factor reduces fibrosis in a mouse model of chronic pancreatitis.
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.
MicroRNA-33b suppresses migration and invasion by targeting c-Myc in osteosarcoma cells.
MicroRNA-503 acts as a tumor suppressor in osteosarcoma by targeting L1CAM.
Ginsenoside Rb1 prevents H2O2-induced HUVEC senescence by stimulating sirtuin-1 pathway.
Autophagy is involved in the cardioprotection effect of remote limb ischemic postconditioning on myocardial ischemia/reperfusion injury in normal mice, but not diabetic mice.
Expression of annexin A7 and its clinical significance in differentiation and metastasis of gastric carcinoma.
MicroRNA-543 acts as an oncogene by targeting PAQR3 in hepatocellular carcinoma.
Activation of the Nrf2-ARE pathway attenuates hyperglycemia-mediated injuries in mouse podocytes.
Intestinal mucosal barrier is injured by BMP2/4 via activation of NF-κB signals after ischemic reperfusion.
The possible role of the novel cytokines il-35 and il-37 in inflammatory bowel disease.
MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis.
The mitochondrial thioredoxin is required for liver development in zebrafish.
Novel approaches for the identification of nuclear transport receptor substrates.
PARK7 protein translocating into spermatozoa mitochondria in Chinese asthenozoospermia.
Galectin-3 is associated with a poor prognosis in primary hepatocellular carcinoma.
Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α.
Knockdown of ubiquitin associated protein 2-like inhibits the growth and migration of prostate cancer cells.
si-RNA-Mediated Silencing of ADRBK1 Gene Attenuates Breast Cancer Cell Proliferation.
Knockdown of ZFX suppresses renal carcinoma cell growth and induces apoptosis.
Synergistic contribution of SMAD signaling blockade and high localized cell density in the differentiation of neuroectoderm from H9 cells.
A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.
MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes.
Mechanisms for U2AF to define 3' splice sites and regulate alternative splicing in the human genome.
The role of microRNA-133b and its target gene FSCN1 in gastric cancer.
Temporal phosphoproteomics to investigate the mechanotransduction of vascular smooth muscle cells in response to cyclic stretch.
Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.
SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma.
The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation.
Protective effects of dioscin against alcohol-induced liver injury.
Identification of rat respiratory mucosa stem cells and comparison of the early neural differentiation potential with the bone marrow mesenchymal stem cells in vitro.
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis.
MiR-214 promotes the alcohol-induced oxidative stress via down-regulation of glutathione reductase and cytochrome P450 oxidoreductase in liver cells.
The mechanisms of EGFR in the regulation of axon regeneration.
Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway.
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Effects of targeted modulation of miR-762 on expression of the IFITM5 gene in Saos-2 cells.
ZNF16 (HZF1) promotes erythropoiesis and megakaryocytopoiesis via regulation of the c-KIT gene.
CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited.
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
C-type natriuretic peptide attenuates LPS-induced endothelial activation: involvement of p38, Akt, and NF-κB pathways.
[Excessive fluoride inducing calcium overload and apoptosis of ameloblasts].
Ribosomal protein S15A augments human osteosarcoma cell proliferation in vitro.
MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells.
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis.
Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway.
The RNA binding of protein A from Wuhan nodavirus is mediated by mitochondrial membrane lipids.
P-glycoprotein expression in Perna viridis after exposure to Prorocentrum lima, a dinoflagellate producing DSP toxins.
Rapamycin enhances cetuximab cytotoxicity by inhibiting mTOR-mediated drug resistance in mesenchymal hepatoma cells.
miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer.
Inducible metabolic adaptation promotes mesenchymal stem cell therapy for ischemia: a hypoxia-induced and glycogen-based energy prestorage strategy.
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
TAp63 suppress metastasis via miR-133b in colon cancer cells.
Expression and prognostic relevance of MET and phospho-BAD in non-small cell lung cancer.
Coculture of embryonic ventricular myocytes and mouse embryonic stem cell enhance intercellular signaling by upregulation of connexin43.
MiR-138 induces renal carcinoma cell senescence by targeting EZH2 and is downregulated in human clear cell renal cell carcinoma.
All-trans retinoic acid modulates mitogen-activated protein kinase pathway activation in human scleral fibroblasts through retinoic acid receptor beta.
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway.
Mutations in ABCB6 cause dyschromatosis universalis hereditaria.
miR-218 is downregulated and directly targets SH3GL1 in childhood medulloblastoma.
Emodin can induce K562 cells to erythroid differentiation and improve the expression of globin genes.
Clathrin heavy chain 1 is required for spindle assembly and chromosome congression in mouse oocytes.
MicroRNA-124 protects neurons against apoptosis in cerebral ischemic stroke.
The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
Bladder filling and voiding affect umbrella cell tight junction organization and function.
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Negative regulation of lncRNA GAS5 by miR-21.
MicroRNA 23b regulates autophagy associated with radioresistance of pancreatic cancer cells.
PIAS1 negatively modulates virus triggered type I IFN signaling by blocking the DNA binding activity of IRF3.
Induction of pluripotency in mouse somatic cells with lineage specifiers.
Membrane association of Wuhan nodavirus protein A is required for its ability to accumulate genomic RNA1 template.
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage.
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.
MicroRNA-200a promotes anoikis resistance and metastasis by targeting YAP1 in human breast cancer.
The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL.
The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms.
Umbilical cord blood cells regulate endogenous neural stem cell proliferation via hedgehog signaling in hypoxic ischemic neonatal rats.
The tumor-suppressive function of UNC5D and its repressed expression in renal cell carcinoma.
Neuroprotective effect of resveratrol on ischemia/reperfusion injury in rats through TRPC6/CREB pathways.
Effects of sodium hydrosulfide on intestinal mucosal injury in a rat model of cardiac arrest and cardiopulmonary resuscitation.
Methylation of Wnt antagonist genes: a useful prognostic marker for myelodysplastic syndrome.
PRL-3 activates NF-κB signaling pathway by interacting with RAP1.
Emodin regulates apoptotic pathway in human liver cancer cells.
Bifidobacterium infantis-mediated HSV-TK/GCV suicide gene therapy induces both extrinsic and intrinsic apoptosis in a rat model of bladder cancer.
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Protective effect of autophagy inhibition on ischemia-reperfusion-induced injury of N2a cells.
The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.
Neuroprotective effect of Danshensu derivatives as anti-ischaemia agents on SH-SY5Y cells and rat brain.
Cdc42-interacting protein-4 promotes TGF-Β1-induced epithelial-mesenchymal transition and extracellular matrix deposition in renal proximal tubular epithelial cells.
Transcriptional regulation of PES1 expression by c-Jun in colon cancer.
Distribution of bone morphogenetic protein receptors in human scleral fibroblasts cultured in vitro and human sclera.
Alantolactone induces activation of apoptosis in human hepatoma cells.
Total flavonoids from Rosa Laevigata Michx fruit attenuates hydrogen peroxide induced injury in human umbilical vein endothelial cells.
Simvastatin reduces myocardial injury undergoing noncoronary artery cardiac surgery: a randomized controlled trial.
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways.
New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.
Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation.
The 5' untranslated region of Apaf-1 mRNA directs translation under apoptosis conditions via a 5' end-dependent scanning mechanism.
Differential expression profile of MicroRNAs during differentiation of cardiomyocytes exposed to polychlorinated biphenyls.
A single centrifugation method for isolating fat droplets from cells and tissues.
NOK/STYK1 has a strong tendency towards forming aggregates and colocalises with epidermal growth factor receptor in endosomes.
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.
Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death.
A novel taspine derivative, HMQ1611, inhibits breast cancer cell growth via estrogen receptor α and EGF receptor signaling pathways.
Silencing of FABP3 promotes apoptosis and induces mitochondrion impairment in embryonic carcinoma cells.
N-α-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression.
Glycyl-tRNA synthetase specifically binds to the poliovirus IRES to activate translation initiation.
Satb2 is required for dendritic arborization and soma spacing in mouse cerebral cortex.
MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia.
Activation of apoptosis by ethyl acetate fraction of ethanol extract of Dianthus superbus in HepG2 cell line.
MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression.
Differential expression of oxidored nitro domain containing protein 1 (NOR1), in mouse tissues and in normal and cancerous human tissues.
Glutamate attenuates IGF-1 receptor tyrosine phosphorylation in mouse brain: possible significance in ischemic brain damage.
Effects of SASH1 on melanoma cell proliferation and apoptosis in vitro.
Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.
NDR1/STK38 potentiates NF-κB activation by its kinase activity.
Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways.
Sulfated polysaccharide isolated from the sea cucumber Stichopus japonicus promotes neurosphere migration and differentiation via up-regulation of N-cadherin.
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
Eos negatively regulates human γ-globin gene transcription during erythroid differentiation.
miR-125b, a target of CDX2, regulates cell differentiation through repression of the core binding factor in hematopoietic malignancies.
Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells.
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
The expression of a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is under the regulation of the HPG axis.
Biosynthesis and distribution of Lewis X- and Lewis Y-containing glycoproteins in the murine male reproductive system.
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma.
PTOV1 is associated with UCH-L1 and in response to estrogen stimuli during the mouse oocyte development.
Single-walled carbon nanotube induction of rat aortic endothelial cell apoptosis: Reactive oxygen species are involved in the mitochondrial pathway.
Role of Sema4C in TGF-β1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.
17β-Estradiol increased the expression of daintain/AIF-1 in RAW264.7 macrophages.
Combined effects of lapatinib and bortezomib in human epidermal receptor 2 (HER2)-overexpressing breast cancer cells and activity of bortezomib against lapatinib-resistant breast cancer cells.
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation.
RNA interference inhibits hepatitis E virus mRNA accumulation and protein synthesis in vitro.
p,p'-DDE induces testicular apoptosis in prepubertal rats via the Fas/FasL pathway.
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Melatonin protects N2a against ischemia/reperfusion injury through autophagy enhancement.
Toxicity of derivatives from semicarbazide-sensitive amine oxidase-mediated deamination of methylamine against Toxoplasma gondii after infection of differentiated 3T3-L1 cells.
Dual role of Ski in pancreatic cancer cells: tumor-promoting versus metastasis-suppressive function.
Construction of the Vero cell culture system that can produce infectious HCV particles.
Oncoprotein BMI-1 induces the malignant transformation of HaCaT cells.
Radon-induced proteomic profile of lung tissue in rats.
Suppression of survivin expression by short hairpin RNA induces apoptosis in human laryngeal carcinoma cells.
Proteomic alteration in lung tissue of rats exposed to cigarette smoke.
A cytotoxin isolated from Agkistrodon acutus snake venom induces apoptosis via Fas pathway in A549 cells.
Wei S, Wang J, Zhang Z, Fu Y, Zhao L, Bi Y, Li X, Dai S, Zhang C, Zhu W, Min L, Shan B, Zhao L
Research (Washington, D.C.) 2026;9:1070
Research (Washington, D.C.) 2026;9:1070
Lymph Node Metastasis-Associated Spatiotemporal Mapping of the TFF3-Linked Niche in Breast Cancer: Integrating Radiogenomic Signatures with Immune-Ecosystem Remodeling.
Cai D, Zhu C, Huang H, Cao Y, Cai G, Chen Z, Feng J, Zhang W, Mao W, Lai J
Research (Washington, D.C.) 2026;9:1016
Research (Washington, D.C.) 2026;9:1016
Glucocorticoid-dependence and independence of the circadian liver transcriptome.
Maidstone RJ, Hunter AL, Iqbal M, Begley N, Baxter M, Loudon ASI, Rattray M, Ray DW
Npj biological timing and sleep 2026;3:6
Npj biological timing and sleep 2026;3:6
POFUT2 Mediated Fucosylation of JUP Enhances VEGFA Expression to Promote Angiogenesis in Colorectal Cancer.
Zou Y, Yang Y, Xu W, Cao P, Li Z
International journal of medical sciences 2026;23(2):412-427
International journal of medical sciences 2026;23(2):412-427
Tumor-Derived CXCL10 and CCL20 Polarize the Immune Microenvironment in Nasopharyngeal Carcinoma via Competitive Recruitment of Effector T Cells and Tregs.
Zhang B, Yuan X, Meng L, Liu Y, Wang Y, Chen Z, Zeng H, Zhang X, Peng Z, Zhang H, Jiang W
International journal of medical sciences 2026;23(1):26-41
International journal of medical sciences 2026;23(1):26-41
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
Gong K, Song K, Wang H, Li L, Sun X, Sun L, Hao W, Chen ZS, Huang Y
International journal of biological sciences 2026;22(5):2215-2232
International journal of biological sciences 2026;22(5):2215-2232
Parkin Deficiency Impairs ER-Mitochondria Associations and calcium homeostasis via IP3R-Grp75-VDAC1 Complex.
Xue NJ, Liu Y, Lin ZH, Huang WH, Zhang F, Zheng R, Si XL, Gu LY, Fan Y, Pu JL, Zhang BR
International journal of biological sciences 2026;22(2):731-749
International journal of biological sciences 2026;22(2):731-749
Schisandrin B Targets PXR to Enhance Bile Acid Metabolism and Alleviate ANIT-Induced Cholestatic Liver Injury via Dual Pathways.
Zhang Y, Lan H, Yu X, Zhuo L, Zhao B, Liu F, An L, Zhang F, Liu Z, Wang C
International journal of biological sciences 2026;22(1):387-409
International journal of biological sciences 2026;22(1):387-409
Targeting Myeloid FoxO1 Ameliorates Sepsis-induced Intestinal Injury by Modulating Tim4(+) Macrophage Glycolysis.
Ni J, Zhang R, Pu Y, He Y, Hu W, Su L, Hou Y, Dou H
International journal of biological sciences 2026;22(1):239-257
International journal of biological sciences 2026;22(1):239-257
Integrative bioinformatics and experiments identify RIBC2 as a key regulator in the esophageal cancer.
Zheng X, Cui Y, Yao X, Wu Y, Ge Y, Jin Y, Gan J, Yao W, Bi Y, Sun G
PloS one 2026;21(2):e0340850
PloS one 2026;21(2):e0340850
Spatholobus suberectus Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling.
Chen G, Li H, Chen R, Yao Y, Lian G, Bai L, Chen H, Zhang C, Chen G
International journal of nanomedicine 2026;21:585928
International journal of nanomedicine 2026;21:585928
AJUBA: The Master Regulator Bridging EMT and Immune Evasion in Colorectal Cancer.
Shen W, Cui M, Liao X, Xiong Y, Zou B, Zhang X, Shao C
Mediators of inflammation 2026;2026(1):e7828477
Mediators of inflammation 2026;2026(1):e7828477
Hsa_circ_0000313/miR-1224-3p/MKNK2 Axis Modulates CD4(+) T Cells by Activating p38 MAPK Signaling in Myasthenia Gravis.
Li Y, Kong X, Cai H, Tian W, Ren Y, Xu F, Peng S, Niu J, Xin G, Wang J, Zhang H, Wang L
Mediators of inflammation 2026;2026(1):e2877539
Mediators of inflammation 2026;2026(1):e2877539
A Novel MAP3K7 Variant Causing Loss of Function Identified in a Family With Cardiospondylocarpofacial Syndrome: Functional Validation and Molecular Insights.
Zhu T, Shi J, Li J, Zhou T, Fu X, Xu F, Gu C, Wang D, Wu R, Liu L, Shen J, Wang D
Human mutation 2026;2026:8024677
Human mutation 2026;2026:8024677
Multiomics Analysis Identifies Chromosomal Instability-Associated Immune-Related Signatures in Hepatocellular Carcinoma by Integrating Weighted Gene Coexpression Network Analysis (WGCNA) and Machine Learning.
Li Z, Zhong B, Zhang Q, Sun L, Li X, Hu X
Human mutation 2026;2026:6594696
Human mutation 2026;2026:6594696
PAPPA2 c.392G>C Heterozygous Mutation Associates Primary Open-Angle Glaucoma in a Chinese Family.
Wang G, Guo Z, Ren J, Zhang G, Tao H, Liu Y, Zheng S, Zhang X, Wang D, Zhao R, Cui H, Zhu S, Xu H, Duan S, Li H
Human mutation 2026;2026:5591097
Human mutation 2026;2026:5591097
Adipose Mesenchymal Stem Cells Promote Wound Healing by Modulating Expression of SERPINE1 in Dermal Fibroblasts and Keratinocytes.
Liang Y, Sun Q, Sun J, Xu M, Xu J, Yu Y
Stem cells international 2026;2026:5541440
Stem cells international 2026;2026:5541440
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
Shao C, Sun Y, Zhao J, Ju C, Yang T, Liu J, Zhou L, Jia R, Zhao F
Stem cells international 2026;2026:3343152
Stem cells international 2026;2026:3343152
X-Box Binding Protein 1 Regulates Osteogenesis of Periodontal Ligament Cells During Aging by Modulating P53 Signaling Pathway.
Zheng Y, Zhai M, Bai X, Yu K, Li J, Zhang Z
Stem cells international 2026;2026:2846096
Stem cells international 2026;2026:2846096
Gut-Derived Hippuric Acid Alleviates Hepatic Lipid Metabolism via UGDH/FOXK1/CD36 Axis in Obese Mice.
Chen S, Xue J, Shao Y, Liu H, Zhou F, Gu X, Zhou G, Xu T, Wang D, Tang L
Drug design, development and therapy 2026;20:595588
Drug design, development and therapy 2026;20:595588
Enhancing oligodendrocytes generation and myelin renewal by vitamin C mitigate Parkinson-relevant phenotypes in a murine model of Parkinson's disease.
Cui S, Wang S, Liu M, Zou Q, Cai Z, Ma J
Frontiers in cellular neuroscience 2026;20:1761155
Frontiers in cellular neuroscience 2026;20:1761155
A Five-Gene PANoptosis Signature Correlates with Immune Infiltration and Secondary Brain Injury in Intracerebral Hemorrhage.
Chen Z, Zhang X, Deng Z, Luo J, Han C, Weng Y
International journal of general medicine 2026;19:581629
International journal of general medicine 2026;19:581629
Protective Effects of Cyclosporin H Against Sepsis-Induced Acute Kidney Injury via Modulation of Fpr1 Signaling and Inhibiting Pyroptosis.
Feng H, Jiang L, Weng C
Research and reports in urology 2026;18:578231
Research and reports in urology 2026;18:578231
Anjiang formula inhibits PVN microglial activation and lowers blood pressure by targeting RhoA/ROCK2 pathway: a retrospective clinical and experimental study.
Chen X, Chen J, Chen Z, Lian D, Wang J, Wu M, Luo J, Shen A, Chen L
Frontiers in pharmacology 2026;17:1795297
Frontiers in pharmacology 2026;17:1795297
Oncolytic adenovirus encoding a TGF-β inhibitor synergizes with PD-1 blockade to potentiate NK cell cytotoxicity against NSCLC.
Zhu Z, Xu C, Kong X, Zhang S, Lu S, Zhang S, Xu W, Zhang Q, Zhu M
Frontiers in immunology 2026;17:1759236
Frontiers in immunology 2026;17:1759236
3-Hydroxystearic acid promotes cholesterol efflux and attenuates atherosclerosis via the ALKBH5/PAX-8/ABCA1 pathway.
Zhou QY, Liu W, Zhao ZW, Gong D, Ma XF, Tang CK
Frontiers in immunology 2026;17:1750021
Frontiers in immunology 2026;17:1750021
Loss of the translational repressor 4E-BP1 promotes skin carcinogenesis.
Zhou Y, Dou H, Liu Y, Wang J, Ding X, Huang T
Frontiers in pharmacology 2026;17:1742429
Frontiers in pharmacology 2026;17:1742429
Apigenin ameliorates postoperative inflammation and accelerates wound healing in a rat model of perianal abscess by targeting the JAK1/STAT3 pathway in macrophages.
Dai R, Cao L, Ren J, Liu J, Zhu K, Chen P, Yao W, Zhao X, Bao B, Zhang L
Frontiers in immunology 2026;17:1726917
Frontiers in immunology 2026;17:1726917
PLA-THF-PEG nanoparticles Co-encapsulating AV3 and KH3 for synergistic pancreatic cancer therapy via stromal remodeling and metabolic inhibition.
Liu X, Hu Y, Yu J, Xue Y, He X, Jiang F
Frontiers in pharmacology 2026;17:1723694
Frontiers in pharmacology 2026;17:1723694
Wuji Wan ameliorates ulcerative colitis by restoring impaired membrane transport.
Zhang J, Zhang Y, Guo Y, Sun Y, Li Y, Li Q, Chen Y, Wang Y, Yang Q, Zhang M, Weng X, Deng Z
Frontiers in pharmacology 2026;17:1718919
Frontiers in pharmacology 2026;17:1718919
METTL14 modulates the nasopharyngeal carcinoma microenvironment via m(6)A-modified YWHAH identified through single-cell and machine learning analyses.
Liang Z, Zhou Z, Wang J, Shen L, Li Y, Zhu L, Hong G, Li Q, Xiao D, Lin X, Lin T
Frontiers in immunology 2026;17:1717039
Frontiers in immunology 2026;17:1717039
Crocin protects against smoke-induced chronic obstructive pulmonary disease by regulating AKT1.
Zhu Y, Jiang Y, Xu J, Yan S, Ma Z
Frontiers in pharmacology 2026;17:1687752
Frontiers in pharmacology 2026;17:1687752
Unveiling potential diagnostic biomarkers for rheumatoid arthritis through integrated gene expression analysis.
Feng ZW, Yang MK, Jia XD, Yuan F, Guo MG, Chen F, Li W, Yang CF
Frontiers in immunology 2026;17:1645257
Frontiers in immunology 2026;17:1645257
Luteolin mitigates proliferative vitreoretinopathy through inhibition of ERK1/2 signaling and epithelial-mesenchymal transition.
Wu L, Chen M, Chai J, Tang Y, Xu Q
Frontiers in pharmacology 2026;17:1634617
Frontiers in pharmacology 2026;17:1634617
Identification of m1A/m6A/m5C/m7G-related genes and clusters associated with neuropathic pain.
Tan L, Gan X, Lu D, Liang Y, Fu W, Gan Z, Wang K, Tang H, Yang P
Frontiers in neurology 2026;17:1592545
Frontiers in neurology 2026;17:1592545
Splicing factor FUS facilitates the progression of PIT1-lineage PitNETs by upregulating MDM2.
Wang X, Li J, Jiang C, Zhang C, Yuan L, Zhang T, Liu Y, Ma S, Kang P, Li D, Guan X, Chen J, Jia W
Theranostics 2026;16(6):3032-3049
Theranostics 2026;16(6):3032-3049
CD146(+) pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.
Liu W, Duan W, Xia S, Liu Y, Chu H, Liang K, Fang S, Lin M, Wei S, You X, Hu Q, Qi J, Wang Q
Theranostics 2026;16(4):1905-1924
Theranostics 2026;16(4):1905-1924
TM9SF4 acts as a receptor mediating Glaesserella parasuis cytolethal distending toxin-induced cytotoxicity in PK15 cells.
Lei L, Xu S, Yang Z, Pan X, Xu J, Du S, Zhao Q, Huang X, Cao S, Wu R, Wang Y, Yan Q, Wen Y
Frontiers in cellular and infection microbiology 2026;16:1783709
Frontiers in cellular and infection microbiology 2026;16:1783709
Effects of low-serum adaptation on growth and protein expression in stably lactoferrin-overexpressing mammary alveolar cells.
Qiang Z, Cai X, Zhang Z, Wang H, Wang Q, Ji Y, Li G, Su G, Yang L, Qiao W, Zhao J, Chen M, Bai C, Chen L
Frontiers in bioengineering and biotechnology 2026;14:1731548
Frontiers in bioengineering and biotechnology 2026;14:1731548
Functionalized magnetic hydrogel encapsulation of human dental follicle stem cells under a static magnetic field enhances multi-site bone regeneration.
Deng P, Zheng M, Du B, Liu C, Cheng R, Liu C, Wang F, Dong H, Shan Y, Xu Y
Regenerative biomaterials 2026;13:rbag023
Regenerative biomaterials 2026;13:rbag023
Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization.
Li Q, Jiang M, Zhu B, Wei W, Xia L, Huang J, Gao H, Du M
International journal of oncology 2026 May;68(5)
International journal of oncology 2026 May;68(5)
The brain imaging feature-related gene NRP2 drives the malignant progression of glioblastoma through the FAK pathway: a Mendelian randomization study.
Li Y, Que J, Xia Y, Wang L, Zhang P, Cheng Z, Gao B
Translational oncology 2026 May;67:102732
Translational oncology 2026 May;67:102732
Heart-nosed bat alphacoronaviruses use human CEACAM6 to enter cells.
Gallo G, Di Nardo A, Lugano D, Roberts AJ, Kutima BA, Okombo M, Dewantari AK, Buckley FMM, Wright GJ, Nyagwange J, Agwanda B, Graham SC, Bailey D
Nature 2026 May;653(8113):180-189
Nature 2026 May;653(8113):180-189
PRSS23 functions downstream of ZEB1 to promote esophageal squamous cell carcinoma progression by driving M2 polarization of tumor associated macrophages.
Chen W, Chen C, Hu Z, Li F, Peng Y, Zhang M
Molecular and cellular biochemistry 2026 May;481(5):2175-2192
Molecular and cellular biochemistry 2026 May;481(5):2175-2192
The coordinated action of UFMylation and the RQC pathways clears arrested polypeptides at the ER.
Mihailovic M, Anisimova AS, Erte B, Zhan N, Styliara I, Dagdas Y, Karagöz GE
The EMBO journal 2026 May;45(9):3252-3275
The EMBO journal 2026 May;45(9):3252-3275
BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia.
Park J, Kim SH, Park J, Park H, Kim H, Kim DW, Lim C
Leukemia 2026 May;40(5):955-969
Leukemia 2026 May;40(5):955-969
Farnesol Targets the GSTP1/MAPK Axis to Inhibit Trauma-Induced Tendon Heterotopic Ossification.
Deng X, Li T, Li G, Zhu T, Kong Y, Fu B, Li JJ, Chen C, Lei W, Jiang G, Zhang K
Phytotherapy research : PTR 2026 May;40(5):2692-2709
Phytotherapy research : PTR 2026 May;40(5):2692-2709
Periplogenin Suppresses Hepatocarcinogenesis by Inducing Cellular Senescence via the Activating FOXO1/P53 Signaling Pathway.
Wang P, Zhu J, Li W, He Z, Dai X, Shi Y, Xu Z, Wang P, Wang R, Chen J, Liang R, Huang J, Jiang Y, Chen G, Chen H, Xie X
Phytotherapy research : PTR 2026 May;40(5):2588-2603
Phytotherapy research : PTR 2026 May;40(5):2588-2603
Asiatic Acid Ameliorates MNNG-Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis.
Zhou F, Zhu C, Yuan W, Peng W, Xu Q, Yang H, Cao R, Wang B, Wang M, Xu H
Phytotherapy research : PTR 2026 May;40(5):2210-2229
Phytotherapy research : PTR 2026 May;40(5):2210-2229
Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis.
Han Y, Yang S, Zhang J, Wang Y, Zhao X, Liu H
Molecular medicine reports 2026 May;33(5)
Molecular medicine reports 2026 May;33(5)
Downregulation of integrin α3 in ADHD mirrored in mutant mouse model by dopamine-dependent hippocampal AMPAR expression.
Yao X, Chen R, Zhu J, Hou R, Xiang S, Jia T, Gu Y, Wang Z, Hu H, Chen H, Wang H, Feng J, Robbins TW, Wang Y, Higley MJ, Koleske AJ, Xiao X
Molecular psychiatry 2026 May;31(5):2542-2560
Molecular psychiatry 2026 May;31(5):2542-2560
Lipid-trap mass spectrometry identifies lipid-protein interactions in cells.
Paquola A, Benson CE, Desale SE, Ozbalci C, Storck EM, Terry SJ, Rao BD, Nwite KN, Ferrentino F, Eggert US
Nature cell biology 2026 May;28(5):1066-1075
Nature cell biology 2026 May;28(5):1066-1075
NRH attenuates age-related hearing loss by suppressing cochlear ferroptosis and cellular senescence via Sirt3 activation.
Yuan C, Feng C, Ma T, Li S, Liu M, Tang G, Han L, Xing Y, Zhang T
Free radical biology & medicine 2026 May;248:450-468
Free radical biology & medicine 2026 May;248:450-468
ALDH5A1 as a key in osteonecrosis of the femoral head: Insights from bioinformatics and experimental validation.
Ren T, Qin Q, Pang L, Zheng X, Huang J, Meng J, Qiu Y, Li Z, Yao J
Biomedical reports 2026 May;24(5):63
Biomedical reports 2026 May;24(5):63
Detoxification of T-2 toxin in human chondrocytes due to its hydroxylation by carboxylesterases and arylacetamide deacetylase in the liver.
Cheng S, Shi S, Cheng B, Liu C, Yang X, Liu L, Liu H, Wen Y, Tinkov AA, Skalny AV, Jia Y, Zhang F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:116007
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:116007
High-fat diet perturbs hepatic lipid metabolism and impairs colonic autophagy to exacerbate experimental colitis.
Xu T, Shi J, Ji J, Ma C, Li J
3 Biotech 2026 May;16(5):171
3 Biotech 2026 May;16(5):171
High-throughput screened kaempferitrin potentiates trastuzumab efficacy in HER2-positive gastric cancer by targeting Cyclooxygenase-2 to inhibit ERK signaling.
Zhao H, Yang J, Yu H, Liu H, He Q, Li Z, Pan F, Wu L, Shi W, Jiao Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158034
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158034
Bufei Jianspi formula alleviates intestinal epithelial barrier injury by inhibition of calpain 2 in COPD rat.
Wang K, Tao L, Zhang Q, Liu L, Shan B, Zhao P, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158006
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158006
Macrophage Membrane-Cloaked, ROS-Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome.
Li W, Guan Y, Song N, Zhang F, Deng Z, Yin T, Yang Y, Conde J, Jin W, Yin Z
Advanced healthcare materials 2026 May;15(17):e05171
Advanced healthcare materials 2026 May;15(17):e05171
BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer-Associated Fibroblasts Crosstalk.
Shi HZ, Wu MY, Liu JQ, Tian C, Ma L, Zhou XM, Sun ZH, Xu ZY, Zhang RD, Ye SY, Huang LM, Wang Y, Xiong JS, Bu WB, Cheng XF, Sun JF, Chen H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(28):e14590
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(28):e14590
Promotion of DFU Wound Healing via BRG1-COL16A1 Axis in Fibroblasts.
Wang P, Sun J, Wang Y, Ren B, Liu Y, Liu Y, Chen L, Yu L, Dai T, Yu L, Dong Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e16687
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e16687
Cuproptosis and Disulfidptosis Converge to Empower PD-L1 Checkpoint Therapy via Cadict-Induced PD-L1 Translation.
Huang S, Song S, Zhang X, Gao J, Pu R, Dai J, Wu X, Chen L, Li Q, Liu X, Zhou Q, Song M, He W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e15367
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e15367
Ultrasound-assisted extraction optimization of Fructus Tribuli polysaccharides: How stir-frying processing alters structures and enhances antihypertensive efficacy.
Wang S, Sun H, Lv X, Li J, Du D, Guo F, Zhang C
Ultrasonics sonochemistry 2026 May;128:107829
Ultrasonics sonochemistry 2026 May;128:107829
Fluorescence polarization-based discovery of natural RORγ orthosteric inhibitors.
Yu YC, Huang N, Zhao ZH, Bao RF, Xu F, Xu ZQ, Wu YC, Leng XJ, Ma XY, Cao QQ, Sun SL, Zhong H, Li NG
European journal of medicinal chemistry 2026 May 5;309:118778
European journal of medicinal chemistry 2026 May 5;309:118778
Discovery of potent TNIK inhibitors containing a 1H-pyrrolo[2,3-b]pyridine scaffold as promising therapeutics for colorectal cancer.
Niu X, Zhang S, Xu B, Deng W, Zhang X, He H, Shi X, Tong M, Chen J, Qin M
European journal of medicinal chemistry 2026 May 5;309:118717
European journal of medicinal chemistry 2026 May 5;309:118717
tRF-1432 orchestrates RBMS1-IMPDH2 regulatory control to drive purine-dependent chemoresistance in breast cancer.
Dai Y, Wu X, Cheng X, Shang J, Yu Z, Xia Y, Pei S, Kang Y, Jin J, Wang S, Xie H, Cui Y
Cancer letters 2026 May 28;646:218408
Cancer letters 2026 May 28;646:218408
Chaihu-Shugan San ameliorates perimenopausal obesity with depression by coordinately targeting hepatic PGC-1α/CYP8B1/PPARγ signaling and gut barrier integrity.
Chen Q, Liu J, Wang J, Yin T, Wu Y, Zhang T, Yu F
Journal of ethnopharmacology 2026 May 23;363:121407
Journal of ethnopharmacology 2026 May 23;363:121407
Saikosaponin D alleviates chronic prostatitis/chronic pelvic pain syndrome by regulating the NF-κB pathway via lncRNA5682.
Wang X, Zang Z, Zhou Y, Liu Z, Zhang H, Zhang K, Wang Z, Fu Q
Journal of ethnopharmacology 2026 May 23;363:121384
Journal of ethnopharmacology 2026 May 23;363:121384
Tacrolimus-accelerated renal interstitial injury in subtotal nephrectomized rats and its pharmacological modulation by everolimus.
Nakayama Y, Kamikawa S, Masuda S
Toxicology letters 2026 May 15;420:111907
Toxicology letters 2026 May 15;420:111907
Multi-omics analysis and preliminary experimental validation of acetyl tributyl citrate (ATBC) promoting bladder cancer progression via the AKR1B1/EMT axis.
Jie J, Wang Q, Chen Z, Hu C, Lai Z, Ke S, Zhu Y, Li F, Fan Q, Tan W
Environmental pollution (Barking, Essex : 1987) 2026 May 15;397:127970
Environmental pollution (Barking, Essex : 1987) 2026 May 15;397:127970
F-53B exposure accelerates progression from preexisting fatty liver to non-alcoholic steatohepatitis and hepatic fibrosis.
Hu C, Wu L, Zhang Z, Liu Y, Yang H, Zhou J, Wu Y, Wang Q
iScience 2026 May 15;29(5):115675
iScience 2026 May 15;29(5):115675
Glutaredoxin-1 attenuates transactive response DNA-binding protein 43-induced neurotoxicity by suppressing oxidative stress and transactive response DNA-binding protein 43 aggregation.
Lee JM, Bok E, Kim SR, Kim J
Neuroreport 2026 May 13;37(8):319-323
Neuroreport 2026 May 13;37(8):319-323
Inflammation-responsive framework nucleic acids for ulcerative colitis therapy.
Zhang T, Huang J, Chen X, Zhou Y, Chen H, Xiao J, Ma Y, Tong N, Li R, Li W
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114845
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114845
Dual-action nasal spray with mussel protein and xylitol restores epithelial barrier and attenuates type 2 inflammation in allergic rhinitis.
Zhang B, Wang W, Fang P, Wang Y, Xia J, Xu M
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114809
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114809
Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver.
Zhang S, Yan D, Cheng S, Jin J, Cui J, Liu C, Li Y, Qiu F
Journal of ethnopharmacology 2026 May 10;362:121356
Journal of ethnopharmacology 2026 May 10;362:121356
The modified Zuojin formula (SQQT) associates ILC2-linked JAK-2/STAT5/c-Myc cascade and gastric metaplasia regression.
Yang X, Wang Y, Liu S, Ji H, Zhang J, Lv L, Lu M, Wang P, Wang F, Tang X
Journal of ethnopharmacology 2026 May 10;362:121345
Journal of ethnopharmacology 2026 May 10;362:121345
Naringenin inhibits Ferroptosis and ameliorates interstitial cystitis with metabolic syndrome by activating the Nrf2/NQO-1 pathway.
Zhao J, Ju C, Shao C, Sun Y, Yang T, Liu J, Wu D, Li H, Jia R, Zhou L, Zhao F
International immunopharmacology 2026 May 1;176:116485
International immunopharmacology 2026 May 1;176:116485
Grape Seed Proanthocyanins Extract Ameliorates the Neurotoxicity Induced by Fluoride Through mTOR/p70s6k Signaling Pathway in Vivo and in Vitro.
Zhao W, Gong Z, Wang B, Wu Z, Guo Y, Wang S, Zhai H, Zheng X, Yang L
Cell biochemistry and biophysics 2026 Mar;84(1):967-983
Cell biochemistry and biophysics 2026 Mar;84(1):967-983
Cytoskeletal-related genes function as checkpoints for the maintenance of VSMC contractile phenotype and prevent pathological remodeling in arterial diseases.
Liu Y, Zeng L, Cai Q, Zeng Y, Zheng S, Gong X, Zhou L, Tian M, Chen L, Wu G, Zeng C
Journal of advanced research 2026 Mar;81:689-707
Journal of advanced research 2026 Mar;81:689-707
Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers.
Li S, Zhang W, Yang Q, Li S, Zhou X, Wang H, Sun Y, Liu X, Ji C, Zhou J, Nie S, Wu X, Jiao J, Dou L, Hu Q, Jiang F, Xu Q, Dai X, Nan Z, Song X, Zhang D, Zhao W, Wang S, Chu J, Liu L
Journal of advanced research 2026 Mar;81:507-519
Journal of advanced research 2026 Mar;81:507-519
Cadmium targeting MLKL-Drp1 axis to trigger mitochondrial oxidative stress contributes to necroinflammation in rat kidney.
Lian CY, Xia WH, Sun MC, Wan XM, Zhou XL, Wang L
Journal of advanced research 2026 Mar;81:1079-1093
Journal of advanced research 2026 Mar;81:1079-1093
Oncogenic role of talin-1 in glioma: Association with poor prognosis and regulation of the TGF-beta signaling pathway.
Li J, Zhang D, Zhou H, Hou L, Wang Y, Zhang Z, Wang Y, Li X, Yi L, Liu X, Wang Y, Xue X
Translational oncology 2026 Mar;65:102691
Translational oncology 2026 Mar;65:102691
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.
Yang F, Liu D, Hu L, Tan H, Wei Y, Yang R, Huang B, Zou Q, Wu Q, He Y, Mai H, Lan X, Yan Y, Huang Z, Huang X, Fu Z, Deng Z, Huang Q, Yao S, Liang Y
Molecular and cellular endocrinology 2026 Mar;613:112721
Molecular and cellular endocrinology 2026 Mar;613:112721
Concurrent Ferroptosis and Apoptosis in Resveratrol-Treated Glioblastoma Cells: Relevance With NRF2 Downregulation and Oxidative Stress.
Farman A, Zheng X, Wu ML, Hong L, Qian W, Liu J
Cell biology international 2026 Mar;50(3):e70153
Cell biology international 2026 Mar;50(3):e70153
Rg1-R1 attenuates cardiac ischemia/reperfusion-induced endothelial cell injury through activating the ULK1/PGAM5-FUNDC1-mitophagy pathway.
Song X, Deng J, Wang D, Zheng Z, Li C, Li J
Journal of ginseng research 2026 Mar;50(2):100973
Journal of ginseng research 2026 Mar;50(2):100973
The miR-2110/TRAF3 axis is associated with endothelial dysfunction and atherosclerosis in coronary heart disease.
Tran T, Wang ZY, Li PS, Yang Y, Zhang YW, Zhang SM, Dinh P, Le N, Pham T, Huang L, Chen NY, Peng JH, Pan SL
Biochemistry and biophysics reports 2026 Mar;45:102508
Biochemistry and biophysics reports 2026 Mar;45:102508
Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short-Chain Fatty Acids.
Wang A, Miao Z, Huang B, Zeng J, Yuan M, Yan D
Phytotherapy research : PTR 2026 Mar;40(3):1060-1073
Phytotherapy research : PTR 2026 Mar;40(3):1060-1073
Modification of 3D printed porous titanium implants with on-demand delivery of curcumin and stromal cell derived factor-1 for osseointegration improvement.
Ning R, Tang J, Chen L
International journal of biological macromolecules 2026 Mar;350:151037
International journal of biological macromolecules 2026 Mar;350:151037
α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis.
Yue S, Xing H, Du X, Wang Y, Qin R, He J, Yu J, Zhangsun D, Craik DJ, McIntosh JM, Wu Y, Zhu X, Luo S
International journal of biological macromolecules 2026 Mar;349:150933
International journal of biological macromolecules 2026 Mar;349:150933
Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway
.
Tian Y, Xu K, Lu R, Li K, Shao X, Liao Y, Zhao Y, Qiu Z, Dong H, Liu X
Molecular medicine reports 2026 Mar;33(3)
Molecular medicine reports 2026 Mar;33(3)
NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma.
Yan X, He S, Lin Y, Zhang J, Huan J, Chen H, Lu L
Oncology letters 2026 Mar;31(3):114
Oncology letters 2026 Mar;31(3):114
Alpha-Fetoprotein Stimulates Cleavage of Membranal MICA/B on Liver Cancer Cell Lead to Escape Immune Surveillance of Natural Killer Cells.
Li X, Feng S, Wu X, Pan Y, Zhou Y, Liu K, Lin B, Li W, Li M, Zhu M
Journal of cellular and molecular medicine 2026 Mar;30(5):e71076
Journal of cellular and molecular medicine 2026 Mar;30(5):e71076
Acceleration of Lactate Uptake and Utilization Contributes to Neuroprotective Action of FGF21 Involved in Naturally Aging Mice.
Ji K, Wei H, Wang R, Wu Y, Li C, Gao H, Zhao L
Aging cell 2026 Mar;25(3):e70423
Aging cell 2026 Mar;25(3):e70423
The Relationship Between Gut Microbiota-Related Hippocampal Tryptophan Metabolite and Alzheimer's Disease-Like Neurobehavioral Changes Induced by Chronic Inorganic Arsenic Exposure in Rats.
Chen K, Zhao Q, Li S, Wang J, Feng C, Wang L, Yan X, Li B, Zhao Q, Qiu Y
Biological trace element research 2026 Mar;204(3):1781-1795
Biological trace element research 2026 Mar;204(3):1781-1795
OPTN knockout alleviates OVA-induced airway inflammation in a mouse model of asthma.
Zhang Y, Wang Z, Chen J, Wan Y
Molecular immunology 2026 Mar;191:107-113
Molecular immunology 2026 Mar;191:107-113
Novel Ce/Cu-modified black ceramics disrupted mitochondrial dysfunction and tricarboxylic acid cycle to induce cuproptosis in osteosarcoma cells.
Zhang R, Yin X, Xu Z, Yan Q
Biomaterials advances 2026 Mar;180:214576
Biomaterials advances 2026 Mar;180:214576
Characterization and therapy of fertilization failure in murine and human models with HNRNPR mutations.
Gan S, Li Y, Yin L, Yang X, Lou C, Li S, Lin M, Li X, Xu W, Zhou J, Hu P, Yao Z, Yuan Y, Sheng J, Zhang C, Yang W, Li Y, Huang H
EMBO molecular medicine 2026 Mar;18(3):916-942
EMBO molecular medicine 2026 Mar;18(3):916-942
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
Wu J, Cui G, Lin Z, Lin W, Zhang Y, Zhou T, He P, Zhang Y, Yao G
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
A novel proteolysis-targeting chimera strategy targeting multiple immune checkpoints containing ITIMs enhances antitumor immunity.
Qiu YY, Wang ZW, He L, Shi GG, Li ZZ, Ma SX, Yu D, Du HC, Xie F, Zhang C, Zhang YQ, Li M, Li WN
Journal of pharmaceutical analysis 2026 Mar;16(3):101511
Journal of pharmaceutical analysis 2026 Mar;16(3):101511
IL-11 Drives Dermal Fibroblast Activation in Mechanical Stretch-Mediated Skin Expansion.
Liu Y, Khoong YM, Xia W, Xu R, Widjaja AA, Liang H, Luo S, Yang E, Huang X, Zan T
The Journal of investigative dermatology 2026 Mar;146(3):743-757.e9
The Journal of investigative dermatology 2026 Mar;146(3):743-757.e9
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
Wang Q, Ning N, Li Y
Cellular signalling 2026 Mar;139:112339
Cellular signalling 2026 Mar;139:112339
Targeting CDK12 rescues C/EBPβ-mediated platinum and PARP inhibitor resistance in ovarian cancer.
Tan J, Dong W, Wang D, Tu A, Wang Z, Wu X, Zhang F, Zhu Y, Ren L, Ai Y, Feng Y, Zhang J
Cellular signalling 2026 Mar;139:112328
Cellular signalling 2026 Mar;139:112328
tRF-Ser-TGA-011 impedes gastric cancer progression by targeting the MAP3K13/JNK signaling cascade.
Ma Y, Lu H, Zhang L, Zhang Y, Shen J, Xu W, Zhang Y, Yan F
Cellular signalling 2026 Mar;139:112323
Cellular signalling 2026 Mar;139:112323
YTHDF3-TRIM2-P53 axis promotes malignant progression in uveal melanoma (UVM).
Li H, Chen Y, Chen W, Li D, Hao R, Zhang W
Cellular signalling 2026 Mar;139:112316
Cellular signalling 2026 Mar;139:112316
ED-71 prevents glucocorticoid-induced bone loss by inhibiting type H vascular endothelial cell senescence through maintaining mitochondria-associated membrane-mediated calcium homeostasis.
Wang X, Zhang W, Liu T, Rong X, Ren Q, Guan S, Li M
Cellular signalling 2026 Mar;139:112298
Cellular signalling 2026 Mar;139:112298
Nuclear and cytoplasmic USP30-AS1 coordinately regulate breast cancer progression through HnRNPF/p21 and EZH2/c-Myc/p21 axes.
Jiang Y, Liao W, Xin Q, Wang R, Lin G, Li J, Yang Z, Yang S, Zhang H, Li X, Peng Q, Zhang Y, Xie W, Xu N
Genes & diseases 2026 Mar;13(2):101684
Genes & diseases 2026 Mar;13(2):101684
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Xie X, Bi S, Su B, Zhou R, Li X, Yan Z, Zhou X, Wang F, Yu T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Targeting IL27RA Enhances Immunotherapy in Triple-Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment.
Xu J, Long Q, Zhou M, Chen Q, Peng J, Liang Q, Zhang D, Zhou H, Yi W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e16703
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e16703
CYP-mediated metabolic divergence underpins oxoglaucine selectivity: Detoxification in healthy hepatocytes versus mitochondrial apoptosis in hepatocellular carcinoma.
Li P, Zhang H, Chen Y, Lu S, Jiang H, Zeng S, Zhou H
Toxicology in vitro : an international journal published in association with BIBRA 2026 Mar;111:106170
Toxicology in vitro : an international journal published in association with BIBRA 2026 Mar;111:106170
Extracellular tau oligomers exert neurocytotoxicity by triggering mitochondrial dysfunction.
Sun M, Lin J, Li S
Journal of Alzheimer's disease : JAD 2026 Mar;110(1):409-425
Journal of Alzheimer's disease : JAD 2026 Mar;110(1):409-425
Dietary urolithin a improves hepatic antioxidant function and laying performance in aging hens via Nrf2 signaling pathway activation.
Wu L, Zhang Y, Peng L, Ye L, Zhao X
Poultry science 2026 Mar;105(3):106448
Poultry science 2026 Mar;105(3):106448
Silencing progestagen-associated endometrial protein (PAEP) suppresses sorafenib resistance and enhances sorafenib-induced ferroptosis in hepatocellular carcinoma.
Zeng F, Fang C, Wu Y, Yin L, Ge Y, Zhang H, Song C, Cai Y, Xie B, Wu J
Liver research (Beijing, China) 2026 Mar;10(1):82-92
Liver research (Beijing, China) 2026 Mar;10(1):82-92
Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis.
Dong C, Shen R, Pan C, Zhang J, Yu K, Zeng Q
APL bioengineering 2026 Mar;10(1):016107
APL bioengineering 2026 Mar;10(1):016107
Regulation of mitophagy by Fis1 and Fascin1-organized actin.
Nakajima S, Wang TY, Chou TF, Chakrabarty Y, Chan DC
Current biology : CB 2026 Mar 9;36(5):1205-1219.e8
Current biology : CB 2026 Mar 9;36(5):1205-1219.e8
Structural basis of EGF-repeat O-glucosylation by the protein O-glucosyltransferase POGLUT2.
Xia Y, Hu X, Hua Z, Zhang M, Ding X, Shi Y, Ke Y, Li J, Yu H
The Journal of biological chemistry 2026 Mar 9;302(5):111361
The Journal of biological chemistry 2026 Mar 9;302(5):111361
An integrated network pharmacology and proteomics approach reveals the anti-fibrotic effect of Fushen Granule on peritoneal fibrosis.
Yang K, Li J, Wang L, Yu H, Liu X, Gao Z, Wang Z, Zhang L, Yang H
BMC complementary medicine and therapies 2026 Mar 9;26(1)
BMC complementary medicine and therapies 2026 Mar 9;26(1)
Nature-inspired confined cascade enzyme nanoreactors for targeted atherosclerosis therapy.
Wu Y, Xia H, Ding H, Long M, Yan S, Zhang M, Sheng J, Gu N
Signal transduction and targeted therapy 2026 Mar 9;11(1)
Signal transduction and targeted therapy 2026 Mar 9;11(1)
Improve the efficiency of gene silencing through 2'-O-methyl modification of the bases in siRNA terminus.
Kou S, Zhang Y, Qian Y, Ding X, Jin J, Yang Z
Nucleosides, nucleotides & nucleic acids 2026 Mar 9;:1-12
Nucleosides, nucleotides & nucleic acids 2026 Mar 9;:1-12
Microglia Dld-K127 lactylation promotes Parkinson's disease via regulating the metabolism of lactate-pyruvate transformation.
Wang G, Gong G, Yang X, Qian Y, Zhao Y, Li D, Liu M, Xu Z, Zhang F
Journal of advanced research 2026 Mar 9;
Journal of advanced research 2026 Mar 9;
Rejuvenation of THY1(+) nucleus pulposus-derived stem cells promotes intervertebral disc regeneration through FGF10-FGFR1-CREB pathway and mitochondrial fission.
Zhai H, Wang Z, Wang S, Liu Z, Zhao D, Zhang Y, Liu K, Kong X, Meng Q, Gu H, Chen L, Zhang Y, Cheng L
Journal of advanced research 2026 Mar 9;
Journal of advanced research 2026 Mar 9;
Association of lncRNA AGAP11 with prognosis and malignant progression in triple-negative breast cancer.
Fu G, Song J, Wu W, Zhang X, Zhong D
Discover oncology 2026 Mar 8;17(1)
Discover oncology 2026 Mar 8;17(1)
Exercise attenuates high-fat diet-induced liver injury in mice via PPARα pathway and reduction of oxidative stress and inflammation.
Yuan S, Liu J, Wu J, He J, Qiu L
Journal of physiology and biochemistry 2026 Mar 7;82(1)
Journal of physiology and biochemistry 2026 Mar 7;82(1)
Boron Triggers Hepatic Ferroptosis: Unveiling the Dual-Pathogenic Nexus of Oxidative Stress and SLC7A11/GPX4 Dysregulation.
He T, Li Y, Huang J, Su W, Liu S, Quan J, Zhong G, Liu Z, Shi D, Yu W
Animals : an open access journal from MDPI 2026 Mar 6;16(5)
Animals : an open access journal from MDPI 2026 Mar 6;16(5)
Kukoamine B Inhibits EMT in Lung Adenocarcinoma Cells by Regulating Intracellular PD-L1-Mediated p65 Nuclear Translocation.
Hou C, Chen J, Zhang L, Huang Q, Xu J, Zhang R, He Y
Biology 2026 Mar 6;15(5)
Biology 2026 Mar 6;15(5)
Glycogen Hydrogel Loaded with Schistosoma japonicas Peptide SJMHE1 Improves Skin Wound Healing.
Yang Y, Wang S, Jiang Y, Huo L, Zhu W, Zhang X, Zhang Y, Wang X
Biomolecules 2026 Mar 5;16(3)
Biomolecules 2026 Mar 5;16(3)
Gut microbiota dysbiosis and metabolic abnormalities promote oxidative stress and fibrosis in idiopathic pulmonary fibrosis.
Bai B, Li F, Zheng P, Hua C, Li X, Guo D, Zhao W
Scientific reports 2026 Mar 5;16(1)
Scientific reports 2026 Mar 5;16(1)
Palmitoylation Induced Activation of SMAD3 Exacerbates Colitis by Promoting Tissue-resident Memory T Cells Differentiation.
Xu Y, Ji S, Jiang P, Zhao Z, Zhou Q, Su D, Ullah S, Zhao Y, Zou X, Zhang M, Sun J, Xu G, Tang J
Inflammation 2026 Mar 4;49(1)
Inflammation 2026 Mar 4;49(1)
The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis.
Zhang Z, Liu J, Liu Y, Wang L, Li Z, Dong Y, Tian Y, Miao X, Liu Q, Zhang W, Guo H, Xing L, Yang L, Feng X, Liu S
Cells 2026 Mar 4;15(5)
Cells 2026 Mar 4;15(5)
SC2-3, a Marine Nutrient Glycopeptide from Nereis succinea: Alleviating Cyclophosphamide-Induced Immunocompromise in Mice via M1-Type Macrophage Polarization.
Liu Y, Huang Y, Li J, Zhang Y, Wang P
Foods (Basel, Switzerland) 2026 Mar 4;15(5)
Foods (Basel, Switzerland) 2026 Mar 4;15(5)
Maternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities.
Chang H, Zhu X, Shen C, Xu X, Ni Y, Zhang Y, Yan J, Xue J, Li C, Qin Q, Hai K, Hou M, Zhou Z, Ji M, Xu Z
Cell reports 2026 Mar 31;45(4):117211
Cell reports 2026 Mar 31;45(4):117211
TIMP3 Suppresses Oxidative Stress and Ferroptosis of Lens Epithelial Cells in Cataract Through Regulating the Keap1/Nrf2 Pathway.
Duan Z, Zhuo B, Ma D, Hua Z, Han X, Cai L, Yang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71688
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71688
Lentinan mitigates age-related sarcopenia through the promotion of mitochondrial biogenesis.
He Y, Zhang J, Sun X, Fang Y, Fu A, Han X, Zhang J
Food research international (Ottawa, Ont.) 2026 Mar 31;228:118449
Food research international (Ottawa, Ont.) 2026 Mar 31;228:118449
Tumor Radiotherapy-Induced Sympathetic Hyperactivation Orchestrates Rapid Systemic Bone Loss.
Wang C, Kuang S, Sun L, Li Y, Wang G, Sun J, Zhou F, Zhang C
Calcified tissue international 2026 Mar 31;117(1)
Calcified tissue international 2026 Mar 31;117(1)
Ketogenic diet alleviates septic lung injury via microbial gut-lung axis.
Wei M, Yi X, Lin Z, Cai J, Chen S, Zhou F, Cai H, Lu X, Tang J, Shi Y, Cui L, Yang L, Jing X, Zeng Y, Wu R, Shu T, Li Y, Yang F, He Y, Zhao Z, Yang Y, Zhu W, Jiang Q, Zhang W, Tan X, Ma Z, Fan X, Ma W, Li S, Shu W, Wei H, Xiang Z, Gilbert JA, Gong S, Wang Z
Cell metabolism 2026 Mar 3;38(3):493-511.e12
Cell metabolism 2026 Mar 3;38(3):493-511.e12
Pharmacologic and Oncohistone Inhibition of SETD2 Converge on Genomic Instability.
Paparella AT, Boice AG, Park IY, Nishad R, Tripathi D, Nelson SA, Pietryk EW, Jang HJ, Frew IJ, Rathmell WK, Mason FM, Coarfa C, Dere R, Walker CL
Cancers 2026 Mar 3;18(5)
Cancers 2026 Mar 3;18(5)
The Avian Influenza Virus PA Protein Recruits Host RPS27A to Support Viral Replication.
Liu J, Guan F, Song Y, Tian Y, Zhang J, Chen L, Yan A, Yang H, Yang C, Zhang Q
Viruses 2026 Mar 3;18(3)
Viruses 2026 Mar 3;18(3)
The segmented flavivirus ALSV-encoded nucleoprotein VP2 inhibits type I interferon production by targeting RIG-I.
Pan M, Song Z, Wang M, Zhao M, Fang S, Jin F, Tan Q, Xu W, Che L, Liu N, Sui L, Liu Q, Hou Z, Zhao Y
Microbiology spectrum 2026 Mar 3;14(3):e0248425
Microbiology spectrum 2026 Mar 3;14(3):e0248425
Class-I myosin responds to changes in membrane tension during clathrin-mediated endocytosis in human induced pluripotent stem cells.
Smith SL, Zhan T, Li W, De Belly H, Zhang Q, Xu K, Weiner OD, Drubin DG
Proceedings of the National Academy of Sciences of the United States of America 2026 Mar 3;123(9):e2532817123
Proceedings of the National Academy of Sciences of the United States of America 2026 Mar 3;123(9):e2532817123
LncRNA NORAD Enhances Inflammatory Injury in Sepsis-Associated Acute Lung Damage Through miR-150-5p/STAT1-Dependent NF-κB Activation.
Liu H, Chen XX, Wei GH, Li F, Zong HY
The Kaohsiung journal of medical sciences 2026 Mar 3;:e70191
The Kaohsiung journal of medical sciences 2026 Mar 3;:e70191
Research based on serine metabolism indicates mesenchymal stem cells alleviate psoriasis by regulating the PSPH-PINK1-Parkin-NLRP3 pathway in HaCaT.
Lin Q, Ji Y, Yang B, Zhu R, Song P, Zhao RC
Stem cell research & therapy 2026 Mar 28;17(1)
Stem cell research & therapy 2026 Mar 28;17(1)
Obesity-associated metabolic dysregulation aggravates myocardial ischemia-reperfusion injury through Gls2-mediated ferroptosis.
Zhou T, Liu Y, Xiao R, Xie B, Xie W, Qin X, Zhan X, Sun H, Liu D, Qin S, Li C, Sun L, Kang K
European journal of pharmacology 2026 Mar 28;1019:178739
European journal of pharmacology 2026 Mar 28;1019:178739
Bifidobacterium Pseudolongum-Derived Acetate Attenuates Acute Pancreatitis Through GPR43-Mediated Suppression of M1 Macrophage Polarization.
Guan L, Li X, He C, Zheng P, Zou Y, Zhu Q, Li X, Liang J, Yang J, Zhang L, Ye Y, Wan J, Ke H, Liu J, Lu N, Li N, Zhu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 28;:e17642
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 28;:e17642
miR-9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin.
Guo ZZ, Li AY, Xiang TT, Zhang ZH, Deng A, Han Y
The Kaohsiung journal of medical sciences 2026 Mar 27;:e70202
The Kaohsiung journal of medical sciences 2026 Mar 27;:e70202
Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Zhou Y, Liu Q, Wang L, Sun H, Liu Y, Xiang T, Zhu M, Liu X, Liu T, Cong H, Liao L
Advanced healthcare materials 2026 Mar 27;:e05843
Advanced healthcare materials 2026 Mar 27;:e05843
Downregulation of B7-H4 contributes to the synergistic effect of USP2a-targeted/anti-PD-1 combination therapy in EGFR mutant lung cancer.
Sun B, Kong M, Jiang X, Zhu L, Zhang J, Tan L, Wang C, Yuan Z, Chen S, Wang C, Jiang Y, Zhang L
Cancer immunology, immunotherapy : CII 2026 Mar 26;75(4)
Cancer immunology, immunotherapy : CII 2026 Mar 26;75(4)
Discovery of Novel HPK1 Inhibitors via Chemistry-Based Direct-to-Bioassay Screening and SAR Optimization.
Duan Y, He C, Guo Z, Sun K, Zheng T, Lu Y, Zhang B, Zhong W, Ren Y, Liu J, Xu S, Xu J
Journal of medicinal chemistry 2026 Mar 26;69(6):6736-6759
Journal of medicinal chemistry 2026 Mar 26;69(6):6736-6759
Syringin Protects Against Doxorubicin-Induced Cardiotoxicity via Apelinr-Dependent Activation of the Nuclear Factor-Erythroid 2-Related Factor 2/Heme Oxygenase-1 Antioxidant Pathway.
Li Y, Wang T, Shen M, Fu R, Gao X, Wu S, Li C, Lu J, Tu W, Jiang S, Yang G, Wang Z, Li S
Phytotherapy research : PTR 2026 Mar 26;
Phytotherapy research : PTR 2026 Mar 26;
GALNT1 emerges as a potential therapeutic target in breast cancer.
Li J, Zhong P, Li X, Huang R, Zhan Z, Li J, Mao M
Journal of cancer research and clinical oncology 2026 Mar 25;152(3)
Journal of cancer research and clinical oncology 2026 Mar 25;152(3)
Myeloid-Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis.
Zhou M, Xiao Y, Xu Z, Yang C, Li J, Liu Y, Yin P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 25;:e19267
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 25;:e19267
SETDB2-mediated transcriptional repression of IDE in sensory neurons promotes migraine-like pain behaviors in mice.
Zhang Y, Huang Z, Sun Y, Wang S, Tao Y, Lu W, Zhang Y, Jiang D, Ge J, Chen G, Jin X, Ji F, Wang Y, Yu Y, Zhang Y, Tao J
Cell reports 2026 Mar 24;45(4):117201
Cell reports 2026 Mar 24;45(4):117201
Modeling spastic paraplegia 4 with corticospinal motor neuron-enriched cortical organoids reveals genotype-phenotype and HDAC6-targetable pathology.
Mohan N, Ramakrishnan S, Sun X, Sun Y, Connors T, Chai V, Piermarini E, Baas PW, Cai J, Liu M, Qiang L
Cell reports 2026 Mar 24;45(3):117036
Cell reports 2026 Mar 24;45(3):117036
Targeted inhibition of Nrf2 potentiates antitumor immunity and enhances the efficacy of immunotherapy in hepatocellular carcinoma.
Zhu Y, Liu M, Fan X, Xu Y, Diao X, Bi J, Wan X, Assaraf YG, Kwok HF, Chen L
Journal for immunotherapy of cancer 2026 Mar 24;14(3)
Journal for immunotherapy of cancer 2026 Mar 24;14(3)
tRF-3005a regulates exon skipping of SPAG4 by interacting with RALY to drive gastric cancer progression.
Cui H, Yuan Y, Yin Y, Gao R, Liu Z, Peng L, Wang J, Wang Z, Song T, Liu J
Cell death discovery 2026 Mar 24;12(1)
Cell death discovery 2026 Mar 24;12(1)
Matrix Stiffness Modulates Fibroblast Paracrine Signaling to Enhance Autophagy in Keratinocytes: Implications for Wound Healing.
Chen Y, Gao X, Liu Y, Li W, Cai X
ACS omega 2026 Mar 24;11(11):17605-17616
ACS omega 2026 Mar 24;11(11):17605-17616
Visinin-like protein 1 disrupts calcium homeostasis and promotes atrial fibrillation in human and rodent models.
Xiong K, Wang G, Li D, Shao B, Chen Z, Zou Q, Zhang X, Dong Y, Zhao X, Yuan Y, Xu H, Liu Y, Liang D, Wang L, Zhou B, Dong N, Xie D, Chen YH
Signal transduction and targeted therapy 2026 Mar 23;11(1)
Signal transduction and targeted therapy 2026 Mar 23;11(1)
Investigation of the effects and underlying mechanisms of adenylate kinase 1 on inosine monophosphate deposition in Beijing-You chickens.
Hou J, Zhang Y, Zhu L, Qi X, Wang X, Lin Z, Xiao L, Long C, Dou J, Xu Y, Sheng X
Poultry science 2026 Mar 23;105(6):106828
Poultry science 2026 Mar 23;105(6):106828
Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Attenuate Secondary Brain Injury After Intracerebral Hemorrhage in Rats by Modulating the SIRT6/Notch1/NF-κB Signaling.
Xu W, Lu Y
Applied biochemistry and biotechnology 2026 Mar 23;
Applied biochemistry and biotechnology 2026 Mar 23;
Human Umbilical Cord Mesenchymal Stem Cells Protect Against Steroid-Induced Osteonecrosis of the Femoral Head Through Hippo Pathway.
Xing H, Cai W, Chen J, Xu H, Zhang Y, Zhong C, Zhou J, Peng H
Biomedicines 2026 Mar 22;14(3)
Biomedicines 2026 Mar 22;14(3)
Ephrin-A4 ligand promotes gastric cancer cell epithelial-mesenchymal transition via the PI3K/AKT signaling pathway.
Huang C, Li M, Hong JJ, Mo SY, Kuang JJ, Li JZ, Huang JA
Discover oncology 2026 Mar 21;17(1)
Discover oncology 2026 Mar 21;17(1)
VISTA promotes ovarian cancer progression through activation of NF-κB pathway and tumor microenvironment reprogramming.
Liu S, Zhou Q, Ji F, Zhu T, Ding B, Xu J, Zhang T, Lin H, Shen Y
Journal of ovarian research 2026 Mar 20;19(1)
Journal of ovarian research 2026 Mar 20;19(1)
Thioredoxin protects against diabetic hearing loss by regulating TOMM22 mediated mitochondrial autophagy in hair cells and inhibiting microglial M1 polarization.
Zhong S, Xu M, Wang Q, Wang S, Li X, Guo Y, Kong H
Scientific reports 2026 Mar 20;16(1)
Scientific reports 2026 Mar 20;16(1)
LncRNA H19 overexpression protects against acute kidney injury after cardiopulmonary bypass via activating Pink1/Parkin-mediated mitophagy.
Zhang M, Liu M, Wang T, Du Y, Chen Y, Bai Y, Zhang Y, Xue D, Ji B, Wang G
Chinese medical journal 2026 Mar 20;139(6):880-890
Chinese medical journal 2026 Mar 20;139(6):880-890
Mechanotherapeutic Potential of Survivin in Glioblastoma.
Inserra G, Balghonaim S, Jong J, Drewes R, Santo BA, Tumenbayar BI, Pham K, Babatunde S, Tomaszewski JE, Ignatowski TA, Zhao R, Lim J, Kim S, Siddiqui AH, Das BC, Tutino VM, Bae Y
bioRxiv : the preprint server for biology 2026 Mar 20;
bioRxiv : the preprint server for biology 2026 Mar 20;
UBA1 promotes cardiac hypertrophy by suppressing autophagy via targeting ATG5 for ubiquitination.
Lin QY, Yu WJ, Li JX, Jiang WX, Liu SJ, Bi HL, Li HH
Cell communication and signaling : CCS 2026 Mar 2;24(1)
Cell communication and signaling : CCS 2026 Mar 2;24(1)
Combined Multi-Omics Analysis Reveals the Potential Role of Methionine in Regulating the Proliferation, Differentiation, and Lipid Deposition of Yak Intramuscular Preadipocytes.
Wu X, Li J, Peng T, Fu J, Zhong J, Shi H, Wang H
Animals : an open access journal from MDPI 2026 Mar 2;16(5)
Animals : an open access journal from MDPI 2026 Mar 2;16(5)
Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains.
Agius SC, Boudes M, Healy E, Kim Y, Chang YC, Murray M, Manent J, Rientjes J, Lai Z, Nixon S, Homman-Ludiye J, Levina V, McGlinn E, Davidovich C
Molecular cell 2026 Mar 19;86(6):1032-1045.e10
Molecular cell 2026 Mar 19;86(6):1032-1045.e10
Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors.
Wang Q, Chen Z, Zhang G, Yang J, Hu R, Yao T, Zeng C, Zhang S, Jiang W, Zhu S, Wang Y
Science (New York, N.Y.) 2026 Mar 19;391(6791):eadu7686
Science (New York, N.Y.) 2026 Mar 19;391(6791):eadu7686
Decoding microglial metabolic cell death and PANoptosis hub genes in subacute phase of traumatic brain injury: a multi-omics and experimental validation study.
Wu Z, Yang BY, Lai JQ, Lin SH, Lin L, Chen JL, Pan JX, Ruan YX, Chen XR
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
PCBP2 mediates MTUS1 degradation through 3'-UTR binding to restrict pyroptosis and augment malignant progression in esophageal squamous cell carcinoma.
Jiang C, Lu Q, Wang A, Chen H, Yao L
Esophagus : official journal of the Japan Esophageal Society 2026 Mar 19;
Esophagus : official journal of the Japan Esophageal Society 2026 Mar 19;
Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma.
Chen Y, Li X, Luo C, Lin G, Zhou X, Wen Z, Su H, Meng W, Chen C, Lu J, Luo X, Jiang D, Liu H, Ning Z, Chen Y, Tam PK, Pan X
Journal of advanced research 2026 Mar 19;
Journal of advanced research 2026 Mar 19;
Zhen-Wu-Tang ameliorates uremic cardiomyopathy via targeting the kidney-heart inflammatory axis and suppressing CCL2/CCR2-mediated macrophage activation.
Xu Y, Cai J, Fan YM, Qi LW, Zhang L
Chinese medicine 2026 Mar 18;21(1)
Chinese medicine 2026 Mar 18;21(1)
5-HMF inhibits glucocorticoid-induced osteoporosis through the VEGFR2/PI3K/AKT pathway.
Liu S, Fang F, Jiang Y
Scientific reports 2026 Mar 18;16(1)
Scientific reports 2026 Mar 18;16(1)
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Zhan Y, Zhang Z, Zhang Z, Lin M, Liu H, Abulimiti D, Aihemaiti S, Kan Y, Tan J, Chen X, Tao S
Journal of nanobiotechnology 2026 Mar 17;24(1)
Journal of nanobiotechnology 2026 Mar 17;24(1)
CRP Deficiency Rescues Periodontitis-Induced Hippocampal Neurogenesis Impairment by Suppressing OPC-Derived BMP4 Signaling in Rats.
Li L, Deng P, Hou S, Xia X, Zhao W, Zhu X, Zhang Y, Wang C, Xu L, Song J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 17;:e16199
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 17;:e16199
Exploration of the therapeutic potential of magnoflorine against osteoarthritis progression using network pharmacology and in vitro validation.
Wang C, Cui L, Tantai M, Feng G, Cai Z, Feng Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 17;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 17;
Electroacupuncture mitigates lung injury, increases endogenous antioxidant levels and modulates Nrf2 signaling in a rat model of chronic obstructive pulmonary disease.
Tian Y, Zhang L, Zhao P, Liu X, Jin F, Liu Y, Li J
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2026 Mar 16;:9645284261424261
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2026 Mar 16;:9645284261424261
Increased Expression of Connexin 43 Promotes Wnt/β-Catenin Signaling and the Progression of Temporomandibular Joint Osteoarthritis.
Cai S, Yang X, Chen Z, Chen S, Chen L, Cai J, Cai J, Zou Y, Xu L, Wang H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71623
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71623
Glycine alleviates the intestinal epithelial barrier damage induced by imidacloprid via promoting metabolic detoxification.
Cheng W, Wang Y, Li Y, Zhao G
Ecotoxicology and environmental safety 2026 Mar 15;313:120002
Ecotoxicology and environmental safety 2026 Mar 15;313:120002
Shenqi Granules Enhance Recovery from Myocardial Ischemia-Reperfusion Injury by Downregulating MMP9 and ADH1C.
Liu HX, Shi XL, Zhou SY, Li YC, Lin DY, Tan PY, Zhou ZC, Li YW, Li HF, Wen SY
Pharmaceuticals (Basel, Switzerland) 2026 Mar 13;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Mar 13;19(3)
Fasting-induced physiological remodeling alleviated fatty liver in laying hens through regulating hepatic lipid metabolism.
Gong Y, Zeng Q, Geng X, Zhang J, Kang X, Tian Y, Jiang R
Poultry science 2026 Mar 13;105(6):106775
Poultry science 2026 Mar 13;105(6):106775
Programmable genome editing in human cells using RNA-guided bridge recombinases.
Pelea O, Tálas A, Carrera JF, Mathis N, van de Venn L, Yeh CD, Kulcsár PI, Marquart KF, Weber Y, Gerecke SE, Harvey-Seutcheu IF, Mailänder D, Pfleiderer MM, Chanez C, Corn JE, Schwank G, Jinek M
Science (New York, N.Y.) 2026 Mar 12;391(6790):eadz1884
Science (New York, N.Y.) 2026 Mar 12;391(6790):eadz1884
Synergistic Anti-Tumor Activity of LRPPRC Inhibition and Dasatinib Through Dual Oxidative Phosphorylation Disruption.
Chen J, Gao L, Liang Y, Zhou W, Wang Y, Wang X, Fang X, Shao X
Pharmaceuticals (Basel, Switzerland) 2026 Mar 12;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Mar 12;19(3)
Protein Modifications and Metabolic Alterations in the Rat Striatum Following Oil Mist Particulate Matter Exposure Revealed via Untargeted Metabolomics and Phosphoproteomics.
Nie H, Liu X, Shi Y, Liu H, Lai W, Li K, Tian L, Xi Z, Lin B
Toxics 2026 Mar 12;14(3)
Toxics 2026 Mar 12;14(3)
NRF2 deficiency impairs proliferation and survival of chicken primordial germ cells via oxidative stress, mitochondrial dysfunction and apoptosis.
Niu YJ, Yuan G, Ren W, Wu J, Liu G, Zou M, Wang X, Diao Y, Zhang N, Li G, Han W, Cui XS, Chen G, Li B
Poultry science 2026 Mar 12;105(6):106765
Poultry science 2026 Mar 12;105(6):106765
PHF23-Related Prognostic Signature Modulates Immune Microenvironment and Promotes Tumor Malignancy in Glioma.
Zhao G, Wang X, Yang P, Feng P, Dai J, Niu L, Yuan G, Pan Y
International journal of molecular sciences 2026 Mar 11;27(6)
International journal of molecular sciences 2026 Mar 11;27(6)
Shared molecular signatures between atrial fibrillation and chronic obstructive pulmonary disease: an integrated bioinformatic analysis with experimental validation.
Zhou W, Tang Q, Chen D, Chen J, Shi L, Luo F, Yan F, Mao Y, Lu H, Zhou X, Chen Z, Li W
BMC medical genomics 2026 Mar 11;19(1)
BMC medical genomics 2026 Mar 11;19(1)
Declined RTN3 stabilizes DHCR7 to induce cholesterol-dependent tumor progression and MEK inhibitors insensitivity in thyroid cancer.
Ren A, Feng N, Yang T, Tang Z, Liu H, Li Y, Hu Q, Xi Z, Zhu J, Zhou J, Ming J, Liu N, Huang T, Xu M
Cell death & disease 2026 Mar 11;17(1)
Cell death & disease 2026 Mar 11;17(1)
Biological valorization of methane and nitrogen gas-derived ammonia via methanotrophic bacteria for gut-beneficial nutrients.
Gao Z, Liu Y, Jiao S, Fu R, Chen Y, Zhang C, Shen X, Yang G, Yang S, Wang X, Shi L, Fei Q
Nature communications 2026 Mar 11;17(1)
Nature communications 2026 Mar 11;17(1)
BEX2 influences the MCL1-Hedgehog signaling axis to regulate the potential of stemness characterization in colorectal cancer.
Qian Y, Wei J, Bian Y, Tan Y, Fang Y, Chen L, Jiang K, Fu D, Ge X, Ling T, Xiao Q, Ding K, Hu Y
Cancer biology & medicine 2026 Mar 10;23(2):276-93
Cancer biology & medicine 2026 Mar 10;23(2):276-93
Congener-resolved hazard identification of ginkgolic acids as emerging natural contaminants.
Bai J, Liu H, Zhao M, Yan X, Hua L, Zhang M, Chen H, Zhou K, Liu Y
Journal of hazardous materials 2026 Mar 1;505:141479
Journal of hazardous materials 2026 Mar 1;505:141479
Puerariae Lobatae Radix-Gastrodiae Rhizoma ameliorates nitroglycerin-induced chronic migraine by modulating p38 MAPK/CREB signaling pathway in the prefrontal cortex-thalamus neural circuit.
Wang Z, Zhu T, Ren K, Ouyang H, Pan Q, Feng Y, Yang S
Journal of ethnopharmacology 2026 Mar 1;358:121043
Journal of ethnopharmacology 2026 Mar 1;358:121043
Aspartame exacerbates cerebral ischemia-reperfusion injury via mitochondrial dysfunction and ERK/CREB1 pathway suppression.
Bai Y, Feng J, Wu XY, Yao ZS, Liu YT, Li YH, Lu GD, Xue K
Ecotoxicology and environmental safety 2026 Mar 1;312:119938
Ecotoxicology and environmental safety 2026 Mar 1;312:119938
High fluoride exposure disrupts gut microbiota and induces intestinal barrier damage via RhoA/ROCK-mediated cytoskeletal remodeling.
Wang D, Xin J, Lai C, Sun N, Yang Y, He Y, Duan L, Luo J, He Y, Zhang Y, Zhang Y, Wang H, Zeng D, Bai Y, Ni X
Ecotoxicology and environmental safety 2026 Mar 1;312:119898
Ecotoxicology and environmental safety 2026 Mar 1;312:119898
Paeoniflorin mitigates myocardial hypertrophy by regulating mitophagy and ferroptosis mediated by mitochondria-associated AMPK-Parkin-ACSL4 pathway.
Wang Y, Lin S, Liu J, Hu S, Zeng J, Wang M, Li X, He Y, Ren S, Lyu Y, Jia W, Zhao Y, Lin Y
Free radical biology & medicine 2026 Mar 1;245:98-114
Free radical biology & medicine 2026 Mar 1;245:98-114
Hyperacetylation escalates myocardial susceptibility to ischemia reperfusion injury by mediating mitochondrial supercomplexes assembly in T2DM.
Deng Y, Yang W, Yang J, Ji L, Xie M, Tang K, He Q, Hu G, Shangguan W, Jiang C, Li T
Redox biology 2026 Jun;93:104163
Redox biology 2026 Jun;93:104163
Butyrate protects against Klebsiella pneumoniae-induced oxidative stress in alveolar macrophages via p62-Keap1-Nrf2 pathway.
Meng B, Li H, Tang M, Zhu J, Yao R, Xu Y, Zhang Q, Zhu R, Guo Y, Xu Y, Shu Y, Yu L, Li Y, Yang Y, Liu Y, Wu T, Li J
Redox biology 2026 Jun;93:104156
Redox biology 2026 Jun;93:104156
Synaptojanin-2-binding protein ameliorates oxidative stress, neuroinflammation and depression-like behaviors via SYNJ2/PIP(2)/IP(3) signaling pathway.
Wang W, Chen X, Li Y, Wang C, Chang M, Guo R, Wei P, Xu Z, Yu S
Redox biology 2026 Jun;93:104154
Redox biology 2026 Jun;93:104154
Increased Glycogenin-Exposed Residual Glycogen in Lysosomes Is the Early Pathological Finding in Asymptomatic Pompe Disease.
Shi Y, Zhang N, Sun H, Wang Y, Zhao D, Wen B, Yan C, Zhao Y, Li D
Muscle & nerve 2026 Jun;73(6):1172-1181
Muscle & nerve 2026 Jun;73(6):1172-1181
Deciphering IFN signaling in gastric cancer: A single-cell and bulk transcriptomic integration reveals CXCR4 as a key immunomodulator and prognostic determinant.
Song J, Wu F, Wang Y, Chen Q, Zhang Y, Yu H, Chen Y, Jian J
Translational oncology 2026 Jun;68:102778
Translational oncology 2026 Jun;68:102778
CBFA2T3 as a Key Prognostic Biomarker in Lung Adenocarcinoma: Insights from Comprehensive Analysis and Validation.
Xiao J, Luo K, Liu M, Zhao H, Cai Y, Gui Y, Zhang H
Biochemical genetics 2026 Jun;64(3):3827-3851
Biochemical genetics 2026 Jun;64(3):3827-3851
Estradiol promotes trophoblasts syncytization by upregulating ESR2/SP1 transcription factor-mediated poFUT2 expression.
Li Y, Lei Y, Chen Y, Wang L, Wang Y, Wang W, Wang J, Liu S
Molecular and cellular endocrinology 2026 Jun;616:112757
Molecular and cellular endocrinology 2026 Jun;616:112757
3D-MSCs apoptotic bodies-integrated conductive hydrogel mitigates spinal cord injury via immunoregulation and alleviating neuronal pyroptosis.
Zhang J, Xiang L, Cai X, Geng Y, Wu Y, Shi J, Zhang H, Hu X, Jiang X, Zhu P, Shu Y, Miao R, Zhao J, Zhu J, Li Z, Wang X, Xiao J, Zhou K, Yang L, Qi J
Bioactive materials 2026 Jun;60:704-723
Bioactive materials 2026 Jun;60:704-723
Multi-omics and AI-guided discovery and validation of sisomicin as a COPA-targeting agent for pathological scar inhibition.
Li P, Luo Z, Ali M, Li J, Qi F
Burns : journal of the International Society for Burn Injuries 2026 Jun;52(5):108015
Burns : journal of the International Society for Burn Injuries 2026 Jun;52(5):108015
Ophiopogonin B inhibits triple-negative breast cancer progression via suppressing PTP1B and regulating the PI3K/Akt pathway.
Cheng Y, Luo X, Lin L, Xu Y, Zhao S
Toxicology and applied pharmacology 2026 Jun;511:117787
Toxicology and applied pharmacology 2026 Jun;511:117787
Hepatotoxicity Mechanisms of Sirolimus and Everolimus Unveiled Through Metabolomics and Transcriptomics Analysis.
Zhang Z, Tang Y, Xing R, Liao W, Qiu T, Zhou J, Zhang X, Gong X, Lan Y, Xiang S, Chen S, Ji Y
Journal of applied toxicology : JAT 2026 Jun;46(6):2050-2064
Journal of applied toxicology : JAT 2026 Jun;46(6):2050-2064
Class Effect of SGLT2 Inhibitors Against Doxorubicin-Induced Cardiotoxicity via Regulating Adenosine Kinase Mediated-Cardiac Oxidative Stress.
Yan J, Lin K, Dai S, Zhang Y, Zheng R, Shi S, Tang Z, Lai X, Huang W, Su L
Cardiovascular drugs and therapy 2026 Jun;40(3):971-985
Cardiovascular drugs and therapy 2026 Jun;40(3):971-985
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Xu Y, Zhang Y, Sun Z, Gong J, Shen Q, Meng H, Liu X, Chen J, Hao Y, Xu Z, Ma K, Ma L, Guo K, Pan X, Fu X, Zhang C
Materials today. Bio 2026 Jun;38:103117
Materials today. Bio 2026 Jun;38:103117
Integrated pan-cancer profiling and experimental validation identify CCDC59 as a key driver and therapeutic biomarker in liver hepatocellular carcinoma.
Li K, Wan D, Liang X, Yao L, Li J, Liu N, Zhu M, Wang H, Liang F
Pathology, research and practice 2026 Jun;282:156451
Pathology, research and practice 2026 Jun;282:156451
Alpha-ketoglutarate enhances the proliferation and steroidogenic capacities of Tan sheep granulosa cells through autophagy pathway regulation.
Wang J, Wang L, Zhao M, Min S, Yan Y, He J, Song H, Liu X, Chen Q
The Journal of steroid biochemistry and molecular biology 2026 Jun;260:106991
The Journal of steroid biochemistry and molecular biology 2026 Jun;260:106991
Ferroptosis mediates retinal damage caused by the combined effects of sleep deprivation and light damage.
Zou Y, Zhang Y, Peng W, Cai Y, Li Y
Free radical biology & medicine 2026 Jun;249:548-562
Free radical biology & medicine 2026 Jun;249:548-562
Aldh3a1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to amyotrophic lateral sclerosis progression.
Li A, Dong L, Li X, Yi J, Wu JY, Ma J, Zhou J
Free radical biology & medicine 2026 Jun;249:469-488
Free radical biology & medicine 2026 Jun;249:469-488
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
Guo Q, Wang S, Zhong Z, Zhou L, Xia X
Free radical biology & medicine 2026 Jun;249:273-291
Free radical biology & medicine 2026 Jun;249:273-291
Expression of IMD-CBM peptide induces the autophagic degradation of CAV1 (caveolin 1) to inhibit LDL transcytosis and retard diabetic atherosclerosis.
Wang L, Jia X, Bai X, Zhao Y, Cheng W, Shu M, Shu Y, Zhang L, Wang R, Jin S
Autophagy 2026 Jun;22(6):1273-1286
Autophagy 2026 Jun;22(6):1273-1286
Sympathetic overactivity-induced type H endothelial cell senescence contributes to the impairment of vascularized osteogenesis by PKM2-mediated glycolysis in preclinical stages of Alzheimer's mice.
Zhang W, Liu T, Rong X, Liu H, Li M
Bone 2026 Jun;207:117859
Bone 2026 Jun;207:117859
EGR2 affects mixed stroke repair through BNIP3L-mediated microglial mitophagy.
Zhang X, Zhang B, Shi C, Kampan N, Treebupachatsakul W, Pantan R, Narakornsak S, Phatsara M
IBRO neuroscience reports 2026 Jun;20:577-586
IBRO neuroscience reports 2026 Jun;20:577-586
Revisiting the NETs-CYBB-p38 MAPK axis in bronchiectasis: The underlying oxidative injury mechanism.
Zheng S, Tang J, Wu X, Qing C, Jiang Y, Lu W, Bao C, Hong K, Luo J, Kong J
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168236
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168236
Identification of RUNX1 as a Biomarker for Right Ventricular Remodeling in Pulmonary Arterial Hypertension Using WGCNA.
Chen W, Peng M, Chen Y, Luo J, Chen J, Qiu H, Li J
Pulmonary circulation 2026 Jun;16(2):e70297
Pulmonary circulation 2026 Jun;16(2):e70297
Momordin Ic targets SREBP1 to disrupt lipid homeostasis and trigger synergistic apoptosis-ferroptosis in triple-negative breast cancer.
Cheng Y, Shi YZ, Zheng JY, Liu YB, Chen YT, Bao JX, He XY, Chen JQ, Li Q, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158190
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158190
Brusatol derivative ameliorates rheumatoid arthritis and atherosclerosis with associated suppression of mitochondrial fission.
Ma R, Liu J, Yang S, Chen G, Ren J, Zhang C, Chen X, Zhao Y, Zhang J, Yin C, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158171
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158171
Tannic acid inhibits viral replication by disrupting nucleocapsid condensation.
Pan J, Jiang SZ, Zhu Y, Li XW, Yu LB, Wang Z, Shen BL, Luo RB, Fan LJ, Yu Y, Qian BS, Wang ZJ, Liu Y, Cai H, Xue W, Xia T, Han QY, Wang K, Xu X, He XH, Chen Y, Gao Y, Li AL, Li T, Zhang R, Zhao M, Zhou T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158151
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158151
Isobavachalcone exerts anti-gastric cancer effects by targeting dihydroorotate dehydrogenase to induce ROS release and activating the STING pathway.
Kuang Y, Shao Y, Chen J, Dai C, Nomura S, Wang F, Chen J, He Y, Xiao X, Zhang C, Feng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158126
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158126
Pterostilbene inhibits ferritinophagy-mediated ferroptosis via the NRF2/NCOA4/FTH1 axis and alleviates intervertebral disc degeneration through nanoliposomal delivery.
Song Z, Yan M, Lv X, Zhang S, Kou H, Han H, Wang Z, Chen Y, Shi L, Shao Z, Hu B, Chen S, Liu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158051
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158051
A novel METTL3 inhibitor nimbolide ameliorates osteoporosis via orchestrating osteoclastogenesis in an m6A-dependent manner.
Cai C, Zhang Z, Zhao X, Yang C, Huang X, Tang C, Qiu H, Yang S, Zhang Y, Hu X, Zuo R, Zhang C, Chen Y, Chu T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158048
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158048
Adhesion molecule with Ig-like domain 1 regulates stability of carotid plaque via TGFβ/Smad signaling pathway by interaction with TGFRII.
Hu X, Li X, Chen J, Li Y, Zhao Z, Yin X, Duan S, Wang B
Cellular signalling 2026 Jun;142:112412
Cellular signalling 2026 Jun;142:112412
Exploring the potential of heterocyclic-containing tail approach in the development of novel covalent inhibitors dual-targeting EGFR and HER-2: design, synthesis and biological evaluation.
Hao S, Yan JH, Wang R, Ge GH, Si MC, Niu YF, Cai ZH, Zheng WX, Zhao CG, Li X, Cai S, Zhang TJ, Meng FH
Bioorganic & medicinal chemistry 2026 Jun;137:118637
Bioorganic & medicinal chemistry 2026 Jun;137:118637
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
Zhao Q, Zhang HJ, Han MM, Abiti J, Dong YJ, Wang JN, Lu JT, Wang W, Zhang X, Geng SL, Qiu LL, Wang XY, Hua ZC, Wang TY, Jia YL
Synthetic and systems biotechnology 2026 Jun;12:197-208
Synthetic and systems biotechnology 2026 Jun;12:197-208
Liraglutide prevents lupus-associated diffuse alveolar hemorrhage via inhibiting lymphocyte infiltration and promoting macrophage M2 polarization.
Jiang L, He L, Li D, Luo X, Yang M, Wu H, Long H
Journal of translational autoimmunity 2026 Jun;12:100349
Journal of translational autoimmunity 2026 Jun;12:100349
SiO(2) dust induces the transformation of lung fibroblasts to myofibroblasts by activating the S1P-RhoA-YAP signaling pathway.
Zhang H, Huang F, Guan L, Zeng M
Toxicology in vitro : an international journal published in association with BIBRA 2026 Jun;114:106229
Toxicology in vitro : an international journal published in association with BIBRA 2026 Jun;114:106229
Helicobacter pylori infection promotes gastric carcinogenesis by inducing macrophage M2 polarization through the miR-146a-5p/TRAF6 signaling pathway.
Ju F, Fang Y, Liu J, Qian Y
Journal of the science of food and agriculture 2026 Jun;106(8):4877-4889
Journal of the science of food and agriculture 2026 Jun;106(8):4877-4889
Therapeutic mechanism of Changyong Decoction in suppressing colorectal cancer progression and inducing ferroptosis via the PIEZO1-PI3K/AKT signaling axis.
Han M, Shi S, Guan Z, Ma W, Wang X, Jiang H, Man S
Tissue & cell 2026 Jun;100:103379
Tissue & cell 2026 Jun;100:103379
Simiaoyong'an decoction alleviates atherosclerosis by inhibiting adipose tissue inflammation through PPARγ activation: Integrating network pharmacology, molecular docking, and experimental validation.
Shao R, Xu X, Wang X, Sun K, Zhang Q, Wei D, Yang Y, Yang X, Lou L, Wu A, Nie B
Journal of ethnopharmacology 2026 Jun 28;365:121553
Journal of ethnopharmacology 2026 Jun 28;365:121553
Structural characterization of a fructan from Kalimeris indica and its efficacy in accelerating wound healing.
Zhu L, Hou X, Lingling G, Liu K, Sun Y, Wang G
Carbohydrate polymers 2026 Jun 15;382:125271
Carbohydrate polymers 2026 Jun 15;382:125271
A sulfated manno-glucuronan ameliorates β-cell dysfunction in type 2 diabetes by targeting ALDH1A3.
Zhang W, Zhang F, Zou X, Wu N, He S, Lu L, Xu C, Xu W, Jin W, Zhou J
Carbohydrate polymers 2026 Jun 15;382:125227
Carbohydrate polymers 2026 Jun 15;382:125227
Identification of blood-absorbed components of Qingkui Yuyang decoction and its mechanistic roles in ulcerative colitis based on UPLC-Q-Exactive Orbitrap-MS/MS and network pharmacology.
Chen Y, Liu L, Wei Y, Zhang Q, Wang Y
Journal of pharmaceutical and biomedical analysis 2026 Jun 15;273:117408
Journal of pharmaceutical and biomedical analysis 2026 Jun 15;273:117408
Ultrasound-guided HUC-MSCs transplantation alleviates neuropathic pain in CCI rats: a mechanistic study based on microglia/macrophage polarization and the NLRP3 inflammasome.
Xu X, Qiu Y, Fan C, Chen Y, Huang S, Lin L, Wang H, Lai Y, Lai Z, Zhang L
International immunopharmacology 2026 Jun 15;179:116590
International immunopharmacology 2026 Jun 15;179:116590
Dimethyl bisphenolate inhibits ovarian cancer growth by regulating the PI3K/AKT/mTOR signaling pathway.
Liu M, Liu Y, Xue P, Chen R, Zhang H, Hao M, Wang Z, Zhang X, Xu L, Li R, An J, Qu G, Song S, Cao Q
Bioorganic chemistry 2026 Jun 15;174:109769
Bioorganic chemistry 2026 Jun 15;174:109769
Design, synthesis, and biological evaluation of novel hydrophobic tag-based degraders targeting JNK1.
Huang Y, Chi M, Zhang Y, Cai W, Huang W, Ren S, Gu W, Yuan Y, Hou S, Ma L, Chen X
Bioorganic chemistry 2026 Jun 15;174:109756
Bioorganic chemistry 2026 Jun 15;174:109756
Epigenetic reprogramming by organic arsenic CZ2 elicits potent antitumor responses in DLBCL through TMS1 restoration.
Mei W, Zhang M, Zhang D
Bioorganic chemistry 2026 Jun 15;174:109734
Bioorganic chemistry 2026 Jun 15;174:109734
Tetramethylpyrazine mitigates ER-stress-driven ATF4/CHOP apoptosis to protect dopaminergic neurons in cellular and MPTP models of Parkinson's disease.
Zhan S, Wen S, Wu L, Zhang X, Liu J, Zhang G, Liu H
Neuropharmacology 2026 Jun 1;290:110899
Neuropharmacology 2026 Jun 1;290:110899
Beneficial effects of electro-acupuncture treatment in photothrombotic ischemia model rats by remodeling neurovascular unit.
Li Z, Xiao Y, Zhou S, Lam M, Ding Y, Lin R, Yang M, Liang S, Tao J
Brain research bulletin 2026 Jun 1;239:111858
Brain research bulletin 2026 Jun 1;239:111858
High-throughput RNA sequencing identifies hub genes and anti-inflammatory effects of β-caryophyllene in cerebral ischemia-reperfusion via p38MAPK/NF-κB modulation.
Liu J, Li Z, Wen J, Liu S, Ji J, Yang J, Wang S, Wang Y, Liu H
Brain research bulletin 2026 Jun 1;239:111857
Brain research bulletin 2026 Jun 1;239:111857
Ginkgolide B alleviates cerebral ischemia-reperfusion injury by antagonizing TRIM45 to reduce microglia-mediated neuronal damage.
Lv Z, Ji Z, Chen J, Long T, Niu H, Fu P, Lu M, Hao X, Yang Y
Brain research bulletin 2026 Jun 1;239:111854
Brain research bulletin 2026 Jun 1;239:111854
Hippocampal AIM2 inflammasome regulate seizure and cognitive impairment in mice with temporal lobe epilepsy.
Liu L, Liang SY, Zhu MX, Wang J, Sun Z, Zhang X, Wang Y, Sun Y
Neurobiology of disease 2026 Jun 1;223:107392
Neurobiology of disease 2026 Jun 1;223:107392
Spinal cord injury-derived exosomes exacerbate damage: miR-155-5p mediates inflammatory responses.
Fang Y, Chen W, Zhang Y, Yang Y, Wang S, Pei M, Zhou Y, Lin S, He H
Neural regeneration research 2026 Jun 1;21(6):2514-2522
Neural regeneration research 2026 Jun 1;21(6):2514-2522
Hydrogen sulfide ameliorates peritoneal fibrosis: inhibition of high mobility group box-1 expression to block the activation of the transforming growth factor-beta/Smad3 pathway.
Liu L, Huang W, Ming J, Cai F, Wang H, Lai X, Guo Z
Medical gas research 2026 Jun 1;16(2):103-109
Medical gas research 2026 Jun 1;16(2):103-109
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
Wu W, Cheng Z, Shi P, Gao H, Chen X, Wu W, Yu Z, Yang C, Zhang Y
Bioactive materials 2026 Jul;61:555-576
Bioactive materials 2026 Jul;61:555-576
Mitochondria-targeting iridium(III) complex enhances anticancer activity via PDK inhibition and energy metabolism disruption.
Xu S, Xu N, Fang H, Zhu Z, Su Y, Su Z
Journal of inorganic biochemistry 2026 Jul;280:113317
Journal of inorganic biochemistry 2026 Jul;280:113317
Porcine-derived amelogenin P148 in a layer-by-layer chitosan/hyaluronic acid coating for enhanced implant osseointegration.
Wang C, Tao P, Cheng Y, Zhao P, Zeng Z, Bai Q, Kong L, Dong Y, Wang Z
Colloids and surfaces. B, Biointerfaces 2026 Jul;263:115573
Colloids and surfaces. B, Biointerfaces 2026 Jul;263:115573
Bisphenol A exposure disrupts the circadian clock system and impairs glycolipid metabolic function in mice liver.
Dong H, Ding W, Xiao B, Li C, Jiang H, Yang W, Li D, Li C, Zhang H, Gao D, Wang A, Jin Y, Chen H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jul;213:116100
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jul;213:116100
From palmitoylation to cholesterol metabolism: The hidden mechanism of lung tumorigenesis.
Shen L, Zhang H, Li Y, Duan J, Zhang Y, Qu Y, Liu Y, Ye B, Zhou S, Zheng H, Luo C, Zeng K, Wang G, Dong X, Fang C
Cellular signalling 2026 Jul;143:112497
Cellular signalling 2026 Jul;143:112497
The mechanism of depression and anxiety in adulthood after experiencing early adverse experiences: A new two-hit model of depression.
Gong Z, Yang J, Wang Y, Liang W, Yue G
Journal of affective disorders 2026 Jul 15;405:121529
Journal of affective disorders 2026 Jul 15;405:121529
Protective effects of the ethyl acetate fraction from Madeng'ai on lipopolysaccharide-induced acute lung injury in mice: Insights from integrated multi-omics analysis.
Zhang Z, Zhu T, Cao L, Wang Y, Xing XL, Zhang Z
Journal of ethnopharmacology 2026 Jul 15;366:121650
Journal of ethnopharmacology 2026 Jul 15;366:121650
Methyl 3-chloroasterric acid exerted anti-neuroinflammatory and antidepressant effects through the downregulation of P2Y1R.
Zhang Y, Sun M, Zhang Z, Jia Y, Xiao H, Xu X, Pan X, Li Z
International immunopharmacology 2026 Jul 15;181:116689
International immunopharmacology 2026 Jul 15;181:116689
Characterization of a polysaccharide from Rhodobryum giganteum and its activation effects on TLR4/PI3K-Akt/IκBα pathway.
Geng JM, Zhu PF, Xu LS, Liu JL, Yang ZQ, Yang ZY, Jin Q, Liu L
Carbohydrate polymers 2026 Jul 1;383:125319
Carbohydrate polymers 2026 Jul 1;383:125319
The role of the IL-33/ST2/MAPK signalling pathway in macrophage polarisation and endometrial fibrosis.
Li G, Xu F, Luo S, Jin Y, Yuan L, Yang X, Xuan T, Liu D
International immunopharmacology 2026 Jul 1;180:116743
International immunopharmacology 2026 Jul 1;180:116743
Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation.
Yang T, Lu F, Kang Y, Wang L, Li M, Xu W, Bai S, Yu Y, Shi Y, Qin H
International immunopharmacology 2026 Jul 1;180:116726
International immunopharmacology 2026 Jul 1;180:116726
MG53 protects against septic cardiac dysfunction by ubiquitinating ATF2.
Tian M, Shi Y, Gong X, Tan W, Guo X, Chen Y, Yang P, Ren H, Cai Q, Ma J, Zeng C, Wu G
Journal of advanced research 2026 Jan;79:263-275
Journal of advanced research 2026 Jan;79:263-275
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation.
Qu Z, Ding Y, Zhang L, Sun J, Wang T, Zhuang C
Free radical research 2026 Jan;60(1):1-15
Free radical research 2026 Jan;60(1):1-15
Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach.
Jiang SZ, Yu LB, Shen B, Pan J, Li XW, Luo RB, Fan LJ, Qian BS, Zhu Y, Wang Z, Liu Y, Li T, Zhang XR, Yu Y, Xue W, Xia T, Cai H, Han QY, Wang K, Xu X, Zhang R, Zhang XM, Li AL, Zhou T, Gao Y, Zhao M, Li T
Fundamental research 2026 Jan;6(1):535-547
Fundamental research 2026 Jan;6(1):535-547
Single-Nucleus Transcriptomics Uncovers Xaf1-Driven PANoptosis as a Therapeutic Target in Aminoglycoside-Induced Hearing Loss.
Wang X, Xiao H, Wu J, Lin Y, Ao Y, Ye Z, Tan X, Kong F, Chen X, Chai R, Zhang S
Cell proliferation 2026 Jan;59(1):e70081
Cell proliferation 2026 Jan;59(1):e70081
YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice.
Cen J, Yu X, Wang Z, Liu W, Xu J, Fang Q, Gao F, Cao Y, Liu H
Cell proliferation 2026 Jan;59(1):e70079
Cell proliferation 2026 Jan;59(1):e70079
From Cells to Animals: Connexin43 Suppression Enhances Autophagic Flux to Restore Odontogenesis in Inflamed Dental Pulp.
Hu P, Chen Y, Long P, Zhang A, Lan X, He Y, Li G, Li S
International endodontic journal 2026 Jan;59(1):134-152
International endodontic journal 2026 Jan;59(1):134-152
METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner.
Wang Y, Tian Y, Yao G
International journal of molecular medicine 2026 Jan;57(1)
International journal of molecular medicine 2026 Jan;57(1)
S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition.
Liao X, Xu Y, Zhou H, Yi Q, Dong S, Tan B
Oncology reports 2026 Jan;55(1)
Oncology reports 2026 Jan;55(1)
GATA3-NLRP1 Axis Inhibits Hepatocellular Carcinoma Progression Through the Hedgehog Signaling.
Sun D, Sun X, Zhang J, Wang X, Liu L, Xie J, Song H
Cell biology international 2026 Jan;50(1):e70116
Cell biology international 2026 Jan;50(1):e70116
The oncogenic role of NSUN2 in lung adenocarcinoma by stabilizing CCT5 mRNA via a YBX1-dependent m5C modification.
Li M, Du N, Tang P
Molecular and cellular biochemistry 2026 Jan;481(1):231-243
Molecular and cellular biochemistry 2026 Jan;481(1):231-243
Multimerin-1 modulates macrophage M2 polarization and enhances tumor cell stemness in glioblastoma.
Huang C, Yu XB, Zhou YZ, Zhang XB, Dong CM, Bao WQ
Neurological research 2026 Jan;48(1):66-81
Neurological research 2026 Jan;48(1):66-81
ALYREF condensation stabilizes m(5)C-modified PARP10 mRNA and promotes PI3K-AKT signaling in ovarian cancer.
Zhao H, Wei Q, Luo Z, Liu X, Yang C, Chen N, Wang Y, Luo X, Zuo X, Luo Q, Yang Y, Zhou Y, Liu J, Zhang T, Yang D, Long Y, Mobet Y, Xu J, Wang W, Liu T, Yi P
The EMBO journal 2026 Jan;45(2):471-503
The EMBO journal 2026 Jan;45(2):471-503
Complement C3a Suppresses Spinal Cord Neural Stem Cell Activation by Inhibiting UCHL1 via the NF-κB p65/Nrf2 Pathway.
Ding L, Li X, Guo Y, Zhou FQ, Deng DYB
Neuroscience bulletin 2026 Jan;42(1):153-174
Neuroscience bulletin 2026 Jan;42(1):153-174
Lopinavir/ritonavir induces hepatotoxicity in HepG2 cells through inhibition of the Nrf2 pathway, resulting in oxidative stress, endoplasmic reticulum stress, and cell cycle arrest.
Zhou W, Dan Wang, Tu J, Li J, Xu J, Tan W, Mo D, Liang P, Guo Y, Hu M, Ye L
Toxicology letters 2026 Jan;415:111798
Toxicology letters 2026 Jan;415:111798
The role of FOXO1/PPARγ in atrazine-induced hepatic lipid metabolism disorders.
Yingchao H, Haoyan M, Zengchen W, Haotang Z, Tong L, Ying Q, Xiaotong W, Yuezhu Z
Toxicology letters 2026 Jan;415:111797
Toxicology letters 2026 Jan;415:111797
Piperine Inhibits the Immune Checkpoint CD47 to Enhance Immunity Against Pancreatic Cancer.
He X, Lu Y, Zhang H, Lin B, Lu H, Yu Z, Li Y, Xi Q, Zhang R
Phytotherapy research : PTR 2026 Jan;40(1):194-212
Phytotherapy research : PTR 2026 Jan;40(1):194-212
Structural characterization and multi-omics analysis of novel Saposhnikovia divaricata (Turcz.) Schischk acidic heteropolysaccharide alleviating acute liver injury.
Sun X, Zhang T, Zhu W, Jiang X, Wang S, Zhao Y, Bian X
International journal of biological macromolecules 2026 Jan;339(Pt 1):149819
International journal of biological macromolecules 2026 Jan;339(Pt 1):149819
UBA5 missense variants disrupt UFM1 activation: Structural, dynamic, and functional dissection.
Ai L, Han W, Xiao S, Huang Y, Zhu Y, Jia B, Xiao Q, Huang W, Duan R
International journal of biological macromolecules 2026 Jan;337(Pt 2):149540
International journal of biological macromolecules 2026 Jan;337(Pt 2):149540
Immunological activity of peach pectins: Insights from cells to animals.
Liu M, Liu X, Blecker C, Bi J
International journal of biological macromolecules 2026 Jan;337(Pt 2):149192
International journal of biological macromolecules 2026 Jan;337(Pt 2):149192
Yigu Decoction polysaccharides mediate gut microbiota and metabolites to promote bone formation-related protein expression and improve osteoporosis.
Zhang R, Yan K, Wu Z, Li G, Cheng F, Chen H, Zhang Y, Ge L, Chen Z, Chen T, Yao X
International journal of biological macromolecules 2026 Jan;336:149301
International journal of biological macromolecules 2026 Jan;336:149301
Histone deacetylase 6 deacetylates and ubiquitinates ATG3 to regulate autophagy.
Yao J, Zhao Z, Chen Y, Xu X, Yang Y, Yue W, Shi X
Cell death and differentiation 2026 Jan;33(1):188-199
Cell death and differentiation 2026 Jan;33(1):188-199
TRIM32 promotes anoikis resistance and metastasis in NSCLC by degrading CHEK2 to enhance IL-6 secretion.
Xu J, Liu W, Chen L, Zhang J, Zhang D, Huang X, Zhang G
Cell death and differentiation 2026 Jan;33(1):126-139
Cell death and differentiation 2026 Jan;33(1):126-139
Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications.
Kang Q, Yuan P, Xie P, Xiao W, Dong L, Guan Z, Zhang K
Molecular medicine reports 2026 Jan;33(1)
Molecular medicine reports 2026 Jan;33(1)
Topology scaffolds-enhanced paracrine of BMSCs through mechanotransduction-related metabolism reprogramming for burn wounds healing.
Zhang Q, Li J, Jia J, He S, Mei A, Zhang Z, Cao Y, Zhang X, Zhang Y, Li Z, Luo G
Biomaterials 2026 Jan;324:123518
Biomaterials 2026 Jan;324:123518
Cadherin 11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit.
Cao X, Jia J, Li Z, Guo S, Duan J, Ma J, Yuan XB, Pan YH
Molecular psychiatry 2026 Jan;31(1):192-208
Molecular psychiatry 2026 Jan;31(1):192-208
Rab2A modulates liver fibroblast growth factor 21 (FGF21) expression and systemic metabolism via apolipoprotein B-CREBH signaling.
Chen ZY, Xu M, Chen S, Chen L
The Journal of biological chemistry 2026 Jan;302(1):110977
The Journal of biological chemistry 2026 Jan;302(1):110977
Integrin β4 drives immune evasion and therapeutic resistance to PD-1 blockade in bladder cancer via MEK/ERK signaling.
Lin P, Xing Z, Hong Y, Xu H, Shao S, Luo L, Zhao Y, Jin X, Li Y
The Journal of biological chemistry 2026 Jan;302(1):110941
The Journal of biological chemistry 2026 Jan;302(1):110941
Lysine demethylase 4A is a centrosome-associated protein required for centrosome integrity and genomic stability.
Chowdhury P, Wang X, Han RI, Motrapu M, Boice AG, Nakatani Y, Vargas-Hernandez S, Love JF, Chew C, Grimm SL, Mezquita D, Mason FM, Martinez ED, Coarfa C, Walker CL, Gustavsson AK, Dere R
The FEBS journal 2026 Jan;293(2):396-417
The FEBS journal 2026 Jan;293(2):396-417
White kidney bean extract improves letrozole-induced polycystic ovary syndrome in rats by regulating the Wnt signaling pathway.
Zhu J, Gu R, Zhu Y, Zhou Q, Zhang Z, Qi X, Wu X, Deng B, Zhong L
The Journal of steroid biochemistry and molecular biology 2026 Jan;255:106858
The Journal of steroid biochemistry and molecular biology 2026 Jan;255:106858
Myeloid-Derived CD38 Mediates Age-Related Endometrial Aging Through NAD(+) Depletion.
Hua L, Liu L, Gao D, Ma L, Jin X, Lu L, Tian S, Jiang X, Jin C, Feng B, Che L, Xu S, Lin Y, Jin L, Zhuo Y, Li M, Wu D
Aging cell 2026 Jan;25(1):e70356
Aging cell 2026 Jan;25(1):e70356
Poly (allylamine hydrochloride)-selenium nanoparticles inhibit porcine reproductive and respiratory syndrome virus by targeting DDX5 and reactive oxygen species.
Yang W, Xu Y, Kang R, Zhang M, Zhang Y, Yang Z, Jing H, Liu Y, Li J, Ge Y, Feng H, Zhou L, Pi J, Liu J
Antiviral research 2026 Jan;245:106324
Antiviral research 2026 Jan;245:106324
Hesperadin sensitizes gastric cancer cells to cisplatin via NOX1-dependent oxidative stress.
Zhu W, Li Q, Ji Z, Wu D, Chen J, Zhao Y, Wu H
Biomedical reports 2026 Jan;24(1):3
Biomedical reports 2026 Jan;24(1):3
Effects of repetitive transcranial magnetic stimulation on apoptosis and MAPK/PI3K-AKT signaling pathways in rats with spinal cord injury.
Xu Q, Su J, Lei Q, Liu J, Wang J, Yang M, Song J, Chen H, Lu J
Brain research bulletin 2026 Jan;234:111687
Brain research bulletin 2026 Jan;234:111687
Sesamin exerts protective effects against diquat-induced acute kidney injury by inhibiting oxidative stress, apoptosis and autophagy: A key role for the SIRT5/FOXO3a signaling pathway.
Han S, Pu Y, Liu Z
Pesticide biochemistry and physiology 2026 Jan;216(Pt 1):106728
Pesticide biochemistry and physiology 2026 Jan;216(Pt 1):106728
Poria cocos polysaccharide inhibits Porcine Deltacoronavirus replication in vitro through regulating apoptosis by PI3K-Akt/NF-κB signaling pathway.
Sun M, Yang J, Liang Y, Deng X, Hong Y, Wen Y, Wang Y, Wu R, Zhao Q, Du S, Yan Q, Cao S, Huang X
Microbial pathogenesis 2026 Jan;210:108188
Microbial pathogenesis 2026 Jan;210:108188
Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged mice.
Yao H, Su Q, Dai Q, Li L, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Japanese encephalitis virus activates the NLRP3/caspase-1/GSDMD signaling pathway in dopaminergic neurons.
Guo X, Lu S, Huang Z, Li J, Cheng G, Hu X, Zhang W, Gu C
PLoS neglected tropical diseases 2026 Jan;20(1):e0013924
PLoS neglected tropical diseases 2026 Jan;20(1):e0013924
Acacetin Alleviates Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease in Mice by Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis.
Xu X, Liu X, Yao L, Yin X
Applied biochemistry and biotechnology 2026 Jan;198(1):640-654
Applied biochemistry and biotechnology 2026 Jan;198(1):640-654
DNA Methylation Patterns of 5mC Regulators: Insights into Immune Microenvironment Regulation in Heart Failure.
Liu Z, Liu M, Xu Y, Zou C
Applied biochemistry and biotechnology 2026 Jan;198(1):619-639
Applied biochemistry and biotechnology 2026 Jan;198(1):619-639
Linoleic acid promotes osteogenic differentiation of bone marrow mesenchymal stem cells and ameliorates ovariectomy (OVX)-induced osteoporosis in mice through the PI3K/AKT pathway.
Liao H, Luo X, Jiang L
The international journal of biochemistry & cell biology 2026 Jan;190:106878
The international journal of biochemistry & cell biology 2026 Jan;190:106878
Isoimperatorin inhibits cell proliferation and induces apoptosis via regulating PI3K/AKT pathway in acute lymphoblastic leukemia.
Xiao J, Wang Y
Molecular immunology 2026 Jan;189:181-191
Molecular immunology 2026 Jan;189:181-191
COA6 deficiency inhibits hepatocellular carcinoma progression by regulating cuproptosis through the JAK/STAT signaling pathway.
Tian K, Yang Y, Niu X, Wei X, Zhang M, Zhou Y, Yang M, Sun H, Zhu L, Liu F
Biochimica et biophysica acta. Molecular cell research 2026 Jan;1873(1):120065
Biochimica et biophysica acta. Molecular cell research 2026 Jan;1873(1):120065
Mechanical stress accelerates vascular calcification by Piezo1/BMP2 of vascular smooth muscle cells.
Li B, Zhao Z, Xia Y, Deng S, Chen X, Jiang N, Ke G, Wen S, Yuan Y, Wu Q, Tao Y, Chen B, Peng S, Huang W, Tang B, Hao W, Deng C, Liu S
Biochimica et biophysica acta. Molecular basis of disease 2026 Jan;1872(1):168061
Biochimica et biophysica acta. Molecular basis of disease 2026 Jan;1872(1):168061
M1 macrophages enhance breast cancer chemoresistance via JAK-STAT3 signaling.
Feng Y, Chen F, Mu C, Wang L, Jiang Y, Liu D, Li D, Liang C, Zhai Y, Yang T, Wells A, Clark AM, Wei L, Ma B
Biochimica et biophysica acta. Molecular basis of disease 2026 Jan;1872(1):168056
Biochimica et biophysica acta. Molecular basis of disease 2026 Jan;1872(1):168056
Corneal biomechanical cues mediated by PAI-2: the origin of PM2.5-induced corneal disease.
Hao S, Xie G, Li D, Su K, Sheng F, Chen L, Gu Y, Jin H, Xu Y, Chen R, Qin Z, Xu D, Xu P, Zhou L, Kong N, Ding H, Chen Z, Liu S, Ji B, Yao K, Fu Q
EMBO molecular medicine 2026 Jan;18(1):120-150
EMBO molecular medicine 2026 Jan;18(1):120-150
METTL1-mediated m7G methylation of FoxO1 regulates lipid metabolism in metabolic dysfunction-associated fatty liver disease.
Du J, Li Y, Zhu X, Gao J, Zhang Y, Wang C, Han D, Qiao L, Kou B, Guo R, Zhang H, Lin J
Metabolism: clinical and experimental 2026 Jan;174:156420
Metabolism: clinical and experimental 2026 Jan;174:156420
Targeted demethylation of the BRD7 promoter based on CRISPR/dCas9 system inhibits the malignant progression of nasopharyngeal carcinoma.
Wei J, Duan Y, Xue C, Zheng L, Wei Q, Wu Z, Xin H, Zeng T, Deng H, Fan S, Xiong W, Zeng Z, Li M, Zhou M
Clinical and translational medicine 2026 Jan;16(1):e70583
Clinical and translational medicine 2026 Jan;16(1):e70583
Melatonin-engineered MSCs-exosomes deliver USP4 to stabilise ARNTL and inhibit clock rhythmic ferroptosis for enhanced flap survival.
Jiang X, Wang Y, Zhang X, Deng H, Fang L, Tafadzwa C, Yao J, Chen H, Ye A, Zhou K, Ling X, Xiao J
Clinical and translational medicine 2026 Jan;16(1):e70565
Clinical and translational medicine 2026 Jan;16(1):e70565
NIR-Triggered Metal-Polyphenol Nanoparticles Enhance HPV-Driven Cancer Immunotherapy via Immunogenic Cell Death and STING Sequential Activation.
Liu M, Zhang J, Chen S, Zheng J, Xiao L, Liu X, Cao Y, Zhu S, Chang S
Advanced healthcare materials 2026 Jan;15(4):e02884
Advanced healthcare materials 2026 Jan;15(4):e02884
A Galactose-Engineered Dual-Responsive Nanocarrier for ASO/CRISPR-Cas9 Delivery to Inhibit HBV Replication.
Chen L, Huang Q, Liu Y, Chen K, Yang Q, Tang H, Wang D, Tang Z
Advanced healthcare materials 2026 Jan;15(4):e02835
Advanced healthcare materials 2026 Jan;15(4):e02835
Autocrine TGF-β1 in Periodontal Ligament-Derived Stem Cell Pellets Enhances Periodontal Regeneration in Class II Furcation Defects of Canine Models.
Xu F, Zhang Z, Fang S, Bai L, Gong Y, Liang X, Yu M, Ahmadi S, Elayah SA, Tu J, Na S
Advanced healthcare materials 2026 Jan;15(2):e02553
Advanced healthcare materials 2026 Jan;15(2):e02553
Batatasin III alleviates slow transit constipation by regulating gut microbiota and inhibiting the NLRP3-IL-1β pathway.
Yin F, Jiang Z, Tong Y, Wang S, Zheng K, Han L, Ma W, Li R, Dou X, Ping Y, Wu B, Fu L, Sun D
The Journal of nutritional biochemistry 2026 Jan;147:110110
The Journal of nutritional biochemistry 2026 Jan;147:110110
Red nucleus IL-15 facilitates the development of neuropathic pain in male rats by inducing inflammatory factors: implying the involvement of NF-κB and p38 MAPK.
Zhang MM, Wang WT, Li YJ, Tao XX, Li K, Chen JM, Yang QQ, Tian X, Yang J, Yu YL, Xu YL, Wu JB, Wang JY, Zeng XY
Brain, behavior, and immunity 2026 Jan;131:106137
Brain, behavior, and immunity 2026 Jan;131:106137
Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury.
Wei Z, Huang S, Zhang W, Wen J, Zhou X, He W, Yang X, Wang H, Zhai G, Shi B, Jin L, Wang D, Feng S, Ye L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e10976
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e10976
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
Zhang S, Xie Y, Zhang L, Qi Y, Liao Q, Xu C, Yang S, Zhou H, Tan Q, Qi S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
NUSAP1 Recruits DAXX to Suppress HIF-Driven Triple-Negative Breast Cancer Progression.
Du Y, Wang J, Wang M, Zhang Y, Zheng M, Li H, Wang X, Sun H, Tang K, Shan C, Zhao Q, Meng X, Wang Y, Zhou J, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e13380
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e13380
Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X-Linked Hypophosphatemic Rickets.
Wu H, Zhao W, Chen X, Wang Y, Wei S, Xiang B, Shi Y, Li Z, Yao Y, Xie J, Qiu R, Shu M, Xu S, Chen P, Chen Z, Wu Y, Xia W, Gao L, Song Y, Zhao J, Xu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e08870
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e08870
Investigation into the Pancreatic Pathogenesis of SFTSV across Multiple Levels.
Liu X, Xu Z, Tong Y, Wang C, Yao Y, Diao Y, Ma J, Zhou S, Du Y, Zhang Z, Xu G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e15862
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e15862
EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non-Small Cell Lung Cancer via Hippo Pathway Activation.
Yang S, Xie H, Lin Q, Zhou L, Liu J, Fang Z, Tang Z, Yuan R, Su J, Li S, Wang W, Pan M, Wang H, Dai X, Wang G, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e10508
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e10508
Site-Specific Mitochondrial RNA N1-Methyladenosine Demethylation via an Engineered MTS-PUF-ALKBH3 Fusion Protein.
Li X, Kong D, Liu H, Yang J, Zhou J, Qian Y, Zhao D, Li J, Wu X, Zhang T, Sun X, Han Y, Lai L, Li Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e10482
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e10482
Pharmacological Enhancement of Integrated Stress Response Confers Protection in Calcific Aortic Valve Disease.
Wang L, Duan X, Liu H, Lin F, Zhou C, Schröder K, Shah AM, Zhao G, Zhang M
JACC. Basic to translational science 2026 Jan;11(1):101433
JACC. Basic to translational science 2026 Jan;11(1):101433
A model of coagulation-related genes for prediction of prognosis in lung adenocarcinoma and verification in vitro.
Li J, Xu L, Yao N, Mao J, Zhao H
Science progress 2026 Jan-Mar;109(1):368504261426216
Science progress 2026 Jan-Mar;109(1):368504261426216
Morin improves postoperative cognitive dysfunction by mediating the miR-138-5p/SIRT1 axis to regulate ferroptosis.
Yang Y, Hu W, Wu Z, Chen M, Li H, Cui J, Wang C, Luo Y, Hu B, Zou X
Scientific reports 2026 Jan 9;16(1):4186
Scientific reports 2026 Jan 9;16(1):4186
Impaired nitrogenous waste clearance promotes hepatocellular carcinoma.
Han X, Shen J, Yan J, Tacke R, Dai W, Mao Q, Queen Daguplo H, Liu S, Islam A, Liu T, Koch MC, Lin RZ, Li H, Anthony T, Xie P, Zhang L, Gao S, Simon MC, Chen X, Yang J, Su X, Zong WX
Science advances 2026 Jan 9;12(2):eaec0766
Science advances 2026 Jan 9;12(2):eaec0766
RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria.
Behera AK, Kim JJ, Kordale S, Pekovic F, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Valkov E, Gonatopoulos-Pournatzis T
Molecular cell 2026 Jan 8;86(1):41-59.e15
Molecular cell 2026 Jan 8;86(1):41-59.e15
Exosomes derived from ADSC suppress endothelial cells ferroptosis and alleviate sepsis acute liver injury via regulation of Keap1/Nrf2/GPX4 axis.
Wang X, Wu D, Liu X, Xu Y, Wang P, Fu H, Ma Y, Liu S, Wang Q, Xu XJ, Dai Z, Zhang Q, Yin W, Shen K, Li J
Stem cells (Dayton, Ohio) 2026 Jan 8;44(1)
Stem cells (Dayton, Ohio) 2026 Jan 8;44(1)
Acupuncture ameliorates diet-induced obesity via the vagal-GLP-1-ARC circuit: neural mechanism of anorexigenic action.
Yang Y, Shao Y, Tian J, Wang Y, Zhu Y, Pan S, Wei X, Jiang L, Wang X, Shu Q
Chinese medicine 2026 Jan 8;21(1):20
Chinese medicine 2026 Jan 8;21(1):20
Ferulic acid in combination with ginsenoside Rb1 alleviates myocardial no-reflow by inhibiting platelet HMGB1 release and NET formation.
Li J, You Y, Wang Y, Zou J, Xiao S, Yin X, Xu J, Liao F, Zhang H, You Y
Chinese medicine 2026 Jan 8;21(1):16
Chinese medicine 2026 Jan 8;21(1):16
NAT10-mediated ac4C modifications regulate glioblastoma progression.
Lin L, Xiong Y, Guo Y, Tu Z, Luo P, Fang Z, Zhang L, Huang K, Wu L
Cell death & disease 2026 Jan 8;17(1):181
Cell death & disease 2026 Jan 8;17(1):181
Phase 1 dose-escalation trial of sub-endometrial injection of human embryonic stem cells-derived immunity-and-matrix-regulatory cells to promote endometrial angiogenesis in refractory intrauterine adhesion.
Li Q, Liao Z, Hu X, Hao J, Lai Y, Sui C, Zhou J, Fang Z, Tian Y, Zhou Y, Li J, Gao T, Fan J, Nan F, Guo Y, Liu W, Wei W, Deng Y, Li Z, Huang B, Zhang H, Feng G, Wang L, Li W, Zhou Q, Jin L, Wu J, Hu B, Qian K
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Jan 7;34(1):423-442
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Jan 7;34(1):423-442
Methotrexate-triggered ferroptosis suppresses oral cancer progression by phosphorylated KEAP1-mediated NRF2 degradation to inhibit SLC7A11/GPX4 signaling pathway.
Yu C, Zhang T, Yuan J, Su Y, Zhang H, Xu L, Li X, Cui J, Xu R, Zhou Y, Huang H, Zhou X, Zhou Y, Zhang E
Cancer cell international 2026 Jan 6;26(1):64
Cancer cell international 2026 Jan 6;26(1):64
Spinal astrocytic EAATs mediate endothelin-1-induced breakthrough cancer pain in mice.
Jiang S, Huang D, Huang L, Li X
Neurological research 2026 Jan 6;:1-14
Neurological research 2026 Jan 6;:1-14
CD36 as a potential prognostic biomarker and modulator of the tumor microenvironment in glioma.
Xu L, Sun P
Translational cancer research 2026 Jan 31;15(1):19
Translational cancer research 2026 Jan 31;15(1):19
Simvastatin Alleviates ConA-Induced Autoimmune Hepatitis by Inhibiting CD4(+) T Cell Activation via Calcium-NFATC3 Pathway.
Wang X, Long T, Zhou L, Xu N, Fang P, Li B, Xu H, Sun G, Zhang D, Jin H
Inflammation 2026 Jan 30;49(1):72
Inflammation 2026 Jan 30;49(1):72
Artemisinin-hydroxychloroquine combination from traditional antimalarial medicine attenuates pulmonary fibrosis via PI3K/AKT/GSK3β-mediated inhibition of epithelial-mesenchymal transition.
Zhang L, Yu L, Deng D, Liang Q, Du H, Mei M, Deng C, Song J, Guo W
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120717
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120717
Fuxin decoction regulates the Nrf2/SLC7A11/GPX4 pathway to ameliorate doxorubicin-induced ferroptosis in cardiomyocytes.
Han Q, Guo Y, Yu Y, Shi J, Yuan H, Yu H, Liu X, Xue Y, Li Y
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120037
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120037
Chrysanthemum morifolium Ramat. water extract prevents and treats metabolic-associated fatty liver disease via pan-PPAR activity.
Zhu W, Chang W, Chen T, Li M, Han Z, Sun N, Fang W, Wang D
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120571
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120571
Neuronal Subtype-Specific Expression of γ-Enolase: Its Role in Neuronal Differentiation.
Horvat S, Pečar Fonović U, Zidar N, Doljak B, Kos J, Pišlar A
Neuromolecular medicine 2026 Jan 30;28(1):4
Neuromolecular medicine 2026 Jan 30;28(1):4
The METTL3-IGF2BP3 axis drives osteosarcoma progression by enhancing ID1 mRNA stability.
Shu R, Cheng Q, Yu Z, Zhou H, Lin M, Shi M, Chen J, Chen J, Zhao M
BMC musculoskeletal disorders 2026 Jan 30;27(1)
BMC musculoskeletal disorders 2026 Jan 30;27(1)
Acrylamide disrupts meiotic G2/M transition and SAC activity during oocyte maturation.
Chen S, Wang PX, Wang YT, Ke XH, Ou M, Sun SC, Liao BY, Chen X
Biology direct 2026 Jan 30;21(1)
Biology direct 2026 Jan 30;21(1)
α-terpineol induces apoptosis in melanoma cells and its underlying mechanism.
Liu W, Xiao Y, Zan X, Qi J, Ma T, Long Q, Wu B, Cao Y
Scientific reports 2026 Jan 3;16(1):4278
Scientific reports 2026 Jan 3;16(1):4278
PiR48444 inhibits MSC osteogenic differentiation and bone regeneration via targeting METTL7A/eIF4E-mediated BMP2 m6A methylation.
Zheng Z, Li X, Qin W, Yu S, Xu T, Cheng H, Xie W, Fu Z, Pan G, Zhang Y, Huang W, Liu F, Jiang Y, Jaspers RT, Pathak JL, Wu L
Communications biology 2026 Jan 29;9(1)
Communications biology 2026 Jan 29;9(1)
Targeting glucocorticoid receptor to enhance immunotherapy response in triple negative breast cancer.
Yang L, Chen Z, Chen Y, Yang J, Liu S, Deng K, Xu J, Cui M, Fu Z
Breast cancer research : BCR 2026 Jan 29;28(1)
Breast cancer research : BCR 2026 Jan 29;28(1)
BPC157 drives angiogenesis through FBXO22-dependent stabilization of BACH1.
Zhang J, Liu M, Ou H, Wang Z, He L, Xiao Y, Xie F, Yu D, Cao H, He W, Wang S, Zhang W, Zhang K, Zhang Y, Li M, Hao Q
Cell communication and signaling : CCS 2026 Jan 29;24(1)
Cell communication and signaling : CCS 2026 Jan 29;24(1)
Role of p38 MAPK in the cytokine reprogramming of a human leukemic cell line with a drug-resistant phenotype.
Cadenas-Garrido P, García-Serna AM, Parrado A, Martínez-García J, Herrera-Suarez M, Cánovas M, de Diego Puente T, Saceda M, Pelegrin P, Díaz-Carrasco MS, Martín-Orozco E
Cell communication and signaling : CCS 2026 Jan 29;24(1)
Cell communication and signaling : CCS 2026 Jan 29;24(1)
Quercetin alleviates LPS-induced inflammatory response in dairy cow lamellar keratinocytes through PI3K/Akt/NF-κB signaling pathway.
Zhai C, Wu Q, Yang X, Xie Y, Mu J, Lei L, Shi M, Wu W, Li G, Ding J
BMC veterinary research 2026 Jan 28;22(1)
BMC veterinary research 2026 Jan 28;22(1)
IL-4/Nanohydroxyapatite Codelivery in a Dual-Bionic Scaffold: Design and Immunomodulatory Endogenous Osteogenesis Mechanism.
Wang FZ, Yu Y, Soh HY, Liu S, Hu LH, Tang ZN, Zhang WB, Peng X
ACS applied materials & interfaces 2026 Jan 28;18(3):5998-6017
ACS applied materials & interfaces 2026 Jan 28;18(3):5998-6017
Systematic evaluation of mitochondrial morphology regulators for amelioration of neuronal α-synucleinopathy.
Kim SY, Choi J, Jang DC, Lee PR, Hong GS, Kim J, Jeong WK, Han K, Kwon SK
NPJ Parkinson's disease 2026 Jan 27;12(1)
NPJ Parkinson's disease 2026 Jan 27;12(1)
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway.
Yin H, Han X, Zhang Q, Li D, Wang F
European journal of histochemistry : EJH 2026 Jan 26;70(1)
European journal of histochemistry : EJH 2026 Jan 26;70(1)
Cyclin D1/D2-CDK4 Drives Cell Migration by Orchestrating Cytoskeletal Dynamics Through a TGFβ-FAK-Rac1 Axis.
Guo R, Wang Y, Zhang A, Jirawatnotai S, Chu C, Liu L
International journal of molecular sciences 2026 Jan 26;27(3)
International journal of molecular sciences 2026 Jan 26;27(3)
HAGLR promotes endometriosis progression via the miR-185-5p/VEGFA axis and serves as a potential diagnostic biomarker.
Wu X, Liang H, Cao Y, Hao S, Bie Y
BMC women's health 2026 Jan 24;26(1):112
BMC women's health 2026 Jan 24;26(1):112
Construction and Biological Characterization of ORF133-Deletion Mutant of Lumpy Skin Disease Virus.
Ke Q, Li M, Peng Y, Wang X, Sun Y, Yin X, Wei Y
Viruses 2026 Jan 24;18(2)
Viruses 2026 Jan 24;18(2)
Essential role of NONO-HOXA1-Wnt axis in cardiomyocyte differentiation.
Feng Z, Gao Y, Gao H, Sun S, Na W, Huang X, Li S, Tan C, Min S, Lu Y, Zhuang Q, Lin S, Ma X, Liu Y, Shou W, Wang M, Wang J, Gu Z, Sheng W, Wu F, Huang G
Nature communications 2026 Jan 24;17(1)
Nature communications 2026 Jan 24;17(1)
A paraventricular hypothalamic control of social stress susceptibility by targeting brown adipose tissue β3 adrenoceptor.
Du X, Zhang J, Wang Q, Zhou D, Zhang W, Song L, Cui M, Ge T, Zhai X, Yu Y, Yang J, Hu A, Zhang H, Cao JL, Wu Z
Communications biology 2026 Jan 23;9(1)
Communications biology 2026 Jan 23;9(1)
Structural basis of co-translational N-myristoylation in humans.
Denk T, Monassa P, Musial J, Berninghausen O, Beatrix B, Giglione C, Meinnel T, Beckmann R
Nature communications 2026 Jan 23;17(1):1191
Nature communications 2026 Jan 23;17(1):1191
Loss of Epithelial Homeostasis Driven by TMBIM1 Depletion via E-Cadherin Junction Disassembly.
Sun Z, Zhang L, Qi J, Jiang M, Jiang S, Zhu Z, Ling Y, Wang X, Li J
International journal of molecular sciences 2026 Jan 22;27(2)
International journal of molecular sciences 2026 Jan 22;27(2)
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
Deng Q, Chen Y, Chen Z, Fu Z
Cancer cell international 2026 Jan 22;26(1)
Cancer cell international 2026 Jan 22;26(1)
Vasicine Attenuates Allergic Asthma by Suppressing Mast Cell Degranulation and Th2 Inflammation via Modulation of the FcεRI/Lyn + Syk/MAPK Pathway.
Qu L, Du W, Ren Z, Chen M, Wu X, Cao X, Rao G, Tong X, Huang F, Sun Y
Pharmaceuticals (Basel, Switzerland) 2026 Jan 22;19(1)
Pharmaceuticals (Basel, Switzerland) 2026 Jan 22;19(1)
Nuclear activities and interactome of the NS5 protein of Tick-Borne Encephalitis Virus.
Chazal M, Sow AA, Le Seac'h E, Hawasheen D, Bonifacio M, Feracci M, Gracias S, Sogues A, Molho M, Pan H, Bonaventure B, Quivy JP, Almouzni G, Decroly E, Ramage H, Johnson JR, Caval V, Jouvenet N
bioRxiv : the preprint server for biology 2026 Jan 21;
bioRxiv : the preprint server for biology 2026 Jan 21;
Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer.
Zhan W, Fu Y, Liu Y, Cai R, Bai F, Guo C, Cheng Y, Wu Z, Qin G, Xie Y, Zhang J, Deng Y
Cell reports. Medicine 2026 Jan 20;7(1):102534
Cell reports. Medicine 2026 Jan 20;7(1):102534
The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis.
Meng F, Du Y, Liang J, Li H, Wang J, Tang K, Kong R, Sun H, Yin T, Qin J, Yang X, Shan C, Liu M, Yang G, Zhang J, Wang Y, Zhou J, Chen Y
Nature communications 2026 Jan 20;17(1):614
Nature communications 2026 Jan 20;17(1):614
VILMIR is a trans-acting long noncoding RNA that enhances the host interferon response in human epithelial cells.
John K, Smith E, Istishin A, Mahmood N, Diveley K, Tollison TS, Carpenter S, Peng X
Journal of virology 2026 Jan 20;100(1):e0138025
Journal of virology 2026 Jan 20;100(1):e0138025
MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
Pan T, Zhu J, Wang X, Tang D, Wang Z, Yang Y, Teng Y, Tian Q, Dan G, Chen C, Yu D, Liu M, Wang H, Zhang T, Guo B, Chen T, Jin B
Cancer research 2026 Jan 2;86(1):146-166
Cancer research 2026 Jan 2;86(1):146-166
METTL3-mediated m(6)A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca(2+) signaling.
Chen C, Xiong K, Liang F, Zhong Y, Qin X, Huang N, Fang Y, Zhu B, Cheng J, Wei Q, Zheng L, Zhao J
Molecular cancer 2026 Jan 19;25(1)
Molecular cancer 2026 Jan 19;25(1)
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Li Y, Lu W, Qian W, Liao X, Wang P, Wang Y, Jiao W, Wang M, Zhao J, Yang J, Gao H, Li H
Nutrients 2026 Jan 19;18(2)
Nutrients 2026 Jan 19;18(2)
PRSS23 promotes pancreatic cancer progression through regulating Hippo-YAP activity.
Liu Z, Jiang Q, Sun Y, Song Y, Yu B
Biochemical and biophysical research communications 2026 Jan 18;796:153157
Biochemical and biophysical research communications 2026 Jan 18;796:153157
CNOT3 resists ovarian aging by accelerating oocyte maturation and promoting ESCs differentiation.
Li N, Huang E, Wang R, Li J, Yuan X
Stem cell research & therapy 2026 Jan 17;17(1):83
Stem cell research & therapy 2026 Jan 17;17(1):83
MARCHF1-mediated SULF1 degradation blocks THBS2/TGF-β/SMAD2/3 signaling to reverse colon cancer metastasis and 5-FU resistance.
Li H, Xie Y
iScience 2026 Jan 16;29(1):114476
iScience 2026 Jan 16;29(1):114476
Partial embryo loss caused by disruption of the placental hormone CTRP6 coincides with dNK cell abnormalities during pregnancy.
Fan H, Chen X, Du C, Chen S, Yu W, Tang Y, Wang Y, Wang H, Bao W, Cao B, Sun MA
iScience 2026 Jan 16;29(1):114434
iScience 2026 Jan 16;29(1):114434
Targeted PGC-1α gene delivery by GV-assisted ultrasound cavitation for renal ischemia-reperfusion injury therapy.
Kuai Y, Xu W, Wang X, Xu X, Huang P
iScience 2026 Jan 16;29(1):114374
iScience 2026 Jan 16;29(1):114374
A causal coding variant regulating alternative splicing of DOC2A at 16p.11.2 GWAS locus influences susceptibility to schizophrenia.
Zhou D, Zhang Y, Yang Z, Zhang C, Zhang Q, Huo J, Cui K, Wu Y, Chang H, Wang C, Xiao X, Cai X, Li M
Science advances 2026 Jan 16;12(3):eadw7667
Science advances 2026 Jan 16;12(3):eadw7667
Chitinase-3-like protein 1 depletion in glioma cells alters tumor microenvironment and normalizes neovasculature in human glioma xenografts.
Cyranowski S, Zawadzka M, Ghosh M, Wojtas B, Malik AR, Poleszak K, Waśniewski K, Baluszek S, Swatler J, Wojnicki K, Gielniewski B, Kaza B, Klejman A, Łukasik H, Kaminska B
Cell communication and signaling : CCS 2026 Jan 15;24(1):103
Cell communication and signaling : CCS 2026 Jan 15;24(1):103
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
Ma D, Yu W, Zhou H, Lin R, Sun X, Peng M, Lin C, Du H, Li Y, Liang H, Sun D, Liu P, Lu J
Cell death & disease 2026 Jan 15;17(1):43
Cell death & disease 2026 Jan 15;17(1):43
IL-24 ameliorates cognitive dysfunction via the inhibition PERK-eIF2α Signaling pathway in Alzheimer's disease.
Du Y, Zheng X, Yue X, Fu P, Diao J, Zhang A, Cheng H, Yang H, Bi J, Zhou Q, Wang P
International immunopharmacology 2026 Jan 15;169:116039
International immunopharmacology 2026 Jan 15;169:116039
DXFD-1 alleviates DSS-induced ulcerative colitis by targeting NF-κB and Nrf2 signaling.
Li S, Fu X, Cheng C, Zhao Y, Wu T, Xu G
International immunopharmacology 2026 Jan 15;169:115934
International immunopharmacology 2026 Jan 15;169:115934
S-nitrosylation of IRF7 induced by NOS1 expression in melanoma suppresses anti-tumor immunity.
Dai Y, Zeng S, Li K, Huang J, Yang M, Gao W, Chen X, Huang M, Ye S, Wang Q, Chen J, Zhu L, Zhong Z, Yuan S, Guo S, Liu N, Hao B, Liu Q
Cell death & disease 2026 Jan 14;17(1):33
Cell death & disease 2026 Jan 14;17(1):33
Crystal structure of Echinococcus multilocularis cystatin B reveals a novel feature in classical stefins.
Hong W, Cheng Z, Xu Z, Zhong S, Liu X, Dibo N, Dai Z, Lin Y, Lai W, Jia H, Shang X, Huang S
Scientific reports 2026 Jan 13;16(1):5114
Scientific reports 2026 Jan 13;16(1):5114
Multi-omics analysis identifies BUB1B as a cell cycle-related driver of bladder cancer progression.
Zhou H, Peng S, Ling Z, Cai J, Liu J, Kong Y, Zhang H, Ouyang J, Zhang J
World journal of surgical oncology 2026 Jan 12;24(1):71
World journal of surgical oncology 2026 Jan 12;24(1):71
IL-25-ILC2-IL-13 axis improves traumatic brain injury by mediating CXCL-10-dependent regulation of blood brain barrier integrity.
Peng M, Shu D, Chen Z, Yang Z, Zhang M, Wang Q, Shao X
Journal of neuroinflammation 2026 Jan 12;23(1):53
Journal of neuroinflammation 2026 Jan 12;23(1):53
Atypical tetracyclines promote longevity and ferroptotic neuroprotection via translation attenuation.
Clay KJ, Sanchez-Alavez M, Newman I, Na N, Verduzco Espinoza AP, To A, Saad S, Cline HT, Petrascheck M
bioRxiv : the preprint server for biology 2026 Jan 11;
bioRxiv : the preprint server for biology 2026 Jan 11;
Huashi Baidu granules alleviates LPS-induced acute lung injury by targeting TACE-mediated inflammatory signaling and stress granules disassembly.
Ma Y, Zhang J, Gong J, Yang W, Huang J, Sun Y
Journal of ethnopharmacology 2026 Jan 10;354:120580
Journal of ethnopharmacology 2026 Jan 10;354:120580
The renoprotective anti-hyperuricemia effect of Cornus officinalis extract in hyperuricemia rats based on network pharmacology and multiple omics.
Ding B, Liu J, Kasay ILT, Konsue N, Lin X, Yan F, Wang D, Lv C, Xia H, Qin S
Journal of ethnopharmacology 2026 Jan 10;354:120519
Journal of ethnopharmacology 2026 Jan 10;354:120519
Decoding the healing secrets of Gegenqinlian decoction: A promising approach to radiation-induced intestinal injury.
Zhang M, Wang SJ, Du XQ, Li GA, Yu YY, Zhang YQ, Liu WJ, Song F, Cao W, Sun Y, Li XQ
Journal of ethnopharmacology 2026 Jan 10;354:120473
Journal of ethnopharmacology 2026 Jan 10;354:120473
Disruption of zinc homeostasis reduces histone acetylation levels in normal and tumor cells.
Xu S, Hu Y, Tang C, Xu W
Scientific reports 2026 Jan 10;16(1):4983
Scientific reports 2026 Jan 10;16(1):4983
PHB1 Attenuates Triptolide-induced Cardiotoxicity by Regulating Mitochondrial Dynamics in Cultured Newborn Mice Cardiomyocytes.
Chen W, Li X
Journal of cardiovascular pharmacology 2026 Jan 1;87(1):51-60
Journal of cardiovascular pharmacology 2026 Jan 1;87(1):51-60
UDP-glucuronosyltransferase 1A9 function is mediated by the two C-terminal lysine residues and proper mobility/flexibility of the cytoplasmic tail.
Miyauchi Y, Sadato Y, Sawai M, Takechi S, Hiratsuka M, Mackenzie PI, Ishii Y
Biochemical and biophysical research communications 2026 Jan 1;794:153004
Biochemical and biophysical research communications 2026 Jan 1;794:153004
Curzerene Ameliorates Depression-Like Behaviors and Cognitive Impairment by Modulating the Gut Microbiota and HMGB1/RAGE/TLR4 Pathway.
Huang F, Ma X, Xu X, Zhang J, Wang C, Song R, Wang X, Chen M, Qi Y
Biomolecules & therapeutics 2026 Jan 1;34(1):174-188
Biomolecules & therapeutics 2026 Jan 1;34(1):174-188
Inhibition of the PI3K/AKT signaling pathway blocks the oncogenic activity of TRIM26 in prostate cancer cells.
Zhong YY, Zhang LH, Zhou XY, Zhou XM, He YM, Mao XL, Xu XF
Asian journal of andrology 2026 Jan 1;28(1):89-95
Asian journal of andrology 2026 Jan 1;28(1):89-95
Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood-brain barrier.
Wang Y, Chen R, Shi G, Huang X, Li K, Wang R, Cao X, Yang Z, Zhao N, Yan J
Neural regeneration research 2026 Jan 1;21(1):377-391
Neural regeneration research 2026 Jan 1;21(1):377-391
Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress.
Liao Y, Zhang Q, Shi Q, Liu P, Zhong P, Guo L, Huang Z, Peng Y, Liu W, Zhang S, Adorján I, Fukuzaki Y, Kawashita E, Zhang XQ, Ma N, Zhang X, Molnár Z, Shi L
Neural regeneration research 2026 Jan 1;21(1):333-345
Neural regeneration research 2026 Jan 1;21(1):333-345
Mechanism of Atractylodis Rhizoma in improving cognitive dysfunction in Alzheimer's disease by regulating the cAMP/CREB/BDNF pathway.
Xu X, Zhao Y, Ma H, Hu Y, Yu L, Su Y, Song J, Xie Z, Zhang Z, Wang P
International immunopharmacology 2026 Jan 1;168(Pt 2):115923
International immunopharmacology 2026 Jan 1;168(Pt 2):115923
Inhibition of neutrophil infiltration and NETosis ameliorates sepsis-induced cardiac injury and reduces myocardial inflammation and apoptosis.
Xue J, Ren Y, Chen Y, Zhu H, Wang Y
International immunopharmacology 2026 Jan 1;168(Pt 1):115862
International immunopharmacology 2026 Jan 1;168(Pt 1):115862
Macrophage-specific UBA1 knockout attenuates sepsis-induced liver dysfunction by regulating inflammatory responses via the BMAL1/CLOCK-REV-ERBα axis.
Jin LY, Cui C, Lv SY, Li HH
International immunopharmacology 2026 Jan 1;168(Pt 1):115799
International immunopharmacology 2026 Jan 1;168(Pt 1):115799
BNIP3-mediated mitophagy alleviates traumatic brain injury by inhibiting neuronal apoptosis and oxidative stress.
Yin H, Wei Y, Han Z, Li Z, Liu K, Zhu L
International immunopharmacology 2026 Jan 1;168(Pt 1):115793
International immunopharmacology 2026 Jan 1;168(Pt 1):115793
Polyethylene terephthalate microplastics exposure enhances the risk of ulcerative colitis: insights from multiomics integration, machine learning, and molecular docking reveal intestinal toxicity mechanisms.
Yang X, Yan B, Zhao Y, Zhou L, Liu M, Chen G, Shen L, Deng T
International journal of surgery (London, England) 2026 Jan 1;112(1):735-750
International journal of surgery (London, England) 2026 Jan 1;112(1):735-750
Integrated analysis of bulk RNA and single-cell RNA sequencing data reveals potential biomarkers and immune infiltrates associated with N7-methylguanosine in osteoarthritis.
Sun H, Chen K, Xiong Z, Zhuang Y, Liu M, Ning X, Yang H
International journal of surgery (London, England) 2026 Jan 1;112(1):595-613
International journal of surgery (London, England) 2026 Jan 1;112(1):595-613
Elucidating the causal effects of plasma metabolites on breast cancer from multiple perspectives.
Fang K, Zhou Y, Wu S, Li D, Cui X, Sun S, Li X, Liu C
International journal of surgery (London, England) 2026 Jan 1;112(1):537-552
International journal of surgery (London, England) 2026 Jan 1;112(1):537-552
Asiatic acid reverses cisplatin resistance in A549/DDP cells by activating the P38 MAPK/Slug pathway.
Yu M, Zhang Q, Shang W, Wei S, Wen H, Huo S, Li X, Li X, Zhang H, Tian Y
Tissue & cell 2026 Feb;98:103145
Tissue & cell 2026 Feb;98:103145
Targeting mesenchymal monocyte-derived macrophages to enhance the sensitivity of glioblastoma to temozolomide by inhibiting TNF/CELSR2/p65/Kla-HDAC1/EPAS1 axis.
Gao W, Long X, Lin X, Deng K, Li D, Huang M, Wang X, Liu Q, Wu M
Journal of advanced research 2026 Feb;80:925-941
Journal of advanced research 2026 Feb;80:925-941
PTPN22 as a therapeutic target in intervertebral disc degeneration: Modulating mitophagy and pyroptosis through the PI3K/AKT/mTOR axis.
Liang H, Yang S, Huang Y, Zhu Y, Wu Q, Wu Z, Li S, Shi Y, Chen Z, Jin H, Wang X
Journal of advanced research 2026 Feb;80:775-789
Journal of advanced research 2026 Feb;80:775-789
SA supplementation during lactation promotes learning and memory by reducing H3K27me3 levels.
Huang C, Ai S, Wang M, Li C, Wang K, Nie M, Zhang H, Gu X, Wang HL
Journal of advanced research 2026 Feb;80:301-316
Journal of advanced research 2026 Feb;80:301-316
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries.
Jiang X, Zhang X, Deng H, Lin L, Wang Y, Wang Y, Huang J, Yang N, Xu S, Wang J, Shi K, Tao K, Chen Z, Cai F, Zhou K, Xiao J
Journal of advanced research 2026 Feb;80:265-285
Journal of advanced research 2026 Feb;80:265-285
The Deubiquitinating Enzyme USP46 Abolishes Cell Survival of Prostate Cancer via Enhancing BECN1-Dependent Autophagy.
Yang Y, Cao H, Sun P, Feng Y, Chen L, Gao R
Biotechnology and applied biochemistry 2026 Feb;73(1):231-238
Biotechnology and applied biochemistry 2026 Feb;73(1):231-238
Characterizing Chemokine Signaling Pathways and Hub Genes in Calcium Oxalate-Induced Kidney Stone Formation: Insights from Rodent Models.
Wang B, Tan Z, She W, Wang X, Guan X, Tao Z, Guo F, Xu H, Deng Y
Biochemical genetics 2026 Feb;64(1):430-445
Biochemical genetics 2026 Feb;64(1):430-445
Mitochondrial Function Is Required to Preserve Viability of Stem Cells From the Apical Papilla Following Porphyromonas endodontalis Infection.
Lei S, Li J, Wang XC, Yu S, Wang AC, Yang N, Gao MC, Chen X
International endodontic journal 2026 Feb;59(2):225-237
International endodontic journal 2026 Feb;59(2):225-237
Single-immunocyte transcriptomics reveal the role of natural killer cell-dependent exogenous antigen presentation in ankylosing spondylitis severity.
Ke D, Dai H, Su Y, Zhu H, Liu X, Bai X, Zhang C, Xu J, Zhang J
Experimental & molecular medicine 2026 Feb;58(1):254-271
Experimental & molecular medicine 2026 Feb;58(1):254-271
Piezo1 activation in endothelial cells aggravates microvascular ischemia-reperfusion injury in limbs by enhancing ferroptosis.
Chen FF, Zhang YH, Wu ZC, Du K, Chen X, Lu Y, Hu Q, Du A, Du S, Wang J, Shi K, Chen Z, He Z, Zhou K, Xiao J
Experimental & molecular medicine 2026 Feb;58(1):143-160
Experimental & molecular medicine 2026 Feb;58(1):143-160
Aberrant miR-378 expression promotes hepatic lipid accumulation via hijacking the bile acid-regulated autophagy.
Niu Z, Yan Y, Liu W, Yao Q, Chen J, Shen S, Yu J, Ma M, Li Z, Wu Y, Li Y, Hu C, Zeng H, Gao X, Li Y, Jiang J, Ying H
Life metabolism 2026 Feb;5(1):loaf038
Life metabolism 2026 Feb;5(1):loaf038
Deletion of hepatic growth hormone receptor contributes to the pathogenesis of lean MAFLD by elevating CD36.
Yu D, Yang X, Zhang X, Wang X, Pu Z, Mi A, Ran L, Zhang F, Liang B, Wu Y
Life metabolism 2026 Feb;5(1):loaf037
Life metabolism 2026 Feb;5(1):loaf037
The Virulence-Associated CAP/PR1-Like Proteins From Cytospora chrysosperma Target a Subunit of RNA Polymerase II to Suppress Plant Immunity.
Han Z, Xiong D, Wu H, Yang Y, Tian C, Schneiter R
Plant, cell & environment 2026 Feb;49(2):1151-1169
Plant, cell & environment 2026 Feb;49(2):1151-1169
Diagnostic potential of neutrophil extracellular traps in ulcerative colitis: a gene-based predictive model.
Liang H, Xu Y, Zhang X, Han Z, Zhu J
Molecular and cellular biochemistry 2026 Feb;481(2):923-945
Molecular and cellular biochemistry 2026 Feb;481(2):923-945
Neuroprotective effects of dexmedetomidine in spinal cord injury via modulating PERK/ATF4 pathway.
Yang L, Long B, Yang H
Neurological research 2026 Feb;48(2):147-154
Neurological research 2026 Feb;48(2):147-154
Effects of Piperine on Obese and Lean Nonalcoholic Fatty Liver Disease in Mice.
Fan JB, Qin LQ, Ding L, Zhang L, Shao MM, Tong X, Xu JY
Journal of gastroenterology and hepatology 2026 Feb;41(2):753-762
Journal of gastroenterology and hepatology 2026 Feb;41(2):753-762
Integrating UPLC-HR-MS, network pharmacology and experimental validation to reveal the potential mechanism of Fuzheng Bixie granules in treating acute lung injury.
Yang L, Wu Z, Li Y, Ren G, Spáčil R, Ren W, Xu H
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(3):4589-4605
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(3):4589-4605
Network pharmacology, molecular docking, molecular dynamics simulation, and in vivo experiments elucidate the potential mechanisms of berberine against liver injury.
Zhang L, Cheng L, Huang Q, Yu Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(3):3727-3742
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(3):3727-3742
Piezo1 mediated scaffold-free rapid generation of self-mineralized bone organoids via activating Wnt signaling.
Zhang L, Zhang Y, Wan Z, Yuan X, Gao Y, Song R, Liu X, Sang J, Song J, Wang Y, Zhao Y, Yuan Z
Materials today. Bio 2026 Feb;36:102620
Materials today. Bio 2026 Feb;36:102620
CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation.
Shao Q, Zhang J, Wang H
Molecular medicine reports 2026 Feb;33(2)
Molecular medicine reports 2026 Feb;33(2)
Subcellular distribution of Prussian blue nanozymes dictates enzymatic activity and macrophage polarization for effective colitis therapy.
Ding H, Long M, Wu Y, Zhang Y, Yang Z, Yan X, Li Y, Shen Y, Zhang M, Zhang Y, Sheng J, Gu N
Biomaterials 2026 Feb;325:123622
Biomaterials 2026 Feb;325:123622
Enhanced osteointegration of implants in aged rats via a stem cell pool aging reversion strategy.
Li X, Luo X, He Y, Zhou B, Xu K, Huang Q, Jiang X, Xiong H, Liu X, Liu S, Tao B, Liu P, Cai K
Biomaterials 2026 Feb;325:123604
Biomaterials 2026 Feb;325:123604
Hydrogen-Mediated Activation of the Nrf2/HO-1 Signaling Pathway Improves Cognitive Impairment in Sleep-Deprived Mice.
Xiao Q, Zhou S, Tang B, Zhu Y
CNS neuroscience & therapeutics 2026 Feb;32(2):e70770
CNS neuroscience & therapeutics 2026 Feb;32(2):e70770
A prognostic model for human papillomavirus-negative head and neck squamous cell carcinoma based on a novel ferroptosis-related gene signature: Development, validation and elucidation of its relationship with the immune microenvironment.
Li J, Ab Rahman N, Mohamad S, Yang G
Oncology letters 2026 Feb;31(2):72
Oncology letters 2026 Feb;31(2):72
Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer.
Wang X, Mi B, Lv J, Tang X, Huang J, Liu F, Xing Y, Wen X, Wang Y, Zhong Y
Oncology letters 2026 Feb;31(2):62
Oncology letters 2026 Feb;31(2):62
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Dou T, Zhu X, Li H, Wang R, He J, Geng H, Zhang W, Yu Q, Zhao H, Yang H
Genes and immunity 2026 Feb;27(1):91-105
Genes and immunity 2026 Feb;27(1):91-105
Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury.
Wang Y, Zhu C, Lv S, Huang X, Wang J, Yuan S, Yang Y, Ding X, Shen Z, Zhang X
Genes and immunity 2026 Feb;27(1):25-40
Genes and immunity 2026 Feb;27(1):25-40
Bawei Chenxiang Pills Exert Anti-Myocardial Ischemia Effect by Inhibiting Inflammation Through the TLR4/NF-κB/NLRP3 Signaling Pathway.
Kang L, Yang G, Ding Q, Wang J, Tosheel UB, Xiao Y, Zhou F, Gao X, Norbu K, Chai X
Chemistry & biodiversity 2026 Feb;23(2):e03537
Chemistry & biodiversity 2026 Feb;23(2):e03537
Crustacean Mab21 proteins drive tissue-specific antiviral immunity by activating IKKε outside the canonical nucleic-acid sensing paradigm.
Li H, Li Q, Yang H, Wang X, Lv A, Di X, Wang R, Wang S, Yin B, He J, Li C
PLoS pathogens 2026 Feb;22(2):e1013986
PLoS pathogens 2026 Feb;22(2):e1013986
Cell death modulation dictates tissue-specific tropism of lumpy skin disease virus.
Wen Y, Wang T, Zhang S, Wang J, Li C, Liu C, Tang F, Dai J, Xue F
PLoS pathogens 2026 Feb;22(2):e1013982
PLoS pathogens 2026 Feb;22(2):e1013982
Oncometabolite 5-IP(7) inhibits inositol 5-phosphatase to license E-cadherin endocytosis.
Zhang H, Zhang B, Zhao Y, Su Y, Peng Y, Yang X, Zhao H, Liu H, Feng J, Pei H, Zhang W, Huang N, Jiang K, Ito M, Liu G, Jork N, Anderson KE, Zhao L, Nagata E, Jessen HJ, Hawkins PT, Du C, Rao F
Nature chemical biology 2026 Feb;22(2):293-306
Nature chemical biology 2026 Feb;22(2):293-306
Exosomal FOSL1 From Cancer-associated Fibroblasts Drives the Progression and Pro-tumorigenic M2 Macrophage Polarization of Hepatocellular Carcinoma By Activating PLAU Transcription.
Bai K, Liang R, Li J, Zhao K
Applied biochemistry and biotechnology 2026 Feb;198(2):822-842
Applied biochemistry and biotechnology 2026 Feb;198(2):822-842
An explainable predictive machine learning model reveals ARRB2 as a key gene in post-traumatic stress disorder: A GEO database study.
Wu L, Fu Q, Gao Y, Jiang B, Zheng H, Zhong Z, Zhang G, Lu Y, Zhang Z, Li R, Lu G, Sun L
Journal of psychiatric research 2026 Feb;193:543-560
Journal of psychiatric research 2026 Feb;193:543-560
Integrated bioinformatics and machine learning analysis identify CROT as a regulator of immunological features in idiopathic pulmonary fibrosis.
Song T, Bu M, Song Q, Zhan B, Liu W, Hu M, Xu G, Yang Z, Zhao K, Bai Y, Yao S, Zhao Y
Biochimica et biophysica acta. Molecular basis of disease 2026 Feb;1872(2):168100
Biochimica et biophysica acta. Molecular basis of disease 2026 Feb;1872(2):168100
Exploring the relationship between gut microbiota-metabolite axis and Jiawei Danxuan Koukang's therapeutic effects in male rats with oral submucous fibrosis: A multi-omics analysis.
Wang C, Dai Y, Ye Y, Zeng Q, Tan J
Archives of oral biology 2026 Feb;182:106480
Archives of oral biology 2026 Feb;182:106480
Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini-chromosome maintenance complex and causes DNA damage.
Tsuyama T, Takayama N, Tanaka R, Arai Y, Yamaguchi Y, Nawata Y, Azuma Y, Tada S
FEBS open bio 2026 Feb;16(2):352-364
FEBS open bio 2026 Feb;16(2):352-364
COL1A1 promotes clear cell renal cell carcinoma progression through the Wnt/β-catenin signaling pathway.
Ji X, Yun Y, Zhu Z, Wu T, Ruan M, Fan Y, Zhang Q
Cellular signalling 2026 Feb;138:112259
Cellular signalling 2026 Feb;138:112259
CUEDC2 improves pyroptosis and kidney damage in diabetic kidney disease by inhibiting NLRP3 inflammasome activation.
Yang P, Fan L, Yuan D, Xie J, Luo Y, Zeng Q, Lin W, Li Z, Huang Z, Jiang W, Wang M, Huang Y
Cellular signalling 2026 Feb;138:112239
Cellular signalling 2026 Feb;138:112239
Notoginsenoside R1 as a Protector Against Gentamicin Ototoxicity: Targeting p62-NRF2-GPX4 Ferroptosis Axis.
Chen X, Jiang R, Chu Y, Sun Y, Yuan Z, Qian Y, Cheng X, Dong H
Advanced biology 2026 Feb;10(2):e00580
Advanced biology 2026 Feb;10(2):e00580
Environmentally relevant lanthanum chloride exposure induces hepatic steatosis in zebrafish larvae via PPARα-dependent ApoB suppression.
Li K, Zhao X, Xie Z, Wu Q, Jia W, Zhou X, Gao X, Zeng P, Li J, Niu Q, Qi Z, Cui M, Song W
Communications biology 2026 Feb 9;9(1)
Communications biology 2026 Feb 9;9(1)
LncRNA AC098613.1 promotes acute myeloid leukemia cell differentiation through CDC5L/ADAP1/NRD1 axis.
Jiang Q, Wang X, Yao H, Wang J, Tang P, Liang M, Pan Z, Li B, Lin C, Wu Q, Wang Q, Zheng Q, Kuok CF, Liu H, Sun C, Li D
Apoptosis : an international journal on programmed cell death 2026 Feb 9;31(2):67
Apoptosis : an international journal on programmed cell death 2026 Feb 9;31(2):67
ZP3 promotes hepatocellular carcinoma progression via the Notch signaling pathway and is associated with the tumor microenvironment and immunotherapy response.
Qu C, Yan X, Li Y
World journal of surgical oncology 2026 Feb 9;24(1)
World journal of surgical oncology 2026 Feb 9;24(1)
Wnt/β-Catenin Activation by iCRT3 Enhanced the Pluripotency of Bovine Expanded Pluripotent Stem Cells.
Liu D, Qu B, Wang J, Han X, Su M, Li X, Li Y, Li X
Animals : an open access journal from MDPI 2026 Feb 9;16(4)
Animals : an open access journal from MDPI 2026 Feb 9;16(4)
Liver-muscle metabolic crosstalk: xanthosine as a key effector of broiler myogenesis.
Chen Y, Ding C, Ren M, Li Z, Liu S, Sun H, Yu S, Niu Q, Li X, Li B, Li L, Yang X, Sun Q
Journal of animal science and biotechnology 2026 Feb 8;17(1):24
Journal of animal science and biotechnology 2026 Feb 8;17(1):24
Danggui-Baishao herb pair protects against dextran sulfate sodium-induced colitis by modulating the Wnt/β-catenin pathway.
Xu T, Hou WX, Yang ST, Shao YP, Wang J, Han TT, Li JN
World journal of gastroenterology 2026 Feb 7;32(5):113024
World journal of gastroenterology 2026 Feb 7;32(5):113024
FSHR-targeting tetrahedral DNA frameworks ameliorate ovarian aging through oxidative stress elimination.
Dai Y, Guo Y, Chen D, Li P, Xue L, Feng Y, Tang W, Wu C, Wei S, Dai J, Jiang D, Wang S, Wu M
Journal of nanobiotechnology 2026 Feb 7;24(1)
Journal of nanobiotechnology 2026 Feb 7;24(1)
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Gui S, Yu W, Song Z, Peng L, Luo H, Huang K, Xiao J, Xie J, Cai S, Yuan S, Tao Z, Cheng Z
Cell death & disease 2026 Feb 7;17(1):208
Cell death & disease 2026 Feb 7;17(1):208
Antitumor efficacy and molecular mechanism of lenvatinib combined with vitamin K2 against hepatocellular carcinoma.
Zhang Y, Chen D, Qian X, Long C, Zheng Z
World journal of surgical oncology 2026 Feb 6;24(1)
World journal of surgical oncology 2026 Feb 6;24(1)
Molecular basis of collagen galactosylation by GLT25D1.
Sun H, Zhang M, Shi Y, Zhang D, Hua Z, Yang P, Yang Y, Li J, Chen J, Wang C, Li P, Hu X, Ke Y, Zhang M, Liu X, Yu H
Nature communications 2026 Feb 6;17(1)
Nature communications 2026 Feb 6;17(1)
Comprehensive Proteomics and β-Hydroxybutyrylation Profiling in Starvation-Induced Gastrocnemius Muscle Remodeling.
Cui L, Huang C, Su Y, Xu S, Zha L, Zhao Q, Quan W, Lan X, Xiang Y, Wang Q
Biology 2026 Feb 6;15(3)
Biology 2026 Feb 6;15(3)
Single-cell profiling reveals pervasive heterogeneity in subcellular RNA localization.
Fan X, Hafner M
bioRxiv : the preprint server for biology 2026 Feb 6;
bioRxiv : the preprint server for biology 2026 Feb 6;
Discovery of novel small molecule inhibitor targeting the tumor promoting effect of transcription factor PLAGL2.
Ding Y, Wang Z, Xia X, Wang J, Li Z, Gu C, Hao C, Xu K, Gao M, Yin H, Chen S, Gong X, Zhou W, Zhang M, Yang Y, Zhang D, Dai B, Zhang M
European journal of medicinal chemistry 2026 Feb 5;303:118471
European journal of medicinal chemistry 2026 Feb 5;303:118471
Chicory Extract Alleviates Anthracycline-Induced Cardiotoxicity by Inhibiting Mitochondrial Damage via the UCP2/NLRP3 Pathway.
Rao Y, Wang Y, Liu Y, Huang J, Ding X, Lin Z, Zhang B, Zhang X
International journal of molecular sciences 2026 Feb 5;27(3)
International journal of molecular sciences 2026 Feb 5;27(3)
Astrocytic CCL5 orchestrates CCR5-positive neuronal necroptosis in subarachnoid hemorrhage.
Chen P, Jiang YH, Xue SQ, Wang Y, Lin WL, Shi MY, Li SJ, Sun WW, Zhao JX, Kang DZ, Ye ZC, Lin QS
Journal of neuroinflammation 2026 Feb 5;23(1)
Journal of neuroinflammation 2026 Feb 5;23(1)
Absence of Neuromuscular Dysfunction in Mice with Gut Epithelium-Restricted Expression of ALS Mutation hSOD1(G93A).
Dong L, Li X, Li A, Yi J, Vockery Y, Chang Y, Pan Z, Brotto M, Zhou J
Biomolecules 2026 Feb 5;16(2)
Biomolecules 2026 Feb 5;16(2)
Targeting Hsp70 triggers ferroptosis: a novel anti-cancer mechanism of a marine natural product in prostate cancer.
Liu Q, Cong M, Gao C, Liu Y, Wang J, Wang X
Natural products and bioprospecting 2026 Feb 5;16(1):34
Natural products and bioprospecting 2026 Feb 5;16(1):34
Uncovering a Glaucoma-Linked Lysophosphatidic Acid-MAPK/AP-1 Fibrosis Axis in Human Trabecular Meshwork Cells and Its Modulation by Diospyros kaki Leaf Extract.
Jeon Y, Kwon H, Ahn HR, Huh G, Kim T, Park YT, Park HB, Jeong JH, Jo JH, Kim YJ, Jung SH
International journal of molecular sciences 2026 Feb 4;27(3)
International journal of molecular sciences 2026 Feb 4;27(3)
EP300 promotes hepatocellular carcinoma proliferation, migration and in vivo tumorigenicity revealed by integrated experimental and bioinformatic analyses.
Liu Z, Wang J, Wu X, Shi H, Ding Y, Liu X
Journal of translational medicine 2026 Feb 4;24(1)
Journal of translational medicine 2026 Feb 4;24(1)
Macrophage-Mimicking Biomimetic Microbubbles for Early Ultrasound Molecular Imaging of Acute Rejection in Heart Transplantation.
Wang C, Li G, Chen J, Liu C, Liu Y, Ai X, Yang Y, Leng X, Wang Z, Jiang S
ACS applied materials & interfaces 2026 Feb 4;18(4):6639-6655
ACS applied materials & interfaces 2026 Feb 4;18(4):6639-6655
Dysregulated expression of the tumor suppressor p14ARF in cancer provides an effective target for TCR-T cell therapeutics.
Schmitt TM, Furiya K, Black C, Vazquez A, Sharma J, Hailemariam M, Paushter DH, Trieu L, Lam J, Lee B, Rakhra K, Whalen KA, Mehta NK, Sauer K, Baeuerle PA, Michaelson JS, Greenberg PD, Chapuis AG
Journal for immunotherapy of cancer 2026 Feb 4;14(2)
Journal for immunotherapy of cancer 2026 Feb 4;14(2)
SMYD3 synergises with RACK1 to promote colorectal cancer lung metastasis by recruiting SMAD3.
Bai X, Han D, Chen J, Sheng S, Feng H, Wang H, Xu K, Huang Y, Huang M, Chu X, Chen Y, Lei Z
Cell communication and signaling : CCS 2026 Feb 3;24(1)
Cell communication and signaling : CCS 2026 Feb 3;24(1)
Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics.
Kumari B, Damodaran AP, Guiblet WM, Xiao MS, Behera AK, On TA, McIntosh CE, Teszler M, Holloway C, Le S, Parab N, Zhao Y, Aregger M, Gonatopoulos-Pournatzis T
Nature communications 2026 Feb 3;17(1):1218
Nature communications 2026 Feb 3;17(1):1218
The Mislocalization of TDP-43 to Mitochondria Impairs Myotube Maturation.
Wan Y, Yu Z, Yang J, Zhang W, Yu M, Meng L, Wang Z, Yuan Y, Ruan L, Deng J, Wang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71603
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71603
Resveratrol and AG490 Overcome Glioblastoma Cells' Resistance to Monotherapy by Inhibiting JAK2/STAT3 Signalling Pathway.
Ullah A, Han C
Cancers 2026 Feb 28;18(5)
Cancers 2026 Feb 28;18(5)
Combinatorial treatment with donafenib and quercetin suppresses lipid metabolism in HepG2 cells by targeting the CREB1/DRP1/SREBP1 axis.
Xiang L, Shi J, Huang X, Zhou S
Translational cancer research 2026 Feb 28;15(2):97
Translational cancer research 2026 Feb 28;15(2):97
Identification and validation of a novel estrogen-related model for breast cancer to predict the prognosis.
Xia M, Dong S, Cao J, Wang J, Wang C
Translational cancer research 2026 Feb 28;15(2):107
Translational cancer research 2026 Feb 28;15(2):107
LncSMIM14 Hijacks Rab3a-Mediated Endocytosis to Promote Bovine Viral Diarrhea Virus Replication.
Shao Z, Ma S, Gao F, Lou Y, Liu X, Yang L, Mai Z, Wang L, Haiyilati A, Shi H, Fu Q
International journal of molecular sciences 2026 Feb 27;27(5)
International journal of molecular sciences 2026 Feb 27;27(5)
UHRF2 related to sumoylation : assessment of its role in immune suppression and therapeutic potential in colorectal cancer.
Huang M, Qin Y, Yang Q, Chen X, Chen K
BMC cancer 2026 Feb 27;26(1)
BMC cancer 2026 Feb 27;26(1)
Matrix Metalloproteinase 7 Mediates Epithelial-Mesenchymal Transition to Promote Liver Fibrosis Through E-cadherin/β-catenin Pathway in Biliary Atresia.
Rong L, Tang J, Li X, Zhang M, Chi S, Zhou Y, Zhang X, Cao G, Li Y, Tang S
International journal of molecular sciences 2026 Feb 26;27(5)
International journal of molecular sciences 2026 Feb 26;27(5)
Synergistic Effects of Nutritional Formula on Joint Inflammation Through Modulation of Bone Metabolism in Rats.
Wang H, Wang Y, Fan D, Niu Z, Su H, Li A, Kou R, Yue Z, Wu S, Lv H, Ji X, Hu Y, Zhao Y, Wang S
Nutrients 2026 Feb 26;18(5)
Nutrients 2026 Feb 26;18(5)
DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312.
Fu Y, Xiang Y, Han Y, Cai J, Duan S, Chen A, Dong Z
Nature communications 2026 Feb 26;17(1)
Nature communications 2026 Feb 26;17(1)
USP30-AS1 functions as a post-transcriptional amplifier of interferon signalling to drive autoimmune pathogenesis.
Pan J, Feng MY, Xia T, Jiang S, Zhu PP, Yu XP, Su ZH, Liu Y, Wu JQ, Zhao M, Li T, Xue W, Yu Y, Chen L, Cai H
Cell & bioscience 2026 Feb 26;16(1)
Cell & bioscience 2026 Feb 26;16(1)
Enolase 1 suppresses influenza A virus replication by blocking the nuclear import of the viral ribonucleoprotein complex.
Kong X, Liu J, Zhu Q, Xu S
Cellular and molecular life sciences : CMLS 2026 Feb 25;83(1)
Cellular and molecular life sciences : CMLS 2026 Feb 25;83(1)
The SIRT1-Mediated p53 Deacetylation Pathway Modulates Apoptosis and Promotes Viral Replication in MVC-Infected Cells.
Yan Y, Ren X, Xiao Y, Li F, Guo J, Ji K, Hei Z, Zhang Z, Sun Y
Pathogens (Basel, Switzerland) 2026 Feb 25;15(3)
Pathogens (Basel, Switzerland) 2026 Feb 25;15(3)
Irisin inhibits adipogenic differentiation of bone marrow mesenchymal stem cells through the SIRT1/RANBP2/FTO signaling axis and protects against osteoporosis.
Chen J, Liu J, Fu Q, Xu M, Zhai X, Li L, Xu W, Wu X, Wang K, Si H
Cell death discovery 2026 Feb 25;12(1)
Cell death discovery 2026 Feb 25;12(1)
Triptonide Suppresses AML via PI3K/AKT Signaling: A Network Pharmacology Approach Validated by Molecular Docking and Experimental Studies.
Song L, Meng J, Li H, Fu W, Hong K, Shen S, Zhang Z, Ding S, Li S, Zhang Z, Bei W, Huo H, Tan Y, Sui F, Liu L
Current issues in molecular biology 2026 Feb 24;48(3)
Current issues in molecular biology 2026 Feb 24;48(3)
Identifying the hub genes in macrophage infiltration and verifying of the role of VSIG4 in IgA nephropathy.
Tang L, Xu Y, Nong Z, Li F, Pan L
Scientific reports 2026 Feb 23;16(1)
Scientific reports 2026 Feb 23;16(1)
PDHA1 enhances resistance to ferroptosis in anoikis-resistant prostate cancer by upregulating AIFM2.
Cong Y, Chen K, Ju Y, He Q, Liu C, Chen J, Lv F, Chen J, Li H, Chen L, Song Y
Cell death discovery 2026 Feb 23;12(1)
Cell death discovery 2026 Feb 23;12(1)
Multi-omics analysis reveals RBPJ-mediated regulation of EGF/ACTN2/MYPN/COL21A1 in fibroblast during oviduct functional remodeling of duck.
Niu Y, Zhang Y, Fa C, Qian X, Wang Z, Zhou X, Yu H, Zhao A, Du X
Poultry science 2026 Feb 22;105(6):106688
Poultry science 2026 Feb 22;105(6):106688
[Xuebijing Injection in synergy with linezolid alleviates inflammatory injury in mice with MRSA pneumonia by inhibiting the Hla-NLRP3 pathway].
Yin M, Li R, Yang K, Jiao W, Liu X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):412-422
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):412-422
Transcriptomics and functional genomics implicate WNT3 in hemispheric lateralization of speech production.
Wang Z, Chen Y, Feng Y, Zu G, Wang W, Liang L, Liu X, Mei Y, Yang J, Wang T, Liu M, Jiang L, Snell RG, Highet B, Curtis M, Chen L, Li SB, Wu J, Zhang M, Li W, Wei GH, You L
iScience 2026 Feb 20;29(2):114692
iScience 2026 Feb 20;29(2):114692
ACTG1 facilitates proliferation and epithelial-mesenchymal transition-mediated metastasis via COL21A1 in gastric cancer.
Li S, Lan B, Pan L, Sun M, Cui M, Huang Y, Wei S, Huang H
iScience 2026 Feb 20;29(2):114666
iScience 2026 Feb 20;29(2):114666
p300 upregulates I kur in atrial cardiomyocytes through activating NLRP3 inflammasome in hypertension.
Zeng L, Liu P, Rao F, Du Z, Xiao H, Yu S, Deng C, Zhang M, Liu F, Zhu R, Deng H, Wu S, Xue Y, Fang X, Wei W
Chinese medical journal 2026 Feb 20;139(4):576-588
Chinese medical journal 2026 Feb 20;139(4):576-588
Radix Rehmanniae Preparata polysaccharide promoted zebrafish heart regeneration by activating the IFN-γ/NF-κB signaling axis.
Yan Y, Tao K, Xie H, Zhou H, Wu Q, Pu S, Li D, Guo Z, Zhou Z, Xu S
Biology direct 2026 Feb 2;21(1)
Biology direct 2026 Feb 2;21(1)
Research on the mechanism of CRMP4-mediated cytoskeletal actin polymerization in promoting invasive migration of stromal cells in endometriosis.
Song L, Guo J, Yin L, Guo H, Ji G, Zhang Y, Hu R
Journal of translational medicine 2026 Feb 19;24(1)
Journal of translational medicine 2026 Feb 19;24(1)
Growth differentiation factor 15 promotes the malignant progression of multiple myeloma via activation of PI3K/Akt/NF-κB signaling pathway.
Fan H, Wu Y, Peng Y, Wang L, Tu S, Peng H, Yang J, Li X, Shi Z, Li M, Song K
Journal of translational medicine 2026 Feb 17;24(1)
Journal of translational medicine 2026 Feb 17;24(1)
VDAC1 protein derived from extracellular vesicles promotes paclitaxel resistance in gastric cancer through autophagy and mitophagy.
Bi Y, Wei S, Zhang Z, Wang Y, Wen Y, Wang H, Li K, Zhang C, Wang Y, Zhao L, Sun G
Cancer biology & medicine 2026 Feb 17;23(2):252-75
Cancer biology & medicine 2026 Feb 17;23(2):252-75
CircRNA-TMEM71 Inhibits Human Aortic Smooth Muscle Cell Ferroptosis and Prevents Aortic Dissection Formation Through IGF2BP3-Mediated Stability of FSP1.
Zhu L, He C, Shi H, Shao G, Sun L
Journal of the American Heart Association 2026 Feb 17;15(4):e043108
Journal of the American Heart Association 2026 Feb 17;15(4):e043108
IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer.
Ren T, Chen X, Wang X, Xu Y, Shao N
Journal of experimental & clinical cancer research : CR 2026 Feb 16;45(1)
Journal of experimental & clinical cancer research : CR 2026 Feb 16;45(1)
Marine trichodermamide B inhibits prostate cancer progression via catalase inhibition-induced apoptosis.
Fang W, Chen C, Nie M, Liu Q, Huang T, Gao C, Liu Y, Zhou X, Wang X
Cell communication and signaling : CCS 2026 Feb 16;24(1)
Cell communication and signaling : CCS 2026 Feb 16;24(1)
Cu(OH)(2) nanopesticide induced adolescent social behavior deficits via long noncoding RNA-mediated synaptic network dysfunction.
Ren Z, Duan Y, Ren M, Cai Y, Liang J, Wang X, Sun J, Ren D, Ku T, Ning X, Sang N
Journal of hazardous materials 2026 Feb 15;504:141294
Journal of hazardous materials 2026 Feb 15;504:141294
USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression.
Haowei Z, Li X, Liao W, Qin X, Jiang Y, Yang H, Zeng H, Li Y, Xie W, Zhang Y, Xu N
Cell death & disease 2026 Feb 14;17(1):225
Cell death & disease 2026 Feb 14;17(1):225
Y chromosome-linked EIF1AY deletion drives sex differences in multiple myeloma.
Feng Z, Bai J, Li Y, Li L, Zhang L
NPJ precision oncology 2026 Feb 14;10(1)
NPJ precision oncology 2026 Feb 14;10(1)
Metamorphosing macrophages promote placental fibrosis by upregulating the transcription factor STAT5A.
Chen A, Huang X, Liao E, Shao Y
Journal of translational medicine 2026 Feb 13;24(1)
Journal of translational medicine 2026 Feb 13;24(1)
African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation.
Fan J, Yang J, Tian Z, Zhang X, Geng S, Luo J, Boldogh I, Zeng Q, Yin H, Guan G, Niu Q
Journal of molecular cell biology 2026 Feb 13;17(7)
Journal of molecular cell biology 2026 Feb 13;17(7)
Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression.
Luo Z, Xu G, Li C, Sun Z, Chen H, Yang M, Ye Y, Chen Q, Xu B, Luo H, Sun B
Journal of medicinal chemistry 2026 Feb 12;69(3):3457-3476
Journal of medicinal chemistry 2026 Feb 12;69(3):3457-3476
Targeting ADAMTS1/HDAC6 alleviates TGF-β1/SMAD2-associated cardiac fibrosis in cardiac fibrosis post-myocardial infarction.
Jin Q, Chen C, Wu P, Li L, Jiang L, Chen R, Xu S, Huang Y, Xu H, Long X
Cell biology and toxicology 2026 Feb 12;42(1)
Cell biology and toxicology 2026 Feb 12;42(1)
Supplemental exposure to polystyrene nanoplastics synergistically amplifies calcium oxalate crystal-induced injury to renal tubular epithelium, accelerating the formation of calcium oxalate kidney stones.
Su X, Yang Y, Xiang H, Dong C, Shi M, Wang Y, Zhou Q, Song Q, He Z, Jiang Q, Chen B, Wang Y, Xiong Y, Yang S
Particle and fibre toxicology 2026 Feb 12;23(1)
Particle and fibre toxicology 2026 Feb 12;23(1)
Fungal-Bacterial Crosstalk Modulates Glucocorticoid-Primed TLR2 Signaling in the Human Skin.
Cho O, Watanabe K, Sugita T
Microorganisms 2026 Feb 12;14(2)
Microorganisms 2026 Feb 12;14(2)
Self-assembling ferritin nanoplatform enables amyloid-β-targeted immunotherapy and cognitive rescue in APP/PS1 mice.
Liu J, Zhang C, Zhao L, Liu R, Cao T, Zhang D, Liu Z, Sun D, Zhang Y, Yu X, Kong W, Wu H
Brain, behavior, and immunity 2026 Feb 12;135:106486
Brain, behavior, and immunity 2026 Feb 12;135:106486
A CDK-4EBP1 signaling axis drives HSV-1 replication and underscores a druggable pathway for potent antiviral intervention.
Madavaraju K, Yadavalli T, Singh SK, Patil CD, Borase H, Shukla D
mBio 2026 Feb 11;17(2):e0374125
mBio 2026 Feb 11;17(2):e0374125
Gasdermin B-mediated pyroptosis as a host defense against swine enteric coronaviruses and its antagonism by PEDV.
Yao Y, Huang N, Huang X, Yuan M, Kang L, Ma Y, Han J, Zhang G, Liu P
mBio 2026 Feb 11;17(2):e0290425
mBio 2026 Feb 11;17(2):e0290425
Early HMGB1 Inhibition Reduces Hippocampal Injury During Adolescence in a Young Mouse Model of Radiation-Induced Brain Injury.
Sun Y, Shi M, Ma L, Xie H, Hei M, Zuo W
Cellular and molecular neurobiology 2026 Feb 10;46(1)
Cellular and molecular neurobiology 2026 Feb 10;46(1)
PUF, a biflavone monomer, triggers DNA damage through SLC25A15 downregulation and purine metabolic suppression in DLBCL.
Su C, Lu G, Ou L, Liang L, Wang C, He Y, Zeng R, Li Y, Zhou H, Xiao L
Journal of translational medicine 2026 Feb 10;24(1)
Journal of translational medicine 2026 Feb 10;24(1)
Importin Alpha Is Implicated in the Nuclear Import of Novel Duck Reovirus Protein p18.
Wang D, Song J, Wang J, Guo F, Quan R
Viruses 2026 Feb 10;18(2)
Viruses 2026 Feb 10;18(2)
LSKL mitigates dehydroepiandrosterone-induced apoptosis and oxidative stress by THBS1/PI3K/AKT pathway in rat granulosa cells.
Zhang L, Wang C, Liu Y, Wang X, Li S, Zhang H, Zhang X, Wang Y, Zhang Y, Liu L, Liu M
Life sciences 2026 Feb 1;386:124156
Life sciences 2026 Feb 1;386:124156
Adiponectin Receptor 1-vascular endothelial growth factor axis mediates resistance to epidermal growth factor receptor-targeted therapy in nasopharyngeal carcinoma.
Cheng Z, Peng X, Wu S, Li W, Liu X, Zhang G
Anti-cancer drugs 2026 Feb 1;37(2):146-156
Anti-cancer drugs 2026 Feb 1;37(2):146-156
Botulinum neurotoxin A alleviates Deinagkistrodon acutus venom-induced limb injury through promoting macrophage polarization in rabbits.
Xie L, Wu H, Lai L, Du W, Xu J, Lan P
Toxicon : official journal of the International Society on Toxinology 2026 Feb 1;270:108936
Toxicon : official journal of the International Society on Toxinology 2026 Feb 1;270:108936
Pregnane X receptor mitigates aristolochic acid-induced acute kidney injury via p53 ubiquitination.
Liu Q, Deng F, Chen A, Liu Y
Renal failure 2026 Dec;48(1):2630492
Renal failure 2026 Dec;48(1):2630492
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
Liu L, Gao M, He W, Wang M, Zhou S, Wang X, Shu Y
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
LncRNA UNC5C-AS1 inhibits angiogenesis and induces endothelial apoptosis via the miR-148a-3p/EMP1 axis in preeclampsia.
Wang Y, Gao Y, Liu L, Ma K, He Y, Qi H, Zhang X
Cell adhesion & migration 2026 Dec;20(1):2622820
Cell adhesion & migration 2026 Dec;20(1):2622820
HIV-1 Vpr activates microglia by upregulating m6A modification through ubiquitin-proteasome pathway-mediated degradation of the demethylase ALKBH5.
Peng Q, Li W, Qian F, Zhu Y, Hu S, Shi Y, Xia Y, Liu W, Shu X, Wan P, Liu Y, Sun B
Virulence 2026 Dec;17(1):2645908
Virulence 2026 Dec;17(1):2645908
Super-enhancer-associated miR-1260b coordinates adipogenesis and metabolic programming in human adipose stem cells.
Li S, Ji S, Yu Z, Liu H, Wu J
Adipocyte 2026 Dec;15(1):2638071
Adipocyte 2026 Dec;15(1):2638071
Gut microbiota dysbiosis exacerbates acute pancreatitis via Escherichia coli-driven neutrophil heterogeneity and NETosis.
Zou Y, Li N, Li X, Kuang M, Xu X, Guan L, Li X, Zheng P, Li L, Wan J, Lu N, Liu J, He C, Zhu Y
Gut microbes 2026 Dec 31;18(1):2606480
Gut microbes 2026 Dec 31;18(1):2606480
Engineered extracellular vesicles from human placental mesenchymal stem cells attenuate abdominal aortic aneurysm formation by inhibiting Nat10-mediated vascular smooth muscle cell senescence.
Jia X, Hu X, Fu Z, Zhang L, Luo X, Huang W, Hua Y, Fang Q, Zeng J, Huang F, Wei G, Bin J, Zheng H, Chen G, Huang S
Biomaterials 2026 Aug;331:124109
Biomaterials 2026 Aug;331:124109
Organelle stress in pyometra: Molecular evidence of endoplasmic reticulum stress and mitochondrial dysfunction.
Zhao W, Deng X, Tang J, Li S, Hu B
Theriogenology 2026 Aug;260:117919
Theriogenology 2026 Aug;260:117919
PHC2 promotes hepatocellular carcinoma progression and serves as a robust prognostic biomarker: A pancancer multiomics and clinical validation study.
Wang Q, Ye Y, Qin S, Luo M, Yang J, Zhang M
Cellular signalling 2026 Aug;144:112555
Cellular signalling 2026 Aug;144:112555
B4GALT1 drives osteoarthritis progression by stabilizing IL-1R1 through N-linked glycosylation.
Ma W, OuYang D, Xu Z, Luo W, Tian G, Jiang N, Liu C, Zhang R, Yu Q
Cellular signalling 2026 Aug;144:112541
Cellular signalling 2026 Aug;144:112541
KLK8 promotes cartilage degradation and pyroptosis in osteoarthritis by activating the NF-κB and NLRP3 inflammasome pathways.
Xu L, Jiang Z, Li H
Tissue & cell 2026 Aug;101:103427
Tissue & cell 2026 Aug;101:103427
Diosgenin alleviates hepatic fibrosis via PI3K/Akt/mTOR mediated fatty acid metabolic reprogramming and NF-κB activation.
Shi Y, Zhang Y, Liu D, Xiang S, Liang S, Lin W, Li S, Zhai X, Cheng B
Journal of ethnopharmacology 2026 Aug 10;367:121747
Journal of ethnopharmacology 2026 Aug 10;367:121747
Aberrant histone acetylation and dysregulated synaptic plasticity in cognitive impairment induced by a high-methionine diet.
Li J, Fu Y, Gu X, Xie Q, Liu Z, Cao Z, Li L, Ren J, Li Y, Yang H, Peng Z, Liu Z, Xie J
Neural regeneration research 2026 Aug 1;21(8):3842-3853
Neural regeneration research 2026 Aug 1;21(8):3842-3853
Integrated multi-omics analysis identifies potential therapeutic targets for Alzheimer's disease.
Li H, Kang J, Liang Z, Wang X, Zhu L, Tang H, Peng W
Neural regeneration research 2026 Aug 1;21(8):3769-3778
Neural regeneration research 2026 Aug 1;21(8):3769-3778
Shh-S100A10 axis curbs neuronal PANoptosis after ischemic stroke.
Wang L, Tang H, Wen J, Yang Q, Huang J, Zhao Y, Ren Y, Yang Q
Neural regeneration research 2026 Aug 1;21(8):3579-3587
Neural regeneration research 2026 Aug 1;21(8):3579-3587
Quercetin targeted NF-κB to regulate platelet activation and prevent arterial thrombosis.
Wang W, Li Y, Liu Y, Sun Z, Zhao B, Song F
Tissue & cell 2026 Apr;99:103270
Tissue & cell 2026 Apr;99:103270
Three-dimensional cell culture in vitro could better recapitulate the biological behavior of cells in vivo.
Qi Z, Yang S, Fu C, Xu J, Li Q, Yan J, Shen A, Hu B
Tissue & cell 2026 Apr;99:103246
Tissue & cell 2026 Apr;99:103246
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
Wang MS, Zhou HF, Li H, Gao LN, Feng Y, Zhu H
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
MFG-E8 prevents M1 macrophage polarization to alleviate osteoarthritis by inhibiting NLRP3 inflammasome.
Chen Q, Shi H, Qu H, Feng J, Gao Y, Wang Z, Long R, Yang Z
Cytotechnology 2026 Apr;78(2):68
Cytotechnology 2026 Apr;78(2):68
USP16 promotes M2 polarization of macrophages in colorectal cancer by activating the Notch pathway via inducing the deubiquitination of E2F1.
Yu H, Chen M, Chen B, Hu S, Dai X
Cytotechnology 2026 Apr;78(2):66
Cytotechnology 2026 Apr;78(2):66
Anacardic Acid Inhibits Pde2a to Enhance Colonic Epithelial Barrier Integrity in the Improvement of Diabetic Cardiomyopathy.
Ge R, Yin J, Meng H, Huang X, Sun L, Zheng Y, Yang J, Wu H
Molecular nutrition & food research 2026 Apr;70(8):e70464
Molecular nutrition & food research 2026 Apr;70(8):e70464
Construction and validation of golgi apparatus-related genes as predictors of the immune microenvironment and prognosis in colorectal cancer.
Chen J, Wang F
Translational oncology 2026 Apr;66:102714
Translational oncology 2026 Apr;66:102714
TMEM44 as a Novel Prognostic Marker for Hepatocellular Carcinoma is Associated with Tumor Invasion, Migration, and Apoptosis.
Wu Z, Qiu B, Liu S, Hong Y, Sun L, Yin X, Huang Y, Chen Z
Biochemical genetics 2026 Apr;64(2):2764-2781
Biochemical genetics 2026 Apr;64(2):2764-2781
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
Yang Z, Zeng A, Yu B, Xie C, Zhu W, Liu H, Gu C, Fu M
Biochemical genetics 2026 Apr;64(2):2416-2447
Biochemical genetics 2026 Apr;64(2):2416-2447
A Novel Telomere Maintenance Gene-Related Model for Prognosis Prediction in Gastric Cancer.
Wang KL, Xi XX, Zheng JH
Biochemical genetics 2026 Apr;64(2):2290-2312
Biochemical genetics 2026 Apr;64(2):2290-2312
Oncogenic role and potential mechanisms of MYO1B in breast cancer.
Dai M, Jiang Q, Zhang D, Li L
In vitro cellular & developmental biology. Animal 2026 Apr;62(4):428-443
In vitro cellular & developmental biology. Animal 2026 Apr;62(4):428-443
The glycolytic metabolite phosphoenolpyruvate restricts cGAS-driven inflammation to promote healthy aging.
Song Z, Hu H, Zhang W, Zheng X, Liang L, Zhao B, Song G, Li J, Li S, Wen Y, Zhang B, Wang W, Deng G, Zhang C, Jiang H, Hu S, Tu H, Wu M, Li H
Nature aging 2026 Apr;6(4):831-848
Nature aging 2026 Apr;6(4):831-848
Soluble Sema4D From γδ T Cells Exerts Osteoblast Inhibition via Plexin-B/mTOR Signalling Contributing to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws.
Ou L, Qiao S, Liao Z, Tan X, Huang H, Zhou Z, Luo R, Zeng W, Yang Y, Zhang Z, Chen J, Wang S, Jiang Y, Hao J, Shen Y, Shao L
Cell proliferation 2026 Apr;59(4):e70114
Cell proliferation 2026 Apr;59(4):e70114
An intelligent nanoliposome alleviates disc degeneration and discogenic pain by inhibiting neurovascular ingrowth via a "Soil-conditioning, seed-modulating, and weeds-suppressing" strategy.
Li F, Shi Y, Liu J, Yang Y, Yan C, Sun X, Zhang Z, Zhang B, Wang Q, Du M, Wang Z, Sun J, Xu X, Sun K, Sun J, Wang Y, Shi J
Bioactive materials 2026 Apr;58:157-182
Bioactive materials 2026 Apr;58:157-182
POSTN(+) fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling.
Zhang C, Chen S, Qian C, Lv W, Zhang Q, Wang Y, Wu Y, Liu X
Oncology reports 2026 Apr;55(4)
Oncology reports 2026 Apr;55(4)
MRPL42 Knockdown Suppresses the Malignant Functions of Hepatocellular Carcinoma by Regulating Oxidative Phosphorylation.
Lv J, Gan FY, Li MH, Yin QJ
Current medical science 2026 Apr;46(2):483-495
Current medical science 2026 Apr;46(2):483-495
UXS1 Knockdown Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma by Inducing Ferroptosis via SLC7A11/GPX4 Pathway.
Lv J, Han K, Gan FY, Li MH, Yin QJ
Current medical science 2026 Apr;46(2):472-482
Current medical science 2026 Apr;46(2):472-482
KAT8: A Promising Biomarker for the Prognosis of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure.
Wang X, Wang W, Huang L, Yang Y, Lu W, Wu Y, Xu M, Chen Y
Journal of gastroenterology and hepatology 2026 Apr;41(4):1244-1253
Journal of gastroenterology and hepatology 2026 Apr;41(4):1244-1253
NUPR1 and LCN2: Potential Therapeutic Targets for Colorectal Cancer Via Modulating Cell Viability, Migration, and Ferroptosis-Related Pathways.
Luo D, Luo X, Qian S, Liu J
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70809
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70809
Graphene oxide coating on two-dimensional glass substrates and three-dimensional zirconia scaffolds for bone tissue regeneration.
Liu K, Tian Y, Mu R, Wang X, Xin M, Ding H, Qian Y, Hu Z, Zeng C, Wei X, Shuai Y, Jin L
Materials today. Bio 2026 Apr;37:102852
Materials today. Bio 2026 Apr;37:102852
Biomimetic cancer cell membrane-coated liposomal nanocarriers loaded with silibinin suppress gastric cancer progression via SNHG1/miR-383-5p/HSP90AA1 axis-mediated PI3K/AKT pathway inhibition.
Yao J, Sun Q, Zhang X, Yang D, Wu H, Hu Z, You Q, Wei Z, Wang W
Materials today. Bio 2026 Apr;37:102744
Materials today. Bio 2026 Apr;37:102744
CircRNA SLAIN1 is associated with reduced malignancy progression of glioblastoma and the M2-like polarization of tumor-associated macrophages via miR-1225-3p/NLRX1 axis.
Ai M, Li F, Huang Z, Liu C, Liao H, Huang X, Li Z, Wang B, Zhang C, Xu A, Lin J, Xu R, Yuan Y, Tian Y
International journal of biological macromolecules 2026 Apr;357:151212
International journal of biological macromolecules 2026 Apr;357:151212
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Li X, Ye J, Zhong D, Xie J, Ding Z, Zhou M
Biomaterials 2026 Apr;327:123767
Biomaterials 2026 Apr;327:123767
Dynamic regulation of K33- and K48-linked ubiquitination of Tip60 by TRIM37 orchestrates host DNA damage response during Pseudomonas aeruginosa infection and recovery.
Yu H, Wang X, Xiong J, He X, Ma C, Wang Q, Chen R, Li Y, Dai Q, Min Q, Zhou J, Zhang K
Microbiological research 2026 Apr;305:128414
Microbiological research 2026 Apr;305:128414
Landscape of splicing factors in early-onset gastric cancer reveals SRSF1 as a key driver of oxaliplatin resistance.
Zhong B, Xiong Z, Xu H, Zheng J, Mohamed SA, Sun J, Huang D, Deng Z, Guo J, Peng J, Chen Y, Lian L
The Journal of biological chemistry 2026 Apr;302(4):111279
The Journal of biological chemistry 2026 Apr;302(4):111279
Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4-Mediated Ferroptosis.
Ren J, Wu S, Su T, Li H, Ding J, Chen F, Mo J, Li J, Wang Z, Han L, Wu Z
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14973
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14973
FTO mediates m6A demethylation of HNF1A and drives hepatic steatosis in metabolic dysfunction-associated steatotic liver disease.
Tan J, Shi C, Wang G, Zhang L, Li F, Yan G, Jin Y, Ding H, Jiang F, Li X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Apr;1871(3):159732
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Apr;1871(3):159732
Lactobacillus plantarum 1-2-3 Ameliorates the Corticosterone-Induced Fatty Liver Hemorrhagic Syndrome in Laying Hens by Biosynthesizing Gamma-Aminobutyric Acid.
Zhang S, Gao P, Wang Q, Liu S, Okoth S, Zhang M, Ji H, Yan L, Fan W, Song S
Probiotics and antimicrobial proteins 2026 Apr;18(3):4248-4263
Probiotics and antimicrobial proteins 2026 Apr;18(3):4248-4263
Inhibitory effect of Anwulignan on the IL-36R/TLR9 signaling pathway: potential therapeutic role in hepatic fibrosis.
Shang Y, Peng YG, Wang Y, Huo XK, Zhang HL, Hao TN, Ma XC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157931
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157931
Dingxin recipe Ⅲ ameliorates atherosclerosis through stard4-mediated regulation of hepatic lipid metabolism.
Gu Y, Jin Y, Zhao H, Tang J, Li Z, Cheng S, Zhang Y, He P, Han Z, He J, Zhou F, Liu X, Jia Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157924
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157924
3,3'-Diindolylmethane ameliorate obesity-related skeletal muscle atrophy via regulating mitochondrial function.
Zhong Y, Chen S, Pan J, Niu R, Du J, Dong Q, Liu Y, Yao Y, Lin Y, Fang H, Su J, Li X, Zhang Y, Yang G, Wu J, Li J, Liu W, Huang B, Tang J, Zhu W
The Journal of nutritional biochemistry 2026 Apr;150:110223
The Journal of nutritional biochemistry 2026 Apr;150:110223
ANKRD62 Modulates NF-κB Signaling to Promote Proliferation and Migration in UCEC.
Hao C, Li Y, Li Z, Fu L, Lin S
Cancer medicine 2026 Apr;15(4):e71822
Cancer medicine 2026 Apr;15(4):e71822
Cockroach-Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation.
Qin Z, Wu J, Xiao X, Wang X, Ding N, Zhao X, Ma L, Li J, Ma L, Ou C, Ma N, Feng J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22333
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22333
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
Guo S, Chen X, Wang H, Zhou J, Lu P, Liu J, Chai K, Zhang J, Yang S, Lu S, Gao Y, Jin Z, Tao X, Hu Z, Li Q, Wu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis.
Zhang Y, Wang Y, Li B, Li X, Liu C, Chen Y, Tian C, Wang D, Gu X, Jiang C, Wei Y, Ding Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(22):e19563
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(22):e19563
Non-Targeting shRNA-Encoded Plasmid DNA Enhances Protective Immunity Through RIDD-RIG-I Signaling Pathway in the Zika Virus Animal Model.
Huang MS, Liao HC, Peng P, Wu WL, Chai KM, Chen MY, Yu GY, Chuang TH, Chen HW, Chang CR, Liu SJ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e17420
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e17420
Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism.
Li T, Wu J, Zhou SY, Li MA, Zhao LP, Wang A, Song YZ, Huang WY, Tan LL, Qiao CM, Zhao WJ, Cui C, Shen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e16502
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e16502
Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression.
Peng S, Lin W, Li Z, Zhuang R, Peng S, Li B, Chen B, Luo Y, Ou Y, Zhuang W, Du T, Li K, Huang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e08588
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e08588
GATA6 inhibits the periodontitis progression through regulating the Notch signaling pathway.
Li WW, Li QW, Yu J, Sui XN, Wang MM, Yin NN, Liu X
Odontology 2026 Apr;114(2):893-902
Odontology 2026 Apr;114(2):893-902
Regulation of skeletal muscle development and metabolism in broiler chickens by Urolithin A through threonine kinase 1 pathway activation.
Wu L, Peng L, Zhao X
Poultry science 2026 Apr;105(4):106502
Poultry science 2026 Apr;105(4):106502
Discovery, Optimization, and Biological Evaluation of 2-Cyano-2-(9H-xanthen-9-ylidene)acetamide Derivatives as ZNF207 Inhibitors for Anti-Glioma Therapy.
Gao M, Wang J, Wang Y, Li J, Feng J, Gu C, Wang Z, Gong X, Zhou W, Chen S, Xia X, Tang X, Yang Y, Zhang D, Ding Y, Zhang M
Journal of medicinal chemistry 2026 Apr 9;69(7):7594-7641
Journal of medicinal chemistry 2026 Apr 9;69(7):7594-7641
Amentoflavone mitigates UVB-induced epidermal photoaging by antagonizing PAR2-driven PI3K/Akt/FoxO6 oxidative-stress signaling.
Li L, Li Z, Xiao S, Li A, Tian F, Shu P, Gu W
Free radical biology & medicine 2026 Apr 9;251:17-31
Free radical biology & medicine 2026 Apr 9;251:17-31
SEMA4A promotes acute myeloid leukemia progression through inhibiting apoptosis.
Li X, Yao B, Sun M, Li W, Lv X, Luo K, Wu Y, Xiu R, Ma Y, Liu F, Zhao Y, Fan S, Tang L, Fan H
Genes & genomics 2026 Apr 9;
Genes & genomics 2026 Apr 9;
Vps34 Knockdown Alleviated the Long-Term Effect of Nano-Alumina on Cognitive Impairment in Zebrafish When in Embryos.
Zhang Y, Zhao J, Huang T, Gao X, Zhang L, Wang Y, Guo X, Zhang L, Niu Q, Zhang Q
Journal of applied toxicology : JAT 2026 Apr 9;
Journal of applied toxicology : JAT 2026 Apr 9;
Noncanonical open reading frames from lncRNAs encode functional micropeptides that help shape agronomic traits in rice.
Cheng Y, He RR, Jiang J, Yang L, Yuan C, Qin YC, Zhao WL, Mo WT, Liao YH, Chen ZT, Feng JJ, Pang HY, -Cheng Y, Lei MQ, Zhou YF, Lian JP, Zhang YC, Chen YQ
Developmental cell 2026 Apr 8;61(4):919-935.e6
Developmental cell 2026 Apr 8;61(4):919-935.e6
Zuojin Pill ameliorates depression with gastrointestinal dysfunction via Parabacteroides distasonis.
Qiao D, Huang Y, Ge C, Ma M, Gu M, Chen B, Wu Y, Zhao S, Li J, Kang N, Cai Z, Huang S, Tao W, Liu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 8;156:158173
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 8;156:158173
O-GlcNAc Modification Orchestrates HUWE1-Mediated Ubiquitination of TfR1 to Regulate Ferroptosis and Trophoblast Syncytialization in Preeclampsia.
Zhang H, Li M, Zhang J, Sun Q, Jin X, Liu R, Li X, Chen X, Wang A, Luo Z, Shang Y, Kong Y
Free radical biology & medicine 2026 Apr 8;
Free radical biology & medicine 2026 Apr 8;
An Activity-Dependent NEPAS-PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment.
Hu B, Chen Z, Sun B, Gao J, Xu J, Guo X, Gao F, Wang Z, Wu J, Ji X, Liu P, Huang B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 7;:e21069
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 7;:e21069
Mechanisms of Mechanical Stress-Induced Vascular Remodeling via the Lactate-PKM2 Axis and Implications for Microgravity Adaptation.
Li N, Liu L, Wang D, Wang J, Tie Y, Li X, Li J, Gao Y, Yang C, Wang Y
International journal of molecular sciences 2026 Apr 5;27(7)
International journal of molecular sciences 2026 Apr 5;27(7)
Baicalein alleviates Alzheimer's disease pathology in AD models by activating the PI3K/AKT/GSK3β pathway to inhibit neuronal apoptosis.
Cheng W, Yang S, Lu Y, Wang Y, Tan AH
Scientific reports 2026 Apr 4;
Scientific reports 2026 Apr 4;
Identification and Screening of Lactate-Related Genes as Molecular Markers for Early Diagnosis of Steroid-Induced Osteonecrosis of the Femoral Head.
Wang Z, Dong S, Xu K, Tang X, Guo S, Jiang Y, Zhang Y, Li T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71793
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71793
Integration of Single-Cell RNA Sequencing and Machine Learning to Identify and Validate Prognostic Genes With Lymph Node Metastasis and Immune Cell Signatures in Lung Adenocarcinoma.
Lin C, Chen X, Sun Y, Tang X, Jiang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71783
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71783
Chemical-Assisted Ligation-qPCR for Locus-Specific Detection of RNA N(4)-Acetylcytidine and 5-Formylcytidine.
Wang Z, Liu X, Guo X, Xue X, Zhou X, Wang Y
Analytical chemistry 2026 Apr 28;98(16):12133-12141
Analytical chemistry 2026 Apr 28;98(16):12133-12141
Vasoactive intestinal peptide attenuates form-deprivation myopia in guinea pigs by suppressing the Wnt/β-catenin pathway along the retina-choroid-scleral axis.
You Y, Li Q, Yang X, Zou Y, Lu Q, Liao W, Wang H, Li Z, Wu X
Experimental eye research 2026 Apr 28;269:111037
Experimental eye research 2026 Apr 28;269:111037
Brucea Javanica Oil Attenuates Osteosarcoma Progression by Reprogramming Tumor-associated Macrophages via Inhibiting PI3K/AKT Pathway.
Guo Y, Jiang Y, Li Z, Zhou J, Yao N
Applied biochemistry and biotechnology 2026 Apr 28;
Applied biochemistry and biotechnology 2026 Apr 28;
OLFM4 mediating ischemia/reperfusion-induced kidney injury by regulating renal tubular epithelial cells ferroptosis via GPX4.
Zhang Z, Wang Y, Mu Z, Zhao S, Zhang T, Zhang Z, Sun S, Bai M
Molecular biology reports 2026 Apr 25;53(1)
Molecular biology reports 2026 Apr 25;53(1)
Mesenchymal stem cells derived EXO-miR3671 delivery promoted angiogenesis and accelerated wound healing of diabetes.
Li J, Chen S, Wang H, Wang W, Liu Y
Stem cells (Dayton, Ohio) 2026 Apr 25;44(5)
Stem cells (Dayton, Ohio) 2026 Apr 25;44(5)
Engineered CAR-monocytes coordinate fibrosis clearance and cardiac regeneration following myocardial infarction.
Wu Z, Zou X, Chen C, Zhou M, Yue X, Guo D, Gao Y, Ma C, Han Q, Yang D, Zang D, Song R, Li Y, Pang S, Ren H, Zhang W, Zhang M, Zhang Y, Yang J, Jiang X, Zhang C
Cell stem cell 2026 Apr 24;
Cell stem cell 2026 Apr 24;
Discovery of FLC-8 as the First Covalent FLT3 Inhibitor Targeting Cys807 for FLT3 Mutant Acute Myeloid Leukemia.
Wang ZX, Jing XL, Liu Q, Xian T, Yang J, Zhang MY, Li QQ, Cai J, Yu YC, Sun SL, Li NG, Shi ZH
Journal of medicinal chemistry 2026 Apr 23;69(8):9635-9663
Journal of medicinal chemistry 2026 Apr 23;69(8):9635-9663
Enhanced Antiaging Effect of Fermented Ginseng through Biotransformation of Protopanaxadiol (PPD)-Type Ginsenosides to PPD.
Huang X, Li J, Naveed M, Wang Z, Du X, Li W, Wang Y, Yuan D, Wang C, Cheng Q, Chen Z, Wu S, Hou B, Li M, Li Y
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12244-12260
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12244-12260
KSR2 functions as a metabolic checkpoint for anti-PD-1 resistance by reprogramming glucose metabolism.
Ge Y, Zhou Q, Zhang Q, Hu Y, Wang R
Cancer immunology, immunotherapy : CII 2026 Apr 21;75(5)
Cancer immunology, immunotherapy : CII 2026 Apr 21;75(5)
Identification of Autophagy-related Genes of the Osteoarthritis Using Machine Learning Algorithm.
Zhang Z, Wang H, Cheng X, Zhang Z, Hou Z, Liu Z, Gao Y
Biochemical genetics 2026 Apr 21;
Biochemical genetics 2026 Apr 21;
Effect of Bacterial-Enzymatic Synergistic Liquid Fermented Rapeseed Meal on Growth Performance, Intestinal Health, and Muscle Development of Growing Pigs.
Liu J, Zhang T, Li Y, Zhang J, Zhao X, Li M, Cao G, Li B, Guo X, Yang Y
Animals : an open access journal from MDPI 2026 Apr 2;16(7)
Animals : an open access journal from MDPI 2026 Apr 2;16(7)
Cardiomyocytes FGFBP1 induction by STAT3 drives pathological cardiac remodeling.
Shen Y, Wang J, Ye L, Liu R, Wu H, Luo X, Zhou Q, Wang L, Liang G, Xu Z
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 19;:168269
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 19;:168269
Hepatocyte-Targeted Cyclic Peptide LYTACs for PCSK9 Degradation and LDL Cholesterol Metabolic Regulation.
Feng B, Shi Y, Xu J, Hu M, Liang S, Li Y, Gan W
ACS chemical biology 2026 Apr 17;21(4):801-811
ACS chemical biology 2026 Apr 17;21(4):801-811
Multi-Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean-Type and Chinese Indigenous Pigs.
Zheng S, Wu H, Liu M, Wu K, Huang S, Ahmed Z, Pius L, Zhu M, Xu D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 17;:e23959
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 17;:e23959
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Wang Y, Wang J, Chang Z
Applied biochemistry and biotechnology 2026 Apr 17;
Applied biochemistry and biotechnology 2026 Apr 17;
Liquiritin Enhances Chemosensitivity to Doxorubicin in Breast Cancer by Promoting Ubiquitination-Mediated Degradation of MCL1.
Wang D, Sun Y, Tang T, Shi X
Molecular carcinogenesis 2026 Apr 17;
Molecular carcinogenesis 2026 Apr 17;
KLOTHO Deficiency Drives Ovarian Aging by Inducing Granulosa Cell Senescence and Dysfunction.
Du W, Liu A, Li H, Ma X, Yang Y
Reproductive sciences (Thousand Oaks, Calif.) 2026 Apr 17;
Reproductive sciences (Thousand Oaks, Calif.) 2026 Apr 17;
Optineurin modulates mTORC2/AKT/STAT3 signaling to control MHC class II expression and adaptive immunity against HSV-1.
Kadam R, Patil C, Feferman L, Maienschein-Cline M, Chlipala G, Borole P, Bhattacharya I, Orameh C, Nyugen T, Tseng H, Shukla D
Cell reports 2026 Apr 16;45(4):117263
Cell reports 2026 Apr 16;45(4):117263
Piezo2 Mediates a Vicious Cycle of "Mechanical Homeostasis Imbalance-Inflammation" in Sensory Nerves and the Cartilage Endplate.
Xu H, Geng W, Du Z, Du Y, Wu D, Tong B, Liang H, Zhou X, Ou Z, Wei J, Wang K, Song Y, Hua W, Xu Y, Ke W, Wang B, Yang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e07299
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e07299
Dual-Shell Chitosan/Ferritin Nanocages Enhance the Stability, Intestinal Transport, and Antiviral Activity of EGCG against HBV.
Dong Y, Yin X, Shan X, Hu Y, Zhu C
Journal of agricultural and food chemistry 2026 Apr 15;74(14):11579-11591
Journal of agricultural and food chemistry 2026 Apr 15;74(14):11579-11591
Pyrazolylpyrimidinamines Decorated via Petasis Reaction as Small-Molecule Activators of the RNA-Degrading Ribonuclease IRE1α.
Avathan Veettil AK, Liu Y, Wagner L, Hastürk O, Huynh NST, Mancino G, Beerbaum M, Wu P
ACS bio & med chem Au 2026 Apr 15;6(2):118-129
ACS bio & med chem Au 2026 Apr 15;6(2):118-129
Persistent testicular glycogenolysis and active lipid metabolism during torpor in hibernating Siberian chipmunks.
Wang Z, Li LF, Yan YJ, Yuan MY, Zhao XY, Jiang LN, Yi XF
Journal of thermal biology 2026 Apr 15;139:104462
Journal of thermal biology 2026 Apr 15;139:104462
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
Ren D, Wu J, Zhu J, Xie C, Zhong C, Cao H, Han H, Zhu J
Phytotherapy research : PTR 2026 Apr 15;
Phytotherapy research : PTR 2026 Apr 15;
Dual RAF inhibition outperforms RAF-MEK combinations for suppressing ERK signaling in KRAS mutant cells.
Imoto H, Rauch N, Nagasato AI, Okada M, Kolch W, Rukhlenko OS, Kholodenko BN
NPJ systems biology and applications 2026 Apr 15;
NPJ systems biology and applications 2026 Apr 15;
Inhibition of iron overload and ferroptosis attenuates sepsis-induced myocardial injury in mice through STAT3/Lcn2 pathway.
Huang Y, Zhang L, Wang Y, He Y, Du R, Yun Q, Gao Q, Ye H
Journal of cardiothoracic surgery 2026 Apr 15;
Journal of cardiothoracic surgery 2026 Apr 15;
Generation of G9 genotype porcine rotavirus using reverse genetics system and its application for antiviral screen and vaccine development.
Han N, Tao R, Cheng X, Deng H, Wang J, Bian X, Zhou J, Zhu X, Sun M, Zhang X, Hu M, Guo R, Wang W, Ding S, Li B
Virologica Sinica 2026 Apr 15;
Virologica Sinica 2026 Apr 15;
ANP32E drives lung adenocarcinoma progression via GSK3β-mediated glycolytic reprogramming.
Wang Z, Li Q, Ye Z, Wu X, Fang C, Jiang W, Zhu M
Cell death & disease 2026 Apr 14;
Cell death & disease 2026 Apr 14;
Hantavirus L protein exhibits shutoff activity mediated by its N-terminal endonuclease domain.
Oishi K, Yoshikawa T, Taniguchi S, Kawahara M, Kurosu T, Shimojima M
Scientific reports 2026 Apr 14;
Scientific reports 2026 Apr 14;
Resveratrol improves follicular development in PCOS rats by inhibiting the inflammatory response and pyroptosis of granulosa cells†.
Wei H, Zhang Z, Zhang S, Wang J, Cui X, Zhang Z, Yu J, Lei X, Xiuhong Z, Huo P
Biology of reproduction 2026 Apr 13;114(4):1227-1240
Biology of reproduction 2026 Apr 13;114(4):1227-1240
High viscosity microenvironment induces chemoresistance of cancer cells through upregulating P-gp.
Zhou G, Wu C, Zhang W
International journal of pharmaceutics 2026 Apr 10;694:126753
International journal of pharmaceutics 2026 Apr 10;694:126753
Honghe Fujie lotion ameliorates pregnancy-associated vulvovaginal candidiasis in mice by inhibiting the activation of NLRP3 inflammasome.
Wang Y, Jiang Y, Shi S, Wang Y, Yang J, Kuang H, Feng X
Experimental animals 2026 Apr 10;
Experimental animals 2026 Apr 10;
ACT001 alleviates sepsis-induced acute lung injury by downregulating PANoptosis via the JAK2/STAT3 pathway.
Zhang N, Zhang H, Ping J, Shen N, Fang T, Fu Q
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 1;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 1;75(1)
Left bundle branch vs biventricular pacing: mechanistic insights from a canine model.
Huang H, Hu Y, Li H, Cheng S, Jiang Y, Weng S, He P, Yang J, Chen G, Liu X, Pei J, Chen L, Gu M, Ding L, Niu H, Jin H, Pan X, Vernooy K, Prinzen FW, Hua W
European heart journal 2026 Apr 1;47(13):1595-1605
European heart journal 2026 Apr 1;47(13):1595-1605
Manipulation therapy alleviates neuropathic pain via the SOCS1 m(6)A epigenetic loop.
Wu L, Wang X, Yang P, Wang X, Zheng Y, Tang Y, Zheng H, Ning P, Tang H
The Korean journal of pain 2026 Apr 1;39(2):191-206
The Korean journal of pain 2026 Apr 1;39(2):191-206
H3K27ac-induced IFITM3 promotes progression of TNBC and resistance to anti-PD-1/PD-L1 therapy via the TNF-α/NF-κB/PD-L1 axis.
Li G, Fu B, Wang X, Lin H, Chen X, Zhang J
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 1;1872(6):168238
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 1;1872(6):168238
METTL16 improves cigarette smoking-induced COPD emphysema through inhibiting autophagy by mediating pri-miR-511 m6A modification.
Cai X, Huang B, Gao F, Hu J, Yang F, Tang Y, Yu J, Tan X, Wang C, Qin H
International immunopharmacology 2026 Apr 1;174:116397
International immunopharmacology 2026 Apr 1;174:116397
Neuronal TLR4 upregulation activates the cGAS-STING pathway to induce ferroptosis in EAE mice.
Qin H, Yang L, Du J, Xu X, Chen Z, Li Q, Xu Y, Li M, Li Y, Jia Y
International immunopharmacology 2026 Apr 1;174:116364
International immunopharmacology 2026 Apr 1;174:116364
Bee sting acupuncture mitigates osteoarthritis in male mice via PPAR-γ activation: integrated network pharmacology, transcriptomics, and experimental validation.
Feng Z, Yang J, Zhu Y, Lei L, Zhang Y, Cheng L, Zhao H, Yao H, Shi P
International immunopharmacology 2026 Apr 1;174:116352
International immunopharmacology 2026 Apr 1;174:116352
β-alanine alleviates gout by inhibiting NLRP3 inflammasome activation.
Chen XY, Zhu PP, Ying Y, Feng MY, Xu YQ, Yu LB, Xue W, Yu Y, Li T, Zhou T
Journal of molecular cell biology 2026 Apr 1;
Journal of molecular cell biology 2026 Apr 1;
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.
Wang H, Gan Z, Wang Y, Hu D, Zhang L, Ye F, Duan P
Research (Washington, D.C.) 2025;8:0652
Research (Washington, D.C.) 2025;8:0652
Exploring plasticisers-osteoporosis links and mechanisms: a cohort and network toxicology study.
Yang X, Wang X, Bao S, Li Z, Xing S, Du Z
Frontiers in toxicology 2025;7:1617663
Frontiers in toxicology 2025;7:1617663
Tissue-specific effects of bacterial PncA overexpression on NAD(+) metabolism and aging in mice: implications for tissue-specific aging interventions.
Huo F, Zhao M, Liu Y, Lv S, Feng S, Guo L, Wang N, Zhang S, Liu Q, Mi T, Wang H, Zhu JK, Liu H
Frontiers in aging 2025;6:1546017
Frontiers in aging 2025;6:1546017
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
Gao L, Xiao H, Lu H, Ma J, Zhu H
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
Astaxanthin ameliorates allergic rhinitis via suppression of the HMGB1/TLR4 signaling pathway.
Lei X, Pan J, Deng K
Central-European journal of immunology 2025;50(3):276-289
Central-European journal of immunology 2025;50(3):276-289
Propofol Alleviates LPS-Induced Acute Lung Injury by Inhibiting Pulmonary Alveolar Epithelium Pyroptosis.
Zhang X, Tian X, Wang J, Zhuang Y
Biological & pharmaceutical bulletin 2025;48(11):1813-1821
Biological & pharmaceutical bulletin 2025;48(11):1813-1821
Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects.
Li X, Li Q, Huang Y, Zhou H, Yang Q, Kong L
Biological & pharmaceutical bulletin 2025;48(10):1485-1492
Biological & pharmaceutical bulletin 2025;48(10):1485-1492
Targeting p97/Valosin-Containing Protein Promotes Hepatic Stellate Cell Senescence and Mitigates Liver Fibrosis.
Yang Y, Zhang Y, Wang L, He G, Yang X, Qing J
DNA and cell biology 2025;44(3):132-143
DNA and cell biology 2025;44(3):132-143
Effects of borneol on apoptosis of hypoxia/reoxygenation H9c2 cells and myocardial ischemia-reperfusion injury rats.
Zhang H, Dong J, Zhang J, Chen H, Liu T, Gan R, Wen J, Li Y
Acta cirurgica brasileira 2025;40:e402225
Acta cirurgica brasileira 2025;40:e402225
Osteoclast-expanded supercharged NK cells perform superior antitumour effector functions.
Ko MW, Mei A, Senjor E, Nanut MP, Gao LW, Wong P, Chen PC, Cohn W, Whitelegge JP, Kos J, Kaur K, Malarkannan S, Jewett A
BMJ oncology 2025;4(1):e000676
BMJ oncology 2025;4(1):e000676
GPX4 predicts poor prognosis and regulates tumor proliferation and senescence in colorectal adenocarcinoma.
Zhang YU, Wang Q, Han Y, Piao J, Jin X
Oncology research 2025;33(8):1933-1945
Oncology research 2025;33(8):1933-1945
Developing a prognostic signature and characterizing the tumor microenvironment based on centrosome-related genes in lung adenocarcinoma.
Xu L, Xia Y, Qin Q, Wang G, Tao K, Wei W
Oncology research 2025;33(7):1649-1666
Oncology research 2025;33(7):1649-1666
CXCR1 and CXCR2 Antagonism with G31P Attenuates Chemotherapy-Induced Lung Inflammation and Augments the Gefitinib Therapeutic Response in Lung Cancer.
Khan MN, Tian K, Gordon JR, Li F, Ding SZ
Oncology research 2025;33(12):3837-3854
Oncology research 2025;33(12):3837-3854
CAMK2B Impacts the Proliferation, Invasion, and Migration of Glioma Cells via the Ras/Raf/MEK/ERK Signaling Pathway.
Zhang S, Li J, Jin Q, Zhu S, Yan H, Wang Y, Song Z, Liu L
Oncology research 2025;33(10):2961-2979
Oncology research 2025;33(10):2961-2979
HNRNPC as a pan-cancer biomarker and therapeutic target involved in tumor progression and immune regulation.
Zhang Y, Zhang Z, Dong J, Liu C
Oncology research 2025;33(1):83-102
Oncology research 2025;33(1):83-102
The Punicalagin Compound Mitigates Bronchial Epithelial Cell Senescence Induced by Cigarette Smoke Extract through the PAR2/mTOR Pathway.
Xu J, Li X, Zeng X, Bao H, Liu X
Current medicinal chemistry 2025;32(38):8701-8719
Current medicinal chemistry 2025;32(38):8701-8719
Bioengineered Anti-PD-L1 Functionalized Nanoplatform for Targeted Delivery and Tumor Immune Reprogramming Against Colorectal Cancer.
Liu M, Ma X, Zhou R, Yang X, Zhou Y, Ma B, Su C, Duan X
Biomaterials research 2025;29:0284
Biomaterials research 2025;29:0284
Targeting Reactive Oxygen Species and Inflammation in Sepsis-Induced Liver Injury with Naturally Derived Superoxide Dismutase-Mimicking Carbon Dots.
Zhong C, Song N, Huang P, Han L, Zhang J, Lu Z, Wang L
Biomaterials research 2025;29:0249
Biomaterials research 2025;29:0249
Targeting Smad3 Phosphorylation Attenuates Anastomotic Intimal Hyperplasia and Perigraft Fibrosis in Decellularized Tissue-Engineered Vascular Grafts.
Lu P, Wang T, Liao S, He Z, Cheng S, Wang T, Cheng Z, An Y, Zhou S, Wang M, Zhang Q, Shu C
Biomaterials research 2025;29:0241
Biomaterials research 2025;29:0241
Hsa_piR_016975 Is a Novel Target of Nanotherapy that Boosts Hepatoma Progression and Sorafenib Resistance by Abating Maspin/GPX4-Mediated Ferroptosis.
Feng W, Xu J, Chen B, Liu J, Hu Y, Cao X, Qi J, Ju L, Shao J, Dong P, Chen L, Wang F
Biomaterials research 2025;29:0225
Biomaterials research 2025;29:0225
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Biomaterials research 2025;29:0220
Biomaterials research 2025;29:0220
Integrated transcriptome and proteome analysis identifies keratins as key regulators of corneal scarring in a murine model.
Zhou T, Cai Y, Fang F, Cai X, Fu Y
Computational and structural biotechnology journal 2025;27:2264-2274
Computational and structural biotechnology journal 2025;27:2264-2274
MicroRNA-21 plays a role in exacerbating chronic obstructive pulmonary disease by regulating necroptosis and apoptosis in bronchial epithelial cells.
Zeng Z, Liu X, Xiang F, He X, Li J, Liu H, Xie L
Tobacco induced diseases 2025;23
Tobacco induced diseases 2025;23
Assessing the Role of Polyamine Metabolites in Blood and the DNA Methylation of Mycobacterium Tuberculosis in Patients with Multidrug-Resistant Tuberculosis.
Yan L, Niu X, Liang K, Guan F, Yu X, Ye Z, Huang M, Liang H, Zhong X, Zeng J
International journal of medical sciences 2025;22(8):1762-1772
International journal of medical sciences 2025;22(8):1762-1772
CD36 knockdown attenuates pressure overload-induced cardiac injury by preventing lipotoxicity and improving myocardial energy metabolism.
Geng J, Zhang X, Wang Y, Guo D, Liu P, Pu S, Yang X, Liang Q, Chang P, Li T, Hu L, Guo Y
International journal of medical sciences 2025;22(5):1223-1236
International journal of medical sciences 2025;22(5):1223-1236
Downregulation of lncRNA MNX1-AS1 promotes the ferroptosis and apoptosis of non-small cell lung cancer.
Chi X, Feng L, Wang L, Yu S, Wei M, Zhang Q, Liu X, Shao S
International journal of medical sciences 2025;22(5):1052-1063
International journal of medical sciences 2025;22(5):1052-1063
CLCN5 inhibits tumorigenesis and fatty acid accumulation in clear cell renal cell carcinoma by regulating Enoyl CoA hydratase and 3-Hydroxyacyl CoA dehydrogenase.
Yu T, Li W, Meng X, Yang W, Ruan H, Xiao W, Zhang X
International journal of medical sciences 2025;22(13):3354-3370
International journal of medical sciences 2025;22(13):3354-3370
Statins and Pacing-Induced Atrial Myopathy: Unraveling Their Role in Atrioventricular Block Patients with Permanent Pacemakers.
Lin YS, Ho WC, Lin MH, Kuo TY, Chung CM, Yen PC, Chen YL, Chen HC, Lee WC
International journal of medical sciences 2025;22(13):3342-3353
International journal of medical sciences 2025;22(13):3342-3353
Roxadustat: A catalyst for diabetic wound healing through re-epithelialization and angiogenesis.
Tang D, Lin Q, Xu K, Lu QP
CytoJournal 2025;22:90
CytoJournal 2025;22:90
Enhancing CAR-T Cell Metabolic Fitness and Memory Phenotype for Improved Efficacy against Hepatocellular Carcinoma.
You J, Yang X, Zhao J, Chen H, Tang Y, Ouyang D, Liu Y, Wang Y, Xie S, Chen Y, Liao J, Xiang T, Xia J, Yang C, Weng D
International journal of biological sciences 2025;21(9):4231-4251
International journal of biological sciences 2025;21(9):4231-4251
Unlocking the Puzzle of Mammalian Transfection: The Role of the RNA-sensing-Mediated Interferon Response in the Cellular Defense Against Foreign DNA Intrusion.
Li X, Zhou Y, Wei J, Sun W, Fan L, Yan J
International journal of biological sciences 2025;21(9):3886-3900
International journal of biological sciences 2025;21(9):3886-3900
Macrophage-derived S100A9 promotes diabetic cardiomyopathy by disturbing mitochondrial quality control via STAT3 activation.
Huo S, Wang M, Du M, Ren B, Yang T, Peng L, Jiang Y, Peng D, Men L, Shi W, Guo J, Zhang C, Lv J, Li S, Lin L
International journal of biological sciences 2025;21(7):3061-3080
International journal of biological sciences 2025;21(7):3061-3080
Cardiovascular Mettl3 Deficiency Causes Congenital Cardiac Defects and Postnatal Lethality in Mice.
Feng Q, Qi L, Huang J, Dong Z, Yu F, Zhang J, Zhan J, Zhang H, Wang W, Zhou Y, Yang Z, Zhou Y, Kong W, Fu Y
International journal of biological sciences 2025;21(6):2430-2445
International journal of biological sciences 2025;21(6):2430-2445
PPARG Activation of Fatty Acid Metabolism Drives Resistance to Anti-HER2 Therapies in HER2-Positive Breast Cancer.
Xiong M, Liu D, Wang X, Ren H, Chi W, Xiu B, Zhang Q, Zhang J, Zhang L, Wang Z, Chen M, Xue J, Chi Y, Wu J
International journal of biological sciences 2025;21(6):2396-2414
International journal of biological sciences 2025;21(6):2396-2414
BAP1 Represses Sequential Activation of IRAKs and NF-κB Signaling in Pancreatic Cancer.
Zhao Y, Liang X, Wei R, Guo F, Qin G, Yu H, Liu J, Xia W, Gou S, Wu H, Zhou Y
International journal of biological sciences 2025;21(5):1949-1965
International journal of biological sciences 2025;21(5):1949-1965
BRD7 Inhibited Immune Escape in Nasopharyngeal Carcinoma via Inhibiting PD-L1 Expression.
Guo Y, Lu J, Li X, Yan S, Zhou J, Tian Z, Liu Y, Li N, Zhou Q, Li X, Shi L, Jiang S, Li M, Zhou X, Huang D, Zeng Z, Fan S, Xiong W, Zhou M, Li G, Zhang W
International journal of biological sciences 2025;21(5):1914-1931
International journal of biological sciences 2025;21(5):1914-1931
Dysregulation of SRSF3/circSAMD4/CIRBP Axis Promotes Iodinated Contrast-induced Acute Kidney Injury.
Wu X, Wu T, Wang X, Zeng M, Tang C, Cai J, Chen A, Chen G, Liu Z, Liu Y, Duan S
International journal of biological sciences 2025;21(14):6156-6178
International journal of biological sciences 2025;21(14):6156-6178
Rabdosia rubescens Inhibits CYP7A1 Expression and Induces Autophagy to Reduce Alcohol-Induced Liver Damage in Mice.
Zou X, Chen W, Shao Y, Shi T, Ke Y
Canadian journal of gastroenterology & hepatology 2025;2025:9507266
Canadian journal of gastroenterology & hepatology 2025;2025:9507266
Single-Cell RNA-Seq Recognized Key Genes for Metastasis and Macrophage Infiltration in Colorectal Cancer.
Shi J, Zheng P, Ouyang L, Cui F
Human mutation 2025;2025:9488531
Human mutation 2025;2025:9488531
Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization.
Lin J, Ke L, Cheng S, Lu W, Hu Y, He X, Luo T, Liu Y, Xu C, Qi J
Mediators of inflammation 2025;2025:7977933
Mediators of inflammation 2025;2025:7977933
Hyperthermia Inhibits Growth and Stemness of Esophageal Squamous Cell Carcinoma Cells Through Promoting Degradation of GLI1.
Qin H, Li X, Duan S, Li S, Ren M
Stem cells international 2025;2025:7249890
Stem cells international 2025;2025:7249890
Identifying the Key Mitochondria-Related Genes in COPD by Integrating Machine Learning and Bioinformatics Analyses.
Qu J, Zhang M, Hu Y, Yang G, Zhang X, Zhang W, Qu Y
International journal of genomics 2025;2025:7060748
International journal of genomics 2025;2025:7060748
MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression.
Zhou F, Tian Y, Liao W, Ma Q, Bao H, Meng F, Jiang J
Anesthesiology research and practice 2025;2025:6624776
Anesthesiology research and practice 2025;2025:6624776
Decoding the Tumor Microenvironment of Myoepithelial Cells in Triple-Negative Breast Cancer Through Single-Cell and Transcriptomic Sequencing and Establishing a Prognostic Model Based on Key Myoepithelial Cell Genes.
Yu X, Tian Y, Zhang R, Yang Y
International journal of genomics 2025;2025:6454413
International journal of genomics 2025;2025:6454413
Systematic Analysis of an Immune-Related Gene Signature for Predicting Prognosis and Immune Characteristics in Primary Lower Grade Glioma.
Hou L, Tian L, Li J, Zhang Z, Han X, Zhou H, Xue X
BioMed research international 2025;2025:6180391
BioMed research international 2025;2025:6180391
Impaired Meningeal Lymphatic Drainage Aggravates LPS-Induced Neuroinflammation and Depression-Like Behaviors in Mice.
Shi C, Zhou Y, Zhang Q, Jin W, Dong H
Mediators of inflammation 2025;2025:4288671
Mediators of inflammation 2025;2025:4288671
Mdivi-1 Attenuates Sepsis-Associated Acute Lung Injury by Inhibiting M1 Alveolar Macrophage Polarization and Pyroptosis.
Zhang X, Fan H, Su L, Wang Y, Chen G
Mediators of inflammation 2025;2025:3675276
Mediators of inflammation 2025;2025:3675276
The Beneficial Effect of Lycium barbarum Polysaccharides on Insulin Resistance and Hepatic Glucose Production in Diabetes.
Wan F, Dang J, Huang S, Cai J, Lu Y, Wu J, Wang J, Ma L
Analytical cellular pathology (Amsterdam) 2025;2025:3176140
Analytical cellular pathology (Amsterdam) 2025;2025:3176140
Taohong Siwu Decoction Combined With the LncRNA H19/miR-675-5p Axis Repairs Limb Ischemia-Reperfusion Injury Through the Regulation of the Wnt3a/Ca(2+) Signaling Pathway.
Zhu F, Liu H, Cao Y, Dai B, Wu H, Zhu Y, Li W
Mediators of inflammation 2025;2025:3096848
Mediators of inflammation 2025;2025:3096848
Interleukin-4-Mediated NLRP3 Inflammasome Activation in Microglia Contributes to Allergic Rhinitis via Central Sensitization.
Lv H, Wang Y, Tan L, Xie Y, Liu P, Guan M, Cong J, Xu Y
Research (Washington, D.C.) 2025;2025:0897
Research (Washington, D.C.) 2025;2025:0897
1p-Enh-regulated CYP4B1 alleviates NNK-induced heart failure and lung cancer via the STAT3 pathway.
Dai L, Hu J, Yang Y, Qian B, Zuo X
PloS one 2025;20(9):e0331471
PloS one 2025;20(9):e0331471
TRIM6 affects the prognosis of acute myeloid leukemia through the PI3K/AKT signaling pathway and is associated with immune infiltration.
Zhang J, Zhou W, Liu Y, Hu C, Wang S, Xu J, Wei S
PloS one 2025;20(9):e0329560
PloS one 2025;20(9):e0329560
Downhill running regulates cardiac immune response through GCN2.
Bai X, Zhang W, Zhang Y, Xu X
PloS one 2025;20(8):e0329973
PloS one 2025;20(8):e0329973
Downregulation of NCOA4 expression indicates poor prognosis and promotes the progression of cholangiocarcinoma.
Shen W, Liu Y, Dai B, Qin C, Fu Y, Li X, Liu C
PloS one 2025;20(8):e0327722
PloS one 2025;20(8):e0327722
High SRD5A3 expression is correlated with promotion of proliferation and inhibition of apoptosis in B-cell non-Hodgkin lymphoma and suggests a poor prognosis.
Wei S, Sun J, Wen J, Yu J, Xuan Y, Huang J, Yang J, Zhang J
PloS one 2025;20(5):e0323965
PloS one 2025;20(5):e0323965
Exosomes from human umbilical cord mesenchymal stem cells promote the growth of human hair dermal papilla cells.
Chen YC, Tsai WC, Li ZX, Lin WJ, Lin HY, Hsieh YJ, Wang KH, Chen YY, Hwang TL, Lin TY
PloS one 2025;20(4):e0320154
PloS one 2025;20(4):e0320154
Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression.
He HF, Hou S, Ma XY, Huang SS, Yang B, Wang JK, Xu Y, Tan L, Li HY
PloS one 2025;20(4):e0319605
PloS one 2025;20(4):e0319605
Comparative analysis of translatomics and transcriptomics in the longissimus dorsi muscle of Luchuan and Duroc pigs.
Su S, Hu H, Liu K, Liu S, Luo Z, Yu J, Jiang T, Li X, Sun C, Yu L, Liang Y, Zhou L
PloS one 2025;20(3):e0319399
PloS one 2025;20(3):e0319399
Weifuchun alleviates MNNG-induced chronic atrophic gastritis by improving the gastric and intestinal microbiota homeostasis.
Chen Y, Feng P, Lou X, Wang H, Hong Y, Yang J, Wu S
PloS one 2025;20(11):e0333375
PloS one 2025;20(11):e0333375
Electroacupuncture alleviates pain-like behaviors through modulating DNMT3a/MOR signaling pathway in CCI rats.
Wang F, Zhou C, Xie C, Wang H, Li X, Zhao G
PloS one 2025;20(10):e0334695
PloS one 2025;20(10):e0334695
GsMTx-4 combined with exercise improves skeletal muscle structure and motor function in rats with spinal cord injury.
Zhang X, Liu X, Li Q, Li C, Li X, Qian J, Li J, Li X
PloS one 2025;20(1):e0317683
PloS one 2025;20(1):e0317683
LARP3 inhibits the apoptosis of hepatocellular carcinoma via the ROS/PI3K/c-Fos axis.
Zhu L, Meng Q, Qian W, Shao W, Lu Y, Jin S, Zhang A, Yan SG, Lu J
PloS one 2025;20(1):e0317454
PloS one 2025;20(1):e0317454
Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways.
Zhang B, Hou J, Liu J, He J, Gao Y, Li G, Ma T, Lv X, Dong L, Yang W
PloS one 2025;20(1):e0310852
PloS one 2025;20(1):e0310852
PSME2 exacerbates ulcerative colitis by disrupting intestinal barrier function and promoting autophagy-dependent inflammation.
Li M, Chen J, Xu S, Liu Z, Lu C, Ge S
Open life sciences 2025;20(1):20251196
Open life sciences 2025;20(1):20251196
BAP1 complexes with YY1 and RBBP7 and its downstream targets in ccRCC cells.
Wu Y, Li XY, Chen JD, Pan YF
Open life sciences 2025;20(1):20251140
Open life sciences 2025;20(1):20251140
CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis.
Yan X, Niu Y, Wang Y, Wei S, Han L, Guo Z, Zhao L, Gao F
Open medicine (Warsaw, Poland) 2025;20(1):20241100
Open medicine (Warsaw, Poland) 2025;20(1):20241100
Tetrahydropalmatine improves mitochondrial function in vascular smooth muscle cells of atherosclerosis in vitro by inhibiting Ras homolog gene family A/Rho-associated protein kinase-1 signaling pathway.
Ding K, Bao Q, He J, Wang J, Wang H
Open medicine (Warsaw, Poland) 2025;20(1):20241059
Open medicine (Warsaw, Poland) 2025;20(1):20241059
Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease.
Lin S, Ye Y, Lin S
Open life sciences 2025;20(1):20221043
Open life sciences 2025;20(1):20221043
GFPT2 promotes paclitaxel resistance in epithelial ovarian cancer cells via activating NF-κB signaling pathway.
Xu ZJ, Liu B, Li RN, Linghu H
Open life sciences 2025;20(1):20221039
Open life sciences 2025;20(1):20221039
Lymph Node Exosomes Delivery Attenuates Myocardial Ischemia-Reperfusion Injury via Regulating PTEN-PI3K/Akt Pathway Mediated Myocardiocyte Apoptosis.
Qiao S, Wu B, Chen L, Ma L, Wang Y, Xu B, Gu R
International journal of nanomedicine 2025;20:4967-4981
International journal of nanomedicine 2025;20:4967-4981
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
Wang W, Li Z, Lyu C, Wang T, Han C, Cui S, Wang J, Xu R
International journal of nanomedicine 2025;20:4035-4050
International journal of nanomedicine 2025;20:4035-4050
SYL3C Aptamer-DNA Tetrahedra Conjugates Enable Near-Infrared Fluorescent Imaging of Colorectal Cancer.
Huang Z, Li P, Li Y, Duan X, Li M, Jiang D, Li J
International journal of nanomedicine 2025;20:3595-3606
International journal of nanomedicine 2025;20:3595-3606
Honeysuckle-Derived Exosome-Like Nanovesicles Protect Against Acute Liver Failure by Modulating Gut Microbiota.
Li P, Tang Y, Chen Y, Fan W, Yao J, Yu K, Shan Y, Wang J, Ye XM, Zou H, Mou X
International journal of nanomedicine 2025;20:12975-12992
International journal of nanomedicine 2025;20:12975-12992
Construction of Baicalein-Loaded Chitosan Nanoparticles for Staphylococcus aureus-Induced Lung Infection Remission.
Wang J, Zhu R, Yang K, Lei Z, Zhang X, Sun Y, Zhang X
International journal of nanomedicine 2025;20:12009-12018
International journal of nanomedicine 2025;20:12009-12018
Bone Marrow Mesenchymal Stem Cells-Derived Exosomes Inhibit Apoptosis of Pulmonary Microvascular Endothelial Cells in COPD Mice Through miR-30b/Wnt5a Pathway.
Song Q, Zhou A, Cheng W, Zhao Y, Liu C, Zeng Y, Lin L, Zhou Z, Peng Y, Chen P
International journal of nanomedicine 2025;20:1191-1211
International journal of nanomedicine 2025;20:1191-1211
Ti(3)C(2)Tx MXene Potentiates PSAT1-Mediated Osteogenesis Through miR-665/GSK-3β/β-Catenin Axis to Counteract Inflammation-Induced Bone Loss.
Zhang J, Wang X, Xiao J, Hong H, Chen J, Wu C, Xu G, Cui Z
International journal of nanomedicine 2025;20:11151-11168
International journal of nanomedicine 2025;20:11151-11168
Activation of AMP-activated Protein Kinase by Metformin Inhibits Dedifferentiation of Platelet-derived Growth Factor-BB-induced Vascular Smooth Muscle Cells to Improve Arterial Remodeling in Cirrhotic Portal Hypertension.
Wu G, Fan Q, Chen M, Luo G, Wu Z, Zhao J, Lin J, Zhang C, Li H, Qi X, Huo H, Zheng L, Luo M
Cellular and molecular gastroenterology and hepatology 2025;19(6):101487
Cellular and molecular gastroenterology and hepatology 2025;19(6):101487
Ginkgolide B Alleviates LPS-Induced Inhibition of Osteogenic Differentiation in Human Periodontal Ligament Stem Cells by Suppressing the p-IκBα/NF-κB Pathway.
Du S, Yang D, Liu Q, Yang P, Wu Z, Zhang Y, Chen S, Zhang J
Drug design, development and therapy 2025;19:8309-8326
Drug design, development and therapy 2025;19:8309-8326
Salidroside Improves Periodontitis by Mitigating Inflammatory Reactions and Enhancing Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Li W, Liu Q, Chen S, Zhi M, Yang P, Zhang Y, Wu Z, Zhang J, Feng Q
Drug design, development and therapy 2025;19:8097-8114
Drug design, development and therapy 2025;19:8097-8114
Liu Wei Di Huang Decoction Alleviates Renal Fibrosis by Inhibiting Endothelial Mesenchymal Transitions via Upregulating Sirt1 Expression and Inhibiting the Wnt/β-Catenin Signaling Pathway.
Wang H, Chen SS, Zhang YX, Gao HB, Meng B, Wu WY, Tang Q
Drug design, development and therapy 2025;19:6587-6603
Drug design, development and therapy 2025;19:6587-6603
Astragaloside IV Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells via Activating PI3K/AKT/eNOS/NO Signaling Pathway: In vitro and in vivo Study.
Song Y, Hu J, Yang P, Zhang Y, Wu Z, Chen S, Zhang J
Drug design, development and therapy 2025;19:6073-6088
Drug design, development and therapy 2025;19:6073-6088
Lobetyolin Suppressed Osteoclastogenesis and Alleviated Bone Loss in Ovariectomy-Induced Osteoporosis via Hindering p50/p65 Nuclear Translocation and Downstream NFATc1/c-Fos Expression.
Xiu C, Luo H, Huang W, Fan S, Yuan C, Chen J, Xu C, Yao C, Hong D, Zhang L
Drug design, development and therapy 2025;19:4689-4715
Drug design, development and therapy 2025;19:4689-4715
Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression.
Zhang Y, Zhou M, Zhu L, Chen L, Zhang H, Huang Z, Zhou H
Drug design, development and therapy 2025;19:1895-1908
Drug design, development and therapy 2025;19:1895-1908
Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury.
Yan L, Zhou X, Li Q, Hong H, Wu C, Gao YJ, Cui Z, Xu G
Frontiers in cellular neuroscience 2025;19:1622825
Frontiers in cellular neuroscience 2025;19:1622825
Design, Synthesis and Evaluation of Novel Cyclopropanesulfonamide Derivatives for the Treatment of EGFR(C797S) Mutation in Non-Small Cell Lung Cancer.
Wang M, Xia Z, Nie W, Wang C, Nie H, Zhang S, Qiu J, Yang Y, Yao C, Xu L, An B
Drug design, development and therapy 2025;19:1403-1420
Drug design, development and therapy 2025;19:1403-1420
Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress.
Wang Y, Chen T, Shi Z, Dong L, Li M, Peng B, Li Q, Pan R, Xiao S, Yang Q, Jiang N, Liu X, Hu Q, Chen Y
Drug design, development and therapy 2025;19:1289-1303
Drug design, development and therapy 2025;19:1289-1303
Skullcapflavone II suppresses TGF-β-induced corneal epithelial mesenchymal transition in vitro.
Li MX, Zhang Z, Zhang Y, Zhao FR, Li YF, Dang YF, Yue YY, Li L
International journal of ophthalmology 2025;18(2):209-215
International journal of ophthalmology 2025;18(2):209-215
Qimai Feiluoping Decoction Inhibits EndMT to Alleviate Pulmonary Fibrosis by Reducing PI3K/AKT/mTOR Pathway-Mediated the Restoration of Autophagy.
Ma J, Ding L, Zang X, Yang Y, Zhang W, Li X, Zhao D, Zhang Z, Wang Z, Zhao L, Tong X
Journal of inflammation research 2025;18:8447-8475
Journal of inflammation research 2025;18:8447-8475
Hylotelephium mingjinianum Extract Attenuates Oxidative Stress and Inflammation in Experimental Periodontitis.
Yuan L, Kong C, Shi N, Chen J, Zhang T, Wang X
Journal of inflammation research 2025;18:8263-8276
Journal of inflammation research 2025;18:8263-8276
IGFBP1 is One of 10 Metabolic Factors Predicting Recurrence Free Survival in Gastric Cancer and Promotes Cancer Progression via ZFX-IGFBP1 Axis.
Liu H, Huang Y, Fu G, Lei B, Liu K
OncoTargets and therapy 2025;18:717-732
OncoTargets and therapy 2025;18:717-732
HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages.
Zhou J, Ding L, Chen J, Chen C, Jiang P, Mei Z, Jiang Q, Hua X
Journal of inflammation research 2025;18:6735-6748
Journal of inflammation research 2025;18:6735-6748
MiR-133a-5p Facilitates Cuproptosis in Hepatocellular Carcinoma Through Targeting of ATP7B.
Ren Q, Zhu X, Wang N, Yu K, Lv W, Wang L, Zang Y, Ma D, Zhou X, Yao J, Shen M, Yu L, Li T
Journal of inflammation research 2025;18:6607-6622
Journal of inflammation research 2025;18:6607-6622
Intermedin(1-53) Improves Atherosclerosis by Reducing Local Endothelial Damage via AMPK Signaling Pathway in Obese apoE-Deficient Mice.
Zhu HX, Ren JL, Cao WJ, Wang R, Chen LL, Gao Q, Zhou YB
Journal of inflammation research 2025;18:6583-6596
Journal of inflammation research 2025;18:6583-6596
Analysis and Validation of Mitophagy-Related Genes in Diabetic Foot Ulcers.
Fang S, Zhang H, Liu W, Li S, Chen Z, Min J, Dai C, An J, Zhang H, Liu D
Journal of inflammation research 2025;18:4367-4379
Journal of inflammation research 2025;18:4367-4379
Elucidating Molecule-Crosstalk of Neutrophil Extracellular Traps Between Cardiovascular Disease and Psoriasis: Insights Into Mendelian Randomization, Single-Cell RNA Analysis, Shared Targets and the Role of Resveratrol.
Jin X, Zhang Y, Qin G, Fang X, Zhang X, Sun J, Zhou M, Tong X, Xue Y, Yang H, Tian W
Journal of inflammation research 2025;18:3913-3935
Journal of inflammation research 2025;18:3913-3935
Uncovering the Interplay of Ferroptosis and Immune System in Coronary Artery Disease: Construction and Validation of a Diagnostic Model.
Zhang Z, Zhu X, Zhang T, Li C, Zhang D, Li W, Zhao L
International journal of general medicine 2025;18:3901-3917
International journal of general medicine 2025;18:3901-3917
Identification of Anoikis-Related Genes in Driving Immune-Inflammatory Responses in Ulcerative Colitis Based on Bioinformatics Analysis and Machine Learning.
Diao W, Huang X, Huang W, Jiang J, Li W, Liu H, Yan B, Shen L
Journal of inflammation research 2025;18:3227-3242
Journal of inflammation research 2025;18:3227-3242
Fu-Fang-Qi-Di-Hua-Yu-Tang Improves Diabetic Macrovascular Disease via PI3K/AKT Pathway Regulation.
Zhang S, Yan M, Liang P, Zhang Y, Liu J, Huang H, Li G, Wu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2247-2265
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2247-2265
TRIM6 Promotes Cell Cycle and Growth by Modulating p53 Signaling Pathway in Lung Adenocarcinoma.
Lu X, Wang H, Yu T
International journal of general medicine 2025;18:2107-2117
International journal of general medicine 2025;18:2107-2117
Integrating Extracellular Vesicles Proteomics and Clinical Parameters to Develop a High-Precision Predictive Model for Severe Asthma.
Qian Y, Wang F, Gao J, Jiang Z, Gao X, Chen Z
Journal of inflammation research 2025;18:17945-17960
Journal of inflammation research 2025;18:17945-17960
Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments.
Liu C, Liu W, Lu H, Fan Y, Wang A
Journal of inflammation research 2025;18:1543-1556
Journal of inflammation research 2025;18:1543-1556
Identifying Chemokine System-Related Phenotype to Predict Immune Feature in Pan-Cancer and Prognostic Signature for Lung Adenocarcinoma.
Zhao T, Wu X, Guo S, Nie J, Fang S, Wang L, Li X, Nie T, Yao K, Du X, Wang Y, Yuan Y, Ni J
Journal of inflammation research 2025;18:13213-13234
Journal of inflammation research 2025;18:13213-13234
Volatile Oil From Acorus Gramineus Rhizoma Synergizes with Crebanine to Alleviate Oxidative Stress and Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury by Suppressing GRP78-PERK/ATF6-CHOP and MAPK-NF-κB-TNF-α Signaling Pathways.
Zha L, Cui L, Mei J, Pu J, Hao J, Fan X, Wang H, Fang H, Ma Y
Journal of inflammation research 2025;18:12929-12948
Journal of inflammation research 2025;18:12929-12948
Quercetin Inhibits Gastric Cancer Progression via FAM198B/MAPK Pathway Modulation.
Deng H, Xiao Q, Xu X, Zhang L, Zhang Y
Pharmacogenomics and personalized medicine 2025;18:115-141
Pharmacogenomics and personalized medicine 2025;18:115-141
Artemether ameliorates type 1 diabetes mellitus by modulating glycolipid metabolism in skeletal muscle.
Dong Y, Fu Q, Zhang Y, Weng W, Han P, Cai Y, Sun H
American journal of translational research 2025;17(8):5871-5884
American journal of translational research 2025;17(8):5871-5884
Mesenchymal stem cells promote erlotinib resistance in non-small cell lung cancer through the HGF-AKT/ERK1/2-OPN pathway.
Yang Y, He J, Long F, Liu Y, Lin L, Wei H
American journal of translational research 2025;17(7):4952-4963
American journal of translational research 2025;17(7):4952-4963
Study of NOX4/ROS/NF-κB signaling pathway in anti-ischemia-reperfusion injury effect and mechanism of STQJD.
Luo C, Zhang L, Wang A, Wang Y, Cai J, Ni R, Yang R, He S, Gu L, Chen P
American journal of translational research 2025;17(7):4894-4911
American journal of translational research 2025;17(7):4894-4911
Electroacupuncture alleviates Parkinson's disease by inhibiting the NLRP3 inflammasome pathway.
Kang M, Cai J, Yi W, Zhang B, Ai L, Ning B, Dong J, Chen L, Fu W
American journal of translational research 2025;17(5):3619-3629
American journal of translational research 2025;17(5):3619-3629
MiR-124-3p inhibits proliferation, migration, and epithelial-mesenchymal transformation in gastric cancer by targeting ITGB1.
Li Q, Zhou L, Liang Q, Qin H, Chen Y, Wang T, Wei Q, Luo Y, Li G, Huang H
American journal of translational research 2025;17(4):2500-2512
American journal of translational research 2025;17(4):2500-2512
RBM10 suppresses malignant transformation in endometrial cancer via the Hippo-YAP signaling pathway.
Shi W, Wang M, Lin Q, Lv Z, Gao K, Wan X
American journal of translational research 2025;17(2):1480-1494
American journal of translational research 2025;17(2):1480-1494
Multi-target mechanism of 6-O-Caffeoylarbutin in hyperuricemia treatment through in vivo validation and network pharmacology.
Zhang Y, He F, Sun K, Yu X, Chen X, Zhou L, Liu S, Shen B
American journal of translational research 2025;17(10):8407-8420
American journal of translational research 2025;17(10):8407-8420
Aerobic exercise and gut flora: a key link to improved cognitive impairment in mice with Parkinson's disease.
Shan WP, Yan SL, Guo YY, Yang HK, Wang JC, Xiang J
Frontiers in aging neuroscience 2025;17:1630003
Frontiers in aging neuroscience 2025;17:1630003
Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy.
He YX, Zhang R, Xie C, Ji SF, Deng WJ, Teng JF
Frontiers in aging neuroscience 2025;17:1608631
Frontiers in aging neuroscience 2025;17:1608631
Experimental validation and identification of ferroptosis-associated biomarkers for diagnostic and therapeutic targeting in hearing loss.
Yuan C, Ma T, Liu M, Jiang L, Tang G, Hu Q, Zhang T
Frontiers in aging neuroscience 2025;17:1526519
Frontiers in aging neuroscience 2025;17:1526519
EIF4A3 Promotes Cell Proliferation via CDC5L Upregulation in Human Breast Cancer Cells.
Zhang M, Xie Y, Song S, Wang R, Chen H, Li Y, Liu J, Li J, Jiang Y, Liu P, Wang B
Journal of Cancer 2025;16(6):1958-1970
Journal of Cancer 2025;16(6):1958-1970
LncRNA C2orf27A Promotes Gastric Cancer by Sponging MiR-610 and Elevating NOX4 Expression.
Zhuang M, Guo X, Lin D, Lin N, Wang X, Chen F
Journal of Cancer 2025;16(5):1504-1518
Journal of Cancer 2025;16(5):1504-1518
Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways.
Yuan Q, Jiang H, Zhu M, Chu Y, Zhang Y, Bie J, Li L
Journal of Cancer 2025;16(3):765-783
Journal of Cancer 2025;16(3):765-783
ADAMTS7 Enhances Gastric Cancer Growth and Metastasis by Triggering the NF-κB Signaling Pathway.
Chen S, He J, Gao H, Gao X, Dai L, Chen J, Sha Z
Journal of Cancer 2025;16(3):1008-1019
Journal of Cancer 2025;16(3):1008-1019
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
Ji X, Yun Y, Zhu Z, Wu T, Ruan M, Fan Y, Zhang Q
Journal of Cancer 2025;16(15):4426-4439
Journal of Cancer 2025;16(15):4426-4439
Study on the mechanism of gracillin inhibiting the proliferation of lung cancer NCI-H1299 cells based on MAPK signaling pathway.
Xiao B, Zhang M, Liu H, Cui A, Tian Y, Tang F, Liao S, Li M, Huang H, Peng W, Yang J
Journal of Cancer 2025;16(10):3048-3064
Journal of Cancer 2025;16(10):3048-3064
Identification of IGF2BP3 and CENPA as key regulators of immunophenotypes in renal clear cell carcinoma.
Zhu T, He L, Li S, Zhao J
Frontiers in genetics 2025;16:1749780
Frontiers in genetics 2025;16:1749780
Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality.
Zhou X, Wang N, Wei J, Li G, Lue Z, Liu C, Bao Q, Feng Z, Zhang M, Huang H, Li Y, Wang J, Zhang X
Frontiers in pharmacology 2025;16:1732154
Frontiers in pharmacology 2025;16:1732154
Setmelanotide-mediated MC4R activation improves hypothalamic obesity via CaMKK2/AMPK pathways.
Peng J, Ou Y, Zhou M, Wang X, Zhang X, Long H, Wu G, Che M, Li K, Yang L, Zhang Z, Yung KKL, Qi S, Feng Z
Frontiers in pharmacology 2025;16:1730786
Frontiers in pharmacology 2025;16:1730786
Synergistic therapy for diabetic retinopathy via dual blockade of VEGF-A and TNF-α with a bispecific nanobody.
Wu C, Shen Y, Xu C, Bi C, Yan C, Niu J, Zheng W, Ma X
Frontiers in pharmacology 2025;16:1729606
Frontiers in pharmacology 2025;16:1729606
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Wang A, Zhou Y, Deng Z, Duan Y, Dai Z, Jiang D
Frontiers in immunology 2025;16:1719525
Frontiers in immunology 2025;16:1719525
WNT16 from decidual stromal cells orchestrates M2 macrophage polarization via β-catenin signaling and chromatin remodeling at the maternal-fetal interface.
Chang L, Guo J, Xue X, Yan Y, Li X, Zhao W, Sun X, Chen J, Du M
Frontiers in immunology 2025;16:1712898
Frontiers in immunology 2025;16:1712898
Cuproptosis-driven reprogramming of fibroblast communication by GK is associated with the immune microenvironment in diabetic foot ulcers.
Li T, Wang J, Gao L
Frontiers in immunology 2025;16:1687806
Frontiers in immunology 2025;16:1687806
HOXA5-mediated spatial remodeling of tumor-immune interfaces across cancers promotes AML pathogenesis.
Zhang C, Wen P, Zeng Y, Chen T, Guo Q, Liu C, Zhong F
Frontiers in immunology 2025;16:1677713
Frontiers in immunology 2025;16:1677713
The hypothalamic effects of PACAP on the hypothalamic-pituitary-gonadal axis in male mice.
Faludi P, Barabás K, Lengyel F, Udvarácz I, Pham D, Kisjós O, Nagy Z, Reglődi D, Kovács G
Frontiers in endocrinology 2025;16:1677085
Frontiers in endocrinology 2025;16:1677085
Thymoquinone and aerobic exercise mitigate HFpEF-induced cardiac injury via Apaf1/Cycs axis regulation.
Pei Z, Gao S, Yang J, Liu C, Pan Y
Frontiers in pharmacology 2025;16:1672570
Frontiers in pharmacology 2025;16:1672570
Cholestane-3β,5α,6β-triol induces cancer cell death by activating GSDME-mediated pyroptosis.
Chen J, He Y, Zhao M, Liu Z, Su Z, Li C, Yang C, Zhang J, Mao S, Han H, Cai Z, Zhang W
Frontiers in pharmacology 2025;16:1667156
Frontiers in pharmacology 2025;16:1667156
Exploring the mechanism of Heidihuang Pill in the treatment of osteoporosis based on network pharmacology, molecular docking, and experimental validation.
Tian Z, Cui K, Tian Y, Chen Y, Liu G, Zhang F, Hao Y, Li Y
Frontiers in endocrinology 2025;16:1664254
Frontiers in endocrinology 2025;16:1664254
Berberine protects against gefitinib-induced liver injury by inhibiting the HMGB1/TLR4/NF-κB pathway.
Zhang Q, Li N, Ma X, Qiu Y, Li C, Chen Y
Frontiers in pharmacology 2025;16:1645634
Frontiers in pharmacology 2025;16:1645634
Elucidating AML ribosome biogenesis reshaping prognostic assessment and immune microenvironment integrated single-cell and bulk RNA analysis.
Chen X, Feng A, Chen F, Zeng J, Chen M
Frontiers in immunology 2025;16:1644671
Frontiers in immunology 2025;16:1644671
Passive hydrotherapy preserves cartilage and muscle integrity in a murine osteoarthritis model: potential role of integrin αV/TGF-β mechanotransduction.
Di W, Songyang W, Ruibing F, Yong H, Hao H, Xiaofeng D, Yang R, Yunxiang D, Gang W
Frontiers in physiology 2025;16:1633618
Frontiers in physiology 2025;16:1633618
Fangchinoline attenuates hepatic fibrosis by regulating taurine metabolism and oxidative stress.
Yin H, Lian H, Wang Y, Chen L, Liu X, Liu Y
Frontiers in pharmacology 2025;16:1633519
Frontiers in pharmacology 2025;16:1633519
IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis.
Deng J, Gu J, Gong X, Tang H, Cai Y, Yang Y, Dong S, Zhao C
Frontiers in immunology 2025;16:1630253
Frontiers in immunology 2025;16:1630253
Large extracellular vesicles derived from LPS-preconditioned cardiomyocytes alleviate myocarditis via mediating macrophage polarization and modulating p38 MAPK pathway.
Jiang Y, You Y, Xie Y, Zhou S, Ma M, Han B
Frontiers in immunology 2025;16:1629676
Frontiers in immunology 2025;16:1629676
Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways.
Sun J, Zhang Y, Liu Z, Zhang H, Liu J, Xu Y, Na R, Zhang H, Yan J, Yu T
Frontiers in neurology 2025;16:1622602
Frontiers in neurology 2025;16:1622602
tRNA-derived small RNA 3' tRF-Ala CGC obstructs NK cytotoxicity via cleavage of membrane protein MICA in colorectal cancer.
Zhang J, Ou C, Li X, Fu L, Luo Q, Wang J, Zou Y
Frontiers in immunology 2025;16:1620550
Frontiers in immunology 2025;16:1620550
Identification of ferroptosis-genes associated with pediatric inflammatory bowel disease bioinformatics and machine learning approaches.
Xu Z, Yang M, Ou C, Mao L, Liu Z
Frontiers in immunology 2025;16:1619944
Frontiers in immunology 2025;16:1619944
Quercetin inhibits the cAMP/PKA/CREB/glycolysis axis to exert anti-acute lymphoblastic leukemia effects.
Ma Q, Liu W, Su Y, Guo J, Zhang M, Guo J, Liu M, Dong W, Li M, Wang B
Frontiers in pharmacology 2025;16:1614973
Frontiers in pharmacology 2025;16:1614973
Histone-related gene WDR77 promotes tumor progression through cell cycle regulation in skin cutaneous melanoma.
Zhang H, Tang K, Liu Y, Liu S
Frontiers in immunology 2025;16:1611112
Frontiers in immunology 2025;16:1611112
Mechanisms of skeletal muscle atrophy in type 2 diabetes mellitus.
Yang J, Wang Y, Xu Y, Jia X, Lu F
Frontiers in physiology 2025;16:1607873
Frontiers in physiology 2025;16:1607873
Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway.
Pang Y, Tian L, Liu Y, Guo Y, Zhao J, Wang Y, Wang M, Zhao W
Frontiers in endocrinology 2025;16:1606326
Frontiers in endocrinology 2025;16:1606326
Identification and validation of CKAP2 as a novel biomarker in the development and progression of rheumatoid arthritis.
Zheng Q, Lan Y, Chen J, Lin L
Frontiers in immunology 2025;16:1606201
Frontiers in immunology 2025;16:1606201
The pivotal regulatory role of the FEV-SLC7A11 axis in ferroptosis elucidates the anti-aging mechanism of β-sitosterol in a cross-species study.
Fang Z, Xie L, Wang J, Li J, Pan Y, Chen L, Cao S, Zhou Q, Li S, Zhang C, Li L
Frontiers in pharmacology 2025;16:1600489
Frontiers in pharmacology 2025;16:1600489
Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout.
Yuan Y, Gao Z, Chen J, Liu Y, Zhou J
Frontiers in genetics 2025;16:1598835
Frontiers in genetics 2025;16:1598835
Targeting revascularization via tryptophan-indole-NETs axis: the synergistic power of acupuncture and rt-PA thrombolysis in ischemic stroke.
Chang S, Zhao Y, Li C, Liu X, Fang Z, Peng Z, Gao M, Xia Y, Ni G
Frontiers in neurology 2025;16:1596158
Frontiers in neurology 2025;16:1596158
Comprehensive analysis of the functional and immunological significance of ETV4 in pan-cancer and its validation in digestive tumors.
Huang L, Li X, Huang S, Jiang Q, Jiang C, He W, Cai Y, Guo G
Frontiers in immunology 2025;16:1595850
Frontiers in immunology 2025;16:1595850
Baicalin enhances respiratory mucosal immunity by modulating antiviral protein expression and T-cell homeostasis during H9N2 infection.
Liu Z, Guo H, Zhi Y, Jiang X, Zhang Q
Frontiers in immunology 2025;16:1593691
Frontiers in immunology 2025;16:1593691
Collectin-11 promotes fibroblast proliferation and modulates their activation status and extracellular matrix synthesis.
Chen WB, Cao B, Li G, Wang G, Wu KY, Zhang T, Ma N, Zhou W, Li K
Frontiers in immunology 2025;16:1592921
Frontiers in immunology 2025;16:1592921
Shengyu decoction ameliorates knee osteoarthritis by inhibiting endoplasmic reticulum stress via Piezo1 channels.
Song X, Liu Y, Shen X, Zhang L, Kong H, Chen S, Sheng L, Sun R
Frontiers in pharmacology 2025;16:1592818
Frontiers in pharmacology 2025;16:1592818
CPLX1 is a novel prognostic biomarker in CRC correlating with immunotherapy resistance and ferroptosis.
Liu C, Liu Q, Lv Y, Chang T, Song S, Ding Y, Zhong J, Liu Y
Frontiers in immunology 2025;16:1589423
Frontiers in immunology 2025;16:1589423
Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways.
Wang SL, Liang S, Li SY, Fu JW, Wang ZY, Zhu DQ, Chen N
Frontiers in microbiology 2025;16:1586678
Frontiers in microbiology 2025;16:1586678
Correlation study of BDNF/TrkB/CREB, violence, and cognitive function in first-episode drug-naive schizophrenia patients.
Jiang T, Li Z, Yu T, Zhou X, Jiang T, Liang Y, Yu C, Zhu M, Wu W
Frontiers in psychiatry 2025;16:1586613
Frontiers in psychiatry 2025;16:1586613
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Chen H, Li G, Deng L, Xu N, Lee SM, Nie X, Bian JS
Frontiers in pharmacology 2025;16:1585181
Frontiers in pharmacology 2025;16:1585181
Gen-miR-5 derived from Gentianella acuta inhibits PFKP to prevent fibroblast activation and alleviate myocardial fibrosis.
Ge H, Du Z, Liu W, Wang L, Li J, Yang G, Li A
Frontiers in pharmacology 2025;16:1578877
Frontiers in pharmacology 2025;16:1578877
Targeting the BAG2/CHIP axis promotes gastric cancer apoptosis by blocking apoptosome assembly.
Liu Q, Chen Q, Wei H, Tang B, Tian B, Ma Z, Gu Q, Su X, Dong Y, Shi W, Luo C
Frontiers in immunology 2025;16:1578416
Frontiers in immunology 2025;16:1578416
METTL3-mediated m6A modification regulates D-galactose-induced skin fibroblast senescence through miR-208a-5p.
Huang G, Sun S, Liao M, Wang J, Yan Q, Li J, Meng Y, Wang Q, Guo Z, Tan J, Li J
Frontiers in immunology 2025;16:1577783
Frontiers in immunology 2025;16:1577783
Thrombospondin-1 mitigates osteoarthritis progression by inhibiting mechanical stress-induced chondrocyte ferroptosis via the integrin/YAP pathway.
Wang S, Zhou X, Zhang F, Zhai H, Zhang Y, Guo Y
Frontiers in immunology 2025;16:1577234
Frontiers in immunology 2025;16:1577234
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
Wu J, Xie W, Xie Y, Mazhar M, Duan J
Frontiers in pharmacology 2025;16:1573693
Frontiers in pharmacology 2025;16:1573693
(18)F-DOPA uptake illustration acts as an indicator for renal sympathetic activity.
Wu R, Shi S, Huang Y, Tian F, Hou J, Kong X, Sheng L, Zhang T, Tang L, Sun W
Frontiers in physiology 2025;16:1569699
Frontiers in physiology 2025;16:1569699
Osteopontin regulates right ventricular failure through integrin ανβ3/PERK/CHOP-dependent inflammatory and apoptotic pathways.
Yang X, Wang X, Li K, Deng Q, Hou Y, Xi G, Lu K, Liu Z, Bai Y, Wu J, Yu J, Zhang P
Frontiers in immunology 2025;16:1569210
Frontiers in immunology 2025;16:1569210
Thymoquinone alleviates the accumulation of ROS and pyroptosis and promotes perforator skin flap survival through SIRT1/NF-κB pathway.
Yang J, Zhang H, Ni L, He J
Frontiers in pharmacology 2025;16:1567762
Frontiers in pharmacology 2025;16:1567762
The protective role of cannabidiol in stress-induced liver injury: modulating oxidative stress and mitochondrial damage.
Huang C, Liang H, Liang X, Liu Y, Wang J, Jiang H, Kou X, Chen J, Huang L
Frontiers in pharmacology 2025;16:1567210
Frontiers in pharmacology 2025;16:1567210
CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.
Feng L, Zou X, Tang L, Yuan Y, He T, Su B, Tang Y, Wang J, Liu K, Li J
Frontiers in pharmacology 2025;16:1563869
Frontiers in pharmacology 2025;16:1563869
Ultrasound-assisted H(2)O(2) degradation enhances the bioactivity of Schizophyllan for wound healing and tissue regeneration.
He H, Liu Y, Li Q, Chen F, Zhou L
Frontiers in pharmacology 2025;16:1562839
Frontiers in pharmacology 2025;16:1562839
Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE(-/-) mice through the miR-34a/FGF-21 axis.
Tao N, He Z, Duan H, Wang L, Yi J, Shao J, Lv L, Duan J, Cao H, Dong X, Wang H
Frontiers in pharmacology 2025;16:1562321
Frontiers in pharmacology 2025;16:1562321
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
Frontiers in immunology 2025;16:1559966
TMED9: a potential therapeutic target and prognostic marker in glioma and its implications across pan-cancer contexts.
Mi B, Li C
Frontiers in immunology 2025;16:1558881
Frontiers in immunology 2025;16:1558881
High-dose radiation induces dendritic cells maturation by promoting immunogenic cell death in nasopharyngeal carcinoma.
Zeng X, Jin X, Leng J, Zhang S, Wang Y, Chen J, Zhang S, Teng L, Hu Z, Zhou S, Zeng Z, Long J
Frontiers in immunology 2025;16:1554018
Frontiers in immunology 2025;16:1554018
Synthesis, target analysis, and cerebroprotective effects of novel imide antioxidants via the Nrf2/HO-1 pathway in cerebral ischemia-reperfusion injury.
Huang L, Chen Y, Zhou H, Chen H, Wu X, Wu Z, Liu Z, Zheng Z
Frontiers in pharmacology 2025;16:1552717
Frontiers in pharmacology 2025;16:1552717
MFAP4 is a novel prognostic biomarker in glioma correlating with immunotherapy resistance and ferroptosis.
Lv Y, Gao Y, Di W, Li Z, Shi Y, Hou T, Chen Y, Tian J, Xu M, Su W, Zhang M, Zhong J
Frontiers in pharmacology 2025;16:1551863
Frontiers in pharmacology 2025;16:1551863
Cardiac protection of wogonin in mice with pulmonary fibrosis by regulating Sirt1/ γ-H2AX pathway.
Wang L, Lin F, Miao R, Zhao T, Liu Y, Yang L, Zhang M
Frontiers in pharmacology 2025;16:1551141
Frontiers in pharmacology 2025;16:1551141
TGFB1/CXCL5 axis regulation by LCN2 overexpression: a promising strategy to inhibit colorectal cancer metastasis and enhance prognosis.
Song X, Xu S, Song D, Wang J, Bai B, An Y, Yang B, Wang S, Zhao Q, Yu P
Frontiers in immunology 2025;16:1548635
Frontiers in immunology 2025;16:1548635
RNF5 inhibits HBV replication by mediating caspase-3-dependent degradation of core protein.
Xu J, Song H, Xu F, Gao Y, Jiang H, Tan G
Frontiers in microbiology 2025;16:1548061
Frontiers in microbiology 2025;16:1548061
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
Xi P, Zeng D, Chen M, Jiang L, Zhang Y, Qin D, Yao Z, He C
Frontiers in immunology 2025;16:1546242
Frontiers in immunology 2025;16:1546242
Dehydrodiisoeugenol targets the PLK1-p53 axis to inhibit breast cancer cell cycle.
Li L, Zheng Y, Yang Y, Shi S, Liu S, Huang K, Qiu L, Zhang R, Huang W, Leng Y
Frontiers in pharmacology 2025;16:1545498
Frontiers in pharmacology 2025;16:1545498
Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency.
Lee J, Mohammad N, Han K, Flagg-Dowie T, Magallon M, Brantly ML, Serban KA
Frontiers in immunology 2025;16:1543729
Frontiers in immunology 2025;16:1543729
CD8+ T cell activation in endometrial cancer: prognostic implications and potential for personalized therapy.
Guan H, Xiong Q, Xiong J, Liu Y, Zhang W
Frontiers in immunology 2025;16:1542669
Frontiers in immunology 2025;16:1542669
Comprehensive analysis of lncRNAs and mRNAs revealed potential participants in the process of avian reovirus infection.
Zhang S, Li J, Wang M, Jia R, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Huang J, Ou X, Sun D, Tian B, He Y, Wu Z, Cheng A
Frontiers in microbiology 2025;16:1539903
Frontiers in microbiology 2025;16:1539903
Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway.
Tian Y, Liu H, Bao X, Li Y
Frontiers in pharmacology 2025;16:1539411
Frontiers in pharmacology 2025;16:1539411
Deciphering the role of CNIH4 in pan-cancer landscapes and its significance in breast cancer progression.
Xu Y, Lai Z, Li C
Frontiers in genetics 2025;16:1536620
Frontiers in genetics 2025;16:1536620
Aberrant expression of PYGB as a potential therapeutic target and its associations with immune cell infiltration in lung cancer.
Sun K, Xu DC, Qin X, Xie FF
Frontiers in immunology 2025;16:1536248
Frontiers in immunology 2025;16:1536248
Isolation, phylogenetics, and characterization of a new PDCoV strain that affects cellular gene expression in human cells.
Yang X, Yin H, Liu M, Wang X, Song T, Song A, Xi Y, Zhang T, Sun Z, Li W, Niu S, Zainab F, Wang C, Zhang D, Wang H, Yang B
Frontiers in microbiology 2025;16:1534907
Frontiers in microbiology 2025;16:1534907
Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing.
Huang H, Ma J, Kang A, Guo T, Sun W, Xu Y, Ji L
Frontiers in immunology 2025;16:1534768
Frontiers in immunology 2025;16:1534768
Triptolide alleviates psoriasis through inhibiting the Wnt5a/β-Catenin signaling pathway.
Chen E, Wang L, Wang Q, Cai Y, Dou Y, Qu H, Zhu J, Zhao H, Zheng S, Zhao C, Chen B
Frontiers in pharmacology 2025;16:1534118
Frontiers in pharmacology 2025;16:1534118
Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway.
Jiang T, Liu Q, Liu H, Huang Z, Yang M, Huang P, Shen Y, Song Y, Xu W, Zhang X, Ni G
Frontiers in neurology 2025;16:1533092
Frontiers in neurology 2025;16:1533092
Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.
Wu Y, Chen L, Pi D, Cui J, Liang Y, Wu P, Ouyang M, Zuo Q
Frontiers in pharmacology 2025;16:1532579
Frontiers in pharmacology 2025;16:1532579
Development of a prognostic model for hepatocellular carcinoma based on microvascular invasion characteristic genes by spatial transcriptomics sequencing.
Mu X, Pan L, Wang X, Liu C, Li Y, Cai Y, He Z
Frontiers in immunology 2025;16:1529569
Frontiers in immunology 2025;16:1529569
Harmine derivative B-9-3 inhibits non-small cell lung cancer via the VEGFA/PI3K/AKT pathway.
Wu Y, Wang B, Mao X, Chen W, Akber Aisa H
Frontiers in pharmacology 2025;16:1526952
Frontiers in pharmacology 2025;16:1526952
Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats.
Li J, Li L, Yu Y, Qin R, Yu C, Chen C, Dong Y, Tan Y, Liu Y, Liu X
Frontiers in pharmacology 2025;16:1526828
Frontiers in pharmacology 2025;16:1526828
Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis.
Zhu W, Ma J, Zhang T, Zhu M, Duan Y, Yang X, Chen Y
Frontiers in pharmacology 2025;16:1522177
Frontiers in pharmacology 2025;16:1522177
Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.
Yang Y, Xiong G, Shi H, Peng Y, Liu J, Jiang Y, Lu M, Liu H, Liu Y
Frontiers in pharmacology 2025;16:1519497
Frontiers in pharmacology 2025;16:1519497
Discovery of novel and highly potent small molecule inhibitors targeting FLT3-ITD for the treatment of acute myeloid leukemia using structure-based virtual screening and biological evaluation.
Shi K, Hong Y, Liu H, Yang X, Wang F, Zhang Y
Frontiers in pharmacology 2025;16:1511257
Frontiers in pharmacology 2025;16:1511257
Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.
Li C, Wang L, Liu Z, Wang X, Sun L, Song X, Yu Z
Frontiers in pharmacology 2025;16:1510161
Frontiers in pharmacology 2025;16:1510161
Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia.
Li Z, Li Q, Wu S, Mei X, Qi X, Liu S, Qiao G, Shen H, Luo J, Zeng J, Huang F, Li R, Wang L
Frontiers in pharmacology 2025;16:1508215
Frontiers in pharmacology 2025;16:1508215
Alpha-estradiol and (R)-(-)-ibuprofen inhibit gastric cancer progression via GLI1 G-quadruplex.
Li Q, Pan P, Xian Q, Li J, Wang J, Cai J, Wang J, Jia Y, Sun H, Zhang L, Ma X
Frontiers in pharmacology 2025;16:1492694
Frontiers in pharmacology 2025;16:1492694
Genipin attenuates oxidative damage in periodontal tissues by alleviating mitochondrial dysfunction and abnormal glucose uptake through inhibition of UCP2.
Deng Y, Fu R, Shang Y, Hu M, Xin X, Hou Y, Yu W, Liu X
Frontiers in pharmacology 2025;16:1446574
Frontiers in pharmacology 2025;16:1446574
FAM49B suppresses ovarian cancer cell growth through regulating MAPK signaling.
Yue C, Zhou D, Zhou Y, Feng Q, Fang K, Meng S, Yu W, Du S, Shen D, Wang Y
American journal of cancer research 2025;15(9):4150-4164
American journal of cancer research 2025;15(9):4150-4164
RNF200 enhances radiotherapy sensitivity by modulating PD-L1 stability in tumor-associated macrophages of lung cancer.
Xu H, Cai F, Xu L, Jiang D, Wang G, Zhang X, Zhang Y
American journal of cancer research 2025;15(8):3449-3459
American journal of cancer research 2025;15(8):3449-3459
Splicing factor 3b subunit 4 (SF3b4) is mediated by EP300 and CREBBP to promote colorectal cancer (CRC) proliferation by enhancing autophagy.
Wu T, Xiao Z, Su B, Yan Z, Zhao Y, Huang C, Zhou L, Tian H, Zhang G
American journal of cancer research 2025;15(6):2826-2842
American journal of cancer research 2025;15(6):2826-2842
ESRP1 drives subtype-specific breast cancer progression through ER-regulated transcriptional programs and EMT-related splicing switch.
Wang X, Song S, Lin W, Huang J, Zhong W, Li D, Huo C, Wang Y, Chen D, Zhang Z, Sun Y
American journal of cancer research 2025;15(6):2807-2825
American journal of cancer research 2025;15(6):2807-2825
Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer.
Yuan H, Li X, Yu M, Cao Y, Wu L, Shi S, Yang Y, Yu K, Liang B
Theranostics 2025;15(17):8757-8778
Theranostics 2025;15(17):8757-8778
Engineered RAP-anchored copper-escorting liposomes for FDX1-targeted cuproptosis in glioblastoma therapy.
Liu MM, Zhao LX, Gong ZQ, He YJ, Jiang X, Luo W, Yu X, Wang ZY
Theranostics 2025;15(15):7802-7819
Theranostics 2025;15(15):7802-7819
Bioinspired nano-micron hydrogel microspheres for periodontitis therapy through synergistic multi-targeted remodeling of microenvironment.
Zhou S, Zhang Y, Zheng L, Liu C, Chen J, Liu Y, Ran S, He TC, Gu M, Wu S, Zhang F, Zhang H
Theranostics 2025;15(14):6857-6881
Theranostics 2025;15(14):6857-6881
Deciphering single-cell landscape unravels cell-type-specific functional roles of RNA m(6)A modification in atherosclerosis.
Ping X, Liang X, Xing W, Wang S, Gong F, Cheng Y, Duan S, Lv X, Li X, Zhang T, Chen C, Zhang Y, Yuan C, Liu S, Liu G, Sun B
Theranostics 2025;15(10):4785-4807
Theranostics 2025;15(10):4785-4807
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway.
Wang W, Wang Z, Li R, Huang W, Ling Q, Li X, Li Z, Cao M, Zhang Z, Sun Q, Liang Z, Zhang HA, Jiang X, Lin C, Chen Y, Zhao B, Zhao Y, Pan JA, Peng X
Theranostics 2025;15(10):4446-4464
Theranostics 2025;15(10):4446-4464
Asaraldehyde suppresses non-small cell lung cancer progression via ferroptosis induction and inhibition of PI3K-AKT signaling.
Yin H, Hu Z, You ZR, Xiao CX, Li XX, Liu ZF, Xu GQ
American journal of cancer research 2025;15(10):4276-4290
American journal of cancer research 2025;15(10):4276-4290
The ubiquitin ligase RCBTB2 regulates aggrephagy and inhibits prostate cancer progression by targeting GPAA1 for degradation.
Mo R, Chi N, Du J, Li X, Guo W, Li H, Wang J, Cai C, Li S, Liu C
American journal of cancer research 2025;15(10):4245-4263
American journal of cancer research 2025;15(10):4245-4263
Identification of sinensetin as a selective inhibitor for mitogen-activated protein kinase kinase 6 and an anticancer agent for non-small cell lung cancer.
Xie X, Shin YR, Kim TS, Seong YS, Yi YW, Kim DJ
American journal of cancer research 2025;15(1):113-126
American journal of cancer research 2025;15(1):113-126
Clinical value and molecular role of PRDXs family in prostate cancer.
Yao Y, Zheng Q, Qian C, Gu P, Zhang M, Zhang Z
Frontiers in oncology 2025;15:1713670
Frontiers in oncology 2025;15:1713670
Mechanistic insights into GPAA1-mediated cold tumor phenotype and immune evasion in colorectal cancer: integrative multi-omics analysis and experimental validation.
Zhu J, Zhu T, Cai Y, Fan H
Frontiers in oncology 2025;15:1701368
Frontiers in oncology 2025;15:1701368
Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role.
Ao W, Liu TH, Yin DT, Zhao WX
Frontiers in oncology 2025;15:1700439
Frontiers in oncology 2025;15:1700439
Metabolic reprogramming-driven stratification and therapeutic targeting in lung adenocarcinoma: implications for prognosis and personalized treatment.
Jia J, Feng S, Wang R, Zhao X, Cui Y
Frontiers in oncology 2025;15:1696117
Frontiers in oncology 2025;15:1696117
PPP2CA knockdown upregulates the expression levels of ferroptosis-related genes TFRC and ACSL4 in colorectal cancer cells by promoting mTOR phosphorylation.
Cheng J, Liu Z, Liu H, Fang C, Li J
Frontiers in oncology 2025;15:1694932
Frontiers in oncology 2025;15:1694932
Ivermectin attenuates Schistosoma japonicum-induced liver fibrosis and is associated with downregulation of YAP signaling.
Xuan M, Zhang P, Guo J, Guan F, Lu S, Liu W
Frontiers in cellular and infection microbiology 2025;15:1678067
Frontiers in cellular and infection microbiology 2025;15:1678067
Ginsenoside Rh2 repressed the progression of prostate cancer through the mitochondrial damage induced by mitophagy and ferroptosis.
He Z, Shi J, Zhu B, Tian Z, Zhang Z, Zhang C
Frontiers in oncology 2025;15:1633891
Frontiers in oncology 2025;15:1633891
CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway.
Hou L, Hao Z, Zhang G, Li J, Wang Y, Xue X, Zhou H
Frontiers in oncology 2025;15:1625120
Frontiers in oncology 2025;15:1625120
Saxifraga stolonifera inhibits porcine epidemic diarrhea virus infection by disrupting nucleocapsid protein-p53 interaction.
Lu H, Liu H, Guo N, Zhou Y, Lu H, He Z, Dong H
Frontiers in cellular and infection microbiology 2025;15:1615300
Frontiers in cellular and infection microbiology 2025;15:1615300
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
Guan X, Han L
Frontiers in oncology 2025;15:1590095
Frontiers in oncology 2025;15:1590095
SIRT7 deletion inhibits Glaesserella parasuis-mediated inflammatory responses in porcine alveolar macrophages.
Zheng H, Wang B, Dong X, Wu J, Shi L, Zhang J, Chen H, Zhou A
Frontiers in cellular and infection microbiology 2025;15:1589199
Frontiers in cellular and infection microbiology 2025;15:1589199
p53 enhances elesclomol-Cu-induced cuproptosis in hepatocellular carcinoma via FDXR-mediated FDX1 upregulation.
Liu X, Qu H, Li J, Sun X, Wang Z, Wang D, Bai X, Li X
Frontiers in oncology 2025;15:1584811
Frontiers in oncology 2025;15:1584811
Unraveling the role of coagulation-related genes in esophageal squamous cell carcinoma: development of a prognostic model and exploration of potential clinical significance.
Deng L, Fang C, Zhang W, Zhu Z, Gu Y, Gu P, Tan X, Yuan J, Feng Y, Ma H
Frontiers in oncology 2025;15:1573279
Frontiers in oncology 2025;15:1573279
TFRC promotes the proliferation, migration, and invasion of osteosarcoma cells by increasing the intracellular iron content and RRM2 expression.
Ren G, Zhou J, Su Y, Yang Q, Li J
Frontiers in oncology 2025;15:1567216
Frontiers in oncology 2025;15:1567216
Synergistic effects of 5-fluorouracil in combination with salinomycin promoted ferroptosis via inhibiting SLC7A11/GPX4 in colorectal cancer.
Wang C, Wang J, Xing F, Liu N, Wang X
Frontiers in oncology 2025;15:1558290
Frontiers in oncology 2025;15:1558290
Correlation of heat shock protein 1 expression with progression and prognosis of non-small cell lung cancer.
Wang R, Guo R, Huang T, Lu Y, Zhang W, Wang Y, Ni Q, Song J, Li X
Frontiers in oncology 2025;15:1553248
Frontiers in oncology 2025;15:1553248
Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.
Cui Y, Liu Z, Zhang L, Men K, Wang M, Hu Y, Zhang Z, Liu X, Wang X
Frontiers in oncology 2025;15:1532772
Frontiers in oncology 2025;15:1532772
Endosialin promotes vascular maturation by inhibiting Cyr61 expression in melanoma metastasis.
Lu T, Song H, Zhao Z, He X, Xu C, Liu S, Qin W, Yang B, Yang L
Frontiers in oncology 2025;15:1528288
Frontiers in oncology 2025;15:1528288
Fracture-Induced Immunological Cascades Trigger Rapid Systemic Bone Loss via Osteocyte-Regulated Osteoclastogenesis.
Sun L, Kuang S, Li Y, Wang G, Sun J, Zhou F, Zhang C
ImmunoTargets and therapy 2025;14:849-875
ImmunoTargets and therapy 2025;14:849-875
Lysyl Oxidase-Like 1 (LOXL1) Up-Regulation in Chondrocytes Promotes M1 Macrophage Activation in Osteoarthritis via NF-κB and STAT3 Signaling.
Jiang Y, Wang S, Zhu W, Liu X, Yang Y, Huo L, Ye J, Ma Y, Zhou Y, Yang Z, Mao J, Wang X
ImmunoTargets and therapy 2025;14:259-278
ImmunoTargets and therapy 2025;14:259-278
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Ren X, Wang Z, Wang J, Li X, Wei H, Liu C, Liu S, Zhu Y, Feng C, Yin Y, Tian Y, Wu M, Zeng X
ImmunoTargets and therapy 2025;14:151-173
ImmunoTargets and therapy 2025;14:151-173
2'-Hydroxyflavanone inhibits bladder cancer cell proliferation and angiogenesis via regulating miR-99a-5p/mTOR signaling.
Qi T, He F, Wu S, Wang Q, Huang J, Dai R, Jiang Z, Zhou M, He D, Wu K
American journal of clinical and experimental urology 2025;13(1):20-32
American journal of clinical and experimental urology 2025;13(1):20-32
IGF1R promotes radiation-induced HSCs activation by regulating DNA-PKcs-mediated DNA damage repair.
Lin J, Zhao G, Feng J, Sun C, Liu C, Li J, Shen Y, Cheng Y
Frontiers in cell and developmental biology 2025;13:1678654
Frontiers in cell and developmental biology 2025;13:1678654
Spatial transcriptomics reveals Inhba/Smad2/E2f4 axis in Lrp2(high) thecal cell proliferation in androgen-induced PCOS mice.
Luo M, Tian X, Li L, Zhang G, Liu W, Mei L, Li H, You X, Zhang D, Zhou M, Xiao C, Ye J, Yang X
Frontiers in cell and developmental biology 2025;13:1633254
Frontiers in cell and developmental biology 2025;13:1633254
Induced neural stem cells ameliorate blood-brain barrier injury by modulating the calcium signaling pathway of astrocyte in cerebral ischemia-reperfusion rats.
Liang X, Cao C, Liu N, Chen D, Liu T, Ma H, Liu J, Wu T, Niu J
Frontiers in cell and developmental biology 2025;13:1611226
Frontiers in cell and developmental biology 2025;13:1611226
HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.
Yu XZ, Zhu WL, Qian HC, Sun CJ
Frontiers in chemistry 2025;13:1607067
Frontiers in chemistry 2025;13:1607067
Identification and verification of international neuroblastoma staging system (INSS) stage-related genes as potential biomarkers for neuroblastoma prognostic models.
Qi C, Zhao Z, Qi Y, Zhou Y, Yue F, Niu H, Duan G, Zhong Z, Wang L
Frontiers in cell and developmental biology 2025;13:1502380
Frontiers in cell and developmental biology 2025;13:1502380
Aligned nanofibers in biomimetic periosteal extracellular matrix/poly(ε-caprolactone) membranes enhance bone regeneration via the ITGB1/PI3K/AKT pathway.
Wen Z, Li S, Qiu H, Liu X, You Z, Yan Y, Che Y, Zhou M
Regenerative biomaterials 2025;12:rbaf099
Regenerative biomaterials 2025;12:rbaf099
Prognostic Signature of NETs-Related Genes in Hepatocellular Carcinoma Based on Bulk and Single-Cell Transcriptomics.
Lu N, Gu Z, Yuan X, Jin R, Li J
Journal of hepatocellular carcinoma 2025;12:2351-2367
Journal of hepatocellular carcinoma 2025;12:2351-2367
Low Indoleamine 2,3-Dioxygenase 1 Expression Enhances Dendritic Cells Response to Tumor Cells Against Hepatocellular Carcinoma.
Mo C, Hong M, Li Y, Huang D, Ji Q, Liu Y
Journal of hepatocellular carcinoma 2025;12:2149-2167
Journal of hepatocellular carcinoma 2025;12:2149-2167
Garlic oil-loaded nanodisks for the amelioration of acute lung injury via modulation of the NF-κB and Keap1-Nrf2 axis.
Hou R, Jiang B, Wang K, Yang X, Zhang W
Frontiers in molecular biosciences 2025;12:1686436
Frontiers in molecular biosciences 2025;12:1686436
Oral supplementation with Lactobacillus fermentum MC018 improves intestinal health, immune response, and growth performance of Zi geese infected with Escherichia coli XH197291.
Li Y, Liu M, Li Z, Dong M, He L, Li P, Chen R, Liang Y, Yang L, Li F, Zhou Y, Zhu Z, Liu Y
Frontiers in veterinary science 2025;12:1666985
Frontiers in veterinary science 2025;12:1666985
Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.
Yu J, Mei W, Zhu J, Wang Z, Liu X, Zhou R, Liu X
Frontiers in nutrition 2025;12:1661040
Frontiers in nutrition 2025;12:1661040
Single-Cell RNA Sequencing Integrated with Bulk-RNA Sequencing Analysis Reveals Prognostic Signatures Based on PANoptosis in Hepatocellular Carcinoma.
Wang J, Yin X, Li Z, Liang P, Wang Y, Li X, Qiao W, Xiong C, Yu M, Ding X, Wang X
Journal of hepatocellular carcinoma 2025;12:1661-1676
Journal of hepatocellular carcinoma 2025;12:1661-1676
Echinocystic acid in Momordica charantia L. exosome-like nanovesicles attenuates dengue virus-induced vascular leakage associated inflammatory mediators through macrophage metabolic reprogramming and HIF-1α/p300-CBP interaction.
Liu H, He J, Xu L, Chen Y, Wang X, Pang X, Yang H, Liang L, Chen S, Li S
Frontiers in medicine 2025;12:1653689
Frontiers in medicine 2025;12:1653689
A mitochondrial ferroptosis-related gene signature predicts prognosis and immune landscape in colon cancer.
Wang H
Frontiers in medicine 2025;12:1614012
Frontiers in medicine 2025;12:1614012
Bone marrow mesenchymal stem cell-derived exosomal microRNA-335 alleviates vascular calcification by targeting SP1.
Li Y, Chen C, Kong J, Huang J, Liu L, Liu C, Dai B, Huang M
Frontiers in cardiovascular medicine 2025;12:1572045
Frontiers in cardiovascular medicine 2025;12:1572045
N6-methyladenosine RNA landscape in the aged mouse hearts.
Jing X, Li Y, Liao Z, Wu JY, Xu ZY, Yang ZP, Mo HL, Xu S, Liu X, Wu Z, Tao J, Xiong XD
Frontiers in cardiovascular medicine 2025;12:1563364
Frontiers in cardiovascular medicine 2025;12:1563364
Luteolin attenuates LPS-induced damage in IPEC-J2 cells by enhancing mitophagy via AMPK signaling pathway activation.
Yuan J, Zhang K, Yang L, Cheng X, Chen J, Guo X, Cao H, Zhang C, Xing C, Hu G, Zhuang Y
Frontiers in nutrition 2025;12:1552890
Frontiers in nutrition 2025;12:1552890
Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways.
Ma Q, Chen K, Xiao H
Frontiers in molecular biosciences 2025;12:1548810
Frontiers in molecular biosciences 2025;12:1548810
Chloride channel-3 regulates sodium-iodide symporter expression and localization in the thyroids of mice on a high-iodide diet.
Yu M, Deng Z, Wang K, Zhang X
Frontiers in nutrition 2025;12:1537221
Frontiers in nutrition 2025;12:1537221
Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation.
Xu L, Zeng K, Duan Z, Liu J, Zeng Y, Zhang M, Yang Y, Guo Q, Jin Y, Liu W, Guo L
Frontiers in nutrition 2025;12:1518525
Frontiers in nutrition 2025;12:1518525
MgSO(4) alleviates hippocampal neuroinflammation and BBB damage to resist CMS-induced depression.
Wang Q, Hu Y, Li F, Hu L, Zhang Y, Qiao Y, Tang C, Wang R
Frontiers in nutrition 2025;12:1470505
Frontiers in nutrition 2025;12:1470505
Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.
Du M, Yao C, Lv Q, Gong A, Zhu Y, Li J, Zhong J
Frontiers in medicine 2025;10:1530092
Frontiers in medicine 2025;10:1530092
NanoBiT-based Analysis of Canine SOD1 Protein Dynamics: Understanding the Role of CCS and Ebselen Derivatives as Potential Therapeutics for Canine Degenerative Myelopathy.
Hirose S, Kobatake Y, Tada N, Kandeel M, Itoh A, Oh-Hashi K
Cell biochemistry and biophysics 2025 Sep;83(3):3945-3958
Cell biochemistry and biophysics 2025 Sep;83(3):3945-3958
GSK3A promotes human adenovirus replication and phosphorylates viral L4-22K protein.
Lin Y, Zhu Y, Jing L, Chen Y, Xiao X, Lei X, Xie Z
Life science alliance 2025 Sep;8(9)
Life science alliance 2025 Sep;8(9)
Anti-asthmatic effects of andrographolide on OVA-stimulated mice via Th17 cell differentiation-mediated glycolytic pathway.
Yu Q, Ding X, Xu C, Zhu L, Lou Y
Archives of biochemistry and biophysics 2025 Sep;771:110514
Archives of biochemistry and biophysics 2025 Sep;771:110514
miR-142 regulates the function of microvascular endothelial cells through MAT2B.
Liu CY, Chen DC, Zhang ZH, Li TR, Ji LL
Archives of biochemistry and biophysics 2025 Sep;771:110501
Archives of biochemistry and biophysics 2025 Sep;771:110501
Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NETformation.
Lu K, Xia Y, Cheng P, Li Y, He L, Tao L, Wei Z, Lu Y
Journal of advanced research 2025 Sep;75:739-753
Journal of advanced research 2025 Sep;75:739-753
Ozone water enema activates SIRT1-Nrf2/HO-1 pathway to ameliorate gut dysbiosis in mice receiving COVID-19 patient-derived faecal microbiota.
Su Z, Lin J, Zeng X, Li X, Hou Q, Wang Q, Liu C, Qin J, Li Y, Zhang J, Wang X, Qian S, Liao L
Journal of medical microbiology 2025 Sep;74(9)
Journal of medical microbiology 2025 Sep;74(9)
Protease Inhibitor VR23 Alleviates Severe Acute Pancreatitis with High Trypsin Synthesis in Mice.
Yang J, Yang X, Li X, Liang J, Zhang L, Xia L, Wan J
Digestive diseases and sciences 2025 Sep;70(9):3066-3076
Digestive diseases and sciences 2025 Sep;70(9):3066-3076
Berberine dissociates mitochondrial complex I by SIRT3-dependent deacetylation of NDUFS1 to improve hepatocellular glucose and lipid metabolism.
Wang X, Li H, Li J, Lei L, Xu J, Sun H, Li J, Jiang J, Li H, Tang M, Dong B, Gong Y, Jiang J, Peng Z
Science China. Life sciences 2025 Sep;68(9):2676-2696
Science China. Life sciences 2025 Sep;68(9):2676-2696
HBV Precore G1896A Mutation Promotes Malignancy of Hepatocellular Carcinoma by Activating Endoplasmic Reticulum Stress to Enhance Aerobic Glycolysis.
Zhao B, Qiao H, Gao Z, Zhao Y, Wang W, Cui Y, Li F, Wang Y, Guo Z, Chuai X, Chiu S
MedComm 2025 Sep;6(9):e70365
MedComm 2025 Sep;6(9):e70365
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways.
Guo H, Cao H, Lu Q, Gu Z, Feng G
International journal of molecular medicine 2025 Sep;56(3)
International journal of molecular medicine 2025 Sep;56(3)
Daughter Cells Budding From PGCCs and Their Clinicopathological Significances in Oral Squamous Cell Carcinoma.
Zhuo S, Jing C, Liu X, Yue J, Zhang W, Zhang S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Sep;54(8):687-693
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Sep;54(8):687-693
EIF3B‑METTL3 complex promotes cell proliferation, invasion and EGFR/AKT signaling in cervical cancer.
Zhang C, Fan X, Yang J, Zhu P
Oncology reports 2025 Sep;54(3)
Oncology reports 2025 Sep;54(3)
Oxidative stress activates YAP/TEAD1/NCOA4 axis to promote ferroptosis of endplate chondrocytes and aggravate intervertebral disc degeneration.
Wang H, Liu X, Jing X, Zhang B, Liu X, Liu X, Jia F, Su C, Wang W, Cui X
Journal of orthopaedic translation 2025 Sep;54:8-25
Journal of orthopaedic translation 2025 Sep;54:8-25
Overexpression of JAML in colorectal cancer cells predicts higher radiosensitivity by inactivating ATR pathway.
Zhang M, Shi W, Liu Y, Wang Y, Dong Y, Yang C, Zheng Y, Liu N, Zheng Y, Sun M
Clinical and translational radiation oncology 2025 Sep;54:101016
Clinical and translational radiation oncology 2025 Sep;54:101016
Changes of N6-methyladenosine and ferroptosis in cadmium-induced reproductive toxicity of male mice fed a high fat and high sugar diet.
Liu D, Zhao Y, Dai J, Li R, Yuan J, Shen K, He Z, Gu S
Toxicology 2025 Sep;516:154172
Toxicology 2025 Sep;516:154172
Telaprevir attenuates caspase-11-dependent pyroptosis in mouse heart following ischemia/reperfusion via inhibition of MALT1/TRAF6 pathway.
Li MR, Yao BF, Tang C, Luo XJ, Peng J
Toxicology and applied pharmacology 2025 Sep;502:117448
Toxicology and applied pharmacology 2025 Sep;502:117448
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels.
Chen J, Liao D, Wu C, Liu L, Luo J, Li G, Cao L
Journal of ginseng research 2025 Sep;49(5):594-603
Journal of ginseng research 2025 Sep;49(5):594-603
Study of the Reciprocal Interaction Between Tumor Cells and Macrophages Based on the Biomimic Microfluidic Device.
Jin S, Wu Q, Chang S, Zeng S, Yin J, Ma H
Electrophoresis 2025 Sep;46(18):1388-1396
Electrophoresis 2025 Sep;46(18):1388-1396
ZMYND8 promotes the Warburg effect and tumorigenesis through c-Myc activation in pancreatic cancer.
Liu H, Zhao Z, Wu C, Chen J, He Z, Jiang K
Oncogene 2025 Sep;44(34):3083-3095
Oncogene 2025 Sep;44(34):3083-3095
RBM5 recruiting MGC32805 in a sandwich mode and inducing ΔFAS neoantigen and triggering FAS properties switch: implication in colorectal cancer.
Wu H, Hu X, Wang Y, Zhu X, Zhao Q, Zhao Y, Cui W, Zhang M, Zhao H, Li K, Wei M
Oncogene 2025 Sep;44(34):3052-3069
Oncogene 2025 Sep;44(34):3052-3069
Vimentin intermediate filaments orchestrate DNA nonhomologous end joining repair and lipolysis after DNA damage.
Wang F, Rong M, Zhang L, Solomon AD, Gui W, Li J, Wang R, Wu J, Wang L, Yang X, Peng A
Oncogene 2025 Sep;44(33):3025-3036
Oncogene 2025 Sep;44(33):3025-3036
Up-regulation of NGEF via the BRAF(V600E) /ERK/AP1 pathway enhances invasion and migration abilities of BRAF(V600E)-mutant thyroid cancer.
Fu Z, Wang Y, Wang CJ, Yu Z, Chen JQ
Biochemistry and biophysics reports 2025 Sep;43:102164
Biochemistry and biophysics reports 2025 Sep;43:102164
p62/SQSTM1 impairs immunotherapy in lung adenocarcinoma by suppressing immune infiltration and peripheral immune response.
Li H, Qin H, Xin Q, Gao J, Li S, Thomas AM, Li N, Xu L, Li M
Biochemistry and biophysics reports 2025 Sep;43:102139
Biochemistry and biophysics reports 2025 Sep;43:102139
Mechanistic Insights Into hsa_circ_0005654-Induced Ferroptosis in Diabetic Foot Ulcers Through IGF2BP2 Interaction.
Li CM, Zheng XJ, Xie SS, Lin DY, Liu ZT
The Kaohsiung journal of medical sciences 2025 Sep;41(9):e70047
The Kaohsiung journal of medical sciences 2025 Sep;41(9):e70047
SH3GL1 mediates B7-H3 recycling and enhances the immune escape in non-small cell lung cancer.
Nu Er Lan STE, Liu C
The International journal of biological markers 2025 Sep;40(3):175-186
The International journal of biological markers 2025 Sep;40(3):175-186
Insights Into the Mechanism of Action for Qingzhi Decoction for the Treatment of Non-Alcoholic Fatty Liver Disease via Regulation of the IRS/PI3K/Akt Signaling Pathway and the NRLP3 Inflammasome.
Yan J, Hou Q, Liu J, Li W
Biomedical chromatography : BMC 2025 Sep;39(9):e70156
Biomedical chromatography : BMC 2025 Sep;39(9):e70156
A Small Molecular Weight Saccharide Fraction From Panax quinquefolium L. Inhibited Non-Small Cell Lung Cancer via Endoplasmic Reticulum-Stress Mediated Apoptosis.
Lü JL, Liang J, Zhang Y, Liu XQ, Wang WF, Kuang HX, Xia YG
Phytotherapy research : PTR 2025 Sep;39(9):3868-3885
Phytotherapy research : PTR 2025 Sep;39(9):3868-3885
Study on the Effect and Mechanism of Weichang'an Pill and Its Extract on Slow Transit Constipation.
Wang N, Lu X, Gao P, Zhang P, Wang Y, Miao L, Zhang H, Chai L
Neurogastroenterology and motility 2025 Sep;37(9):e70052
Neurogastroenterology and motility 2025 Sep;37(9):e70052
Glycosylated protein-related microenvironmental features in breast cancer are associated with patient prognosis.
Zhong X, Han J, Li H, Shen X, Yu B, Chen T, Li H, Li J, Pang J, Qian L, Wu W, Tong X, Ding B
Mammalian genome : official journal of the International Mammalian Genome Society 2025 Sep;36(3):884-902
Mammalian genome : official journal of the International Mammalian Genome Society 2025 Sep;36(3):884-902
Cytotoxic effect of bladder cancer oncolytic virus on bladder cancer stem-like cells via pyroptosis pathway.
Cao X, Gao D, Zhang S, Yu X, Su X, Lu J, Wang Z
Technology and health care : official journal of the European Society for Engineering and Medicine 2025 Sep;33(5):2394-2403
Technology and health care : official journal of the European Society for Engineering and Medicine 2025 Sep;33(5):2394-2403
Integrating single-cell transcriptomics, molecular docking, and dynamics simulations to characterize protein kinase X-linked mechanisms in osteosarcoma.
Zhang Z, Sha Z, Liu Z, Cheng X, Hou Z, Wang D, Zhang Z, Gao Y
International journal of biological macromolecules 2025 Sep;325:147335
International journal of biological macromolecules 2025 Sep;325:147335
Upregulation of has_circ_0008389 promotes esophageal squamous cell carcinoma progression via miR-761 sponging and P2RY2 mRNA stabilization.
Shao Z, Xiao R, Hu B, Wu B, Zheng D, Li N
International journal of biological macromolecules 2025 Sep;323(Pt 1):147099
International journal of biological macromolecules 2025 Sep;323(Pt 1):147099
Integrative spatial multi-omics identifies the TEK receptor tyrosine kinase as a central biomacromolecule of endothelial-immune interactions in glioblastoma.
Yu Z, Zhou Q, Wang XA, Liu H, Shang R, Shen Y, Zhang J, Gao A, Liang H
International journal of biological macromolecules 2025 Sep;322(Pt 3):146964
International journal of biological macromolecules 2025 Sep;322(Pt 3):146964
C-Arg9-APCR3-VHL promotes β-catenin degradation via the VHL-mediated ubiquitin-proteasome system in APC-mutant colorectal cancer.
Luo P, Shi W, Tian L, Li Y, Cheng X, Yang J, Li Y, Dong J
International journal of biological macromolecules 2025 Sep;322(Pt 1):146678
International journal of biological macromolecules 2025 Sep;322(Pt 1):146678
IAV inhibits the host antiviral defense mediated by LncRNA-LRIR to enhance viral replication.
Chen N, Jin J, Zhao L, Liu Q, Guo Y, Deng L, Liang B, Zeng Y, Ping J
International journal of biological macromolecules 2025 Sep;322(Pt 1):146665
International journal of biological macromolecules 2025 Sep;322(Pt 1):146665
A novel glucomannan from Bletilla striata ameliorates colitis: Restores intestinal barrier, alleviates inflammation, and modulates the gut flora.
Sun X, Zhang T, Zhao Y, Yang H, Li Y, Sun X, Bian X
International journal of biological macromolecules 2025 Sep;321(Pt 3):146421
International journal of biological macromolecules 2025 Sep;321(Pt 3):146421
Rational design of a cost-effective IRES-stem-loop translation system independent of cap and poly(A) tail.
Chen Z, Sun Z, Cheng J, Ren S, He Q, Xu X, Ma Q, Weng H
International journal of biological macromolecules 2025 Sep;321(Pt 1):146218
International journal of biological macromolecules 2025 Sep;321(Pt 1):146218
DDX3X/MAVS alleviates doxorubicin‑induced cardiotoxicity by regulating stress granules.
Zhao K, Wang S, Feng D, Wang D, Yang G, Lang F
Molecular medicine reports 2025 Sep;32(3)
Molecular medicine reports 2025 Sep;32(3)
Direct effects of the small molecule PD‑L1 inhibitor BMS‑202 on A375 melanoma cells: Anti‑tumor activity accompanied by increased mitochondrial function.
Zhang N, Feng F, Dang R, Zhao X, Wang X, Yang Y, Deng J, Wang Y, Wen Z, Meng W, Huang X, Zhang S, Deng Y, Huang C, Yan P, Liu Z, Cheng X
Molecular medicine reports 2025 Sep;32(3)
Molecular medicine reports 2025 Sep;32(3)
WTAP-mediated m(6)A methylation of circRNA_404908 promotes esophageal squamous cell carcinoma progression.
Pan Y, Yang H, Zhang J, Zhang R, Yang M, Chen Q, Bie J, Liu K, Song G
The Journal of biological chemistry 2025 Sep;301(9):110512
The Journal of biological chemistry 2025 Sep;301(9):110512
Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7.
Miyauchi Y, Koba H, Sawai M, Kansui H, Takechi S, Hishinuma E, Matsukawa N, Hiratsuka M, Mackenzie PI, Ishii Y
The Journal of biological chemistry 2025 Sep;301(9):110502
The Journal of biological chemistry 2025 Sep;301(9):110502
A novel glutamine metabolism-related risk model for prognostic prediction of liver hepatocellular carcinoma.
He X, Wang R, Zhu Y, Chen X, Zhang Y, Sun M
Oncology letters 2025 Sep;30(3):403
Oncology letters 2025 Sep;30(3):403
TRIM29 promotes glioblastoma progression via ubiquitinating NEFL and activating the PI3K/AKT signaling pathway.
Liu Y, He Q, Zhu L, Zhong M, Zhuang H, Zhao N, Cai Y, Cheng C, Shao J
Cancer genetics 2025 Sep;296-297:88-99
Cancer genetics 2025 Sep;296-297:88-99
GABA ameliorates diet-induced hepatic steatosis and insulin resistance by inhibiting macrophage activation.
Cui Q, Yang Q, Wang Z, Wan Y, Jiang D, Liao Y, Du W, Ding Y, Zheng J, Li X, Li Y, Prud'homme GJ, Zhang Y, Pan B, Xu G, Wang Q
Diabetes, obesity & metabolism 2025 Sep;27(9):5085-5098
Diabetes, obesity & metabolism 2025 Sep;27(9):5085-5098
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription.
Cai Y, Zheng J, Zhao L, Wang X, Zhang L, Wang J, Zhang Y, Shi R, Han J, Han W, Chen W
Nature immunology 2025 Sep;26(9):1581-1595
Nature immunology 2025 Sep;26(9):1581-1595
Testosterone-mediated regulation of renal GSTA1/2 expression in male mice.
Hwang H, Park Y, Jeon SY, Ryu DY
Journal of veterinary science 2025 Sep;26(5):e74
Journal of veterinary science 2025 Sep;26(5):e74
TLR4 signal inhibition alleviates alkali-burn induced corneal neovascularization.
Xia C, Deng Y, Lu Y, Kang L, Wan X, Chen H, Yin X
Experimental eye research 2025 Sep;258:110486
Experimental eye research 2025 Sep;258:110486
PINK1-mediated mitochondrial autophagy protects lens epithelial cells by reducing ROS and apoptosis.
Liu X, Wang M, Ji Z, Zhu X, Tian J, Chen Y, Cai J, Dong M, Li Z
Experimental eye research 2025 Sep;258:110437
Experimental eye research 2025 Sep;258:110437
Empagliflozin Promotes Revascularization in Diabetic Mice Hindlimb Ischemia by Improving Vascular Endothelial Cell Function.
Liu H, Li Y, Zhou X, Chen T, Liu Y, Hu S, Wang C, Wang Q, Xu J, Zhou X, Shen Y, Yu C, Liu T, Wang J, Dai X
Cardiovascular toxicology 2025 Sep;25(9):1331-1343
Cardiovascular toxicology 2025 Sep;25(9):1331-1343
Benserazide‑mediated targeting hexokinase 2 enhances the cytotoxicity of cisplatin in non-small cell lung cancer cell models.
Wang K, Wang S, Shan W, Huang S, Fang T, Zhou Y, Liu L, Sha O, Tam KY
Biochemical pharmacology 2025 Sep;239:117071
Biochemical pharmacology 2025 Sep;239:117071
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Huang QH, Tang XY, Huang QY, Zhi SB, Zheng XQ, Gan CY, Huang MF, Pan ZF, Zhong ZX
Biochemical pharmacology 2025 Sep;239:117014
Biochemical pharmacology 2025 Sep;239:117014
Alexidine dihydrochloride enhances the sensitivity of human hepatocellular carcinoma to disulfidptosis via ATF4-DDIT3 activation.
Li M, Xu J, Du K, Wang G, Feng Y, Liu P
Free radical biology & medicine 2025 Sep;237:585-599
Free radical biology & medicine 2025 Sep;237:585-599
Nebulized MSC exosomes promote the transdifferentiation of transitional state cells against acute lung injury through STAT3/Krt8/AQP5 axis.
Tang Y, Qian J, Ding M, Ding R, Yang P, Dou Y
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2025 Sep;214:114792
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2025 Sep;214:114792
Endoplasmic reticulum-anchored nonstructural proteins drive human astrovirus replication organelle formation.
Bengert B, Mehri S, Holliday M, Lennemann NJ
PLoS pathogens 2025 Sep;21(9):e1013538
PLoS pathogens 2025 Sep;21(9):e1013538
IAV NS1 carried by exosomes promotes IL-10 production by the PI3K-AKT-GSK3β-CREB pathway.
Huang HM, Yang HH, Qin YC, Luo JY, Jiang ZS, Zhang ZR, Ning LJ, Li L, Wu Y
Microbial pathogenesis 2025 Sep;206:107777
Microbial pathogenesis 2025 Sep;206:107777
Comparative neurotoxic effects and mechanism of cadmium chloride and cadmium sulfate in neuronal cells.
Mei Z, Yang J, Zhao Y, Li W, Li R, Liu D, Lu H, He Z, Gu S
Environment international 2025 Sep;203:109749
Environment international 2025 Sep;203:109749
Impact of NLRP6 inflammasome on neuroinflammation in temporal lobe epilepsy.
Guo Y, Song J, Chen Y, Lü Y, Yu W
Neurochemistry international 2025 Sep;188:105994
Neurochemistry international 2025 Sep;188:105994
Overexpression of PBX1 attenuates oxidative stress and apoptosis in diabetic cardiomyopathy by transcriptionally inhibiting TXNIP.
Zhou R, Wang X, Li N
The international journal of biochemistry & cell biology 2025 Sep;186:106828
The international journal of biochemistry & cell biology 2025 Sep;186:106828
MSC-EVs alleviate sepsis-induced acute lung injury through inhibiting NET-triggered damage to adherens junctions of endothelial cells.
Shao Y, Wu D, Miao C, Zhang H
Molecular immunology 2025 Sep;185:6-17
Molecular immunology 2025 Sep;185:6-17
Evaluation of ethanolic extract of Clinacanthus nutans leaves in C2C12 myotubes: anti-exercise fatigue activity.
Lyu R, Shi J, Xiao X, Gu W, Chen J, Wu X, Wang J, Liu C
Fitoterapia 2025 Sep;185:106643
Fitoterapia 2025 Sep;185:106643
PPARγ is a potential therapeutic target for radiation enteritis via suppressing ferroptosis, mediated by the GAPDH/glycosylation axis.
Zeng X, Zhang L, Lu H, Xue X, Yang L, Yang X, Liu Z, Cao X, Dai Y, Wei Z
British journal of pharmacology 2025 Sep;182(17):3994-4019
British journal of pharmacology 2025 Sep;182(17):3994-4019
Association of elevated ACSL4 expression with impaired endometrial receptivity in endometriosis and restoration by ACSL4 inhibitor PRGL493.
Xu L, Wei H, Shang Y, Yang Q
Journal of reproductive immunology 2025 Sep;171:104630
Journal of reproductive immunology 2025 Sep;171:104630
Reduced level of BMI1 inhibits trophoblast proliferation and migration via the epigenetic enhancement of CSTA and TGFB2 in spontaneous abortion.
Li H, Wang G, Meng Q, Zhu R, Liu M, Zhang X, Wang J, Li H
Placenta 2025 Sep;169:82-93
Placenta 2025 Sep;169:82-93
Zebrafish CD44a variants suppress antiviral immunity through regulation of RIG-I ubiquitination and degradation.
Cao L, Chang MX
Fish & shellfish immunology 2025 Sep;164:110442
Fish & shellfish immunology 2025 Sep;164:110442
SUMO E1 covalent allosteric inhibitors upregulate polyamine synthesis via the MAT2A-AdoMetDC axis.
Zhang S, Li J, Wang Z, Jiao Y, Shi X, Ai Y, Wang J, Liu S
Bioorganic chemistry 2025 Sep;164:108930
Bioorganic chemistry 2025 Sep;164:108930
Optimized synthesis of 5N-D and the exploration of its role as a promising anti-aging agent via AKR1B1 inhibition and PI3K/Akt/Nrf2 regulation.
Liu L, Wang C, Chen Z, Yin M, Zhang K, Zhang C, Peng S, Li M, Jiang S, Chen H
Bioorganic chemistry 2025 Sep;164:108886
Bioorganic chemistry 2025 Sep;164:108886
Development of Adamantane-based hydrophobic tags targeting anaplastic lymphoma kinase with enhanced antitumor activities.
Zhu J, Zhan F, Xie J, Fang T, Sun Y, Zhan F, Gao T, Liu J, Feng J, Zhou P, Zhu H, Yao H, Zhu Z, Xu S, Xu J, Xie S
Bioorganic chemistry 2025 Sep;164:108876
Bioorganic chemistry 2025 Sep;164:108876
Design, synthesis, and biological evaluation of Pseudolaric acid B derivatives as Ferroptosis inducers in Colon Cancer cells.
Zhang L, Wang YX, Chen JZ, Bao F, Tan QM, Li YL, Kong LY, Luo JG, Chen C
Bioorganic chemistry 2025 Sep;164:108852
Bioorganic chemistry 2025 Sep;164:108852
Energy metabolism disturbance induced by atorvastatin exposure on yellowstripe goby (Mugilogobius chulae) larvae based on transcriptome and metabolome analysis.
Zhao Y, Wang Y, Gong W, Duan C, Ren J, Zhang H, Nie X
Journal of environmental sciences (China) 2025 Sep;155:475-487
Journal of environmental sciences (China) 2025 Sep;155:475-487
Carbon black induced pulmonary fibrosis through piR-713551/PIWIL4 targeting THBS2 signal pathway.
Wang M, Niu Y, Liu Q, Yang P, Wu M, Wu R, Shi B, Chen J, Wang J, Du Z, Pang Y, Bao L, Niu Y, Zhang R
Journal of environmental sciences (China) 2025 Sep;155:409-422
Journal of environmental sciences (China) 2025 Sep;155:409-422
Irisin/FNDC5 Regulates Endothelial Function to Improve Post-Stroke-Induced Cognitive Dysfunction by Stimulating AMPK-eNOS Signaling.
Guo HH, Liang JJ, Pan RH, Zheng MF, Qiu YX, Jiang SS, Fu XY, Tsang HW, Yau SY, Ou HN
Brain and behavior 2025 Sep;15(9):e70767
Brain and behavior 2025 Sep;15(9):e70767
Celastrol protected the MPTP-injected mice Parkinson's disease model via redox regulation of CDC37.
Liao W, Dong A, Hafeez F, Ye Q, Huang E
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157067
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157067
Danggui buxue decoction attenuates doxorubicin-induced cardiotoxicity by inhibiting ZBP1-mediated PANoptosis in vivo and in vitro.
Zhang L, Kong HW, Song XY, Sheng LS, Huang NN, Liu Y, Sun R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157037
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157037
Salidroside alleviates bone cancer pain by inhibiting Th17/Treg imbalance through the AMPK/SIRT1 pathway.
Zheng K, Yang C, Han M, Kang F, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157000
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157000
Multi-omics analysis of the active components and mechanisms of Baojin Chenfei formula in silica-induced murine silicosis.
Wr H, Yq L, Xg L, Yf Z, Y W, P Z, Js L, Q Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156986
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156986
Ginger-processed Magnoliae Officinalis Cortex ameliorates ovalbumin-induced asthma by alleviating inflammation via the gut-lung axis.
Li J, Hu J, Zhuo D, Yang L, Wang L, Yang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156971
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156971
Tanshinone IIA attenuates sepsis-induced lung injury by reducing VEGFR2/PI3K/AKT-driven mitochondrial disruption dependent apoptosis.
Aidebaike D, Gong H, Xia Y, Jing G, Liu H, Zhou H, Wu D, Zuo J, Yang C, Wang X, Dong Y, Yan J, Chen X, Lei Z, Liang J, Wu X, Song X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156957
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156957
Proteomics analysis and immune profiling reveal regulators of PD-L1 in oesophageal squamous cell carcinoma.
Li Y, Yuan X, Yin XF, Zheng D, Shi F, Liu D, Hu L, Shi X, Wen N, He QY, Yang H, Zhang CZ
British journal of cancer 2025 Sep;133(4):448-463
British journal of cancer 2025 Sep;133(4):448-463
Donkey Milk Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis by Protecting Gut Barrier Function, Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway, and Modulating Gut Microbiota.
Yang L, Ni H, Gou X, Zhong B, Wen K, Zhang Y, Zhang S, Wang Y
Food science & nutrition 2025 Sep;13(9):e70989
Food science & nutrition 2025 Sep;13(9):e70989
Protective Effects of Ganoderma Triterpenoids Supplementation Against Myocardial Injury in Exhaustion Exercise Mice via Regulation of the Keap1/Nrf2/HO-1 Pathway.
Li J, Zhang L, Qin G, Liu W, Xu X, Zhu J, Zhao S, Qiu T
Food science & nutrition 2025 Sep;13(9):e70937
Food science & nutrition 2025 Sep;13(9):e70937
Inhibition of Iron Death by Lycium barbarum Polysaccharides Ameliorates Myocardial Injury in Sepsis: A Pharmacological Mechanism Study Based on the NRF2/HO-1 Pathway.
Niu Z, Hu Y, Yang L, Meng X, Chen M, Bai X, Liu R, Tang Y, Yang L, Xue W
Food science & nutrition 2025 Sep;13(9):e70835
Food science & nutrition 2025 Sep;13(9):e70835
Dual-mode immunotherapy: ultrasound responsive zinc-based nano-contract agents synergistically activate the GAS-STING pathway for enhanced tumor sono-metalloimmunotherapy.
Zeng X, Wang X, Zhao Y, Guo L, Sun X, Shang M, Huang S, Liu R, Zhang J, Xiao S, Shi D, Cong N, Li J
Ultrasonics sonochemistry 2025 Sep;120:107494
Ultrasonics sonochemistry 2025 Sep;120:107494
SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1-Mediated Transactivation of CD47.
Liu Z, Zhao X, Zang M, Yuan H, Qin X, Li X, Zhao S, Tan R, Yan K, Liu L, Fan Y, Zhang N, Shi B, Han B, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e04200
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e04200
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Wang T, Han L, Huo Y, Zhang L, Huang Y, Zhang N, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer.
Yan Y, Wang N, Xing B, Yang M, Shang J, Bao Y, Xiao L, Zhang N, Ren Y, Liu C, Chen Y, Han H, Pan Y, Lv L, Zong WX, Ji H, Zhan C, Wang Z, Chen H, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e03322
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e03322
Vimentin intermediate filaments facilitate transportation of hepatitis C virus components.
Xing Y, Cui S, Huang X, Zhao W, Li H, Zhao J, Chang W, Zhao S, Zhong J, Chen Y, Jiu Y
European journal of cell biology 2025 Sep;104(3):151505
European journal of cell biology 2025 Sep;104(3):151505
Sfrp2-deficient colonic fibroblasts drive mucosal inflammation and epithelial injury in ulcerative colitis.
Zhu M, Diao Z, Hu L, Fan Z
Cellular immunology 2025 Sep-Oct;415-416:105003
Cellular immunology 2025 Sep-Oct;415-416:105003
Enhancing the antitumor activity of CD19/BCMA CAR-T cells in vitro with a PD1IL7R chimeric switch receptor.
Yan K, Xiao Z
Cellular immunology 2025 Sep-Oct;415-416:105001
Cellular immunology 2025 Sep-Oct;415-416:105001
Cryptococcus neoformans and the EGFR Puzzle: Uncovering a Novel mechanism for blood-brain barrier crossing.
Zhao J, Fang W, Gao Y, Fa Z, Wang G, Gu J
Microbes and infection 2025 Sep-Oct;27(7):105540
Microbes and infection 2025 Sep-Oct;27(7):105540
5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
Li J, Lu Y, Hu H, Han X, Pan Y, Sun K, Liu K, Yu Z
Lasers in medical science 2025 Sep 9;40(1):353
Lasers in medical science 2025 Sep 9;40(1):353
Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair.
Xiong W, Liu M, Wang J, Liu J, Zheng M, Chan P, Zhu Q, Li C, Kong G, Tang C, Fan J
ACS nano 2025 Sep 9;19(35):31551-31571
ACS nano 2025 Sep 9;19(35):31551-31571
TMAO regulates OTUB1-mediated SLC7A11 stability to promote NAFLD progression.
Zhong B, Zhu Q, Wei P, Wang X
Biochemical and biophysical research communications 2025 Sep 8;778:152352
Biochemical and biophysical research communications 2025 Sep 8;778:152352
Lidocaine intervention attenuated postoperative delirium by reshaping intestinal flora and modulating microglia M2 type polarization and blood-brain barrier.
Xie F, Du Q, Wang Q, Lu W, Song S, Yu J
Biochemical and biophysical research communications 2025 Sep 8;778:152301
Biochemical and biophysical research communications 2025 Sep 8;778:152301
Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity.
Xu Y, Lou D, Chen P, Li G, Usoskin D, Pan J, Li F, Huang S, Hess C, Tang R, Hu X, Yu J, Arceo M, de Krijger RR, Tischler AS, Schlisio S, Ernfors P, Hu Y, Wang J
Developmental cell 2025 Sep 8;60(17):2248-2263.e11
Developmental cell 2025 Sep 8;60(17):2248-2263.e11
A Preliminary Study of the Relationship Between Zinc and the AhR Signaling Pathway During Palatal Development.
Liang S, Zhai Y, Chen Z, Yang J, Shu X, Luo J, Wang N, Wang F, Song Q
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2025 Sep 8;:10556656251375952
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2025 Sep 8;:10556656251375952
A Novel Nuclear-Localized Micropeptide, MP60, Promotes Hepatocellular Carcinoma Progression via the Epithelial-Mesenchymal Transition.
Li C, Hong X, Setrerrahmane S, Sun X, Zhang X, Xu H
Cancers 2025 Sep 7;17(17)
Cancers 2025 Sep 7;17(17)
Study on the role of FN1 in chronic obstructive pulmonary disease.
Wang F, Zhang J, Yuan Y, Zhou J, Pang S, Li X, Qiu A
Gene 2025 Sep 5;963:149551
Gene 2025 Sep 5;963:149551
Epigenetic reprogramming of HDAC2 in CA1 excitatory neurons determines Pb-induced non-spatial memory deficits.
Wang M, Huang C, Ai S, Xia Y, Li C, Zhi Y, Wang K, Nie M, Gu X, Xu Y, Zhang H, Wang HL
Journal of hazardous materials 2025 Sep 5;495:138818
Journal of hazardous materials 2025 Sep 5;495:138818
Design, synthesis and biological evaluation of triazolothiadiazole derivatives as FSP1 inhibitors for sensitizing cancer cells to ferroptosis.
Liu W, Xie X, Zong H, Li Y, Ding Y, Liu Z, Wan B, Xiao T, Lv F, Tang C, Yu L, Wang P, Lai Z
European journal of medicinal chemistry 2025 Sep 5;293:117737
European journal of medicinal chemistry 2025 Sep 5;293:117737
Hydroxysafflor yellow A alleviates ischemic myocardial injury by targeting SF3A1 to improve mitochondrial energy metabolism.
Wang BK, Wang R, Zhuo FF, Wang JK, Huang YL, Tu PF, Zeng KW, Li J
European journal of pharmacology 2025 Sep 5;1002:177789
European journal of pharmacology 2025 Sep 5;1002:177789
KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1.
Wang X, Bai Z, Wallis C, Wang H, Han Y, Jin R, Lei M, Yang T, Gu C, Jessen H, Shears S, Sun Y, Corry B, Zhang Y
Molecular cell 2025 Sep 4;85(17):3209-3224.e8
Molecular cell 2025 Sep 4;85(17):3209-3224.e8
Artemisinin alleviates Parkinson's disease by targeting Adcy5-Gch1 axis to trigger a cascade generation of BH4 and dopamine in rats.
Yang XX, Wang GQ, Wen Q, Zhao YJ, Li DD, Zhang F
Genome biology 2025 Sep 4;26(1):267
Genome biology 2025 Sep 4;26(1):267
ROS and Drp1-mediated mitochondrial fission contributes to the hyposalivation caused by Sjögren's disease.
Zhang Y, Du Z, Zhang S, Chu W, Ding C, Shan X
Chinese medical journal 2025 Sep 4;
Chinese medical journal 2025 Sep 4;
Peripheral blood mesenchymal stem cells repair oxidative damage and apoptosis in an H(2)O(2)-induced vitiligo oxidative stress in vitro model via the IL-10-mediated PI3K/AKT pathway.
Yang RL, Yang YB, Wei HX, Zhang M, Yang K, Zhao YJ, Yan W, Yang Y, Zhang T
European journal of medical research 2025 Sep 30;30(1):919
European journal of medical research 2025 Sep 30;30(1):919
Circular RNA hsa_circ_0006522 correlates with unfavorable prognosis and promotes the proliferative, migrative, and invasive abilities of breast cancer cells.
Wang X, Zhang P, Bai Z, Meng L, Zheng Y, Sang M, Geng C
Translational cancer research 2025 Sep 30;14(9):5823-5837
Translational cancer research 2025 Sep 30;14(9):5823-5837
Constructing a chemokine-based model and identifying CCL17 as a core biomarker associated with immune infiltrates in thyroid cancer.
Zhang M, Zou B, Li Q, Zhao Y, He Y
Translational cancer research 2025 Sep 30;14(9):5720-5744
Translational cancer research 2025 Sep 30;14(9):5720-5744
N6-adenosine methyltransferase METTL4 is a potential prognostic biomarker and associates with cell cycle regulation and immune infiltration in glioma.
Zhang S, Huang Z, Sun S, Feng S, Liu K, Sang L, Yang J, Yang F, Zhang R, Fan H, Guo H
Translational cancer research 2025 Sep 30;14(9):5520-5533
Translational cancer research 2025 Sep 30;14(9):5520-5533
Lactobacillus johnsonii-derived extracellular vesicles restore mucosal immunity via taurine-linked Th17/Treg and IgA/IgG regulation in colitis.
Zhao H, Yue N, Mai Z, Zhang Y, Tian C, Kong C, Huang L, Shi R, Liang Y, Yao J, Nie Y, Li D, Nie B, Wang L
Journal of nanobiotechnology 2025 Sep 29;23(1):612
Journal of nanobiotechnology 2025 Sep 29;23(1):612
ATG7-induced autophagy inhibits ferroptosis and promotes the progression of colorectal adenocarcinoma.
Chen M, Meng Z, Zhu L, Liu J
Discover oncology 2025 Sep 29;16(1):1755
Discover oncology 2025 Sep 29;16(1):1755
Novel Pathogenic Biallelic Variants in KIAA0586 Expand the Variant Spectrum of Ciliopathies.
Shen Y, He R, Lu C, Wang Z, Yu Y, Cao Z, Luo M
Cytoskeleton (Hoboken, N.J.) 2025 Sep 29;
Cytoskeleton (Hoboken, N.J.) 2025 Sep 29;
Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway.
Du W, Xu R, Chen P, Wen J, Sun L, Chen X
Nutrients 2025 Sep 28;17(19)
Nutrients 2025 Sep 28;17(19)
Research on the inhibitory effect of hydrogen gas on ovarian cancer and potential mechanisms.
Yin M, Liu M, Zhang C, Peng L, Guo Z, Hao Y, Wang Y, Zhang X, Shi Q, Ren X, Li H, Zhang L
European journal of medical research 2025 Sep 26;30(1):874
European journal of medical research 2025 Sep 26;30(1):874
Differential regulation of mesoscale chromosome conformations in osteoblasts and osteosarcoma.
Bisht M, Chung YC, He SL, Willey S, Sunkel BD, Wang M, Stanton BZ, Tu LC
Genome biology 2025 Sep 26;26(1):307
Genome biology 2025 Sep 26;26(1):307
Identification of a dihydroartemisinin-related prognostic signature and its contribution to cancer associated fibroblast of the tumor microenvironment of pancreatic cancer.
Lai J, Zhong T, Zhang C, Fang C, Lei D, Xie Y, Liu X, Lai Z, Yan Z, Ai W, Qu J, Zheng B
BMC gastroenterology 2025 Sep 26;25(1):656
BMC gastroenterology 2025 Sep 26;25(1):656
PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis.
Zhou C, Zhang J, Chen L, Yu Y, Sun Y, Pan Y, Cai S, Zhong P
BMC oral health 2025 Sep 26;25(1):1472
BMC oral health 2025 Sep 26;25(1):1472
Comparison of Quercetin and Isoquercitrin's Anti-Heart Failure Activity via MAPK Inflammatory Pathway and Caspase Apoptosis Pathway.
Guo A, Chen X, Bai Y, Dai Y, Yue H
Pharmaceuticals (Basel, Switzerland) 2025 Sep 26;18(10)
Pharmaceuticals (Basel, Switzerland) 2025 Sep 26;18(10)
Harnessing indole scaffolds to identify small-molecule IRE1α inhibitors modulating XBP1 mRNA splicing.
Liu Y, Avathan Veettil AK, Gasper R, Jiang M, Wagner L, Hastürk O, Wu P
Nature communications 2025 Sep 26;16(1):8531
Nature communications 2025 Sep 26;16(1):8531
Mechanisms of Saposhnikovia divaricata in attenuating NaAsO(2)-induced neural injury via the PI3K/AKT pathway.
Gu D, Chen XL, He HL, Xia M, Huang JY, He GH, Wang XY, Chen YY, Kang WR, Sun BF, Liu XH, Zhou W, Zhuo XL, Pan JG
Scientific reports 2025 Sep 26;15(1):33303
Scientific reports 2025 Sep 26;15(1):33303
Unveiling the genetic biomarkers for ageing: evidence from a large sample genome-wide association study and in vivo validation.
Cai Z, Yang Y, Qu P, Fu S, Li X
Journal of global health 2025 Sep 26;15:04279
Journal of global health 2025 Sep 26;15:04279
The synergistic administration of sanguinarine and curcumin ameliorates indomethacin-induced small intestinal injury in rats through the modulation of Nrf2 and NF-κB signaling pathways.
Lin X, Zhou Y, Xia L, Chen M, Liao W, Yang X, Tuo Q, Lin L, Liao D, Zeng J
Biochemical and biophysical research communications 2025 Sep 25;781:152551
Biochemical and biophysical research communications 2025 Sep 25;781:152551
Rutaecarpine alleviates liver fibrosis by modulating the TRPV1/Connexin 43 axis: A study based on transcriptome data, single-cell sequencing data, and cell experiments.
Zhao Y, Wu XQ, Liao SL
Biochemical and biophysical research communications 2025 Sep 25;781:152506
Biochemical and biophysical research communications 2025 Sep 25;781:152506
ComplexDnet: A Network-Based Strategy to Discover Critical Targets and Screen Active Compounds for Complex Diseases.
Pan F, Xu ZM, Liu ZH, Chen CY, Yu JW, Wu ZR, Wang Z, Chen L, Yue CY, Li WH, Liu GX, Huang J, Tang Y
Journal of medicinal chemistry 2025 Sep 25;68(18):19463-19481
Journal of medicinal chemistry 2025 Sep 25;68(18):19463-19481
Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis-infected bovine mammary epithelial cells identifies proteins and miRNAs that induce inflammatory responses in macrophages.
Wu Y, Yuan X, Ma J, Xu L, Li M, Zhao G, Wang Y
Veterinary research 2025 Sep 25;56(1):185
Veterinary research 2025 Sep 25;56(1):185
Dynamic U2AF cycling defines two phases of cotranscriptional pre-mRNA splicing.
Shao C, Hao Y, Jiang L, Wang D, Wang R, Li Y, Wang H, Ge Y, Bai R, Du X, Chen X, Wu T, Gou LT, Wan R, Xu Y, Ji X, Fu XD
Science (New York, N.Y.) 2025 Sep 25;389(6767):eadj9141
Science (New York, N.Y.) 2025 Sep 25;389(6767):eadj9141
Systematic reevaluation on the antipyretic, analgesic effects, and uncover the mechanisms of Chaiqin Qingning capsule, a traditional Chinese medicine, via establishing lipopolysaccharide - induced fever models, physical and chemical - stimuli pain models.
Huang L, Gao H, Halihaman B, Li C, Ding X
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120432
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120432
Fufang epimedium formula alleviates acute liver injury through dual modulation of PI3K/AKT/Bcl-2 anti-apoptotic signaling pathway and cGAS-STING-IRF3 anti-inflammatory signaling pathway.
Feng Y, Yusufu R, Chen T, Guan Z, Zhang L, Li S, Luo M, Jiang H, Wei F
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120415
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120415
Aurantii Fructus alleviates depression via modulating hippocampal caspase-4-linked neurogenesis and synaptic plasticity in mice.
Wu L, Tian L, Wei Z, Jiang Y, Shao M, Zhu Y, Sun Y, Lu C
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120406
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120406
Atractylenolide III attenuates acute kidney injury through phosphorylation of PIK3CA: Functional activation and molecular interaction analysis.
You J, Sun S, Lv D, Fan S, Yan X, Liu M, Jin J, Wang W
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120368
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120368
The therapeutic mechanisms of Compound Kushen Injection in relieving cancer-induced bone pain by targeting Nav1.7 and microglial activation.
Gao L, Li QW, Zhang XY, You RL, Qin XM, Qin WJ
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120367
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120367
Tianlong kechuanling ameliorated COPD-PH through DNMT3A-GSDMD axis-dependent regulation of endothelial cell pyroptosis.
Li H, Li Z, Gong J, Yan Y, Cui X, Yu Q, Shi Y, Tian X, Jiang Q, Tan Z, Yang Y, Zhou W, Ding Q, Wang P
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120332
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120332
Shenling Baizhu Powder and Betulin attenuate sepsis-induced intestinal injury by targeting GADD45B/TAOK1/p38 MAPK pathway.
Xia G, Shen C, Xiao Y, Wang X, Qiu L, Lei S, Jiang R
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120282
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120282
In-depth investigation of the mechanism in rats with alcoholic acute pancreatitis via DNA methylation, intestinal flora, and fecal metabolomics.
Dong H, Ying W, Zhu S
Journal of inflammation (London, England) 2025 Sep 25;22(1):37
Journal of inflammation (London, England) 2025 Sep 25;22(1):37
NCAPH-YAP1 interaction promotes breast cancer stemness and tumor progression.
Qiu C, Wei Y, Li J
Stem cell research & therapy 2025 Sep 25;16(1):494
Stem cell research & therapy 2025 Sep 25;16(1):494
METTL3-Driven m6A Epigenetic Remodeling of lncRNA-AU020206 Stabilizes SLC7A11 via YTHDC2 Attenuates Apoptosis and Ferroptosis in Cerebral Ischemia/Reperfusion Injury.
Zhang H, Guan Y, Li M, Wu Y, Sun X
Biomolecules 2025 Sep 24;15(10)
Biomolecules 2025 Sep 24;15(10)
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y
Bone research 2025 Sep 24;13(1):79
Bone research 2025 Sep 24;13(1):79
ARRDC1 inhibits the replication of Semliki Forest virus by regulating the ubiquitination and degradation of viral nsP4.
Peng Q, Yang X, Chen C, He J, Liang Y, Luo X, Huang C, Wu W, Zhang P, Liu C
Journal of virology 2025 Sep 23;99(9):e0097725
Journal of virology 2025 Sep 23;99(9):e0097725
taVNS alleviates preeclampsia-induced vascular endothelial dysfunction via α7nAChR- IP3R1/GRP75/VDAC1 signal pathway.
Zhao J, Lei Y, Mu C, Wu Y, Fang R, Wu D, Xu S, Qiao H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Sep 23;74(1):133
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Sep 23;74(1):133
YTHDF1-mediated mitochondrial dysfunction and allergic airway inflammation by interaction with β-catenin/TCF4 signaling.
Xie C, Huang J, Chen Y, Huang B, Chen Y, Li Y, Gong Z, Ma Y, Xu M, Fan K, Hu D, Zhao X, Huang P, Peng X, Cai S, Zhao W, Zhao H
International immunopharmacology 2025 Sep 23;162:115181
International immunopharmacology 2025 Sep 23;162:115181
Fluzoparib disrupts Golgi apparatus to inhibit O-GlcNAcylation and nuclear translocation of β-catenin to attenuate ovarian cancer invasion and metastasis.
Peng J, Liu J, Ning M, Han W, Wang H, Wang Z, Hong L, Liu C
International immunopharmacology 2025 Sep 23;162:115158
International immunopharmacology 2025 Sep 23;162:115158
Colla Corii Asini regulate collagen regeneration in UV exposure-induced skin photoaging in mice.
Ma Y, Huang J, Gong J, Li L, Zhao Y, Jin Y, Gu J, Liu H, Wang Y, Sun Y
Chinese medicine 2025 Sep 22;20(1):146
Chinese medicine 2025 Sep 22;20(1):146
Sheng Mai San Mitigates Heat Stress-Induced Myocardial Injury by Coordinated Regulation of the Keap1-Nrf2-HO-1 and Stub1-HSF1 Signaling Pathways.
Dong J, Ma Q, Yang R, Zhang X, Hua Y, Ji P, Yao W, Yuan Z, Wei Y
Antioxidants (Basel, Switzerland) 2025 Sep 22;14(9)
Antioxidants (Basel, Switzerland) 2025 Sep 22;14(9)
Lumpy Skin Disease Virus ORF137 Protein Inhibits Type I Interferon Production by Interacting with and Decreasing the Phosphorylation of IRF3.
Ke Q, Yao K, Qu M, Liang Z, Li M, Wang X, Yin X, Sun Y
Cells 2025 Sep 22;14(18)
Cells 2025 Sep 22;14(18)
Cytoplasmic localization of PUS7 facilitates a pseudouridine-dependent enhancement of cellular stress tolerance.
Ruan M, Engels SM, Burroughs MR, Li X, Stower R, Tzadikario T, Powell C, Bloch D, Fanari O, Akeson S, Eyler DE, Weidmann CA, Rouhanifard S, Jain M, Contreras LM, Koutmou KS
bioRxiv : the preprint server for biology 2025 Sep 22;
bioRxiv : the preprint server for biology 2025 Sep 22;
Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson's Disease Model: Transcriptomic Evidence.
Lyu P, Wen F, Fu Z, Li J, Li Q, Cai X, Huang S, Qiu X, Zhang Z, Huang Y, Zhang J
Journal of integrative neuroscience 2025 Sep 18;24(9):40105
Journal of integrative neuroscience 2025 Sep 18;24(9):40105
ZNF180 modulates tumor intrinsic immunotherapy resistance in melanoma through driving plasticity.
Song WM, Kondapuram SK, Zhou X, Chen SH, Agrawal P
bioRxiv : the preprint server for biology 2025 Sep 18;
bioRxiv : the preprint server for biology 2025 Sep 18;
Chronic Exposure to Sunset Yellow Promotes Susceptibility to Experimental Colitis in Mice through Gut Microbiota.
Shi X, Wan L, Ni S, Wu X, Mu J, Pei W, Chen Z, Xia Y, Li L, Zhang Z
Journal of agricultural and food chemistry 2025 Sep 17;73(37):23633-23643
Journal of agricultural and food chemistry 2025 Sep 17;73(37):23633-23643
Metallothionein 2A-Silencing Antimonene-Based Nanoagonist for Amplifying the Photothermal Immunotherapy of Gynecologic Malignancy.
Shen C, Huang F, Wang Y, Dai Y, Chen J, Chen Y, Huang Z, Zhang Y, Weng L, Luo Z, Hu Y, Wang L
ACS nano 2025 Sep 16;19(36):32306-32321
ACS nano 2025 Sep 16;19(36):32306-32321
Multi-Omics Insights into Postnatal Skeletal Muscle Development in Duroc Pigs.
Wang K, Li X, Liu X, Liufu S, Xiao L, Chen B, Chen W, Jiang J, Liu Y, Ma H
Animals : an open access journal from MDPI 2025 Sep 16;15(18)
Animals : an open access journal from MDPI 2025 Sep 16;15(18)
S-nitrosylation of pVHL regulates β(2) adrenergic receptor function.
Grimmett ZW, Hayashi H, Raffay TM, Lin J, Premont RT, Stamler JS
Proceedings of the National Academy of Sciences of the United States of America 2025 Sep 16;122(37):e2515326122
Proceedings of the National Academy of Sciences of the United States of America 2025 Sep 16;122(37):e2515326122
Angptl4 is upregulated by microenvironmental factors during the wound healing process and promotes epidermal stem cell proliferation via PRL8a6.
Yu S, Ji P, Du T, Liu Z, Yang Y, Lv Z, Xu L, Jin Q, Gong W, Le Y, Fu Y, Hou R
Acta biochimica et biophysica Sinica 2025 Sep 15;57(12):1969-82
Acta biochimica et biophysica Sinica 2025 Sep 15;57(12):1969-82
Podoplanin-TGF-β1 Autocrine Loop: Pivotal Regulator of Islet Stellate Cell Activation via Cell Deformation, Orchestrating Islet Fibrosis in Diabetes.
Wang X, Wang Q, Yuan Y, Ni C, Cai Z, Qiu S, Li T, Chen Y, Wang J, Wang H, Carvalho V, Sun Z, Liu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70970
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70970
African swine fever virus pNP419L inhibits type I interferon signaling by blocking ISGF3-mediated transcriptional activation.
Chen Q, Liu L, Wu W, Li L, Yu Z, Liu Q, Wang D, Tan C, Chen H, Wang X
International journal of biological macromolecules 2025 Sep 15;328(Pt 2):147704
International journal of biological macromolecules 2025 Sep 15;328(Pt 2):147704
Based on disulfide accumulation, leveraging a THBS1-signature to improve the outcome of head and neck carcinoma patients.
Jin Y, Wang Z, Zhou C, Wen M, Zhou Y, Huang S
International journal of biological macromolecules 2025 Sep 15;328(Pt 2):147679
International journal of biological macromolecules 2025 Sep 15;328(Pt 2):147679
Human umbilical cord mesenchymal stem cell -derived exosomes alleviated the toxic effects induced by lead on HK-2 cells via regulating the unfolded protein response.
He J, Hu Z, Gao Z, Liu R, Kang Z, Lan S, Wang Y, He S, Xian H, Diallo F, Jiang Y, Wu J, Huang S, Lv Z, Hu D
Ecotoxicology and environmental safety 2025 Sep 15;303:119006
Ecotoxicology and environmental safety 2025 Sep 15;303:119006
Exploring the potential mechanisms of Jinglinzi powder in treating hepatocellular carcinoma based on LC-MS, network pharmacology, molecular docking, and experimental validation.
Liu G, Kuang S, Zhong W, Yang A, Huang X, Xie Y, Zhang X, Li Y, Qin Q, Liu G
Journal of pharmaceutical and biomedical analysis 2025 Sep 15;263:116899
Journal of pharmaceutical and biomedical analysis 2025 Sep 15;263:116899
Methionyl-tRNA synthetase 1 participates in hepatocellular carcinoma and its regulated gene profile possesses potent prognostic ability.
Bu HY, Huang H, Li J, Huang ZB, Huang Y, Huang YK, Wang AM, Wu L, Yuan J, Wang RJ, Lu M, Yu SM, Yi PP, Chen YY, Jiang YP, Hu XW
World journal of gastrointestinal oncology 2025 Sep 15;17(9):109127
World journal of gastrointestinal oncology 2025 Sep 15;17(9):109127
Dietary 1,3-diacylglycerol ameliorates hyperuricemia via dual modulation of urate transporters and inflammasomes in mice.
Zhang Y, Huang L, Liu R, Jiang J, Li H, Chen S, Wu G, Liu K
Food & function 2025 Sep 15;16(18):7253-7265
Food & function 2025 Sep 15;16(18):7253-7265
Hydroxypropyl-β-cyclodextrin inclusion complex improves the percutaneous therapeutic effect of eugenol on psoriasis mice.
Guo Y, Yue Y, Wang H, Zhong Z, Chen B, Shu L, Wang J, Zhang Z
European journal of pharmacology 2025 Sep 15;1003:177921
European journal of pharmacology 2025 Sep 15;1003:177921
Inhibition of GRK2 mitigates renal fibrosis via oxidative stress pathway.
Cheng J, Jiang X, Deng Q, Ni L, Lin W, Cao W, Ren P, Xu B, Wang Q, Kuai J, Wu Y, Wei W, Wang C
European journal of pharmacology 2025 Sep 15;1003:177887
European journal of pharmacology 2025 Sep 15;1003:177887
Integrative proteomic characterization of human lung adenocarcinoma with KRAS G12 mutations reveals molecular pathogenesis.
Shi X, Hu L, Huang Y, Zhang MF, Ying X, Yuan X, Wen N, Lu J, Zou H, Tan X, He QY, Wang F, Yang H, Zhang CZ
Journal of advanced research 2025 Sep 14;
Journal of advanced research 2025 Sep 14;
MAO-A inhibition alleviates sepsis-driven lung injury via Nrf2/HO-1 pathway activation and suppression of pyroptosis.
Li M, Li H, Gong L, Chen X, Dai J, Tian J, Yin X, Yu Q
Journal of molecular histology 2025 Sep 13;56(5):310
Journal of molecular histology 2025 Sep 13;56(5):310
Effects on Oral Squamous Carcinoma Cell Lines and Their Mechanisms of Pyrazole N-Aryl Sulfonate: A Novel Class of Selective Cyclooxygenase-2 Inhibitors.
Wang S, Shi M, Wang H, Zeng X, Zhang D, Zhang Z, Xu Z, Li Y
International journal of molecular sciences 2025 Sep 12;26(18)
International journal of molecular sciences 2025 Sep 12;26(18)
Oligomeric Proanthocyanidins Reverse Lenvatinib Resistance in Hepatocellular Carcinoma Through ITGA3-Mediated Pathway.
Noma T, Li Y, Wada Y, Morine Y, Ikemoto T, Saito Y, Yamada S, Teraoku H, Shimada M, Goel A
Pharmaceuticals (Basel, Switzerland) 2025 Sep 12;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Sep 12;18(9)
Time-Restricted Feeding Affects Energy Metabolism in Lactating Striped Hamsters (Cricetulus barabensis, Cricetidae, Rodentia).
Li W, Dong X, He J, Jin X, Yin B, Bo T, Wen J
Biology 2025 Sep 12;14(9)
Biology 2025 Sep 12;14(9)
Mechanistic study on the inhibition of triple-negative breast cancer progression by LncRNA TFAP2A-AS1 through the regulation of miR-6892/PHGDH.
Yuan L, Yuan J, Zhang S, Wei C, Luo C
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Sep 10;74(1):121
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Sep 10;74(1):121
Strontium-Loaded Chitosan/Wood Hydrogel with Anisotropic Cellular Architecture for Enhanced Critical Bone Regeneration.
Zhang M, Yang J, Zhang J, Wo K, Dong X, Deng H, Wang M, Yang C
ACS applied materials & interfaces 2025 Sep 10;17(36):50302-50316
ACS applied materials & interfaces 2025 Sep 10;17(36):50302-50316
11β-HSD1 inhibitor alleviates sepsis-induced cardiac dysfunction by regulating macrophage polarization via the AMPK/mTOR autophagy pathway.
Zhang Z, Yin B, Zhu D, Wu D, Huang M, Zhou S
Journal of cardiology 2025 Sep 10;
Journal of cardiology 2025 Sep 10;
Prognostic significance of BATF family genes and correlation with immune infiltration in colorectal cancer.
Tang K, Han C, Duan B, Zhu H, Yang H
Biochemical and biophysical research communications 2025 Sep 1;777:152313
Biochemical and biophysical research communications 2025 Sep 1;777:152313
N-acetyltransferase 10 Promotes Pancreatic Cancer Progression Through ZEB1/MT1-MMP Axis.
Wang F, Hu Y, Zhang S, Ye Y, Qi H, Xu Y, Zhang H, Liu M
Pancreas 2025 Sep 1;54(8):e674-e683
Pancreas 2025 Sep 1;54(8):e674-e683
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
Sun Y, Ni W, Wang D, Ren J, Zhao D, Yu S, Liu S, Zhang S, Wang S, Wang W, Liu M
Carbohydrate polymers 2025 Sep 1;363:123708
Carbohydrate polymers 2025 Sep 1;363:123708
The role of endoplasmic reticulum stress in BPS-induced disruption of endometrial decidualization.
Xu S, Tan Z, Zhang R, Kang J, Zhang Z, Fu Q, Tao Y, Xiong Y, Zhang Y
Ecotoxicology and environmental safety 2025 Sep 1;302:118737
Ecotoxicology and environmental safety 2025 Sep 1;302:118737
m(6)A-methylated TAL1 exacerbates lipid accumulation in ethylene bisdithiocarbamate metabolite-induced anorectal malformations in rat fetuses via miR-205/LCOR signaling.
Yao Y, Yang S, Bai Y, Yuan Z, Yang Z
Ecotoxicology and environmental safety 2025 Sep 1;302:118594
Ecotoxicology and environmental safety 2025 Sep 1;302:118594
Multi-omics reveals the polyethylene terephthalate carcinogenicity: Cancer progression and immune microenvironment.
Yang K, Zhou X, Wu K, Wu J, Huang C, Yang L
Ecotoxicology and environmental safety 2025 Sep 1;302:118522
Ecotoxicology and environmental safety 2025 Sep 1;302:118522
Aloperine ameliorates radiation enteritis by driving the TAS2R138-PLCβ/GAPDH axis-mediated glucose metabolic reprogramming to inhibit ferroptosis in intestinal epithelial cells.
Zeng X, Pang S, Lu H, Zhu J, Li Z, Liu N, Zhang X, Wang Y, Wei Z
Biochemical pharmacology 2025 Sep 1;242(Pt 1):117292
Biochemical pharmacology 2025 Sep 1;242(Pt 1):117292
Crocin drives intestinal microbiota variation in a rat model of Alzheimer's disease by reducing DKK3 expression.
Yang X, Jiang M, Wu M, Jin X, Wang X, Lv L, Liu L
Brain research 2025 Sep 1;1862:149734
Brain research 2025 Sep 1;1862:149734
LAPTM4B as a key regulator in the copper-induced endoplasmic reticulum-lysosome interplay disorder in duck liver and the protective role of baicalin.
Shang H, Dai X, Chen J, Xing C, Gao X, Cao H, Hu G, Li H, Hu M, Yang F
Journal of animal science and biotechnology 2025 Sep 1;16(1):121
Journal of animal science and biotechnology 2025 Sep 1;16(1):121
Dual inhibitors of butyrylcholinesterase and histone deacetylase 6 for the treatment of Alzheimer's disease: design, synthesis, and biological evaluation.
Lv B, Wang Z, Wang Q, Xu Z, Tang J, Pei Y, Bian Y, Sun H, Chen Y
Bioorganic & medicinal chemistry 2025 Sep 1;127:118219
Bioorganic & medicinal chemistry 2025 Sep 1;127:118219
PADI1 aggravates endoplasmic reticulum stress in trophoblast cells by inhibiting the FAK-ERK signaling pathway.
Ning J, Yang S, Gao F, Wang L, Lin Z, Cheng D, Fan K
Tissue & cell 2025 Oct;96:102976
Tissue & cell 2025 Oct;96:102976
Isoquercitrin mitigates intestinal ischemia-reperfusion injury by regulating intestinal flora and inhibiting NLRP3 inflammasome activation.
Xu H, He TQ, Chen SY, Shi RR, Xu J, Xing YR, Shi D, Liu YQ, He BS, Gu JH
Redox biology 2025 Oct;86:103803
Redox biology 2025 Oct;86:103803
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
Yang R, Zhan Y, Deng Z, Zhang J, Chen S, Zhang Y, Fu H, Meng X, Wu J, Gu Y, Huang Q, Wang C, Xie J
Redox biology 2025 Oct;86:103793
Redox biology 2025 Oct;86:103793
A potential strategy for improving offspring behavior in maternal immune activation: Amantadine-mediated suppression of neuroinflammation.
Wu J, Liu Y, Wang B, Wang Y, Liu B, Tan Y, Cai D, Liu K, Wei D
Animal models and experimental medicine 2025 Oct;8(10):1836-1850
Animal models and experimental medicine 2025 Oct;8(10):1836-1850
YTHDF1 regulates the proliferation and differentiation of keratinocytes via the PI3K/AKT signaling pathway in atopic dermatitis.
Huang M, Dong L, He Y, Cai X, Lu Y, Xu J, Xiao F
Allergology international : official journal of the Japanese Society of Allergology 2025 Oct;74(4):591-604
Allergology international : official journal of the Japanese Society of Allergology 2025 Oct;74(4):591-604
SUR1-TRPM4 Regulates Aquaporin-4 Subcellular Localization by Astrocytic Endfeet Calcium Signals Following Status Epilepticus.
Yang T, Lin Z, Yu M, Li Y, Chen J, Liu Y, Huang K, Pan S
Glia 2025 Oct;73(10):2057-2076
Glia 2025 Oct;73(10):2057-2076
Liver sinusoidal endothelial cells secret C-X-C motif chemokine ligand 10 to promote the recruitment of invariant NKT cells in acetaminophen-induced liver injury.
Wang F, Zhang S, Yao Y, Yu P, Xue K, Xu X, Li G, Zhou H
Science China. Life sciences 2025 Oct;68(10):2982-2994
Science China. Life sciences 2025 Oct;68(10):2982-2994
Identification and Experimental Verification of PDK4 as a Potential Biomarker for Diagnosis and Treatment in Rheumatoid Arthritis.
Zheng X, Huang J, Meng J, Wang H, Chen L, Yao J
Molecular biotechnology 2025 Oct;67(10):3975-3992
Molecular biotechnology 2025 Oct;67(10):3975-3992
Proteomic Analysis Provides a New Sight Into the CRABP1 Expression in the Pathogenesis of Hirschsprung Disease.
Bu L, He L, Wang X, Du G, Wu R, Liu W
Biochemical genetics 2025 Oct;63(5):3989-4003
Biochemical genetics 2025 Oct;63(5):3989-4003
UQCRC1 is a Key Pathogenic Determinant and Potential Therapeutic Target for Cognitive Impairment in Alzheimer's Disease.
Zhang J, Wu Z, Long Z, Feng C, Bai F, Li H
Molecular neurobiology 2025 Oct;62(10):13786-13806
Molecular neurobiology 2025 Oct;62(10):13786-13806
Dual targeting of the Wnt and DNAJB6/MRJ regulatory loop as an anti-RSV strategy.
Lu CY, Lai PY, Huang JM, Chang LY, Yen TY, Tarn WY, Huang LM
Virology 2025 Oct;611:110641
Virology 2025 Oct;611:110641
Exosome miR-6990-5p from MMP14(high) Macrophage Promotes Fibrosis Through Th17 Cell Differentiation in Hypersensitivity Pneumonia.
Peng D, Li J, Qin B, Xiong A, Ran Q, Bai L, He X, Li X, Zhang L, Arooj M, Li G
European journal of immunology 2025 Oct;55(10):e70048
European journal of immunology 2025 Oct;55(10):e70048
TAP1 promotes immune escape by activating JNK/STAT1/PD-L1 signaling in EBV-associated gastric cancer.
Shan W, Li G, Zhang H, Zhang R, Liu J, Gao L, Li Y, Fan L, Yang C, Liu J
Molecular and cellular biochemistry 2025 Oct;480(10):5429-5446
Molecular and cellular biochemistry 2025 Oct;480(10):5429-5446
Nonstructural Protein 1 Mediates HMGB1 Release by Targeting Histone H1.0 After Respiratory Syncytial Virus Infection In Vivo and In Vitro.
Zhou N, Che S, Zhai H, Xie X, Liu E, Xie J
Inflammation 2025 Oct;48(5):3579-3591
Inflammation 2025 Oct;48(5):3579-3591
High level expression of OSBPL11 is associated with atherosclerosis and Alzheimer's disease.
Zhang H, Chen Y, Xu Q, Wu X, He N, Ren Z, Wang G, Tang Z, Xiang Q, Liu L
Inflammation 2025 Oct;48(5):3097-3110
Inflammation 2025 Oct;48(5):3097-3110
OTUD1 downregulates PD-L1 expression by deubiquitinating STAT3 and promotes the immune response in ccRCC.
Liang H, Liu X, Guo W, Xiong W, Ren D, Liu W
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1349-1361
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1349-1361
Targeting miR-144-5p/ACSM1 Axis Alleviates Doxorubicin-Induced Heart Failure by Inhibiting Lipid Peroxidation.
Kao GY, Xu Y, Zhang Y, Xu G
Current medical science 2025 Oct;45(5):1055-1067
Current medical science 2025 Oct;45(5):1055-1067
HOMER3 orchestrates SRC-YAP1 activity that promotes tumor cell growth and antagonizes anti-tumor immunotherapy in prostate cancer.
Tong T, Lei H, Huang M, Yang Z, Dai X, Zou H, Guo Y, Luo J, Teng Q, Cao F, Pang J, Li P
Oncogene 2025 Oct;44(41):3895-3908
Oncogene 2025 Oct;44(41):3895-3908
RCN3 functions as a tumor promoter in colorectal cancer by modulating the GRP78-PI3K-AKT signaling pathway.
Huang M, Qin B, Xie Z, Zhou R, Lin Z, Zhou L, Han Z, Liu S, Zhuang K
Oncogene 2025 Oct;44(40):3850-3863
Oncogene 2025 Oct;44(40):3850-3863
LGI3 promotes the progression of TFE3-rearranged renal cell carcinoma through GEMIN6/AURKB axis.
Liu J, Feng H, Xiong Z, Cao S, Cai T, Wei W, Tao W, Zhang X, Ma X, Li X
Oncogene 2025 Oct;44(39):3729-3740
Oncogene 2025 Oct;44(39):3729-3740
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Yang J, Zhang H, Wang Y, Luo Y, Zheng W, Liu Y, Jiang Q, Deng J, Liu Q, Zhang P, Huang H, Yu C, Xu Z, Chen Y
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Neuroscience bulletin 2025 Oct;41(10):1805-1823
AXL-mediate GEF-H1 phosphorylation was involved in microglia synapse phagocytosis in 5xFAD mice.
Chen G, Zhang J, Dong A, Xiao L, Huang P, Huang T, Ye Q, Huang E
Experimental neurology 2025 Oct;392:115327
Experimental neurology 2025 Oct;392:115327
Engineering a Lipid Nanoparticle with Atypical Calcium Crystal Structure for Enhanced IFNβ-Mediated Immunotherapy.
Luo Y, Zhu C, Guo X, Xie Y, Sun Y, Lu D, Xia Y, Lin Z, You F
Advanced materials (Deerfield Beach, Fla.) 2025 Oct;37(42):e2419870
Advanced materials (Deerfield Beach, Fla.) 2025 Oct;37(42):e2419870
Umbilical cord blood-derived exosomes deliver miR-182-5p to Therapeutically target the MYD88/NF-κB signaling pathway in rat peri-implantitis.
Liu H, Zhu D, Lang L, Liu M, Yang Z, Zhang Z, Shen Z
Materials today. Bio 2025 Oct;34:102246
Materials today. Bio 2025 Oct;34:102246
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Ming P, Li K, Zhu W
Materials today. Bio 2025 Oct;34:102236
Materials today. Bio 2025 Oct;34:102236
Engineered biomimetic vesicles induce cuproptosis and disrupt efferocytosis for metastatic adenoid cystic carcinoma immunotherapy.
Li M, Dong W, Cui Y, Li J, Yang C, Zhang D, Fu X
Materials today. Bio 2025 Oct;34:102233
Materials today. Bio 2025 Oct;34:102233
Analysis of the therapeutic effect and potential mechanism of Fe(3)O(4)-polydopamine nanoparticles in enhancing mesenchymal stem cells therapy for pulmonary fibrosis.
Zhao X, Kong C, Xia X, Zhao K, Hao M, Gao Y, Wang Y, Chen Z, Jiang J
Materials today. Bio 2025 Oct;34:102098
Materials today. Bio 2025 Oct;34:102098
SAMHD1 deficiency disrupts macrophage autophagy-lysosomal homeostasis and promotes inflammation via the mTOR-MITF-CTSD axis in ulcerative colitis.
Yaxian L, Xiaodong W, Futao M, Huizhen W, Chuansheng W, Mengdi M, Bo Y, Yida L, Xin X, Ziqing F, Mingdian L, Yuxian S, Yongxiang L
International journal of biological macromolecules 2025 Oct;327(Pt 1):147188
International journal of biological macromolecules 2025 Oct;327(Pt 1):147188
Mechanism of Banxia Houpo Decoction in Treating Gastroesophageal Reflux Disease: An Integrated Approach of Compound Analysis, Network Pharmacology and Empirical Verification.
Song SZ, Xie JN, Zhang JW, Gong AX
Chinese journal of integrative medicine 2025 Oct;31(10):889-898
Chinese journal of integrative medicine 2025 Oct;31(10):889-898
The long noncoding RNA SNHG12 defines KEAP1 stability and ferroptosis susceptibility by targeting E3 ligase TRIM25.
Guo Y, Zhu S, Wu W, Cai Y, Sehgal SA, Huang F, Wu H
The Journal of biological chemistry 2025 Oct;301(10):110689
The Journal of biological chemistry 2025 Oct;301(10):110689
TSLP mitigates post-infarction myocardial remodeling by promoting eosinophil recruitment and inhibiting JAK1-STAT5-mediated ferroptosis.
Wang Y, Cao C, Fu T, Yu F, Qi J, Liu G, Zhang J
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2269-2286
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2269-2286
Aspirin-Inspired 6-O-Carboxymethyl-N-Acetylglucosamine: A potent antitumor agent with enhanced efficacy.
Qiao Z, Zhang G, Chen X, Zhang Y, Zhang S, Qin X, Sohail A, Xu X, Liu J, Han B, Wang D, Zhang X, Wang Z
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2254-2268
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2254-2268
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Liu K, Huang Y, Xiao W, Liao J, Ouyang S, Liang Y, Fu J
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Scorpion venom heat-resistant synthetic peptide regulates Nrf-2 to alleviate neuronal pyroptosis in an AD model induced by endoplasmic reticulum stress under PM(2.5) exposure.
Duan K, Qin C, Zhang Y, Li D, Zhang J, Li F
Toxicon : official journal of the International Society on Toxinology 2025 Oct;265:108504
Toxicon : official journal of the International Society on Toxinology 2025 Oct;265:108504
Licoisoflavone A inhibits colorectal cancer cell proliferation through targeting CDK2-Cyclin E1 axis-mediated cell cycle transition.
Cui J, Chen H, Chen Y, Zhou B, Huang C, Wang P, Gong P, Fan Z, Wang L
Biochemical pharmacology 2025 Oct;240:117124
Biochemical pharmacology 2025 Oct;240:117124
The exosomal miRNA-3184-3p derived from highly metastatic melanoma cells promotes metastatic competency via the positive feedback loop of NLK/Wnt/S100A11.
Chen Y, Zeng B, Xiang M, Han X, Zhang X, Chen H, Zhao Q, Liu D, Li X, Li J, Zhang Y, Shi L, Li B, Chen Y, Tang Y, Li J, Xing HR, Wang J
Biochemical pharmacology 2025 Oct;240:117086
Biochemical pharmacology 2025 Oct;240:117086
Identification and characterization of a potent peptide inhibitor targeting FOXM1 in cancer therapy.
Liang A, Chang M, Shang Z, Wang S, Huai R, Hua X, Wu D, Xiang K, Qi S, Jia S, Qi H, Jiang Y, Liu X, Mao C
Biochemical pharmacology 2025 Oct;240:117064
Biochemical pharmacology 2025 Oct;240:117064
Gut microbiota derived butyrate enhances ferroptosis sensitivity in endometriosis through FFAR2/PPAR-γ/PINK1/Parkin mediated mitophagy.
Gou Y, Ding J, Wang H, Bai R, Wang H, Wang B, Cao Y, Liu J, Cui J, Zhang Z
Free radical biology & medicine 2025 Oct;238:640-652
Free radical biology & medicine 2025 Oct;238:640-652
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Wang X, Liu T, Fei Y, Zhang S, Yang Y, Chen Z, Zhu R, Deng S, Zhang T, Wu D, Xu Y
Free radical biology & medicine 2025 Oct;238:595-610
Free radical biology & medicine 2025 Oct;238:595-610
Fe(2)O(3) nanoparticles induce ferroptosis by binding to the N-terminus of ACSL4 and suppressing its ubiquitin-mediated degradation.
Wei XL, Yu AG, Zhang X, Pantopoulos K, Liu ZB, Xu PC, Zheng H, Luo Z
Free radical biology & medicine 2025 Oct;238:123-136
Free radical biology & medicine 2025 Oct;238:123-136
Enhancing the encapsulation efficiency, bioavailability, and antioxidant efficacy of quercetin and maize peptide by a novel multi-frequency pulsed ultrasonic-assisted nanoliposomal encapsulation system.
Qu W, Deng X, Guo T, Zhou C, Ma H
Food research international (Ottawa, Ont.) 2025 Oct;218:116874
Food research international (Ottawa, Ont.) 2025 Oct;218:116874
TRIM45 restricts influenza virus infection through modulating the chaperone-mediated autophagic degradation of viral PB2 protein.
Wang Y, Jiang L, Li Q, Li M, Shi W, Wang B, Wang G, Deng G, Shi J, Tian G, Zeng X, Chen H, Li C
PLoS pathogens 2025 Oct;21(10):e1013630
PLoS pathogens 2025 Oct;21(10):e1013630
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation.
Yu T, He Y, Li H, Sun Q, Chen M, Wang W, Li Q, Ju S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115653
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115653
M6A-mediated uc003pes.1 stability regulates proliferation and migration of human coronary artery smooth muscle cells via scaffolding STAT1 and USP10.
Jiang R, Jia Q, Li C, He S, Zhou H, Ren M, Liang L, Jia E
Biochimica et biophysica acta. Molecular cell research 2025 Oct;1872(7):120023
Biochimica et biophysica acta. Molecular cell research 2025 Oct;1872(7):120023
MitoQ for vitiligo by mitigating PARP1 translocation aberrations: Network pharmacology and experimental validation.
Xiong R, Jin S, Li Y, Dong T, Song X, Guan C
Biochimica et biophysica acta. Molecular cell research 2025 Oct;1872(7):119995
Biochimica et biophysica acta. Molecular cell research 2025 Oct;1872(7):119995
LILRB4 exacerbates myocardial ischemia-reperfusion injury by promoting inflammation and pyroptosis.
Yang J, Zhang M, Liu L, Zhang P, Liu H, Yang Z, Chen C, Li R, Zhai Y, Li W, Wang W, Yang J, Huang C, Zhang J
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167959
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167959
Galectin-3 gene deletion alters lipid profile in healthy and cardiomyopathy mouse hearts.
Du XJ, Huynh K, Ziemann M, She G, Wu W, Duong T, Hai XX, Yang YY, Zhao WB, Lu Q, Zhang Y, Deng XL, Meikle PJ
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159676
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159676
Exploring the mechanism of Levistolide A in the treatment of lung cancer cells based on network analysis, molecular docking and experimental validation.
Zhao L, Wang J, Han Y, Wang Q, Yang W, Zhang Y, Lin Z, Zhu L, Piao J
Bioorganic chemistry 2025 Oct;165:109002
Bioorganic chemistry 2025 Oct;165:109002
High-Calorie Diet During Pregnancy Leads to Muscular Fibrosis and Neuromuscular Damage in Offspring Mice.
Son JS, Chae SA, Chun YH, Wang H, Jiang Z, Du M
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70027
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70027
Targeting the Phosphoinositide 3-Kinase/Protein Kinase B Pathway Suppresses Y-Box Binding Protein 1 Expression and Inhibits Colorectal Cancer Progression.
Shan H, Wang Y, Hu S, Wang Y, Qin R, Zhang N, Tian G, Qiu Z
World journal of oncology 2025 Oct;16(5):487-501
World journal of oncology 2025 Oct;16(5):487-501
Ononin, a Natural Isoflavone Glycoside, Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Regulating Neuroinflammation and Oxidative Stress.
Li M, Peng Q, Zhu M, Liu Q, Yang S, Gong C, Lin J, Yu Q
Brain and behavior 2025 Oct;15(10):e70952
Brain and behavior 2025 Oct;15(10):e70952
Huo Po Xia Ling decoction exerts preventive and improvement effects on gastric precancerous lesions by remodeling gut microbiota and associated metabolites.
Song Y, Qiao Y, Gao S, Cao M, Shan Y, Mao J, Chi X, Chang L, Shan B, Huo B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157131
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157131
Columbianadin targets TRIM7 to maintain P2X7 palmitoylation, inhibiting cuproptosis in synovial M2 macrophages.
Li Z, Huang Z, Liao X, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157091
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157091
Selenium alleviates cadmium-induced Golgi stress via HSPB7/GM130/CX-43 axis in the heart of sheep.
Li J, Lin S, Yang F, Dai X, Xin C, Xiong Z, Gao F, Wang Y, Chen J, Cao H
The Journal of nutritional biochemistry 2025 Oct;144:109993
The Journal of nutritional biochemistry 2025 Oct;144:109993
A Novel Injectable Composite Hydrogel HAp-GelMA Co-Doped Magnesium/Zinc Promotes Bone Generation and Angiogenesis Synergistically.
Qiang L, Zhang T, Zhang Q, Yang T, Shan J, Shen G, Kong W, Wei J, Wang J, Liu Y, Niu H, Zheng P
Advanced healthcare materials 2025 Oct;14(27):e01008
Advanced healthcare materials 2025 Oct;14(27):e01008
SIRT1 Expression in Human Gastrointestinal Tumors and Its Clinical Significance.
Liu W, Li X, Deng W
Cancer medicine 2025 Oct;14(19):e71217
Cancer medicine 2025 Oct;14(19):e71217
NSUN2-mediated m5C hypermethylation of hsa_circ_0004516 promotes breast cancer brain metastasis by activating AKT signaling.
Li M, Li J, Wen H, Li J, Wang S, Guo J, Zhang D, Zhang A, Cui C, Fu R, An M, Zhang W, Fu B
Non-coding RNA research 2025 Oct;14:177-190
Non-coding RNA research 2025 Oct;14:177-190
LncRNA MEG3/CTCF-CXCR4 axis functions in the regulation of breast cancer cell migration.
Elhassan G, Bu X, Liu J, Hou S, Yan J, Lei H
Non-coding RNA research 2025 Oct;14:117-128
Non-coding RNA research 2025 Oct;14:117-128
Silibinin attenuates 3-nitropropionic acid-induced ovarian toxicity by alleviating oxidative stress and granulosa cell apoptosis.
Gai Y, Wu W, Wang H, Li Y, Li C, Wang Y, Zhao Y, Hu J, Luan X
Reproductive toxicology (Elmsford, N.Y.) 2025 Oct;137:109027
Reproductive toxicology (Elmsford, N.Y.) 2025 Oct;137:109027
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
He Z, Feng YD, Zhang YX, Gao X, Liu JJ, Liu S, Wu GQ
Cellular signalling 2025 Oct;134:111932
Cellular signalling 2025 Oct;134:111932
Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway.
Miao L, Chen M, Zhou Y, Pan S, Li X, Wang Y, Zhang J, Zhu X
Cellular signalling 2025 Oct;134:111916
Cellular signalling 2025 Oct;134:111916
Tumor suppressor FBXO11 drives ubiquitin proteasomal degradation of KIF2C to limit ovarian cancer progression and is transcriptionally repressed by ZNF217.
Chen Q, Ouyang L
Cellular signalling 2025 Oct;134:111910
Cellular signalling 2025 Oct;134:111910
Curcumin alleviates lipopolysaccharide-induced alveolar epithelial Glycocalyx damage by modulating the Rac1/NF-κB/HPSE pathway.
Xu W, Ou D, Zhao Y, Liu Y, Yan P, Li S, Sun Q, Zhang X, Liu H, Huang J, Fang Y
Cellular signalling 2025 Oct;134:111909
Cellular signalling 2025 Oct;134:111909
IL-6/KIAA1429 promotes ferroptosis resistance in endometrial cancer through m6A modification of DDIT3.
Shen X, Shu W, Zhang J, Zhou T, Dong K, Zhang J, Yao Y, Li H, Cheng S, Zhang T, Chen G, Yu S, Zhang Q, Wang H, Liu Y
Cellular signalling 2025 Oct;134:111906
Cellular signalling 2025 Oct;134:111906
Effects of higenamine on M1/M2 polarization and osteoclast differentiation in rheumatoid arthritis via the THBS-1/TGF-β signaling pathway.
Chen DT, Wan ZJ, Sheng XP, Rao W, Zhan XH, Gu JL, Wei XZ, Fan TY
Cellular signalling 2025 Oct;134:111905
Cellular signalling 2025 Oct;134:111905
Cordycepin promotes the survival of random-pattern skin flaps via autophagy in a rat model.
Chen Y, Zhang W, Lin L, Wang T, Xu Q, Zhou X, Wu Z
Cellular signalling 2025 Oct;134:111890
Cellular signalling 2025 Oct;134:111890
KIF18B drives the malignant progression of gliomas by activating the Notch pathway.
Zhang L, Li F, Zhang L, Zhou Y, Liu Y, Liu J, Cheng Y, Shu J, Zhao H, Wei Y
Cellular signalling 2025 Oct;134:111888
Cellular signalling 2025 Oct;134:111888
EP300-interacting inhibitor of differentiation 3 is required for spermatogenesis in mice.
Zhang P, Zhang L, Yu L, Zhou X, Chen X, Zhou Y, Wang N, Zhu H
Andrology 2025 Oct;13(7):1901-1912
Andrology 2025 Oct;13(7):1901-1912
DEL-1 Protects the Myocardium From Ischemia/Hypoxia Injury Through Regulating the Sirt1/NF-κB Signaling Pathway.
Hu B, Zhang W, Yu WC, Lin H
Immunity, inflammation and disease 2025 Oct;13(10):e70288
Immunity, inflammation and disease 2025 Oct;13(10):e70288
Sonogenetic neuromodulation prevents post-myocardial infarction malignant arrhythmia and cardiac remodeling through the brain-heart circuit.
Hu H, Hu C, Cheng X, Wang J, Guo W, Cheng Y, Jiang H, Wang S
Basic research in cardiology 2025 Oct;120(5):1037-1054
Basic research in cardiology 2025 Oct;120(5):1037-1054
Targeting IGF1R Overcomes Armored and Cold Tumor Microenvironment and Boosts Immune Checkpoint Blockade in Triple-Negative Breast Cancer.
Wan M, Mei J, Cai Y, Zhou J, Xue N, Jiang Y, Zhang Y, Huang J, Zhu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e01341
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e01341
Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis-Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR-433-3p/HMGA2 Axis.
Lin Z, Fu Y, Mao L, Yan H, Liu W, Tang X
Clinical and experimental dental research 2025 Oct;11(5):e70208
Clinical and experimental dental research 2025 Oct;11(5):e70208
EOAI3402143 inhibits lung adenocarcinoma progression through the NF-κB/NR4A1 pathway.
Xu J, Liu W, Chen L, Zhang J, Zhang D, Huang H, Zhang X, Huang X, Zhang G
Acta biochimica et biophysica Sinica 2025 Oct 9;58(4):833-44
Acta biochimica et biophysica Sinica 2025 Oct 9;58(4):833-44
P2RX4 promotes hepatocellular carcinoma progression via calcium-mediated PI3K/AKT activation and immune remodeling.
Wang J, Gu Y, Niu Z, Tang F, Li Y
World journal of surgical oncology 2025 Oct 9;23(1):363
World journal of surgical oncology 2025 Oct 9;23(1):363
Single-cell RNA sequencing reveals that Danggui Buxue Tang decoction facilitates wound healing after anal fistula by promoting M2 macrophage polarization.
Pang X, Wang Y, Guo J
Hereditas 2025 Oct 9;162(1):204
Hereditas 2025 Oct 9;162(1):204
Network Dysfunction Precedes Neurodegeneration in a dox-Regulatable TDP-43 Mouse Model of ALS-FTD.
Rodemer W, Ra I, Gujral J, Jia E, Juul H, Zhang B, Hoxha K, Xing B, Mehta S, Farag M, Rekulak S, Porta S, Jensen FE, Talos DM, Lee VM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Oct 8;45(41)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Oct 8;45(41)
Nanovesicles Synergistically Regulate Ferroptosis Characteristic Macrophage-Induced Angiogenesis via Ferritin Heavy Chain 1/Glutathione Peroxidase 4 Pathway to Promote Peripheral Nerve Regeneration.
Huo N, Xu G, Zhou H, Liu Y, Li S, Yang X, Liu J, Wang W, Yang N, Zhou N
ACS applied materials & interfaces 2025 Oct 8;17(40):55876-55894
ACS applied materials & interfaces 2025 Oct 8;17(40):55876-55894
Fosl2 facilitates chromatin accessibility to determine developmental events during follicular maturation.
Zhang H, Li Z, Zhu Y, Lyu W, Wei W, Wang H, Tian S, Yue W, Zhong J, Sun QY, Guan Y
Nature communications 2025 Oct 8;16(1):8955
Nature communications 2025 Oct 8;16(1):8955
Ferroptosis-Enhanced Radiopharmaceutical Therapy via a Manganese-Based Nanoplatform.
Zhu Z, Yang B, Wang K, Li Y, Zhu K, Gao H, Ma H, Shao F, Li F, An R, Liu N, Zhang W
Molecular pharmaceutics 2025 Oct 6;22(10):6215-6227
Molecular pharmaceutics 2025 Oct 6;22(10):6215-6227
Plin4 modulates lipid droplet accumulation and ferroptosis in neurons exposed to benzo[a]pyrene.
Sun H, Ma Z, Guo X, Chen J, He H, Tong X, Ji T, Ding S, Zhou C, Lyu Y, Tian F, Zheng J
Cell death discovery 2025 Oct 6;11(1):442
Cell death discovery 2025 Oct 6;11(1):442
Development of a potent BET inhibitor for the treatment of renal fibrosis.
Huang J, Zhao N, Li J, Zhu J, Liang G, Chen X, Wang N, Zhu H, Pang N, An C, Xiong X
European journal of medicinal chemistry 2025 Oct 5;295:117822
European journal of medicinal chemistry 2025 Oct 5;295:117822
LncPRESS1 promotes the progression and cisplatin resistance of breast cancer through upregulation of ENO1 and activation of glycolysis.
Ke L, Gao W, Leng Y, Chen J, Chen H, Li S, Zhang Y, Luo L
Cell division 2025 Oct 4;20(1):23
Cell division 2025 Oct 4;20(1):23
Multi-omics and network pharmacology approaches reveal the mechanism of action of KeKe tablet against post-infectious cough.
Su M, Zhang J, Wang S, Chen W, Lai M, Peng L, Liang Y, Feng Y, Zhou H, Qiao W, Sun P
Chinese medicine 2025 Oct 4;20(1):160
Chinese medicine 2025 Oct 4;20(1):160
COL6A1, LAPTM5, and ZFAND2A as Crucial Biomolecules Driving Immunoregulation in Human Nucleus Pulposus Degeneration.
Lu ZY, Chen PB, Xu QY, Mardan M, You MJ, Li B, Jiang SD, Jiang LS, Zheng XF
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71145
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
Shi X, Hao R, Yang Z, Wang X, Lu Y, Wang X, Ji H, Ma S, Liu X, Hu J, Qi Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
Effect of fibrinogen like protein 1 on cisplatin-resistance in laryngeal carcinoma through targeting integrinβ1 in vivo and in vitro.
Li Z, Fang J, Ge H, Wang X, Dong H, Yu H, Liu Y, Li T
Discover oncology 2025 Oct 31;16(1):2000
Discover oncology 2025 Oct 31;16(1):2000
A novel prognostic tool for triple-negative breast cancer: creating and testing a parthanatos-related gene model.
Yang Z, Chen S, Sun J, Wu G, Mu D, Wang J
Translational cancer research 2025 Oct 31;14(10):7018-7036
Translational cancer research 2025 Oct 31;14(10):7018-7036
ANK3 Is Regulated by Recursive Splicing and Inhibits Hepatocellular Carcinoma Metastasis by Inhibiting E-Cadherin Protein Degradation.
Guo Y, Fu X, Tian Y
Frontiers in bioscience (Landmark edition) 2025 Oct 30;30(10):46013
Frontiers in bioscience (Landmark edition) 2025 Oct 30;30(10):46013
Lentinan ameliorates angiotensin II-induced hypertension-associated intestinal barrier injury through inactivation of PSMB8-ATRAP signaling.
Zhao D, Cai Y, Chen B, Pan Y, Chen D, Xie J, Cao Y, Lian F, Yan X
International immunopharmacology 2025 Oct 30;164:115418
International immunopharmacology 2025 Oct 30;164:115418
LncRNA MIR17HG accelerates the development of atherosclerosis by promoting macrophage pyroptosis through the miR-301a-3p/TXNIP pathway.
Wang YP, Liu X, Xu XD, Hui L, Xu GH, Ma MQ, Zhu L, Ren K
International immunopharmacology 2025 Oct 30;164:115407
International immunopharmacology 2025 Oct 30;164:115407
1,8-Cineole alleviates spinal cord injury by inhibiting microglial pyroptosis via the P38 MAPK and PI3K/AKT/NLRP3 signaling pathways to protects neurons.
Zhou W, Liu Z, Qiu X, Tian M, He B, Tang C, Tang Q, Ye R, Zhong D, Liao Y
International immunopharmacology 2025 Oct 30;164:115400
International immunopharmacology 2025 Oct 30;164:115400
Anemoside B4 improves cardiac function after myocardial infarction by regulating HTR2A/ERK pathway.
Lv M, Sun Q, Yu Y, Yu D
International immunopharmacology 2025 Oct 30;164:115394
International immunopharmacology 2025 Oct 30;164:115394
Oridonin alleviates SiNPs-induced pulmonary fibrosis by inhibiting pyroptosis via IRE1α-XBP1s-NLRP3 pathway.
Ban J, Peng X, Zhang Y, Liu Y, Wei Y, Ao L, Tian H, He X, Zhao H, Li J
International immunopharmacology 2025 Oct 30;164:115388
International immunopharmacology 2025 Oct 30;164:115388
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
Tsopmejio ISN, Tang S, Gao XF, Liu Z, Li XD, Qi MH, Zhu HY, Wang Z, Li W
International immunopharmacology 2025 Oct 30;164:115378
International immunopharmacology 2025 Oct 30;164:115378
Neuronal pentraxin 1 accelerates post-stroke atherosclerosis by inducing endothelial cell senescence.
Wu Y, Luo R, Guan H, Zhang X, Yang X, Wang W, Li Q
International immunopharmacology 2025 Oct 30;164:115363
International immunopharmacology 2025 Oct 30;164:115363
Effects of Nutritional Disturbances on the Structure and Function of Mitochondria, Oxidative Stress Level, and Fat Deposition in Chicken Liver Cells.
Zhu S, Zhang P, Xing Y, Zhou X, Ge J, Jia X, Gao Y, Geng T
Animals : an open access journal from MDPI 2025 Oct 30;15(21)
Animals : an open access journal from MDPI 2025 Oct 30;15(21)
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
Wu Y, Zhu Y, Jiang R, Gu W, Lu L, Yao N, Du B, Lai J
Cancer cell international 2025 Oct 3;25(1):333
Cancer cell international 2025 Oct 3;25(1):333
Dietary quercetin supplementation alleviates claw lesions in dairy cows by modulating the PI3K/Akt and NF-κB signaling pathways.
Zhai C, Lin J, Yang X, Mu J, Lei L, Wu W, Zheng Y, Shi M, Ma C, Peng H, Li G, Ding J
BMC veterinary research 2025 Oct 29;21(1):636
BMC veterinary research 2025 Oct 29;21(1):636
Med20 regulates myelination in the peripheral nervous system by modulating ferroptosis of Schwann cells.
Yang W, Chen X, Yang C, Mao Y, Zhuang W, Xiao Y, Zhang X, Ou Z, Chen Y
Cell reports 2025 Oct 28;44(10):116448
Cell reports 2025 Oct 28;44(10):116448
STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma.
Wang H, Xiao T, Zhuang H, Liu Y, Jin K, Li J, Li J, Gao Y, Yue D, Cui W, Xu Q, Pan J, Liu K, Wang Y, Chen R, Li H
Cell reports 2025 Oct 28;44(10):116429
Cell reports 2025 Oct 28;44(10):116429
Combination of B-AP15 and HSP90 inhibitor tanespimycin induces ROS-mediated cytotoxicity in human lung cancer cells.
Fu W, Lu H, Yan Y, Shu C, Xu C, Chen Y, Xia Y, Chen J, Chen Y, Zou P, Cui R, Ni D
BMC pharmacology & toxicology 2025 Oct 28;26(1):177
BMC pharmacology & toxicology 2025 Oct 28;26(1):177
Macrophage-derived exosomes carrying miR-30a-5p alleviates IL-13/IL4-induced epithelial-mesenchymal transition in mouse bronchial epithelial cells via Runx1.
Wu B, Li D, Wang Y, Xu J, Li L, Wang M
BMC pulmonary medicine 2025 Oct 28;25(1):496
BMC pulmonary medicine 2025 Oct 28;25(1):496
Villin like suppresses nasopharyngeal carcinoma proliferation by downregulating MYC.
Wen Y, Zhou Z, Zhou Y, Huang Z
Scientific reports 2025 Oct 28;15(1):37628
Scientific reports 2025 Oct 28;15(1):37628
Dysregulated autophagy, neural signaling pathways and gut-brain axis in a novel vestibular migraine-like rat model: implications for pathogenesis.
Huang Y, Li H, Chen Q, Yu Q, Zhang C, Shi S, Ren Y, Sun T, Zhai Q, Ban J, Ying C, Pan Y
The journal of headache and pain 2025 Oct 27;26(1):231
The journal of headache and pain 2025 Oct 27;26(1):231
Human induced pluripotent stem cell-derived cardiomyocytes improve recovery from myocardial infarction in non-human primates.
Guan X, Zhang P, Wang Q, Zhang Y, Zhang Y, Zhang H, Zhang H, Jiang W, Wu Y, Wang X, Wang D, Wang J, Gao L
Stem cell research & therapy 2025 Oct 27;16(1):581
Stem cell research & therapy 2025 Oct 27;16(1):581
Genotype and phenotype correlation analysis in 27 families with multiple osteochondroma and validation by ATDC5 chondrocyte models.
Guo X, Lin M, Xu S, Liu B, Zhang R, Liu S, Pan Y
Bone & joint research 2025 Oct 27;14(10):901-914
Bone & joint research 2025 Oct 27;14(10):901-914
Mitochondria-associated endoplasmic reticulum membrane (MAM)-associated calpains system in preeclampsia.
Zhang C, Jiang J, Kong H, Ma X, Xin H
BMC pregnancy and childbirth 2025 Oct 25;25(1):1133
BMC pregnancy and childbirth 2025 Oct 25;25(1):1133
Endoplasmic reticulum-resident protein DNAJC10 inhibits glioblastoma metastasis by suppressing XBP-1s-driven EGFR transcription.
Zhao E, Yu Y, Gao Y, Li T, Hao S, Chen M, Xu M, Arjun S, Yang C, Yin Y, Li M
Molecular biomedicine 2025 Oct 24;6(1):84
Molecular biomedicine 2025 Oct 24;6(1):84
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
Zhao W, Wang H, Peng S, Wei Q, Zhang L, Li Y, Yang W
Chinese medicine 2025 Oct 23;20(1):178
Chinese medicine 2025 Oct 23;20(1):178
α-Ketoglutarate Ameliorates Sarcopenia in D-Galactose-Induced Aging Mice by Modulating Protein Homeostasis and Optimizing Mitochondrial Function.
Zhang Y, Wang H, Zhang Y, Wang X, Qiao Z, Wang J, Li Y, Sun Y
Nutrients 2025 Oct 23;17(21)
Nutrients 2025 Oct 23;17(21)
IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders.
McDougal MB, Boys IN, De Maria AM, Nakahara E, Schoggins JW
eLife 2025 Oct 22;13
eLife 2025 Oct 22;13
Molecules interacting with CasL-Like 2 enhances tumor angiogenesis and progression by activating mTOR/HIF1α/VEGF pathway in kidney renal clear cell carcinoma.
Song Y, Zhang J, Liu G, Jiang X, Sun N, He H, Song S, Wang W
Scientific reports 2025 Oct 21;15(1):36581
Scientific reports 2025 Oct 21;15(1):36581
Efficient genetic perturbation of murine sensory neurons in vivo using CRISPR/Cas9.
García G, Shapiro JB, Campbell ZT
bioRxiv : the preprint server for biology 2025 Oct 21;
bioRxiv : the preprint server for biology 2025 Oct 21;
Paeonol reduces IL-1β induced apoptosis and degeneration by regulating MAPK pathway in nucleus pulposus cells.
Yu C, Wei X, Wang J, Wang L, Wang J
Biochemical and biophysical research communications 2025 Oct 20;785:152687
Biochemical and biophysical research communications 2025 Oct 20;785:152687
Single-cell and bulk transcriptomic analyses reveal ITGA5-driven epithelial-mesenchymal transition and metabolic adaptation in thyroid cancer.
Li X, Zhang Y, Pei F, Zhang L
Biochemical and biophysical research communications 2025 Oct 20;785:152678
Biochemical and biophysical research communications 2025 Oct 20;785:152678
KAZN methylation as a potential diagnostic and prognostic marker in non-small cell lung cancer.
Zhu S, He Y, Wang W, Jiao Y, Xu Z, You S, Yu C, Ao J, Long M, Ren J, Zhang H, Liu SL, Bao H, Wang S
iScience 2025 Oct 17;28(10):113585
iScience 2025 Oct 17;28(10):113585
Targeting PURPL RNA enabled rejuvenation of senescence cells via epigenetic reprogramming.
Wang J, Yang X, Su X, Yi W, Sun W, Wei J, Ning YQ, Yan J
Journal of translational medicine 2025 Oct 17;23(1):1127
Journal of translational medicine 2025 Oct 17;23(1):1127
A Cell-Potent Bisubstrate Inhibitor to Probe NatD Acetyltransferase Activity.
Ho YH, Seipp EK, Larndate T, Huang R
ACS chemical biology 2025 Oct 17;20(10):2512-2520
ACS chemical biology 2025 Oct 17;20(10):2512-2520
The CCL20-integrin α5β1 interaction enhances TGF-β/Smad signaling to promote fibroblast activation in pulmonary fibrosis.
Liu S, Wang Q, Min J, Zhang Z, Zhang Y, Yang J, Tan Y, Tan L, Yin M, Zhang Y, Tang X, Peng H, Xia Z, Xiao Y, Zhou Z, Li X, Liu S
Nature communications 2025 Oct 16;16(1):9183
Nature communications 2025 Oct 16;16(1):9183
Whole-transcriptome sequencing analysis of spinal neuronal ferroptosis in aggravating neuropathic pain.
Gao X, Liang X, Gao L, Zhang Y, Zhang L, Jia S, Zhang B, Meng C
Life sciences 2025 Oct 15;379:123882
Life sciences 2025 Oct 15;379:123882
Endoplasmic reticulum stress and autophagy as potential therapeutic targets in SERPINF1 mutation-induced type VI osteogenesis imperfecta.
Tian Y, Chen X, Wei S, Wu W, Liu L, Shi Y, Wu H, Li Z, Jiang J, Zhao W, Wang Y, Li T, Yao Y, Zhao J, Xu C
Life sciences 2025 Oct 15;379:123862
Life sciences 2025 Oct 15;379:123862
Simultaneously induce apoptosis and inhibiting metastasis of Triple negative breast cancer Enabled by a highly potent NIR fluorescent inhibitor.
Zhao Q, Wu J, Yao J, Liu Z, Li C, Sun Q
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Oct 15;339:126183
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Oct 15;339:126183
Bisphenol S as an emerging osteotoxicant: Mechanistic insights from osteoblasts and zebrafish models.
Shi X, Xie H, Liu C, Wu K, Huang W
Ecotoxicology and environmental safety 2025 Oct 15;305:119240
Ecotoxicology and environmental safety 2025 Oct 15;305:119240
Changes of N(6)-methyladenosine modification and unfolded protein response in renal cell injury induced by cadmium.
Wang N, Dai J, Li R, Li W, Liu D, Liu X, Mei Z, Lu H, He Z, Gu S
Ecotoxicology and environmental safety 2025 Oct 15;305:119228
Ecotoxicology and environmental safety 2025 Oct 15;305:119228
Targeted inhibition of MLKL-mediated necroptosis attenuates chronic arsenite exposure-induced lung injury.
Liu Y, Chen Y, Zhang M, Shi Y, Cui Y, Zhang X, Li L, Zhao X, Yang P, Chen J
Ecotoxicology and environmental safety 2025 Oct 15;305:119216
Ecotoxicology and environmental safety 2025 Oct 15;305:119216
Discovery of degrader for FLT3, GSPT1 and IKZF1/3 proteins merging PROTAC and molecular glue targeting FLT3-ITD mutant acute myeloid leukemia.
Yang Y, Yao Q, Song D, Tang K, Tang Z, Hu M, Luo Y, Xie Y
European journal of medicinal chemistry 2025 Oct 15;296:117893
European journal of medicinal chemistry 2025 Oct 15;296:117893
Functional metabolomics revealed pyroglutamic acid may play a key role in idiopathic pulmonary fibrosis.
Wen Y, Nie JH, Qin XM, Li ZY
Journal of pharmaceutical and biomedical analysis 2025 Oct 15;264:116967
Journal of pharmaceutical and biomedical analysis 2025 Oct 15;264:116967
Ursolic acid improves cognitive impairment in type 2 diabetic mice by preventing complement 3 secretion and neuropathy.
Suo Y, Fu Y, Wang C, Wu Y, Tian P
Brain research bulletin 2025 Oct 15;231:111562
Brain research bulletin 2025 Oct 15;231:111562
Effects of wild-type and mutant TDP-43 on cognitive function and hippocampal neurons in mice.
He P, Li Y, Zhou X, Liu T, Huang N, Luo Y
Brain research 2025 Oct 15;1865:149815
Brain research 2025 Oct 15;1865:149815
Nephroprotective mechanism of Kunkui Baoshen decoction in diabetic kidney disease: Targeting the HERC2/NCOA4-mediated autophagy-dependent ferroptosis pathway.
Song SY, Shan CC, Zhou PP, Xu WL, Tan Y, Zhou XQ, Huang LJ, Yan QH, Yu JY
World journal of diabetes 2025 Oct 15;16(10):109568
World journal of diabetes 2025 Oct 15;16(10):109568
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence.
Fang L, Lyu L, Zhong H, Lin J, Ren P, Wang Y, Yin Y, Zhang M, Qu Y
European journal of pharmacology 2025 Oct 15;1005:178043
European journal of pharmacology 2025 Oct 15;1005:178043
Aβ-damaged neural stem cells migration and differentiation through Wnt3a/β-catenin pathway: Protective effects of 17β-E2.
Yang Y, Zhang L, Zhao Y, Chen Z, Wang P, Yang Z
Neuroscience letters 2025 Oct 14;865:138350
Neuroscience letters 2025 Oct 14;865:138350
IL-1β(+) tumor-associated macrophages accelerate glioblastoma progression by amplifying the PGE2-EP4 signaling.
Liang H, Yang Q, Zhong B, Li D, Wu F, Zhang J, Guo C, Zhu Z, Feng M, Zhang Y, Peng H
Journal of neuroinflammation 2025 Oct 14;22(1):233
Journal of neuroinflammation 2025 Oct 14;22(1):233
The Effects and Mechanisms of Ti-Fu-Kang Decoction in Alleviating Central Fatigue: Insights from Network Pharmacology and Metabolomics.
Zhang Y, Zhang Z, Yu Q, Shi Q, Lan B, Liu Y, Zhang W, Li F
Pharmaceuticals (Basel, Switzerland) 2025 Oct 14;18(10)
Pharmaceuticals (Basel, Switzerland) 2025 Oct 14;18(10)
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
Zhang S, Liu Y, Wang M, Ponikwicka-Tyszko D, Wolczynski S, Chen L, Huang X, Yao B, Rahman NA, Li X
Biology of reproduction 2025 Oct 14;113(4):856-869
Biology of reproduction 2025 Oct 14;113(4):856-869
Lysosome stress response and mitochondria injury are the earliest detectable alteration in FSGS.
Dahlke E, Promnitz J, Miranda MT, Saudenova M, Mollet G, Theilig F
Scientific reports 2025 Oct 13;15(1):35570
Scientific reports 2025 Oct 13;15(1):35570
Salvigenin inhibits gastric cancer progression by suppressing the EGFR/PI3K/AKT pathway.
Qiao K, Yang Z, Fang Y, Fang C
Biochemical and biophysical research communications 2025 Oct 10;784:152645
Biochemical and biophysical research communications 2025 Oct 10;784:152645
Blockade of TGF-β1/Smad3 signaling pathway by Bovine Milk-derived extracellular vesicles ameliorates skin fibrosis in systemic sclerosis mice.
Chi J, Li X, Zhu Z, Yang L, Luo C, Chen X, Yuan L, Lu Y, Wang W, Liang C
Biochemical and biophysical research communications 2025 Oct 10;784:152579
Biochemical and biophysical research communications 2025 Oct 10;784:152579
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Wu C, Zhou Y, Mu Y, Cheng Y, Xu W, Huang M, Xu J, Li M, Gu J, Meng X, Qian D
Cancer cell international 2025 Oct 10;25(1):348
Cancer cell international 2025 Oct 10;25(1):348
Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repair.
Liu Y, Wang D, Zheng W, Wang Y, Wang P, Zhao Y, Liu X, Shi Y, Wang Y, Zhou N, González FE, Sun H, Zhou D, Xu X
Journal of nanobiotechnology 2025 Oct 10;23(1):649
Journal of nanobiotechnology 2025 Oct 10;23(1):649
S100A9 inhibition ameliorates HFpEF by modulating mitochondrial fission and oxidative stress.
Wang M, Ren B, Wu X, Guo J, Cao Y, Men L, Shi W, Zhang C, Lin L, Lv J, Li S, Huo S
International immunopharmacology 2025 Oct 10;163:115280
International immunopharmacology 2025 Oct 10;163:115280
Knockdown of Nr4a3 mitigates acute pancreatitis-induced injury by modulating Btg2 to reduce oxidative stress, mitochondrial damage, and apoptosis.
Zhu Z, Dou X, Chen Q, Lu Y
International immunopharmacology 2025 Oct 10;163:115269
International immunopharmacology 2025 Oct 10;163:115269
Bta-miR-199a-3p in embryonic bovine lung cells-derived extracellular vesicles enhances pro-inflammatory cytokine expression in macrophages via DUSP5 upregulation during Mycoplasma bovis infection.
He J, Guo Y, Wang Y, Zhao G
International immunopharmacology 2025 Oct 10;163:115252
International immunopharmacology 2025 Oct 10;163:115252
Vilazodone ameliorates senescence-related Alzheimer's disease like symptoms by targeting Plau to induce autophagy in senescent cells.
Sun W, Sheng X, Li R, Li P, Lin H, Gong Y
International immunopharmacology 2025 Oct 10;163:115251
International immunopharmacology 2025 Oct 10;163:115251
Corilagin alleviates radiation enteritis through caspase-1/gasdermin D-dependent pyroptosis by targeting aldo-keto reductase family 1 member C2 via glutathione metabolism.
Zhang SH, Zhang T, Wang XB, Yang YY, Chen ZX, Liu T, Deng SH, Liu YB, He X, Wu DM, Xu Y
International immunopharmacology 2025 Oct 10;163:115245
International immunopharmacology 2025 Oct 10;163:115245
Tangeretin protects the kidney from ischemia-reperfusion injury by inhibiting inflammatory response through downregulation of MAOA.
Gao J, Liu X, Huang J, Bi X, Hu Y, Chen T, Sun Q, Fang W, Xiao Y
International immunopharmacology 2025 Oct 10;163:115242
International immunopharmacology 2025 Oct 10;163:115242
Monoclonal antibody SZ168 targeting Podoplanin alleviates neuroinflammation by suppressing microglial Pyroptosis in cerebral Hemorrhage.
Liu S, Cui J, Liang R, Wang X, Zhao Y
International immunopharmacology 2025 Oct 10;163:115201
International immunopharmacology 2025 Oct 10;163:115201
Cannabinoid CB1 receptor in dopaminergic circuit from ventral tegmental area to nucleus accumbens links trait anxiety with reward learning.
Cui C, Luo G, Lei J, Shi Y, Yao Y, Ren K, Yang J, Li T, Li M, Peng X, Yang X, Du J, Chen S, Tian B, Zhang P
Translational psychiatry 2025 Oct 10;15(1):395
Translational psychiatry 2025 Oct 10;15(1):395
Dysregulated Protein s-Nitrosylation Promotes Nitrosative Stress and Disease Progression in Heart Failure With Preserved Ejection Fraction.
Li Z, LaPenna KB, Gehred ND, Yu X, Tang WHW, Doiron JE, Xia H, Chen J, Driver IH, Sachse FB, Muraoka N, Katsouda A, Zampas P, Haydel AG, Quiriarte H, Allerton TD, Zagouras A, Wilcox J, Gromova T, Zheng Y, Papapetropoulos A, Shah SJ, Goodchild TT, Jensen MB, Sharp TE 3rd, Vondriska TM, Lefer DJ
Circulation research 2025 Oct 10;137(9):1185-1206
Circulation research 2025 Oct 10;137(9):1185-1206
Albiflorin attenuates post-myocardial infarction cardiac fibrosis through inhibiting the RAS-ERK/MAPK signaling pathway.
Lv M, Yu Y, Niu H, Yu D
Biochemical and biophysical research communications 2025 Oct 1;783:152644
Biochemical and biophysical research communications 2025 Oct 1;783:152644
Andrographolide attenuates oxidative stress and apoptosis in osteoporosis rats via MEK/ERK and Beclin-1/ATG-5-mediated autophagy pathway.
Li Y, Li G, Luo R, Li B
The Journal of pharmacy and pharmacology 2025 Oct 1;77(10):1426-1438
The Journal of pharmacy and pharmacology 2025 Oct 1;77(10):1426-1438
Fusarium solani Activates PANoptosis and Modulates Immune Response in Fungal Keratitis.
Sha X, Yu G, Wu C, Teng X, Xiong X, Fan X, Liu L, Zhong J
Investigative ophthalmology & visual science 2025 Oct 1;66(13):27
Investigative ophthalmology & visual science 2025 Oct 1;66(13):27
PARP1 promoter hypermethylation promotes arsenic-induced skin damage by driving telomere dysfunction-mediated keratinocyte senescence.
Yang L, Wang W, Zhang A
Ecotoxicology and environmental safety 2025 Oct 1;304:119108
Ecotoxicology and environmental safety 2025 Oct 1;304:119108
ATF3 as a molecular nexus linking ferroptosis regulation to sarcopenia pathogenesis via PI3K/Akt pathway activation.
Chen Z, Hu D, Wu C, Wu Z, Lin J, Liu W
Experimental gerontology 2025 Oct 1;209:112830
Experimental gerontology 2025 Oct 1;209:112830
Crinis Carbonisatus-Derived Carbon Dot Suspension Alleviates Temporal Lobe Epilepsy.
Huang Y, Li M, Dong L, He C, Zou P, Xia M, Jin B, Wang S, Lu Z, Qu H, Zhang Y, Kong H
Pharmaceuticals (Basel, Switzerland) 2025 Oct 1;18(10)
Pharmaceuticals (Basel, Switzerland) 2025 Oct 1;18(10)
METTL3-mediated m6A modification promotes ferroptosis in adenomyosis through GPX4 in a YTHDF1-dependent manner.
Tang Y, Li Z, Zhao X, Niu X, Ning S, Liu L, Liu Z, Zhang J, Zhao Q, Han L
Reproduction (Cambridge, England) 2025 Oct 1;170(4)
Reproduction (Cambridge, England) 2025 Oct 1;170(4)
LncRNA MEG3 Regulates Glaesserella parasuis-Induced Apoptosis of Porcine Alveolar Macrophages via Regulating ssc-miR-135/CASP8 Axis.
Jia Y, Qian M, Sun X, Yin R, Li N, Shen A, Wang H, Zeng F, Zhou Y, Yin R
Microorganisms 2025 Oct 1;13(10)
Microorganisms 2025 Oct 1;13(10)
A Pan-Enterovirus Natural Product Inhibitor Targeting a Unique Allosteric Site on the Viral 3C Protease.
Sun S, Wang Q, Zhu M, Zhang X, Zhang X, Yang B
Advanced biology 2025 Nov;9(11):e00845
Advanced biology 2025 Nov;9(11):e00845
Novel SPTB Variations Cause Hereditary Spherocytosis With Cholangiolithiasis and Severe Intrahepatic Cholestasis.
Li LL, Ali S, Bin Q
Annals of human genetics 2025 Nov;89(6):450-458
Annals of human genetics 2025 Nov;89(6):450-458
Targeting CLK1/SRSF7 axis-dependent alternative splicing sensitizes pancreatic ductal adenocarcinoma to chemotherapy and immunotherapy.
Zhang C, Chen Y, Zhu S, Wang Z, Lin H, Lu J, Zhang H, Weng Y, Huang X, Li G, Wu Y, Li Z, Hu J, Xie C, Lai J, Tian Y, Liao C, Chen S
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Nov;83:101292
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Nov;83:101292
Machine learning analysis facilitates the identification of liver biomarkers in postmortem diagnosis of heat stroke.
Pan M, Liu H, Ma C, Dong Y, Dong H
Legal medicine (Tokyo, Japan) 2025 Nov;79:102739
Legal medicine (Tokyo, Japan) 2025 Nov;79:102739
NNMT enhances invasive and migratory capacity of keloid fibroblasts and M2 macrophage polarization.
Yan C, Dong H, Li Z, Cheng X, Wang X
Archives of biochemistry and biophysics 2025 Nov;773:110593
Archives of biochemistry and biophysics 2025 Nov;773:110593
Oncogenic Role of PTPN14 in Pancreatic Cancer Through β-Catenin/NF-κB Pathway Activation.
Luo D, Luo X, Qian S, Liu J
IUBMB life 2025 Nov;77(11):e70078
IUBMB life 2025 Nov;77(11):e70078
Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway.
Liang C, Liu X, Yu J, Shi L, Wei W, Zhu Y, Feng M, Tang T, Li D, Yang T, Zheng J, Ma B, Wei L
Journal of advanced research 2025 Nov;77:669-688
Journal of advanced research 2025 Nov;77:669-688
ATF4 transcriptionally activates NUPR1 to promote ferroptosis in chondrocytes and osteoarthritis development.
Kuang C, Liao T, Jie L, Wei Y, Liu D, Hu E, Ding L, Wang P
The journal of physiological sciences : JPS 2025 Nov;75(3):100039
The journal of physiological sciences : JPS 2025 Nov;75(3):100039
Counteracting lysosome defects alleviates the cellular senescence of Hutchinson-Gilford progeria syndrome.
Wang X, Song Y, Jia M, Zhao G, Liu Y, Xin G, Zhang B, Jiang Q, Zhang C
Science China. Life sciences 2025 Nov;68(11):3329-3339
Science China. Life sciences 2025 Nov;68(11):3329-3339
TRAF6 Exerts Tumor-Promoting Effects via Genetic and Autophagic Modulation in Gastric Cancer.
Zou Y, Mao Z, Xu J, Wang W, Wang Z, Dai J, Zheng R, Du M, Zhang Z
Molecular carcinogenesis 2025 Nov;64(11):1860-1871
Molecular carcinogenesis 2025 Nov;64(11):1860-1871
Integrated transcriptome and single-cell RNA sequencing analysis revealed the prognostic significance of GBP4 in pancreatic adenocarcinoma.
Chi Q, Liang F, Zhang Y, Chen C, Chen X, Pan Y, Weng S
Translational oncology 2025 Nov;61:102532
Translational oncology 2025 Nov;61:102532
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Ju J, Wang C, Nie F, Tian H, Yin Q, Liu J, Wang S, Yang P, Du Y
International endodontic journal 2025 Nov;58(11):1725-1737
International endodontic journal 2025 Nov;58(11):1725-1737
Modeling Lipopolysaccharide-Elicited Inflammation Using 3D Mouse Gastric Organoids.
Xu A, Wang X, Ye Z, Li T, Yang F, Mullen M, Ding X, Liu X, Wang Z
Cell biology international 2025 Nov;49(11):1454-1463
Cell biology international 2025 Nov;49(11):1454-1463
METTL16 promotes progression of clear cell renal cell carcinoma via up-regulating N6-methyladenosine modification of KLK4 mRNA.
Fan B, Niu Y, Li T, Chen H, Zeng K, Li S, Ma Y
Molecular and cellular biochemistry 2025 Nov;480(11):5741-5751
Molecular and cellular biochemistry 2025 Nov;480(11):5741-5751
Dysregulation of immune checkpoint LAG3 in mice exposed to silica.
Duan M, Zhao Y, Qu Y, Hao C, Yao W
Toxicology letters 2025 Nov;413:111729
Toxicology letters 2025 Nov;413:111729
Pinocembrin ameliorates non-alcoholic fatty liver disease by activating Nrf2/HO-1 and inhibiting the NF-κB signaling pathway.
Chen W, Xue D, Feng X, Zhong Y, Li Q, Zhang W, Jiang G
Histology and histopathology 2025 Nov;40(11):1817-1828
Histology and histopathology 2025 Nov;40(11):1817-1828
Astragaloside IV Alleviates Cisplatin Chemotherapy-Induced Nephrotoxicity via Modulation of Nrf2/HO-1/NF-κB Pathway and Reversal of EMT Process.
Ding X, Han X, Zhang Y, Zhang Y, Li F, Wang J
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70565
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70565
Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.
Luo YM, Dong L, Li YL, Lin M, Xie DY, Gao JM, Zhang YD, Zhu YZ, Gong QH
Phytotherapy research : PTR 2025 Nov;39(11):5159-5173
Phytotherapy research : PTR 2025 Nov;39(11):5159-5173
Salvianolic Acid A Mitigates Osteoporotic Bone Loss by Repressing Reactive Oxygen Species via the Nrf2-HO-1 Pathway.
Qiu H, Cai C, Zhang Y, Yang S, Hu X, Chu T
Phytotherapy research : PTR 2025 Nov;39(11):4977-4990
Phytotherapy research : PTR 2025 Nov;39(11):4977-4990
Bone morphogenetic protein 1 as a macromolecular pan-cancer biomarker modulating the immune microenvironment and malignant phenotypes in glioblastoma.
Yu Z, Hu F, Nie C, Fang X, Shen Y, Shang R, Liu H, Zhou Q, Zhang H, Gao A, Liang H
International journal of biological macromolecules 2025 Nov;331(Pt 1):148136
International journal of biological macromolecules 2025 Nov;331(Pt 1):148136
Structural characteristics of a fructan-type polysaccharide from Asparagus cochinchinensis rhizome and its anti-osteosarcoma activity mediated via macrophage polarization.
Xia Y, Zong W, Lan H, Yang J, Feng H, Zhao G, Bao Y
International journal of biological macromolecules 2025 Nov;330(Pt 3):148198
International journal of biological macromolecules 2025 Nov;330(Pt 3):148198
RIPK4-p53 interaction drives aflatoxin B1-induced renal mitochondrial apoptosis via Ser15 phosphorylation: A CRISPR-Cas9 mechanistic study.
Ma Y, Zhao Q, Yuan J, Wang D, Chen X, Yu Y, Li J, Yu M, Yuan J, Lou J, Du S, Wen Y, Wang Y, Wu R, Yan QG, Huang X, Zheng Y, Zhao F, Cao SJ
International journal of biological macromolecules 2025 Nov;330(Pt 3):148130
International journal of biological macromolecules 2025 Nov;330(Pt 3):148130
Myosin heavy chain 9 is a critical host factor for Japanese encephalitis virus entry and replication in U251 cells.
Xu K, Xu YK, Zhan JF, Yuan L, Feng YL, Huang R, Chang YF, Zhu Z, Yang XY, Deng LY, Deng Y, Ren Y, Zhao YH, Zhou XR, Yang J
Veterinary microbiology 2025 Nov;310:110723
Veterinary microbiology 2025 Nov;310:110723
Phase separation of CgSCE3 is required for heat stress resistance and pathogenicity of Colletotrichum gloeosporioides.
Zhao Z, Xie Q, Zhang Y, Luo H, An B, Wang Q
Microbiological research 2025 Nov;300:128289
Microbiological research 2025 Nov;300:128289
FBXL16 regulates TAMs recruitment by mediating cytokine release in gliomas.
Fang Z, Li J, Xiong Y, Luo P, Lu Q, Wu M, Huang K, Zhang L, Zhu X, Wu L
Cancer genetics 2025 Nov;298-299:285-294
Cancer genetics 2025 Nov;298-299:285-294
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
Zhang J, Xu Y, Han X, Gao Y, Wei Z, Sun X
Cancer genetics 2025 Nov;298-299:141-150
Cancer genetics 2025 Nov;298-299:141-150
Dietary BCAA supplementation counteracts the beneficial effects of long-term aerobic exercise against obesity and associated metabolic disorders by suppressing FGF21 expression.
Zhang J, Zhang X, Li P, Liu Y, Zhang C, Lu M, Gao L, Song Z, Sun H, Qiu J
Diabetes, obesity & metabolism 2025 Nov;27(11):6449-6459
Diabetes, obesity & metabolism 2025 Nov;27(11):6449-6459
Network toxicology and cell experiments reveal the mechanism of saikochromone A-induced hepatotoxicity.
Zhang Y, Li F, Ji X, Shao L, Lyu Q, Shao Q
Toxicon : official journal of the International Society on Toxinology 2025 Nov;267:108588
Toxicon : official journal of the International Society on Toxinology 2025 Nov;267:108588
Lysyl oxidase-like 2 inhibition alleviates subretinal fibrosis in neovascular age-related macular degeneration model.
Yang X, Ma A, Liu Y, He Z, Yu J, Su S, Chen J, Sang A
Experimental eye research 2025 Nov;260:110588
Experimental eye research 2025 Nov;260:110588
Mogroside V restores glycolytic function via LDHA promoter demethylation independent of alternative splicing in PCOS granulosa cells.
Li S, Wu J, Lu R, Zhou B, Dai H, Zhang Z, Yang X, Liang X
The Journal of steroid biochemistry and molecular biology 2025 Nov;254:106839
The Journal of steroid biochemistry and molecular biology 2025 Nov;254:106839
E3 ligase SINAT5 mediates ERF113 stability and negatively governs the module of ABI5-like-ERF113 in regulating banana fruit ripening.
Song Z, Li W, Chen H, Shi J, Zhu H, Chen W, Lu W, Li X, Zhu X
The New phytologist 2025 Nov;248(3):1284-1303
The New phytologist 2025 Nov;248(3):1284-1303
MiR-126-5p Derived From Bone Marrow Mesenchymal Stem Cell Exosomes Promotes Skeletal Muscle Regeneration by Regulating FBXO32/MyoD Signaling.
Yan Y, Zheng M, Wang X, Fu T, Qi J, Wei X, Sun Y, Lu J, Luo X, Wang Y, Wang H
Acta physiologica (Oxford, England) 2025 Nov;241(11):e70114
Acta physiologica (Oxford, England) 2025 Nov;241(11):e70114
SETDB2 participates in iron metabolism in esophageal squamous cell carcinoma via H3K9me3-mediated TFRC silencing.
Shi X, An Z, Cheng S, Yao J, Zhang Y, Zhang L, Cheng X, Cui Y, Wang Y
Biochemical pharmacology 2025 Nov;241:117135
Biochemical pharmacology 2025 Nov;241:117135
STN1 Shields CTC1 From TRIM32-Mediated Ubiquitination to Prevent Cellular Aging.
Lan Y, Liang X, Kuang G, Ma T, Zhang F, Huang Z, Wang H, Luo Z, Feng X
Aging cell 2025 Nov;24(11):e70214
Aging cell 2025 Nov;24(11):e70214
Hyperactivation of the m(6)A demethylase FTO to down-regulate SLC7A11/xCT-mediated redox homeostasis and epigenetic remodeling in facial infiltrating lipomatosis.
Chen H, Gao W, Huang Z, Chang SJ, Qiu Y, Sun B, Lin X, Hua C
Free radical biology & medicine 2025 Nov;239:432-448
Free radical biology & medicine 2025 Nov;239:432-448
Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway.
Zheng L, Zhao Z, Chen L, Yang W, Ercolani G, Qin P, Lin B, Han M, Weng Q, Zhang Y, Wu B, Chen M, Yao Z, Fang S, Ji J
Free radical biology & medicine 2025 Nov;239:317-335
Free radical biology & medicine 2025 Nov;239:317-335
Programmed cell death ligand 1 mediates antigen presentation, apoptosis, necrosis, and inflammatory response in Klebsiella pneumoniae-infected macrophages.
Zheng X, Tang W, Tang Q, Wu Q, Shan J
Immunobiology 2025 Nov;230(6):153133
Immunobiology 2025 Nov;230(6):153133
The RNA-binding protein RBM39 scaffolds an m⁶A-dependent RNA decay complex that destabilizes Tat transcripts and restricts HIV-1 reactivation.
Deng X, Xie S, Zhou M, Yuan Q, Wu S, Huang P, Chen M, Zeng J, Guo P, Qin J, Chen C, Liu J, Liu B, He X, Sun L, Zhang H, Li L, Pan T
PLoS biology 2025 Nov;23(11):e3003486
PLoS biology 2025 Nov;23(11):e3003486
Collagen peptides from Skipjack tuna (Katsuwonus pelamis) bones: Composition, characterization, and mechanism of high-fat diet-induced NAFLD amelioration.
Jiang YL, Zhang SY, Wang B, Zeng YH, Xu L, Chi CF
Food research international (Ottawa, Ont.) 2025 Nov;219:117114
Food research international (Ottawa, Ont.) 2025 Nov;219:117114
Eurotium Cristatum fermented instant dark tea prevents obesity and promotes adipose thermogenesis via modulating the gut microbiota.
Wang X, Li Y, Yu P, Zhang L, Wang Y, Yang X, Ren D
Food research international (Ottawa, Ont.) 2025 Nov;219:116969
Food research international (Ottawa, Ont.) 2025 Nov;219:116969
Aristolochic acid I promotes renal tubulointerstitial fibrosis by activating the mannan-binding lectin serine protease 1-complement system.
Wang C, Zhang H, Wang J, Wu H, Ye J, Zhang Q, Jiang B, Chen L, Wang Y, Cheng S, Ying J, Xiang Y, Cheng Y, Zhang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115708
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115708
Synthetic organochlorines exert bone anabolic activity by modulating CCN3 signaling in osteoblasts.
Sun KN, Li SM, Liu Z, Zhao K, Shen M, Liu ZC, Zhou ST, Li YR, Li RZ, Miao JY, He JJ, Jing T, Clemens TL, Lv ZQ, Zhang Q
Environment international 2025 Nov;205:109862
Environment international 2025 Nov;205:109862
TRIB3 promotes endometrial cancer progression through interacting with E2F1 and enhancing PKM2-mediated tumor glycolysis.
Geng F, Wang Y, Cui G, Fan M
Gynecologic oncology 2025 Nov;202:41-52
Gynecologic oncology 2025 Nov;202:41-52
NSUN6 Promotes Gastric Cancer Progression by Stabilizing CEBPZ mRNA in a m(5)C-Dependent Manner.
Guo J, Wu B, Wang S, Huang D, Hu Y
Applied biochemistry and biotechnology 2025 Nov;197(11):7296-7313
Applied biochemistry and biotechnology 2025 Nov;197(11):7296-7313
Blocking Fpr3 ameliorates osteoarthritis by inhibiting NLRP3-mediated chondrocyte pyroptosis.
Zhou B, Huang Y
Cytokine 2025 Nov;195:157020
Cytokine 2025 Nov;195:157020
Olaparib synergy screen reveals Exemestane induces replication stress in triple-negative breast cancer.
Yusoh NA, Su L, Chia SL, Tian X, Ahmad H, Gill MR
Molecular oncology 2025 Nov;19(11):3387-3408
Molecular oncology 2025 Nov;19(11):3387-3408
Activation of IRF2 signaling networks facilitates podocyte pyroptosis in lupus nephritis.
Zhang F, Xie Y, Dang RN, Yu J, Tian XX, Li LJ, Zhou QM, An XM, Chen PL, Luo YQ, Wu YS, Liu J, Zou HM
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167990
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167990
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.
Liu R, Chen Y, Huang H, Li X, Lv J, Jiang L, Jiang H, Wu C, Chen W, Xu H, Zhu Z, Cai H, Xiao J, Yin L, Ni W
British journal of pharmacology 2025 Nov;182(22):5489-5516
British journal of pharmacology 2025 Nov;182(22):5489-5516
Inhibition of spreading depolarizations by targeting GABA(A) receptors and voltage-gated sodium channels improves neurological deficits in rats with traumatic brain injury.
Yan R, Liu Q, Zhang D, Li K, Li Y, Nie Y, Zhang Y, Li P, Mao S, Li H
British journal of pharmacology 2025 Nov;182(21):5247-5268
British journal of pharmacology 2025 Nov;182(21):5247-5268
Biotransformation of steroid hormones by intestinal fungi and their special cytotoxicity on HeLa cancer cells.
Tian M, Han C, Hu Y, Luan S, Tian X, Guo P, Li X, Sui L, Wang C, Ma X, Li D
Bioorganic chemistry 2025 Nov;166:109102
Bioorganic chemistry 2025 Nov;166:109102
Parthenolide alleviates doxorubicin-induced cardiotoxicity via regulation of Cyp1a1 and Nppa and suppression of NLRP3 inflammasome.
Yang Y, Wei S, Liu S, Xie S, Xiao W, Liu J, Xie N, Li W, Zhang B
Journal of traditional and complementary medicine 2025 Nov;15(7):726-735
Journal of traditional and complementary medicine 2025 Nov;15(7):726-735
Salvigenin mitigates neuronal ferroptosis by binding to PI3K and enhancing the interaction between VCP and PI3K in the repair of spinal cord injury.
Yu Y, Xie X, Zhang Y, Xiao S, Dan F, Liu J, Liu Z, Zhou R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157181
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157181
Benzoylpaeoniflorin alleviates ulcerative colitis by inhibiting ferroptosis through targeting phosphogluconic dehydrogenase.
Tang Y, Wang Z, Zhou F, Li L, Sun C, Li L, Tang F, Huang D, Li Z, Tan Y, Pei G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157111
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157111
Early postnatal overnutrition as a contributor to metabolic dysregulation: Insights into hepatic epigenetic mechanisms.
Zheng W, Zhou N, Kuang J, Du S, Zhu D, Ling R, Zhang C, Wang Y, Zhou W, Li X
The Journal of nutritional biochemistry 2025 Nov;145:110022
The Journal of nutritional biochemistry 2025 Nov;145:110022
O-GlcNAcylation of PRDX1 enhances its stability and promotes liver cancer progression via activating LRP6-mediated Wnt signaling.
Dai L, Xu Z, Fan Y, Gao W, Yuan G, He S, Mao L
Cellular signalling 2025 Nov;135:112055
Cellular signalling 2025 Nov;135:112055
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Wang J, Deng J, Sun B, Qiao G, Yang J, Gao Z, Zhang Q, Dong M, Qu P, Wang Z
Cellular signalling 2025 Nov;135:112024
Cellular signalling 2025 Nov;135:112024
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
Liu X, Ji D, Wen Z, Tang Q, Chen Y
Cellular signalling 2025 Nov;135:112013
Cellular signalling 2025 Nov;135:112013
CX-5461 inhibits cell proliferation and induces ferroptosis of colorectal cancer cells by inactivating Nrf2 pathway.
Chang X, Zhang Y, Wang Q, Yang W, Zhang R, Cong X, Xiao W, Piao J, Lin Z, Jin A
Cellular signalling 2025 Nov;135:111998
Cellular signalling 2025 Nov;135:111998
KSRP-mediated Wnt/β-catenin activation promotes follicular thyroid cancer progression and stemness.
Pan KF, Chou HL, Wang WL, Chen BR, Hsiao M, Hua KT, Wu MH
British journal of cancer 2025 Nov;133(8):1111-1121
British journal of cancer 2025 Nov;133(8):1111-1121
Crosstalk between DNA damage and cGAS-STING immune pathway drives neuroinflammation and dopaminergic neurodegeneration in Parkinson's disease.
Khan S, Delotterie DF, Xiao J, Thangavel R, Hori R, Koprich J, Alway SE, McDonald MP, Khan MM
Brain, behavior, and immunity 2025 Nov;130:106065
Brain, behavior, and immunity 2025 Nov;130:106065
Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma.
Zhang S, Jiang L, Cai S, Weng Z, Zhu Y, Cai ZW, Li H, Li Q, Hu LP, Yao HF, Hua R, Zhao Y, Li D, Yang XM, Zhang JF, Jiang SH
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e11726
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e11726
Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma.
Ning YQ, Wang J, Zhang Y, Li H, Jiang Z, Su X, Yang X, Wu X, Wei B, Ying J, Yan J, Li W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09344
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09344
EGFR Targeted Liposomal PROTAC Assisted With Epigenetic Regulation as an Efficient Strategy for Osimertinib-Resistant Lung Cancer Therapy.
Wang D, Liu Y, Chen Y, Dai C, Hu W, Han J, Li Z, Yin F, Zhang Y, Shi C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e10197
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e10197
Polycystin-1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1-Dependent Microfilament Remodeling.
Zhou J, Deng Y, Mei J, Wan M, Xue N, Zong X, Zhou J, Ding J, Yan T, Jiang Y, Xia T, Zheng P, Zhu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e09846
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e09846
Baicalin alleviates oxidative stress in DF-1 cell line via the Mfn2/MAMs/Ca (2+) pathway.
Lin Z, Wang J, Li J, Zheng Y, Zheng B, Li Q, Huang X
Poultry science 2025 Nov;104(11):105818
Poultry science 2025 Nov;104(11):105818
Functional characterization of LSM12 as a driver in uveal melanoma oncogenesis.
Tang J, Sun F, Ren Y, Chen L, Gao Y, Li J, Liu Y, Cheng C, Zhang P, Chen S, Ai S, Mao Y, Su S, Lu R
Advances in ophthalmology practice and research 2025 Nov-Dec;5(4):268-277
Advances in ophthalmology practice and research 2025 Nov-Dec;5(4):268-277
Targeting FAM134B-DDX3X axis inhibiting AKT signaling in hepatocellular carcinoma.
Mo J, Su C, Liu Q, Li P, Xu L, Long X, Liang H, Zhang B, Chen J
Cell death & disease 2025 Nov 6;16(1):797
Cell death & disease 2025 Nov 6;16(1):797
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
Long T, Li X, Zhou Y, Zhu C, Zhang M, Li M, Wei Z
Gene 2025 Nov 5;971:149800
Gene 2025 Nov 5;971:149800
Recombinant live attenuated measles virus-based vaccines inducing comprehensive protection against Ebola and Marburg viruses.
Zhou J, Zhang X, Yao Y, Xie Y, Li F, Wang W, Yan F, Peng C, Zhang B, Wu Y, Cao Z, Peng Y, Gao G, Zhang H, Gong P, Chiu S
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Nov 5;33(11):5470-5488
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Nov 5;33(11):5470-5488
Small nucleolar RNA host gene 1 (SNHG1) facilitates gemcitabine chemosensitivity in gallbladder cancer by regulating the miR-23b-3p/phosphatase and tensin homolog (PTEN) pathway.
Wang H, Gu Y, Guo M, Zhan M, He M, Zhang Y, Yang L, Liu Y
Chinese medical journal 2025 Nov 5;138(21):2783-2792
Chinese medical journal 2025 Nov 5;138(21):2783-2792
Betulinic acid attenuates lipopolysaccharide-induced cardiac injury by promoting mitophagy with enhancing PINK1/Parkin and suppressing BNIP3.
Zhou XR, Meng XF, Zhang YX, Zhang ZY, Jiang CY, Han YP, Yang JT, Qian LB
European journal of pharmacology 2025 Nov 5;1006:178169
European journal of pharmacology 2025 Nov 5;1006:178169
Icariside II ameliorates slow transit constipation by inhibiting macrophage polarization and suppressing the cGAS-STING pathway.
Jiang Z, Yin F, Ping Y, Ma W, Dou X, Li R, Zheng K, Tong Y, Han L, Fu L, Wu B, Sun D
European journal of pharmacology 2025 Nov 5;1006:178166
European journal of pharmacology 2025 Nov 5;1006:178166
VSIG2 hinders gastric cancer progression by suppressing ANXA2-mediated NF-κB pathway activation.
Ni Q, Wang Y, Bian X, Qu Q, Shen B, Niu Y, Yu J, Zhu J
Acta biochimica et biophysica Sinica 2025 Nov 4;57(11):1834-1846
Acta biochimica et biophysica Sinica 2025 Nov 4;57(11):1834-1846
Integrated summary data-based Mendelian randomization and colocalization analysis reveals TNNT3 as a target of Deer-Antler-Ginseng-formula for triple-negative breast cancer.
Jia J, Ma Y, Wu D, Dou Y, Yuan J, Liu F, Shi A
Discover oncology 2025 Nov 4;16(1):2022
Discover oncology 2025 Nov 4;16(1):2022
Osteocyte Neuropeptide Y Aggravates Bone Loss in OVX Mice by Inhibiting Preosteoclast Proliferation and PDGF-BB-Induced Type H Vessel Formation Through PI3K/Akt Signaling Pathway.
Chen Q, Zhang Y
Calcified tissue international 2025 Nov 4;116(1):134
Calcified tissue international 2025 Nov 4;116(1):134
New perspective on postmortem meat quality changes of Esox Lucius: The role of mitophagy-mediated ferroptosis pathway.
Yan W, Li H, Yu X, Chen X, Ma L, Deng X, Zhang J
Food chemistry 2025 Nov 30;493(Pt 2):145797
Food chemistry 2025 Nov 30;493(Pt 2):145797
Active-targeting biomimetic nanosystem for prostate cancer enhances radiotherapy efficacy by inducing ferroptosis.
Hu Z, Li H, Gan K, Li Y, Jiang Y, Zhang K, Li Z, Zhou Y, Lu T, Xu C, Liu S, He L, Yang F, Jiang J, Song H, Wang Y, Guo L, Shi C, Wen W, Han D, Qin W
Journal of nanobiotechnology 2025 Nov 30;24(1):9
Journal of nanobiotechnology 2025 Nov 30;24(1):9
The kinesin motor Kif9 regulates centriolar satellite positioning during interphase.
Vicente JJ, Wagenbach M, Decarreau J, Zelter A, MacCoss MJ, Davis TN, Wordeman L
Current biology : CB 2025 Nov 3;35(21):5119-5135.e4
Current biology : CB 2025 Nov 3;35(21):5119-5135.e4
Long-read sequencing reveals HBV integration patterns and oncogenic impact on early-onset hepatocellular carcinoma.
Wang Y, Yu D, Mei Y, Fu Z, Lin J, Wu D, Yang Y, Yan H
Genome research 2025 Nov 3;35(11):2389-2405
Genome research 2025 Nov 3;35(11):2389-2405
Fragile X mental retardation 1 gene FMR1 promotes proliferation, migration, and invasion of gastric cancer cells via c-MYC.
Han Y, Mao C, Zhou K, Liang M, Zhao L, Hong Y, Zhang J, Hu N, Wu F
Journal of translational medicine 2025 Nov 3;23(1):1210
Journal of translational medicine 2025 Nov 3;23(1):1210
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
Ma CS, Han B, Liu YX, Shi CK, Li DL, Guo JF, Bai M, Meng SC, Zhang LY, Duan MY, He MT
Molecular neurobiology 2025 Nov 29;63(1):219
Molecular neurobiology 2025 Nov 29;63(1):219
Dexmedetomidine enhances anastomotic healing partly via the Wnt/β-catenin pathway in a rat model of colon surgery.
Chen Y, Li CT, Wang JB, Tang WL, Zhao Y, Chen Y, Liao LM, Zhang LC, Lin TH, Cao ZF
World journal of gastroenterology 2025 Nov 28;31(44):112833
World journal of gastroenterology 2025 Nov 28;31(44):112833
TRIM25 degrades BRD7 protein stability through the ubiquitin proteasome pathway to promote breast cancer progression and paclitaxel resistance by activating YB1/Bcl-2 transcription axis.
Xue C, Wei Q, Li M, Wei J, Zheng L, Wu Z, Xin H, Duan Y, Fan S, Xiong W, Li G, Tang F, Deng H, Zhou M
Cell death & disease 2025 Nov 28;16(1):872
Cell death & disease 2025 Nov 28;16(1):872
Protein deglycase DJ-1 deficiency aggravates acute viral myocarditis by promoting apoptosis via reducing Dusp1 expression.
Yan P, Feng S, Li B, Yin W, Wang L, Zhao G, Guo M, Wang Z, Yuan H
Cell death & disease 2025 Nov 28;16(1):866
Cell death & disease 2025 Nov 28;16(1):866
MYC-mediated transcriptional control of splicing factors promotes RNA splicing in activated B lymphocytes.
Li S, Yang C, Li J, Liu Z, Gong F, Ke X, Ruan GX, Huang H
Scientific reports 2025 Nov 28;15(1):42598
Scientific reports 2025 Nov 28;15(1):42598
RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease.
Du J, Du Q, Zhang Y, Gao J, Wang C, Kou B, Jiang Y, Zhao D, Lin J
Cell & bioscience 2025 Nov 28;15(1):164
Cell & bioscience 2025 Nov 28;15(1):164
FeaSion decodes the regulatory landscape and functional diversity of RNA polymerase II CTD phosphorylation.
Zhu J, Bao L, Xu S, Ji X
Science advances 2025 Nov 28;11(48):eadz2345
Science advances 2025 Nov 28;11(48):eadz2345
ADGRG6 Promotes Pancreatic Adenocarcinoma Progression Through the NF-κB/STAT6 Axis and Modulation of the Tumor Immune Microenvironment.
Li L, Yu Z, Lu X, Yang P, Zhang S, Lin Q, Han J
Current issues in molecular biology 2025 Nov 27;47(12)
Current issues in molecular biology 2025 Nov 27;47(12)
Identifying NDUFB2 as a prognostic biomarker for glioblastoma through an exploratory analysis of an anesthesia-related gene signature.
Wei J, Zou L, Liu Q, Xie Y
BMC cancer 2025 Nov 27;26(1):26
BMC cancer 2025 Nov 27;26(1):26
Development of Knockout Cardiac Muscle Cell Lines Using Integrase-Deficient Lentivirus-Mediated CRISPR/Cas9 Gene Editing.
Zhang F, Lu Q, Qian X, Xing Y, Wang W
Biochemical genetics 2025 Nov 27;
Biochemical genetics 2025 Nov 27;
Investigating the impact of MCTP2 on immune suppression and drug resistance in glioblastoma.
Chen Y, Yan X, Huang Q, Pang H, Li C, Su X, Ye Y, Wang Z, Chen Y, Zhou Y
Functional & integrative genomics 2025 Nov 26;25(1):255
Functional & integrative genomics 2025 Nov 26;25(1):255
Preliminary exploration of the role of fibrinogen-like protein 2 in neuroblastoma.
Qi C, Hou X, Zhou H, Ma Y, Wang L, Zhao H, Wu Z, Zhou Y, Duan G
Scientific reports 2025 Nov 26;15(1):42230
Scientific reports 2025 Nov 26;15(1):42230
mRNA caps accumulate in stress granules and are essential for their formation.
Guo M, Feng Y, Qi G, Ma W, He X, Li R, Liu Y, Wang J
Cellular and molecular life sciences : CMLS 2025 Nov 25;82(1):420
Cellular and molecular life sciences : CMLS 2025 Nov 25;82(1):420
GDF11 alleviates glucocorticoid-induced osteonecrosis of the femoral head by regulating angiogenesis via the PI3K-AKT-eNOS pathway.
Liu Z, Yu L, Zhang Y, Liu K, Zhai H, Xu X, Lu Q, Li X, Li Z, Yang J, Li S, Si M, Cheng L, Liu P, Sun H
Communications biology 2025 Nov 25;8(1):1682
Communications biology 2025 Nov 25;8(1):1682
Cancer-associated adipocytes mediate CD8(+)T cell dysfunction via FGF21-driven lipolysis.
Dalangood S, Hu C, Yuan C, Li X, Qiao W, Li H, Zhang R, Li L, Li P, Yu X, Yin W, Lu J, Gui J
Cell reports 2025 Nov 25;44(11):116526
Cell reports 2025 Nov 25;44(11):116526
Eucommia ulmoides Oliver (Duzhong) extract ameliorates cerebral ischemic stroke in mice by remodeling intestinal microbiota and metabolites.
Qi X, Deng M, Li M, Ma W, Zhou Y
Metabolic brain disease 2025 Nov 25;40(8):325
Metabolic brain disease 2025 Nov 25;40(8):325
Positive feedback loop of IGF2BP3/IL6ST/STAT3 facilitates malignant progression in colorectal cancer.
Liu P, Zhou X
Journal of translational medicine 2025 Nov 25;24(1)
Journal of translational medicine 2025 Nov 25;24(1)
Solvent-induced partial cellular fixation decodes proteome-wide drug targets and downstream pathways in living cells.
Yu T, Wang Y, Wang K, Fang Z, Zhu H, Zhang X, Li Y, Ye M
Nature communications 2025 Nov 25;16(1):10475
Nature communications 2025 Nov 25;16(1):10475
Matrine activates high xenophagy to inhibit enterovirus replication.
Li X, Liu Y, Yu X, Guan X, Liu S, Huo W, Zhou X, Cui M, Liu M, Wang C, Huang C, Bai H, Yin S, Bai S, Yu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157522
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157522
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Zheng D, Shu J, Gao B, Yu H, Liu K, Zheng M, Liu X, Chen G, Lin Y, Li Q, Sun Y, Zheng Y, Li B, Yang X, Wang K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Rosmarinic acid alleviates doxorubicin-induced cellular senescence and cardiotoxicity by targeting the 14-3-3/Foxo1 signaling axis.
Fan C, Wu J, Hu S, Xia Y, Wei Z, Tang H, Jin W, Zhang Z, An P, Luo J, Luo Y, Zhu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157482
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157482
Kaempferol ameliorates BMSCs senescence in postmenopausal osteoporosis by targeting Sp1 to activate FUNDC1-mediated mitophagy.
Wang L, Qu Y, Hu Z, Lei P, Tian X, Yang X, Chen S, Li C, Wei B, Li L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157456
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157456
Syringin attenuates Alzheimer's disease-associated neuroinflammation by inhibiting NLRP3 inflammasome activation.
Xu Z, Huang F, Wu Z, Xu K, Huang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157454
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157454
Unveiling tectorigenin: A novel ferroptosis inducer targeting EGFR in bladder cancer.
Zhai J, Tan R, Yuan S, Che B, Xiong K, Lu L, Li Y, Wu C, Zhang Y, Zhang H, Tang K, Tang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157419
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157419
Biochanin A alleviates endothelial cell senescence via epigenetic regulation of the HDAC1/H3K4me3/NFKB1 axis.
Wang X, Tu Q, Mao A, Meng K, Lv J, Li B, Zhang T, Zhang H, Ding Y, Cao Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157385
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157385
Euchrenone A10 attenuates septic lung injury though S100A8/A9-dependent TLR4/MyD88/NF-κB signaling.
Zhou L, Xiao Y, He J, Ren H, Zhao C, Zhang C, Shu X, Chen Y, Chen D, Chen Y, He X, Lian L, Shao J, Wang J, Wang Y, Li C, OuYang J, Li R, Zhang Z, Liu L, Pan H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157336
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157336
Ailanthone targets mitophagy-loaded SIRT4 to facilitate the deacetylation of HIF1α, triggering oxidative stress for gastric carcinoma treatment.
Lian X, Dai M, Xu X, Zhao H, Li S, Liu X, Lian Y, Ma T, Lian X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157283
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157283
Liu-Jun-Zi decoction alleviates metabolic dysfunction-associated steatohepatitis by modulating myogenic irisin mediated skeletal muscle-liver crosstalk.
Wang C, Liu K, Ji J, Ma W, Zhang H, Wang K, Lin Y, Ma C, Wang X, Cheng F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157218
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157218
Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in fungi.
Son YE, Pérez-Arques C, Heitman J
bioRxiv : the preprint server for biology 2025 Nov 25;
bioRxiv : the preprint server for biology 2025 Nov 25;
USP30-AS1 Dictates Breast Cancer Cell Fate and Chemoresistance via a miR-3646/FZD7/Wnt/β-Catenin Circuit.
He Q, Yang S, Xin Q, Jiang Y, Jiang L, Xu N
Current issues in molecular biology 2025 Nov 24;47(12)
Current issues in molecular biology 2025 Nov 24;47(12)
MiR-503-5p mediates cell cycle arrest and fibrosis of peritoneal mesothelial cells with a high peritoneal solute transport status.
Ji O, Xie Y, Lin Y, Li R, Tong Y, Li P, Fang J, Liu Y
BMC nephrology 2025 Nov 24;26(1):662
BMC nephrology 2025 Nov 24;26(1):662
Directed rescue strategy for enhanced implant osteointegration in aged rats.
Li X, Jiang X, He Y, Xiong H, Huang Q, Xu K, Luo XX, Li K, Tao B, Zha K, Wu J, Liu P, Cai K
Nature communications 2025 Nov 24;16(1):10322
Nature communications 2025 Nov 24;16(1):10322
Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders.
Solo KJ, Zhang Y, Bharathi SS, Zhang BB, Richert AC, Schmidt AV, Van't Land C, D'Annibale O, Wood TC, Goetzman ES
JCI insight 2025 Nov 24;10(22)
JCI insight 2025 Nov 24;10(22)
Efficacy and safety of intrathecal human umbilical cord-derived mesenchymal stromal cell therapy for bone cancer pain: a preclinical study.
Zhang J, Li Y, Ren P, Jiang M, Wu P, Wen Q
Stem cell research & therapy 2025 Nov 23;16(1):690
Stem cell research & therapy 2025 Nov 23;16(1):690
Hua Feng Dan protective effect on ischemic stroke through AKT and ERK pathway.
Shu Q, Yuan X, Gao Y, He X, Xu J, Zhang Y, Cao G
Metabolic brain disease 2025 Nov 22;40(8):323
Metabolic brain disease 2025 Nov 22;40(8):323
Trofinetide Improves Cognitive Function in APP/PS1 Mice by Suppressing Inflammation and Apoptosis.
Chen M, Ning Y, Yang H, Jia J
Molecular neurobiology 2025 Nov 21;63(1):129
Molecular neurobiology 2025 Nov 21;63(1):129
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
Miao Z, Long J, Huang B, Yan D, Wang A
iScience 2025 Nov 21;28(11):113892
iScience 2025 Nov 21;28(11):113892
Mutant NPM1 modulates PDCD4 ubiquitination degradation and facilitates leukemogenesis.
Liang C, Ke J, Zhang Z, Guo H, Shang H, Liu D, Li S, Wu F
iScience 2025 Nov 21;28(11):113776
iScience 2025 Nov 21;28(11):113776
A SWI/SNF complex-related genes signature predicts prognosis and immune infiltration in ccRCC with KCNK5 as a novel biomarker.
Xu K, Yan Z, Liu Y, Qiu Q, Ni X, Tang H, Wang L, Chen Z, Liu X
Scientific reports 2025 Nov 21;15(1):41423
Scientific reports 2025 Nov 21;15(1):41423
MAGEA11 promotes GC proliferation, migration, and invasion through activation of E2F1 transcriptional activity.
Shen Q, Lu Z, Dai L, Huang X, Feng Y
Scientific reports 2025 Nov 21;15(1):41416
Scientific reports 2025 Nov 21;15(1):41416
Neuroserpin: A Potential Neuroprotective Agent in Mild Neonatal Hypoxic-Ischaemic Encephalopathy.
Kawashita E, Fukuzaki Y, Fischer J, Shi L, Liao Y, Millar LJ, Zhong P, Hoerder-Suabedissen A, Soares LC, Molnár Z
Cells 2025 Nov 21;14(23)
Cells 2025 Nov 21;14(23)
Effect of OASL on oxaliplatin-induced immunogenic cell death in gastric cancer via the cGAS-STING signaling pathway.
Zhang L, Liu Y, Yang H, Liu L, Wang L, Chai J, Zhao W, Sun D
Cell death discovery 2025 Nov 21;12(1):20
Cell death discovery 2025 Nov 21;12(1):20
Integrative machine learning-driven prognosis and immunotherapy stratification via lactylation-associated gene in ovarian cancer.
Li X, Chen X, Lin S, Yang X, Wu W, Chen X, Bao L, Fang Q, Fan L, Zhang Q, Ma J, Zhu G, Yang D, Wu X, Cheng Z
NPJ precision oncology 2025 Nov 20;9(1):370
NPJ precision oncology 2025 Nov 20;9(1):370
KIF11 variants in familial exudative vitreoretinopathy leading to mTORC1 overactivation and impaired cell cycle progression.
Liu M, Pan S, Dai E, Zhao R
Human genomics 2025 Nov 19;19(1):135
Human genomics 2025 Nov 19;19(1):135
Sodium hexametaphosphate mitigates calcium oxalate stone formation by modulating crystallization and maintaining PPARα signaling.
Xian JY, Peng L, Long J, Chen XW, Huang LH, Sun XY
Urolithiasis 2025 Nov 18;53(1):222
Urolithiasis 2025 Nov 18;53(1):222
Perinuclear theca protein FNDC8 interacts with CCIN and ACTL7A to ensure proper sperm head shaping during spermiogenesis.
Liu JY, Long CH, Wang LY, Ma YJ, Zheng YL, Li W, Wu BB, Wu HB
Zoological research 2025 Nov 18;46(6):1259-1272
Zoological research 2025 Nov 18;46(6):1259-1272
NAT10 induces N4-acetylcytidine modification of AdipoR1-mediated mitochondrial biogenesis against endothelial-to-mesenchymal transition in hypertension.
Pan H, Song L, Cheng Z, Zhu J, Zhou J, Xu Z, Zhang M
Molecular medicine (Cambridge, Mass.) 2025 Nov 18;31(1):332
Molecular medicine (Cambridge, Mass.) 2025 Nov 18;31(1):332
PTPRK promotes resiniferatoxin-induced postherpetic neuralgia via activating DUSP1/p38 MAPK signaling pathway in dorsal root ganglia.
Zhao Y, Zhang H, Wang Z, Zhu M, Zhang X, Zhang D
Scientific reports 2025 Nov 18;15(1):40630
Scientific reports 2025 Nov 18;15(1):40630
Knockdown of PATZ1 alleviates chronic heart failure through the USP22/HIF-1α axis.
Luo Y, Zhou F, Chen Q, Cai H, Yao K, Deng X
Scientific reports 2025 Nov 18;15(1):40566
Scientific reports 2025 Nov 18;15(1):40566
Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss.
Wang Z, Huang C, Liu S, Xiao P, Lu Z, Xu Y, Tian Y
Communications biology 2025 Nov 17;8(1):1590
Communications biology 2025 Nov 17;8(1):1590
Assessing the toxicological effects of exposure to environmental pollutants PET-MPs on vascular diseases: insights from network toxicology, molecular docking, molecular dynamics, and experimental validation.
Xu H, Chen S, Wang X, Lian H, Zhang S, Liu Z, Guo R
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127082
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127082
Antimony exposure induces bladder cancer metastasis via activation of the SUMOylation-dependent TGF-β/Smad2/3 axis.
Yi B, Zhao Z, Gao X, Zhao D, Liu X, Zhang W, Zhang Z, Zhang C
Environmental research 2025 Nov 15;285(Pt 4):122589
Environmental research 2025 Nov 15;285(Pt 4):122589
Ceftriaxone ameliorates tau phosphorylation and mislocalization in APP/PS1 AD mice by inhibiting endoplasmic reticulum stress.
Feng NN, Li L, Liu LZ, He RB, Xian XH, Liu LR, Hu YY, Li WB
Neuropharmacology 2025 Nov 15;279:110600
Neuropharmacology 2025 Nov 15;279:110600
Key targets of brain-gut coordination in Wuzhuyu decoction treating chronic migraine based on proteomics.
Li M, Song Z, Wang K, Wang Q, Guo X, Zhou Z, Xu J, Wu S, Gong M
Journal of pharmaceutical and biomedical analysis 2025 Nov 15;265:117064
Journal of pharmaceutical and biomedical analysis 2025 Nov 15;265:117064
Farnesoid X Receptor Agonist INT-787 Inhibits Hepatic Mitochondrial Dysfunction in a Diet-Induced ob/ob Mouse Model of MASH.
Di Pasqua LG, Palladini G, Croce AC, Milanesi G, Cavallo M, Adorini L, Ferrigno A, Vairetti M
International journal of molecular sciences 2025 Nov 14;26(22)
International journal of molecular sciences 2025 Nov 14;26(22)
INHBA promotes chemoresistance in pancreatic cancer by enhancing CTPS1 stability and mediating pyrimidine metabolism.
Sun X, Wei Z, Liao X, Zheng D, Li F, Chen L, Gong Y, Ran S, Han X, He Z, Yu C
Cancer cell international 2025 Nov 14;25(1):403
Cancer cell international 2025 Nov 14;25(1):403
Aβ impairs bone vascular homeostasis in APP/PS1 mice via disrupting the mitochondrial fission-efferocytosis axis in macrophages.
Liu T, Zhang W, Bao W, Wang X, Zhang F, Guo J, Li M
International immunopharmacology 2025 Nov 14;165:115526
International immunopharmacology 2025 Nov 14;165:115526
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
Li J, Cui H, Sun X, Zhu L, Li J, Liu R, Li Z
International immunopharmacology 2025 Nov 14;165:115509
International immunopharmacology 2025 Nov 14;165:115509
Empagliflozin alleviates hepatic ischemia-reperfusion injury by inhibiting c-Myc through the JAK1-STAT3 signaling pathway.
Tulahong A, Xu X, Zhou T, Ruze R, Yuan Z, Qiao P, Jiang T, Aji T, Shao Y
International immunopharmacology 2025 Nov 14;165:115508
International immunopharmacology 2025 Nov 14;165:115508
AMSC-EVs attenuate acute kidney injury through TXNIP-IKKα/NFκB signaling-mediated renal CX3CR1(+) macrophage polarization.
Deng WJ, Tang R, Ma MQ, Zhang H, Cao CC
Stem cell research & therapy 2025 Nov 14;16(1):639
Stem cell research & therapy 2025 Nov 14;16(1):639
Comprehensive analysis of ALYREF gene expression and its correlation with immunotherapy efficacy and circulating tumor cells in bladder cancer.
Tang Z, Peng J, Wei Z, Wu S, Guan G, Lu F, Lu B, Zeng S
Scientific reports 2025 Nov 14;15(1):40032
Scientific reports 2025 Nov 14;15(1):40032
Discovery of Cdc20/Hsp90 Dual-Target Inhibitors with Potent Antitumor Activity for Therapy of Acquired Resistant Melanoma.
Chen Q, Le X, Wen Q, Cao S, Guo Y, Weng X, Zhang L, Wei J, Zou M, Hu L, Li Q, Liu S, Chen Z
Journal of medicinal chemistry 2025 Nov 13;68(21):22428-22454
Journal of medicinal chemistry 2025 Nov 13;68(21):22428-22454
NAP1L4 in hepatocellular carcinoma progression and treatment from gene expression to clinical impact.
Lin J, Yin H, Xie Z, Liu M, Kong L, Yao R, Chen G, Li Y, Shen J, Wang Q, Han K, Xu H, Gao Y
Discover oncology 2025 Nov 13;16(1):2202
Discover oncology 2025 Nov 13;16(1):2202
CpG ODN Activates TLR9 and Upregulates TLR3 via the p38 MAPK-ATF3 Signaling Axis to Synergistically Enhance Dendritic Cell Vaccine Efficacy.
Zhou L, Lei Z, Jiang Q, Xu L, Wang Q, Huang Y, Lei T
Cells 2025 Nov 13;14(22)
Cells 2025 Nov 13;14(22)
S100A6 Regulated by PATZ1 Promotes Liver Fibrosis by Activating Hepatic Stellate Cells.
Xue Q, Peng F, Guo C, Zhou Y, Zhong L, Huang L, Li S, Deng L, Zhao J
Digestive diseases and sciences 2025 Nov 13;
Digestive diseases and sciences 2025 Nov 13;
NDC80 promotes epithelial to mesenchymal transition of esophageal squamous cell carcinoma through macrophages polarization and PI3K/AKT pathway activation.
Shu J, Yang C, Sun Z, Liang Y, Zhao N, Liu X, Li Y, Tabish MS, Sun M, Chen K
European journal of medical research 2025 Nov 10;30(1):1092
European journal of medical research 2025 Nov 10;30(1):1092
Neuroglobin-promoted autophagy inhibits the proliferation, migration and invasion of human glioblastoma cells through the EGFR/PI3K/AKT/mTOR signaling pathway.
Li L, Zhang H, Li W, Yuan Z, Zhao W, Luo Z
Journal of translational medicine 2025 Nov 10;23(1):1248
Journal of translational medicine 2025 Nov 10;23(1):1248
Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota homostasis in rats.
Yu Q, Liao H, Tan W, Xu L, Lin G, Ai Z, Xie Q, Liu Y, Li Y, Yang X, Su Z, Ma G, Xie J, Lai Z
Chemico-biological interactions 2025 Nov 1;421:111783
Chemico-biological interactions 2025 Nov 1;421:111783
Ferroptosis-driven neurobehavioral impairment in zebrafish embryos: Mechanistic links to developmental dibutyl phthalate exposure.
Hou T, Guo Y, Tao L, Fan X
Environmental pollution (Barking, Essex : 1987) 2025 Nov 1;384:127009
Environmental pollution (Barking, Essex : 1987) 2025 Nov 1;384:127009
Potentiated fractalkine signaling axis affects neuroinflammation in 1,2-dichloroethane- intoxicated mice via divergent modulating ways on microglial hyperactivation.
Yang J, Yang J, Hu H, Jiang W, Zhang X, Wang G, Zhao F, Liao Y, Jin Y
Ecotoxicology and environmental safety 2025 Nov 1;306:119322
Ecotoxicology and environmental safety 2025 Nov 1;306:119322
Effects of EP-1 exposure during lactation on the emotion, social behavior, gonadal metabolomics, and related receptors in the brains of adult offspring in Kunming mice.
Wu C, Cheng M, Zhang J, Ji X, Chen P, Yu P
Physiology & behavior 2025 Nov 1;301:115057
Physiology & behavior 2025 Nov 1;301:115057
Pantothenic acid-mediated inhibition of microglial inflammation via the JAK2/STAT3 pathway enhances motor function recovery after Spinal cord injury.
Fang Y, Zhang C, Yang Z, Zhao X, Yongcheng Yin, Zhengxin Jin, Zhu P, Ning B
Neuropharmacology 2025 Nov 1;278:110591
Neuropharmacology 2025 Nov 1;278:110591
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Huang HJ, Lin YC, Ho LJ, Su RY, Liu WC, Chiu HW
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
Activation of TRPA1 prevents metabolic dysfunction-associated steatotic liver disease in diet-induced obese mice through stimulating the AMPK/CPT1A signaling pathway.
Wang D, Liu S, Wan J, Chen S, Feng K, Hou J, Yang Y, Wang P
Journal of physiology and biochemistry 2025 May;81(2):359-373
Journal of physiology and biochemistry 2025 May;81(2):359-373
Modulation of Osteogenic Differentiation by CYBB in Osteoporotic Models.
Wang Z, Xu C, Liu Y, Duan K, Zhu Z, Guan J
IUBMB life 2025 May;77(5):e70023
IUBMB life 2025 May;77(5):e70023
Isowalsuranolide targets TrxR1/2 and triggers lysosomal biogenesis and autophagy via the p53-TFEB/TFE3 axis.
Yang X, Ding X, Zhao Y, Wang Y, Dong X, Niu Z, Gu Z, Fei J, Zhao Y, Hao X
Science China. Life sciences 2025 May;68(5):1437-1451
Science China. Life sciences 2025 May;68(5):1437-1451
Beta-aminoisobutyric acid attenuates doxorubicin-induced cardiotoxicity through the adenosine 5'-monophosphate-activated protein kinase-mediated pathway.
Huang J, Sun M, Yu J, Guo Y, Li B, Dai L, Tang Y, Wang X, Han S, Lai X
Xenobiotica; the fate of foreign compounds in biological systems 2025 May;55(5):436-443
Xenobiotica; the fate of foreign compounds in biological systems 2025 May;55(5):436-443
Polystyrene microplastics trigger colonic inflammation in rats via the TLR4/NF-κB/COX-2 pathway and modulation of intestinal microbiota.
Feng X, Zhang M, Zhao T, Cui J, Ye H, Zhou C, Ye L, Zhou L
Toxicology 2025 May;513:154090
Toxicology 2025 May;513:154090
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
Cheng Y, Liu B, Xin J, Wu X, Li W, Shang J, Wu J, Zhang Z, Xu B, Du M, Cheng G, Wang M
Nature aging 2025 May;5(5):909-928
Nature aging 2025 May;5(5):909-928
Methyltransferase-like enzyme 14 exacerbates retinal ganglion cell damage and diabetic retinopathy through N6-methyladenosine-dependent upregulation of pleckstrin homology domain and leucine rich repeat protein phosphatase 2.
Chen L, Wei T, Liu X, Cui L, Hu C, Quan Y
Toxicology and applied pharmacology 2025 May;498:117304
Toxicology and applied pharmacology 2025 May;498:117304
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
Gao H, Shi L, Liu J, Zhao Y, Du F, He Y, Yang X, Song N, Wen J, Zheng G
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
Human umbilical cord mesenchymal stem cells improve bone marrow hematopoiesis through regulation of bone marrow adipose tissue.
Feng J, Zhang M, Ren H, Ren Y, Hao Z, Bian S, Cui J, Li S, Xu J, Daniel MM, Ren F, Xu Z, Tan Y, Chen X, Zhang Y, Chang J, Wang H
Molecular and cellular biochemistry 2025 May;480(5):3033-3049
Molecular and cellular biochemistry 2025 May;480(5):3033-3049
The Role of CXCL13 in GC-1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Through JAK2/STAT3 Signaling Pathway.
Lei Y, Dong R, Sun C, Hu Y, Yan Y, Song G, Wang Y
Journal of applied toxicology : JAT 2025 May;45(5):830-840
Journal of applied toxicology : JAT 2025 May;45(5):830-840
Tetrahydropalmatine promotes macrophage autophagy by inhibiting the AMPK/mTOR pathway to attenuate atherosclerosis.
Wang H, Ding K, He J, Wang J
Histology and histopathology 2025 May;40(5):697-710
Histology and histopathology 2025 May;40(5):697-710
Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.
Sadhu N, Dalan R, Jain PR, Lee CJM, Pakkiri LS, Tay KY, Mina TH, Low D, Min Y, Ackers-Johnson M, Thi TT, Kota VG, Shi Y, Liu Y, Yu H, Lai V, Yang Y, Tay D, Ng HK, Wang X, Wong KE, Lam M, Guan XL, Bertin N, Wong E, Best J, Sarangarajan R, Elliott P, Riboli E, Lee J, Lee ES, Ngeow J, Tan P, Cheung C, Drum CL, Foo RS, Michelotti GA, Yu H, Sheridan PA, Loh M, Chambers JC
Nature cardiovascular research 2025 May;4(5):567-583
Nature cardiovascular research 2025 May;4(5):567-583
FOXC1 Aggravates the Ischemia-Reperfusion Induced Injury in Renal Tubular Epithelial Cells by Activating NF-κB/NLRP3 Signaling.
Qiu D, Zhao N, Chen Q, Wang M
Journal of biochemical and molecular toxicology 2025 May;39(5):e70301
Journal of biochemical and molecular toxicology 2025 May;39(5):e70301
Dihydroartemisinin Targets the NFIC/FBN1 Cascade to Enhance Wound Healing in Chronic Skin Ulcer by Inhibiting Fibroblast Ferroptosis.
Wei Z, Wang B, Fang X, Cheng J
Journal of biochemical and molecular toxicology 2025 May;39(5):e70297
Journal of biochemical and molecular toxicology 2025 May;39(5):e70297
HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB.
Li R, Li Q, Yang C, Liu H, Xiao Y, Yang P, Gong G, Wu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 May;34(5):108280
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 May;34(5):108280
Activation of sigma 1 receptor attenuates doxorubicin-induced cardiotoxicity by alleviating oxidative stress, mitochondria dysfunction, ER stress-related apoptosis, and autophagy impairment.
Al-Maamari A, Sultan M, Wu S, Zhang T, Wang C, Han B, Duan Y, Ding SS, Chen N, Zhang H, Sun F, Chen X, Yu D, Su S
International journal of biological macromolecules 2025 May;310(Pt 4):143549
International journal of biological macromolecules 2025 May;310(Pt 4):143549
HuMSCs-derived exosomal YBX1 participates in oxidative damage repair in granulosa cells by stabilizing COX5B mRNA in an m5C-dependent manner.
Zhu X, Lu M, Li WX, Lin L, Liu Y, Zhou J, Shang J, Shi X, Lu J, Xing J, Zhang M, Zhao S, Zhao D
International journal of biological macromolecules 2025 May;310(Pt 4):143288
International journal of biological macromolecules 2025 May;310(Pt 4):143288
Exosomes derived from baicalin‑pretreated mesenchymal stem cells mitigate atherosclerosis by regulating the SIRT1/NF‑κB signaling pathway.
Yang X, Wu W, Huang W, Fang J, Chen Y, Chen X, Lin X, He Y
Molecular medicine reports 2025 May;31(5)
Molecular medicine reports 2025 May;31(5)
Lactoferrin ameliorates cognitive impairment in D-galactose-induced aging mice by regulating the PI3K/Akt/mTOR signaling pathway and the microbiome-gut-brain axis.
Wang M, Wang Y, Wang X, Qiu Y, Li C, Li H, Li H, Yu J
International journal of biological macromolecules 2025 May;309(Pt 4):143033
International journal of biological macromolecules 2025 May;309(Pt 4):143033
MTA1-DT promotes endometrial cancer growth by modulating G2/M-related gene transcription via PURα.
Liu Y, Li X, Wang F, Cai J, Li Z, Huang Y, Duan X, Liu X, He Y, Xu G, Lu Q
International journal of biological macromolecules 2025 May;309(Pt 4):142943
International journal of biological macromolecules 2025 May;309(Pt 4):142943
SERTAD3 interacts with porcine reproductive and respiratory syndrome virus nonstructural protein 9 and inhibits virus replication.
Chen Y, Li S, Long X, Wang J, He Z, Guo C
International journal of biological macromolecules 2025 May;309(Pt 1):142828
International journal of biological macromolecules 2025 May;309(Pt 1):142828
Salidroside attenuates NASH through regulating bile acid-FXR/TGR5 signaling pathway via targeting gut microbiota.
Zhang J, Zhou J, He Z, Xia Z, Liu H, Wu Y, Chen S, Wu B, Li H
International journal of biological macromolecules 2025 May;307(Pt 4):142276
International journal of biological macromolecules 2025 May;307(Pt 4):142276
Matrix metallopeptidase 2-responsive curcumin-loaded nanoparticles-induced signal transducer and activator of transcription 3 inhibition suppresses glioblastoma multiforme growth via enhancing nuclear factor erythroid 2-related factor 2 activity.
Jia F, Peng Y, Li X, Yang S, Xie Y, Han Y, Huang M, Liu T, Zou W, Chen L, Liang Z
International journal of biological macromolecules 2025 May;307(Pt 2):141998
International journal of biological macromolecules 2025 May;307(Pt 2):141998
Z-VAD(OMe)-FMK suppresses Seneca Valley Virus replication by targeting the active sites of the 3C protease.
Wu L, Yuan Y, Zhao Z, Yan Y, Wang H, Li X
International journal of biological macromolecules 2025 May;306(Pt 3):141587
International journal of biological macromolecules 2025 May;306(Pt 3):141587
RAB4B and Japanese encephalitis virus E protein interaction is essential for viral entry in early endosomes.
Miao C, Zhao Q, Zhang YT, Luo SQ, Han X, Wen Y, Wu R, Yan QG, Huang X, Wang Y, Zhao S, Lang YF, Zheng Y, Zhao F, Du S, Cao SJ
International journal of biological macromolecules 2025 May;306(Pt 2):141452
International journal of biological macromolecules 2025 May;306(Pt 2):141452
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Cai Y, Xu H, Deng K, Yang H, Zhao B, Zhang C, Li S, Wei Z, Wang Z, Wang F, Zhang Y
International journal of biological macromolecules 2025 May;306(Pt 1):141271
International journal of biological macromolecules 2025 May;306(Pt 1):141271
Konjac glucomannan/sodium alginate/ε-poly-l-lysine hydrogel promotes esophageal and colonic wound healing.
Zhou T, Liu Z, Xu L, Mao X, Jin H, Xiong Y, Chen G, Lv Y, Cen L, Wang C, Zhang Y, Ye K, Shen Q, Zhou J, Lv B, Dai J, Yu C, Shen Z
International journal of biological macromolecules 2025 May;306(Pt 1):141146
International journal of biological macromolecules 2025 May;306(Pt 1):141146
S5092 inhibit ASFV infection by targeting the pS273R protease activity in vitro.
Liu C, Li T, Huang T, Zhao G, Wang X, Li J, Huang L, Zhang Z, Zheng J, Weng C
Veterinary microbiology 2025 May;304:110473
Veterinary microbiology 2025 May;304:110473
Extracellular vesicles engineered to directly target encephalomyocarditis virus ameliorates multi-organ viremia in a lethal infection model.
Yue J, Yang Y, Idris A, Jin W, Zhang Y, Chen Y, Li X, Li H, Li S, Wen Y, Feng R, Xie J
Veterinary microbiology 2025 May;304:110448
Veterinary microbiology 2025 May;304:110448
Paeonol Improves Cardiac Remodelling in MI Mice by Suppressing NOX2 mRNA Expression to Mitigate Oxidative Stress and Mitochondrial Dysfunction.
Liu Y, Wu Z, Jin X, Ji M, Huang T, Meng P, Xu T, You W, Zhao Y, Ye F, Wu X
Journal of cellular and molecular medicine 2025 May;29(9):e70563
Journal of cellular and molecular medicine 2025 May;29(9):e70563
UBE2T is a diagnostic and prognostic biomarker for endometrial cancer.
Wang L, Wang M, Wang Z, Wang K, Zhao B, Wang Y, Zheng J, Zhang S
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 May;27(5):2067-2083
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 May;27(5):2067-2083
V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging.
Hashmi F, Kane PM
Aging cell 2025 May;24(5):e14487
Aging cell 2025 May;24(5):e14487
Baicalin restores dopamine homeostasis in the ADHD model by regulating DAT-VMAT2 transport imbalance through activation of the Nrf2/Keap-1/HO-1 pathway.
Ding X, Ma B, Zhou R, Zhang Y, Zhang Y, Xie X, Wang M, Wu C, Jia J
Free radical biology & medicine 2025 May;232:107-127
Free radical biology & medicine 2025 May;232:107-127
Lingguizhugan Decoction improves chronic heart failure by synergistically modulating ?1-AR/Gs/GRKs/?-arrestin signaling bias.
Guo S, Xia L, Yang S, Liang Y, Shan X, Zhao P, Guo W, Zhang C, Xu M, Sun N, Lu R, Chen H
Chinese journal of natural medicines 2025 May;23(5):560-571
Chinese journal of natural medicines 2025 May;23(5):560-571
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Lv X, Deng H, Li C, Gao W, Zhang Y, Gao Y, Zhao B, Shi C, Gao J, Liu Z
Brain research bulletin 2025 May;224:111327
Brain research bulletin 2025 May;224:111327
Genome-scale CRISPR screen identifies TMEM198 driving double membrane vesicle formation in swine alphacoronavirus and murine betacoronavirus infected cells.
Shi L, Zhang Y, Duan Y, Sun M, Yuan C, Cao L, Kong X, Zhang W, Zheng H, Wang Q
PLoS pathogens 2025 May;21(5):e1013211
PLoS pathogens 2025 May;21(5):e1013211
Restoration of lysosomal function attenuates autophagic flux impairment in nucleus pulposus cells and protects against mechanical overloading-induced intervertebral disc degeneration.
Liu S, Hu Y, Xu W, Liu W, Wang B, Zeng X, Shao Z, Yang C, Xiong L, Cai X
Autophagy 2025 May;21(5):979-995
Autophagy 2025 May;21(5):979-995
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Shen H, Xie Y, Wang Y, Xie Y, Wang Y, Su Z, Zhao L, Yao S, Cao X, Liang J, Long J, Zhong R, Tang J, Wang S, Zhang L, Wang X, Stork B, Cui L, Wu W
Autophagy 2025 May;21(5):1096-1115
Autophagy 2025 May;21(5):1096-1115
Tetrahedral DNA Nanostructure-Modified Nanocoating for Improved Bioaffinity and Osseointegration of Titanium.
Qian C, Chen S, Chen L, Zhang C, Yang L, Li Q, Kang B, Chen X, Mei P, Gu H, Liu Y, Liu Y
Small (Weinheim an der Bergstrasse, Germany) 2025 May;21(18):e2412747
Small (Weinheim an der Bergstrasse, Germany) 2025 May;21(18):e2412747
EPA-enriched lipid from Apostichopus japonicus byproducts mitigates UVB-induced oxidative stress and inflammation by gut-skin axis.
Qu C, Liang S, Wang K, He Y, Ju W, Sun Y, Miao J
Food research international (Ottawa, Ont.) 2025 May;208:116085
Food research international (Ottawa, Ont.) 2025 May;208:116085
Circular RNA ATP9A Stimulates Non-small Cell Lung Cancer Progression via MicroRNA-582-3p/Ribosomal Protein Large P0 Axis and Activating Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.
Wang D, Huang W, Li G
Applied biochemistry and biotechnology 2025 May;197(5):3166-3183
Applied biochemistry and biotechnology 2025 May;197(5):3166-3183
Compound C1 reduced inflammation and activated autophagy in alveolar macrophages in mice.
Sheng Q, Zhao J, Chen S, Zeng J, Wang S, Wang J
Molecular immunology 2025 May;181:139-147
Molecular immunology 2025 May;181:139-147
Specnuezhenide and ecliptasaponin A from Ligustrum lucidum Ait and Ecliptae Herba improved premature ovarian failure by targeting the ESR1.
Xu J, Lei L, Li P, Huang ZC, Meng Y, He B, Kuang JL
Journal of pharmacological sciences 2025 May;158(1):13-26
Journal of pharmacological sciences 2025 May;158(1):13-26
Shenqi granules enhance recovery from cerebral ischemia-reperfusion injury by modulating tryptophan and tyrosine metabolism and activating NFE2L2/NRF2.
Liu HX, Yang MK, Li YC, Liu CX, Li GP, Meng XL, Pei K, Wen SY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156623
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156623
Piperlongumine alleviates viral myocarditis by inhibiting pyroptosis through NF-κB pathway.
Li H, Wang M, Hua Z, Guo H, Qiu Y, Zhang Z, Zou Y, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156606
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156606
Liensinine overcomes EGFR-TKI resistance in lung adenocarcinoma through DRP1-mediated autophagy.
Chen Y, Shu C, Yan Z, Zhang S, Zhang W, Zhao J, Wang A, Li J, Zeng Y, Zhu J, Huang JA, Liu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156593
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156593
Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade.
Lin Y, Zhang J, Gao X, Wu Z, Yang L, Tian K, Lv X, Li J, Chen K, Zhang Y, Hu H, Zhu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156586
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156586
Effective compound combination of Bufei Yishen formula ameliorates PM2.5-induced COPD by inhibiting mitochondrial oxidative stress through SIRT3-mediated FOXO3 deacetylation.
Wang J, Yue H, Dong Y, Liu T, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156568
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156568
Procyanidins inhibit alphacoronavirus infection by reducing interferon antagonism.
Liu Y, Wang X, Wang X, Mao W, Weng Y, Zhao Y, Duan C, Wang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156549
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156549
Study on the mechanism of Trichosanthes kirilowii Maxim. against COPD based on serum chemical composition analysis, network pharmacology, and experimental study.
Shi P, Zheng B, Cao Y, Niu G, Guo Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156533
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156533
NOP2-Mediated m5C Methylation Modification of LMNB2 mRNA Facilitates Colorectal Cancer Progression.
Bi J, Huang Y, Hu W, Liu Y
Cancer medicine 2025 May;14(10):e70970
Cancer medicine 2025 May;14(10):e70970
LAMP3 exacerbates autophagy-mediated neuronal damage through NF-kB in microglia.
Jia K, Shen R, Li Y, Shi W, Xia W
Cellular signalling 2025 May;129:111658
Cellular signalling 2025 May;129:111658
Dectin-1 participates in neuroinflammation and dopaminergic neurodegeneration through synergistic signaling crosstalk with TLR4.
Xue F, Zhang M, Zhao RY, Wang XW, Gu Y, Yang Y, Chen WF
Brain, behavior, and immunity 2025 May;126:260-273
Brain, behavior, and immunity 2025 May;126:260-273
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization.
Qiu H, Liu J, You J, Zhou O, Hao C, Shu Y, Ma D, Zou W, Zhang L, Liu E, Luo Z, Ren L, Geng G, Zou L, Peng D, Fu Z
Genes & diseases 2025 May;12(3):101244
Genes & diseases 2025 May;12(3):101244
AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple-Negative Breast Cancer.
Sun Z, Xu H, Lu G, Yang C, Gao X, Zhang J, Liu X, Chen Y, Wang K, Guo J, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2408106
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2408106
NEK2 Contributes to the Protection Against Cryptorchidism Outcomes.
Zhou X, Ye S, Wang X, Liang Z, Qian N, Ji L, Xian H, Wang Z, Ge W
Birth defects research 2025 May;117(5):e2485
Birth defects research 2025 May;117(5):e2485
Novel Phenoxyacetic Acid (4-Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site.
Ma Y, Sun Y, Tu Q, Lin F, Mei F, Chen Q, Fu T, Yang L, Lai X, Yang M, Yin T, Lu G, Qi J, Lin H, Wen Z, Yang Y, Han H
Chemical biology & drug design 2025 May;105(5):e70125
Chemical biology & drug design 2025 May;105(5):e70125
Dysfunctional terminal differentiation of satellite cells in the wooden breast muscle of Ross 308 broiler chickens.
Wang X, Xing T, Zhu X, Wang X, Zhao L, Gao F, Zhang L
Poultry science 2025 May;104(5):105041
Poultry science 2025 May;104(5):105041
RAGE/AP-1/OTR signaling pathway in rat hippocampus DG involved in CUS induced depressive-like behaviors.
Li X, Wang X, Xue L, Luo L, Hu L, Jiang W
Behavioural brain research 2025 May 8;485:115540
Behavioural brain research 2025 May 8;485:115540
Mechanistic Insights into the Anti-Hepatocellular Carcinoma Effects of ACY-1215: p53 Acetylation and Ubiquitination Regulation.
Yin Y, Du Y, Xu Y, Zhu Z, Hu Y, Xu L, Yang K, Chen T, Shi Y, Wang C, Zhang Y
Current issues in molecular biology 2025 May 8;47(5)
Current issues in molecular biology 2025 May 8;47(5)
A novel dual CCK/ GLP-1 receptor agonist ameliorates cognitive impairment in 5 × FAD mice by modulating mitophagy via the PINK1/Parkin pathway.
Luo R, Kang Y, Ma H, Zhang Z, Hölscher C, Hao L, Zhang Z
International immunopharmacology 2025 May 8;154:114612
International immunopharmacology 2025 May 8;154:114612
Compound J27 alleviates high-fat diet-induced metabolic dysfunction-associated steatotic liver disease by targeting JNK.
Ye J, Zhu W, Cui Y, Zhang Q, Xiong Y, Jin L, Wang A, Lin M, Dong H, Liang G, Hu X, Luo W
International immunopharmacology 2025 May 8;154:114570
International immunopharmacology 2025 May 8;154:114570
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Zhou J, Wu K, Ma Y, Zhu J, Zhou Y, Zhang Z, Li F, Zeng G, Li S, Tan S, Zhang Y, Wan C, Tu T, Lin Q, Liu Q
International immunopharmacology 2025 May 8;154:114561
International immunopharmacology 2025 May 8;154:114561
The dual effects of propofol down-regulating PD-L1 expression and inhibiting autophagy to reduce cerebral ischemia reperfusion injury.
Sun X, Wang D, Chen Y, Zheng X, Zhang W, Ruan Z, Chen Z
International immunopharmacology 2025 May 8;154:114548
International immunopharmacology 2025 May 8;154:114548
Electroacupuncture ameliorates cognitive impairment and white matter injury in vascular dementia rats via activating HIF-1α/VEGF/VEGFR2 pathway.
Yang Y, Rao T, Jiang Y, Zhan Y, Cheng J, Yin Z, Ma K, Zhong X, Guo X, Yang S
Neuroscience 2025 May 7;573:364-380
Neuroscience 2025 May 7;573:364-380
Pentraxin 3 promotes the expression of pro-inflammatory cytokines and the migration of macrophages in myocarditis.
Zhu T, Ding Y, Wu X, Li Y, Cheng G, Wang N, Yang Q, Zhang W, Chen X, Liu X
BMC cardiovascular disorders 2025 May 7;25(1):354
BMC cardiovascular disorders 2025 May 7;25(1):354
Endoplasmic reticulum protein 29 negatively regulates platelet functions and thrombosis in mice.
Yan X, Lu Y, Lv K, Jiang M, Fang C, Wu Y, Yang A
Thrombosis journal 2025 May 7;23(1):44
Thrombosis journal 2025 May 7;23(1):44
Black Phosphorus-Loaded Gelatin Methacryloyl Hydrogels Enhance Angiogenesis via Activation of the PEAK1-MAPK Pathway.
Xian R, Xian H, Dong H, Lin J, Zhuang X, Zou Y, Xie Q, Liang Y, Li S
ACS applied materials & interfaces 2025 May 7;17(18):26371-26385
ACS applied materials & interfaces 2025 May 7;17(18):26371-26385
Erianin inhibits cell migration and induces apoptosis by inhibiting VEGF-α/PI3K/AKT signaling pathway in malignant melanoma.
Sun H, Wang G, Ren C, Zhang X, Zhao P, Guo B
Scientific reports 2025 May 6;15(1):15766
Scientific reports 2025 May 6;15(1):15766
Fibulin-1 deficiency alleviates liver fibrosis by inhibiting hepatic stellate cell activation via the p38 MAPK pathway.
Zhao W, Zhang J, Guo Q, Wang Q, Zhao H, Xiao F, Han M, Cao Y, Ding R, Yang A, Xie W
Cellular and molecular life sciences : CMLS 2025 May 5;82(1):192
Cellular and molecular life sciences : CMLS 2025 May 5;82(1):192
Ferroptosis Activation Contributes to Kidney Aging in Mice by Promoting Tubular Cell Senescence.
Wang Z, Dai Y, Jin R, Mo D, Hu Q, Huang Y, Zhang L, Zhang C, Gao H, Yan Q
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 May 5;80(6)
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 May 5;80(6)
Lithium with environmentally relevant concentrations interferes with mitochondrial function, antioxidant response, and autophagy processes in Daphnia magna, leading to changes in life-history traits and behavior.
Duan C, Zhao Y, Xiao Y, Hou Y, Gong W, Zhang H, Wang Y, Nie X
Journal of hazardous materials 2025 May 5;488:137420
Journal of hazardous materials 2025 May 5;488:137420
Design, synthesis and optimization of Apcin analogues as Cdc20 inhibitors for triple-negative breast cancer therapy.
Le X, Chen Q, Wen Q, Cao S, Zhang L, Hu L, Hu G, Li Q, Chen Z
European journal of medicinal chemistry 2025 May 5;289:117434
European journal of medicinal chemistry 2025 May 5;289:117434
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
Yao X, Wang X, Zhang R, Kong L, Fan C, Qian Y
Nature communications 2025 May 5;16(1):4170
Nature communications 2025 May 5;16(1):4170
Modulation of senescent Lepr(+) skeletal stem cells via suppression of leptin-induced STAT3‒FGF7 axis activation alleviates abnormal subchondral bone remodeling and osteoarthritis progression.
Yu FH, Yin BF, Liu MY, Zhang WJ, Zhao ZD, Wang L, Li XT, Li PL, Li ZL, Xu RX, Ding L, Zhu H
Stem cell research & therapy 2025 May 5;16(1):227
Stem cell research & therapy 2025 May 5;16(1):227
Bardoxolone methyl suppressed colorectal cancer cells in vitro by inhibiting the PI3K signaling pathway.
Zhang L, Huang Q, Yang J, Hu Y
Scientific reports 2025 May 5;15(1):15710
Scientific reports 2025 May 5;15(1):15710
KRT6A Restricts Influenza A Virus Replication by Inhibiting the Nuclear Import and Assembly of Viral Ribonucleoprotein Complex.
Chang Y, Shan Z, Shi W, Li Q, Wang Y, Wang B, Wang G, Chen H, Jiang L, Li C
Viruses 2025 May 4;17(5)
Viruses 2025 May 4;17(5)
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Jiang S, Bu S, Kang X, Dong Y, Chen L, Yuan L, Shi M, Du M, Liang M, Huang K, Yang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
Enterovirus 71 Induces Mitophagy via PINK1/Parkin Signaling Pathway to Promote Viral Replication.
Tian X, Yuan M, Li L, Chen D, Liu B, Zou X, He M, Wu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70659
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70659
A Novel Role of Adipokine 'Intelectin-1': Ameliorating Renal Fibrosis Through Inhibition of Renal Tubular Epithelial Cell Senescence.
Zhang Y, Shen M, Zhang B, Li X, Cheng H, Feng D, Han Y, Luo Z, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70653
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70653
LCLAT1 as a Potential Biomarker for Predicting Clinical Prognosis, Tumor Immunity, and Therapeutic Efficacy in Hepatocellular Carcinoma.
Wang W, Lv Z, Zhou X, Zhang W, Cheng Q, Ji W, Shao Y, Yu J, Xu H, Yang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70625
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70625
Mechanism of adenosine monophosphate-activated protein kinase promoting lower extremity varicose veins development via cytoskeletal dynamics.
Zhang Y, Ju Z, Dai K, Wan L, Zhou G, Ji Y, Qiu J
BMC cardiovascular disorders 2025 May 31;25(1):423
BMC cardiovascular disorders 2025 May 31;25(1):423
Hippocampal Proteomics Reveals the Novel Molecular Profiling of Postnatal Lead (Pb) Exposure on Autism-like Behaviors.
Liu L, Zhou X, Ma Z, Liu R, Zhang Y, Wang Y, Liu Y, Xia X, Wang J
Toxics 2025 May 31;13(6)
Toxics 2025 May 31;13(6)
TRPC6-targeted dexamethasone nanobubbles with ultrasound-guided theranostics for adriamycin-induced nephropathy.
Wu L, Liu Y, Fu Z, Guo H, Liu K, Ren J, Huang Z, Yang F, Mao H
Journal of nanobiotechnology 2025 May 30;23(1):398
Journal of nanobiotechnology 2025 May 30;23(1):398
A critical role for IL-21/IL-21 receptor signaling in isoproterenol-induced cardiac remodeling.
Qi B, Xu R, Jin Y, Wang Y, Cheng T, Liu C, Ji Y, Guo L, Li J, Gao Y, Xu Y, Cui J, Liu J, Jiang Z, Feng L, Qi Z, Yang L
Scientific reports 2025 May 30;15(1):18985
Scientific reports 2025 May 30;15(1):18985
The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma.
Li Z, Xu H, Chen H, Chen L, Zang H, Qian Y
Translational cancer research 2025 May 30;14(5):3175-3185
Translational cancer research 2025 May 30;14(5):3175-3185
Calpain1 inhibition enhances autophagy-lysosomal pathway and ameliorates tubulointerstitial fibrosis in Nephronophthisis.
Li D, Zhang J, Su X, Yang Y, Lai J, Wei X, Chen H, Liu Y, Wang H, Sun L
Molecular medicine (Cambridge, Mass.) 2025 May 3;31(1):166
Molecular medicine (Cambridge, Mass.) 2025 May 3;31(1):166
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Xu H, Cai Y, Yang H, Zhang C, Liu W, Zhao B, Wang F, Zhang Y
Communications biology 2025 May 29;8(1):824
Communications biology 2025 May 29;8(1):824
Activation of the MEK1-CHK2 axis in macrophages by Staphylococcus aureus promotes mitophagy, resulting in a reduction in bactericidal efficacy.
Wu X, Guan X, Cheng C, Deng Z, Li Z, Ma Y, Xie Y, Zheng Q
Molecular medicine (Cambridge, Mass.) 2025 May 29;31(1):211
Molecular medicine (Cambridge, Mass.) 2025 May 29;31(1):211
Copper-Induced DRP1 Activation Disrupts Mitochondrial-Lipid Droplet Contact to Promote Hepatic Steatosis.
Li Q, Su L, Guo P, Liao J, Tang Z
Journal of agricultural and food chemistry 2025 May 28;73(21):13006-13020
Journal of agricultural and food chemistry 2025 May 28;73(21):13006-13020
Aryl Hydrocarbon Receptor-Dependent miRNA-382-5p Mediates the Classical Pyroptosis Induced by Foodborne Benzo(a)pyrene through Targeting IκB in Liver.
Meng Y, Jia Y, He Z, Li J, Yuan L
Journal of agricultural and food chemistry 2025 May 28;73(21):12978-12992
Journal of agricultural and food chemistry 2025 May 28;73(21):12978-12992
Tylophora yunnanensis extract inhibits cholesterol biosynthesis to suppress triple negative breast cancer.
Feng ZH, Li WY, Li QZ, Zhao FB, Zhang HJ, Zhang L, Zhang H
Journal of ethnopharmacology 2025 May 28;348:119877
Journal of ethnopharmacology 2025 May 28;348:119877
IGF-1 signaling pathway activation promotes axonal regeneration and repair: A mechanism study on catalpol-induced functional recovery after ischemic stroke.
Liu Y, Wu D, Hua H, Mei S, Yan X, Xu X, Li L, Wu Y, Zhu J, Wu M, Li W
Journal of ethnopharmacology 2025 May 28;348:119808
Journal of ethnopharmacology 2025 May 28;348:119808
Cryptotanshinone alleviates cerebral ischemia reperfusion injury by regulating ferroptosis through the PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway.
Gao N, Huang Z, Xie J, Gao S, Wang B, Feng H, Bao C, Tian H, Liu X
Journal of ethnopharmacology 2025 May 28;348:119800
Journal of ethnopharmacology 2025 May 28;348:119800
Pyrotinib promotes the antitumor effect of T-DM1 by increasing drug endocytosis in HER2-positive breast cancer.
Ren W, Liu J, Zhao R, Zhao F, Zhang Y, Mu J, Zhu T
Scientific reports 2025 May 28;15(1):18625
Scientific reports 2025 May 28;15(1):18625
NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation.
Liu Z, Lu H, Zhang X, Tang S, Lin A, Han S, Ma X
Cell death discovery 2025 May 28;11(1):257
Cell death discovery 2025 May 28;11(1):257
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
Zou W, Kou L, Wang Y, Jin Z, Xiong N, Wang T, Xia Y
NPJ Parkinson's disease 2025 May 28;11(1):141
NPJ Parkinson's disease 2025 May 28;11(1):141
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway.
Wang JM, Zhang FH, Xie HY, Liu ZX, Tang YJ, Shu X, Wu YQ, Lu DH, Sun JZ, Ying YF, Ma XY, Zheng XY, Wang X, Liu B, Li JF, Xie LP, Luo JD
Cell reports 2025 May 27;44(5):115595
Cell reports 2025 May 27;44(5):115595
Elevated CEP72 expression facilitates the progression of hepatocellular carcinoma and is associated with unfavorable outcomes.
Tan N, Wei Q
Discover oncology 2025 May 27;16(1):937
Discover oncology 2025 May 27;16(1):937
Dihydroartemisinin alleviates diethylnitrosamine-induced hepatocarcinogenesis by targeting a novel MAZ/TRIM50 axis.
Liu R, Huang Y, Li D, Cui H, Tang Y, Hu Y, Xu L, Lin C, Qi G, Chen L, Zhang Z, Tan S, Zhu X
International immunopharmacology 2025 May 27;156:114733
International immunopharmacology 2025 May 27;156:114733
Therapeutic potential of CHI3L1 in osteoarthritis: Inhibition of cartilage matrix degradation and inflammation through TLR4-MAPK-STAT1 pathway.
Meng C, Chen S, Liu Q, Xu H, He Y, Qu Y, Li J, Zhou R, Hou Y, Huang X, You H
International immunopharmacology 2025 May 27;156:114684
International immunopharmacology 2025 May 27;156:114684
LncRNA SNHG15 promotes angiogenesis and improves cardiac repair after myocardial infarction through MiR-665-mediated KDR expression.
Liang X, Liu S, Liu G, Fan Q, Ma F, Yin Y, Li Z, Wu Y, Zheng M
Cellular and molecular life sciences : CMLS 2025 May 26;82(1):211
Cellular and molecular life sciences : CMLS 2025 May 26;82(1):211
Integrative Single-Cell and Bulk RNA Sequencing Identifies a Glycolysis-Related Prognostic Signature for Predicting Prognosis in Pancreatic Cancer.
Wu N, Zhou C, Yan X, Liu Z, Jiang R, Luo Y, Jiang P, Mu Y, Xiao S, Huang X, Zhou Y, Sun D, Jin Y
International journal of molecular sciences 2025 May 26;26(11)
International journal of molecular sciences 2025 May 26;26(11)
The oncogenic role of TIMM8A in cancer and the mechanistic insights into the function in breast cancer cells.
Wang W, Liu M, Wu H, Li J, Lv W, Li C, Du C, Feng C, Zhang Y, Cai Y, Jia Y, Hu Y, Qu J, Zhang S, Wu F
Scientific reports 2025 May 26;15(1):18374
Scientific reports 2025 May 26;15(1):18374
Erucin Alleviates Cardiac Hypertrophy by Improving Mitochondrial Function via Nrf2-Sirt3 Pathway.
Jiang S, Wang C, Dong Y, Chen L, Shi M, Zhang F, Wang Z, Liang M
Phytotherapy research : PTR 2025 May 26;
Phytotherapy research : PTR 2025 May 26;
ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity.
Zhou S, Hua S, Chen X, Ni M, Liu J, Wang Y, Wu W, Ding A, Qin Z, Yang X, Chen X, Zhu B, Wu H
Chinese medicine 2025 May 25;20(1):68
Chinese medicine 2025 May 25;20(1):68
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
Wang X, Chang M, Feng K, Wang Q, Li B, Gao W
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
FBXO10 Drives Hepatocellular Carcinoma Proliferation via K63-Linked Ubiquitination and Stabilization of FRMPD1.
Liu W, Xu B, Kifayat K, Xie Y, Liu X, Dong C, Wang L
Current issues in molecular biology 2025 May 24;47(6)
Current issues in molecular biology 2025 May 24;47(6)
CIRBP Enhances the Function of Yak Cumulus Cells by Activating AMPK/mTOR-Mediated Mitophagy.
Zhang R, Cui Y, Pan Y, Wang M, Yu S, Xu R, Ma W, Wang J, Zhong D, Jiao Z
Biomolecules 2025 May 24;15(6)
Biomolecules 2025 May 24;15(6)
Integration of network pharmacology, transcriptomics, and experimental verification to investigate the mechanism of action of cepharanthine hydrochloride against prostate cancer.
Dong Z, Chang X, Luo X, Li H, Deng M, Huang Z, Chen T, Chen Y, Sun B, Wu Y, Wu R, Wu Q, Zhu J, Zheng J
Scientific reports 2025 May 24;15(1):18115
Scientific reports 2025 May 24;15(1):18115
Taletrectinib promotes pyroptosis in colorectal carcinoma via SRC/AKT/mTOR axis inhibition.
Zhang T, Zou Y, Zhang SH, Wang YY, He S, Yuan W, Yang M, Liu T, Deng SH, Wu DM, Xu Y
Scientific reports 2025 May 24;15(1):18049
Scientific reports 2025 May 24;15(1):18049
Single-cell imaging of N4-acetylcytidine-modified RNA using fluorine metabolic labeling mediated proximity ligation assay.
Wang Q, Du Y, Yan S, Lu Z, Tang Y, Xiao F, Zhou F, Zhou X
Nucleic acids research 2025 May 22;53(10)
Nucleic acids research 2025 May 22;53(10)
Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes.
Takemoto M, Sugishita Y, Takahashi-Suzuki Y, Fujiya H, Niki H, Yudoh K
International journal of molecular sciences 2025 May 22;26(11)
International journal of molecular sciences 2025 May 22;26(11)
Identification of m5C RNA modification-related gene signature for predicting prognosis and immune microenvironment-related characteristics of heart failure.
Liu Z, Feng R, Xu Y, Liu M, Wang H, Lu Y, Wang W, Wang J, Zou C
Hereditas 2025 May 22;162(1):83
Hereditas 2025 May 22;162(1):83
MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer.
Huang Y, Yang T, Yang C, Tang B, Su B, Yang X
Scientific reports 2025 May 22;15(1):17870
Scientific reports 2025 May 22;15(1):17870
Selenoprotein K Confers Protection against Iron Dyshomeostasis-Related Neurotoxicity by Regulating the Palmitoylation of TfR-1.
Jia SZ, Li Y, Xu XW, Huang YP, Deng XY, Zhang ZH, Song GL
Journal of agricultural and food chemistry 2025 May 21;73(20):12233-12246
Journal of agricultural and food chemistry 2025 May 21;73(20):12233-12246
Inhibition of Farnesoid-x-receptor signaling during abdominal sepsis by dysbiosis exacerbates gut barrier dysfunction.
Qian S, Su Z, Lin J, Hou Q, Wang X, Li Y, Wang J, Huang C, Wang Z, Cubero FJ, Wang X, Liao L
Cell communication and signaling : CCS 2025 May 21;23(1):236
Cell communication and signaling : CCS 2025 May 21;23(1):236
Caveolin-1 negatively regulates the calcitonin receptor-like receptor and neuroinflammation in a female mouse model of migraine.
Zhou Y, Chen W, Zhang Y, Yang L, Lu F, Yan W, Xie Q, Huang Y, Huang W, Wang L, Zeng Z, Xiao Z
Journal of neuroinflammation 2025 May 21;22(1):134
Journal of neuroinflammation 2025 May 21;22(1):134
Iron Replacement Attenuates Hypoxic Pulmonary Hypertension by Remodeling Energy Metabolism via Regulating the HIF2α/Mitochondrial Complex I, III/ROS Axis.
Geng Y, Wang H, Bai Z, Ge R
Biomolecules 2025 May 21;15(5)
Biomolecules 2025 May 21;15(5)
DJ-1 deficiency and aging: dual drivers of retinal mitochondrial dysfunction.
Upadhyay M, Sturgis J, Bhattacharyya S, Jiang K, Hagstrom SA, Bonilha VL
bioRxiv : the preprint server for biology 2025 May 21;
bioRxiv : the preprint server for biology 2025 May 21;
Silencing of LncRNA XIST Suppressed Tumor Growth and Metastasis in Papillary Thyroid Carcinoma by Modulating miR-204/FN1 Axis.
Qiu J, Sun M, Qin Z, Liu M, Zhang W
ACS omega 2025 May 20;10(19):19643-19654
ACS omega 2025 May 20;10(19):19643-19654
Study on Cellular Mechanism of Improving Inflammatory Effect of Gastrodin.
Zheng X, Gong T, Yu W, Xu S, Tang C, Zhong Y, Zhu Z
The Tohoku journal of experimental medicine 2025 May 2;265(4):249-259
The Tohoku journal of experimental medicine 2025 May 2;265(4):249-259
Microcystin-LR induces lung injury in mice through the NF-κB/NLRP3 pathway.
Zhang Y, Guan Y, Dai M, Yang Y, Yang F
Journal of toxicology and environmental health. Part A 2025 May 19;88(10):385-394
Journal of toxicology and environmental health. Part A 2025 May 19;88(10):385-394
B cell dysfunction in thalamus and brainstem involvement and high lactate caused by novel mutation of EARS2 gene.
Wen Y, Huang Y, Zhang W, Chen P, Hu X, Xiong X, Luo L
Italian journal of pediatrics 2025 May 19;51(1):143
Italian journal of pediatrics 2025 May 19;51(1):143
Amelioration of Acetaminophen-Induced Hepatic Oxidative Stress and Inflammation by RNAi Targeting Cyp2e1 In Vivo.
Liu W, Huan L, Zhang C, Yin R, Ouyang Z, Wei Y
Current issues in molecular biology 2025 May 19;47(5)
Current issues in molecular biology 2025 May 19;47(5)
To verify the biological characteristics of disulfidptosis associated gene ADORA2B in esophageal cancer.
Cui Y, Deng Y, Wu Z, Sun X
BMC gastroenterology 2025 May 19;25(1):382
BMC gastroenterology 2025 May 19;25(1):382
Synergistic regulation of DACH1 stability by acetylation and deubiquitination promotes colorectal cancer progression.
Zhu L, Cheng C, Li H, Liu J, Wu Y, Wu L, Yao H
Cell death & disease 2025 May 19;16(1):400
Cell death & disease 2025 May 19;16(1):400
Inhibition of TPI1 Sensitizes Cisplatin-Resistant Oral Cancer to Ferroptosis.
Wang D, Zheng H, Chen Y, Hao J, Zhou Y, Li N
Biomedicines 2025 May 19;13(5)
Biomedicines 2025 May 19;13(5)
Impaired Mitophagy Contributes to Pyroptosis in Sarcopenic Obesity Zebrafish Skeletal Muscle.
Tang X, Zou Y, Yang S, Chen Z, Zhou Z, Peng X, Tang C
Nutrients 2025 May 18;17(10)
Nutrients 2025 May 18;17(10)
Outer membrane vesicles of Porphyromonas gingivalis impede bone regeneration by inducing ferroptosis via the Hippo-YAP signaling pathway.
Luo X, Wang Y, Ning T, Lei Q, Cui H, Zou X, Chen Y, Chen S, Zhang X, Tan S, Ma D
Journal of nanobiotechnology 2025 May 17;23(1):358
Journal of nanobiotechnology 2025 May 17;23(1):358
Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions.
Malik V, Huang X, Zhou H, Bojar R, Soni RK, Landry DW, Jelic S, Wang J
iScience 2025 May 16;28(5):112510
iScience 2025 May 16;28(5):112510
LncRNA NEAT1 participates in diminished ovarian reserve by affecting granulosa cell apoptosis and estradiol synthesis via the miR-204-5p/ESR1 axis.
Dong L, Wu H, Qi F, Chen W, Xu Y, Li M, Wang Y, Yan R, Cai P
Journal of ovarian research 2025 May 16;18(1):102
Journal of ovarian research 2025 May 16;18(1):102
Inhibition of hsa_circ_0003314 contributes to trophoblast cell migration and invasion and inhibits pyroptosis in preeclampsia.
Zhou Y, Chen Y, Li L, Lin L
Histochemistry and cell biology 2025 May 16;163(1):52
Histochemistry and cell biology 2025 May 16;163(1):52
Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway.
Deng J, Li Y, Zhang L, Liao W, Liu T, Shen F
Discover oncology 2025 May 16;16(1):787
Discover oncology 2025 May 16;16(1):787
Ursolic acid suppresses ferroptosis by modulating Th17/Treg balance and gut dysbiosis in experimental autoimmune thyroiditis rats.
Mou L, Huang B, Xie W, Li B, Hong Z, Huang X, Liu X, Zhang Y
International immunopharmacology 2025 May 16;155:114569
International immunopharmacology 2025 May 16;155:114569
Identification of liver proteins as biomarker for postmortem diagnosis of heat stroke through proteomics.
Pan M, Liu H, Sun T, Ma C, Yang L, Dong H
Scientific reports 2025 May 16;15(1):17075
Scientific reports 2025 May 16;15(1):17075
METTL3 promotes osteogenesis by regulating N6-methyladenosine-dependent primary processing of hsa-miR-4526.
Song Y, Gao H, Pan Y, Gu Y, Sun W, Liu J
Stem cells (Dayton, Ohio) 2025 May 15;43(5)
Stem cells (Dayton, Ohio) 2025 May 15;43(5)
Trimethylamine N-oxide induces cardiac diastolic dysfunction by down-regulating Piezo1 in mice with heart failure with preserved ejection fraction.
Chen Q, Zhang H, Chen Y, Peng Y, Yao Y, Xue H, Guo Q, Tian D, Xiao L, Teng X, Zheng M, Xiao B, Wu Y, Jin S
Life sciences 2025 May 15;369:123554
Life sciences 2025 May 15;369:123554
ZLN005, a PGC-1α agonist, delays photoreceptor degeneration by enhancing mitochondrial biogenesis in a murine model of retinitis pigmentosa.
Hu C, Ren C, Wu Y, Lin R, Shen T, Li T, Yu D, Jiang L, Wan Z, Luo Y, Su T, Yu J, Qiu Y
Neuropharmacology 2025 May 15;269:110361
Neuropharmacology 2025 May 15;269:110361
Endoplasmic reticulum stress and forkhead box protein O1 inhibition mediate palmitic acid and high glucose-induced β-cell dedifferentiation.
Wang LK, Kong CC, Yu TY, Sun HS, Yang L, Sun Y, Li MY, Wang W
World journal of diabetes 2025 May 15;16(5):95431
World journal of diabetes 2025 May 15;16(5):95431
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Ma T, Guo WW, Zhang M, He W, Dongzhi C, Gongye X, Xia P, Chai Y, Chen Z, Zhu Y, Qu C, Liu J, Yang Z, Ma W, Tian M, Yuan Y
Cell death & disease 2025 May 15;16(1):382
Cell death & disease 2025 May 15;16(1):382
Atractylenolide I Inhibits Nicotine-Induced Macrophage Pyroptosis and Alleviates Atherogenesis by Suppressing the TLR4/ROS/TXNIP/NLRP3 Pathway.
Li HH, Liu X, Wang YP, Xu X, Zhu L, Zhang W, Ren K
Metabolites 2025 May 15;15(5)
Metabolites 2025 May 15;15(5)
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury.
Zeng Y, Wu R, He Y, Zhang Q, Wang Z, Qin P, Yang F, Han Y, Hao M, Zheng Y, Gao L, Chen X, Zhao X, Zeng Z, Lian ZX, Xiao W, Liu Z, Zhao ZB, Gong S
Cell host & microbe 2025 May 14;33(5):688-704.e10
Cell host & microbe 2025 May 14;33(5):688-704.e10
Targeting GPR84 to alleviate acute immune-mediated liver injury.
Zheng Y, Wang Y, Xu Y, Shen S, Xu H, Hu C, Chen Y, Teng F, Pan J, Zheng S, Wang J, Su Z, You Q
Molecular medicine (Cambridge, Mass.) 2025 May 14;31(1):187
Molecular medicine (Cambridge, Mass.) 2025 May 14;31(1):187
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Dong R, Li M, Gu XF, Gao H, Wei Z, Qi H, Zhang J, Feng Q
Journal of translational medicine 2025 May 14;23(1):540
Journal of translational medicine 2025 May 14;23(1):540
Cellular SLC35B4 promotes internalization during influenza A virus entry.
Wang G, Jiang L, Yan Y, Kong F, Li Q, Zhang J, Hou S, Wang B, Wang X, Kong H, Deng G, Shi J, Tian G, Zeng X, Chen H, Li C
mBio 2025 May 14;16(5):e0019425
mBio 2025 May 14;16(5):e0019425
Human umbilical cord mesenchymal stem cell therapy for atopic dermatitis through inhibition of neutrophil chemotaxis.
Shao J, Xie Z, Ye Z, Chen G, Wang Y, Zhang L, Liu F, Zhang S, Lin X, Wang J, Chen Y, Chen Y, Pan X, Wu F, Pan R, Liang J, Zhang L
Stem cell research & therapy 2025 May 14;16(1):243
Stem cell research & therapy 2025 May 14;16(1):243
ROS-responsive dextran-benzeneboronic acid pinacol ester micelles encapsulating edaravone for the treatment and mechanism of cerebral ischemia-reperfusion injury.
Zhao H, Yang P, Zhang M, Zheng W, Qi R, Zhu X, Li J, Li S
Metabolic brain disease 2025 May 13;40(5):202
Metabolic brain disease 2025 May 13;40(5):202
JAK2/STAT3/HMGCS2 signaling aggravates mitochondrial dysfunction and oxidative stress in hyperuricemia-induced cardiac dysfunction.
Peng D, He X, Ren B, Wang Q, Peng L, Jiang Y, Huo S, Men L, Shi W, Luo P, Zhu M, Zhang C, Lv J, Lin L, Li S
Molecular medicine (Cambridge, Mass.) 2025 May 13;31(1):184
Molecular medicine (Cambridge, Mass.) 2025 May 13;31(1):184
Gut microbiota-derived glutathione from metformin treatment alleviates intestinal ferroptosis induced by ischemia/reperfusion.
Wang F, Wang X, Wang C, Yan W, Xu J, Song Z, Su M, Zeng J, Han Q, Ruan G, Zhang E, Wang W
BMC medicine 2025 May 13;23(1):285
BMC medicine 2025 May 13;23(1):285
Dysregulation of miR-106a-5p/PTEN axis associated with progression and diagnostic of postmenopausal osteoporosis.
Liu X, Zhang X, Cen M
Journal of orthopaedic surgery and research 2025 May 13;20(1):456
Journal of orthopaedic surgery and research 2025 May 13;20(1):456
Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms.
Zhang J, Li Z, Song X, Cai P, Liu Q
Scientific reports 2025 May 13;15(1):16664
Scientific reports 2025 May 13;15(1):16664
The potential of secretogranin V as a prognostic biomarker in non-small cell lung cancer.
Zhang W, Wang R, Guo R, Wang Y, Wang H, Li Y, Li X, Song J
Scientific reports 2025 May 13;15(1):16589
Scientific reports 2025 May 13;15(1):16589
Bufei Yishen formula alleviates airway epithelial cell senescence in COPD by activating AMPK-Sirt1-FoxO3a pathway and promoting autophagy.
Cheng M, Yang M, Tian Y, Liu X, Li J, Zhao P
Scientific reports 2025 May 13;15(1):16584
Scientific reports 2025 May 13;15(1):16584
Synaptic and cognitive impairment associated with L444P heterozygous glucocerebrosidase mutation.
Lado W, Ham A, Li H, Zhang H, Chang AY, Sardi SP, Alcalay RN, Arancio O, Przedborski S, Tang G
Brain : a journal of neurology 2025 May 13;148(5):1621-1638
Brain : a journal of neurology 2025 May 13;148(5):1621-1638
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Zhao DP, Xue A, Yuan K, Zuo K, Li Y, Bian ZH, Xu HD, Cheng SM, Yang M, Zhao HM, Ma X, Lei X, Zhang N
Journal of ethnopharmacology 2025 May 12;347:119792
Journal of ethnopharmacology 2025 May 12;347:119792
Phillyrin from Forsythia suspensa suppresses the proliferation, angiogenesis, and metastasis of colorectal cancer via targeting CD147.
Huang Y, Cheng N, Zhi Y, Qiao D, Wang Y, Ma M, Ge C, Tao W, Liu W
Journal of ethnopharmacology 2025 May 12;347:119759
Journal of ethnopharmacology 2025 May 12;347:119759
Dendrobium nobile lindl extract modulates integrin αIIbβ3-mediated signaling pathways to inhibit platelet activation and thrombosis.
Hua C, Wu M, Xiao Y, Zhang R, Yuan Y, Zhang L, Guo F, Liu J, Yang Z, Liu G
Journal of ethnopharmacology 2025 May 12;347:119728
Journal of ethnopharmacology 2025 May 12;347:119728
Exploration of the pharmacological substance basis and efficacy evaluation of fufang she-she-cao (Hedyotis diffusa formula) in repressing gastric cancer.
Chen DH, Mao PJ, Diao WJ, Lu JQ, Wu SL, Li Q
Journal of ethnopharmacology 2025 May 12;347:119711
Journal of ethnopharmacology 2025 May 12;347:119711
Unravelling lumbar disc herniation severity beyond MRI : integrated transcriptomic and metabolomic analyses highlight glycerophospholipid metabolism and inform a machine-learning diagnostic model: a pilot study.
Deng Q, Ren S, Zhang N, Li G, Yu Z, Li X, Cui H, Zhang Y, Zhang Y, Chen J
Bone & joint research 2025 May 12;14(5):434-447
Bone & joint research 2025 May 12;14(5):434-447
Enhanced Osteogenic Activity of a Titanium Mesh Modified with Magnesium-Doped Nanowires for Peri-Implant Guided Bone Regeneration: In Vitro and In Vivo.
Shen Z, Zhu YW, Wei YW, Zhou Y, Xu Y, Chen W, Qiu J
ACS biomaterials science & engineering 2025 May 12;11(5):2664-2676
ACS biomaterials science & engineering 2025 May 12;11(5):2664-2676
HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression.
Kong F, Bao E, Zhong Y, Wang Y, Liu R, Zhang H, Yang L, Jiang R, Liu X, Li C, Liu X, Pan X, Zheng K, You H, Tang R
Hepatology communications 2025 May 1;9(5)
Hepatology communications 2025 May 1;9(5)
Aberrant phase separation drives membranous organelle remodeling and tumorigenesis.
Wang X, Jiang A, Meng Q, Jiang T, Lu H, Geng X, Song Z, Hu X, Yu Z, Xu W, Ning C, Lin Y, Li D
Molecular cell 2025 May 1;85(9):1852-1867.e10
Molecular cell 2025 May 1;85(9):1852-1867.e10
Formononetin prevents intestinal injury caused by radiotherapy in colorectal cancer mice via the Keap1-Nrf2 signaling pathway.
Tang R, Zhang L, Lou J, Mo W, Zhao L, Li L, Zhang K, Yu Q
Biochemical and biophysical research communications 2025 May 1;761:151676
Biochemical and biophysical research communications 2025 May 1;761:151676
SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma.
Nie J, Tang J, Zhang Z, Sun H, Wang X, Wang L, Wang M, Huang W, Gao Y, Li J, Cheng C, Su S, Chen S, Ai S, Mao Y, Zhang P, Liu Y, Lu R
Investigative ophthalmology & visual science 2025 May 1;66(5):24
Investigative ophthalmology & visual science 2025 May 1;66(5):24
Mechanism of arsenic regulation of mitochondrial damage and autophagy induced synaptic damage through SIRT1 and protective effect of melatonin in HT22 cell.
Zhang X, Wang J, Li S, Chen K, Wang L, Feng C, Gao Y, Yan X, Zhao Q, Li B, Zheng J, Qiu Y
Chemico-biological interactions 2025 May 1;412:111461
Chemico-biological interactions 2025 May 1;412:111461
SNORD9 promotes ovarian cancer tumorigenesis via METTL3/IGF2BP2-mediated NFYA m6A modification and is a potential target for antisense oligonucleotide therapy.
Chen S, Wen JT, Zhang S, Wang JL, Yuan J, Bao HJ, Chen X, Zhao Y
Life sciences 2025 May 1;368:123527
Life sciences 2025 May 1;368:123527
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
Li Q, Zhou M, Yang Y, Jiang Y, Chen C, Hu E, Chen J, Wang D
Life sciences 2025 May 1;368:123510
Life sciences 2025 May 1;368:123510
HaloPROTAC3 treatment activates the unfolded protein response of the endoplasmic reticulum in nonengineered mammalian cell lines.
Anisimova AS, Karagöz GE
Molecular biology of the cell 2025 May 1;36(5):mr3
Molecular biology of the cell 2025 May 1;36(5):mr3
BACH1 deficiency improves placental angiogenesis via SLC25A51-mediated mitochondrial NAD(+) transport in intrahepatic cholestasis of pregnancy.
Li S, Zhu W, Xing Z, Chen D, Zhao H, Zhang Y, Zhang W, Sun J, Wu Y, Ai L, Pang Q
Molecular medicine (Cambridge, Mass.) 2025 May 1;31(1):162
Molecular medicine (Cambridge, Mass.) 2025 May 1;31(1):162
Semaglutide and High-Intensity Interval Exercise Attenuate Cognitive Impairment in Type 2 Diabetic Mice via BDNF Modulation.
Lai S, Kang Z, Sun J, Wang Z, Xu Y, Xing S, Feng M, Wang Y, Liu H
Brain sciences 2025 May 1;15(5)
Brain sciences 2025 May 1;15(5)
A heterodimeric radioligand labeled with gallium-68 targeting fibroblast activation protein.
Xie C, Peng L, Nie H, Yang T, Wu R, Zhang D, Wen F, Chen J, Xue L, Zhang X, Zha Z, Wang J
EJNMMI research 2025 May 1;15(1):52
EJNMMI research 2025 May 1;15(1):52
Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions.
Han QQ, Ren QD, Guo X, Farag MA, Zhang YH, Zhang MQ, Chen YY, Sun ST, Sun JY, Li NY, Liu C
Journal of advanced research 2025 Mar;69:449-461
Journal of advanced research 2025 Mar;69:449-461
Exploring the mechanism of tiRNA-Val-CAC-002 in the pathogenesis of oral submucous fibrosis.
Zeng L, Peng H, Sun L, Yu H, Wu Y
Journal of oral biosciences 2025 Mar;67(1):100588
Journal of oral biosciences 2025 Mar;67(1):100588
Long non‑coding RNA ABHD11‑AS1 inhibits colorectal cancer progression through interacting with EGFR to suppress the EGFR/ERK signaling pathway.
Tan S, Li S, Xia L, Jiang X, Ren Z, Peng Q, Peng M, Yang W, Xu X, Oyang L, Shen M, Wang J, Li H, Wu N, Tang Y, Liao Q, Lin J, Zhou Y
International journal of oncology 2025 Mar;66(3)
International journal of oncology 2025 Mar;66(3)
Thermal Ageing of Black Garlic Enhances Cellular Antioxidant Potential Through the Activation of the Nrf2-Mediated Pathway.
Yu SS, Chu YL, Tung YC, Su ZY
Food technology and biotechnology 2025 Mar;63(1):36-45
Food technology and biotechnology 2025 Mar;63(1):36-45
Allocryptopine Attenuates Inflammatory Responses in Microglial Cells Via TLR4-Dependent NF-κB and p38 MAPK Pathways.
Nigdelioglu Dolanbay S, Şirin S, Aslim B
Molecular neurobiology 2025 Mar;62(3):3833-3847
Molecular neurobiology 2025 Mar;62(3):3833-3847
TDP-43/ALKBH5-mediated m(6)A modification of CDC25A mRNA promotes glioblastoma growth by facilitating G1/S cell cycle transition.
Zhang Y, Xie S, Li W, Gu J, Zhang XA, Ni B, Wang Z, Yang R, Song H, Zhong Y, Huang P, Zhou J, Cao Y, Guo J, Liu Y, Qi S, Wang H
MedComm 2025 Mar;6(3):e70108
MedComm 2025 Mar;6(3):e70108
Exercise-induced Activation of SIRT1/BDNF/mTORC1 Signaling Pathway: A Novel Mechanism to Reduce Neuroinflammation and Improve Post-stroke Depression.
Tang J, Lu L, Yuan J, Feng L
Actas espanolas de psiquiatria 2025 Mar;53(2):366-378
Actas espanolas de psiquiatria 2025 Mar;53(2):366-378
COPB1 deficiency triggers osteoporosis with elevated iron stores by inducing osteoblast ferroptosis.
Wang Y, Zhang R, Wang A, Wang X, Wang X, Zhang J, Liu G, Huang K, Liu B, Hu Y, Pan S, Ruze X, Zhai Q, Xu Y
Journal of orthopaedic translation 2025 Mar;51:312-328
Journal of orthopaedic translation 2025 Mar;51:312-328
The potential role of the SIRT1-Nrf2 signaling pathway in alleviating hidden hearing loss via antioxidant stress.
Zheng Z, Zhang P, Fu Y, Jiang Y, Zhu J, Wang F, Li S, Zhang Z, Chang T, Li T, Zhang M, Ruan B, Wang X
Cell biology international 2025 Mar;49(3):262-276
Cell biology international 2025 Mar;49(3):262-276
THRA1/PGC-1α/SIRT3 pathway regulates oxidative stress and is implicated in hypertension of maternal hypothyroid rat offspring.
Guo J, Shi Y, Yu X, Zhao Y, Wei B, Huo M, Lu L, Li L, Gao Q, Sun M
Hypertension research : official journal of the Japanese Society of Hypertension 2025 Mar;48(3):1080-1098
Hypertension research : official journal of the Japanese Society of Hypertension 2025 Mar;48(3):1080-1098
Assessment of cardiotoxicity induced by PFOS exposure and mechanism research via untarget metabolomics.
Yang J, Guo M, Wu J, Li F, Xu S, Wang J, Wu F
Drug and chemical toxicology 2025 Mar;48(2):303-313
Drug and chemical toxicology 2025 Mar;48(2):303-313
BMAL1 improves assisted reproductive technology outcomes in patients with polycystic ovary syndrome by targeting BMP6 and regulating ovarian granulosa cell apoptosis.
Liang Q, Wei C, Guan L, Chen W, Ding S, Wu H
Journal of assisted reproduction and genetics 2025 Mar;42(3):937-948
Journal of assisted reproduction and genetics 2025 Mar;42(3):937-948
Bergapten Ameliorates Renal Fibrosis by Inhibiting Ferroptosis.
Li L, Cai W, Zhang H, Tang J, Yang Y, Huang Y, Xi Q, Zhang R
Phytotherapy research : PTR 2025 Mar;39(3):1355-1371
Phytotherapy research : PTR 2025 Mar;39(3):1355-1371
Liraglutide improves senescence and ameliorating diabetic sarcopenia via the YAP-TAZ pathway.
Xu Q, Qiu X, Di H, Li Z, Liu Z, Liu K
Journal of diabetes and its complications 2025 Mar;39(3):108975
Journal of diabetes and its complications 2025 Mar;39(3):108975
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
Qiao CM, Ma XY, Tan LL, Xia YM, Li T, Wu J, Cui C, Zhao WJ, Shen YQ
Experimental neurology 2025 Mar;385:115142
Experimental neurology 2025 Mar;385:115142
Polydopamine-functionalized nanohydroxyapatite coated exosomes with enhanced cytocompatibility and osteogenesis for bone regeneration.
Xiang M, Zhang G, Liu Y, Liao C, Xiao L, Xiang M, Guan X, Liu J
Bio-medical materials and engineering 2025 Mar;36(2):98-109
Bio-medical materials and engineering 2025 Mar;36(2):98-109
Investigating the role of IL-6 in the pathogenesis of systemic lupus erythematosus: Insights from bone marrow mesenchymal stem cells.
Zhang Z, Zhu S, Li Q, Wei S, Yin L, Zhu J, Yang S, Zhang W, Lai K
Lupus 2025 Mar;34(3):225-233
Lupus 2025 Mar;34(3):225-233
E. coli Nissle 1917 improves gut microbiota composition and serum metabolites to counteract atherosclerosis via the homocitrulline/Caspase 1/NLRP3/GSDMD axis.
Liu H, Ma X, Yang X, Xiao S, Ouyang S, Hu Z, Zhou Z, Jiang Z
International journal of medical microbiology : IJMM 2025 Mar;318:151642
International journal of medical microbiology : IJMM 2025 Mar;318:151642
Eravacycline improves the efficacy of anti-PD1 immunotherapy via AP1/CCL5 mediated M1 macrophage polarization in melanoma.
Liu N, Yan M, Lu C, Tao Q, Wu J, Zhou Z, Chen J, Chen X, Peng C
Biomaterials 2025 Mar;314:122815
Biomaterials 2025 Mar;314:122815
Aloe-Emodin Improves Mitophagy in Alzheimer's Disease via Activating the AMPK/PGC-1α/SIRT3 Signaling Pathway.
Wang Y, Ge Y, Hua S, Shen C, Cai B, Zhao H
CNS neuroscience & therapeutics 2025 Mar;31(3):e70346
CNS neuroscience & therapeutics 2025 Mar;31(3):e70346
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
Wu Y, Liu X, Luo G, Li Q, Guo B, Li L, Nie J
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
Exosomal SphK1 from colorectal cancer cells promotes cancer cell migration and activates hepatic stellate cells.
Zhang W, Xu C
Molecular medicine reports 2025 Mar;31(3)
Molecular medicine reports 2025 Mar;31(3)
A nucleocapsid monoclonal antibody based sandwich ELISA for the general detection of both PRRSV-2 and PRRSV-1.
Sun S, Zhang K, Zhang J, He P, Zhang P, Deng D, Chi C, Jiang S, Zheng W, Chen N, Zhu J
Veterinary microbiology 2025 Mar;302:110399
Veterinary microbiology 2025 Mar;302:110399
Integrating network pharmacology to investigate the mechanism of quercetin's action through AKT inhibition in co-expressed genes associated with polycystic ovary syndrome and endometrial cancer.
Li M, Cui Y, Wu X, Yang X, Huang C, Yu L, Yi P, Chen C
International journal of biological macromolecules 2025 Mar;297:139468
International journal of biological macromolecules 2025 Mar;297:139468
Fatty acid desaturase 2 (FADS2) affects the pluripotency of hESCs by regulating energy metabolism.
Li Z, Li W, Zhang C, Wang J, Geng X, Qu B, Yue Y, Li X
International journal of biological macromolecules 2025 Mar;295:139449
International journal of biological macromolecules 2025 Mar;295:139449
Midnolin Correlates With Anti-Tumour Immunity and Promotes Liver Cancer Progression Through β-Catenin.
Huang S, Zhang J, He T, Zhou J, Liu Z
Journal of cellular and molecular medicine 2025 Mar;29(6):e70472
Journal of cellular and molecular medicine 2025 Mar;29(6):e70472
Chemerin's Role in Endometrial Dysfunction: Insights From Transcriptomic Analysis.
Yu M, Wang Y, Cai J, Dong X, Wang H, Sun Z, Xiao T, Chen J, Li M, Shan C, Dong Y, Zhang JV
Journal of cellular and molecular medicine 2025 Mar;29(6):e70417
Journal of cellular and molecular medicine 2025 Mar;29(6):e70417
Adiponectin facilitates the cell cycle, inhibits cell apoptosis and induces temozolomide resistance in glioblastoma via the Akt/mTOR pathway.
Sun P, Liu F, Huo K, Wang J, Cheng Y, Shang S, Ma W, Yu J, Han J
Oncology letters 2025 Mar;29(3):127
Oncology letters 2025 Mar;29(3):127
PYCR1 Promotes Esophageal Squamous Cell Carcinoma by Interacting With EGFR to Affecting the PI3K/Akt/mTOR Signaling Pathway.
Meng YQ, Feng HM, Li B, Xie Y, Li Z, Li ZQ, Li X
The journal of gene medicine 2025 Mar;27(3):e70017
The journal of gene medicine 2025 Mar;27(3):e70017
Single-cell RNA sequencing and cell-cell communication analysis reveal tumor microenvironment associated with chemotherapy responsiveness in ovarian cancer.
Jiang X, Chen N, Wei Q, Luo X, Liu X, Xie L, Yi P, Xu J
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Mar;27(3):1000-1012
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Mar;27(3):1000-1012
Metformin inhibits EV-A71 and CVA16 infections by regulating TRIB3-SCARB2 axis and activating AMPK.
Wang H, Cui B, Yan H, Wu S, Wang K, Yang G, Jiang J, Li Y
Antiviral research 2025 Mar;235:106081
Antiviral research 2025 Mar;235:106081
Carbon monoxide alleviates endotoxin-induced acute lung injury via NADPH oxidase inhibition in macrophages and neutrophils.
Watabe Y, Giam Chuang VT, Sakai H, Ito C, Enoki Y, Kohno M, Otagiri M, Matsumoto K, Taguchi K
Biochemical pharmacology 2025 Mar;233:116782
Biochemical pharmacology 2025 Mar;233:116782
Anti-inflammatory Fatty Acid Derivatives From Mangrove-derived Actinomycetes Streptomyces sp.
Ge C, Xu H, Zhang XY, Wu GX, Yang M, Gu YQ, Li JL
Chemistry & biodiversity 2025 Mar;22(3):e202401946
Chemistry & biodiversity 2025 Mar;22(3):e202401946
Fibrinogen degradation products exacerbate alpha-synuclein aggregation by inhibiting autophagy via downregulation of Beclin1 in multiple system atrophy.
Liu H, Yu R, Zhang M, Zheng X, Zhong L, Yang W, Luo Y, Huang Z, Zheng J, Zhong H, Wei X, Zheng W, Yu Y, Wang Q
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Mar;22(2):e00538
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Mar;22(2):e00538
LRP1-mediated p-tau propagation contributes to cognitive impairment after chronic neuropathic pain in rats.
Ning Y, Zhang Y, Jiang T, Feng J, Zhan J, Ou C, Wang L
Neuroscience research 2025 Mar;212:84-96
Neuroscience research 2025 Mar;212:84-96
Long-term leucine supplementation increases body weight in goats by controlling appetite and muscle protein synthesis under protein-restricted conditions.
Lv X, Jiang A, Hua J, Liu Z, Yan Q, Tang S, Kang J, Tan Z, Wu J, Zhou C
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:404-418
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:404-418
MiR-592 Attenuates Tamoxifen Resistance in Breast Cancer Through PIK3CA-Mediated PI3K/AKT/mTOR Signaling Pathway.
Jin C, Gao X, Ni J, Zhang B, Wang Z
Applied biochemistry and biotechnology 2025 Mar;197(3):2051-2065
Applied biochemistry and biotechnology 2025 Mar;197(3):2051-2065
Inhibition of autophagy as a novel treatment for neurofibromatosis type 1 tumors.
Stevens M, Wang Y, Bouley SJ, Mandigo TR, Sharma A, Sengupta S, Housden A, Perrimon N, Walker JA, Housden BE
Molecular oncology 2025 Mar;19(3):825-851
Molecular oncology 2025 Mar;19(3):825-851
GPSM1 interacts and cooperates with MMP19 to promote proliferation and EMT in colorectal cancer cells.
Wang L, Li N, Chen Y, Qiao Y, Song Y, Zhang X, Zhao H, Ran W, Li G, Xing X
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119903
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119903
Epithelium-derived exosomal dipeptidyl peptidase-4 involved in arecoline-induced oral submucous fibrosis.
Shieh TM, Lin NC, Shen YW, Lan WC, Shih YH
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167683
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167683
DEF6 regulates renal ischemia reperfusion injury through suppressing the WWP2 mediated ubiquitination of PARP1.
Hu H, Liu Y, Han S, Guo J, Zhou J, Qiu T
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167681
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167681
Renal tubular S100A7a impairs fatty acid oxidation and exacerbates renal fibrosis via both intracellular and extracellular pathway.
Sun P, Chen Q, Chen X, Zhou J, Long T, Ma Y, Zhou M, Hu Z, Tian J, Zhu F, Yang Z, Xie L, Wu Q, Nie J
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167656
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167656
GALNT5 promotes migration and invasion of pancreatic ductal adenocarcinoma cells by activating Erk signaling pathway.
Zheng Y, Lu Y, Yuan F, Kong Y, Mao Y, Wang S
Biochimica et biophysica acta. General subjects 2025 Mar;1869(3):130769
Biochimica et biophysica acta. General subjects 2025 Mar;1869(3):130769
1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells.
Hu MX, Li JQ, Zhang HW, Ma YK, Zhao BJ, Xiao L, Liang W, Wang Y, Wang C, Wu CG, Liu TT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Mar;184:117907
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Mar;184:117907
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Tang H, Wen J, Wang L, Yang Q, Qin T, Ren Y, Zhao Y, Li C, Li J, Cao H, Xu J, Yang Q
Neurochemistry international 2025 Mar;184:105950
Neurochemistry international 2025 Mar;184:105950
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Feng X, Ma Y, Zhao Y, Zhao Z, Song Z, Lin L, Wang W
Molecular immunology 2025 Mar;179:94-105
Molecular immunology 2025 Mar;179:94-105
N-Heterocyclic functionalized chalcone derivatives as anti-inflammatory agents for atopic dermatitis treatment by inhibiting JAK1/STAT3 signaling pathway.
Huang Z, Zhang X, Li J, Zhang L, Shen Y, Wang R, Zhang Y, Mao Z
Bioorganic chemistry 2025 Mar;156:108200
Bioorganic chemistry 2025 Mar;156:108200
SVCT2-targeted PET imaging agent for the evaluation of LN metastasis of thyroid cancer.
Peng L, Ge S, Yang T, Long Y, Nie H, Zhang Z, Wu R, Zhang D, Wen F, He Q, Liu J, Zhang X, Zha Z
Bioorganic chemistry 2025 Mar;156:108166
Bioorganic chemistry 2025 Mar;156:108166
Melatonin treatment increases skin microbiota-derived propionic acid to alleviate atopic dermatitis.
Yang L, Wang P, Gao T, Huang X, Lin Z, Sweren E, Li Y, Chen L, Alphonse MP, Zhang J, Wang G
The Journal of allergy and clinical immunology 2025 Mar;155(3):880-891.e9
The Journal of allergy and clinical immunology 2025 Mar;155(3):880-891.e9
circTUBD1-hnRNPK Regulates the Proliferation and Migration of LSCC by Targeting CCAR1.
Xu Y, Qiu S, Shen Z, Chen J
Cancer medicine 2025 Mar;14(6):e70834
Cancer medicine 2025 Mar;14(6):e70834
USP5 Promotes Head and Neck Squamous Cell Carcinoma Progression via mTOR Signaling Pathway.
Xiong N, Wang Y, Jiang J
Cancer medicine 2025 Mar;14(5):e70752
Cancer medicine 2025 Mar;14(5):e70752
Melanoma Cell Adhesion Molecule Plays a Pivotal Role in Proliferation, Migration, Tumor Immune Microenvironment, and Immunotherapy in Colorectal Cancer.
Zhou J, Liu J, Yu Y, Nie H, Hong Y, Ning Y, Yang C, Lai J, Wang H, Tang X, Wang F, Zhao Q
Cancer medicine 2025 Mar;14(5):e70740
Cancer medicine 2025 Mar;14(5):e70740
Anti-colorectal cancer actions of Glycyrrhiza uralensis Fisch. and its underlying mechanism via HPLC integration and network pharmacological approaches.
Duan H, Wang W, Shi Y, Wang L, Khan GJ, Luo M, Zhou J, Yang J, He C, Li F, Hu H, Zhai K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156370
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156370
Zn(2+) protects H9C2 cardiomyocytes by alleviating MAMs-associated apoptosis and calcium signaling dysregulation.
Guo J, Ma T, Wang B, Xing B, Huang L, Li X, Zheng H, He Y, Xi J
Cellular signalling 2025 Mar;127:111629
Cellular signalling 2025 Mar;127:111629
Mechanism underlying CDC20 affecting epithelial ovarian cancer biological behavior by regulating BAG6 ubiquitination.
Zhang X, Bi F, Yang Q
Cellular signalling 2025 Mar;127:111577
Cellular signalling 2025 Mar;127:111577
SGK1 mediates herpes simplex keratitis via the PI3K/SGK1/ Wnt signaling pathways.
Ye W, Tang S, Wang Y, Wang W, Liu Y, Xu H, Meng H, Lu Y, Huang Z, Ge Y
Cellular signalling 2025 Mar;127:111566
Cellular signalling 2025 Mar;127:111566
Circ-SPATA13 regulates the osteogenic differentiation of human periodontal ligament stem cells through the miR-485-5p_R + 1/BMP7 axis.
Xiao T, Shi Y, Ye Y, Wang J, Wang W, Yu H, Yan M, Yu J
Cellular signalling 2025 Mar;127:111561
Cellular signalling 2025 Mar;127:111561
Photothermal-Responsive Soluble Microneedle Patches for Meibomian Gland Dysfunction Therapy.
Yu F, Zhao X, Wang Q, Niu Y, Xiao P, Zhang J, Fei K, Huang Y, Liu L, Fang PH, Du X, Li W, He D, Zhang T, Li S, Yuan J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2413962
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2413962
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
Shi M, Li X, Guo Y, Zhang Y, Xu J, Yan L, Liu R, Wang H, Tang S, Zhao Y, Li Z, Feng Y, Ren D, Liu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
BPDE induces ferroptosis in hippocampal neurons through ACSL3 suppression.
He H, Ji T, Lyu Y, Tian F, Mu E, Mu S, Zheng J
Neurotoxicology 2025 Mar;107:11-21
Neurotoxicology 2025 Mar;107:11-21
Efficacy and mechanism of the XPO1 inhibitor selinexor combined with decitabine in T-cell lymphoblastic lymphoma.
Meng M, Feng X, Zhang Y, Gao Y, Han L, Li Z, Zhang X, Zhang M
Annals of hematology 2025 Mar;104(3):1747-1756
Annals of hematology 2025 Mar;104(3):1747-1756
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Jia S, Shi N, Lu M, Wang X, Qi Y, Wang X, Zhao J, Jiang D
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Piezo1 promotes intervertebral disc degeneration through the Ca(2+)/F-actin/Yap signaling axis.
Peng F, Sun M, Jing X, Chen F, Cao T, Li Z, Li T
Molecular medicine (Cambridge, Mass.) 2025 Mar 8;31(1):90
Molecular medicine (Cambridge, Mass.) 2025 Mar 8;31(1):90
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Liao M, Li C, Yang R, Li J, Wu K, Zhang J, Zhu Q, Shi Y, Zhang X
Cancer cell international 2025 Mar 8;25(1):85
Cancer cell international 2025 Mar 8;25(1):85
Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML.
Zhong Y, Zhang R, Lu L, Tan H, You Y, Mao Y, Yuan Y
Cell communication and signaling : CCS 2025 Mar 8;23(1):126
Cell communication and signaling : CCS 2025 Mar 8;23(1):126
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Zhang S, Gu M, Yin H, Pan S, Xie H, Chen W, Gul S, Zhao Y, Wang Z, Zheng W, You Y, You B
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Network pharmacology and in vivo study: Unraveling the therapeutic mechanisms of Panax ginseng in potentially treating ulcerative colitis.
Qin Y, Zhang RY, Zhang Y, Zhao YQ, Hao HF, Wang JP
World journal of gastroenterology 2025 Mar 7;31(9):100271
World journal of gastroenterology 2025 Mar 7;31(9):100271
Golgicide A induces pyroptosis of lung cancer stem cells by regulating dTGN formation via GOLPH3/MYO18A complex.
Zhang F, Zhang SH, Liu T, Xie GS, Deng SH, Zhang T, Wang XB, Yang YY, Chen ZX, Wu DM, Xu Y
Stem cell research & therapy 2025 Mar 7;16(1):121
Stem cell research & therapy 2025 Mar 7;16(1):121
Role of Galactosylceramide Metabolism in Satellite Glial Cell Dysfunction and Neuron-Glia Interactions in Painful Diabetic Peripheral Neuropathy.
Xu X, Zhang Y, Li S, Liao C, Yang X, Zhang W
Cells 2025 Mar 7;14(6)
Cells 2025 Mar 7;14(6)
The Effects of Sika Deer Antler Peptides on 3T3-L1 Preadipocytes and C57BL/6 Mice via Activating AMPK Signaling and Gut Microbiota.
Sun T, Hao Z, Meng F, Li X, Wang Y, Zhu H, Li Y, Ding Y
Molecules (Basel, Switzerland) 2025 Mar 6;30(5)
Molecules (Basel, Switzerland) 2025 Mar 6;30(5)
Dihydromyricetin Alleviated Acetaminophen-Induced Acute Kidney Injury via Nrf2-Dependent Anti-Oxidative and Anti-Inflammatory Effects.
Shi J, Peng X, Huang J, Zhang M, Wang Y
International journal of molecular sciences 2025 Mar 6;26(5)
International journal of molecular sciences 2025 Mar 6;26(5)
The shared mechanism of barrier dysfunction in ulcerative colitis and Alzheimer's disease: DDIT4/IL1β neutrophil extracellular traps drive macrophages-mediated phagocytosis.
Li SH, Huang QH, Yang QQ, Huang Q, Wang DX, Yang J, Huang SH, Zhang SY, Wang JM, Xie LS, Yu SG, Wu QF
International immunopharmacology 2025 Mar 6;149:114188
International immunopharmacology 2025 Mar 6;149:114188
L-Arabinose Alleviates Functional Constipation in Mice by Regulating Gut Microbiota and Metabolites.
Liu K, Dong H, Li X, Hu C, Cui F, Li S, Zhang X, Du Y, Yang P, Ji W, Sui W, Meng J
Foods (Basel, Switzerland) 2025 Mar 6;14(5)
Foods (Basel, Switzerland) 2025 Mar 6;14(5)
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF-κB/NLRP3 signaling pathway.
Liu W, Mao Y, Li H, Hu J, Gan T, Wang Y, Wang Y, Wang Z
European journal of pharmacology 2025 Mar 5;990:177292
European journal of pharmacology 2025 Mar 5;990:177292
circ_0000389 inhibits intervertebral disc degeneration by targeting the miR-346/KLF7 axis.
Liu C, Yu C, Duan Y, Li J, Chen X, Xu W, Qiu S
Acta biochimica et biophysica Sinica 2025 Mar 5;57(10):1636-1646
Acta biochimica et biophysica Sinica 2025 Mar 5;57(10):1636-1646
Perfluorobutanoic acid: A short-chain perfluoroalkyl substance exhibiting estrogenic effects through the estrogen-related receptor γ pathways.
Li F, Chen L, Shi S, Hong WJ, Li M, Guo LH
Journal of hazardous materials 2025 Mar 5;485:136947
Journal of hazardous materials 2025 Mar 5;485:136947
Reticulophagy promotes EMT-induced fibrosis in offspring's lung tissue after maternal exposure to carbon black nanoparticles during gestation by a m(5)C-dependent manner.
Du Z, Liu Q, Wang M, Gao Y, Li Q, Yang Y, Lu T, Bao L, Pang Y, Wang H, Niu Y, Zhang R
Journal of hazardous materials 2025 Mar 5;485:136873
Journal of hazardous materials 2025 Mar 5;485:136873
CD47 Contributes to the Proliferation of Breast Cancer.
Wang J, Wu X, Liu X, Xu Y
Frontiers in bioscience (Landmark edition) 2025 Mar 5;30(3):28210
Frontiers in bioscience (Landmark edition) 2025 Mar 5;30(3):28210
Analysis and identification of mitochondria-related genes associated with age-related hearing loss.
Ma T, Zeng X, Liu M, Xu S, Wang Y, Wu Q, Zhang T
BMC genomics 2025 Mar 5;26(1):218
BMC genomics 2025 Mar 5;26(1):218
The LncRNA lnc-POTEM-4:14 promotes HCC progression by interacting with FOXK1.
Peng B, Quan Z, Liang L, Liu M, Hu K, Chen S, Xie Q, Qin J, Chen J, Liao L, He S, Li Z
Scientific reports 2025 Mar 5;15(1):7672
Scientific reports 2025 Mar 5;15(1):7672
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
Yang Q, Chen Q, Zhang KB, Liu Y, Zheng JC, Hu DX, Luo J
Acta neuropathologica communications 2025 Mar 5;13(1):48
Acta neuropathologica communications 2025 Mar 5;13(1):48
KLF5 enhances CXCL12 transcription in adipose-derived stem cells to promote endothelial progenitor cells neovascularization and accelerate diabetic wound healing.
Xie Y, Ni X, Wan X, Xu N, Chen L, Lin C, Zheng X, Cai B, Lin Q, Ke R, Huang T, Hu X, Wang B, Shan X
Cellular & molecular biology letters 2025 Mar 4;30(1):24
Cellular & molecular biology letters 2025 Mar 4;30(1):24
The Non-Antibacterial Effects of Azithromycin and Other Macrolides on the Bronchial Epithelial Barrier and Cellular Differentiation.
Asbjarnarson A, Joelsson JP, Gardarsson FR, Sigurdsson S, Parnham MJ, Kricker JA, Gudjonsson T
International journal of molecular sciences 2025 Mar 4;26(5)
International journal of molecular sciences 2025 Mar 4;26(5)
α-Conotoxin TxIB Reversed Nicotine-Induced Locomotor Sensitization and Nicotine-Enhanced Dopaminergic Activity in Mice.
Xu W, Wang M, Li X, He R, Ding RB, Bao J, Zhangsun D, Luo S
Marine drugs 2025 Mar 4;23(3)
Marine drugs 2025 Mar 4;23(3)
Isorhamnetin ameliorates hyperuricemia by regulating uric acid metabolism and alleviates renal inflammation through the PI3K/AKT/NF-κB signaling pathway.
Kong X, Zhao L, Huang H, Kang Q, Lu J, Zhu J
Food & function 2025 Mar 31;16(7):2840-2856
Food & function 2025 Mar 31;16(7):2840-2856
Prognostic implications of alternative splicing events and key splicing factors in head and neck squamous cell carcinoma.
He S, Meng J, Liang C, Wang Y, Qin X, Huang L, Wang R, Huang W
Discover oncology 2025 Mar 31;16(1):430
Discover oncology 2025 Mar 31;16(1):430
Baicalin, Amoxicillin, and Probenecid Provide Protection in Mice Against Glaesserella parasuis Challenge.
Li J, Luo R, Fu Y, Liu S, Dong Q, Sun Y, Tian X, Zhu Y, Wang P, Guo L, Lu Q, Ye C, Fu S, Qiu Y
Biomolecules 2025 Mar 31;15(4)
Biomolecules 2025 Mar 31;15(4)
Arsenic enhances cervical cancer cell radiosensitivity by suppressing the DNA damage repair pathway.
Gao X, Liu G, Zhao Z, Tang Y, Hui H, Wang C, Li D, Ma Y, Sun Z, Zhou Y
Translational cancer research 2025 Mar 30;14(3):2078-2094
Translational cancer research 2025 Mar 30;14(3):2078-2094
Functionally conserved inner mitochondrial membrane proteins CCDC51 and Mdm33 demarcate a subset of fission events.
Edington AR, Connor OM, Love AC, Marlar-Pavey M, Friedman JR
The Journal of cell biology 2025 Mar 3;224(3)
The Journal of cell biology 2025 Mar 3;224(3)
(64)Cu Radiolabeled PDGFRβ-Targeting Affibody for PET Imaging in Pancreatic Cancer.
Li Z, Geng R, Zhan Y, Liu R, Li M, Ke N, Yang H, Lu X, Li L, Li S, Cai H
Molecular pharmaceutics 2025 Mar 3;22(3):1633-1640
Molecular pharmaceutics 2025 Mar 3;22(3):1633-1640
Application of a CYP1B1-Targeted NIR Probe for Breast Cancer Diagnosis, Surgical Navigation, and CYP1B1-Associated Chemotherapy Resistance Monitoring.
Wu Z, Shi T, Shao Q, Chen D, Gao P, Wang J, Xu T, Meng Q, Li S
Molecular pharmaceutics 2025 Mar 3;22(3):1507-1517
Molecular pharmaceutics 2025 Mar 3;22(3):1507-1517
Mechanistic Insights into Salvigenin for Glucocorticoid-Induced Femoral Head Osteonecrosis: A Network Pharmacology and Experimental Study.
Zhu Z, Zhong Y, He R, Zhong C, Chen J, Peng H
Biomedicines 2025 Mar 3;13(3)
Biomedicines 2025 Mar 3;13(3)
Niacin Ester Derivative of Brefeldin A as a Potential Dual-Target Arf1/BMX Inhibitor for Bladder Cancer.
Liu JY, Song YJ, Li PJ, Gao Y, Wei MY, Shao CL
Journal of natural products 2025 Mar 28;88(3):830-841
Journal of natural products 2025 Mar 28;88(3):830-841
Neurotransmitter 5-HT Further Promotes LL-37-Induced Rosacea-like Inflammation Through HTR3A.
Ma H, Liu J, Chen F, Zhou Y, Yang C, Zhao B
International journal of molecular sciences 2025 Mar 28;26(7)
International journal of molecular sciences 2025 Mar 28;26(7)
CSF3R-AS promotes hepatocellular carcinoma progression and sorafenib resistance through the CSF3R/JAK2/STAT3 positive feedback loop.
Feng Z, Gao Y, Cai C, Tan J, Liu P, Chen Y, Deng G, Ouyang Y, Liu X, Cao K, Zeng S, Han Y, Deng X, Shen H
Cell death & disease 2025 Mar 28;16(1):217
Cell death & disease 2025 Mar 28;16(1):217
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Lu Q, Liu J, Xiong Y, Jian J, Wang J, Chen Z, Wan S, Liu X, Wang L
Scientific reports 2025 Mar 28;15(1):10695
Scientific reports 2025 Mar 28;15(1):10695
FASN promotes lipid metabolism and progression in colorectal cancer via the SP1/PLA2G4B axis.
Liu X, Lu J, Ni X, He Y, Wang J, Deng Z, Zhang G, Shi T, Chen W
Cell death discovery 2025 Mar 28;11(1):122
Cell death discovery 2025 Mar 28;11(1):122
Aggregation of the constitutively active K296E rhodopsin mutant contributes to retinal degeneration.
Vasudevan S, Prakash V, Park PS
bioRxiv : the preprint server for biology 2025 Mar 28;
bioRxiv : the preprint server for biology 2025 Mar 28;
Targeted Degradation of Bromodomain-Containing Protein 4 Enabled by Reactive Oxygen Species-Activatable NanoPROTACs as an Efficient Strategy to Reverse Liver Fibrosis in Chronic Liver Injury.
Bi T, Liang P, Zhao Q, Wu J, Zhou Y, Xu Y, Fan X, Yang G, Sun Q, Ren W, Yang Y, Liu Z
Journal of medicinal chemistry 2025 Mar 27;68(6):6328-6338
Journal of medicinal chemistry 2025 Mar 27;68(6):6328-6338
Construction and evaluation of a prognostic model based on the expression of the metabolism-related signatures in patients with osteosarcoma.
Wu T, Wu X
BMC musculoskeletal disorders 2025 Mar 27;26(1):303
BMC musculoskeletal disorders 2025 Mar 27;26(1):303
IL-33/ST2 signalling promotes tumor growth by regulating polarization of alternatively activated macrophages.
Liu L, Luo H, Xie Y, Wang Y, Ren S, Sun H, Li D
Cancer biology & medicine 2025 Mar 27;22(4):376-95
Cancer biology & medicine 2025 Mar 27;22(4):376-95
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
Wang Y, Huang J, Song Z, Zhang S, Guo H, Leng Q, Fang N, Ji S, Yang J
Biology direct 2025 Mar 27;20(1):37
Biology direct 2025 Mar 27;20(1):37
A self-assembling peptide-based hydrogel containing NF-κB inhibitors and NGF for peripheral nerve injury repair.
Su H, Ye Q, Wang D, Liu A, Wang Y, Zhang Y, Weng L
Biofabrication 2025 Mar 27;17(2)
Biofabrication 2025 Mar 27;17(2)
Mechanism of action of Danlou tablets affecting MAFLD via KEAP1-mediated oxeiptosis.
Zhu J, Song N, Wang J, Wang Q, Cao Y, Zhang M, Sun X, Jia L
Journal of ethnopharmacology 2025 Mar 26;344:119521
Journal of ethnopharmacology 2025 Mar 26;344:119521
Oxytocin-loaded hydrogel promotes cartilage regeneration and regulates microenvironment.
Wang T, Zhao X, Li J, Yin C, Jiang B, Xie J, Wang B, Wang Y, Cao Z, Yao Q, Zheng S, Sui J, Zhu K
Biofabrication 2025 Mar 26;17(2)
Biofabrication 2025 Mar 26;17(2)
Reprogramming Macrophage Phenotype Using a Reactive Oxygen Species-Responsive Liposome Delivery System for Inflammation Microenvironment Remodeling and Osteoarthritis Treatment.
Lai P, Ma Y, Sang W, Zhou Q, Chen H, Wang C, Yin J, Wang T, Zhu L, Zhou X, He C, Ma J
ACS applied materials & interfaces 2025 Mar 26;17(12):17932-17947
ACS applied materials & interfaces 2025 Mar 26;17(12):17932-17947
LincRNA-ASAO promotes dental pulp repair through interacting with PTBP1 to increase ALPL alternative splicing.
Fang F, Guo X, Liu S, Dang L, Chen Z, Yang Y, Chen L, Lin J, Qiu W, Chen Z, Wu B
Stem cell research & therapy 2025 Mar 26;16(1):149
Stem cell research & therapy 2025 Mar 26;16(1):149
GPER1/ACACB are potential target genes associated with intracranial aneurysm and vascular endothelial cell senescence.
Zeng L, Lu X, Huang Y, Tu Q, He Y, Fang Z, Nie S, Huang Y, Yu M, Min X, Zhang C, Yu J, Zhang L
Neurosurgical review 2025 Mar 25;48(1):321
Neurosurgical review 2025 Mar 25;48(1):321
A KIF1C-CNBP motor-adaptor complex for trafficking mRNAs to cell protrusions.
Moissoglu K, Wang T, Gasparski AN, Stueland M, Paine EL, Jenkins LM, Mili S
Cell reports 2025 Mar 25;44(3):115346
Cell reports 2025 Mar 25;44(3):115346
Amniotic fluid-derived exosomal miR-146a-5p ameliorates preeclampsia phenotypes by inhibiting HIF-1α/FLT-1 expression.
Lin J, Huang X, Zhang J, Yang W, Sun F, Huang B, Lu W, Wang X
Placenta 2025 Mar 25;162:35-44
Placenta 2025 Mar 25;162:35-44
XIAP promotes metastasis of bladder cancer cells by ubiquitylating YTHDC1.
Sun N, Wang S, Liu J, Zhang P, Chang Y, Li H, Zhao K, Liu Y, Huang M, Hu Y, Lin Z, Lu Y, Jiang G, Chen W, Huang C, Jin H
Cell death & disease 2025 Mar 25;16(1):205
Cell death & disease 2025 Mar 25;16(1):205
Effect of Benzyl Isothiocyanate on Anaplastic Thyroid Cancer Evaluated by Network Pharmacology Combined with Experiments.
Ma C, Zhang Q, Wang Y, Li D, Zhang H, Jia Q, Zheng W, Tan J, Xu K, Yang L, Meng Z
ACS omega 2025 Mar 25;10(11):11063-11076
ACS omega 2025 Mar 25;10(11):11063-11076
Berberine Exerts Neuroprotective Effects in Alzheimer's Disease by Switching Microglia M1/M2 Polarization Through PI3K-AKT Signaling.
Hu Y, Zhang P, Wang X
Physiological research 2025 Mar 24;74(1):129-140
Physiological research 2025 Mar 24;74(1):129-140
Compositionally unique mitochondria in filopodia support cellular migration.
Marlar-Pavey M, Tapias-Gomez D, Mettlen M, Friedman JR
Current biology : CB 2025 Mar 24;35(6):1227-1241.e6
Current biology : CB 2025 Mar 24;35(6):1227-1241.e6
DMC-BH derivative DMC-GF inhibits the growth of glioma stem cells by targeting the TRIM33/SLC25A1/mitochondrial oxidative phosphorylation pathway.
Shi L, Fei X, Huang J, He B, Sun Z, Sun G
Journal of translational medicine 2025 Mar 24;23(1):363
Journal of translational medicine 2025 Mar 24;23(1):363
Prognostic and immunological implications of protein kinases in gastric cancer: a focus on hub gene ABL2 and its impact on the polarization of M2 macrophages.
Chen D, Huang J, Yang A, Xiong Z
Biology direct 2025 Mar 24;20(1):35
Biology direct 2025 Mar 24;20(1):35
Rewired m6A methylation of promoter antisense RNAs in Alzheimer's disease regulates global gene transcription in the 3D nucleome.
Hu B, Shi Y, Xiong F, Chen YT, Zhu X, Carrillo E, Wen X, Drolet N, Rajpurohit C, Xu X, Lee DF, Soto C, Zhong S, Jayaraman V, Zheng H, Li W
bioRxiv : the preprint server for biology 2025 Mar 24;
bioRxiv : the preprint server for biology 2025 Mar 24;
ASPM mediates nuclear entrapment of FOXM1 via liquid-liquid phase separation to promote progression of hepatocarcinoma.
Jiang X, Liu J, Wang K, Sun J, Yin H, Jiang Y, Liu Y, Wang N, Ding X, Gao P, Li L, Zhang X, Li J, Zhang R
Genome biology 2025 Mar 23;26(1):68
Genome biology 2025 Mar 23;26(1):68
MDA5 protein mediating persistent ER stress/unfolded protein response contributes to endothelial-mesenchymal-transition of lung microvascular endothelial cell in dermatomyositis.
Zhao LQ, Yang XQ, Niu Q, Feng X, Zhang HD, Ye SY, Jiang LJ, Yu F, Ye H, Ma WL
Cell communication and signaling : CCS 2025 Mar 23;23(1):149
Cell communication and signaling : CCS 2025 Mar 23;23(1):149
miR-378d suppresses gastric cancer metastasis by targeting METTL4 to inhibit epithelial-mesenchymal transition.
Xing D, Bao J, He J, Gao H, Xue W, Chen J, Li J
Journal of molecular histology 2025 Mar 22;56(2):116
Journal of molecular histology 2025 Mar 22;56(2):116
Downregulated Expression of miR-200c-3p in Plasma Exosome as a Potential Biomarker in Takayasu's Arteritis.
Du L, Fang C, Huang B, Zeng X, Li J, Tian X
International journal of molecular sciences 2025 Mar 22;26(7)
International journal of molecular sciences 2025 Mar 22;26(7)
Radiotherapy-derived engineered stem cell exosomes improve anti-glioma immunotherapy by promoting the formation of tertiary lymphoid structure and improve the release of type I interferon.
Li M, Lu L, Bao Q, Zhou M, Nie B, Liu Y, Shu K, Lei T, Zhu M
Journal of nanobiotechnology 2025 Mar 22;23(1):239
Journal of nanobiotechnology 2025 Mar 22;23(1):239
Identification of RNA processing factor LSM5 as a new adverse biomarker in nasopharyngeal carcinoma.
Lin T, Deng L, Liu S, Chen Y, Tang Y, Zhou F, Gong G, He Y
Scientific reports 2025 Mar 22;15(1):9901
Scientific reports 2025 Mar 22;15(1):9901
The m6A reader HNRNPC is a key regulator in DSS-induced colitis by modulating macrophage phenotype.
Fang X, Zhang Y, Ke Z, Zhang Y, Lin Y, Huang Y, Zhou J, Su H, Xu J, Liu Y
iScience 2025 Mar 21;28(3):111812
iScience 2025 Mar 21;28(3):111812
Single-molecule m(6)A detection empowered by endogenous labeling unveils complexities across RNA isoforms.
Guo W, Ren Z, Huang X, Liu J, Shao J, Ma X, Wei C, Cun Y, He J, Zhang J, Wu Z, Guo Y, Zhang Z, Feng Z, He J, Wang J
Molecular cell 2025 Mar 20;85(6):1233-1246.e7
Molecular cell 2025 Mar 20;85(6):1233-1246.e7
Estrogen via GPER downregulated HIF-1a and MIF expression, attenuated cardiac arrhythmias, and myocardial inflammation during hypobaric hypoxia.
Wowui PI, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Kanoseh AWL, Tao L, Chulu D, Yalley SK, Shaheen S, Sun H
Molecular medicine (Cambridge, Mass.) 2025 Mar 20;31(1):107
Molecular medicine (Cambridge, Mass.) 2025 Mar 20;31(1):107
BMAL1 attenuates intervertebral disc degeneration by activating the SIRT1/PGC-1α pathway: evidence from vitro studies.
Sang P, Ma Y, Zhang X, Chen B, He F, Shen N, Zhao J
Scientific reports 2025 Mar 20;15(1):9651
Scientific reports 2025 Mar 20;15(1):9651
Precision Quantification and Rational Regulation of Protein Expression with Bicistronic Cassette for Efficient Biotin Production.
Li S, Zhou X, Chen Y, Li G, Deng Y
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6854-6866
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6854-6866
NEK2 promotes the progression of osteosarcoma through the AKT/p-AKT pathway and interacts with FoxM1.
Tan X, Liang X, Feng Y, Xie M, Zhong K, Luo W, Wang Y, Yin Y, Cai Y
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):120
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):120
FKBP51 is Involved in Epileptic Seizure by Regulating PSD95 in a PTZ-Induced Epileptic Mouse Model.
Chen L, Cui W, Qin J, Zhu M, Zhang H, Yang J, Xu Z, Huang H
Journal of integrative neuroscience 2025 Mar 19;24(3):25710
Journal of integrative neuroscience 2025 Mar 19;24(3):25710
Chitosan Oligosaccharides Prevent Alcohol-Induced Liver Disease by Attenuating Inflammation and Oxidative Stress.
Liu Y, Sun J, Yan Q, Wen B, Bai Y, Che Q, Cao H, Guo J, Su Z
Marine drugs 2025 Mar 19;23(3)
Marine drugs 2025 Mar 19;23(3)
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer.
Guo Y, Zhang Z, Dong L, Shi X, Li X, Luo M, Fu Y, Gao Y
Journal of translational medicine 2025 Mar 18;23(1):347
Journal of translational medicine 2025 Mar 18;23(1):347
Oroxylin A reverses SHP-2 oxidative inactivation in GPVI signaling to suppress platelet activation and thrombus formation.
Chen Y, Lin Y, Hong J, Wang J, Li B, Liu Z, Ma Y, Sun X, Wang S, Li M, Wu M, Fu D, Li J, Wang M, Hu L
Thrombosis journal 2025 Mar 18;23(1):26
Thrombosis journal 2025 Mar 18;23(1):26
Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis.
Liu Q, Lu X, Deng Y, Zhang H, Wei R, Li H, Feng Y, Wei J, Ma F, Zhang Y, Zou X
Nature communications 2025 Mar 18;16(1):2676
Nature communications 2025 Mar 18;16(1):2676
Human umbilical cord mesenchymal stem cell-derived exosomes promote osteogenesis in glucocorticoid-induced osteoporosis through PI3K/AKT signaling pathway-mediated ferroptosis inhibition.
Zhao ZM, Ding JM, Li Y, Wang DC, Kuang MJ
Stem cells translational medicine 2025 Mar 18;14(3)
Stem cells translational medicine 2025 Mar 18;14(3)
Trans-Golgi network tethering factors regulate TBK1 trafficking and promote the STING-IFN-I pathway.
Wang J, Niu S, Hu X, Li T, Liu S, Tu Y, Shang Z, Zhao L, Xu P, Lin J, Chen L, Billadeau DD, Jia D
Cell discovery 2025 Mar 18;11(1):23
Cell discovery 2025 Mar 18;11(1):23
S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis.
Xu W, Li Y, Wan S, Zhang B, Wei D, Zhang H, Jin X, Xie B, Guan C, Song X
Free radical biology & medicine 2025 Mar 16;230:112-126
Free radical biology & medicine 2025 Mar 16;230:112-126
TRIM22 inhibits the metastasis of colorectal cancer through facilitating β-Catenin degradation.
Hu H, Li W, Ma P, Song J, Zhang X, Ruan L, Zhang J, Zheng Y
Experimental cell research 2025 Mar 15;446(2):114473
Experimental cell research 2025 Mar 15;446(2):114473
MiR-222-3p loaded stem cell nanovesicles repair myocardial ischemia damage via inhibiting mitochondrial oxidative stress.
Liu M, Wang L, Liu Z, Liu D, Li T, Ding L, Zeng S, Wang Z, Wang J, Zhang F, Zhang J, Zhang L, Li M, Liu G, Wang X, Zheng M
Life sciences 2025 Mar 15;365:123447
Life sciences 2025 Mar 15;365:123447
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation.
Liang L, Shen Z, Zhang K, Zhang C, Dong L, Shi R, Hua L, Zhao R, Feng N
Life sciences 2025 Mar 15;365:123442
Life sciences 2025 Mar 15;365:123442
Noradrenaline Synergistically Enhances Porphyromonas gingivalis LPS and OMV-Induced Interleukin-1β Production in BV-2 Microglia Through Differential Mechanisms.
Muramoto S, Shimizu S, Shirakawa S, Ikeda H, Miyamoto S, Jo M, Takemori U, Morimoto C, Wu Z, Tozaki-Saitoh H, Oda K, Inoue E, Nonaka S, Nakanishi H
International journal of molecular sciences 2025 Mar 15;26(6)
International journal of molecular sciences 2025 Mar 15;26(6)
Engineered macrophage membrane-coated nanoparticles attenuate calcium oxalate nephrocalcinosis-induced kidney injury by reducing oxidative stress and pyroptosis.
Ba X, Ye T, He Y, Tong Y, Shang H, Wu J, Deng W, Zhong Z, Yang X, Wang K, Xie Y, Jiang K, Guo X, Tang K
Acta biomaterialia 2025 Mar 15;195:479-495
Acta biomaterialia 2025 Mar 15;195:479-495
Transmembrane protein 176B promotes epithelial-mesenchymal transition in colorectal cancer through inflammasome inhibition.
Qian W, Xu CY, Hong W, Li ZM, Xu DG
World journal of gastrointestinal oncology 2025 Mar 15;17(3):97673
World journal of gastrointestinal oncology 2025 Mar 15;17(3):97673
An advanced cytosine base editor enabled the generation of cattle with a stop codon in the β-lactoglobulin gene.
Ding Q, Cui Z, Shi Q, Zhang Y, He N, Guo R, Tian Y, Cao S, Zhong J, Wang H
Transgenic research 2025 Mar 14;34(1):14
Transgenic research 2025 Mar 14;34(1):14
ERBB4 as a therapeutic target in aortic dissection: Implications for cell-based therapies in vascular regeneration.
Shi Y, Meng J, Zhang S, Yang S, Liu G, Wu Z, Shen C, Shi C
Biomolecules & biomedicine 2025 Mar 14;25(10):2324-2334
Biomolecules & biomedicine 2025 Mar 14;25(10):2324-2334
Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo.
Lu Y, Yan Z, Sun J, Wang C, Xu L, Lyu X, Wang X, Lou J, Huang H, Meng L, Zhao Y
Journal of medicinal chemistry 2025 Mar 13;68(5):5616-5640
Journal of medicinal chemistry 2025 Mar 13;68(5):5616-5640
Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction.
Li XJ, Zhang MC, Li X, Guan LL, Liang YR, Hao EJ, Wang Y, Guo HM
Journal of medicinal chemistry 2025 Mar 13;68(5):5573-5596
Journal of medicinal chemistry 2025 Mar 13;68(5):5573-5596
Evaluation of anti-hyperuricemic and nephroprotective activities and discovery of new XOD inhibitors of Morus alba L. root bark.
Wang YA, Guo X, Zhang MQ, Sun ST, Ren QD, Wang MX, Wang LN, Farag MA, Sun JY, Liu C, Chen YY
Journal of ethnopharmacology 2025 Mar 13;343:119476
Journal of ethnopharmacology 2025 Mar 13;343:119476
Network pharmacology integrated with experimental validation reveals the mechanism of Xanthii Fructus against allergic rhinitis via JAK2/STAT3/HIF-1α signaling pathway.
Xiong J, Wu Y, Luo L, Shen X, Zeng Y, Meng X, Zhang H
Journal of ethnopharmacology 2025 Mar 13;343:119461
Journal of ethnopharmacology 2025 Mar 13;343:119461
Huachansu Injection induces ferroptosis in multiple myeloma through NRF2/HO-1 signaling pathway.
Yang J, Wang F, Hu Z, Liu X, Zhang W, Li C, Wang W, Reaila J, Zhang X, Zhu G, Tian F, Chen B, Zhu X
Journal of ethnopharmacology 2025 Mar 13;343:119454
Journal of ethnopharmacology 2025 Mar 13;343:119454
Inhibition of stemness and PD-L1 expression by Pien Tze Huang enhances T cell-mediated killing of colorectal cancer.
Lu Q, Zhang Z, Liu S, Wang J, Yang X, Yan T, Yang Y, Chen X, Li L, Liu G, Du J, Cao Z
Journal of ethnopharmacology 2025 Mar 13;343:119447
Journal of ethnopharmacology 2025 Mar 13;343:119447
Identification of TAP2 as a novel immune target in human cancers: insights from integrated bioinformatics and experimental approaches.
Yang L, Gui J, Sheng Y, Liu J, Wang C, Fang Z, Huang L, Tu Z, Zhu X, Huang K
European journal of medical research 2025 Mar 13;30(1):163
European journal of medical research 2025 Mar 13;30(1):163
Circ-AARS plays an important role during the odontogenic differentiation of dental pulp stem cells by modulating miR-24-3p/KLF6 expression.
Sui M, Lyu J, Zhou J, Liao Q, Xiao Z, Jin M, Tao J
Stem cell research & therapy 2025 Mar 13;16(1):137
Stem cell research & therapy 2025 Mar 13;16(1):137
Identification of ETFDH gene c. 487 + 2 T > A pathogenic variant and mechanisms for polycystic kidney in neonatal onset MADD.
Zhang B, Zhang D, Sun F, Si X, Luan M, He R
Orphanet journal of rare diseases 2025 Mar 12;20(1):121
Orphanet journal of rare diseases 2025 Mar 12;20(1):121
LST1 expression correlates with immune infiltration and predicts poor prognosis in acute myeloid leukemia.
Xu H, Chen D, Lu J, Wang L, Chen F, Zhong L
Discover oncology 2025 Mar 12;16(1):305
Discover oncology 2025 Mar 12;16(1):305
The feedback loop between miR-222-3p and ZEB1 harnesses metastasis in renal cell carcinoma.
Wang F, Li L, Sun X, Cai X, Wang J, Luo H, Wang Y, Ni D, Wang D
Cell death discovery 2025 Mar 12;11(1):97
Cell death discovery 2025 Mar 12;11(1):97
Decoding CKD-induced muscle atrophy through the critical role of lncRNA GAS5 and pyroptosis.
Huang R, Tang X, Liu S, Sun L
Molecular therapy. Nucleic acids 2025 Mar 11;36(1):102451
Molecular therapy. Nucleic acids 2025 Mar 11;36(1):102451
Gengnianchun formula ameliorates insulin resistance-induced diminished ovarian reserve via the estrogen signaling pathway: evidence from network pharmacology and experimental validation.
Rao Y, Li J, Xu T, Gao L, Wang W
Journal of ovarian research 2025 Mar 11;18(1):51
Journal of ovarian research 2025 Mar 11;18(1):51
HDAC11 in ovarian granulosa cells coordinates LH in the maturation of oocytes in Tan sheep.
Shi J, Lv D, Xu Y, Wang X, Qi Z, Yan Y, Wang J, Song H, Yang H, Jin L, Yang Z, Yang X, Kang X, Liu X, Zhang Z, Wang C
Acta biochimica et biophysica Sinica 2025 Mar 10;57(10):1660-1669
Acta biochimica et biophysica Sinica 2025 Mar 10;57(10):1660-1669
Efficacy and mechanism of inhibition of the GPR30-PI3K pathway by 4-phenylbutyric acid in the treatment of intrahepatic cholestasis of pregnancy.
Liao E, Liu QQ, Huang XM, Shao Y
Journal of molecular histology 2025 Mar 10;56(2):102
Journal of molecular histology 2025 Mar 10;56(2):102
Magnetically triggered thermoelectric heterojunctions with an efficient magnetic-thermo-electric energy cascade conversion for synergistic cancer therapy.
Yuan X, Kang Y, Li R, Niu G, Shi J, Yang Y, Fan Y, Ye J, Han J, Pei Z, Zhang Z, Ji X
Nature communications 2025 Mar 10;16(1):2369
Nature communications 2025 Mar 10;16(1):2369
Berberine-inspired ionizable lipid for self-structure stabilization and brain targeting delivery of nucleic acid therapeutics.
Bian X, Guo Q, Yau LF, Yang L, Wang X, Zhao S, Wu S, Qin X, Jiang ZH, Li C
Nature communications 2025 Mar 10;16(1):2368
Nature communications 2025 Mar 10;16(1):2368
Mitochondria are positioned at dendritic branch induction sites, a process requiring rhotekin2 and syndapin I.
Tröger J, Dahlhaus R, Bayrhammer A, Koch D, Kessels MM, Qualmann B
Nature communications 2025 Mar 10;16(1):2353
Nature communications 2025 Mar 10;16(1):2353
Protective effects of Rosa roxburghii Tratt. extract against UVB-induced inflammaging through inhibiting the IL-17 pathway.
Zhang S, Chen Y, Qu L
Scientific reports 2025 Mar 10;15(1):8260
Scientific reports 2025 Mar 10;15(1):8260
The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision.
Gao J, Wang J, Liu S, Song J, Zhang C, Liu B, Wu K
eLife 2025 Mar 10;13
eLife 2025 Mar 10;13
Manganese-Based Nanozyme Alleviates Acute Kidney Injury via Nrf2/HO-1 and PI3K/Akt/NF-κB Signaling Pathways.
Zhang Y, Wang H, Liu K, Sun R, Wang Y, Guo J, Zhou W, Zheng H, Qi Y
ACS biomaterials science & engineering 2025 Mar 10;11(3):1751-1764
ACS biomaterials science & engineering 2025 Mar 10;11(3):1751-1764
GRASP55 regulates sorting and maturation of the lysosomal enzyme β-hexosaminidase A.
Akaaboune SR, Javed A, Bui S, Wierenga A, Wang Y
Molecular biology of the cell 2025 Mar 1;36(3):ar30
Molecular biology of the cell 2025 Mar 1;36(3):ar30
Bisphenol A exposure enhances proliferation and tumorigenesis of papillary thyroid carcinoma through ROS generation and activation of NOX4 signaling pathways.
Wang Y, Su X, Wang Q, Zhang L, Yu Y, Zhao Y, Liu Z
Ecotoxicology and environmental safety 2025 Mar 1;292:117946
Ecotoxicology and environmental safety 2025 Mar 1;292:117946
Bisphenol F induces spermatogenic cell ferroptosis via FTO-mediated m6A regulation of FTH1.
Zhou SM, Shi Y, Li JY, Wang N, Zeng Y, Chen HQ, Tan YP, Deng SW, Liu QQ, Huang XQ, Wang YQ, Zhou ZY, Liu WB
Free radical biology & medicine 2025 Mar 1;229:364-373
Free radical biology & medicine 2025 Mar 1;229:364-373
Baicalin reduced vandetanib induced myocardial injury by regulating redox balance and NLRP3 inflammasome pathway.
Wang F, Li J, Zhang Z, Huang G, Zhang X, Liu Q, Xiao W, Liu F, Sun J, Liu Y, Ma Y, Zhuang R, Du Y, Wang X, Gao C, Gu X
Tissue & cell 2025 Jun;94:102795
Tissue & cell 2025 Jun;94:102795
HIF-3α Facilitates the Proliferation and Migration in Pancreatic Cancer by Inhibiting Autophagy Through Downregulating TP53INP2.
Zhou X, Ling Y, Huang L, Yang F, Zhang Y, Lan Y
Cell biochemistry and biophysics 2025 Jun;83(2):2139-2150
Cell biochemistry and biophysics 2025 Jun;83(2):2139-2150
TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling.
Yang Y, Liu S, Xiao X
Cell biochemistry and biophysics 2025 Jun;83(2):2101-2113
Cell biochemistry and biophysics 2025 Jun;83(2):2101-2113
Protein S-glutathionylation confers cellular resistance to ferroptosis induced by glutathione depletion.
Ju Y, Zhang Y, Tian X, Zhu N, Zheng Y, Qiao Y, Yang T, Niu B, Li X, Yu L, Liu Z, Wu Y, Zhi Y, Dong Y, Xu Q, Yang X, Wang X, Wang X, Deng H, Mao Y, Li X
Redox biology 2025 Jun;83:103660
Redox biology 2025 Jun;83:103660
Cth/Mpst double ablation results in early onset fatty liver disease in lean mice.
Katsouda A, Markou M, Valakos D, Theodorou I, Papapetropoulos A
Redox biology 2025 Jun;83:103641
Redox biology 2025 Jun;83:103641
Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances.
Zhong H, Jiang M, Yuan K, Sheng F, Xu X, Cui Y, Sun X, Tan W
Animal models and experimental medicine 2025 Jun;8(6):977-989
Animal models and experimental medicine 2025 Jun;8(6):977-989
Picroside II regulates the YY1/TGFβ1 axis by inhibiting osteoblast ferroptosis to alleviate symptoms of postmenopausal osteoporosis.
Wang H, Qian J
Cytotechnology 2025 Jun;77(3):114
Cytotechnology 2025 Jun;77(3):114
Catalpol inhibits Hedgehog signaling pathway to suppress proliferation and promote lipid accumulation in rat meibomian gland epithelial cells.
Liu Z, Zhang R, Lai J
Cytotechnology 2025 Jun;77(3):105
Cytotechnology 2025 Jun;77(3):105
Fluoride induces hepatointestinal damage and vitamin B(2) mitigation by regulating IL-17A and Bifidobacterium in ileum.
Liang C, Zhuang C, Cheng C, Bai J, Wu Y, Li X, Yang J, Li B, Fu W, Zhu Q, Lv J, Tan Y, Kumar Manthari R, Zhao Y, Wang J, Zhang J
Journal of advanced research 2025 Jun;72:671-684
Journal of advanced research 2025 Jun;72:671-684
ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment.
Dong X, Wang H, Cai J, Wang Y, Chai D, Sun Z, Chen J, Li M, Xiao T, Shan C, Zhang JV, Yu M
Journal of advanced research 2025 Jun;72:197-212
Journal of advanced research 2025 Jun;72:197-212
Olaparib Combined with Anti-PD1 Enhances Immunotherapy of Gastric Cancer Via NF-κB/c-Myc/PD-L1 Signaling.
Zheng W, Ge Z, Wu Q, Wan H, Sun J, Nai Y, Lv C
Digestive diseases and sciences 2025 Jun;70(6):2032-2042
Digestive diseases and sciences 2025 Jun;70(6):2032-2042
TREML2 enhances sensitivity of acute myeloid leukemia cells to chemotherapy by inhibiting the NF-κB/CXCL10 pathway.
Zhang X, Yan S, Zhang X, Huang D, Zhou J, Song X, Hao Y, Wang X, Yan J
Blood science (Baltimore, Md.) 2025 Jun;7(2):e00223
Blood science (Baltimore, Md.) 2025 Jun;7(2):e00223
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
Ou W, Li X, Tang K, Ding L, Sun T, Li Q, Li T
Science China. Life sciences 2025 Jun;68(6):1689-1702
Science China. Life sciences 2025 Jun;68(6):1689-1702
Linc00239 Facilitates the Progress of Clear Cell Renal Cell Carcinoma via the miR-204-5p/RAB22A Axis.
Cheng C, Lin S, Zhu A, Hong Z, Shi Z, Deng H, Zhang G
Molecular biotechnology 2025 Jun;67(6):2357-2366
Molecular biotechnology 2025 Jun;67(6):2357-2366
TSPAN31 Activates Fatty Acid Metabolism and PI3K/AKT Pathway to Promote Tumor Progression in Breast Cancer.
Luo W, Sun Y, Cao L
Molecular carcinogenesis 2025 Jun;64(6):1078-1089
Molecular carcinogenesis 2025 Jun;64(6):1078-1089
Identification and Validation of Basement Membrane Related LncRNA Signatures as a Novel Prognostic Model for Hepatocellular Carcinoma.
Liu X, Lv C, Zheng J, Xiao J, He N, Du J, Yang X, Gu H
Biochemical genetics 2025 Jun;63(3):2100-2119
Biochemical genetics 2025 Jun;63(3):2100-2119
Knockdown TNF family prognosis index crucial gene PDE4B promoted PANoptosis of ovarian carcinoma cell:Based in vitro and in vivo experiments.
Yu Q, Wang Y, Fu T, Han D, Wang L, Zhao L, Xu Y
Translational oncology 2025 Jun;56:102333
Translational oncology 2025 Jun;56:102333
The phosphatase CTDSPL2 promotes proliferation, invasion, metastasis and regorafenib resistance in osteosarcoma.
Bai G, Zhao S, Zhao M, Chen L, Chen W
Journal of bone oncology 2025 Jun;52:100684
Journal of bone oncology 2025 Jun;52:100684
Upregulation of YY1 in M2 macrophages promotes secretion of exosomes containing hsa-circ-0000326 via super-enhancers to facilitate prostate cancer progression.
Guan H, Tao H, Luo J, Wan L, Hu H, Chen L, Wen Z, Tao Y, Chen S, Gu M
Molecular and cellular biochemistry 2025 Jun;480(6):3873-3888
Molecular and cellular biochemistry 2025 Jun;480(6):3873-3888
Exogenous hydrogen sulfide improves non-alcoholic fatty liver disease by inhibiting endoplasmic reticulum stress/NLRP3 inflammasome pathway.
Fu X, Zhang Q, Chen Y, Li Y, Wang H
Molecular and cellular biochemistry 2025 Jun;480(6):3813-3839
Molecular and cellular biochemistry 2025 Jun;480(6):3813-3839
Functional Upregulation of TRPM3 Channels Contributes to Acute Pancreatitis-associated Pain and Inflammation.
Liu L, Liu H, Zhao M, Wen J, Liu J, Lv G, Xiao Z, Wang W, Zu S, Sun W, Zhang X, Gong L
Inflammation 2025 Jun;48(3):1015-1027
Inflammation 2025 Jun;48(3):1015-1027
ADAM10-mediated β-klotho degradation: a key to FGF21 resistance in senescent vascular endothelial cells.
Huang Y, Zhang Y, Yang N, Qian Z, Fang Z, Zeng L, Huang Y, Li H, Luo M, Yan J, Ruan L, Zhang C, Zhang L
GeroScience 2025 Jun;47(3):5089-5110
GeroScience 2025 Jun;47(3):5089-5110
Bardoxolone displays potent activity against triple negative breast cancer by inhibiting the TRIP13/STAT3 circuit.
Deng JH, Li HY, Liu ZY, Liang JP, Ren Y, Zeng YY, Wang YL, Mao XL
Acta pharmacologica Sinica 2025 Jun;46(6):1733-1741
Acta pharmacologica Sinica 2025 Jun;46(6):1733-1741
Androgen Receptor Mediates Dopamine Agonist Resistance by Regulating Intracellular Reactive Oxygen Species in Prolactin-Secreting Pituitary Adenoma.
Xu L, Lei Z, Wang Q, Jiang Q, Xing B, Li X, Guo X, Wang Z, Li S, Huang Y, Lei T
Antioxidants & redox signaling 2025 Jun;42(16-18):954-972
Antioxidants & redox signaling 2025 Jun;42(16-18):954-972
Identification of GABBR2 as a diagnostic marker and its association with Aβ in Alzheimer's disease.
Li H, Fan Y, Chen C, Xu Y, Wang X, Liu W
Biochemistry and biophysics reports 2025 Jun;42:102035
Biochemistry and biophysics reports 2025 Jun;42:102035
The effects of FOXC2-gene-manipulated human periodontal ligament stem cells on bone regeneration of craniofacial bone defect.
Chen Y, Zhang X, Tang Y, Yang Y, Wu Z, Lai W, Long H
Dental materials : official publication of the Academy of Dental Materials 2025 Jun;41(6):708-720
Dental materials : official publication of the Academy of Dental Materials 2025 Jun;41(6):708-720
S1PR2 Mediates Smooth Muscle Cell Proliferation and Endothelial Cell Permeability via Akt/mTOR and RhoA/ROCK1 in Atherosclerosis.
Ouyang J, Long H, Chen S, Xiang H, Shu Z, Wang X, Zhang J, Liu H, Tang B, Xiao J, Liu Q, Zhan Z, Chen R, Lu H
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70351
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70351
JNK kinase promotes inflammatory responses by inducing the expression of the inflammatory amplifier TREM1 during influenza a virus infection.
Chen N, Jin J, Qiao B, Gao Z, Tian Y, Ping J
Virus research 2025 Jun;356:199577
Virus research 2025 Jun;356:199577
The role of LncRNA-MANCR induced by HIF-1α drive the malignant progression of pancreatic cancer by targeting miRNA-494/SIRT1 signaling axis under hypoxic conditions.
Jin Y, Hu H, Tian Y, Xu H, Yu Q, Cheng L, Guo X, Wang Z, Huang X, Wang X, Wang G
Cancer gene therapy 2025 Jun;32(6):633-648
Cancer gene therapy 2025 Jun;32(6):633-648
Decreased FTO Expression Promotes Ovarian Granulosa Cells Aging.
Ying J, Zhang X, Sun X, Meng Q
Reproductive sciences (Thousand Oaks, Calif.) 2025 Jun;32(6):1987-1997
Reproductive sciences (Thousand Oaks, Calif.) 2025 Jun;32(6):1987-1997
Hydrogel-mediated mitochondrial reprogramming for inducing cell death: a novel approach to overcoming gemcitabine resistance in pancreatic ductal adenocarcinoma.
Zhao Q, Liu S, Bi T, Wang T, Chen L, Huang J, Yang X, Dai X, Liu Z, Sun Q
Materials today. Bio 2025 Jun;32:101940
Materials today. Bio 2025 Jun;32:101940
A pH/MMP-9 smart dual-responsive liposome GBE@LP co-delivers and controls the release of GB1107/BMS1166/Enzalutamide for liver cancer immunotherapy.
Lu S, Zhang C, Wu H, Wang J, Wang J, Zhao L, Ren T, Li G
Materials today. Bio 2025 Jun;32:101801
Materials today. Bio 2025 Jun;32:101801
Bufotalin loaded biomimetic nanodrug for combined chemo/photodynamic therapy of cancer.
Chen S, Fan J, Xie Q, Qin Y, Xie H, Xiao C, Wang W, Liu B
Materials today. Bio 2025 Jun;32:101684
Materials today. Bio 2025 Jun;32:101684
Harnessing engineered exosomes as METTL3 carriers: Enhancing osteogenesis and suppressing lipogenesis in bone marrow mesenchymal stem cells for postmenopausal osteoporosis treatment.
Li T, Zhao J, Yuan J, Ding R, Yang G, Cao J, Zhao X, Liu J, Liu Y, Xu P, Deng J, Miao X, Cheng X
Materials today. Bio 2025 Jun;32:101648
Materials today. Bio 2025 Jun;32:101648
Targeting m(6)A demethylase FTO to heal diabetic wounds with ROS-scavenging nanocolloidal hydrogels.
Zheng X, Deng S, Li Y, Luo Z, Gan Z, Zheng Z, Xu R, Xiao S, Cai Y, Meng J, Li L, Li C, Xue X, Dai W, Qin S, Wang M, Zeng K, Xiao Z, Xia L
Biomaterials 2025 Jun;317:123065
Biomaterials 2025 Jun;317:123065
Sanghuangporus vaninii polysaccharides alleviates the effects of chlorpyrifos exposure on mouse liver: role of the gut- liver axis.
Liu J, Sun L, Tang Y, Li J, Chen W, Geng J, Zong Y, He Z, Du R
International journal of biological macromolecules 2025 Jun;315(Pt 1):144504
International journal of biological macromolecules 2025 Jun;315(Pt 1):144504
MicroRNA-9-3p inhibits endothelial pyroptosis in atherosclerosis by targeting the PTEN/AKT axis.
Wu Y, Ma Q, Meng X, Sun Q, Wang Z, Zhang W
International journal of biological macromolecules 2025 Jun;315(Pt 1):144289
International journal of biological macromolecules 2025 Jun;315(Pt 1):144289
Enhancing BMSC chondrogenesis with a dynamic viscoelastic hyaluronan hydrogel loaded with kartogenin for cartilage repair.
Li G, Ni R, Shi Z, Mao H, Luo Y, Cao X, Zhang C, Liu Y, Jin Z, Chen J, Fu J, Zhang H, Zhu Y
International journal of biological macromolecules 2025 Jun;312:144042
International journal of biological macromolecules 2025 Jun;312:144042
miR-301a-5p regulated IKKβ/NF-κB axis and macrophage polarization to accelerate skin wound healing.
Li Y, Fu Z, Deng C, Qian J, Wang Z, Lu Y, Zhang S, Liu G, Wen J, Chen Y, Jiang J, Liu X, Zheng X, Shen X, Su W, Yang M, Tang J, Wang Y, Meng B, Yang X
International journal of biological macromolecules 2025 Jun;311(Pt 4):143995
International journal of biological macromolecules 2025 Jun;311(Pt 4):143995
P4HB, a novel succinated protein, is essential for fumarate-induced cancer metastasis.
Song X, Rao H, Huang C, Huang M, Ma Y, Xin J, Hou J, Hu Z, He L, Pan F, Yang L, Guo Z
International journal of biological macromolecules 2025 Jun;311(Pt 3):143885
International journal of biological macromolecules 2025 Jun;311(Pt 3):143885
Sacituzumab tirumotecan in advanced non-small-cell lung cancer with or without EGFR mutations: phase 1/2 and phase 2 trials.
Zhao S, Cheng Y, Wang Q, Li X, Liao J, Rodon J, Meng X, Luo Y, Chen Z, Wang W, Yi T, Li Y, Yin Y, Xu H, Yu G, Mi Y, Fan Y, Wainberg ZA, Wang X, Su C, Yu Q, Lai S, Sun L, Zhuang W, Wang X, Yang J, Li Y, Ge J, Li J, Zhang L, Fang W
Nature medicine 2025 Jun;31(6):1976-1986
Nature medicine 2025 Jun;31(6):1976-1986
α‑ketoglutarate protects against septic cardiomyopathy by improving mitochondrial mitophagy and fission.
Wu W, Ma Q, Li BT, Shi S, Guan GC, Wang JK, Xue BY, Liu ZW
Molecular medicine reports 2025 Jun;31(6)
Molecular medicine reports 2025 Jun;31(6)
Role and mechanism of mitochondrial dysfunction‑related gene biomarkers in the progression of type 2 diabetes mellitus.
Liu M, Qiao H
Molecular medicine reports 2025 Jun;31(6)
Molecular medicine reports 2025 Jun;31(6)
Human transmembrane protein 68 links triacylglycerol synthesis to membrane lipid homeostasis.
Zeng F, Heier C, Yu Q, Pang H, Huang F, Zhao Z, Chang P
The FEBS journal 2025 Jun;292(11):2935-2952
The FEBS journal 2025 Jun;292(11):2935-2952
A potent dual inhibitor targeting COX-2 and HDAC of acute myeloid leukemia cells.
Qin X, Wang X, Yang C, Wang F, Fang T, Gu D, Guo Q, Meng Q, Liu W, Yang L
Molecular diversity 2025 Jun;29(3):2433-2444
Molecular diversity 2025 Jun;29(3):2433-2444
DPP7 Promotes Colorectal Cancer Progression Through GPX4-Dependent Suppression of Disulfidptosis and Immune Evasion.
Li R, Wang X, Liu J, Cai Z, Li Z, Tao Q, Wang C
Journal of cellular and molecular medicine 2025 Jun;29(12):e70660
Journal of cellular and molecular medicine 2025 Jun;29(12):e70660
LncRNA SNHG14 Regulated by ZNF460 Promotes Gastric Cancer Progression and Metastasis by Targeting the miR-206/FNDC3A Axis.
Liu B, Lu T, Zhang G, Dong X, Yu M, Cai H
Journal of cellular and molecular medicine 2025 Jun;29(11):e70652
Journal of cellular and molecular medicine 2025 Jun;29(11):e70652
Effects of Adalimumab on Mitochondria of Psoriatic Mesenchymal Stem Cells.
Di Vincenzo M, Campanati A, Cannelonga G, Diotallevi F, Cerqueni G, Marani A, Marchi S, Orciani M
Journal of cellular and molecular medicine 2025 Jun;29(11):e70642
Journal of cellular and molecular medicine 2025 Jun;29(11):e70642
Tripterygium wilfordii polyglycoside tablets attenuated the progression of hepatocellular carcinoma by targeting IL-6 and downstream signaling pathways in a multi-target manner.
Ren PY, Zhang JY, Zhao L, Sun XJ
Journal of Asian natural products research 2025 Jun;27(6):929-949
Journal of Asian natural products research 2025 Jun;27(6):929-949
Histone deacetylase 6 inhibition attenuates pathological cardiac hypertrophy by promoting autophagy through MAP1LC3B ubiquitination.
Yao J, Sun X, Chen Y, Xu X, Feng J, Zhang M, Liu X, Shi X
The Journal of pathology 2025 Jun;266(2):217-229
The Journal of pathology 2025 Jun;266(2):217-229
A Golgi apparatus-related signature predicts the immune microenvironment and prognosis of gastric cancer.
Wu C, Sun L, Zhu W, Huang C, Zhu Z, Liu Z
Genes and immunity 2025 Jun;26(3):242-252
Genes and immunity 2025 Jun;26(3):242-252
AMPK phosphorylation of K(Ca)2.3 alleviates angiotensin II-induced endothelial dysfunction.
Pang ZD, Wang Y, Han MZ, She G, Sun X, Bai RY, Lai BC, Zhang Y, Du XJ, Shyy JY, Deng XL
Biochemical pharmacology 2025 Jun;236:116880
Biochemical pharmacology 2025 Jun;236:116880
TIMELESS as a prognostic biomarker and therapeutic target in gastric cancer.
Meng X, Sun Q, Liu Z, Cao S, Xu C, Di L, Wu Y, Zhang W
Journal, genetic engineering & biotechnology 2025 Jun;23(2):100504
Journal, genetic engineering & biotechnology 2025 Jun;23(2):100504
Inhibition of SFRP1 by microRNA‑206‑3p may be the underlying cause of osteosarcopenia.
Yu C, Lu Z, Du Y, Lv Y, Fang J, Zhao Y, Peng Z, Lu S
Biomedical reports 2025 Jun;22(6):103
Biomedical reports 2025 Jun;22(6):103
Targeting overexpressed HSPA8 by halofuginone suppresses aberrant proliferation and invasion of rheumatoid arthritis fibroblast-like synoviocytes.
Tang Y, Wu H, Yan P, Yue Z, Hu Z, Liao X, Wang Y, Lin Y, Li L, Cai X
Pharmacological research 2025 Jun;216:107762
Pharmacological research 2025 Jun;216:107762
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
Wu Y, Duan Z, Qu L, Liu Y, Ma X, Fan D
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
Circovirus Rep evades immune restriction by disrupting cGAS oligomerization and phase separation.
Yin H, Zhao Z, Yuan Y, Li M, Chai L, Qu W, Ya Y, Wang H, Li X
PLoS pathogens 2025 Jun;21(6):e1013244
PLoS pathogens 2025 Jun;21(6):e1013244
The Erk1/2-EGR1 signaling pathway is involved in lipopolysaccharide-induced transforming growth factor-beta 1 expression in mouse macrophages.
Zhao W, Wang H, Dai C, Li B, Fu Y, Cheng J, Li H
Microbial pathogenesis 2025 Jun;203:107453
Microbial pathogenesis 2025 Jun;203:107453
Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition.
Qin X, Lu F, Wan J, Teng X, Jin S, Xiao L, Xue H, Guo Q, Tian D, Wu Y
Journal of molecular and cellular cardiology 2025 Jun;203:10-21
Journal of molecular and cellular cardiology 2025 Jun;203:10-21
Angio-associated migratory cell protein promotes colorectal cancer progression by enhancing phosphoglycerate kinase 1 phosphorylation.
Zhang W, Shi Q, Liu Q, Zhang H, Xia J, Zhang X
Journal of cell communication and signaling 2025 Jun;19(2):e70023
Journal of cell communication and signaling 2025 Jun;19(2):e70023
Rbm39 ameliorates metabolic dysfunction-associated steatotic liver disease by regulating Apob and Fabp4.
Zhuang C, Cui F, Chen J, He D, Sun T, Wang P
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167815
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167815
Aloe Vera flowers extracts inhibit melanogenesis via activating PI3K/Akt signaling pathway: Network pharmacology and experimental validation.
Li J, Zou W, Li M, Yan Y, Yu Y, Li X, Ma YL
Fitoterapia 2025 Jun;183:106530
Fitoterapia 2025 Jun;183:106530
Anti-tumor effectiveness of a novel bispecific antibody that blocks both PD-L1 and LAG-3.
Zhang C, Liu J, Sun M, Gu T, Meng X, Zhu S, Zhang Y, Wang L, Chen Y, Zhang D, Wu Y
Molecular immunology 2025 Jun;182:30-40
Molecular immunology 2025 Jun;182:30-40
PLK1 Downregulation Attenuates ET-1-Induced Cardiomyocyte Hypertrophy by Suppressing the ERK1/2 Pathway.
Ding J, Yang A, Zhou L, Zhang F, Zhou H, Zhang Y, Wang Y, Liu Y, Liang D, Liu Y, Wu Y
Journal of cardiovascular translational research 2025 Jun;18(3):586-598
Journal of cardiovascular translational research 2025 Jun;18(3):586-598
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes.
Hou X, Hu G, Wang H, Yang Y, Sun Q, Bai X
Journal of cardiovascular translational research 2025 Jun;18(3):574-585
Journal of cardiovascular translational research 2025 Jun;18(3):574-585
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
Xi X, Ding X, Wang Q, Liu N, Wang B, Wang G, Zhong W, Lu Y
Clinical and translational medicine 2025 Jun;15(6):e70359
Clinical and translational medicine 2025 Jun;15(6):e70359
MLKL‒OPTN axis regulates herpesvirus-induced neurological sequelae.
Bhattacharya I, Kadam R, Yadavalli T, Patil CD, Borase H, Volety I, Kalinin S, Feinstein DL, Tseng HC, Shukla D
Clinical and translational medicine 2025 Jun;15(6):e70353
Clinical and translational medicine 2025 Jun;15(6):e70353
Pitavastatin-loaded procyanidins self-assembled nanoparticles alleviate advanced atherosclerosis via modulating macrophage efferocytosis and cholesterol efflux.
Wu Y, Zhou H, Liu H, Hu J, Sun Y, Yan W, Tong C, Kong Y, Liu B
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3305-3320
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3305-3320
Kaempferol combats the osteogenic differentiation damage of periodontal ligament stem cells in periodontitis via regulating EphrinB2-mediated PI3K/Akt and P38 pathways.
Cao J, Li Y, Si M, Ma S, Li M, Shi A, Liu J, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156733
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156733
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Zhang J, Tan B, Wu H, Han T, Fang D, Cai H, Hu B, Kang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Tanshinone IIA promotes ferroptosis in cutaneous melanoma via STAT1-mediated upregulation of PTGS2 expression.
Chen S, Li P, Shi K, Tang S, Zhang W, Peng C, Li T, Xie H, Liu C, Zhou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156702
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156702
An Energy Metabolism Nanoblocker for Cutting Tumor Cell Respiration and Inhibiting Mitochondrial Hijacking from Cytotoxic T Lymphocyte.
Leng X, Yang Y, Jiang T, Zheng J, Zhang L, Huang J, Xu H, Fang M, Li X, Wang Z, Ge M, Lin H
Advanced healthcare materials 2025 Jun;14(16):e2405174
Advanced healthcare materials 2025 Jun;14(16):e2405174
Artificial intelligence-driven microRNA signature for early detection of gastric cancer: discovery and clinical functional exploration.
Lu J, Chen Y, Liu X, Wang J, He Y, Shi T, Chen W, Yan W
British journal of cancer 2025 Jun;132(10):957-972
British journal of cancer 2025 Jun;132(10):957-972
Study on the Mechanism of Fisetin Exerting Anti-Liver Cancer Effects by Regulating Neutrophil Extracellular Traps.
Gao J, Song Y, Luo Z, Su Z, Fu C, Gao A, Zhao J, Liu L, Teng X, Xu J
Food science & nutrition 2025 Jun;13(6):e70309
Food science & nutrition 2025 Jun;13(6):e70309
ULBP2 promotes progression of head and neck squamous cell carcinoma by modulating MAPK signaling pathway.
Xu W, Liu S, Yang W
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102204
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102204
Long non-coding RNA ANRIL/p65 negative feedback loop protects intestinal barrier function in inflammatory bowel disease.
Yu K, Peng H, Zhang Z, Ye L, Zhan K, Li C, Gan L, Lin Y, Wang Y, Song Y, Mei Z, Liao S, Guo J, Lv L
Non-coding RNA research 2025 Jun;12:167-179
Non-coding RNA research 2025 Jun;12:167-179
Ginsenoside Rg1 improves autophagy dysfunction to ameliorate Alzheimer's disease via targeting FGR proto-oncogene.
Quan Q, Ma X, Feng J, Li W, Li X
Neuropeptides 2025 Jun;111:102514
Neuropeptides 2025 Jun;111:102514
Triglyceride-lowering effect of rice protein due to the regulation of fatty acid uptake and transport of triglyceride in rats fed normal/oil-enriched diets.
Liu B, Wang Z, Liang M, Yang L
Food chemistry. Molecular sciences 2025 Jun;10:100253
Food chemistry. Molecular sciences 2025 Jun;10:100253
Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H(2)O(2)-induced injury in PC12 cells.
Wang Q, Zhu C, Song Z, Qiao Y, Hu Y, Hu L, Li S, Wang R
BMC complementary medicine and therapies 2025 Jun 9;25(1):208
BMC complementary medicine and therapies 2025 Jun 9;25(1):208
OTUB1-SLC7A11 Axis Mediates 4-Octyl Itaconate Protection Against Acetaminophen-Induced Ferroptotic Liver Injury.
Hu Z, Li Y, Xu D, Meng H, Liu W, Xu Q, Yao B, Wang J
Antioxidants (Basel, Switzerland) 2025 Jun 9;14(6)
Antioxidants (Basel, Switzerland) 2025 Jun 9;14(6)
α9 Nicotinic Acetylcholine Receptor Promotes Tumor Proliferation and Suppresses Ferroptosis in Triple-Negative Breast Cancer.
Feng X, Tian Y, Guo X, Lei JH, Yu J, Zheng C, Chen M, Ding RB, Kwok HF, Luo S, Bao J
Biomolecules 2025 Jun 8;15(6)
Biomolecules 2025 Jun 8;15(6)
Role and mechanism of lncRNA ZEB1-AS1 endogenous competition for miR-365a-3p targeting NRF2 in ferroptosis in articular chondrocytes.
Zhang R, Liu Y, Zang H, He A, Mao Y, Liu W
Journal of molecular histology 2025 Jun 7;56(3):190
Journal of molecular histology 2025 Jun 7;56(3):190
An ultra-high-performance tandem mass spectrometry method to quantify tryptophan metabolites in aqueous humor of primary angle-closure glaucoma patients.
Fu X, Guo W, Cheng Y, Li L
Journal of chromatography. A 2025 Jun 7;1750:465939
Journal of chromatography. A 2025 Jun 7;1750:465939
Acevaltrate overcomes myeloma resistance to bortezomib via pyroptosis by promoting BAX translocalization to mitochondria.
Wang Y, Cui Y, Liu Z, Liu L, Huang Z, Wang Q, Mao X
European journal of pharmacology 2025 Jun 5;996:177572
European journal of pharmacology 2025 Jun 5;996:177572
Mitochondrial oxidative stress inhibited Sirt3/Foxo3/PPARα pathway and aggravated copper and zinc co-deficiency-induced hepatic lipotoxicity in a fish model.
Zhong CC, Zhang X, Pantopoulos K, Song CC, Yang H, Wei XL, Luo Z
Cellular and molecular life sciences : CMLS 2025 Jun 5;82(1):226
Cellular and molecular life sciences : CMLS 2025 Jun 5;82(1):226
EHDPP impairs intestinal microbiota homeostasis and induces placental injury through choline mediated gut-placenta axis.
Du T, Lei S, Huang Z, Liu X, Jiang Z, Lu M, Zhou Y, Yuan J, Song W, Gu H, Li J
Journal of hazardous materials 2025 Jun 5;489:137573
Journal of hazardous materials 2025 Jun 5;489:137573
Exploring the immunomodulatory mechanism of total glucosides of paeony on Sjögren's syndrome dry eye disease based on the "gut-eye axis" pathway.
Fu T, Lu W, Wu D, Xu L, Wu G
International ophthalmology 2025 Jun 5;45(1):230
International ophthalmology 2025 Jun 5;45(1):230
Dehydrodiisoeugenol targets NOD2 exerting dual effects against colitis and colorectal cancer: a double-edged sword.
Yi F, Chen N, Zhao M, Gu Z, Yuan Y, Tang X, Liu F
Molecular medicine (Cambridge, Mass.) 2025 Jun 5;31(1):221
Molecular medicine (Cambridge, Mass.) 2025 Jun 5;31(1):221
Discovery of potent and selective CDK2 inhibitors with high safety and favorable bioavailability for the treatment of cancer.
Chen W, Zhuang X, Chen Y, Shen L, Yang H, Wang M, Pan G, Tan J, Pan X, Feng S, Yuan K, Zhang XY, Yang P
European journal of medicinal chemistry 2025 Jun 5;290:117503
European journal of medicinal chemistry 2025 Jun 5;290:117503
Molecular adaptations in MMP genes support lung elasticity and diving adaptations in cetaceans.
Zhang Y, Lv W, Yan W, Guo B, Yang G, Ren W
BMC genomics 2025 Jun 5;26(1):562
BMC genomics 2025 Jun 5;26(1):562
β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1.
Li Y, Fang J, Ding Y, Zhang X, Liu Y, Qiu W, Xu H, Kang Y, Chen J, Gao Y, Zhao YG, Yang P, Wang B, Tian W, Chen Y, Bi W, Zhang P
Nature communications 2025 Jun 5;16(1):5227
Nature communications 2025 Jun 5;16(1):5227
Inhibition of CTSC contributes to psoriasis inflammation and keratinocyte hyperproliferation by NF-κB signaling pathway.
He Y, Huang M, Wang Y, Cai X, Xiao F
International immunopharmacology 2025 Jun 5;157:114808
International immunopharmacology 2025 Jun 5;157:114808
TGF-β1 induces autophagy and mediates the effect on macrophages differentiation in primary liver cancer.
Liu C, Li M, Liu L, Xu Q, Zheng L, Wu C, Ren J, Zhang T, Wang H, Lin Z
International immunopharmacology 2025 Jun 5;157:114799
International immunopharmacology 2025 Jun 5;157:114799
The JAK1/STAT3 pathway mediates the effects of SERPINH1 on glioma EMT.
Wang S, Sun Z, Wang C, Zhang A, Zhang C, Hou S, Lin N, Li Q
International immunopharmacology 2025 Jun 5;157:114731
International immunopharmacology 2025 Jun 5;157:114731
FTY720 alleviates D-GalN/LPS-induced acute liver failure by regulating the JNK/MAPK pathway.
Guan J, Wu F, Wu S, Ren Y, Wang J, Zhu H
International immunopharmacology 2025 Jun 5;157:114726
International immunopharmacology 2025 Jun 5;157:114726
Ergosterol Protects Canine MDCK Cells from Gentamicin-Induced Damage by Modulating Autophagy and Apoptosis.
Qin Z, Xie L, Wang Y, Zhang N, Bi H, Song M, Xu C
Metabolites 2025 Jun 5;15(6)
Metabolites 2025 Jun 5;15(6)
Atlas of lysine propionylation of human right atrium and ALDH6A1-NADH pathway in new-onset atrial fibrillation after coronary surgery.
Zhang Y, Chen HX, Hou HT, Liu YQ, Chen Z, Yang Q, He GW
Communications biology 2025 Jun 4;8(1):858
Communications biology 2025 Jun 4;8(1):858
Elucidation of Molecular Mechanisms of Sulfated Oligoguluronic Acid on Mitigating Intestinal Inflammation and Enhancing Epithelial Barrier Function.
Bi D, Huang J, Zhu N, Yao L, Wu Y, Peng Y, Chen G, Zhu B, Xu X
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13605-13617
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13605-13617
Pro-Arrhythmic Effect of Chronic Stress-Associated Humoral Factors in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Su S, Sun J, Qiu S, Wu W, Zhang J, Wang Y, Shi C, Xu Y
Biology 2025 Jun 4;14(6)
Biology 2025 Jun 4;14(6)
Nervonic acid mitigates IMQ-triggered psoriasis in mice via inhibiting Th17/γδT17 cell invasion and modulating the gut microbiota.
Yang Z, Geng X, Zhang S, Gao J, Ji F, Han Y, Cui Z, Wang X, Guo S, Yan D, Zhao T, Ren F, Li X, Dong J, Tian Z, Yin Z, Song X
Journal of leukocyte biology 2025 Jun 4;117(6)
Journal of leukocyte biology 2025 Jun 4;117(6)
Alpha-1 antitrypsin modulates neutrophil phenotype and function: implications for inflammatory regulation.
Oshins R, Patel I, Khartabil L, Katikaneni DS, Scindia Y, Khodayari N
Journal of leukocyte biology 2025 Jun 4;117(6)
Journal of leukocyte biology 2025 Jun 4;117(6)
Fibril fuzzy coat is important for α-synuclein pathological transmission activity.
Han Y, Li J, Xia W, Li Q, Sun Z, Zeng W, Hu Y, Luk KC, Liu C, Xiang S, He Z
Neuron 2025 Jun 4;113(11):1723-1740.e7
Neuron 2025 Jun 4;113(11):1723-1740.e7
NR5A1 Deficiency Leads to Decidualization Dysregulation of Stromal Cells and Recurrent Spontaneous Abortion During Early Pregnancy.
Dai J, Jiang H, Liu D, Dong Z, Hu L, He F, Yu T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70752
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70752
Characterization of T cell proliferation-associated hepatocellular carcinoma subtypes, predictive signatures, and candidate targets.
Yang Q, Liu L, Zhu Y, Shen Z, Xu Y, Zhang M, Chen X
Journal of gastrointestinal oncology 2025 Jun 30;16(3):1127-1143
Journal of gastrointestinal oncology 2025 Jun 30;16(3):1127-1143
Theaflavin inhibits the malignant phenotype of human anaplastic thyroid cancer 8305C cells by regulating lipid metabolism via PI3K/AKT signaling.
Cai S, Zhang L, Liu T, Wang B, Yan S, Wang S, Yu J, Wu S, Lin S, Zhao W
Translational cancer research 2025 Jun 30;14(6):3758-3771
Translational cancer research 2025 Jun 30;14(6):3758-3771
Transcriptional regulation of solute carrier family 6 member 9 gene.
Kirii M, Yoshida Y, Takashima S, Uchio-Yamada K, Oh-Hashi K
Molecular biology reports 2025 Jun 3;52(1):540
Molecular biology reports 2025 Jun 3;52(1):540
PSMB10 maintains the stemness of chemotherapeutic drug-resistant leukemia cells by inhibiting senescence and cytotoxic T lymphocyte-mediated killing in a ubiquitinated degradation manner.
Ma X, Li Y, Wang D, Niu J, Li Q, Chen Y, Wang M, Wen J, Liao C, Wang N, Zhang X, Chang J, Yang J, Li L, Zou J, Peng D, Liu L
Journal of experimental & clinical cancer research : CR 2025 Jun 3;44(1):170
Journal of experimental & clinical cancer research : CR 2025 Jun 3;44(1):170
PRMT1 inhibition enhances the cardioprotective effect of adipose-derived mesenchymal stem cells against myocardial infarction through RUNX1.
Du D, Wang T, Sun Y, Zhang Y, Zhang B, Shao J, Yang M, Huang C, Zuo S, Wu N
Stem cell research & therapy 2025 Jun 3;16(1):279
Stem cell research & therapy 2025 Jun 3;16(1):279
Tumor-intrinsic TTLL12 drives resistance to cancer immunotherapy via modulating myeloid-derived suppressor cells.
Chen DW, Cheng YK, Li PS, Wu XJ, Huang XX, Long JH, Xiong Z, Chen C, Ye SB, Lan P
Journal for immunotherapy of cancer 2025 Jun 3;13(6)
Journal for immunotherapy of cancer 2025 Jun 3;13(6)
E3 ubiquitin-protein ligase CBL inhibits non-small cell lung cancer progression via ubiquitination and degradation of KDR.
Tu Z, Shen Y, Li H
Cell division 2025 Jun 28;20(1):17
Cell division 2025 Jun 28;20(1):17
Transcriptomic and Functional Validation Reveals PAQR3/P6-55 as Potential Therapeutic Targets in Colon Cancer.
You X, Gai Y, Wang Z, Wang Y, Ye J, Cao Y, Zhang H, Zhang Z, Feng Y
Biology 2025 Jun 27;14(7)
Biology 2025 Jun 27;14(7)
Saroglitazar Ameliorates Pulmonary Fibrosis Progression in Mice by Suppressing NF-κB Activation and Attenuating Macrophage M1 Polarization.
Zhang Y, Lin J, Han X, Chen X
Medicina (Kaunas, Lithuania) 2025 Jun 26;61(7)
Medicina (Kaunas, Lithuania) 2025 Jun 26;61(7)
Proteomics based discovery of Salvia miltiorrhiza Bunge treating Parkinson's disease through the PINK1/Parkin pathway.
Xu D, ShenTu C, Zong C, Fu W, Ling J, Shao P, Liu X, Chen Y, Xu T
Journal of ethnopharmacology 2025 Jun 26;350:120079
Journal of ethnopharmacology 2025 Jun 26;350:120079
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Pu Y, Ren W, Gan Z, Wang S, Peng M, Yue R, Huang R
Journal of ethnopharmacology 2025 Jun 26;350:119989
Journal of ethnopharmacology 2025 Jun 26;350:119989
Reduced NRF2/Mfn2 activity promotes endoplasmic reticulum stress and senescence in adipose-derived mesenchymal stem cells in hypertrophic obese mice.
Fang J
World journal of stem cells 2025 Jun 26;17(6):104367
World journal of stem cells 2025 Jun 26;17(6):104367
Inflammation-induced TET3/mir-3942 axis impedes the proliferation and invasion ability of trophoblast cells through destabilization of SERPINE1 in preeclampsia.
Deng X, Zuo Q, Liu Y, Li M, Wu L, Jiang J, Rahman J, Sagnelli M, Zhang T, Sun L, Xu Y
Placenta 2025 Jun 26;167:193-203
Placenta 2025 Jun 26;167:193-203
Integrated transcriptome analysis and combinatorial machine learning to construct a homeostatic model of acetylation for ccRCC and validate the key gene GCNT4.
Zhu B, Mo Z, Bao Y, Gan X, Wang L
Cancer cell international 2025 Jun 25;25(1):236
Cancer cell international 2025 Jun 25;25(1):236
Endoplasmic reticulum-anchored nonstructural proteins drive human astrovirus replication organelle formation.
Bengert B, Mehri S, Holliday M, Lennemann NJ
bioRxiv : the preprint server for biology 2025 Jun 25;
bioRxiv : the preprint server for biology 2025 Jun 25;
Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders.
Solo KJ, Zhang Y, Bharathi SS, Zhang BB, Richert AC, Schmidt AV, Basu S, Land CV, D'Annibale O, Wood TC, Vockley J, Goetzman ES
bioRxiv : the preprint server for biology 2025 Jun 25;
bioRxiv : the preprint server for biology 2025 Jun 25;
UBE3C promotes pancreatic ductal adenocarcinoma progression by catalysing p53 ubiquitination.
Shi Y, Wang J, Cheng Q, Wu S, Qin X, Yang Z
Molecular biology reports 2025 Jun 24;52(1):633
Molecular biology reports 2025 Jun 24;52(1):633
Bright-light treatment ameliorates motor and non-motor deficits through distinct visual circuits in a mouse model of Parkinson's disease.
Huang X, Wang S, Chen Z, Qu W, Song L, Hu Z, Xi Y, Yang Y, Hong WH, Lin S, So KF, Li Y, Huang L, Tao Q, Ren C
Cell reports 2025 Jun 24;44(6):115865
Cell reports 2025 Jun 24;44(6):115865
ENPP1 governs the metabolic regulation of effector T cells in autoimmunity by detecting cytosolic mitochondrial DNA.
Ji H, Jiang W, Zhang J, Liu M, Su D, Lei J, Li L, Zheng M, Liu T, Liu Z, Cao Q, Xu L, Xiong S, Wen Z
Cell reports 2025 Jun 24;44(6):115851
Cell reports 2025 Jun 24;44(6):115851
Expression Dynamics and Estrogen Response of Estrogen Receptors in Duolang Sheep During Puberty.
Zhu L, Shahbaz GM, Sun H, Zhang J, Li W, Gu R, Xing F
Genes 2025 Jun 24;16(7)
Genes 2025 Jun 24;16(7)
5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy activation.
Xu N, Huang J, Wang Y, Liu Y, Jiang Y, Zhou W, Sheng J, Zhang L
Acta biochimica et biophysica Sinica 2025 Jun 23;58(2):290-302
Acta biochimica et biophysica Sinica 2025 Jun 23;58(2):290-302
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
Dong J, Wu Y, Che J, He Z, Zhang J
Cancer & metabolism 2025 Jun 23;13(1):33
Cancer & metabolism 2025 Jun 23;13(1):33
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer.
Zhang Y, Yang E, Zhang X, Zhang Z, Huang G, Tang B, Chen C, Lai L, Pei Z, Zhang Y, Wang Z
Journal of cancer research and clinical oncology 2025 Jun 21;151(6):194
Journal of cancer research and clinical oncology 2025 Jun 21;151(6):194
Gut microbiota from voluntary exercised mice protects the intestinal barrier by inhibiting neutrophil extracellular trap formation.
Zhu B, Wu H, Zhang H, Song Q, Xiao Y, Yu B
iScience 2025 Jun 20;28(6):112763
iScience 2025 Jun 20;28(6):112763
Taurine ameliorates blood pressure and vascular function in patients with type 2 diabetes: Randomized, double-blind, placebo-controlled trial.
Li Y, Wang Q, Liu Y, Li Q, Xia W, Lin S, Yang Q, Scholze A, Zhao Z, He H, Zhang H, Yan Z, Tepel M, Mu H, Zhu Z, Liu D
iScience 2025 Jun 20;28(6):112719
iScience 2025 Jun 20;28(6):112719
Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway.
Qiu XF, He CM, Zeng YM, Deng XL, Liang GL, Zhong MX, Zou M, Xiong XJ, Zhang JD, Ye Y, Niu Q, Chen XL
iScience 2025 Jun 20;28(6):112634
iScience 2025 Jun 20;28(6):112634
UHRF1 phase separation mediates stable inheritance of DNA methylation and promotes the proliferation of prostate cancer cells.
Li Z, Wang Y, Yu Z, Luo Y, Zhao Y, Xue E, Zhan J, Lu H, Sun F
Cell communication and signaling : CCS 2025 Jun 20;23(1):297
Cell communication and signaling : CCS 2025 Jun 20;23(1):297
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Zheng X, Cao Z, Wang M, Yuan R, Han Y, Li A, Wang X
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Liang H, Liang Y, Wu L, Lin L, Yao Y, Deng J, Xu J, Li H, Gao F, Xing W, Yu M, Jia X, Wei M, Li C, Zheng G
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
DNA Damage Response Regulation Alleviates Neuroinflammation in a Mouse Model of α-Synucleinopathy.
Khan S, Singh H, Xiao J, Khan MM
Biomolecules 2025 Jun 20;15(7)
Biomolecules 2025 Jun 20;15(7)
Fatty Acid Desaturase 1 Knockdown Promotes Wound Healing and Functional Recovery of the Corneal Epithelium in Diabetes.
Zhao Y, Dong Y, Zheng Q, Zhao Y, Ni Y, Qiu P, Chen C, Xu M, Hong C, Shen T
Investigative ophthalmology & visual science 2025 Jun 2;66(6):6
Investigative ophthalmology & visual science 2025 Jun 2;66(6):6
A Novel Modulator of Resistance for Oxaliplatin-Based Therapy for Colorectal Cancer: The ESCRT Family Member VPS4A.
Abdelrazik NM, Patel A, Conn A, Sutton CW, Kantamneni S, Shnyder SD
Cells 2025 Jun 19;14(12)
Cells 2025 Jun 19;14(12)
Combination of Ginsenoside Compound K and Anti-PD1 Inhibits Pancreatic Cancer by Activating CXCL13-CXCR5 Signaling Axis.
Shang S, Yang H, Fan D, Deng J
Journal of agricultural and food chemistry 2025 Jun 18;73(24):15125-15137
Journal of agricultural and food chemistry 2025 Jun 18;73(24):15125-15137
Antrodia cinnamomea Extract Attenuates Obesity by Targeting Adipogenic Pathways and Gut Dysbiosis in High-Fat Diet-Fed Mice.
Lin KT, Lee SY, Ya-Jy L, Wu PJ, Chang TC, Chang WL, Yen IC
International journal of molecular sciences 2025 Jun 18;26(12)
International journal of molecular sciences 2025 Jun 18;26(12)
Spatiotemporal Circadian Oscillator Manipulation for Enhanced Ovarian Cancer Therapy Using a Versatile Nanoplatform.
Lin J, Zhang Q, Xin Y, Lin K, Zhou Z, Yang X, Zhou Y, Wang Y, Li J, Yang H, Xie Z, Lu W, Bi Z, Guo Y, Zheng J, Shen J, Yang X, Shen J, Qi R
ACS applied materials & interfaces 2025 Jun 18;17(24):35023-35039
ACS applied materials & interfaces 2025 Jun 18;17(24):35023-35039
Paracrine Action of Bone Morphogenetic Protein 3 in Pulmonary Arterial Hypertension.
Halouani A, Mensiah E, Athumani Z, Katz MG, Jankowski K, Mansoori M, Rosen V, Ishikawa K, Hadri L, Sassi Y
bioRxiv : the preprint server for biology 2025 Jun 18;
bioRxiv : the preprint server for biology 2025 Jun 18;
The use of sialic acids as attachment factors is a common feature of Enterovirus-D species.
Filhol T, Mac Kain A, Joffret M-L, Jouvenet N, Caval V, Bessaud M
Journal of virology 2025 Jun 17;99(6):e0042925
Journal of virology 2025 Jun 17;99(6):e0042925
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes.
Yu Z, Xu W, Teng Y, Li T, Guo R, Li J, Li X, Li Y, Hao Y
European journal of histochemistry : EJH 2025 Jun 17;69(3)
European journal of histochemistry : EJH 2025 Jun 17;69(3)
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Xia T, Yin H, Zhu Q, Zhang K, Xie H, Shan Y, Zhang S, Zhu R, Li K, Miao M, Lu Y, Wang Z, Zhao J, You Y, You B
Cell reports. Medicine 2025 Jun 17;6(6):102146
Cell reports. Medicine 2025 Jun 17;6(6):102146
Mechanical tension-induced Dalrd3 elevation enhances osteogenic differentiation of bone suture stem cells by upregulating Id3 translation.
Chen J, Zhao Y, Zeng C, Tian G, Feng Z, Cao Y
Stem cell research & therapy 2025 Jun 17;16(1):309
Stem cell research & therapy 2025 Jun 17;16(1):309
Galectin-1: An important regulator in myeloid differentiation and acute myeloid leukemia as well as a promising prognostic indicator and therapeutic target.
Liu L, Cheng P, Cui J, Ren S, Yao M, Li L, Zhou H, Zhang X, Qin X, Liu Y, Zhang H, Wang L, Chen M
International immunopharmacology 2025 Jun 17;158:114835
International immunopharmacology 2025 Jun 17;158:114835
Human neural stem cell-derived small extracellular vesicles enhance functional recovery after ischemic stroke through the miR-362-3p/MCAM/Wnt/β-catenin axis.
Zhu Z, Zhang G, Ahmed W, Feng J, Wang C, Zhang Y, Wu G, Hong C, Zhang Q, Feng T, Liu J, Zhao A, Chen L
International immunopharmacology 2025 Jun 17;158:114826
International immunopharmacology 2025 Jun 17;158:114826
Halicin Reduces the Warburg Effect and Overcomes Drug Resistance by Activating the Pyruvate Kinase M2 Pathway for Triple-Negative Breast Cancer Treatment.
Gu H, You W, Zhou XH, Wang Z, Huo SH, Nie X, Feng YB, You YZ, Zhan X, Xia L
ACS omega 2025 Jun 17;10(23):24541-24554
ACS omega 2025 Jun 17;10(23):24541-24554
Calycosin treats acute myocardial infarction via NLRP3 inflammasome: Bioinformatics, network pharmacology and experimental validation.
Yuan HJ, Han QC, Yu H, Yu YD, Liu XJ, Xue YT, Li Y
European journal of pharmacology 2025 Jun 15;997:177621
European journal of pharmacology 2025 Jun 15;997:177621
NADPH oxidase 2 inhibitor GSK2795039 prevents against cardiac remodeling after MI through reducing oxidative stress and mitochondrial dysfunction.
Liu Y, Wu Z, Jin X, Ji M, Huang T, Meng P, Xu T, Wang Y, Lin Q, Zhao Y, You W, Ye F, Wu X
European journal of pharmacology 2025 Jun 15;997:177483
European journal of pharmacology 2025 Jun 15;997:177483
Acetaldehyde dehydrogenase 2 attenuates lipopolysaccharide -induced endothelial barrier damage by inhibiting mitochondrial fission in sepsis-associated encephalopathy.
Wang S, Liu Z, Li R, Wang L, Wu Y, Zhang W, Yu Y
European journal of pharmacology 2025 Jun 15;997:177468
European journal of pharmacology 2025 Jun 15;997:177468
Carbon monoxide gas molecules: Therapeutic mechanisms in radiation-induced lung injury.
Li Y, Zhou B, Liu D, Nie G, Yang F, Chen J, Cheng S, Kang Y, Liu B, Dong B, Liu M
Journal of colloid and interface science 2025 Jun 15;688:250-263
Journal of colloid and interface science 2025 Jun 15;688:250-263
Protein Kinase D Knockdown Alleviates Vascular Calcification Through P53-SLC7A11 Axis-Mediated Ferroptosis.
He W, Meng Y, Liu W, Geng J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70706
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70706
Aspirin Suppresses Aromatase-Mediated Estrogen Biosynthesis to Alleviate Polycystic Ovary Syndrome by the Inhibition of Adenylate Cyclase.
Shi XK, Sheng YW, Cao DY, Shi N, Zhang GL, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70688
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70688
METTL3 Modulates Radiation-Induced Cardiac Fibrosis via the Akt/mTOR Pathway.
Qiao S, Tang C, Zhu J, Feng Y, Xiang L, Zhu J, Gu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70666
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70666
HBV-induced N6 methyladenosine modification of PARP1 enhanced AFB1-related DNA damage and synergistically contribute to HCC.
Zhou X, Li T, Xie H, Huang H, Yang K, Zeng X, Peng T
Ecotoxicology and environmental safety 2025 Jun 15;298:118254
Ecotoxicology and environmental safety 2025 Jun 15;298:118254
Neurotransmitter imbalance and amygdala synaptic plasticity in lumbar disc herniation-induced chronic pain and related emotional Disturbances:A multi-omics analysis.
Huang Z, Tan H, Fu Y, Xie H, Tan H, Gao K, Lou H
Neuropharmacology 2025 Jun 15;271:110405
Neuropharmacology 2025 Jun 15;271:110405
Red nucleus mGluR4 and mGluR8 inhibit nociception and the development of neuropathic pain by restraining the expressions of TNF-α and IL-1β.
Xu YL, Xia YT, Zhang MM, Li YJ, Tao XX, Li K, Yang QQ, Tian X, Wu JB, Shi YT, Wang JY, Zeng XY
Neuropharmacology 2025 Jun 15;271:110387
Neuropharmacology 2025 Jun 15;271:110387
Transcranial magnetic stimulation through attenuating blood-spinal cord barrier disruption and reducing inflammatory response to improve motor function in rats with spinal cord injury.
Xu Q, Zhang Z, Zhai Y, Chen J, Xu J, Chen H, Lu J
Brain research bulletin 2025 Jun 15;226:111385
Brain research bulletin 2025 Jun 15;226:111385
Genome-guided discovery of coublibactins from Nocardia coubleae and their gallium complexes with potent antileukemic activity.
Tao Q, Cai T, Xiao Y, Han T, Shen L, Cheng C, Xu S, Li A, Zhang P, Chen J, Zhang Y, Tong Q, Cai X
Bioorganic chemistry 2025 Jun 15;160:108508
Bioorganic chemistry 2025 Jun 15;160:108508
A Single-Chain Variable Fragment Antibody Alleviates Inflammation and Apoptosis of Neurons by Inhibiting Tau Aggregation.
Wang Z, Lin J, Chang P, Sun M, Li S
Biomolecules 2025 Jun 15;15(6)
Biomolecules 2025 Jun 15;15(6)
Generation and characterization of a DYNLT1-knockout mouse model reveals electrophysiological alterations and potential mechanistic contributors to atrial fibrillation.
Chen T, Wang Z, You X, Guo W, Chua Y, Jiang Q, Gao Y
Biology open 2025 Jun 15;14(6)
Biology open 2025 Jun 15;14(6)
Tumor-derived CXCL5 promotes 5-fluorouracil resistance in colorectal cancer cells via p21 downregulation.
Xu W, Wang J, Han W, Sun J, Yang X, Li X, Pei D
Medical oncology (Northwood, London, England) 2025 Jun 13;42(7):257
Medical oncology (Northwood, London, England) 2025 Jun 13;42(7):257
KLF4 mediates the contradictory effects of phenylethyl isothiocyanate in gastric cancer intervention.
Zhang Q, Yang C, Zhou B, Gao X, Zhong C, Shi Y, Cao H, Zhu M
Medical oncology (Northwood, London, England) 2025 Jun 12;42(7):253
Medical oncology (Northwood, London, England) 2025 Jun 12;42(7):253
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Yu S, Liu K, Zhou F, Yang X, Zhang J, Yu K, Zhu Y, Qin L, Peng T, Zhang C, He Y
Journal of ethnopharmacology 2025 Jun 12;349:119965
Journal of ethnopharmacology 2025 Jun 12;349:119965
Deciphering the polypharmacology of Dingzhi Xiaowan against comorbid depression: Integrated metabolomics of brain tissue and network pharmacology analysis in chronic restraint stress (CRS)-LPS model.
Chu H, Sun N, Tang Q, Yu X, Li L, Chang H
Journal of ethnopharmacology 2025 Jun 12;349:119960
Journal of ethnopharmacology 2025 Jun 12;349:119960
Qingfei Litan decoction alleviated Klebsiella pneumoniae-induced pneumonia by targeting the TLR4/MyD88/NF-κB axis via miR-146a-5p.
Wei R, Zeng Z, Chen S, Shi Y, Ding Q
Journal of ethnopharmacology 2025 Jun 12;349:119947
Journal of ethnopharmacology 2025 Jun 12;349:119947
Integrator loss leads to dsRNA formation that triggers the integrated stress response.
Baluapuri A, Zhao NC, Marina RJ, Huang KL, Kuzkina A, Amodeo ME, Stein CB, Ahn LY, Farr JS, Schaffer AE, Khurana V, Wagner EJ, Adelman K
Cell 2025 Jun 12;188(12):3184-3201.e21
Cell 2025 Jun 12;188(12):3184-3201.e21
Melatonin mitigates ovarian aging through regulation of the YTHDF2/m (6)A/UBE3C axis.
Xia W, Wang X, Li J, Zhang M, Lu J, Li H, He Q, Meng Q, Huang B
Acta biochimica et biophysica Sinica 2025 Jun 11;57(9):1529-1538
Acta biochimica et biophysica Sinica 2025 Jun 11;57(9):1529-1538
Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway.
Yu C, Lin W, Yang J, Jiang Q, Liu W, Liu H, Lin Y, Wang L, Chen L, Huang Y, Chen L
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):233
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):233
Overexpression of miR-671-3p alleviates postmenopausal osteoporosis by targeting GREM2 to activate BMP2/SMAD signaling pathway.
Liang Y, Gu C, Wang P, Gu C, Ma H, Ren S
Hereditas 2025 Jun 11;162(1):102
Hereditas 2025 Jun 11;162(1):102
tRF-22-WE8SPOX52 promotes progression of breast cancer by down-regulating MAP2K4.
Fu Y, Hu H, Wang D, Qian T, Huang X, Zhong S
Medical oncology (Northwood, London, England) 2025 Jun 10;42(7):248
Medical oncology (Northwood, London, England) 2025 Jun 10;42(7):248
Vinpocetine-mediated multidimensional active targeted delivery across the blood-brain barrier.
Ma Z, Liu X, Xie X, Fang Y, Jiang D, Zhao C, Li P, Fu Y, Ye L, Gao Y, Wu S, Li C
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113768
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113768
Bioengineered bacterial extracellular vesicles for targeted delivery of an osteoclastogenesis-inhibitory peptide to alleviate osteoporosis.
Kong X, Liu H, Chen S, Liu Z, Chen Q, Li X, Hu H, Su J, Shi Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113751
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113751
Novel mutation SLFN14 T853fs associated with inherited macrothrombocytopenia.
Xie H, Tang S, Shao J, Yang M, Tong H, Zhang L, Zhong M, Yu X, Bi L, Wang Y, Ou R, Ling C, Zhu L
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102554
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102554
Hyperandrogen-induced imbalance of FOXO4-AR regulatory loop contributes to ovulatory disorders in polycystic ovary syndrome.
Zhou R, Wang Z, Dong M, Wang S, Li X, Huang J, Zhang X, Liu F
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102543
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102543
Lipidomics reveals biomarkers of the efficacy of first-line ICI therapy combined with chemotherapy in NSCLC.
Yu J, Xu H, Xiong F, Liu X, Lingfei M, Gao H, Li Y
Journal of translational medicine 2025 Jun 10;23(1):638
Journal of translational medicine 2025 Jun 10;23(1):638
Combined protein and transcriptomics identifies DCTPP1 as a putative biomarkers for predicting immunotherapy responsiveness in gastric cancer patients.
Wei J, Qin Y, Zhang L, Gong X
Anti-cancer drugs 2025 Jun 1;36(5):415-426
Anti-cancer drugs 2025 Jun 1;36(5):415-426
The PPARβ/CERK/C1P signaling pathway is a potential mechanism by which antimony exposure promotes prostate cancer cell proliferation.
Shi J, Li Z, Sun X, Zhao D, Kang S, Cao F, Zhang Z, Zhang C
Ecotoxicology and environmental safety 2025 Jun 1;297:118268
Ecotoxicology and environmental safety 2025 Jun 1;297:118268
Ambient fine particulate matter induces cardiac fibrosis through triggering ferroptosis by heme degradation induced-iron overload.
Jiang J, Li Y, Chen Y, Wu Q, Ding S
Ecotoxicology and environmental safety 2025 Jun 1;297:118227
Ecotoxicology and environmental safety 2025 Jun 1;297:118227
Spinal astrocyte-derived M-CSF mediates microglial reaction and drives visceral hypersensitivity following DSS-induced colitis.
Wu K, Shao S, Dong YT, Liu YY, Chen XH, Cheng P, Qin X, Peng XH, Zhang YM
Neuropharmacology 2025 Jun 1;270:110373
Neuropharmacology 2025 Jun 1;270:110373
Pharmacological inhibition of Kv1.3 channel reduces sevoflurane-induced cognitive impairment through NLRP3-dependent microglial modulation.
Li B, Gao Y, Han H, Wang Z, Zhang Y, Yu L, Ling Y
Brain research bulletin 2025 Jun 1;225:111351
Brain research bulletin 2025 Jun 1;225:111351
A novel MMP-9 inhibitor exhibits selective inhibition in non-small-cell lung cancer harboring EGFR T790M mutation by blocking EGFR/STAT3 signaling pathway.
Li L, Lu M, Wang H, Ma X, Du W, Zhao Y, Zeng S, Peng Y, Zhang G
Bioorganic chemistry 2025 Jun 1;159:108393
Bioorganic chemistry 2025 Jun 1;159:108393
Muscle-homing peptides modified biomimetic curcumin nanoparticles ameliorate skeletal muscle dysfunction in aging mice.
Xie J, Huang Z, Gao N, Feng H, Wang B, Gao S, Tian H, Wu C, Liu C
Redox biology 2025 Jul;84:103679
Redox biology 2025 Jul;84:103679
PINK1 Loss of Function Selectively Alters the Mitochondrial-Derived Vesicle Pathway.
Collier CL, Ruedi C, Thorne NJ, Tumbarello DA
FASEB bioAdvances 2025 Jul;7(7):e70030
FASEB bioAdvances 2025 Jul;7(7):e70030
Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition.
Ding Y, Zhang L, Zhao W, Wang T, Shi Y, Zhuang C, Qu Z
Molecular nutrition & food research 2025 Jul;69(13):e70103
Molecular nutrition & food research 2025 Jul;69(13):e70103
GDF11 Regulates M1 and M2 Polarization of BV2 Microglial Cells via p38 MAPK Signaling Pathway.
Zhao X, Qin R, Li G, Lv G, Zhao D, Kong L, Qi M, Li P
Molecular neurobiology 2025 Jul;62(7):9290-9305
Molecular neurobiology 2025 Jul;62(7):9290-9305
Pilot Exploration of RGMa-BMP4 Signaling in Neutrophil Activation in NMOSD: Integrating Clinical and Molecular Insights.
Zhang W, Cui L, Zhang Y, He Y, Li X, Wang Y, Jiao J, Peng D, Jin M, Xiao C
Molecular neurobiology 2025 Jul;62(7):9151-9161
Molecular neurobiology 2025 Jul;62(7):9151-9161
Inhibiting the REV-ERBα expression protects against mechanical overloading-induced cartilage clock disruption and osteoarthritis progression.
Xu X, Wang D, Ni B, Xu H, Wu Z, He T, Zhang Y, Hao X, Ding G, Zhang X, Meng QJ, Yang L
Journal of orthopaedic translation 2025 Jul;53:112-125
Journal of orthopaedic translation 2025 Jul;53:112-125
ω-3 PUFAs Alleviate GJ-Cx43 Uncoupling Induced by Long-Term Isoflurane Exposure by Activating the Wnt/β-catenin Signaling Pathway in Astrocytes.
Wang Z, Dong R, Han Y, Peng L, Liu S, Ma Z, Xia T, Gu X
Cell biology international 2025 Jul;49(7):865-877
Cell biology international 2025 Jul;49(7):865-877
GDF15 attenuates Parkinson's disease progression via suppressing the activation of cGAS-STING pathway.
Wang J, Geng T, Yao X, Liu Y
Molecular and cellular biochemistry 2025 Jul;480(7):4449-4466
Molecular and cellular biochemistry 2025 Jul;480(7):4449-4466
PUS7 promotes the progression of pancreatic cancer by interacting ANLN to activate MYC pathway.
Jiang Y, Cheng Q, Zhang Y, Zhong J
Molecular and cellular biochemistry 2025 Jul;480(7):4401-4415
Molecular and cellular biochemistry 2025 Jul;480(7):4401-4415
The role of mitochondrial dysfunction in the protective effect of ginger derived extracellular vesicles on hepatic stellate cells against cytotoxicity.
Yang J, Yang Y, Zhang X, Qin Y, Sato T, Qing S, Wang Y, Ye X, Xu M, Liu Y, He Q, Zheng Y
Molecular and cellular biochemistry 2025 Jul;480(7):4297-4309
Molecular and cellular biochemistry 2025 Jul;480(7):4297-4309
FNDC5/Irisin exacerbates APAP-induced acute liver injury through activating JNK/NF-κB and inflammatory response.
Zhang QH, Jin LM, Lin MS, Wang MX, Cui YQ, Ye JX, Xiong YQ, Luo W, Zhu WW, Liang G
Acta pharmacologica Sinica 2025 Jul;46(7):1946-1957
Acta pharmacologica Sinica 2025 Jul;46(7):1946-1957
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy.
Huang H, Fang L, Zhu C, Lv J, Xu P, Chen Z, Zhang Z, Wang J, Wang W, Xu Z
Oncogene 2025 Jul;44(28):2357-2371
Oncogene 2025 Jul;44(28):2357-2371
TP53INP2 promotes mitophagic degradation of YAP to impede dedifferentiated liposarcoma development.
Wang Y, Huang Y, Wang L, Chen Z, Zhou L, Xiang F, Li G, Yang J, Chen R, Xu Q, Shen Y
Oncogene 2025 Jul;44(25):2054-2063
Oncogene 2025 Jul;44(25):2054-2063
Advanced N-glycoproteomics and proteomics approach revealed sexually dimorphic molecular signatures in primary mouse hepatocyte.
Yang Q, Zhang Y, Zhang H, Yang Z, Feng Y, Ye B, Gong P, Qian G, Li D
Analytical and bioanalytical chemistry 2025 Jul;417(17):3893-3908
Analytical and bioanalytical chemistry 2025 Jul;417(17):3893-3908
Tinosinenside A inhibits neuroinflammation and protects HT22 cells by suppressing the TLR4/NF-κB/NLRP3 signaling pathway in BV2 cells.
Xie Y, Qin Y, Wang J, Xu Z, Chen L, Kuang Y, Yang R, Huang L
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8947-8962
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8947-8962
SPATA2/CYLD Pathway-Dependent Deubiquitylation of p53 Promotes Ferroptosis in Rat Heart After Ischaemia/Reperfusion Through Suppression of SLC7A11.
Duan DQ, Li MR, Lu LQ, Yao BF, Huang LL, Luo XJ, Peng J
Heart, lung & circulation 2025 Jul;34(7):719-729
Heart, lung & circulation 2025 Jul;34(7):719-729
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Ma MQ, Yang C, Jin SY, Yang Y, Pan YY, Lin XH
Molecular medicine reports 2025 Jul;32(1)
Molecular medicine reports 2025 Jul;32(1)
Cataract-causing variant G119R impaired the oligomeric homeostasis of βB2-crystallin with lower structural stability and more sensitivity to the environmental stress.
Guo J, Tian Q, Wu C, Zhang Y, Chen S, Liao Y, Liu J, Yao K, Chen X, Hu L, Yu Y
International journal of biological macromolecules 2025 Jul;318(Pt 3):145185
International journal of biological macromolecules 2025 Jul;318(Pt 3):145185
HIV-1 Tat mediates microglial NLRP3 inflammasome activation and neurotoxicity by inducing cytosolic mtDNA stress.
Yang X, Han P, Li M, Xue Y, Yu X, Jiang M, Wang H, Zhang J, Liu H, Bao D
International journal of biological macromolecules 2025 Jul;318(Pt 3):145093
International journal of biological macromolecules 2025 Jul;318(Pt 3):145093
Nano-pectic polysaccharide from vinegar-baked Radix Bupleuri enhances methotrexate efficacy against hepatocellular carcinoma via BCRP and MRP2 downregulation.
Wang X, Gan J, Han M, Wu Y, Liu L, Zhao Y, Zhao R
International journal of biological macromolecules 2025 Jul;318(Pt 2):145046
International journal of biological macromolecules 2025 Jul;318(Pt 2):145046
miR166u -enriched Polygonatum sibiricum exosome-like nanoparticles alleviate colitis by improving intestinal barrier through the TLR4/AKT pathway.
Wei C, Chen Y, Chen J, Cao F, Cheng J, Pan C, Wei Y, Liu T, Jin Y, Yang G
International journal of biological macromolecules 2025 Jul;318(Pt 1):144802
International journal of biological macromolecules 2025 Jul;318(Pt 1):144802
A high-performance chitosan-grafted Cu(Ⅱ) coating improves endothelialization and mitigates the degradation of biodegradable magnesium alloy stents.
Li P, Qi X, Liu D, Ma J, Wang S, Yang K, Yan W, Chen S
Biomaterials 2025 Jul;318:123161
Biomaterials 2025 Jul;318:123161
FoxO4 reduces the damage and mechanism of PEDV-infected IPEC-J2 cells through the NF-κB/MLCK pathway.
Wei Y, Zhao S, Zhao H, Bao D, Liu J, Shao H, Zhang S, Yi S, Wang K, Hu G
Veterinary microbiology 2025 Jul;306:110568
Veterinary microbiology 2025 Jul;306:110568
Quantification profiles of enzyme activity, secretion, and psychosine levels of Krabbe disease galactosylceramidase missense variants.
Peng H, Lam YW, Lau KF, Zhou Z, Herdt AR, Gelb MH, Lee CW
The Journal of biological chemistry 2025 Jul;301(7):110315
The Journal of biological chemistry 2025 Jul;301(7):110315
Transthyretin, a novel prognostic marker of POCD revealed by time-series RNA-sequencing analysis.
Liang X, Song C, Lin J, Li S, Li L, Dai G, Zhang R, Zou OM, Yao H, Zhou L, Zou Y
Molecular psychiatry 2025 Jul;30(7):3103-3119
Molecular psychiatry 2025 Jul;30(7):3103-3119
Oxaliplatin accelerates immunogenic cell death by activating the cGAS/STING/TBK1/IRF5 pathway in gastric cancer.
Zhao S, Sun D, Yu H, Wang M, Xu B, Wang Y, Hu F, Wang X, Zhang J, Wang Y, Chai J
The FEBS journal 2025 Jul;292(14):3814-3828
The FEBS journal 2025 Jul;292(14):3814-3828
Myeloid MyD88 Mediates Macrophage Infiltration and Activation in Ang II-Induced Cardiac Hypertrophy.
Lin K, Yang N, Hu C, Luo W, Huang P, Liang G, Wang Y
Journal of cellular and molecular medicine 2025 Jul;29(14):e70733
Journal of cellular and molecular medicine 2025 Jul;29(14):e70733
HBx Drives Liver Cancer Stem Cell Generation Through Stimulating Glucose Metabolic Reprogramming.
Liu J, Wu X, Yin Q, Zhang L, Liu K, Huang K, Xu J, Li X, Lin B, Zhu M, Li M
Journal of cellular and molecular medicine 2025 Jul;29(14):e70722
Journal of cellular and molecular medicine 2025 Jul;29(14):e70722
Exploration of the Potential Bioactive Compounds and Functional Mechanism of Chaihu Sanshen Capsule in Ameliorating Myocardial Ischaemia-Reperfusion Injury: A Serum Pharmaco-Chemistry With Network Pharmacology Analysis.
Wang W, Zhang Z, Liu R, Zheng Y, Hu Y, Li X, Shen Z, Yuan H, Liu J
Journal of cellular and molecular medicine 2025 Jul;29(14):e70666
Journal of cellular and molecular medicine 2025 Jul;29(14):e70666
Identification of LDHA as a Potential Therapeutic Target for Pulmonary Hypertension Through Modulation of Endothelial-To-Mesenchymal Transition.
Yao M, Zhong K, Zheng X, Yang Z, Li C, Gu Y, Chen Z
Journal of cellular and molecular medicine 2025 Jul;29(13):e70692
Journal of cellular and molecular medicine 2025 Jul;29(13):e70692
A Dendrobium chrysotoxum extract erianin induce AML cells death by activating PPARɑ and downregulating PI3K/AKT signaling pathways.
Deng Y, Zhong L, Zhao Y, Wan P, Zhang Y, Liao Y, Zhang H, Wang M, Liu B
Toxicon : official journal of the International Society on Toxinology 2025 Jul;261:108371
Toxicon : official journal of the International Society on Toxinology 2025 Jul;261:108371
Scutellarein ameliorates pulmonary arterial hypertension via sirtuin 1 mediated deacetylation of nicotinamide nucleotide transhydrogenase.
Tang H, Ning K, Wu B, Wang X, He J, Li P, Pan L, Zhang J, He Y, Bian S, Ma X, Zhang J, Liu C, Qin Z, Hu H
Biochemical pharmacology 2025 Jul;237:116932
Biochemical pharmacology 2025 Jul;237:116932
Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis.
Chen J, Li M, Mao J, Wang X, Guo B, Chen X, Kalvakolanu DV, Hong J, Yang M, Liu J, Luo Q, Yang J, Sun X, Tian Y, Zhang L
Biochemical pharmacology 2025 Jul;237:116926
Biochemical pharmacology 2025 Jul;237:116926
Discovery of a novel BCL-2 inhibitor GW806742X for the treatment of TNBC.
Liu W, Xu J, Chen L, Zhang D, Zhang J, Lu L, Zhang X, Huang X, Zhang G
Biochemical pharmacology 2025 Jul;237:116925
Biochemical pharmacology 2025 Jul;237:116925
Pasteurized Akkermansia muciniphila ameliorates preeclampsia via inhibiting mitochondrial dysfunction-mediated placental apoptosis in vivo and in vitro.
Wang H, Wang Y, Zhong Y, Yu B, Liu D, Jia C, Wu J, Zeng G, Wang Q, Liu F, Sheng C, Huang L
Free radical biology & medicine 2025 Jul;234:233-247
Free radical biology & medicine 2025 Jul;234:233-247
Identification of cytochrome P450 2E1 as a novel target in neuroinflammation and development of its inhibitor Q11 as a treatment strategy.
Yang R, Deng MY, Yang LK, Wang GZ, Ma J, Wen Q, Gao N, Qiao HL
Free radical biology & medicine 2025 Jul;234:220-232
Free radical biology & medicine 2025 Jul;234:220-232
High soluble expression and characterization of human GalNAc transferase T2 and T11 in Escherichia coli.
Wang Y, Zhang H, Shi W, Rong Y, Mao W, Wang L, Tang W, Kong Y, Wang S
Protein expression and purification 2025 Jul;231:106712
Protein expression and purification 2025 Jul;231:106712
Cardiac Troponin I Promotes the Development of NSCLC Cells Through the Expression of Notch and Kras Proteins.
Wang L, Cao J, Chen H, Xue N, Yu H, Zhao S, Wang X, Li L
Iranian journal of biotechnology 2025 Jul;23(3):e3976
Iranian journal of biotechnology 2025 Jul;23(3):e3976
Activation of spinal PGC-1α regulates microglial polarization through a feedback loop between ROS-mediated mitochondrial dysfunction and the NLRP3 inflammasome in neuropathic pain.
Chen Y, Ling G, Xu Q, Zhu Q, Huang T, Su T, Xie Y, Zhong Y
Brain research bulletin 2025 Jul;227:111365
Brain research bulletin 2025 Jul;227:111365
Optineurin knock-out forms TDP-43 aggregates to regulate TDP-43 protein levels despite autophagic up-regulation and aberrant TDP-43 expression.
Maetani Y, Kurashige T, Tada Y, Kume K, Watanabe T, Sotomaru Y, Yamanaka K, Maruyama H, Kawakami H
Neuroscience research 2025 Jul;216:104893
Neuroscience research 2025 Jul;216:104893
Unripe apple polyphenols extract improves intestinal inflammation and restructures gut microbiota in spontaneously hypertensive rats.
Li J, Wu Q, Ling X, Ma X, Gan X, Wei W, Du J, Zhou L, Jia X, Kan J, Zhao M
Food research international (Ottawa, Ont.) 2025 Jul;212:116418
Food research international (Ottawa, Ont.) 2025 Jul;212:116418
Sex-biased zinc responses modulate ribosomal protein expression, protein synthesis and social defects in Cttnbp2 mutant mice.
Fang YL, Yen TL, Liu HC, Wang TF, Hsueh YP
Neurobiology of disease 2025 Jul;211:106932
Neurobiology of disease 2025 Jul;211:106932
Glyphosate exposure impairs glucose and lipid metabolism by disturbing the circadian clock system in mice liver.
Xiao B, Jiang H, Dong H, Li C, Zhang H, Gao D, Wang A, Jin Y, Chen H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Jul;201:115436
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Jul;201:115436
A-485 alleviates fibrosis and apoptosis in kidney by disrupting tandem activation of acetylation and phosphorylation on STAT3.
Du C, Zhu Y, Duan J, Yang Y, Ren Y, Mu L, Yan Z, Li G, Wang H, Shi Y, Yao F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118217
SLAMF9 aggravates myocardial ischemia reperfusion injury through activating the hippo-yap pathway.
Liu T, Guo X, Fu Y, Zhang W
Biochimica et biophysica acta. General subjects 2025 Jul;1869(8):130821
Biochimica et biophysica acta. General subjects 2025 Jul;1869(8):130821
Integrating LC-MS and molecular docking technology to investigate the effect of Spatholobi caulis flavonoids in alleviating primary dysmenorrhea via regulating the RhoA/ROCK pathway.
Zhang X, Weng J, Luo Y, Liu H, Yan J, Gong Z, Kong C, Li X, Yang L, Jiang M
Fitoterapia 2025 Jul;184:106631
Fitoterapia 2025 Jul;184:106631
NRF2 modulates WNT signaling pathway to enhance photodynamic therapy resistance in oral leukoplakia.
Xu T, Zhong L, Liu Q, Wang F, Kuang W, Liang J, Yang D, Zhou X, Dan H, Zhao H, Li T, Zeng X, Li J, Chen Q
EMBO molecular medicine 2025 Jul;17(7):1794-1824
EMBO molecular medicine 2025 Jul;17(7):1794-1824
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Li XJ, Huang KX, Wang KX, Liu R, Wang DC, Liang YR, Hao EJ, Wang Y, Guo HM
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Disorder of phospholipid metabolism in the renal cortex and medulla contributes to acute tubular necrosis in mice after cantharidin exposure using integrative lipidomics and spatial metabolomics.
He T, Lin K, Xiong L, Zhang W, Zhang H, Duan C, Li X, Zhang J
Journal of pharmaceutical analysis 2025 Jul;15(7):101210
Journal of pharmaceutical analysis 2025 Jul;15(7):101210
Oligomeric proanthocyanidin attenuates asthma severity and airway remodeling by modulating epithelial-smooth muscle cell interactions.
Gu S, Gu Y, Gu H, Zhong X, Liang W, Liu Y, Yao X, Ma Y, Zeng X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156798
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156798
Ji-Ming-San enhances intestinal circadian rhythms and mitigates colitis in mice: The role of epithelial RORα.
Pan Z, Liu J, Lin S, Li Z, Qin S, Wu H, Li F, Wu B, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156759
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156759
Peiyuan Ningshen-ointment alleviates learning and memory impairment induced by sleep deprivation through activating the cAMP/PKA signaling pathway.
Wei XY, Xu FP, Chen XB, Xu Q, Deng LY, Sun C, Chen XY, Tan F, Yang ZM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156469
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156469
Medium-chain triglyceride attenuates obesity by activating brown adipose tissue via upregulating the AMPK signaling pathway.
Jia M, Yue H, Wang X, Zong A, Xu T, Xu YJ, Liu Y
The Journal of nutritional biochemistry 2025 Jul;141:109914
The Journal of nutritional biochemistry 2025 Jul;141:109914
HMGB1 Accelerates Wound Healing by Promoting the Differentiation of Epidermal Stem Cells via the "HMGB1-TLR4-Wnt/Notch" Axis.
Zhen M, Zhu Y, Wang P, Liu X, Zhu J, Liu H, Li J, Zhao J, Shu B
Advances in wound care 2025 Jul;14(7):365-380
Advances in wound care 2025 Jul;14(7):365-380
Downregulation of miR-27a-3p induces endothelial injury and senescence and its significance in the development of coronary heart disease.
Song CY, Huang HZ, Yan TT, Cui CX, Wu HY, Chen J, Peng JH, Chen NY, Tang J, Pan SL
Cellular signalling 2025 Jul;131:111759
Cellular signalling 2025 Jul;131:111759
Polygonati Rhizoma Polysaccharides Ameliorated Diabetic Kidney Disease in db/db Mice via Inhibiting TGFβ/Smad2 Signaling Pathway.
Mei X, Ren Z, Gao Z, Chen S, Chen X, Zhou Q, Tong Y, Dai G
Food science & nutrition 2025 Jul;13(7):e70677
Food science & nutrition 2025 Jul;13(7):e70677
Leucine-Rich Repeat Containing 15 Promotes the Inflammatory Response in Rheumatoid Arthritis by Regulating NF-κB Pathway.
Xin M, Xia G, Guan X, Xi G, Fu M
Immunity, inflammation and disease 2025 Jul;13(7):e70220
Immunity, inflammation and disease 2025 Jul;13(7):e70220
Depalmitoylase ABHD16A negatively regulates the anti-hepatitis B virus activity of IFITM1.
Wen X, Liu M, Fan Y, Xu J, Wang Z, Mao L, Gu W, Shi X, Xu J
Microbiology spectrum 2025 Jul;13(7):e0309524
Microbiology spectrum 2025 Jul;13(7):e0309524
C1q(+) Macrophage-Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma.
Liu Y, Huang C, Luo M, Lu W, Zhang B, Bai L, Zheng S, Tan Y, Li S, Wang H, Gong L, Guan X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2503434
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2503434
Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non-small Cell Lung Cancer.
Jin M, Huang Y, Li B, Wang Y, Li Y, Chen Z, Tang Z, Liu C, Zhang L, Yuan X, Tian J, Liu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2502008
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2502008
Bovine collagen peptides and peptide-calcium complexes inhibit RANKL-induced osteoclast differentiation in RAW 264.7 macrophages.
Liu Y, Zhu Y, Zhao Y, Wang J, Yu Y, Zhu J, Jin G
Journal of the science of food and agriculture 2025 Jul;105(9):4999-5008
Journal of the science of food and agriculture 2025 Jul;105(9):4999-5008
Polysaccharides of Atractylodes macrocephala Koidz alleviate bursa of Fabricius involution in Magang geese by inhibiting the Wnt signaling pathway.
Liang W, Liu Z, Xie P, Cen L, Zhou X, Hong L, Gong S, Li W, Cao N, Tian Y, Xu D, Li B
Poultry science 2025 Jul;104(7):105227
Poultry science 2025 Jul;104(7):105227
Protective effects of polysaccharide of Atractylodes macrocephala Koidz and Jiawei Si-jun-zi Decoction on gut health and immune function in cyclophosphamide-treated chicks.
Lu B, Pan S, He J, Li B, Cao N, Fu X, Liu W, Huang Y, Tian Y, Xu D, Li W
Poultry science 2025 Jul;104(7):105160
Poultry science 2025 Jul;104(7):105160
UBC9 overexpression promotes proliferation and metastasis in gastric cancer via ATF2.
Wang Q, Li S, Xu Y, Chen Y, Xu C, He Q, Ye Y, Huang Y, Wu Y, Guo K, Wei Y, Huang Y, Liu Y, Lin Q, Wang S, Li F, Huang M, Xue F, Lin Y
World journal of surgical oncology 2025 Jul 9;23(1):270
World journal of surgical oncology 2025 Jul 9;23(1):270
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Jiang R, Wang H, Zhong F, Hu Y, Liu J, Chen Y, Su W, Cao S, Deng Q, Zhou Q
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Design, synthesis and anti-cancer activity of novel 1,2,3-triazole hybrids of erlotinib against cervical cancer via MAPK signaling pathway.
Wang L, Hou X, Huang M, He B, Mao L, Hu Z, Li L, Guo J, Peng L
Scientific reports 2025 Jul 9;15(1):24582
Scientific reports 2025 Jul 9;15(1):24582
Akt isoform specificity drives intrinsic immune regulation during HSV-1 infection.
Suryawanshi RK, Patil CD, Borase H, Shukla D
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 8;122(27):e2504962122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 8;122(27):e2504962122
Leucine-rich repeat-containing protein 19 suppresses colorectal cancer by targeting cyclin-dependent kinase 6/E2F1 and remodeling the immune microenvironment.
Huang SS, Chen W, Vaishnani DK, Huang LJ, Li JZ, Huang SR, Li YZ, Xie QP
World journal of gastroenterology 2025 Jul 7;31(25):107893
World journal of gastroenterology 2025 Jul 7;31(25):107893
Mechanism of Myh3 gene regulation of intramuscular fat content in Beijing black pigs via the MAPK signaling pathway.
Luo Y, Xu G, Zhang C, Wen Z, Chu H, Dai Y, Hong L, Zhang J, Vignon AS, Sun C, Zhang L, Pu L
BMC genomics 2025 Jul 7;26(1):642
BMC genomics 2025 Jul 7;26(1):642
Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling.
Wang Y, Zhang A, Chen Y, Qi D, Peng C, Liang Z, Guo J, Gu Y, Li H
Scientific reports 2025 Jul 7;15(1):24311
Scientific reports 2025 Jul 7;15(1):24311
Cardiac-specific overexpression of PRMT5 exacerbates pressure overload-induced hypertrophy and heart failure.
Katanasaka Y, Sunagawa Y, Sakurai R, Tojima M, Naruta R, Hojo Y, Kawase Y, Hamabe-Horiike T, Mori K, Hasegawa K, Morimoto T
Journal of biomedical science 2025 Jul 6;32(1):61
Journal of biomedical science 2025 Jul 6;32(1):61
Design, synthesis, and biological evaluation of quinolinyl-ureido-phenyl-hydrazide derivatives and quinolinyl-hydrazide derivatives as anticancer agents targeting Nur77-mediated ferroptosis.
Gao YF, Yang YJ, Qin JB, Yu MY, Hu SW, Zhang HF, Lin FH, Hu HY, Fang MJ, Zeng JZ
European journal of medicinal chemistry 2025 Jul 5;291:117559
European journal of medicinal chemistry 2025 Jul 5;291:117559
Multi-omics analysis identifies SNP-associated immune-related signatures by integrating Mendelian randomization and machine learning in hepatocellular carcinoma.
Kou Q, Wu Z, Zhao W, Liu Z, Qiao S, Mu Q, Zhang X
Scientific reports 2025 Jul 4;15(1):23930
Scientific reports 2025 Jul 4;15(1):23930
Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway.
Lokhande G, Singh KA, Roy S, Soukar J, Kersey A, Borkar P, Biswas S, Syed RUR, Keller A, Bayless KJ, Singh I, Gaharwar AK
Science advances 2025 Jul 4;11(27):eado1223
Science advances 2025 Jul 4;11(27):eado1223
Nuclear receptor FXR inhibits ferroptosis to alleviate hepatic ischemia-reperfusion injury by targeting GPX4 in a mouse model.
Chen M, Guo S, Huang X, Mo Q, Chen Q, Zhang S, Zhang Y, Liu C
Journal of molecular histology 2025 Jul 31;56(4):243
Journal of molecular histology 2025 Jul 31;56(4):243
Aggregation of the Constitutively Active K296E Rhodopsin Mutant Contributes to Retinal Degeneration.
Vasudevan S, Prakash V, Park PS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70848
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70848
LMOD2 interaction with ACTC1 regulates myogenic differentiation.
Wang K, Liu C, Yi L, Liufu S, Chen W, Liu X, Chen B, Xu X, Liu J, Liu X, Yin Y, Ma H
BMC genomics 2025 Jul 31;26(1):709
BMC genomics 2025 Jul 31;26(1):709
Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids.
Miao R, Liu C, Wang Y, Li H, Han C, Wang C, Tian Z, Liu J
Cell death discovery 2025 Jul 31;11(1):356
Cell death discovery 2025 Jul 31;11(1):356
Metabolic dysfunction promoted by mitochondrial DNA mutation burden drives retinal degeneration.
Johnathon S, Ke J, Stephanie A H, Maya M, Bonilha VL
bioRxiv : the preprint server for biology 2025 Jul 31;
bioRxiv : the preprint server for biology 2025 Jul 31;
A Novel Field Resistance Mechanism: Two Structural Variations in FgOs1 Confer Ultrahigh Fludioxonil Resistance in Fusarium graminearum without Disrupting FgOs1 Transcription or Translation.
Wang C, Cong W, Yang L, Hou Y
Journal of agricultural and food chemistry 2025 Jul 30;73(30):18669-18679
Journal of agricultural and food chemistry 2025 Jul 30;73(30):18669-18679
METTL3-mediated m (6)A modification facilitates Nectin-4-induced VNN1 upregulation and promotion of ESCC progression.
Long Y, Yang H, Zhang R, Zhao Q, Yang M, Song G, Liu K
Acta biochimica et biophysica Sinica 2025 Jul 30;58(2):353-368
Acta biochimica et biophysica Sinica 2025 Jul 30;58(2):353-368
RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis.
Feng J, Zheng B, Wang J, Xu Q, Ouyang Q, Li H, Jia T, Wang Y, Cai T, Feng Y, Zhang X, Li X, Ma X
Translational andrology and urology 2025 Jul 30;14(7):1849-1864
Translational andrology and urology 2025 Jul 30;14(7):1849-1864
Gypenosides Alleviate Hyperglycemia by Regulating Gut Microbiota Metabolites and Intestinal Permeability.
Wang R, Liu XF, Yang K, Yu LL, Liu SJ, Wang NN, Chen YM, Hu YQ, Qin B
Current issues in molecular biology 2025 Jul 3;47(7)
Current issues in molecular biology 2025 Jul 3;47(7)
Influence of Gut Microbiota-Derived Butyrate on Intestinal Uric Acid Excretion and Hyperuricemia Regulation by Cichorium intybus L.
Yang Y, Wang Y, Huang J, Xu Y, Yin X, Lin Z, Zhang B
International journal of molecular sciences 2025 Jul 3;26(13)
International journal of molecular sciences 2025 Jul 3;26(13)
Pantothenic acid ameliorates hepatic fibrosis by targeting IGFBP6 to regulate the TGF-β/SMADs pathway.
Jin Z, Jin Z, Liu Z, Yin Y, Zhang Y, Zhang Y, Kang J, Fang Y, Jiang W, Ning B
Communications biology 2025 Jul 29;8(1):1127
Communications biology 2025 Jul 29;8(1):1127
Cold Stress Regulates Muscle Development and Promotes Muscle Fiber Transformation by Regulating Mib1/Notch Pathway.
Zheng M, Qi J, Wang X, Fu T, Chang Z, Zhao T, Sun Y, Lu J, Yan Y, Wang H
Frontiers in bioscience (Landmark edition) 2025 Jul 28;30(7):40141
Frontiers in bioscience (Landmark edition) 2025 Jul 28;30(7):40141
Pilaralisib inhibits the replication of enteroviruses by targeting the PI3K/AKT signaling pathway.
Zhou J, Wang Y, Zhu G, Yan M, Li Z, Li L, Kuang J, Zhang W, Huang C, Ren F, Yang Q
Virology journal 2025 Jul 28;22(1):257
Virology journal 2025 Jul 28;22(1):257
Mefunidone treats pulmonary fibrosis by targeting SDH to regulate fibro-promoting macrophages.
Zhang X, He Y, Long L, Jiang G, Yao T, Cheng X, Peng Z, Hu G, Tao L, Meng J
International immunopharmacology 2025 Jul 28;160:114971
International immunopharmacology 2025 Jul 28;160:114971
Phytosterol-mediated disturbance of the lipid packing order in the plasma membrane regulates inflammatory response.
Wang X, Liu Y, Du F, Zong A, Xu T
Food & function 2025 Jul 28;16(15):6150-6159
Food & function 2025 Jul 28;16(15):6150-6159
ShenQiGan Extract Repairs Intestinal Barrier in Weaning-Stressed Piglets by Modulating Inflammatory Factors, Immunoglobulins, and Short-Chain Fatty Acids.
Guo R, Jiang C, Niu Y, Niu C, Chen B, Yuan Z, Hua Y, Wei Y
Animals : an open access journal from MDPI 2025 Jul 28;15(15)
Animals : an open access journal from MDPI 2025 Jul 28;15(15)
Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a.
Shen J, Gao L, Gao J, Wang L, Yan D, Wang Y, Meng J, Li H, Chen D, Wu J
Biomolecules 2025 Jul 27;15(8)
Biomolecules 2025 Jul 27;15(8)
A designer polyQ fusion protein modulates NF-κB signaling by sequestering P65/RelA into aggregates.
Zhang XL, Jiang LL, Duan HT, Hu HY
Scientific reports 2025 Jul 27;15(1):27351
Scientific reports 2025 Jul 27;15(1):27351
Pulsed electromagnetic stimulation promotes neuronal maturation by up-regulating cholesterol biosynthesis.
Chen P, Li J, Telezhkin V, Gu Y, Tao M, Guo L, Song S, Dong R, Luo X, Wang Y, Liu Q, Tian W, Meng W, Hong W, Song B
Stem cell research & therapy 2025 Jul 26;16(1):406
Stem cell research & therapy 2025 Jul 26;16(1):406
Liraglutide attenuates autoimmune myocarditis by inhibiting NLRP3 and NF-κb pathways.
Zhang L, Han L, Lu Y, Chen Q
Scientific reports 2025 Jul 26;15(1):27274
Scientific reports 2025 Jul 26;15(1):27274
A missense mutation in TCFL5 is associated with male infertility due to oligoasthenoteratozoospermia.
Yu K, Zhang W, Wang Y, Xiang M, Zheng N, Zhang J, Zha X, Duan Z, Wang F, Cao Y, Zhu F
Molecular genetics and genomics : MGG 2025 Jul 25;300(1):72
Molecular genetics and genomics : MGG 2025 Jul 25;300(1):72
Jianpi Huayu decoction enhances the antitumor effect of doxorubicin via piezo1-mediated autophagy in hepatocellular carcinoma.
Fang C, Liu S, Zhang S, Zheng H, Fang G, Chen C, Zhang Y, Yao R, Chen X, Luo R, Li J, Zhong C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156908
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156908
Kirenol alleviates cerebral ischemic injury by promoting synaptic plasticity via HDAC2-mediated BDNF expression.
Guo M, Ye Y, Li X, Luo S, Cai H, Hong X, Zhang X, Zhang Y, Xu W, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156605
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156605
Discovery of TNI-97 as a Highly Selective, Orally Bioavailable HDAC6 Inhibitor for the Treatment of Triple-Negative Breast Cancer.
Wang S, Luo M, Xu Q, Guo R, Zhang W, Li B, Qin H, Wei L, Cui Y, Sha J, Shao S, Yu X, Zhao L, Sun P, Bai C, Wen J, Liu D
Journal of medicinal chemistry 2025 Jul 24;68(14):14333-14356
Journal of medicinal chemistry 2025 Jul 24;68(14):14333-14356
Sub-chronic realgar exposure causes liver inflammatory injury in mice by inducing bile acid-mediated NLRP3 inflammasome activation through down-regulation of ileal FXR.
Li G, Wang T, Xie Y, He L, Liu H, Chen H, Jiang H, Huo T
Journal of ethnopharmacology 2025 Jul 24;351:120174
Journal of ethnopharmacology 2025 Jul 24;351:120174
Dahuang Huanglian Decoction alleviates dysbiosis by inhibiting GBP5/NLRP3 signaling pathway-mediated pyroptosis of colonic epithelial cells.
Ren T, Yin Y, Zhou X, Chen L, Shen Y, Feng H, Zhou C, Xu Y, Ling Y
Journal of ethnopharmacology 2025 Jul 24;351:120143
Journal of ethnopharmacology 2025 Jul 24;351:120143
Integrating metabolomics and network pharmacology analysis provides new insights into the lipid metabolism disorder of Abrus mollis.
Huang M, Wang X, Lu Y, Zhou Q, Liang J, Li Q, Li L, Fan L
Journal of ethnopharmacology 2025 Jul 24;351:120127
Journal of ethnopharmacology 2025 Jul 24;351:120127
Exploring the mechanism of feiyanning formula and its extract apigenin against EGFR-TKIs resistance in non-small cell lung cancer based on UPLC-HRMS and experimental validation.
Han Y, Jiao L, Zhou H, Sang S, A G, Liu R, Du Y, Wang M, Kang X, Wang Q, Gong Y
Journal of ethnopharmacology 2025 Jul 24;351:120120
Journal of ethnopharmacology 2025 Jul 24;351:120120
Renal tubular GSDME protects cisplatin nephrotoxicity by impeding OGT-STAT3-S100A7A axis in male mice.
Chen Q, Sun P, Zhou J, Long T, Xiao A, Liu Z, Xu S, Lei W, Zhang R, Tian J, Zhou M, Hu Z, Zhu F, Nie J
Nature communications 2025 Jul 24;16(1):6807
Nature communications 2025 Jul 24;16(1):6807
Application of Mendelian randomization and bioinformatic analysis to construct a prognostic model for thyroid cancer and perform pan-cancer analysis.
Zhan Z, Weng Z, Zheng K, Lin J, Yan S, Shen X
Discover oncology 2025 Jul 24;16(1):1402
Discover oncology 2025 Jul 24;16(1):1402
Glucocorticoid-Induced Muscle Satellite Cell-Derived Extracellular Vesicles Mediate Skeletal Muscle Atrophy via the miR-335-5p/MAPK11/iNOS Pathway.
Ma P, Wu J, Zhou R, Xue L, Luo X, Yan Y, Lu J, Dong Y, Geng J, Wang H
Biomolecules 2025 Jul 24;15(8)
Biomolecules 2025 Jul 24;15(8)
Single-cell RNA sequencing analysis revealed the immunosuppressive remodeling of tumor-associated macrophages mediated by the MIF-CD74 axis in gastric cancer.
Liu W, Wang C, Liang L, Zhang C, Li Y, Xiao J, Zeng R, Li J, Lin Z, Huang Q, Zheng L, Zhang Q
Scientific reports 2025 Jul 24;15(1):26883
Scientific reports 2025 Jul 24;15(1):26883
Silver Needle Thermal Therapy Improves Mitochondrial Injury in the Skeletal Muscle of MPS Rats by Inhibiting the TRPV1/CaMKII Pathway.
Huang Y, An S, Tang Y, Yang X, Shen C, Huang Y, Wang L, Wo C
Physiological research 2025 Jul 23;74(3):481-492
Physiological research 2025 Jul 23;74(3):481-492
Trigonelline attenuated sepsis-induced acute kidney injury by activating NAD+/SIRT1 Pathway.
Lv W, Cao D, Yang F
Physiological research 2025 Jul 23;74(3):439-447
Physiological research 2025 Jul 23;74(3):439-447
Divergent Mechanisms of H2AZ.1 and H2AZ.2 in PRC1-Mediated H2A Ubiquitination.
Shen X, Chen C, Jones AE, Jian X, Cao G, Wang H
Cells 2025 Jul 23;14(15)
Cells 2025 Jul 23;14(15)
Injectable thermosensitive hydrogel-encapsulated paclitaxel liposomes enriched with miR-455-3p antagomir for dormancy therapy of salivary adenoid cystic carcinoma.
Li M, Zhang X, Zhang LH, Wang JR, Fan HY, Dou ZC, Liang XH, Tang YL
Journal of materials chemistry. B 2025 Jul 23;13(29):8749-8766
Journal of materials chemistry. B 2025 Jul 23;13(29):8749-8766
MiR-1976 affects lung squamous cell carcinoma development by targeting NCAPH.
Li Y, Zhou H, Yao Y, Fan Z
Journal of applied genetics 2025 Jul 23;
Journal of applied genetics 2025 Jul 23;
Heat shock protein 90 chaperone activity is required for hepatitis A virus replication.
Li Y, Zheng X, Xie L, Kapustina M, Shirasaki T, Yonish B, Chen X, Hirai-Yuki A, Nagata N, Suzuki R, Isogawa M, Vogt MR, Muramatsu M, Lemon SM
Journal of virology 2025 Jul 22;99(7):e0050225
Journal of virology 2025 Jul 22;99(7):e0050225
Zika virus non-structural protein NS2A mediated endoplasmic reticulum stress through interacting with Sarco/endoplasmic reticulum Ca(2+)-ATPase 2.
Wang S, Tang S, Zhou Y, An Q, Du M, Yang X, Zou P, Tang L, Yu Y
Journal of virology 2025 Jul 22;99(7):e0040525
Journal of virology 2025 Jul 22;99(7):e0040525
TRIM56 enhances adenoviral E1A steady state to improve oncolytic adenovirus therapy efficacy.
Sun N, Zhang J, Zhang C, Yin H, Zou B, Geng Y, Gao W, Zhang Y, Wang G, Zheng J, Fang L
Journal of virology 2025 Jul 22;99(7):e0004125
Journal of virology 2025 Jul 22;99(7):e0004125
Tyrosine kinase inhibitors induce cardiotoxicity by causing Ca(2+) overload through the inhibition of phosphoinositide 3-kinase activity.
Gao M, Cheng Z, Yan W, Zhang Z, Zhang L, Geng H, Xu Y, Li C
Biochemical and biophysical research communications 2025 Jul 22;771:152027
Biochemical and biophysical research communications 2025 Jul 22;771:152027
TGF-β/snail-mediated epithelial-to-mesenchymal transition disrupts estradiol metabolism through suppressing the HSD17B2 expression in endometriotic epithelial cells.
Jin P, Cai J, Chen N, Liu Y, Zhao H, Wang Y, Chen J, Li M, Xiao T, Shan C, Yu M, Zhang JV
Biochemical and biophysical research communications 2025 Jul 22;771:151964
Biochemical and biophysical research communications 2025 Jul 22;771:151964
Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastoma.
Aloisi S, Santulli M, Russo M, Zadran SK, Rigamonti A, Chin DH, Palombo M, Cimadom L, Scrofani L, Bernardoni R, Capranico G, Gryder BE, Perini G, Milazzo G
Cell reports 2025 Jul 22;44(7):115951
Cell reports 2025 Jul 22;44(7):115951
APG-115 Induces SLC7A11-Mediated Ferroptosis and Upregulates PD-L1 Expression in Thyroid Cancer.
Liang L, Chen Z, Lei D, Mo C, Lan D, Ke J, Wang W, Yang Z, Guo X, Chen D, Zhao Y, Chen H
ACS omega 2025 Jul 22;10(28):31099-31107
ACS omega 2025 Jul 22;10(28):31099-31107
Disruption of Acetyl-CoA Acyltransferase 2 Resulting from Exposure to Diosbulbin B.
Jiang Y, Tan R, Yang H, Gong B, Wang X, Zhang S, Yang D, Ye T, Hu Z, Peng Y, Li W, Zheng J
Chemical research in toxicology 2025 Jul 21;38(7):1203-1214
Chemical research in toxicology 2025 Jul 21;38(7):1203-1214
C20orf27 promotes hepatocellular carcinoma progression via NT5E.
He Y, Zhang W, Chang M, Chen Y, Lin R, Ye X, Mao W, Lu Y, Lu Y, Chen E
Discover oncology 2025 Jul 21;16(1):1379
Discover oncology 2025 Jul 21;16(1):1379
The p.W651fsX666 mutation on COL10A1 results in impaired trimerization of normal collagen X to induce Schmid type Metaphyseal chondrodysplasia.
Yang J, Zhang J, Lu Q, Tian H, Wang K, Liu Z, Xiong Y, Li Y, Ma N, Tian H, Zhou Z, Zhou D
Human molecular genetics 2025 Jul 20;34(15):1265-1285
Human molecular genetics 2025 Jul 20;34(15):1265-1285
Bio-engineered microRNA-7 effectively interferes with the Akt3/p53 axis to suppress human non-small cell lung cancer.
Huang Q, Chu X, Yang C, Huai Y, He C, Ma X, Pei J, Gao J, Liu Z, Jiang S, Qian A, Tian Y
Cancer cell international 2025 Jul 2;25(1):250
Cancer cell international 2025 Jul 2;25(1):250
Antitumor effects of human antithymocyte globulin on peripheral T cell lymphoma via complement-dependent and -independent cytotoxicity in xenograft mouse models.
Gao BB, Zhang TQ, Zhang JJ, Wang HN, Huang D, Zhang XH, Kang ZJ, Yang Y, Liu XL, Sun C, Shao J, Yan JS
Clinical and experimental medicine 2025 Jul 2;25(1):231
Clinical and experimental medicine 2025 Jul 2;25(1):231
Mesenchymal Stem Cell Protection and Chondrogenic Differentiation in Tracheal Fistula Therapy via Bioactive Platinum Nanozymes.
Shi L, Ji W, Zheng Q, Chen X, Shen H, Zhang G, He S, Chen W, Zeng YM
ACS applied materials & interfaces 2025 Jul 2;17(26):37792-37805
ACS applied materials & interfaces 2025 Jul 2;17(26):37792-37805
Mitochondrial pyruvate carrier inhibits tumor growth by Bmi1 ubiquitination in renal cell carcinoma progression.
Jian D, Hu N, He R, He L, Xiao H, Peng X, Peng Y, Yang Y, Dai X, Wang D, Feng Y, Dai N, Chen Q
Discover oncology 2025 Jul 2;16(1):1253
Discover oncology 2025 Jul 2;16(1):1253
Integrated analyses to explore the mechanism of Gancao Renshen Zhixue Decoction in treating liver cirrhosis.
Pan J
Scientific reports 2025 Jul 2;15(1):23496
Scientific reports 2025 Jul 2;15(1):23496
Exploring the molecular mechanisms of comorbidity between thyroid cancer and breast cancer through multi-omics data.
Yang R, Li J, Zhang H, Liu H, Lian B, Li J
Scientific reports 2025 Jul 2;15(1):23309
Scientific reports 2025 Jul 2;15(1):23309
Identification and verification of oxidative stress-related genes in the diagnosis of osteoporosis.
Liu Z, Yang X, Wang Z, Li Q, Gu H, Meng Q, Zhang Y
Scientific reports 2025 Jul 2;15(1):23222
Scientific reports 2025 Jul 2;15(1):23222
CXCL12/CXCR4 modulates macrophage efferocytosis to induce glomerular crescent formation and fibrosis via ELMO1/DOCK180/RAC1 signaling in ANCA-associated glomerulonephritis.
Liu Z, Deng Y, Song X, Cai X, Xiong H, Tan L, Wei S, Li Q, Wang X, Jiang W, Chen Y, Li Q, Wang M
Cellular and molecular life sciences : CMLS 2025 Jul 19;82(1):280
Cellular and molecular life sciences : CMLS 2025 Jul 19;82(1):280
Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer's disease-like pathology and cognitive decline.
Kong L, Li J, Gao L, Zhao Y, Chen W, Wang X, Wang S, Wang F
Alzheimer's research & therapy 2025 Jul 19;17(1):166
Alzheimer's research & therapy 2025 Jul 19;17(1):166
NR4A1 Mediates Bronchopulmonary Dysplasia-Like Lung Injury Induced by Intrauterine Inflammation in Mouse Offspring.
Ding X, Li R, Yao D, Lei Z, Li W, Shen Q, Chen Z, Ni M, Li B, Liu X, Zhao J, Zhang Q, Liu Z
International journal of molecular sciences 2025 Jul 18;26(14)
International journal of molecular sciences 2025 Jul 18;26(14)
Tryptophan-Rich Diet Improves High-Fat Diet-Induced Cognitive Dysfunction and Blood-Brain Barrier Disruption in C57BL/6 Mice through FFAR3 Activation.
Pan C, Wang J, Mao Z, Jiang X, Xu Y, Zhang Y, Chen L, Zhang ZY, Wang X
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17696-17712
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17696-17712
Blocking or knockdown of P2X7 receptor inhibits invasion and migration of mouse breast cancer cells via PI3K/Akt/GSK-3β pathways and EMT.
Zhao R, Xue Y, Cao Y, Yan M, Li X, Song W, Wang K, Qiao C, Du Y, Peng X
Medical oncology (Northwood, London, England) 2025 Jul 16;42(8):340
Medical oncology (Northwood, London, England) 2025 Jul 16;42(8):340
Agrocybe cylindracea Polysaccharides Ameliorate DSS-Induced Colitis by Restoring Intestinal Barrier Function and Reprogramming Immune Homeostasis via the Gut-Liver Axis.
Atta A, Naveed M, Rahman MU, Alioui Y, Ansari I, Ali S, Ghaleb E, Farooqui NA, Abusidu M, Xin Y, Feng B
International journal of molecular sciences 2025 Jul 16;26(14)
International journal of molecular sciences 2025 Jul 16;26(14)
Chlorella pyrenoidosa Polysaccharide CPP-3a Promotes M1 Polarization of Macrophages via TLR4/2-MyD88-NF-κB/p38 MAPK Signaling Pathways.
Pi Y, Yuan Q, Qin S, Lan C, Nong Q, Yun C, Tang H, Leng J, Xiao J, Zhao L, Zhang L
Marine drugs 2025 Jul 16;23(7)
Marine drugs 2025 Jul 16;23(7)
Modeling oxaliplatin resistance in colorectal cancer reveals a SERPINE1-based gene signature (RESIST-M) and therapeutic strategies for pro-metastatic CMS4 subtype.
Wong SQR, Das M, Tenzin K, Shirgaonkar N, Chua H, Chee LX, Sae Yeoh A, Murugiah AA, Chua WY, Theardy MS, Subel EJ, Thangavelu MT, Chan JV, Yap CK, Tan IBH, Tsantoulis P, Tejpar S, Loo JM, DasGupta R
Cell death & disease 2025 Jul 16;16(1):529
Cell death & disease 2025 Jul 16;16(1):529
SOX4 promotes triple-negative breast cancer progression by promoting SRPX2 transcription to regulate AKR1C1.
Ge W, Shi C, Ge C, Zhang S, Chen S, Qian J
Journal of molecular histology 2025 Jul 15;56(4):226
Journal of molecular histology 2025 Jul 15;56(4):226
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Tu Y, Xiong Y, Liu O, Peng Y
Experimental cell research 2025 Jul 15;450(2):114658
Experimental cell research 2025 Jul 15;450(2):114658
LncRNA USP2-AS1 facilitates colorectal cancer development through the PHLDA2/PI3K/AKT axis.
Zhu J, Lin S, Chang L, Luo Q, Qian M, Ding J, Li J, Pu J, Wang K
Experimental cell research 2025 Jul 15;450(2):114649
Experimental cell research 2025 Jul 15;450(2):114649
Tumor-intrinsic ENO1 inhibition promotes antitumor immune response and facilitates the efficacy of anti-PD-L1 immunotherapy in bladder cancer.
Shen C, Liu J, Hu D, Liu C, Xie F, Wang Y
Journal of experimental & clinical cancer research : CR 2025 Jul 15;44(1):207
Journal of experimental & clinical cancer research : CR 2025 Jul 15;44(1):207
Blocking calcium-MYC regulatory axis inhibits early dedifferentiation of chondrocytes and contributes to cartilage regeneration.
Wu X, Fu Y, Ma J, Wang H, Li C, Zhu Y, Wang Q, Guo X, Zhang T, He A
Stem cell research & therapy 2025 Jul 15;16(1):372
Stem cell research & therapy 2025 Jul 15;16(1):372
Exosomes derived from ALR-modified adipose mesenchymal stem cells mediate hepatoprotective effects on hepatic ischemia-reperfusion injury by promoting regeneration and protecting mitochondria.
Ma Y, Liu T, Li P, Cao L, Lu X, Wang H
Stem cell research & therapy 2025 Jul 15;16(1):361
Stem cell research & therapy 2025 Jul 15;16(1):361
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Xiao S, Wei T, Xiao M, Shan M, An Z, Li N, Zhou J, Zhao S, Lu X
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
Luo W, Zou Y, Jiang Y, Ma X, Guo S, Wang Y, Liu Y, Hai L, Jia W, Liu W, Meng R, Cao X, Ruan X, Yu Y
Cancer research and treatment 2025 Jul 14;
Cancer research and treatment 2025 Jul 14;
The Antidiabetic Mechanisms of Cinnamon Extract: Insights from Network Pharmacology, Gut Microbiota, and Metabolites.
Wang R, Yang K, Liu X, Zhang Y, Chen Y, Wang N, Yu L, Liu S, Hu Y, Qin B
Current issues in molecular biology 2025 Jul 12;47(7)
Current issues in molecular biology 2025 Jul 12;47(7)
Near-infrared organic nanoparticles (6BQ NPs) enhance the random flaps survival by modulating the HSP90/HIF-1α axis through mild photothermal therapy.
Wu F, Zhang J, Ye J, Wang J, Zheng W, Chen H, Dong X, Huang ZS, Cai L, Xiang G
Journal of nanobiotechnology 2025 Jul 12;23(1):503
Journal of nanobiotechnology 2025 Jul 12;23(1):503
Identification of hub six interferon alpha response genes and immune cell infiltration characteristics in low-grade glioma.
Zhang X, Song S, Zhou D, Cui H, Xie J
Scientific reports 2025 Jul 12;15(1):25210
Scientific reports 2025 Jul 12;15(1):25210
SPP1 promotes malignant characteristics and drug resistance in hepatocellular carcinoma by activating fatty acid metabolic pathway.
Wang Z, Wang C
Functional & integrative genomics 2025 Jul 11;25(1):151
Functional & integrative genomics 2025 Jul 11;25(1):151
Chronic sleep deprivation induces plasma exosome-derived miR-150-5p downregulation as a novel mechanism involved in Parkinson's disease progression by targeting DCLK1.
Liu L, Liu X, Zhang R, Sun X, Zhang K, Zheng B, Yang R, Yang K, Song G, Zhang Z
Journal of translational medicine 2025 Jul 11;23(1):781
Journal of translational medicine 2025 Jul 11;23(1):781
Artesunate induces ferroptosis in diffuse large B-cell lymphoma cells by targeting PRDX1 and PRDX2.
Liu X, Zeng L, Liu J, Huang Y, Yao H, Zhong J, Tan J, Gao X, Xiong D, Liu L
Cell death & disease 2025 Jul 11;16(1):513
Cell death & disease 2025 Jul 11;16(1):513
TMEM150A overexpression was associated with poor prognosis and cancer progression in glioma verified by comprehensive analysis and cell experiments.
Xu HQ, Zhao D, Xu SH, Mao R, Yang WQ, Han Q
Scientific reports 2025 Jul 11;15(1):25017
Scientific reports 2025 Jul 11;15(1):25017
A Unique Amino Acid, Se-Met, Regulates Autophagy and Inflammation in Pseudomonas aeruginosa Infection in Mice through the PAK1/Akt1/mTOR and NF-κB Signaling Pathway.
Nie Q, Fang Z, Qin J, Wu M, Zhang Y, Ye L, Zhao R, Li Y, Shen L, Wu M
ACS infectious diseases 2025 Jul 11;11(7):1868-1879
ACS infectious diseases 2025 Jul 11;11(7):1868-1879
Identification and analysis of extracellular matrix and epithelial-mesenchymal transition-related genes in idiopathic pulmonary fibrosis by bioinformatics analysis and experimental validation.
Huang X, Yu W, Tian J, Zhang Y, Wei A, Li Y, Chen S
Gene 2025 Jul 10;956:149464
Gene 2025 Jul 10;956:149464
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
Chen H, Li G, Deng L, Li S, Huang S, Lee SM, Nie X, Bian JS
Biological research 2025 Jul 10;58(1):48
Biological research 2025 Jul 10;58(1):48
Transformable albumin-based nanocapsules selectively amplify tumor starvation and disulfidptosis through metabolic deception.
Li Y, Lu Y, Lu W, Zhong N, Li N, Xu Z, Zhang J, Sun H, Wu F, Teng Z, Tang Y, Wang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113739
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113739
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Zhang J, Zhan Y, Deng Z, Chen S, Yang R, Zhang Y, Fu H, Huang Q, Wu J, Gu Y, Xie J
Respiratory research 2025 Jul 10;26(1):238
Respiratory research 2025 Jul 10;26(1):238
Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.
Wen W, Wang R
NPJ precision oncology 2025 Jul 1;9(1):207
NPJ precision oncology 2025 Jul 1;9(1):207
Trim65 mitigates doxorubicin-induced myocardial injury by reducing ferroptosis.
Ma X, Chen W, Hu Z, Xie L, Li Z, Liu H, Li Z, Jiang Z, Huang J, Jiang C, Huang K, Xiao S
Experimental cell research 2025 Jul 1;450(1):114613
Experimental cell research 2025 Jul 1;450(1):114613
Lipopolysaccharide amplifies the endocytosis of circulating exosomes derived from aortic dissection patients by the endothelial cells via a JMJD6 dependent manner.
Sun Q, Xu J, Zhao Y, Yang L, Cui Y
Life sciences 2025 Jul 1;372:123641
Life sciences 2025 Jul 1;372:123641
THBS4 downregulation alters trophoblast function in preeclampsia via the TGF-β1/Smad signaling cascade.
Shi H, Mao Y, Cui J, Ma R, Yang Z, Zhao Y
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C170-C182
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C170-C182
Target inhibition of NAT10-mediated ac4C modification prevents seizure behavior in mice.
Zhang A, Yang J, Wang M, Li Y, Hu T, Xie J, Xu Y, Cao W
Neuropharmacology 2025 Jul 1;272:110415
Neuropharmacology 2025 Jul 1;272:110415
BAIAP2 as a driver of tumor progression in urothelial bladder cancer.
Huang L, Yan D, Ruan H, Lin Q, Qin H
BMC cancer 2025 Jul 1;25(1):1057
BMC cancer 2025 Jul 1;25(1):1057
Platycodin D-mediated METTL16 downregulation promotes docetaxel treatment of prostate cancer by regulating ferroptosis.
Sun C, Sun X, Chen Y, Wu Y, Xiang C, Wu S
BMC cancer 2025 Jul 1;25(1):1042
BMC cancer 2025 Jul 1;25(1):1042
Hsa_circ_0016662 acts as a prognostic biomarker and promotes the progression of hepatocellular carcinoma via autophagy regulation.
Deng G, He Y, Gan B, Liao C, Luo X, Zheng C, Mao L
Journal of translational medicine 2025 Jul 1;23(1):714
Journal of translational medicine 2025 Jul 1;23(1):714
Phosphorylated IRF3 promotes GSDME-mediated pyroptosis through RIPK1/FADD/caspase-8 complex formation during mitotic arrest in ovarian cancer.
Gong W, Zhou D, Xu Q, Wang L, Luo M, Zhang Y, Liao Z, Xiong F, Zhao G, Zhao B, Gao Q, Fang Y
Cell communication and signaling : CCS 2025 Jul 1;23(1):306
Cell communication and signaling : CCS 2025 Jul 1;23(1):306
Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair.
Li Z, Tang X, Yang H, Lu L, Zhang J, Liu Y
Acta biomaterialia 2025 Jul 1;201:171-186
Acta biomaterialia 2025 Jul 1;201:171-186
Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions.
Mu Y, Zhang N, Wei D, Yang G, Yao L, Xu X, Li Y, Xue J, Zhang Z, Chen T
Neural regeneration research 2025 Jul 1;20(7):2116-2128
Neural regeneration research 2025 Jul 1;20(7):2116-2128
A Zinc-Citrate Metal-Organic Framework-Based Adaptable Hydrogen Sulfide Delivery System for Regulating Neuroregeneration Microenvironment in Spinal Cord Injury.
Yao Y, Dong X, Pang Z, Shao J, He Z, Liu K, Hou P, Hu F, Liu W, Huo Y, Wang H, Dai H, Zhang X
ACS nano 2025 Jul 1;19(25):22798-22819
ACS nano 2025 Jul 1;19(25):22798-22819
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1.
Hou D, Hu Y, Yun T, Yu D, Yang G
Brain research 2025 Jul 1;1858:149638
Brain research 2025 Jul 1;1858:149638
GFOD1 regulates oxidative stress-induced damage in ADHD via NF-κB signaling pathway.
Zheng ML, Yang ZH, He B, Sun X, Zhan YT, Shao AQ, Hong YC, Yin CX, Wang MZ, Ba YC, Ye P
Brain research 2025 Jul 1;1858:149605
Brain research 2025 Jul 1;1858:149605
A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.
Fan Y, Wu H, Yin D, Liu Q, Yuan C, Zhong T, Xia B, Xiong L, Li Y, Zeng L, Li Y, Li Y, Tang L
Bioorganic chemistry 2025 Jul 1;161:108547
Bioorganic chemistry 2025 Jul 1;161:108547
In situ cryo-electron tomography reveals the progressive biogenesis of basal bodies and cilia in mouse ependymal cells.
Ma S, Li L, Li Z, Luo S, Liu Q, Du W, Qiu B, Gui M, Zhu X, Guo Q
Nature communications 2025 Jul 1;16(1):5932
Nature communications 2025 Jul 1;16(1):5932
Ultradeep N-glycoproteome atlas of mouse reveals spatiotemporal signatures of brain aging and neurodegenerative diseases.
Fang P, Yu X, Ding M, Qifei C, Jiang H, Shi Q, Zhao W, Zheng W, Li Y, Ling Z, Kong WJ, Yang P, Shen H
Nature communications 2025 Jul 1;16(1):5568
Nature communications 2025 Jul 1;16(1):5568
AGGF1-primed endothelial progenitor cells alleviate ischaemia-reperfusion injury in diabetic hearts.
Li X, Mu S, Huang S, Dai C, Li Y, Li J, Zhong L, Wei M, Wei L, Li Y
Scientific reports 2025 Jul 1;15(1):21803
Scientific reports 2025 Jul 1;15(1):21803
Lactylation associated biomarkers and immune infiltration in aortic dissection.
Ye J, Fu Y, Ke Y, Liu H, Fang S, Lei Y, Mao Y, Yan L, Wang Y
Scientific reports 2025 Jul 1;15(1):21536
Scientific reports 2025 Jul 1;15(1):21536
Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis.
Hu F, Wang X, Wu R, Liu S, Liu H, Dai R
Scientific reports 2025 Jul 1;15(1):21321
Scientific reports 2025 Jul 1;15(1):21321
Pan-cancer analysis of oncogenic role of MAGOH and experiment validation in hepatocellular carcinoma.
Qiu Z, Le Y, Liao Y, Chen X, Xin X, Nie F, Wei X, Wang H, Fang Z
Scientific reports 2025 Jul 1;15(1):21180
Scientific reports 2025 Jul 1;15(1):21180
Effects of Paeoniae Radix Rubra on lowering lipid via bioinformatics and gut microbiome.
Lin Z, Luo H, Pan S, Li Y, Zhou X, Zhao J, Xu X, Li X, Wang Y, Lv G, Lin Z, Lin H, Qi W
Scientific reports 2025 Jul 1;15(1):21117
Scientific reports 2025 Jul 1;15(1):21117
Ferroptosis is involved in the IL-9-induced intestinal barrier injury in sepsis: an experimental animal and translational study.
Sun JK, Huangfu XT, Yin X, Nie S, Deng YH, Ye ZY, Zhou XH, Wang X, Si YN
International journal of surgery (London, England) 2025 Jul 1;111(7):4314-4324
International journal of surgery (London, England) 2025 Jul 1;111(7):4314-4324
Circular RNA circLIMK1-005 promotes the progression of lung adenocarcinoma by interacting with RPA1 protein to activate CDK4 signaling.
Yang X, Liu L, Yu Z, Chen Y, Xu S, Liu M, Wang M, Guo H, Zhang Z, Shan B, Cai S, Pan M, Zhang J, Wang F, Zheng Y
Cell death discovery 2025 Jul 1;11(1):297
Cell death discovery 2025 Jul 1;11(1):297
Serum Pharmacology Combined with Network Pharmacology Reveals the Effects and Mechanisms of Ganmai Dazao Decoction in the Treatment of Depression.
Wei B, Zheng J, Yan X, Zuo T, Xu Y, Hong M
ACS omega 2025 Jul 1;10(25):27598-27616
ACS omega 2025 Jul 1;10(25):27598-27616
IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders.
McDougal MB, Boys IN, De Maria AM, Nakahara E, Schoggins JW
bioRxiv : the preprint server for biology 2025 Jul 1;
bioRxiv : the preprint server for biology 2025 Jul 1;
CBX3 Downregulates HLTF to Activate PI3K/AKT Signaling Promoting Cholangiocarcinoma.
Xie M, Liang H, Mao Y, Yao Y, Tian B
Advanced biology 2025 Jan;9(1):e2400413
Advanced biology 2025 Jan;9(1):e2400413
The N-terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism.
Wang X, Ning C, Cheng X, Wu Z, Wu D, Ding X, Ju C, Zhou Z, Wan L, Zhao W, Shi P
Animal models and experimental medicine 2025 Jan;8(1):114-125
Animal models and experimental medicine 2025 Jan;8(1):114-125
USP21 stabilizes immune checkpoint of CD276 and serves as an immunological and tumor prognostic biomarker.
Yu Z, Dong C, Yang Y, Zheng Z, Ge X
Biochemical and biophysical research communications 2025 Jan;745:151221
Biochemical and biophysical research communications 2025 Jan;745:151221
Network pharmacology, molecular docking, and experimental verification to reveal the mechanism of colquhounia root tablet in the treatment of diabetic nephropathy.
Chen D, Wang S, Sun Z, Zhang X, Chong N, Shu J, Wang Q, Xu Y
Biochemical and biophysical research communications 2025 Jan;745:151086
Biochemical and biophysical research communications 2025 Jan;745:151086
Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis.
Luo X, Zhang N, Liu Y, Du B, Wang X, Zhao T, Liu B, Zhao S, Qiu J, Wang G
Science China. Life sciences 2025 Jan;68(1):103-115
Science China. Life sciences 2025 Jan;68(1):103-115
In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor.
Xing H, Rosenkranz RRE, Rodriguez-Aliaga P, Lee TT, Majtner T, Böhm S, Turoňová B, Frydman J, Beck M
Nature 2025 Jan;637(8047):983-990
Nature 2025 Jan;637(8047):983-990
Human HDAC6 senses valine abundancy to regulate DNA damage.
Jin J, Meng T, Yu Y, Wu S, Jiao CC, Song S, Li YX, Zhang Y, Zhao YY, Li X, Wang Z, Liu YF, Huang R, Qin J, Chen Y, Cao H, Tan X, Ge X, Jiang C, Xue J, Yuan J, Wu D, Wu W, Jiang CZ, Wang P
Nature 2025 Jan;637(8044):215-223
Nature 2025 Jan;637(8044):215-223
Knockdown of DJ-1 Exacerbates Neuron Apoptosis Induced by TgCtwh3 through the NF-κB Pathway.
Yang D, Wu M, Zou N, Tang Y, Tao Q, Liu L, Jin M, Yu L, Du J, Luo Q, Shen J, Chu D, Qin K
Molecular neurobiology 2025 Jan;62(1):123-136
Molecular neurobiology 2025 Jan;62(1):123-136
Mechanism Analysis of Selenium-Containing Compounds in Alleviating Spinal Cord Injury Based on Network Pharmacology and Molecular Docking Technology.
Han W, Xie L, Ding C, Dai D, Wang N, Ren J, Chen H, Zhu S, Xiao J, Xu H
Molecular neurobiology 2025 Jan;62(1):1031-1046
Molecular neurobiology 2025 Jan;62(1):1031-1046
H1N1 swine influenza viruses upregulate NEU1 expression through histone H3 acetylation regulated by HDAC2.
Zhao Q, Zhang J, Yang S, Bai X, Li Y, Zhang W, Zhang X
Virology 2025 Jan;601:110305
Virology 2025 Jan;601:110305
27-Hydroxycholesterol contributes to hypercholesterolemia-associated aggravation of apical periodontitis in ovariectomized rats and raloxifene counteracts its action.
Wang HW, Yang CN, Kok SH, Hong CY, Shun CT, Lai EH, Cheng SJ, Lin HY, Wu FY, Lin SK
International endodontic journal 2025 Jan;58(1):97-110
International endodontic journal 2025 Jan;58(1):97-110
Dapagliflozin restores autophagy and attenuates apoptosis via the AMPK/mTOR pathway in diabetic nephropathy rats and high glucose-induced HK-2 cells.
Ye YY, Chen Y, Yang J, Wu J, Wang P
International urology and nephrology 2025 Jan;57(1):249-261
International urology and nephrology 2025 Jan;57(1):249-261
KDM2A and KDM2B protect a subset of CpG islands from DNA methylation.
Liu Y, Liu Y, Zhu Y, Hu D, Nie H, Xie Y, Sun R, He J, Zhang H, Lu F
Journal of genetics and genomics = Yi chuan xue bao 2025 Jan;52(1):39-50
Journal of genetics and genomics = Yi chuan xue bao 2025 Jan;52(1):39-50
m6A methyltransferase METTL3 promotes non-small-cell lung carcinoma progression by inhibiting the RIG-I-MAVS innate immune pathway.
Huang T, Ao X, Liu J, Sun C, Dong Y, Yin X, Zhang Y, Wang X, Li W, Cao J, Pan F, Hu Z, Guo Z, He L
Translational oncology 2025 Jan;51:102230
Translational oncology 2025 Jan;51:102230
Niraparib perturbs autophagosome-lysosome fusion in pancreatic ductal adenocarcinoma and exhibits anticancer potential against gemcitabine-resistant PDAC.
Yao Z, Zhang H, Huang K, Huang G, Xi P, Jiang L, Qin D, Chen F, Li S, Wei R
Translational oncology 2025 Jan;51:102206
Translational oncology 2025 Jan;51:102206
Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.
Hu R, Huang Y, Liu Z, Dong H, Ma W, Song K, Xu X, Wu X, Geng Y, Li F, Zhang M, Song Y
Reproductive biomedicine online 2025 Jan;50(1):104296
Reproductive biomedicine online 2025 Jan;50(1):104296
Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma.
Nan N
Toxicology and applied pharmacology 2025 Jan;494:117181
Toxicology and applied pharmacology 2025 Jan;494:117181
P21-activated kinase-1 signaling is required to preserve adipose tissue homeostasis and cardiac function.
Munoz M, Solis C, McCann M, Park J, Rafael-Clyke K, Chowdhury SAK, Jiang Y, Rosas PC
Molecular and cellular biochemistry 2025 Jan;480(1):249-263
Molecular and cellular biochemistry 2025 Jan;480(1):249-263
Spermidine Recovers the Autophagy Defects Underlying the Pathophysiology of Cell Trafficking Disorders.
Díaz-Osorio Y, Gimeno-Agud H, Mari-Vico R, Illescas S, Ramos JM, Darling A, García-Cazorla À, Oyarzábal A
Journal of inherited metabolic disease 2025 Jan;48(1):e12841
Journal of inherited metabolic disease 2025 Jan;48(1):e12841
Esculetin facilitates post-stroke rehabilitation by inhibiting CKLF1-mediated neutrophil infiltration.
He JQ, Yuan RL, Jiang YT, Peng Y, Ye JR, Wang SS, Li LQ, Ruan Y, Li PY, Yan X, He WB, Li G, Chu SF, Zhang Z, Chen NH
Acta pharmacologica Sinica 2025 Jan;46(1):52-65
Acta pharmacologica Sinica 2025 Jan;46(1):52-65
Downregulated YTHDF2 expression in systemic lupus erythematosus is associated with inflammatory and neutrophil cytokine production.
Zhao H, Lan M, Huang Z, Fu P, Fu B, Guo Y, Li J, Luo Q
Clinical rheumatology 2025 Jan;44(1):237-246
Clinical rheumatology 2025 Jan;44(1):237-246
CARD11-BCL10-MALT1 Complex-Dependent MALT1 Activation Facilitates Myocardial Oxidative Stress in Doxorubicin-Treated Mice via Enhancing k48-Linked Ubiquitination of Nrf2.
Lu LQ, Li MR, Liu XY, Peng D, Liu HR, Zhang XJ, Luo XJ, Peng J
Antioxidants & redox signaling 2025 Jan;42(1-3):115-132
Antioxidants & redox signaling 2025 Jan;42(1-3):115-132
ARC protects cochlear hair cells from neomycin-induced ototoxicity via the Ras/JNK signaling pathway.
Yu X, Gao H, Zhang J, Fang Q, Kang W, Shang H, Lou X, Guan M
Toxicology letters 2025 Jan;403:111-119
Toxicology letters 2025 Jan;403:111-119
Maternal Bisphenol A Exposure Induces Hippocampal-Dependent Learning and Memory Deficits Through the PI3K/Akt/mTOR Pathway in Male Offspring Rats.
Ren J, Bai W, Guo Y, Liu Q, Wang Y, Wang C
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70100
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70100
Impact of an extended light regimen imposed during nursery period on the performance and lipid metabolism of weanling pigs.
Liu G, Su F, Zou X, Yang X, Tian L
Animal bioscience 2025 Jan;38(1):176-188
Animal bioscience 2025 Jan;38(1):176-188
Electroacupuncture Pretreatment Reduces Ischemic Brain Injury by Inhibiting the Lactate Production and Its Derived Protein Lactylation Formation.
Pan XR, Zhang YD, Gan YH, Zhang JH, Gao SJ, Feng XS, Xie JX, Wang YF, Zhang XX, Wang PF, Yu SG, Tang Y, Xiong XY
CNS neuroscience & therapeutics 2025 Jan;31(1):e70231
CNS neuroscience & therapeutics 2025 Jan;31(1):e70231
SLC7A5 regulates tryptophan uptake and PD‑L1 expression levels via the kynurenine pathway in ovarian cancer.
Jiang R, Jin B, Sun Y, Chen Z, Wan D, Feng J, Ying L, Peng C, Gu L
Oncology letters 2025 Jan;29(1):26
Oncology letters 2025 Jan;29(1):26
Acute heat stress regulates estradiol synthesis in ovine ovarian granulosa cells through the SREBPs/MVK-LHR pathway.
Li Y, Li F, Shu J, Meng C, Zhang J, Zhang J, Qian Y, Wang H, Ding Q, Cao S
Animal reproduction science 2025 Jan;272:107649
Animal reproduction science 2025 Jan;272:107649
Cetirizine platinum(IV) complexes with antihistamine properties inhibit tumor metastasis by suppressing angiogenesis and boosting immunity.
Chen Y, Feng S, Zhang M, Li S, Zhang N, Han J, Liu Z, Liu M, Wang Q
Journal of inorganic biochemistry 2025 Jan;262:112766
Journal of inorganic biochemistry 2025 Jan;262:112766
Effect of calcium concentration on metastasis of hepatocellular carcinoma cells cultured in alginate gel beads.
Jia Y, Xu X, Liu Y, Shen H, Sun S, Sun G
Colloids and surfaces. B, Biointerfaces 2025 Jan;245:114201
Colloids and surfaces. B, Biointerfaces 2025 Jan;245:114201
CaMKIIα-TARPγ8 signaling mediates hippocampal synaptic impairment in aging.
JianHua Z, Li M, Hu Q, Donoghue P, Jiang S, Li J, Li S, Ren X, Zhang Z, Du J, Yu Y, Chazot P, Lu C
Aging cell 2025 Jan;24(1):e14349
Aging cell 2025 Jan;24(1):e14349
Co-exposure to Environmentally Relevant Levels of Molybdenum and Cadmium Induces Oxidative Stress and Ferroptosis in the Ovary of Ducks.
Wang D, Zhang C, Guo H, Cui T, Pu W, Huang B, Zhu J, Dai X
Biological trace element research 2025 Jan;203(1):374-383
Biological trace element research 2025 Jan;203(1):374-383
Integrin α2β1 deficiency enhances osteogenesis via BMP-2 signaling for accelerated fracture repair.
Kronenberg D, Brand M, Everding J, Wendler L, Kieselhorst E, Timmen M, Hülskamp MD, Stange R
Bone 2025 Jan;190:117318
Bone 2025 Jan;190:117318
PIEZO1 mediates matrix stiffness-induced tumor progression in kidney renal clear cell carcinoma by activating the Ca(2+)/Calpain/YAP pathway.
Zhu B, Li F, Yu J, Liang Z, Ke X, Wang Y, Song Z, Li Z, Li G, Guo Y
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119871
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119871
De novo interleukin-10 production primed by Lactobacillus sakei CVL-001 amplifies the immunomodulatory abilities of mesenchymal stem cells to alleviate colitis.
Nguyen PT, Seo Y, Ahn JS, Oh SJ, Park HJ, Yu JH, Kim SH, Lee Y, Yang JW, Cho J, Kang MJ, Park JH, Kim HS
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jan;182:117745
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jan;182:117745
The important role of the Wnt/β-catenin signaling pathway in small molecules mediated gingival mesenchymal stem cells transdifferentiate into neuron-like cells.
Liang Q, Zhang C, Lv P, Huang Y, Zhao H, Jiang S, Xu W
Archives of oral biology 2025 Jan;169:106115
Archives of oral biology 2025 Jan;169:106115
Melanoma-inhibiting activity promotes the migration and odontoblastic differentiation of stem cells of apical papilla.
Ren H, Zhao Q, Wang N, Yuan X, Song R, Wen Q, Zhao Y
Archives of oral biology 2025 Jan;169:106109
Archives of oral biology 2025 Jan;169:106109
Hepatocyte nuclear factor 4α as a sensitive marker for uterine endocervical adenocarcinomas and their precursors.
Noda Y, Tokuyama Y, Sumita W, Kita M, Tsuta K
Human pathology 2025 Jan;155:105714
Human pathology 2025 Jan;155:105714
Wenshen Yiqi Granule Alleviates Chronic Obstructive Pulmonary Disease via the Long Noncoding RNA-XIST/MicroRNA-200c-3p Axis.
Deng H, Zhu S, Yu F, Song X, Jin X, Ding X
Pulmonary circulation 2025 Jan;15(1):e70040
Pulmonary circulation 2025 Jan;15(1):e70040
Targeting of retrovirus-derived Rtl8a/8b causes late-onset obesity, reduced social response and increased apathy-like behaviour.
Fujioka Y, Shiura H, Ishii M, Ono R, Endo T, Kiyonari H, Hirate Y, Ito H, Kanai-Azuma M, Kohda T, Kaneko-Ishino T, Ishino F
Open biology 2025 Jan;15(1):240279
Open biology 2025 Jan;15(1):240279
Disruption of Ferroptosis Inhibition and Immune Evasion with Tumor-Activatable Prodrug for Boosted Photodynamic/Chemotherapy Eradication of Drug-Resistant Tumors.
Bi T, Zhao Q, Wang T, Huang R, Liu B, Liu X, Wang Y, Sun Q, Yang Y, Liu Z
Advanced healthcare materials 2025 Jan;14(2):e2403473
Advanced healthcare materials 2025 Jan;14(2):e2403473
Downregulation of cardiac inflammation via the CaMKII δ/NF-κB pathway in heart failure by Lonicerae Japonicae Flos and Angelicae Sinensis Radix.
Tang J, Li X, Yu X, Wang D, Huang K, Pu H, Yu J, Li S, Wang W, Liu B, Guo S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156326
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156326
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Wang ZQ, Wu ZX, Chen JW, Li HF, Wu HD, Bao JX, Cheng Y, Dai YW, Wang OC, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Li K, Liu H, Li M, Sun M, Peng X, Wu Y, Tian Y, Liu X, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Multi-omics analysis reveals the protective effects of Chinese yam polysaccharide against cisplatin-induced renal interstitial fibrosis.
Wei M, Chen S, Huang Z, Zhang P, Yang Y, Chen S, Wan P, Huang Z, Chen X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156200
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156200
Echinacoside attenuates Klebsiella pneumoniae-induced pneumonia via inhibition of the TLR4/NF-κB signaling.
Zhang M, Zhan M, Song X
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2025 Jan;133(1):e13507
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2025 Jan;133(1):e13507
Psoralen and Isopsoralen Activate Nuclear Factor Erythroid 2-Related Factor 2 Through Interaction With Kelch-Like ECH-Associated Protein 1.
Lv C, Wang S, Sun C, Liu J, Chen Y, Wang C, Yuan C, Qin F, Li T
Food science & nutrition 2025 Jan;13(1):e4768
Food science & nutrition 2025 Jan;13(1):e4768
C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade.
Su Y, Ao X, Long Y, Zhang Z, Zhang M, Zhang Z, Wei M, Shan S, Lu S, Yu Y, Xu B
Cellular signalling 2025 Jan;125:111513
Cellular signalling 2025 Jan;125:111513
Vericiguat enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction through microRNA-1180-3p/ETS1 pathway.
Li C, Zheng C, Pu Y, Zhou H, Li Y, Wang W, Chen X, Zhang C, Chen Y
Cellular signalling 2025 Jan;125:111512
Cellular signalling 2025 Jan;125:111512
CXCL1-CXCR2 signaling mediates the activation of microglia in the nucleus tractus solitarii to promote pancreatic cancer-induced pain.
Chen K, Ye Q, Zhang Y, Qi Z, Huang Y, Lu W, Wang X, Wang Y, Cao L, Qiu S, Xu Y, Huang J, Xie J
Brain, behavior, and immunity 2025 Jan;123:1026-1041
Brain, behavior, and immunity 2025 Jan;123:1026-1041
Cytoskeletal Vimentin Directs Cell-Cell Transmission of Hepatitis C Virus.
Xing Y, Wen Z, Mei J, Huang X, Zhao S, Zhong J, Jiu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(3):e2408917
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(3):e2408917
Harnessing Tumor Cell-Derived Exosomes for Immune Rejection Management in Corneal Transplantation.
Yang J, Kang H, Liu Y, Lu S, Wu H, Zhang B, He Y, Zhou W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(2):e2409207
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(2):e2409207
Bioactive Self-Assembled Nanoregulator Enhances Hematoma Resolution and Inhibits Neuroinflammation in the Treatment of Intracerebral Hemorrhage.
Yu W, Che C, Yang Y, Zhao Y, Liu J, Chen A, Shi J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2408647
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2408647
MCM3 promotes hepatocellular carcinoma progression via Epithelial-mesenchymal Transition through AKT/Twist signaling pathway.
Tang WG, Feng JF, Li X, Sun QM, Hu JW, Ma XL, Nie YY, Xu Y, Sun J, Chang QM
Annals of hepatology 2025 Jan-Jun;30(1):101785
Annals of hepatology 2025 Jan-Jun;30(1):101785
Long non-coding RNA LINC01224 plays an oncogenic role in endometrial cancer via miR-4673/TPX2 axis and activating Wnt/β-catenin signaling pathway.
Lv S, Zhang X, Lang F, Wu Y, Zhang C, Qi Q, Jiang J
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2153
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2153
Administration of β-Nicotinamide Mononucleotide Attenuates Myocardial Dysfunction in Tail-Suspended Mice.
Gu W, Liu D, Wei L, Yang Z, Jiang S, Dai S, Cao T, Shen Z
Journal of cardiovascular pharmacology and therapeutics 2025 Jan-Dec;30:10742484251369609
Journal of cardiovascular pharmacology and therapeutics 2025 Jan-Dec;30:10742484251369609
Znhit1 alleviates nitroglycerin-induced hyperalgesia in migraine mice via the inhibition of NOD-like receptor signaling pathway.
Wang X, Tang J, Hou Y, Sui C
Molecular pain 2025 Jan-Dec;21:17448069251389420
Molecular pain 2025 Jan-Dec;21:17448069251389420
The peripheral PI3K/AKT/MLC signalling pathway alleviates myofascial pain in rats by inhibiting abnormal contraction at myofascial trigger points.
Zhang M, Zhu Y, Jin F, Liu Y, Yin L
Molecular pain 2025 Jan-Dec;21:17448069251376205
Molecular pain 2025 Jan-Dec;21:17448069251376205
Targeting sphingosine-1-phosphate receptor 1 alleviates neuropathic pain associated with pancreatic ductal adenocarcinoma in mice and inhibits tumor progression.
Cai SQ, Zhang YX, Wang C, Gao Y, Wang TY, Xu FN, Liu QZ, Yin J, Zhang ZJ, Zhang S, Duan ML, Huang Y, Tao GJ
Molecular pain 2025 Jan-Dec;21:17448069251371549
Molecular pain 2025 Jan-Dec;21:17448069251371549
Transplantation of engineered endothelial progenitor cells with H19 overexpression promotes arterial reendothelialization and inhibits neointimal hyperplasia.
Ye Y, Huang L, Wang K, Sun Y, Zhou Z, Deng T, Liu Y, Wang R, Wu R, Yao C
Journal of tissue engineering 2025 Jan-Dec;16:20417314251315959
Journal of tissue engineering 2025 Jan-Dec;16:20417314251315959
Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis.
Wang G, Dong Y, Qiao X, Jia C, Wang J, Chen G, Zheng K, Jiang C, Li X
Kidney diseases (Basel, Switzerland) 2025 Jan-Dec;11(1):450-468
Kidney diseases (Basel, Switzerland) 2025 Jan-Dec;11(1):450-468
circ_0075048 silencing regulates LCP1 to improve IL-1β-induced chondrocyte injury by binding with miR-663b.
Zhang P, Pei R, Shen Q
Journal of orthopaedic surgery and research 2025 Jan 9;20(1):24
Journal of orthopaedic surgery and research 2025 Jan 9;20(1):24
5-(3-(N-(Carboxymethyl)naphthalene-2-sulfonamido)phenyl)-1-ethyl-1H-pyrrole-2-carboxylic acid as a Keap1-Nrf2 inhibitor for cerebral ischemia/reperfusion injury treatment.
Cairang N, Wu Y, Zhi S, Tang J, Tie X, Zhan D, Lu G, Shi Y, Zhao Q
RSC advances 2025 Jan 9;15(2):1052-1059
RSC advances 2025 Jan 9;15(2):1052-1059
A novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA.
Li D, Chen Y, Zhu X, Yang Y, Li H, Zhao RC
Journal of biomedical science 2025 Jan 8;32(1):6
Journal of biomedical science 2025 Jan 8;32(1):6
The Effect of Adipose-Derived Stem Cell (ADSC)-Exos on the Healing of Autologous Skin Grafts in Miniature Pigs.
Li P, Cao L, Liu T, Lu X, Ma Y, Wang H
International journal of molecular sciences 2025 Jan 8;26(2)
International journal of molecular sciences 2025 Jan 8;26(2)
CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma.
Yang K, Wang Y, Jian Y, Wang B, Du H, Xia Y, Bi J, Guo M, Li Z, Wang N
Cancer cell international 2025 Jan 8;25(1):8
Cancer cell international 2025 Jan 8;25(1):8
hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p.
Huang S, Liu K, Xu Y, Wang H, Fu S, Wu J
Scientific reports 2025 Jan 8;15(1):1309
Scientific reports 2025 Jan 8;15(1):1309
Inhibition of Endothelial-Mesenchymal Transition Mediated by Activin Receptor Type IIA Attenuates Valvular Injury Induced by Group A Streptococcus in Lewis Rats.
Lu Z, Li Y, Lu C, Meng Z, Bai L, Huang F, Zeng Z
Frontiers in bioscience (Landmark edition) 2025 Jan 7;30(1):26370
Frontiers in bioscience (Landmark edition) 2025 Jan 7;30(1):26370
Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13.
Tan C, Zhou H, Xiong Q, Xian X, Liu Q, Zhang Z, Xu J, Yao H
Respiratory research 2025 Jan 6;26(1):3
Respiratory research 2025 Jan 6;26(1):3
Helicobacter pylori infection promotes M1 macrophage polarization and gastric inflammation by activation of NLRP3 inflammasome via TNF/TNFR1 axis.
Fei X, Chen S, Li L, Xu X, Wang H, Ke H, He C, Xie C, Wu X, Liu J, Xie Y, Lu N, Zhu Y, Li N
Cell communication and signaling : CCS 2025 Jan 6;23(1):6
Cell communication and signaling : CCS 2025 Jan 6;23(1):6
Human DBR1 deficiency impairs stress granule-dependent PKR antiviral immunity.
Ru S, Tang S, Xu H, Yin J, Guo Y, Song L, Jin Z, Lee D, Chan YH, Chen X, Buerer L, Fairbrother W, Jia W, Casanova JL, Zhang SY, Gao D
The Journal of experimental medicine 2025 Jan 6;222(1)
The Journal of experimental medicine 2025 Jan 6;222(1)
Estrogen sulfotransferase SULT1E1 expression correlates with progression and prognosis of lung adenocarcinoma.
Wang R, Zhang W, Wu J, Chen W, Zhao M, Xu Y, Li X, Song J
Scientific reports 2025 Jan 6;15(1):925
Scientific reports 2025 Jan 6;15(1):925
The effects of moderate alcohol and THC co-use during male and female rat adolescence on AKT-GSK3ß signaling in adulthood.
Shi L, Choi CY, Carrica LK, Liang NC, Gulley JM
Behavioural brain research 2025 Jan 5;476:115292
Behavioural brain research 2025 Jan 5;476:115292
Exercise alleviates CUS-induced depressive-like behaviors by modulating paracellular and transcellular permeability of the blood-brain barrier in the prefrontal cortex.
Luo Y, Meng D, Tang H, Wu P, Zhang Y
Behavioural brain research 2025 Jan 5;476:115286
Behavioural brain research 2025 Jan 5;476:115286
Glycerophospholipid metabolic disorders and gender difference of cantharidin-induced hepatotoxicity in rats: Lipidomics and MALDI mass spectrometry imaging analysis.
Wang Q, Cheng W, He T, Li S, Ao J, He Y, Duan C, Li X, Zhang J
Chemico-biological interactions 2025 Jan 5;405:111314
Chemico-biological interactions 2025 Jan 5;405:111314
Aristolochic acid I induced mitochondrial Ca(2+) accumulation triggers the production of MitoROS and activates Src/FAK pathway in hepatocellular carcinoma cells.
Hu Y, Zhang Q, Jiang W, Wang X, Guo X, Chen L, Cheng S, Ying J, Ye J, Zhang L
Chemico-biological interactions 2025 Jan 5;405:111269
Chemico-biological interactions 2025 Jan 5;405:111269
D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint.
Tu CE, Liu YF, Liu HW, Jiao CM, Liu Q, Hung MC, Li P, Wan XB, Fan XJ, Wang YL
Journal of hematology & oncology 2025 Jan 4;18(1):2
Journal of hematology & oncology 2025 Jan 4;18(1):2
Potassium molybdate blocks APN-dependent coronavirus entry by degrading receptor via PIK3C3-mediated autophagy.
Zhang Y, Zhang N, Zhang Y, Li Y, Yang N, Cai Y, Tan C, Zhao J, Li W, Liu Y, Rui X, Wu J, Fu Y, Liu G
Journal of virology 2025 Jan 31;99(1):e0144924
Journal of virology 2025 Jan 31;99(1):e0144924
Identification of viral protease-dependent cleavage sites within the human astrovirus polyprotein.
Mehri S, Bengert B, Holliday M, Corliss L, Prevelige PE, Lennemann NJ
Journal of virology 2025 Jan 31;99(1):e0132124
Journal of virology 2025 Jan 31;99(1):e0132124
Swine RNF5 positively regulates the antiviral activity of IFITM1 by mediating the degradation of ABHD16A.
Shi X, Shen L, Chen S, Liu M, Wang J, Wen X, Liu W, Mao L, Ding Y, Yu L, Xu J
Journal of virology 2025 Jan 31;99(1):e0127724
Journal of virology 2025 Jan 31;99(1):e0127724
Tannic acid reactivates HIV-1 latency by mediating CBX4 degradation.
Chen C, Zhong Z, Zhang W, Xia B, Wu L, Liang L, Zhang Y, Zhang H, Zhang X, Pan T, Li L, Liu B
Journal of virology 2025 Jan 31;99(1):e0117324
Journal of virology 2025 Jan 31;99(1):e0117324
Remimazolam alleviates sleep deprivation induced anxiety-like behaviors via regulating the STING pathway.
Fan J, Feng J, Yang L, Zhang Q, Li H
Neuroscience letters 2025 Jan 31;847:138095
Neuroscience letters 2025 Jan 31;847:138095
The mechanism of exosomes of BMSCs modified with Bu Shen Yi Sui capsule in promoting remyelination via regulating miR-15b/Wnt signaling pathway-mediated differentiation of oligodendrocytes.
Liu SS, Zha Z, Li C, Li CY, Wang L
Journal of ethnopharmacology 2025 Jan 31;340:119283
Journal of ethnopharmacology 2025 Jan 31;340:119283
Centipeda minima extracts and the active sesquiterpene lactones have therapeutic efficacy in non-small cell lung cancer by suppressing Skp2/p27 signaling pathway.
Wang HC, Wu PE, He WD, Chen CY, Zheng RQ, Pang YC, Wu LC, Cheng YX, Liu YQ
Journal of ethnopharmacology 2025 Jan 31;340:119277
Journal of ethnopharmacology 2025 Jan 31;340:119277
Lichong decoction improves inflammatory microenvironment and alleviates fibrosis in uterine leiomyoma via targeting CXCL8.
Yang X, Chen Z, Qiu T, Liu Y, Ren H, Luo W, Zuo J, Li D
Journal of ethnopharmacology 2025 Jan 31;340:119276
Journal of ethnopharmacology 2025 Jan 31;340:119276
Molecular insights into the therapeutic mechanisms of Bushen-Qiangdu-Zhilv decoction for ankylosing spondylitis.
Ma M, Yang Z, Li K, Yang L, Chen B, Chen M, Du H, Zhou Y, He X, He Y
Journal of ethnopharmacology 2025 Jan 31;340:119269
Journal of ethnopharmacology 2025 Jan 31;340:119269
Integrating metabolomics and network pharmacology to investigate Da-Chai-Hu Decoction prevents kidney injury in diabetic mice.
Wang X, Zhong ZJ, Chen PF, Deng CF, Chen XM, Xin GZ, Tang D
Journal of ethnopharmacology 2025 Jan 31;340:119158
Journal of ethnopharmacology 2025 Jan 31;340:119158
Baricitinib represses the myocardial fibrosis via blocking JAK/STAT and TGF-β1 pathways in vivo and in vitro.
Feng R, Liu H, Chen Y
BMC cardiovascular disorders 2025 Jan 31;25(1):65
BMC cardiovascular disorders 2025 Jan 31;25(1):65
Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization.
Xian H, Guo H, Liu YY, Ma SB, Zhao R, Zhang JL, Zhang H, Xie RG, Guo XC, Ren J, Wu SX, Luo C, Cong R
Cell & bioscience 2025 Jan 31;15(1):12
Cell & bioscience 2025 Jan 31;15(1):12
Taxus chinensis (Pilg.) Rehder fruit attenuates aging behaviors and neuroinflammation by inhibiting microglia activation via TLR4/NF-κB/NLRP3 pathway.
Meimei C, Fei Z, Wen X, Huangwei L, Zhenqiang H, Rongjun Y, Qiang Z, Qiuyang L, Xiaozhen L, Yuan Y, Zhaoyang Y, Candong L
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118943
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118943
Exploring the liver toxicity mechanism of Tripterygium wilfordii extract based on metabolomics, network pharmacological analysis and experimental validation.
Zhou GL, Su SL, Yu L, Shang EX, Hua YQ, Yu H, Duan JA
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118888
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118888
Simiao Wan attenuates high-fat diet-induced hyperlipidemia in mice by modulating the gut microbiota-bile acid axis.
Wang K, Xu W, He W, Ding M, Xia T, Tan X
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118868
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118868
Comparison of chemical composition between imitation wild and transplanted Astragali Radix and their therapeutic effects on heart failure.
Zhang C, Zhu Y, Wang M, Chen R, Sun X
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118827
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118827
Extract of Tinospora sinensis alleviates LPS-induced neuroinflammation in mice by regulating TLR4/NF-κB/NLRP3 signaling pathway.
Xie Y, Fang C, Lu L, Wang J, Wu L, Wang S, Guo Q, Yan W, Wei J, Duan F, Huang L
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118807
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118807
Huang-Lian-Jie-Du Decoction alleviates diabetic encephalopathy by regulating inflammation and pyroptosis via suppression of AGEs/RAGE/NF-κB pathways.
Zhuang GD, Deng SM, Chen MD, Deng CF, Gu WT, Wang SM, Tang D
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118787
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118787
Zangsiwei prevents particulate matter-induced lung inflammation and fibrosis by inhibiting the TGF-β/SMAD pathway.
Wu Z, Song B, Peng F, Zhang Q, Wu S
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118752
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118752
Dehydrocorydaline attenuates myocardial ischemia-reperfusion injury via the FoXO signalling pathway: A multimodal study based on network pharmacology, molecular docking, and experimental study.
Li H, Yang W, Shang Z, Lu Y, Shen A, Chen D, Lin G, Li M, Li R, Wu M, Guo Z, Qu H, Fu C, Yu Z, Chen K
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118738
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118738
Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation.
Xu W, Lv S, Wang X, Song C, Xi C, Yan J
Journal of orthopaedic surgery and research 2025 Jan 30;20(1):117
Journal of orthopaedic surgery and research 2025 Jan 30;20(1):117
Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway.
Zhang Z, Zeng Z, Wang L, Xiong B, Zheng B, Zhang Y, Pan L
Journal of the science of food and agriculture 2025 Jan 30;105(2):974-981
Journal of the science of food and agriculture 2025 Jan 30;105(2):974-981
Dual efficacy of tocilizumab in managing PD-1 inhibitors-induced myocardial inflammatory injury and suppressing tumor growth with PD-1 inhibitors: a preclinical study.
Chen Y, Luo Y, Liu Y, Luo D, Liu A
Cancer immunology, immunotherapy : CII 2025 Jan 3;74(2):52
Cancer immunology, immunotherapy : CII 2025 Jan 3;74(2):52
Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway.
Zhang J, Yang S, Chen X, Zhang F, Guo S, Wu C, Wang T, Wang H, Lu S, Qiao C, Sheng X, Liu S, Zhang X, Luo H, Li Q, Wu J
Chinese medicine 2025 Jan 3;20(1):2
Chinese medicine 2025 Jan 3;20(1):2
Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway.
Chen Y, Yang C, Miao Y, Shi D, Li X, Tian S, Zhang Y, Xu C, Dong Y, Han C, Shi H, Bai C
Nature communications 2025 Jan 3;16(1):289
Nature communications 2025 Jan 3;16(1):289
Atractylenolide-III restrains cardiac fibrosis after myocardial infarction via suppression of the RhoA/ROCK1 and ERK1/2 pathway.
Li X, Zhu X, Jiang S, Yang W, Zhang F, Guo X, Wei Y
International immunopharmacology 2025 Jan 3;145:113825
International immunopharmacology 2025 Jan 3;145:113825
Deletion of BRCC3 ameliorates airway inflammation in asthma by inhibiting the activation of NLRP3 inflammasome.
Wang H, Chen Y, Zhang J, Wang N, Tian T
International immunopharmacology 2025 Jan 3;145:113720
International immunopharmacology 2025 Jan 3;145:113720
6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy.
You Q, Wu J, Lyu R, Cai Y, Jiang N, Liu Y, Zhang F, He Y, Chen D, Wu Z
BMC microbiology 2025 Jan 29;25(1):53
BMC microbiology 2025 Jan 29;25(1):53
Enhanced Chondrogenic Potential and Osteoarthritis Treatment Using Cyaonoside A-Induced MSC Delivered via a Hyaluronic Acid-Based Hydrogel System.
An X, Zhou Q, Sheng S, Deng A, Liu H, Wang X, Zhang Q, Jing Y, Xu K, He C, Zhao RC, Su J
Aging and disease 2025 Jan 29;17(1):466-482
Aging and disease 2025 Jan 29;17(1):466-482
Altered mitochondrial unfolded protein response and FGF21 secretion in MASLD progression and the effect of exercise intervention.
Yuan X, Sun W, Xu Y, Xiang M, Gao Y, Feng W, Xiao H, Zhang L, Tang Q, Lu J, Zhang Y
Scientific reports 2025 Jan 29;15(1):3686
Scientific reports 2025 Jan 29;15(1):3686
A Y178C rhodopsin mutation causes aggregation and comparatively severe retinal degeneration.
Vasudevan S, Park PS
Cell death discovery 2025 Jan 29;11(1):32
Cell death discovery 2025 Jan 29;11(1):32
Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway.
Cui F, Deng S, Fu Y, Xu T, Bao S, Wang S, Lin Y, Wang X, Zhao F, Zhang T, Xu S, Zhang Z, Li W, Yang GY, Tang H, Wang J, Sheng X, Tang Y
Cell reports 2025 Jan 28;44(1):115126
Cell reports 2025 Jan 28;44(1):115126
LncRNA-ANRIL regulates CDKN2A to promote malignant proliferation of Kasumi-1 cells.
Xu J, Zhang J, Zhang C, Hu H, Wang S, Deng F, Zhou W, Liu Y, Hu C, Huang H, Wei S
Cell division 2025 Jan 28;20(1):2
Cell division 2025 Jan 28;20(1):2
Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition.
Zhang J, Peng J, Wang S, Wang L, Sun Y, Xia J, Cheng B, Hu Q
Cell death discovery 2025 Jan 28;11(1):30
Cell death discovery 2025 Jan 28;11(1):30
Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome.
Liu Z, Wang RH, Wang KH
Molecular medicine (Cambridge, Mass.) 2025 Jan 27;31(1):27
Molecular medicine (Cambridge, Mass.) 2025 Jan 27;31(1):27
Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway.
Li B, Yu K, Zhou X, Sun J, Qi L, Li W, Yang T, Li W, Wang N, Gu X, Cui S, Cao R
The journal of headache and pain 2025 Jan 27;26(1):16
The journal of headache and pain 2025 Jan 27;26(1):16
Essential oils from Amorpha fruticosa against hepatocellular carcinoma based on network pharmacology.
Liu Y, Zhang X, Hao J, Zhao Y, Zou M, Chen H, Zhang J
BMC complementary medicine and therapies 2025 Jan 27;25(1):29
BMC complementary medicine and therapies 2025 Jan 27;25(1):29
DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway.
Wang H, Luo S, Yin Y, Liu Y, Sun X, Qiu L, Wu X
Cancer cell international 2025 Jan 27;25(1):25
Cancer cell international 2025 Jan 27;25(1):25
Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD.
Xu Y, Zhang Y, Sun W, Tang Q, Feng W, Xiao H, Wang J, Yuan X, Xiang M, Gao Y, Zhang H, Lu J
Scientific reports 2025 Jan 27;15(1):3399
Scientific reports 2025 Jan 27;15(1):3399
An oral vaccine based on the Ad5 vector with a double-stranded RNA adjuvant protects mice against respiratory syncytial virus.
Chai P, Shi Y, Yu J, Liu X, Yang M, Li D, Li K, Li S, Kong X, Zhang Q, Sun X, Li J, Li L, Li D, Duan Z
International immunopharmacology 2025 Jan 27;146:113970
International immunopharmacology 2025 Jan 27;146:113970
Mechanism of S100A9-mediated astrocyte activation via TLR4/NF-κB in Parkinson's disease.
Qiao CM, Tan LL, Ma XY, Xia YM, Li T, Li MA, Wu J, Nie X, Cui C, Zhao WJ, Shen YQ
International immunopharmacology 2025 Jan 27;146:113938
International immunopharmacology 2025 Jan 27;146:113938
STEAP3-SLC39A8-mediated microglia ferroptosis involved in neurotoxicity in rats after exposure to lead and cadmium combined.
Sun Y, Liu J, Xiao K, Chen S, Ma J, Cao M, Yang Y, Shao H, Cui G, Du Z
International immunopharmacology 2025 Jan 27;146:113854
International immunopharmacology 2025 Jan 27;146:113854
Dihydromyricetin ameliorates neurotoxicity induced by high glucose through restraining ferroptosis by inhibiting JNK-inflammation pathway in HT22 cells.
Peng LT, Li MW, Song ZJ, Li Q, Zhan KB, Yan CQ, Ling HY
Neuroscience 2025 Jan 26;565:40-51
Neuroscience 2025 Jan 26;565:40-51
Targeting hyperactive mitochondria in activated HSCs and inhibition of liver fibrogenesis in mice using sorafenib complex micelles.
Xiang L, Qin Y, Li L, Xiang X, Zhang W, Jiao Q, Shao Y, Huang X, Wu M, Zhou T, Lin Y, Chen Y
International journal of pharmaceutics 2025 Jan 25;669:125058
International journal of pharmaceutics 2025 Jan 25;669:125058
Ubiquitin-conjugating enzyme E2T confers chemoresistance of colorectal cancer by enhancing the signal propagation of Wnt/β-catenin pathway in an ERK-dependent manner.
Liu B, Liu R, Zhang X, Tian L, Li Z, Yu J
Chemico-biological interactions 2025 Jan 25;406:111347
Chemico-biological interactions 2025 Jan 25;406:111347
Retinol-Binding Protein 4 as a Biomarker in Cancer: Insights from a Pan-Cancer Analysis of Expression, Immune Infiltration, and Methylation.
Zhao J, Liu Y, Zhou L, Liu Y
Genes 2025 Jan 25;16(2)
Genes 2025 Jan 25;16(2)
The role of cGAS-STING pathway in the development of radiation-induced lung injury.
Zhao X, Du L, Ma N, Tan X, Lei X, Zhang P, Qu B
Journal of cancer research and clinical oncology 2025 Jan 25;151(2):48
Journal of cancer research and clinical oncology 2025 Jan 25;151(2):48
IDO1 inhibits ferroptosis by regulating FTO-mediated m6A methylation and SLC7A11 mRNA stability during glioblastoma progression.
Tian Q, Dan G, Wang X, Zhu J, Chen C, Tang D, Wang Z, Chen D, Lei S, Yang C, Wang H, Guo B, Jin B, Chen T, Tang L
Cell death discovery 2025 Jan 25;11(1):22
Cell death discovery 2025 Jan 25;11(1):22
Manganese exposure induces parkinsonism-like symptoms by Serpina3n-TFEB-v/p-ATPase signaling mediated lysosomal dysfunction.
Hong H, Liu S, Yang T, Lin J, Luo K, Xu Y, Li T, Xi Y, Yang L, Lu YQ, Yuan W, Zhou Z
Cell biology and toxicology 2025 Jan 23;41(1):34
Cell biology and toxicology 2025 Jan 23;41(1):34
Development of Sheep Intestinal Organoids for Studying Deoxynivalenol-Induced Toxicity.
Wang H, He X, Zhang M, Fan N, Yang Z, Shen T, Guo J, Song Y, Cao G, Liu Y, Li X, Nashun B
International journal of molecular sciences 2025 Jan 23;26(3)
International journal of molecular sciences 2025 Jan 23;26(3)
YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies.
Chen Z, Zeng C, Yang L, Che Y, Chen M, Sau L, Wang B, Zhou K, Chen Y, Qing Y, Shen C, Zhang T, Wunderlich M, Wu D, Li W, Wang K, Leung K, Sun M, Tang T, He X, Zhang L, Swaminathan S, Mulloy JC, Müschen M, Huang H, Weng H, Xiao G, Deng X, Chen J
Cell 2025 Jan 23;188(2):331-351.e30
Cell 2025 Jan 23;188(2):331-351.e30
MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma.
Zhou C, Liu J, Hu X, Lu L, Hou J, Wang J, Jiang L, Huang S, Lin Y, Liu L, Cui L, Liu Y, Huang Y
European journal of medical research 2025 Jan 22;30(1):43
European journal of medical research 2025 Jan 22;30(1):43
Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining.
Liu WJ, Shen JP, Zhang RQ, Fan XY
Discover oncology 2025 Jan 22;16(1):78
Discover oncology 2025 Jan 22;16(1):78
YTH N(6)-methyladenosine RNA Binding Protein 1 Inhibits Smooth Muscle Cell Phenotypic Modulation and Neointimal Hyperplasia.
Tian K, Cai D, Yang S, Zhao W, Mei X, Chen SY
Cells 2025 Jan 22;14(3)
Cells 2025 Jan 22;14(3)
Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis.
Zeng Y, Wu Z, Xiong M, Liang Z, Chen Z, Huang H, Yang H, Chen Q
Communications biology 2025 Jan 21;8(1):96
Communications biology 2025 Jan 21;8(1):96
1-methyl-tryptophan improves anxiety-like behavior in colitis mice by inhibiting neuroinflammation, promoting cell regeneration, and decreasing apoptosis.
Zhao LP, Tan LL, Xia YM, Ma XY, Li T, Zhou SY, Wu J, Li MA, Zhao WJ, Shen YQ
Clinical and experimental immunology 2025 Jan 21;219(1)
Clinical and experimental immunology 2025 Jan 21;219(1)
Docosahexaenoic acid mitigates experimental autoimmune prostatitis by inhibiting Th17 cell differentiation via the PPARγ/NF-κB/IL-17A pathway.
Wu W, Yue S, Wang X, Li W, Xu L, Guan Y, Liang CZ
Clinical and experimental immunology 2025 Jan 21;219(1)
Clinical and experimental immunology 2025 Jan 21;219(1)
PKM2-mediated collagen XVII expression is critical for wound repair.
Liu Y, Ho C, Wen D, Sun J, Liu Y, Li Q, Zhang Y, Gao Y
JCI insight 2025 Jan 21;10(4)
JCI insight 2025 Jan 21;10(4)
Maternal exposure to fullerenols impairs placental development in mice by inhibiting estriol synthesis and reducing ERα.
He Q, Yuan J, Yang H, Du T, Hu S, Ding L, Yan W, Chen P, Li J, Huang Z
Journal of nanobiotechnology 2025 Jan 20;23(1):30
Journal of nanobiotechnology 2025 Jan 20;23(1):30
Peroxiredoxin 6 maintains mitochondrial homeostasis and promotes tumor progression through ROS/JNK/p38 MAPK signaling pathway in multiple myeloma.
Gao D, Lv Y, Hong F, Wu D, Wang T, Gao G, Lin Z, Yang R, Hu J, He A, Zhang P
Scientific reports 2025 Jan 2;15(1):70
Scientific reports 2025 Jan 2;15(1):70
Lidocaine Enhanced Antitumor Efficacy and Relieved Chemotherapy-Induced Hyperalgesia in Mice with Metastatic Gastric Cancer.
Gao P, Peng F, Liu J, Wu W, Zhao G, Liu C, Cao H, Li Y, Qiu F, Zhang W
International journal of molecular sciences 2025 Jan 19;26(2)
International journal of molecular sciences 2025 Jan 19;26(2)
Both 20S and 19S proteasome components are essential for meiosis in male mice.
Han TT, Wang LY, Zhou QX, Wei W, Ma YJ, Chen YH, Li W, Ju ZY, Liu C
Zoological research 2025 Jan 18;46(1):27-40
Zoological research 2025 Jan 18;46(1):27-40
piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1.
Yuan J, Xie BM, Ji YM, Bao HJ, Wang JL, Cheng JC, Huang XC, Zhao Y, Chen S
Cell death & disease 2025 Jan 18;16(1):25
Cell death & disease 2025 Jan 18;16(1):25
Oxymatrine relieves non-alcoholic fatty liver disease by promoting sirtuin 1/adenosine 5'-monophosphate-activated protein kinase pathway and peroxisome proliferator activated receptor alpha-mediated hepatic fatty acid oxidation.
Wu Y, Xiong J, Chen G, Liu Y, Zhao C, Zhang Z, Xu H
European journal of pharmacology 2025 Jan 15;987:177173
European journal of pharmacology 2025 Jan 15;987:177173
FHOD3 shows clinical significance in progression of ovarian cancer through regulation of caspase-3 signaling pathway.
Huang Y, Zhang Y, Shen Z, Xu J, Sheng J
Gene 2025 Jan 15;933:148943
Gene 2025 Jan 15;933:148943
TESC overexpression mitigates amyloid-β-induced hippocampal atrophy and memory decline.
Qi J, Suo X, Tian C, Xia X, Qin W, Wang P, Tang J, Xu J, Fu J, Liu N, Yu C, Shen H, Dou Y
Gene 2025 Jan 15;933:148939
Gene 2025 Jan 15;933:148939
Umbilical cord mesenchymal stem cell-derived exosomal Follistatin inhibits fibrosis and promotes muscle regeneration in mice by influencing Smad2 and AKT signaling.
Hu H, Yin Y, Zhou H, Jiang B, Cai T, Wu S, Guo S
Experimental cell research 2025 Jan 15;444(2):114396
Experimental cell research 2025 Jan 15;444(2):114396
Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc(-)/GSH/GPX4 axis.
Yu FF, Zuo J, Wang M, Yu SY, Luo KT, Sha TT, Li Q, Dong ZC, Zhou GY, Zhang F, Guo X, Ba Y, Wang YJ
Ecotoxicology and environmental safety 2025 Jan 15;290:117569
Ecotoxicology and environmental safety 2025 Jan 15;290:117569
Discovery of a potent anticancer agent against pancreatic ductal adenocarcinoma targeting FAK with DFG-out state and JAK/Aurora kinases.
Zhang RH, Chen T, Xiong QQ, Wang S, Chen GQ, Zhang WL, Yuan HF, Zhao YL, Liu T, Huang Y, Zhou M, Yang CL, Liao SG, Li YJ
European journal of medicinal chemistry 2025 Jan 15;282:117059
European journal of medicinal chemistry 2025 Jan 15;282:117059
Exploring the potential anti-COPD ingredients and mechanisms of the Qingfei decoction based on UHPLC-HRMS, network pharmacology and transcriptomic analysis.
Zhang T, Guo Z, Ma T, Li S, Dai Z, Luo Y, Gao F, Zeng Q, Lu J, Wang J, Liu Y, Xu B, Lei H
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Jan 15;1251:124420
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Jan 15;1251:124420
Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention.
Wang X, Deng X, Xin L, Dong C, Hu G, Zhou HB
Molecules (Basel, Switzerland) 2025 Jan 14;30(2)
Molecules (Basel, Switzerland) 2025 Jan 14;30(2)
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Xu P, Shao R, Zhu P, Fei J, He Y
International journal of molecular sciences 2025 Jan 14;26(2)
International journal of molecular sciences 2025 Jan 14;26(2)
Butyrate attenuates high-fat diet-induced glomerulopathy through GPR43-Sirt3 pathway.
Shi Y, Xing L, Zheng R, Luo X, Yue F, Xiang X, Qiu A, Xie J, Russell R, Zhang D
The British journal of nutrition 2025 Jan 14;133(1):1-10
The British journal of nutrition 2025 Jan 14;133(1):1-10
Mechanism of Buyang Huanwu Decoction mediating Cav1-regulated Wnt pathway to promote neural regeneration in cerebral ischemic mice.
OuYang Y, Yi J, Chen B, Zeng F, Chen X, Yang H, Xu Y, Liu Z, Ning W, Liu B
Journal of ethnopharmacology 2025 Jan 13;339:119121
Journal of ethnopharmacology 2025 Jan 13;339:119121
Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.
Geng J, Zhang X, Guo Y, Wen H, Guo D, Liang Q, Pu S, Wang Y, Liu M, Li Z, Hu W, Yang X, Chang P, Hu L, Li Y
Nature communications 2025 Jan 12;16(1):613
Nature communications 2025 Jan 12;16(1):613
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC.
Dong Y, Liu X, Li J, Lin T, Wang R, Jiang H, Wang Y, Yue D
Functional & integrative genomics 2025 Jan 11;25(1):12
Functional & integrative genomics 2025 Jan 11;25(1):12
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Teng Y, Zhao H, Xue G, Zhang G, Huang Y, Guo W, Zou K, Zou L
Journal of translational medicine 2025 Jan 11;23(1):44
Journal of translational medicine 2025 Jan 11;23(1):44
Developmental exposure to perfluorooctane sulfonate(PFOS) impairs the endometrial receptivity.
Ren R, Zhou X, Jia T, Wang B, Liu A, Gao M, Song J, Wang L, Jing Y, Yu L, Shen H, Zhang X
Scientific reports 2025 Jan 11;15(1):1747
Scientific reports 2025 Jan 11;15(1):1747
Gestational exposure to carbon black nanoparticles triggered fetal growth restriction in mice: The mediation of inactivating autophagy-lysosomal degradation system in placental ferroptosis.
Li J, Gao H, Xu Z, Gao B, Zhang L, Su B, Yang S, Liu J, Liu Y, Wang X, Wang H, Lin Y, Shen H
The Science of the total environment 2025 Jan 10;959:178167
The Science of the total environment 2025 Jan 10;959:178167
Hyperactivity of the IL-33-ILC2s-IL-13-M-MDSCs axis promotes cervical cancer progression.
Wang B, Zhu Y, Zhang Y, Ru Z, Chen L, Zhang M, Wu Y, Ding J, Chen Z
International immunopharmacology 2025 Jan 10;144:113693
International immunopharmacology 2025 Jan 10;144:113693
Lovastatin-mediated pharmacological inhibition of Formin protein DIAPH1 suppresses tumor immune escape and boosts immunotherapy response.
Wan M, Zhou J, Xue N, Mei J, Zhou J, Zong X, Ding J, Li Q, He Z, Zhu Y
International immunopharmacology 2025 Jan 10;144:113637
International immunopharmacology 2025 Jan 10;144:113637
RNA m(6)A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells.
Zhang N, Yang J, Zhao Y, Li W, Zhao B, Li R, He Z, Gu S
Cell death discovery 2025 Jan 10;11(1):4
Cell death discovery 2025 Jan 10;11(1):4
Restrictor slows early transcription elongation to render RNA polymerase II susceptible to termination at non-coding RNA loci.
Mimoso CA, Vlaming H, de Wagenaar NP, Adelman K
bioRxiv : the preprint server for biology 2025 Jan 10;
bioRxiv : the preprint server for biology 2025 Jan 10;
Synergistic effects of combined lead and iprodione exposure on P53 signaling-mediated hepatotoxicity, enterotoxicity and transgenerational toxicity in zebrafish.
Wang R, Deng L, Wang Y, Liu N, Yang M, Qiu J, Chen C
The Science of the total environment 2025 Jan 1;958:178127
The Science of the total environment 2025 Jan 1;958:178127
Tryptophan Metabolites Improve Intestinal Mucosal Barrier via the Aryl Hydrocarbon Receptor-Interleukin-22 Pathway in Murine Dextran Sulfate Sodium-Induced Pouchitis.
Zhang T, Yu Z, Xu Y, Zhao L, Zhu F, Zhou Y, Gu L, Gong J
Diseases of the colon and rectum 2025 Jan 1;68(1):77-90
Diseases of the colon and rectum 2025 Jan 1;68(1):77-90
Puerarin reduces diabetic nephropathy-induced podocyte pyroptosis by modulating the SIRT1/NLRP3/caspase-1 pathway.
Wang L, Xie X, Chen Q, Chen Y, Xu X, Liang T
Molecular and cellular endocrinology 2025 Jan 1;595:112409
Molecular and cellular endocrinology 2025 Jan 1;595:112409
COPS5 regulates osteosarcoma progression by upregulating KHSRP to promote Per2 mRNA decay.
Bu J, Xu X, Luo Y, Liu J, Yao X
Experimental cell research 2025 Jan 1;444(1):114358
Experimental cell research 2025 Jan 1;444(1):114358
Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R.
Shi L, Ying H, Dai Y, Rong Y, Chen J, Zhou F, Wang S, Xu S, Tong X, Zhang S
Human reproduction (Oxford, England) 2025 Jan 1;40(1):119-137
Human reproduction (Oxford, England) 2025 Jan 1;40(1):119-137
Alterations in the transcriptome and microRNAs of adipose-derived mesenchymal stem cells from different sites in rats during aging.
Su Z, Xu T, Sun JY, Sun W, Kong X
American journal of physiology. Cell physiology 2025 Jan 1;328(1):C78-C94
American journal of physiology. Cell physiology 2025 Jan 1;328(1):C78-C94
Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring.
Cheng X, Xue Y, Wang H, Ma Z, Hu N, Zhang C, Gao Y, Fan R, Hu L, Li J, Zhang D, Huang J, Fang S, Xiao R, He Y, Luo T, Zheng L
Ecotoxicology and environmental safety 2025 Jan 1;289:117632
Ecotoxicology and environmental safety 2025 Jan 1;289:117632
Hippocampal SENP3 mediates chronic stress-induced depression-like behaviors by impairing the CREB-BDNF signaling.
Gao Z, Peng J, Zhang Y, Chen Z, Song R, Song Z, Feng Q, Sun M, Zhu H, Lu X, Yang R, Huang C
Neuropharmacology 2025 Jan 1;262:110203
Neuropharmacology 2025 Jan 1;262:110203
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Hu Z, Yang J, Zhang S, Li M, Zuo C, Mao C, Zhang Z, Tang M, Shi C, Xu Y
Neural regeneration research 2025 Jan 1;20(1):253-264
Neural regeneration research 2025 Jan 1;20(1):253-264
Downregulation of LncRNA CCAT1 Enhances Chemosensitivity in Cisplatin-Resistant Gastric Cancer Cells.
Wu Q, Zhu C, Zhao T, Liu T, Da M
Drug development research 2025 Feb;86(1):e70048
Drug development research 2025 Feb;86(1):e70048
High expression of ARPC1B promotes the proliferation and apoptosis of clear cell renal cell carcinoma cells, leading to a poor prognosis.
Wang H, Liu Z, Du Y, Cheng X, Gao S, Liang W, Zhu Q, Jiang Z, Gao Y, Shang P
Molecular and cellular probes 2025 Feb;79:102011
Molecular and cellular probes 2025 Feb;79:102011
Lactamase β reprograms lipid metabolism to inhibit the progression of endometrial cancer through attenuating MDM2-mediated p53 ubiquitination and degradation.
Zhou T, Li X, Zhao F, Zhou J, Sun B
Archives of biochemistry and biophysics 2025 Feb;764:110287
Archives of biochemistry and biophysics 2025 Feb;764:110287
Smooth Muscle Cell-Specific LKB1 Protects Against Sugen 5416/Hypoxia-induced Pulmonary Hypertension through Inhibition of BMP4.
Liu Y, Ma X, Lei L, Wang L, Deng Q, Lu H, Li H, Tian S, Qin X, Zhang W, Sun Y
American journal of respiratory cell and molecular biology 2025 Feb;72(2):169-180
American journal of respiratory cell and molecular biology 2025 Feb;72(2):169-180
NCAPD3-mediated AKT activation regulates prostate cancer progression.
Zhang Y, Xie W, Zong X, Fang Y, Ren J, Jing Z, Wei Y, Lu S, Zhu Q, Liu P
FASEB bioAdvances 2025 Feb;7(2):e1488
FASEB bioAdvances 2025 Feb;7(2):e1488
Proline exacerbates hepatic gluconeogenesis via paraspeckle-dependent mRNA retention.
Zhao Y, Chai X, Peng J, Zhu Y, Dong R, He J, Xia L, Liu S, Chen J, Xu Z, Luo C, Sheng J
Nature metabolism 2025 Feb;7(2):367-382
Nature metabolism 2025 Feb;7(2):367-382
RGS22 maintains the physiological function of ependymal cells to prevent hydrocephalus.
Pang X, Gu L, Han QY, Xing JQ, Zhao M, Huang SY, Yi JX, Pan J, Hong H, Xue W, Zhou XQ, Su ZH, Zhang XR, Sun LM, Jiang SZ, Luo D, Chen L, Wang ZJ, Yu Y, Xia T, Zhang XM, Li AL, Zhou T, Cai H, Li T
Science China. Life sciences 2025 Feb;68(2):441-453
Science China. Life sciences 2025 Feb;68(2):441-453
A near-infrared triggered multi-functional indocyanine green nanocomposite with NO gas release function inducing improved photothermal therapy.
Guo L, Zhou Y, Ding J, Xiong J, Zhu L, Amuti S, Zhang C, Du Z, Zhang X, Dong B, Alifu N
Journal of colloid and interface science 2025 Feb;679(Pt B):307-323
Journal of colloid and interface science 2025 Feb;679(Pt B):307-323
Integrin β4 Regulates Cell Migration of Lung Adenocarcinoma Through FAK Signaling.
Zhang S, Liu C, Liu D, Ning X, Li H, Zhang X, Lu Y, Zhang P, Chen S, Cai Z
Molecular biotechnology 2025 Feb;67(2):496-509
Molecular biotechnology 2025 Feb;67(2):496-509
LGR4 promotes proliferation and homing via activation of the NF‑κB signaling pathway in multiple myeloma.
He N, Yang Q, Li Z, Guo J, Kuang C, Zhu Y, Liu X, Chen X, Shi F, Feng X, An G, Zhang G, Zhou W
International journal of oncology 2025 Feb;66(2)
International journal of oncology 2025 Feb;66(2)
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Li J, Wang Y, Wei S, Xu S, Dai S, Zhang L, Tian Z, Zhao L, Lv H
Molecular carcinogenesis 2025 Feb;64(2):244-259
Molecular carcinogenesis 2025 Feb;64(2):244-259
Antiviral mechanism of Fuzhengjiedu San against porcine reproductive and respiratory syndrome virus.
Song XQ, Zhao XY, Chen WS, Yang L, Liu DY, Chen YP
Virology 2025 Feb;603:110382
Virology 2025 Feb;603:110382
In vivo inhibition of CYP2E1 fails to reduce pulegone-induced liver injury in mice.
Huan L, Zhang Y, Liu W, Lu H, Zhang C, Yin R, Ouyang Z, Wei Y
Xenobiotica; the fate of foreign compounds in biological systems 2025 Feb;55(2):121-130
Xenobiotica; the fate of foreign compounds in biological systems 2025 Feb;55(2):121-130
AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane.
Pan Y, Yin Q, Wang Z, Wu G, Liu K, Li X, Liu J, Zeng J, Lin B, Li W, Zhu M, Li M
Translational oncology 2025 Feb;52:102240
Translational oncology 2025 Feb;52:102240
Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma.
An W, Zhang K, Li G, Zheng S, Cao Y, Liu J
Translational oncology 2025 Feb;52:102234
Translational oncology 2025 Feb;52:102234
Trimethylamine N-oxide induces pyroptosis in HTR8-S/Vneo cells through the ten-eleven translocation 2-cytochrome b-reactive oxygen species pathway.
Liang L, Rao Y, Wang J, Zhao J, He L, Meng J, Wu P, Wang Z
The journal of obstetrics and gynaecology research 2025 Feb;51(2):e16237
The journal of obstetrics and gynaecology research 2025 Feb;51(2):e16237
MARCHF1 promotes breast cancer through accelerating REST ubiquitylation and following TFAM transcription.
Li J, Gao Z
Cell biology international 2025 Feb;49(2):161-176
Cell biology international 2025 Feb;49(2):161-176
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Gan X, Luo X, Chen J, Fang W, Nie M, Lu H, Liu Y, Wang X
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway.
Mo S, Liu T, Zhou H, Huang J, Zhao L, Lu F, Kuang Y
Molecular and cellular biochemistry 2025 Feb;480(2):1013-1026
Molecular and cellular biochemistry 2025 Feb;480(2):1013-1026
Low-dose SAHA enhances CD8(+) T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer.
Dong W, He B, Cao Y, Yang R, Zhang S, Kong Y, Lu D, Zheng X, Hou Y, Zhu M, Wang C, Yu S, Cui D, Wang H, Wang B
Cellular oncology (Dordrecht, Netherlands) 2025 Feb;48(1):249-264
Cellular oncology (Dordrecht, Netherlands) 2025 Feb;48(1):249-264
Hypoxia inducible factor-1α promotes non-small cell lung cancer progression by activating leptin receptor transcription.
Li Y, Chen B, Wu S, Zhong Y, Zhang Y, Wu J
Cancer biomarkers : section A of Disease markers 2025 Feb;42(2):18758592251330479
Cancer biomarkers : section A of Disease markers 2025 Feb;42(2):18758592251330479
The Chinese Herbal Medicine Li Qi Huo Xue Di Wan Ameliorates Ischemia or Hypoxia-Induced Cardiac Injury and Remodeling in the Heart Through a Mechanism Involving Reduction of Necroptosis.
Zhang YY, Tang C, Dou YQ, Luo XJ, Pu J, Peng J
Environmental toxicology 2025 Feb;40(2):328-346
Environmental toxicology 2025 Feb;40(2):328-346
PB2 627V and HA 217 sites synergistically affect the lethality of H9N2 in mice.
Zhao L, Tian M, Hu X, Fan M, Hou C, Ping J
Virologica Sinica 2025 Feb;40(1):35-49
Virologica Sinica 2025 Feb;40(1):35-49
Ginsenoside Rb prevents the metastasis of hepatocarcinoma by blocking the platelet-tumor cell interaction.
Miao L, Yang Y, Cheng M, Chen L, Han C
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1721-1733
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1721-1733
The Purinergic Ligand-Gated Ion Channel 7 Receptor Promotes the Proliferation, Invasion, and Migration of Breast Cancer Cells.
Wang X, Peng X, Cao Y, Zhu X, Du Y, Yu Q, Zhao R
Journal of biochemical and molecular toxicology 2025 Feb;39(2):e70184
Journal of biochemical and molecular toxicology 2025 Feb;39(2):e70184
NUC7738 Induces Apoptosis Through Modulating Stability of P53 in Esophageal Cancer Cells.
Wu LF, Ren CH, Xu JC, Zhang YF, Liu YB, Zhou PH, Zhang YQ
Journal of biochemical and molecular toxicology 2025 Feb;39(2):e70175
Journal of biochemical and molecular toxicology 2025 Feb;39(2):e70175
Has_circ_ASH1L acts as a sponge for miR-1254 to promote the malignant progression of cervical cancer by targeting CD36.
Zhang J, Zhang Y, Li X, Bao Y, Yang J
Cancer gene therapy 2025 Feb;32(2):214-226
Cancer gene therapy 2025 Feb;32(2):214-226
H(2)S Donor SPRC Ameliorates Ischemic Stroke by Upregulating CD24.
Wang C, Li S, Li Q, Xi H, Li J, Zhu Q, Wu P, Zhu YZ, Mao Y
CNS neuroscience & therapeutics 2025 Feb;31(2):e70243
CNS neuroscience & therapeutics 2025 Feb;31(2):e70243
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Jia X, Wang Y, Jiang M, Chen DD, Shang G, Liu B, Xue M, Lang Y, Zhou G, Dong Y, Zhang F, Peng X, Hu Y
The Journal of biological chemistry 2025 Feb;301(2):108126
The Journal of biological chemistry 2025 Feb;301(2):108126
SND1-SMARCA5 interaction strengthened by PIM promotes the proliferation, metastasis, and chemoresistance of esophageal squamous cell carcinoma.
Yan Q, Huang S, Zhou M, Deng X, Han F, Yin H, Xu T, Wang C, Li Y, Long Y, Tang X, Gao Y, Dai T, Hu Z, Han B, Wu J
International journal of biological macromolecules 2025 Feb;291:139152
International journal of biological macromolecules 2025 Feb;291:139152
Oxidative potential determines the oxidative stress and ferroptotic toxicity of airborne particulate matter on pulmonary epithelial cells.
Nie B, Zhang D, Liu X, Lei C, Li Z, Zhang N, Zhang S, Wei Y, Zhang J
Ecotoxicology and environmental safety 2025 Feb;291:117845
Ecotoxicology and environmental safety 2025 Feb;291:117845
Progranulin Protects Against Osteoporosis by Regulating Osteoclast and Osteoblast Balance via TNFR Pathway.
Wang S, Zhang H, Zhu Y, Zhou X, Zhai H, He Q, Zhu X, Zhang Y
Journal of cellular and molecular medicine 2025 Feb;29(3):e70385
Journal of cellular and molecular medicine 2025 Feb;29(3):e70385
Antitumor effects of plasma‑activated solution on a murine melanoma model in vivo and in vitro.
Yang X, Chen C, Zhou S, Ren M, Zhang C, Cheng C, Yang C
Oncology letters 2025 Feb;29(2):75
Oncology letters 2025 Feb;29(2):75
Spinal pituitary adenylate cyclase-activating polypeptide and PAC1 receptor signaling system is involved in the oxaliplatin-induced acute cold allodynia in mice.
Takasaki I, Nagashima R, Ueda T, Ashihara Y, Nakamachi T, Okada T, Toyooka N, Miyata A, Kurihara T
The journal of pain 2025 Feb;27:104751
The journal of pain 2025 Feb;27:104751
Aβ -induced excessive mitochondrial fission drives type H blood vessels injury to aggravate bone loss in APP/PS1 mice with Alzheimer's diseases.
Zhang W, Ding F, Rong X, Ren Q, Hasegawa T, Liu H, Li M
Aging cell 2025 Feb;24(2):e14374
Aging cell 2025 Feb;24(2):e14374
CMAP prediction and experimental validation of Forskolin as a podocyte protective and anti-proteinuric drug for nephrotoxic serum-treated mice.
Huang W, Yu P, Zhao X, Shi J, Jin X, Jin R, Dong S, Xia W, Zhu X, Wang J, Zhang H, Ren L, Shi S
Biochemical pharmacology 2025 Feb;232:116727
Biochemical pharmacology 2025 Feb;232:116727
Hyperlipidemia impairs bone repair and regeneration via miR-193a-3p/STMN1/PI3K/Akt axis.
Shang J, Li Z, Ma A, Zhu T, Ma G, Gui H, Ren H, Sun B, Wang W, Wang X, Liu C, Li C, Wang Z, Lan J
Biochemical pharmacology 2025 Feb;232:116693
Biochemical pharmacology 2025 Feb;232:116693
PTX3 impairs granulosa cell function by promoting the secretion of inflammatory cytokines in M1 macrophages via the JAK pathway.
Chen Y, Luo X, Li Y, Liu L, Liu Z, Tan Y, Chen Y
Steroids 2025 Feb;214:109541
Steroids 2025 Feb;214:109541
Elucidating loss-of-function mechanisms of monoallelic EPAS1 mutations underlying congenital hypoplastic anaemia in a paediatric anaemia cohort.
Zhang J, Sun J, Huai W, Tang J, Chen J, Yao R, Yu T
British journal of haematology 2025 Feb;206(2):585-595
British journal of haematology 2025 Feb;206(2):585-595
Long-term effects of Nε-carboxymethyllysine intake on intestinal barrier permeability: Associations with gut microbiota and bile acids.
Qiang X, Wang X, Liang S, Li S, Lv Y, Zhan J
Food research international (Ottawa, Ont.) 2025 Feb;201:115543
Food research international (Ottawa, Ont.) 2025 Feb;201:115543
VNS facilitates the neurological function recovery after ischemia/reperfusion injury by regulating the A1/A2 polarization of astrocytes through the NMU-NMUR2 pathway.
Jiang X, Yang W, Liu G, Tang H, Zhang R, Zhang L, Li C, Li S
Neurochemistry international 2025 Feb;183:105918
Neurochemistry international 2025 Feb;183:105918
5'tiRNA-33-CysACA-1 promotes septic cardiomyopathy by targeting PGC-1α-mediated mitochondrial biogenesis.
Yuan L, Li J, Yin L, Lin X, Ni D, Deng C, Liang P, Jiang B
The international journal of biochemistry & cell biology 2025 Feb;179:106714
The international journal of biochemistry & cell biology 2025 Feb;179:106714
A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway.
Hou Y, Zhong B, Zhao L, Wang H, Zhu Y, Wang X, Zheng H, Yu J, Liu G, Wang X, Martin-Garcia JM, Chen X
Acta pharmaceutica Sinica. B 2025 Feb;15(2):991-1006
Acta pharmaceutica Sinica. B 2025 Feb;15(2):991-1006
Yiqi Huayu Jiedu formula inhibits JAK2/STAT3-mediated partial EMT in treating chronic atrophic gastritis.
Yu W, Chen S, Guan X, He G, Zhang W, Zhang H, Huang S, Ye Z, Pan H, Zhong Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156356
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156356
Specific Monitoring the DNA Helicase Function via Anchor-Embedded DNA Probe.
Ning K, Tang X, Li Z, Zhong L, Zhou Y, Wang J, Huang W, Zhang H, Ke J, Luan T, Chen SB, Zhai J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2413368
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2413368
Gut Commensal Barnesiella Intestinihominis Ameliorates Hyperglycemia and Liver Metabolic Disorders.
Zhang Y, Xu D, Cai X, Xing X, Shao X, Yin A, Zhao Y, Wang M, Fan YN, Liu B, Yang H, Zhou W, Li P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2411181
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2411181
Cis-Regulation of an m(6)A Eraser by an Insertion Variant Associated with Survival of Patients With Non-Small Cell Lung Carcinoma.
Cheng L, Hu Q, Wang Y, Nie W, Lu H, Zhang B, Zhao G, Ding S, Pan F, Shen Y, Zhong R, Zhang R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407652
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407652
D30 Alleviates β2-Microglobulin-Facilitated Neurotoxic Microglial Responses in Isoflurane/Surgery-Induced Cognitive Dysfunction in Aged Mice.
Chen P, Lin WL, Liu XY, Li SJ, Chen RF, Hu ZH, Lin PT, Lin MH, Shi MY, Wu W, Wang Y, Lin QS, Ye ZC
Laboratory investigation; a journal of technical methods and pathology 2025 Feb;105(2):102190
Laboratory investigation; a journal of technical methods and pathology 2025 Feb;105(2):102190
Exploring the Anti-Colorectal Cancer Mechanism of Norcantharidin Through TRAF5/NF-κB Pathway Regulation and Folate-Targeted Liposomal Delivery.
Zhang F, Chen X, Qiao C, Yang S, Zhai Y, Zhang J, Chai K, Wang H, Zhou J, Guo M, Lu P, Wu J
International journal of molecular sciences 2025 Feb 9;26(4)
International journal of molecular sciences 2025 Feb 9;26(4)
PRMT1-mediated methylation regulates MLL2 stability and gene expression.
An D, Kim J, Moon B, Kim H, Nguyen H, Park S, Lee JE, Kim JA, Kim J
Nucleic acids research 2025 Feb 8;53(4)
Nucleic acids research 2025 Feb 8;53(4)
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
Fan XP, Wang JR, Chen SY, Li XR, Cao JL, Wang HB, Ding LY, Che TJ, Yang L
Scientific reports 2025 Feb 8;15(1):4748
Scientific reports 2025 Feb 8;15(1):4748
STEAP3 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by Regulating Fatty Acid and Lipid Droplet Synthesis.
Yuan C, Guan K, Zhang G
Veterinary sciences 2025 Feb 8;12(2)
Veterinary sciences 2025 Feb 8;12(2)
Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma.
Jian Y, Yang K, Li J, Tang L, Zeng G, Sun X, Yu X, Al-Danakh A, Chen Q, Yang D, Wang S
Cancer cell international 2025 Feb 7;25(1):36
Cancer cell international 2025 Feb 7;25(1):36
Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia.
Xie F, Zhang TJ, Zhang XL, Xu ZJ, Qiao L, Wang Y, Zhao YJ, Qian J, Zhou JD
BMC cancer 2025 Feb 7;25(1):215
BMC cancer 2025 Feb 7;25(1):215
Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury.
Zhang L, Yang S, Cui H, Hang C, Wang X, An L, Shan Z, Liang Z, Shao R, Tang Z
Scientific reports 2025 Feb 7;15(1):4607
Scientific reports 2025 Feb 7;15(1):4607
NRG1-ErbB4 signaling in the cerebrospinal fluid-contacting nucleus regulates thermal pain in mice.
Ding Y, Yan Y, Song W, Li Y, Zhao J, Gui B, Zhang Y, Zhang L
Neuroscience 2025 Feb 6;566:132-141
Neuroscience 2025 Feb 6;566:132-141
GATA3-Driven ceRNA Network in Lung Adenocarcinoma Bone Metastasis Progression and Therapeutic Implications.
Liu Y, Shen S, Wang X, Chen H, Ren W, Wei H, Li K, Li L
Cancers 2025 Feb 6;17(3)
Cancers 2025 Feb 6;17(3)
Elevating VAPB-PTPIP51 integration repairs damaged mitochondria-associated endoplasmic reticulum membranes and inhibits lung fibroblasts activation.
Ban J, Tian H, Wei Y, Ao L, Gu H, Zeng J, Peng X, Ao C, Zhang Y, He X, Zhao H, Li J
International immunopharmacology 2025 Feb 6;147:113982
International immunopharmacology 2025 Feb 6;147:113982
Ferristatin II protects nucleus pulposus against degeneration through inhibiting ferroptosis and activating HIF-1α pathway mediated mitophagy.
Su C, Jing X, Liu X, Shao Y, Zheng Y, Liu X, Cui X
International immunopharmacology 2025 Feb 6;147:113895
International immunopharmacology 2025 Feb 6;147:113895
Blockade of neddylation through targeted inhibition of DCN1 alleviates renal fibrosis.
Huo JL, Fu W, Feng Q, Pan S, Liu D, Liu Z
Clinical science (London, England : 1979) 2025 Feb 6;139(3):229-46
Clinical science (London, England : 1979) 2025 Feb 6;139(3):229-46
Bi-allelic KICS2 mutations impair KICSTOR complex-mediated mTORC1 regulation, causing intellectual disability and epilepsy.
Buchert R, Burkhalter MD, Huridou C, Sofan L, Roser T, Cremer K, Alvi JR, Efthymiou S, Froukh T, Gulieva S, Guliyeva U, Hamdallah M, Holder-Espinasse M, Kaiyrzhanov R, Klingler D, Koko M, Matthies L, Park J, Sturm M, Velic A, Spranger S, Sultan T, Engels H, Lerche H, Houlden H, Pagnamenta AT, Borggraefe I, Weber Y, Bonnen PE, Maroofian R, Riess O, Weber JJ, Philipp M, Haack TB
American journal of human genetics 2025 Feb 6;112(2):374-393
American journal of human genetics 2025 Feb 6;112(2):374-393
Comparative mitochondrial proteomic: PGAM5-mediated necroptosis through excessive mitophagy in sheep livers under molybdenum and cadmium co-exposure.
Xiong Z, Yang F, Dai X, Xing C, Bai H, Liu L, Wang Y, Cao H
Journal of hazardous materials 2025 Feb 5;483:136686
Journal of hazardous materials 2025 Feb 5;483:136686
Tissue accumulation and hepatotoxicity of 8:2 chlorinated polyfluoroalkyl ether sulfonate: A multi-omics analysis deciphering hepatic amino acid metabolic dysregulation in mice.
Tan Z, An Z, Lv J, Xiao F, Li L, Li J, Duan W, Guo M, Zeng X, Liu Y, Li A, Guo H
Journal of hazardous materials 2025 Feb 5;483:136668
Journal of hazardous materials 2025 Feb 5;483:136668
Synthesis of novel deuterated EGFR/ALK dual-target inhibitors and their activity against non-small cell lung cancer.
Nie H, Zhang S, Wang L, Wang M, Qiu J, Jia F, Li X, Tian G, An B
European journal of medicinal chemistry 2025 Feb 5;283:117146
European journal of medicinal chemistry 2025 Feb 5;283:117146
Bispecific Aptamer-Drug Conjugates Selectively Eliminate Malignant Hematologic Cells for Treating Acute Myeloid Leukemia.
Li X, Dai J, Shi Y, Chen J, Zhou F, Qian X, Wang P, Fu X, Tan W
Langmuir : the ACS journal of surfaces and colloids 2025 Feb 4;41(4):2580-2590
Langmuir : the ACS journal of surfaces and colloids 2025 Feb 4;41(4):2580-2590
Integrative bioinformatics and experimental analyses identify U2SURP as a novel lactylation-related prognostic signature in esophageal carcinoma.
Zheng X, Zhang X, Li D, Wang Z, Zhang J, Li J, Li Y
Immunologic research 2025 Feb 3;73(1):45
Immunologic research 2025 Feb 3;73(1):45
Implantable Polymer Scaffolds Loaded with Paclitaxel-Cyclodextrin Complexes for Post-Breast Cancer Tissue Reconstruction.
Balahura Stămat LR, Dinu AI, Lungu A, Herman H, Balta C, Hermenean A, Șerban AI, Dinescu S
Polymers 2025 Feb 3;17(3)
Polymers 2025 Feb 3;17(3)
FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung adenocarcinoma.
Gao X, Huang D, Liu Y, Zhang G, Zheng X, Guan B, Chen A, Wu J, Luo SM, Liu Z, Chen L, Liu X, Jin J, Yin X, Sun Z, Zhang Y, Lu M, Zhang G, Liu W, Liu L
Cell death & disease 2025 Feb 3;16(1):63
Cell death & disease 2025 Feb 3;16(1):63
Liver ALKBH5 regulates glucose and lipid homeostasis independently through GCGR and mTORC1 signaling.
Ding K, Zhang Z, Han Z, Shi L, Li X, Liu Y, Li Z, Zhao C, Cui Y, Zhou L, Xu B, Zhou W, Zhao Y, Wang Z, Huang H, Xie L, Chen XW, Chen Z
Science (New York, N.Y.) 2025 Feb 28;387(6737):eadp4120
Science (New York, N.Y.) 2025 Feb 28;387(6737):eadp4120
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
You B, Zhang J, Yang C, Dun Y, Qi D, Long Y, Cheng J, Lin Y, Zhou N, Zeng T, Dong J, Liu S
Chinese medicine 2025 Feb 28;20(1):27
Chinese medicine 2025 Feb 28;20(1):27
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
Dong M, Ma X, Li F
Stem cell research & therapy 2025 Feb 28;16(1):103
Stem cell research & therapy 2025 Feb 28;16(1):103
The Regulatory Role of CircAGGF1 in Myogenic Differentiation and Skeletal Muscle Development.
Hei W, Gong Y, Cai W, Li R, Chen J, Zhang W, Ji M, Li M, Yang Y, Cai C, Guo X, Li B
Animals : an open access journal from MDPI 2025 Feb 28;15(5)
Animals : an open access journal from MDPI 2025 Feb 28;15(5)
A novel necroptosis-related miRNA signature for predicting the prognosis of esophageal cancer and immune infiltration analysis.
Zhang M, Song S, Wang B, Shang Y, Liu P, Li J
Translational cancer research 2025 Feb 28;14(2):949-965
Translational cancer research 2025 Feb 28;14(2):949-965
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Deubiquitination enzyme USP35 negatively regulates MAVS signaling to inhibit anti-tumor immunity.
Zhang H, Zhu J, He R, Xu L, Chen Y, Yu H, Sun X, Wan S, Yin X, Liu Y, Gao J, Li Y, Li Z, Lu Y, Xu Q
Cell death & disease 2025 Feb 27;16(1):138
Cell death & disease 2025 Feb 27;16(1):138
Identification of ETV4 as a prognostic biomarker and correlates with immune cell infiltration in head and neck squamous cell carcinoma.
Tang Y, Xie W, Hu T, Huang C, Yin W, Wei S, Lai F, Tang L
Scientific reports 2025 Feb 27;15(1):7044
Scientific reports 2025 Feb 27;15(1):7044
LOX(+) iCAFs in HNSCC have the potential to predict prognosis and immunotherapy responses revealed by single cell RNA sequencing analysis.
Liu X, Li H, Wang Y, Zhang Q, Liu Y, Liu T
Scientific reports 2025 Feb 27;15(1):7028
Scientific reports 2025 Feb 27;15(1):7028
The long noncoding RNA LUCAT1 regulates endometrial receptivity via the miR-495-3p/S100P axis.
Shang J, Chen Y, Jiang Q, Li W, Lu M, Zhou J, Lin L, Xing J, Zhang M, Zhao S, Lu J, Shi X, Liu Y, Zhu X
Communications biology 2025 Feb 26;8(1):318
Communications biology 2025 Feb 26;8(1):318
Effects of simulated microgravity on dental pulp stem cell stemness.
Hou H, Qiu Z, Che J, Li Y, Sun J, Zhang W, Ma J, Zhang S, Li M, Niu Y, He L
Journal of molecular histology 2025 Feb 26;56(2):97
Journal of molecular histology 2025 Feb 26;56(2):97
Comparative Analysis of Egg Yolk Phospholipid Unsaturation and Its Impact on Neural Health in Alzheimer Disease Mice.
Sun Y, Wu Y, Fang B, Li J, Liu Y, Gao H, Zhang M
Foods (Basel, Switzerland) 2025 Feb 26;14(5)
Foods (Basel, Switzerland) 2025 Feb 26;14(5)
Bioactive Decellularized Extracellular Matrix Platform Integrating Multifunctional Nanozymes and Cell-Laden Microgels for Acute Liver Failure Treatment.
Chen X, Zhang J, Lin T, Zhou F, Li F, Xue T, Zhong Q, Lee W, Chen G, Wang H, Ju E, Li M, Tao Y
ACS nano 2025 Feb 25;19(7):6890-6910
ACS nano 2025 Feb 25;19(7):6890-6910
Terahertz Wave Desensitizes Ferroptosis by Inhibiting the Binding of Ferric Ions to the Transferrin.
Li X, Li Y, Xu J, Lu X, Ma S, Sun L, Chang C, Min L, Fan C
ACS nano 2025 Feb 25;19(7):6876-6889
ACS nano 2025 Feb 25;19(7):6876-6889
The PAR6B-PRKCI-PAR3 complex influences alveolar regeneration in patients with the emphysema subtype of chronic obstructive pulmonary disease.
Wang D, Liu H, Bai S, Zheng X, Zhao L
Stem cell research & therapy 2025 Feb 25;16(1):97
Stem cell research & therapy 2025 Feb 25;16(1):97
RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer.
Huo L, Huang X, Wang Y, Ouyang Y, Zheng X, Ouyang Y, Cao X, Chen K, Wei D, Wu Y, Zhang R, Lin Y, Kang T, Gao Y
Cell death & disease 2025 Feb 25;16(1):130
Cell death & disease 2025 Feb 25;16(1):130
Tumor vascular endothelial cells promote immune escape by upregulating PD-L1 expression via crosstalk between NF-κB and STAT3 signaling pathways in nasopharyngeal carcinoma.
Wang Y, Chen Y, Liu Y, Zhao J, Wang G, Chen H, Tang Y, Ouyang D, Xie S, You J, Yang X, Li M, Xia J, Xiang T, Weng D
Cell death & disease 2025 Feb 25;16(1):129
Cell death & disease 2025 Feb 25;16(1):129
Efficacy of Naringenin against aging and degeneration of nucleus pulposus cells through IGFBP3 inhibition.
Tang X, Zhong J, Luo H, Zhou F, Wang L, Lin S, Xiong J, Lv H, Zhou Z, Yu H, Cao K
Scientific reports 2025 Feb 25;15(1):6780
Scientific reports 2025 Feb 25;15(1):6780
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Wu Y, Meng L, Zhan S, Li M, Huang J, Chen X, Chen L, Gao X, Chen H, Chen H, Zhong Y, Xu L, Xu Y
Journal of translational medicine 2025 Feb 24;23(1):224
Journal of translational medicine 2025 Feb 24;23(1):224
Isolation and characterization of bovine coronavirus variants with mutations in the hemagglutinin-esterase gene in dairy calves in China.
Zhao L, Wang D, Jiang H, Gu Q, Gao H, Zhang L, Liu W, Li S, Kang X, Guo K
BMC veterinary research 2025 Feb 24;21(1):92
BMC veterinary research 2025 Feb 24;21(1):92
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m(6)A methylation: a novel mechanism early during radiation-induced liver injury.
Song GY, Yu QH, Xing XK, Fan XM, Xu SG, Zhang WB, Wu YY, Zhang N, Chao TZ, Wang F, Ding CS, Guo CY, Ma L, Sun CY, Duan SY, Xu P
Cell death & disease 2025 Feb 24;16(1):127
Cell death & disease 2025 Feb 24;16(1):127
Petroselinic Acid from Apiaceae Family Plants Ameliorates Autoimmune Disorders Through Suppressing Cytosolic-Nucleic-Acid-Mediated Type I Interferon Signaling.
Guo Y, Wang YY, Wang Y, Liu YH, Liu JY, Shen YY, Cao AP, Wang RB, Xie BY, Pan X, Li AL, Zhou T, Wang N, Xia Q, Zhang WN
Biomolecules 2025 Feb 24;15(3)
Biomolecules 2025 Feb 24;15(3)
Trp31 Residue of Trx-1 Is Essential for Maintaining Antioxidant Activity and Cellular Redox Defense Against Oxidative Stress.
He Z, Yan Y, Guo X, Wang T, Liu X, Ding RB, Fu Y, Bao J, Qi X
Antioxidants (Basel, Switzerland) 2025 Feb 24;14(3)
Antioxidants (Basel, Switzerland) 2025 Feb 24;14(3)
Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development.
Yuan F, Yang J, Ma F, Hu Z, Malik V, Zang R, Li D, Shi X, Huang X, Zhou H, Wang J
Nature communications 2025 Feb 23;16(1):1900
Nature communications 2025 Feb 23;16(1):1900
Cancer-secreted exosomal miR-1825 induces angiogenesis to promote colorectal cancer metastasis.
Sun J, Luo J, Liu J, Wu H, Li Y, Xu Y, Liu L, Liu X, Zhang Q
Cancer cell international 2025 Feb 22;25(1):63
Cancer cell international 2025 Feb 22;25(1):63
The Unveiled Novel regulator of Adeno-associated virus production in HEK293 cells.
Yan J, Li Z, Shu Y, Chen H, Wang T, Li X, Zhang Y, Li L, Zhang Y
Gene 2025 Feb 20;938:149122
Gene 2025 Feb 20;938:149122
Angiogenin-catalyzed cleavage within tRNA anticodon-loops identified by cP-RNA-seq.
Shigematsu M, Matsubara R, Gumas J, Kawamura T, Kirino Y
Bioscience, biotechnology, and biochemistry 2025 Feb 20;89(3):398-405
Bioscience, biotechnology, and biochemistry 2025 Feb 20;89(3):398-405
eEF2K regulates pain through translational control of BDNF.
Smith PR, Garcia G, Meyer AR, Ryazanov AG, Ma T, Loerch S, Campbell ZT
Molecular cell 2025 Feb 20;85(4):756-769.e5
Molecular cell 2025 Feb 20;85(4):756-769.e5
O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway.
Yan Z, Li Y, Wang M, Xu K, Liu Y, Wang L, Luo H, Chen Z, Liu X
International immunopharmacology 2025 Feb 20;148:114098
International immunopharmacology 2025 Feb 20;148:114098
Bispecific antibody simultaneously targeting AGR2 and PD1 mediates cytotoxic T-cell-induced antitumor response in AGR2-dependent manner and inhibits AGR2-induced PDL1 upregulation.
Roy D, He Y, Wang Y, Xu P, Jin B, Xiao H, Li D, Zhao B
Scientific reports 2025 Feb 19;15(1):6015
Scientific reports 2025 Feb 19;15(1):6015
Al-Based Metal-Organic Nanoslice-Coupled Phospholipid Layer Enables Highly Enriched Biological External Vesicles.
Wang B, Zhao Y, Zhao M, Han Y, Zhang H, Kong W, Qu F
Analytical chemistry 2025 Feb 18;97(6):3319-3327
Analytical chemistry 2025 Feb 18;97(6):3319-3327
KRAS(G12D)-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC.
Jiang X, Wang T, Zhao B, Sun H, Dong Y, Ma Y, Li Z, Wu Y, Wang K, Guan X, Long B, Qin L, Shi W, Shi L, He Q, Liu W, Li M, Xiao L, Zhou C, Sun H, Yang J, Guan J, Zhou H, Yu Z, Jiao Z
Cell reports. Medicine 2025 Feb 18;6(2):101966
Cell reports. Medicine 2025 Feb 18;6(2):101966
CXCR4-targeted PET imaging in rheumatoid arthritis: a novel approach for monitoring disease activity and therapeutic response.
Han Y, Cao S, Liu J, Ding B, Wang S, Pan J, Ge Y, Cheng K, Wang L, Ge L
EJNMMI research 2025 Feb 18;15(1):10
EJNMMI research 2025 Feb 18;15(1):10
Hydrogen sulfide attenuates sepsis-induced cardiac dysfunction in infant rats by inhibiting the expression of cold-inducible RNA-binding protein.
Li D, Jin S, Teng X, Wang P, He K, Cao L, Du J, Guo Q, Xiao L, Xue H, Tian D, An C, Wu Y
Bioscience reports 2025 Feb 17;45(2)
Bioscience reports 2025 Feb 17;45(2)
Fucoidan ameliorates lipid accumulation, oxidative stress, and NF-κB-mediated inflammation by regulating the PI3K/AKT/Nrf2 signaling pathway in a free fatty acid-induced NAFLD spheroid model.
Chu X, Wang X, Feng K, Bi Y, Xin Y, Liu S
Lipids in health and disease 2025 Feb 17;24(1):55
Lipids in health and disease 2025 Feb 17;24(1):55
Estrogen Promotes Endometrial Cancer Development by Modulating ZNF626, SLK, and RFWD3 Gene Expression and Inducing Immune Inflammatory Changes.
Fan J, Zhang M, Wu H, Ye Z, Wang L
Biomedicines 2025 Feb 17;13(2)
Biomedicines 2025 Feb 17;13(2)
Sulfonated albumin from hepatocytes accelerates liver fibrosis in nonalcoholic fatty liver disease through endoplasmic reticulum stress.
Liu T, Sui M, Tian M, Wu N, Zhao S, Wang Y, Yang Y, Ma S, Jiao D, Wang L, Feng Y, Zhang Y, Qin C, Liu C, Qi J, Zhu Q
Free radical biology & medicine 2025 Feb 16;228:150-162
Free radical biology & medicine 2025 Feb 16;228:150-162
Luteolin alleviates diabetic cardiac injury related to inhibiting SHP2/STAT3 pathway.
Pan J, Chen MY, Jiang CY, Zhang ZY, Yan JL, Meng XF, Han YP, Lou YY, Yang JT, Qian LB
European journal of pharmacology 2025 Feb 15;989:177259
European journal of pharmacology 2025 Feb 15;989:177259
FADS1 inhibition protects retinal pigment epithelium cells from ferroptosis in age related macular degeneration.
Zhang A, Wei TT, Tan X, Tan CY, Zhuang M, Xie TH, Cai J, Yao Y, Zhu L
European journal of pharmacology 2025 Feb 15;989:177227
European journal of pharmacology 2025 Feb 15;989:177227
Sodium Butyrate Alleviates Heat Stress-Induced Oxidative Stress and Skeletal Muscle Homeostasis Disruption by Promoting Autophagy in Mice.
Lu J, Li C, Zhao T, Li F, Yao Z, Dong Y, Gong Z, Yan Y, Luo X, Wang H
Nutrients 2025 Feb 15;17(4)
Nutrients 2025 Feb 15;17(4)
Isoliquiritigenin Ameliorates High-Fat Diet-Induced Obesity in Mice by Activating Brown Adipose Tissue.
Zhao L, Li M, Zhu Q, Fang X, Yang H, Zhao Y
International journal of molecular sciences 2025 Feb 14;26(4)
International journal of molecular sciences 2025 Feb 14;26(4)
Cryoablation-induced modulation of Treg cells and the TGF-β pathway in lung adenocarcinoma: implications for increased antitumor immunity.
Lin S, Liu D, Liang T, Zhuang Y, Wang X, Ma S, Li Q, Hu K
BMC medicine 2025 Feb 14;23(1):89
BMC medicine 2025 Feb 14;23(1):89
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
Li W, Li Y, Xiao L, Xie Z, Peng J, Huang W, Li X, Meng Y
Journal of translational medicine 2025 Feb 14;23(1):181
Journal of translational medicine 2025 Feb 14;23(1):181
Circular RNA APP contributes to Alzheimer's disease pathogenesis by modulating microglial polarization via miR-1906/CLIC1 axis.
Wu DP, Wei YS, Hou LX, Du YX, Yan QQ, Liu LL, Zhao YD, Yan RY, Yu C, Zhong ZG, Huang JL
Alzheimer's research & therapy 2025 Feb 14;17(1):44
Alzheimer's research & therapy 2025 Feb 14;17(1):44
Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers.
Li K, Yu X, Xu Y, Wang H, Liu Z, Wu C, Luo X, Xu J, Fang Y, Ju E, Lv S, Chan HF, Lao YH, He W, Tao Y, Li M
Nature communications 2025 Feb 14;16(1):1629
Nature communications 2025 Feb 14;16(1):1629
Activation of Adenosine Triphosphate-Gated Purinergic 2 Receptor Channels by Transient Receptor Potential Vanilloid Subtype 4 in Cough Hypersensitivity.
Li W, Wang S, Zhang T, Zhu Y, Yu L, Xu X
Biomolecules 2025 Feb 14;15(2)
Biomolecules 2025 Feb 14;15(2)
Bioinformatics analysis and validation of novel biomarkers and competitive endogenous RNA networks involved in pyroptosis in diabetic nephropathy.
Wu S, Yao L, Zhang W, Chen P, Jiang J, Ma Y
Scientific reports 2025 Feb 14;15(1):5530
Scientific reports 2025 Feb 14;15(1):5530
Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as the First Bifunctional PI3Kδ Isoform Selective/Bromodomain and Extra-Terminal Inhibitors.
Ran K, Huang JH, Li Y, Zhang Y, Hu H, Wang Z, Tang DY, Li HY, Xu ZG, Chen ZZ
Journal of medicinal chemistry 2025 Feb 13;68(3):3260-3281
Journal of medicinal chemistry 2025 Feb 13;68(3):3260-3281
Identification of a Potent and Selective CDK9 Degrader as a Targeted Therapeutic Option for the Treatment of Small-Cell Lung Cancer.
Wang Y, Wang M, Ma L, Zhang Y, Jiao Y, Zhang S, Yang Y, Li J, Wei M, Cao S, Zhang K, Liu S, Yang G
Journal of medicinal chemistry 2025 Feb 13;68(3):2528-2550
Journal of medicinal chemistry 2025 Feb 13;68(3):2528-2550
Design, Synthesis and Anti-Inflammatory Evaluation of 3-Substituted 5-Amidobenzoate Derivatives as Novel P2Y(14) Receptor Antagonists via Structure-Guided Molecular Hybridization.
Mao S, Liu W, Wang X, Wang M, Wang S, Yao Y, Duan Y, Song C
Journal of medicinal chemistry 2025 Feb 13;68(3):2483-2503
Journal of medicinal chemistry 2025 Feb 13;68(3):2483-2503
Multi-dimensional bio mass cytometry: simultaneous analysis of cytoplasmic proteins and metabolites on single cells.
Qin S, Zhang X, Zhang Y, Miao D, Wei W, Bai Y
Chemical science 2025 Feb 12;16(7):3187-3197
Chemical science 2025 Feb 12;16(7):3187-3197
Mettl3/Eed/Ythdc1 regulatory axis controls endometrial receptivity and function.
Hu X, Li J, Ding C, Jiang J, Xia W, Lu J, Su H, Zhang M, Li H, Liu JL, Lin Y, Meng Q, Huang B
Communications biology 2025 Feb 11;8(1):215
Communications biology 2025 Feb 11;8(1):215
The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance.
Xu Y, Wang Q, Wang J, Qian C, Wang Y, Lu S, Song L, He Z, Liu W, Wan W
Immunity 2025 Feb 11;58(2):309-325.e6
Immunity 2025 Feb 11;58(2):309-325.e6
Cumulative experience meets modern science: Remarkable effects of TongXieYaoFang formula on facilitating intestinal mucosal healing and secretory function.
Du X, Liu L, Yang L, Zhang Y, Dong K, Li Y, Chen Y, Yang Q, Zhu X, Li Q
Journal of ethnopharmacology 2025 Feb 11;341:119370
Journal of ethnopharmacology 2025 Feb 11;341:119370
Dahuang-Gancao decoction ameliorates testosterone-induced androgenetic alopecia in mice.
Qian H, Ye Z, Hu Y, Chen L, Li L, Qin K, Ye Q, Zuo X
Journal of ethnopharmacology 2025 Feb 11;341:119347
Journal of ethnopharmacology 2025 Feb 11;341:119347
P2Y12 receptor-independent antiplatelet mechanism of cryptotanshinone: Network pharmacology and experimental validation of multi-target signaling pathways.
Xiao Y, Zhang R, Hua C, Wu M, Yuan Y, Zhang L, Guo F, Liu J, Yang Z, Liu G
Journal of ethnopharmacology 2025 Feb 11;341:119321
Journal of ethnopharmacology 2025 Feb 11;341:119321
The bitter flavor of Banxia Xiexin decoction activates TAS2R38 to ameliorate low-grade inflammation in the duodenum of mice with functional dyspepsia.
Ren L, Ruan X, Dong H, Cheng Y, Shon K, Chang C, Gu R, Sun Z
Journal of ethnopharmacology 2025 Feb 11;341:119309
Journal of ethnopharmacology 2025 Feb 11;341:119309
Investigating the mechanism of Tongfeng Qingxiao Formula for improving gouty arthritis based on the neutrophil extracellular trapping network.
Li H, Yuan Q, Sun W, Shao Z, Huang X, Hu L, Zhang X
Journal of ethnopharmacology 2025 Feb 11;341:119304
Journal of ethnopharmacology 2025 Feb 11;341:119304
Naoxintong capsule attenuates heart damage after ischemic stroke via Nuclear factor-κB / Pyrin domain-containing protein 3 / Caspase-1 signaling.
Zhang J, Li Y, Chang M, Lei Y, Xu H, Zhang Y, Xu J, Zhang J, Tang S
Journal of ethnopharmacology 2025 Feb 11;341:119240
Journal of ethnopharmacology 2025 Feb 11;341:119240
Induction of the p21/CDK6 pathway and alteration of the immune microenvironment by the stem cell marker CBX3 in melanoma.
Chen W, Zhou L, Jiang J, Chen J, Geng D, Chen Y, Han X, Xie Q, Guo G, Chen X, Tang S, Zhong X
Stem cell research & therapy 2025 Feb 11;16(1):63
Stem cell research & therapy 2025 Feb 11;16(1):63
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis.
Shi J, Chen L, Wang X, Ma X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 10;74(1):35
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 10;74(1):35
Nano-alkaline ion-excited NETs ablative eye drops promote ocular surface recovery.
Zhang J, Zhang L, Sun Z, Li Z, Zou X, Sun S, Zhu L, Xi K, Liu Z, Deng G
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:864-879
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:864-879
Ferulic acid from Angelica sinensis (Oliv.) Diels ameliorates lipid metabolism in alcoholic liver disease via AMPK/ACC and PI3K/AKT pathways.
Lu J, Wang C
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119118
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119118
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
Tao L, Zhang Q, Liu L, Wang K, Liu X, Li J, Zhao P
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
New idea of Fuke Qianjin capsule in treating sequelae of pelvic inflammatory disease: Anti-inflammatory in the early stage and reparative in the later stage.
Xu C, Yi M, Xiao Z, Xiang F, Wu M, Zhang Z, Zheng Y, Gong Y, Li Y, Su L, Liao Y, Zhang P, Xia B, Liao D, Lin L
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119066
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119066
Regulatory effects of yam (Dioscorea opposita Thunb.) glycoprotein on energy metabolism in C2C12 and 3T3-L1 cells and on crosstalk between these two cells.
Li W, Shi J, Wu X, Qiu H, Liu C
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119013
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119013
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
Zhang L, Zheng G, Zhao W, He C, Huang Z
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
NAT10 drives endometriosis progression through acetylation and stabilization of TGFB1 mRNA.
Liu N, YangOu J, Wei C, Li G, Yu R, Lin Y, Xu H
Molecular and cellular endocrinology 2025 Feb 1;597:112447
Molecular and cellular endocrinology 2025 Feb 1;597:112447
Genetic loss of Uchl1 leads to female infertility by affecting oocyte quality and follicular development.
Luo J, Zhang J, Zhang Y, Li M, Yu L, Song D, Sun Z
Molecular and cellular endocrinology 2025 Feb 1;597:112440
Molecular and cellular endocrinology 2025 Feb 1;597:112440
Silencing of APEX1 triggers ferroptosis in clear cell renal cell carcinoma via APP-mediated activation of p53/xCT signaling.
Huang F, Ling H, Wang J
Experimental cell research 2025 Feb 1;445(1):114409
Experimental cell research 2025 Feb 1;445(1):114409
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway.
Huang K, Fang J, Xiao S, Wang W, Zhang G, Sun W, Shuai L, Bi H
Life sciences 2025 Feb 1;362:123341
Life sciences 2025 Feb 1;362:123341
Strontium-Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment.
Yuan W, Liu J, Zhang Z, Ye C, Zhou X, Yi Y, Wu Y, Li Y, Zhang Q, Xiong X, Xiao H, Liu J, Wang J
International journal of oral science 2025 Feb 1;17(1):6
International journal of oral science 2025 Feb 1;17(1):6
miRNA-novel-216 regulated fatty acid composition and progesterone synthesis in goat granulosa cells by targeting the TPD52.
Jia Y, Xu Q, Wang P, Liu Z, Zhang R, Liu K, Ling Y, Liu Y, Chu M
Reproduction (Cambridge, England) 2025 Feb 1;169(2)
Reproduction (Cambridge, England) 2025 Feb 1;169(2)
Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.
Zhang J, Fu Z, Wen F, Lyu P, Huang S, Cai X, Zhang Z, Zhang Y, Fan C, Man W, Sun X, Huang Y
Journal of neurophysiology 2025 Feb 1;133(2):490-501
Journal of neurophysiology 2025 Feb 1;133(2):490-501
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
Wu S, Liu F, Yao X, Lei Y, Wang W
Tissue & cell 2025 Dec;97:103061
Tissue & cell 2025 Dec;97:103061
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Wang B, Xing B, Huang L, Li X, Bian X, Xi J
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
In vitro-Digested Cervus nippon Velvet Antler Polypeptides Alleviate Alcoholic Liver Disease by Suppressing CYP2E1 Activity and Enhancing AMPK Signaling Pathway.
Hao Z, Wang Y, Yang H, Zhang C, Li Y, Wang Y, Yan Y, Huang X, Ding Y
Journal of food science 2025 Dec;90(12):e70711
Journal of food science 2025 Dec;90(12):e70711
A dual absorption pathway of novel oyster-derived peptide-zinc complex enhances zinc bioavailability and restores mitochondrial function.
Yang X, Wang S, Liu H, Zhang T, Cheng S, Du M
Journal of advanced research 2025 Dec;78:47-62
Journal of advanced research 2025 Dec;78:47-62
Lauryl gallate induces apoptosis via p38-MAPK phosphorylation and autophagy in chemoresistant human lung cancer cells.
Huang YH, Cherng SH, Chiu LY, Hsu KH, Tseng JS, Lee PH, Sheu GT, Yang TY
Archives of biochemistry and biophysics 2025 Dec;774:110633
Archives of biochemistry and biophysics 2025 Dec;774:110633
Targeting MSR1 to Facilitate Efferocytosis: A Novel Strategy for Immune Homeostasis Regulation in Irreversible Pulpitis.
Liu S, Dang L, Guo X, Wu K, Qu X, Xu J, Wu B, Chen Z
International dental journal 2025 Dec;75(6):103968
International dental journal 2025 Dec;75(6):103968
Role of TGF-β3 in Regulating Neural Crest Cell Fate and Craniofacial Development: Insights From Zebrafish Models.
Zhang H, Shen S, Qian Y, Zhang L, Pu J, Zhou X, Yang N, Wang W
International dental journal 2025 Dec;75(6):103874
International dental journal 2025 Dec;75(6):103874
von Willebrand Factor Deficiency Inhibits Endothelial-to-Mesenchymal Transition to Attenuate Pulmonary Fibrosis.
Wang W, Chen S, Xi Z, Si Y, Liu Y, Chen J, Wang B, Zhu D, Gong L
American journal of respiratory cell and molecular biology 2025 Dec;73(6):906-919
American journal of respiratory cell and molecular biology 2025 Dec;73(6):906-919
Krill Oil Reverses White Adipose Tissue Dysfunction by Inhibiting Macrophage M1 Polarization in Mice With Type 2 Diabetes.
Pang X, Song D, Huang X, Zheng Y, Sun L, Meng H, Wu H
Molecular nutrition & food research 2025 Dec;69(24):e70215
Molecular nutrition & food research 2025 Dec;69(24):e70215
Flavonols interrupt internalized bacteria hijacking cellular responses via suppressing oxidative stress induced cellular apoptotic death.
Lv R, Cai Z, Sun Z, Zhang W, Wang J, Bian Y, Li Z, Liu X
International journal of antimicrobial agents 2025 Dec;66(6):107595
International journal of antimicrobial agents 2025 Dec;66(6):107595
Wen-Shen-Tong-Luo-Zhi-Tong Decoction alleviates bone loss in aged mice by suppressing LONP1-mediated macrophage senescence.
Zhou Q, Wang K, Wang C, Sun X, Wang L, Sun J, Pan Y, Li M, Zhao Z, Zhou S, Wang Q, Zhang Y, Ma Y, Guo Y
Pharmaceutical biology 2025 Dec;63(1):524-548
Pharmaceutical biology 2025 Dec;63(1):524-548
Modified Xiao-Qing-Long-decoction prevents inflammation and promotes Nur77 expression in mice with acute respiratory distress syndrome by inhibiting HDAC7 expression.
Zhang Q, Liu Y, Jiang L, Yang D
Pharmaceutical biology 2025 Dec;63(1):110-117
Pharmaceutical biology 2025 Dec;63(1):110-117
Naringenin inhibits ferroptosis to reduce radiation-induced lung injury: insights from network Pharmacology and molecular docking.
Jiang J, Deng X, Xu C, Wu Y, Huang J
Pharmaceutical biology 2025 Dec;63(1):1-10
Pharmaceutical biology 2025 Dec;63(1):1-10
Renal Denervation Improves Myocardial Mitochondrial Dysfunction and Myocardial Fibrosis by Inhibiting the NE/KLF15/renalase Pathway.
Chen Y, Fu R, Huang M, Liu T, Zeng L, Li X
Molecular neurobiology 2025 Dec;62(12):16001-16014
Molecular neurobiology 2025 Dec;62(12):16001-16014
Tumor-derived exosomal miR-199b-5p promotes proliferation and epithelial-mesenchymal transition in non-small cell lung cancer by targeting CCNL1.
Liu B, Rui Y, Li M, Huang L
Translational oncology 2025 Dec;62:102564
Translational oncology 2025 Dec;62:102564
Hic-5 deficiency attenuates MAFLD by inhibiting neutrophils migration via the CXCL1-CXCR2 axis.
Ren B, Li H, Liu S, Huang Z, Bai J, Jiang Z, Xu T, Gu B, Yu W, Sun L, Tan P, Fu W
Journal of gastroenterology 2025 Dec;60(12):1535-1553
Journal of gastroenterology 2025 Dec;60(12):1535-1553
LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study.
Wang J, Li C, Wu G, Xu J
Annals of medicine 2025 Dec;57(1):2564284
Annals of medicine 2025 Dec;57(1):2564284
Multi-omics analysis and validation of autophagy-related diagnostic biomarker in osteoarthritis.
Cai Y, Yu D, Meng J, Qiu Y, Liu J, Yao J
Annals of medicine 2025 Dec;57(1):2548045
Annals of medicine 2025 Dec;57(1):2548045
Experimental study on the role and biomarker potential of CX3CR1 in osteoarthritis.
Huang J, Zheng X, Meng J, Wang H, Chen L, Yao J
Annals of medicine 2025 Dec;57(1):2529577
Annals of medicine 2025 Dec;57(1):2529577
Identification of GBP6 as a potential prognostic biomarker in esophageal carcinoma by integrated bioinformatics analysis and experiment validation.
Fang S, Ding Y, Jia Y, Gao L, Ning Y, Wu G, Fang J, Zhang Y, Wang H, Ke H
Annals of medicine 2025 Dec;57(1):2521451
Annals of medicine 2025 Dec;57(1):2521451
m6A reader IGF2BP2 mediates paclitaxel resistance in esophageal squamous cell carcinoma via FOXM1 mRNA stabilization.
Ren S, Wu J, Zhang L, Guan G, Jiang W
Oncology reports 2025 Dec;54(6)
Oncology reports 2025 Dec;54(6)
Regulating SLC7A11/GSH/GPX4 axis by glucose dyshomeostasis to simultaneously promote disulfidptosis, cuproptosis and ferroptosis.
Zhang M, Zheng H, Jin H, Zhu X, Liu S, Chen Y, Zhang H, Zhang S
Bioactive materials 2025 Dec;54:744-758
Bioactive materials 2025 Dec;54:744-758
The mechanistic action of mogroside V in the alleviation of oxidative aging.
Wang Q, Mao X, Li Y, Mo G, Li D, Cao D, Chen G
Artificial cells, nanomedicine, and biotechnology 2025 Dec;53(1):166-180
Artificial cells, nanomedicine, and biotechnology 2025 Dec;53(1):166-180
PACS2/PKCα/NOX4 pathway damaged the renal vascular endothelial barrier by promoting ROS production in diabetic nephropathy mice.
Zheng X, Zhu Q, Ouyang J, Zhang J, Liu Q, Fan J, Gao P, Long H, Xiang H, Lu H
Molecular and cellular biochemistry 2025 Dec;480(12):6145-6156
Molecular and cellular biochemistry 2025 Dec;480(12):6145-6156
March6 Protects Against Acute Kidney Injury by Suppressing Renal Tubular Epithelial Cell Ferroptosis Through the Destabilization of P53 and ACSL4 Proteins.
Feng J, Kong R, Yang Y, Dong H, Guo Y, Xie L
Inflammation 2025 Dec;48(6):4172-4188
Inflammation 2025 Dec;48(6):4172-4188
MLKL-Mediated Necroptosis Predominantly Contributes to Immune-Associated Myocardial Damage.
Sun J, Wu W, Wang Y, Zhang J, Qiu S, Guan Z, Shi C, Ma J, Xu Y
Inflammation 2025 Dec;48(6):3878-3897
Inflammation 2025 Dec;48(6):3878-3897
SIRT6 Overexpression Enhances Diabetic Foot Ulcer Healing via Nrf2 Pathway Activation.
Wei L, Kang M, Zhang G, Meng Y, Qin H
Inflammation 2025 Dec;48(6):3858-3877
Inflammation 2025 Dec;48(6):3858-3877
L1CAM enhances autophagy via inhibition of p38 phosphorylation in colorectal cancer development and progression.
Hu X, Wu T, Xie Y, Zhou J, Liu C, Shi L, Xie L, Shi H
Genes & genomics 2025 Dec;47(12):1333-1342
Genes & genomics 2025 Dec;47(12):1333-1342
Aucubin ameliorates diabetic kidney disease by restoring hGENCs autophagy through promoting phosphorylation of ATG4B protein.
Wang H, Yang L, Ao D, Yang K, Zou S, Lin Z, Liu Q, Wen K
Renal failure 2025 Dec;47(1):2605756
Renal failure 2025 Dec;47(1):2605756
Homozygous FAT1 frameshift mutation linked to glomerulotubular nephropathy with impaired cell adhesion and Rap1 signaling.
Fei Y, Jin Z, He L, Zhang M, Jiao Q, Liu Q, Lin F, Wang W, Wang N, Cao A, Cheng D
Renal failure 2025 Dec;47(1):2561216
Renal failure 2025 Dec;47(1):2561216
A novel APOL1 membrane-addressing domain mutation (p.T272I) in Chinese twins with FSGS: implications for podocyte injury and ion channel disruption.
Peng T, Chang D, Chen T, Chen S, Wang L, Li G
Renal failure 2025 Dec;47(1):2553384
Renal failure 2025 Dec;47(1):2553384
Safflower injection against obesity-induced mice podocyte injury by improving insulin resistance through increasing renal INSR and eNOS expression.
Han Z, Wang X, Liu J, Wang R, Zhao W, Liao H
Renal failure 2025 Dec;47(1):2482888
Renal failure 2025 Dec;47(1):2482888
Role of microvascular pericyte dysfunction in antibody-mediated rejection following kidney transplantation.
Xu J, Pu J, Chen H, Sun L, Fei S, Han Z, Tao J, Ju X, Wang Z, Tan R, Gu M
Renal failure 2025 Dec;47(1):2458749
Renal failure 2025 Dec;47(1):2458749
Gut microbiota-derived butyrate prevents aortic dissection via GPR41.
Yang HX, Wang BX, Dong XL, Sun J, Miao ZL, Pan LL
Acta pharmacologica Sinica 2025 Dec;46(12):3230-3243
Acta pharmacologica Sinica 2025 Dec;46(12):3230-3243
ARHGEF15 Promotes Endothelial Cell Migration Through the Regulation of STAT3 Signaling.
Shi SS, Shang YX, Gao P, Zhang XY, Sun XY, Wang X, Starodubtseva MN, Liu J
Current medical science 2025 Dec;45(6):1428-1435
Current medical science 2025 Dec;45(6):1428-1435
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Qin X, Gao J, Liu X, Chen J, Song X
Biochemistry and biophysics reports 2025 Dec;44:102262
Biochemistry and biophysics reports 2025 Dec;44:102262
Highly efficient prime editors for mammalian genome editing based on porcine retrovirus reverse transcriptase.
Liu W, Duan W, Peng Z, Liao Y, Wang X, Liu R, Jing Q, Jiang H, Fan Y, Ge L, Huang L, Xing Y
Trends in biotechnology 2025 Dec;43(12):3253-3278
Trends in biotechnology 2025 Dec;43(12):3253-3278
RNA and ChIP-sequencing analysis reveals SOX3 suppresses antiviral innate immunity through the AKT1-PTEN signaling axis.
Yousaf T, Chen J, Naz W, Xu J, Liu Y, Huang J, Yang S, Zhang J, Amin I, Guo M, Tang Y, Sun G
Virologica Sinica 2025 Dec;40(6):921-934
Virologica Sinica 2025 Dec;40(6):921-934
Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m(6)A-YTHDF2-dependent mechanism.
Liu TT, Chen LT, Pei XY, Hu SN, Zhuo FF, Chen ZK, Liu Y, Wang JK, Zhang JC, Cao Q, Li L, Wang J, Wei TT, Han B, Tu PF, Zhao XY, Xue R, Zeng KW
iMeta 2025 Dec;4(6):e70089
iMeta 2025 Dec;4(6):e70089
Chicago Sky Blue 6B modulates MAPK/NF-kB pathway in rat knee osteoarthritis.
Zhang Y, Li W, Bai Y, Lai H, Fang J, Ye L, He D, Chen Z
Naunyn-Schmiedeberg's archives of pharmacology 2025 Dec;398(12):17525-17536
Naunyn-Schmiedeberg's archives of pharmacology 2025 Dec;398(12):17525-17536
Stemness reducible effects of glyasperin A against NCCIT teratocarcinomas.
Nguyen TN, Trieu HP, Nguyen TC, Do TP, Le HNH, Tran LNK, Chu HH, Nguyen TN, Pham VC, Nguyen TKO, Do TT
Naunyn-Schmiedeberg's archives of pharmacology 2025 Dec;398(12):17225-17237
Naunyn-Schmiedeberg's archives of pharmacology 2025 Dec;398(12):17225-17237
miR-28-5p targeted Rap1b attenuates splenic inflammation infiltration in immune thrombocytopenia.
Yu R, Cen L, Wu X, Liu H, Zhai X, Bin Q
Platelets 2025 Dec;36(1):2487756
Platelets 2025 Dec;36(1):2487756
Mulberry-derived carbon dots attenuate kidney fibrosis through direct inhibition of PI3K.
Liu T, Wu Y, Wang C, Zhou T, Yang R, Zhang X, Yan W, Fan Q, Lu Z
Materials today. Bio 2025 Dec;35:102626
Materials today. Bio 2025 Dec;35:102626
A bufalin and CRISPR/Cas9 ribonucleoprotein-loaded calcium lactate nanomedicine for pyroptosis/apoptosis and synergistic cancer immunotherapy.
Liu Y, Hou D, Wang H, Yan Q, Xu Y, Wu Q, Dong D, Shen W, Tao W, Cheng H, Sun D
Materials today. Bio 2025 Dec;35:102527
Materials today. Bio 2025 Dec;35:102527
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Li W, Chen J, Yu L, Ding L, Zhang X, Yan L, Shi M
Materials today. Bio 2025 Dec;35:102423
Materials today. Bio 2025 Dec;35:102423
Muscle homing peptide modified liposomes loaded with EGCG improved skeletal muscle dysfunction by inhibiting inflammation in aging mice.
Huang Z, Xie J, Gao N, Feng H, Wang B, Tian H, Wu C, Liu C
Materials today. Bio 2025 Dec;35:102265
Materials today. Bio 2025 Dec;35:102265
S100A4 regulates ferroptosis to suppress cell proliferation via the SLC7A11-GSH axis but facilitates Brucella infection in RAW264.7 macrophages.
Zhang G, Yin Y, Hu H, Tian M, Ding C, Yu S
International journal of biological macromolecules 2025 Dec;333(Pt 1):148831
International journal of biological macromolecules 2025 Dec;333(Pt 1):148831
Atractylodin inhibits ferroptosis in sepsis‑induced acute gastrointestinal injury via SIRT3/PRDX3.
Hu YX, Chen MQ, Wang JL, Wu T, Zhang HD, Li TT, Gao H, Bai Y
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
Acute carbon monoxide poisoning induces renal inflammation and apoptosis via CCL4 upregulation and activation of the PI3K/Akt pathway in mice.
Ni Y, Jiang X, Wang S, Pu T, Yan T, Yu A, Liu Q
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
Aldehyde Dehydrogenase 6 Family Member A1 Facilitates Ti Implant Osseointegration in Hyperlipidemia.
Wang YN, Yu L, Liu Y, Xu X, Zhang D, Liu S, Ge S
Oral diseases 2025 Dec;31(12):3437-3449
Oral diseases 2025 Dec;31(12):3437-3449
Elevated cellular accumulation of endogenous and exogenous CoQ by altered intracellular trafficking.
Wang Y, Hekimi S
The Journal of biological chemistry 2025 Dec;301(12):110878
The Journal of biological chemistry 2025 Dec;301(12):110878
The receptor tyrosine kinase ErbB2/HER2 governs CDK4 inhibitor sensitivity, timing, and irreversibility of the G1/S transition.
Nagasato-Ichikawa A, Murakami K, Aoki K, Okada M
The Journal of biological chemistry 2025 Dec;301(12):110865
The Journal of biological chemistry 2025 Dec;301(12):110865
Identification and validation of the m6A-binding protein LRPPRC to promote tumorigenesis in multiple myeloma.
Tang J, Li J, Qin S, Xiao Y, Liu J, Chen X, Zhang Y
Hematology (Amsterdam, Netherlands) 2025 Dec;30(1):2523082
Hematology (Amsterdam, Netherlands) 2025 Dec;30(1):2523082
Evaluation of the inhibitory effects of emodin on Neospora caninum invasion and proliferation in vitro.
Liu F, Li J, Li X, Zhang X, Yan L, Gao L, Liu Z, Gong P, Zhang N, Zhang X, Wang X
International journal for parasitology. Drugs and drug resistance 2025 Dec;29:100624
International journal for parasitology. Drugs and drug resistance 2025 Dec;29:100624
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion.
Liu H, Wang H, Gao W, Yuan Y, Tang T, Sang M, Liu F, Geng C
Cancer biology & therapy 2025 Dec;26(1):2479926
Cancer biology & therapy 2025 Dec;26(1):2479926
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
Zhou Z, Miao X, Shen Y, Wang P, Shi R, Fan H, Yang Y, Guo M, Wu J
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
Sappanone A, a potential natural inhibitor of PI3K, alleviates metabolic dysfunction-associated steatohepatitis in experimental models.
Qiao X, Li Q, Fan R, Cheng Y, Zeng Q, Xue H, Zhang X, Zhang Y, Liu Y
Biochemical pharmacology 2025 Dec;242(Pt 3):117305
Biochemical pharmacology 2025 Dec;242(Pt 3):117305
Targeting PBK in the fibroblast-to-myofibroblast transition: A novel therapeutic strategy for IPF.
Dong RH, Li X, Yue HH, Zhang FQ, He JH, Dou XR, Li H, Li YH, Li T, Zhang HL
Biochemical pharmacology 2025 Dec;242(Pt 2):117283
Biochemical pharmacology 2025 Dec;242(Pt 2):117283
Progranulin deficiency exacerbates postoperative cognitive dysfunction via RhoA-mediated axodendritic impairment in aged mice.
Lu Y, Tian X, Yang C, Wang D, Yan Y, Wang G, Lei X
Brain research bulletin 2025 Dec;233:111649
Brain research bulletin 2025 Dec;233:111649
RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia.
Shamloo S, Schloßhauer JL, Tiwari S, Denise Fischer K, Almolla O, Ghebrechristos Y, Kratzenberg L, Bejoy AM, Aifantis I, Boccalatte F, Wang E, Imig J
RNA biology 2025 Dec;22(1):1-23
RNA biology 2025 Dec;22(1):1-23
KDM4A-induced tumor senescence enhances the efficacy of immunotherapy by inhibiting AGT-PHB1 axis-mediated mitophagy in colorectal cancer.
Cai T, Liang Z, Chen Z, Li Y, Xiao W, Liang W, Xie H, Liu H, Zeng Z, Yang X, Luo S, Zheng X, Zhong K, Huang L, Xiong L, Kang L
Autophagy 2025 Dec;21(12):2982-3003
Autophagy 2025 Dec;21(12):2982-3003
Nanovaccine loaded with seno-antigen target senescent cells to improve metabolic disorders of adipose tissue and cardiac dysfunction.
Zhang K, Yin Q, Ma Y, Cao M, Li L, Jin X, Leng J
Human vaccines & immunotherapeutics 2025 Dec;21(1):2479229
Human vaccines & immunotherapeutics 2025 Dec;21(1):2479229
Low Expression of Selenoprotein S Promotes Osteogenic Differentiation in Bone Marrow Mesenchymal Stromal Cells.
Wu H, Shi JY, Zhao YS, Shi YW, Zhong LQ, Feng HN, Liu Y, Chen JH, Chen X
Biological trace element research 2025 Dec;203(12):6518-6527
Biological trace element research 2025 Dec;203(12):6518-6527
Involvement of impaired phosphate production and aberrant extracellular ATP signaling in the pathogenesis of hypophosphatasia: Analysis of ALPL-Knockout human iPS cell models.
Yamazaki M, Ueta A, Nakanishi T, Tachikawa K, Kawai M, Ozono K, Michigami T
Bone 2025 Dec;201:117629
Bone 2025 Dec;201:117629
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase-7 in chronic kidney disease.
Liao CT, Lin YC, Huang HJ, Liu WC, Kan WC, Chiu HW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Dec;193:118748
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Dec;193:118748
Shenmai injection attenuates sepsis-associated acute lung injury by remodeling gut microbiota and restoring steroid hormone biosynthesis.
Guo M, Zhao H, Song N, Huang P, Li M, Han L, Zeng KW, Lu Z
Fitoterapia 2025 Dec;187:106935
Fitoterapia 2025 Dec;187:106935
GCN2 regulates paclitaxel-induced neuropathic pain.
Mikesell AR, Meyer AR, García G, Frietze LR, Stucky CL, Pan T, Campbell ZT
British journal of pharmacology 2025 Dec;182(23):5913-5930
British journal of pharmacology 2025 Dec;182(23):5913-5930
Exposure to EP-1 during lactation on maternal behavior, offspring early development, quinestrol transfer and relative receptors in maternal and offspring of Kunming mice.
Yu P, Wu C, Cheng M, Zhang J, Ji X, Lu Y
Psychoneuroendocrinology 2025 Dec;182:107638
Psychoneuroendocrinology 2025 Dec;182:107638
Analysis of the Protective Mechanism of PGC-1α/NRF1/2/TFAM Pathway in Cortical Neuron Injury Induced by Oxidative Stress.
Li J, Zhang W, Hu W, Gao W, Wang J, Li J, Wang Y, Wang W, Gao H, Yi B
Bulletin of experimental biology and medicine 2025 Dec;180(2):259-266
Bulletin of experimental biology and medicine 2025 Dec;180(2):259-266
Hsa_circ_0007349 upregulates glutamate-ammonia ligase to modulate gingival fibroblast wound healing.
Ren L, He L, Zhang R, Li X, Xiao S, Guo S, Liu C, Ding Y
Archives of oral biology 2025 Dec;180:106419
Archives of oral biology 2025 Dec;180:106419
Gut microbes-spinal connection is required for itch sensation.
Jin T, Li SY, Zheng HL, Liu XD, Huang Y, Ma G, Zhao YX, Zhao XT, Yang L, Wang QH, Wang HJ, Gu C, Pan Z, Lin F
Gut microbes 2025 Dec;17(1):2495859
Gut microbes 2025 Dec;17(1):2495859
Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate.
Hu JJ, Deng F, Sun QS, Xiong QM, Min Y, Feng SY, Lin ZB, Chen PH, Hu Z, Wu L, Chen XF, Xie S, Liu WF, Li C, Liu KX
Gut microbes 2025 Dec;17(1):2486515
Gut microbes 2025 Dec;17(1):2486515
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches.
Gong X, Guo T, Li C, Li Z, Li X, Yang L, Li N, Zhan X
The EPMA journal 2025 Dec;16(4):831-856
The EPMA journal 2025 Dec;16(4):831-856
Porcine reproductive and respiratory syndrome virus activates the pentose phosphate pathway via the ROS/HIF-1α/G6PD axis to promote viral replication.
Ma YX, Yang JM, Mei HT, Zeng L, Yang GY, Wang J, Ming SL, Chu BB
Virulence 2025 Dec;16(1):2585639
Virulence 2025 Dec;16(1):2585639
Identification of compounds targeting porcine reproductive and respiratory syndrome virus nsp3 and evaluation of their antiviral efficacy.
He Z, Nie Z, Liao J, Liu M, Li F, Chen B, Guo C
Virulence 2025 Dec;16(1):2530176
Virulence 2025 Dec;16(1):2530176
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and in vivo.
Li LY, Zhou CX, Han B, Elsheikha HM, Qiu HJ, An XD, Zeng T, Liu DA, Yang Q, Zhu XQ, Zhou HY
Virulence 2025 Dec;16(1):2530164
Virulence 2025 Dec;16(1):2530164
The inhibitory and anti-inflammatory effects of TMP269 on peste des petits ruminants virus replication.
Li M, Wang Y, Ke Q, Qu M, Meng X, Sun Y
Virulence 2025 Dec;16(1):2495838
Virulence 2025 Dec;16(1):2495838
Antibody-dependent enhancement of ORFV uptake into host cells.
Tang X, Zhang C, Geng Q, Chen D, Ma W
Virulence 2025 Dec;16(1):2466503
Virulence 2025 Dec;16(1):2466503
Injectable hydrogel-mediated co-delivery of oncolytic adenovirus and melphalan for retinoblastoma control and vision preservation.
Wang G, Wu K, Zhang Z, Chen Y, Li Y, Jiang X, Liang L, Yang Y, Fan H, Sun J, Tong A, Lu F
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6638-6656
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6638-6656
The cytoskeletal protein smoothelin maintains homologous recombination repair by stabilizing RAD51 in an HUWE1-dependent manner in colorectal cancer.
Xu W, Shen M, Ma J, Peng C, Wu S, Yang X, Wu J, Yan Y, Lin N, Gao J, Zhang B
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6444-6460
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6444-6460
Platycodin D inhibits non-small cell lung cancer bone metastasis by inducing ferroptosis through miR-877-3P/PNMA5 regulatory axis.
Xie Z, Zhou Z, Wang S, Wang Y, Cheng K, Lin J, Lu W, Yang H, Lu T, Zheng S, Guo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157534
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157534
Hydroxytyrosol improved insulin resistance in male offspring born to high-fat diet dams by remodeling gut microbiota.
Yi D, Li T, Xiao Y, Li X, Shao B, Wu Z, Hao Q, Zhang F, Zhang X, Yang G, Zhang C, Deng H, Sun X, Wang N
The Journal of nutritional biochemistry 2025 Dec;146:110041
The Journal of nutritional biochemistry 2025 Dec;146:110041
Context-Specific Metabolic Alterations in HPRT1 Knockout Cells Within a 3D Culture System.
Tabata S, Fujimoto I, Soga T, Makinoshima H
Cancer medicine 2025 Dec;14(23):e71452
Cancer medicine 2025 Dec;14(23):e71452
METTL14 Regulates the Expression of Genes Related to Interferon, Interleukin and MHC Class I in Nasopharyngeal Carcinoma Cells.
Zhou Z, Wang J, Shen L, Han L, Li Q, Wu A, Li J, Liang Z, Zhu L, He D, Zhou Y, Huang S, Zhao Z, Cong J, Peng Z, Zhao P, Ye S, Bai B, Hong X, Dai G, Lei Y, Zhao W, Jia J, Lin X, Xiao D, Zhang Y, Lin T
Cancer medicine 2025 Dec;14(23):e71371
Cancer medicine 2025 Dec;14(23):e71371
CircMYO9A inhibits influenza A virus replication by dampening haemagglutinin cleavage via increasing SERPINE1/PAI-1 expression.
Zheng Y, Zhang X, Liu Z, Fan M, Deng L, Ping J
Emerging microbes & infections 2025 Dec;14(1):2502007
Emerging microbes & infections 2025 Dec;14(1):2502007
Glutamate promotes CCL2 expression to recruit tumor-associated macrophages by restraining EZH2-mediated histone methylation in hepatocellular carcinoma.
Chen J, Sun HW, Wang RZ, Zhang YF, Li WJ, Wang YK, Wang H, Jia MM, Xu QX, Zhuang H, Xue N
Oncoimmunology 2025 Dec;14(1):2497172
Oncoimmunology 2025 Dec;14(1):2497172
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Yuan Y, Song S, Xiao Y, Feng R, Li M, Zhang H, Luo L, Wang K, Wang P, Wei L, Zhang Y, Zhang B, Jiang S, Shen K, Guan H, Hu D
Cellular signalling 2025 Dec;136:112172
Cellular signalling 2025 Dec;136:112172
HOXA13 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating SLC7A11 and SLC3A2.
Ma Y, Liu R, Qi P, Wei S, Ren Z, Zhang A, Fan B
Cellular signalling 2025 Dec;136:112168
Cellular signalling 2025 Dec;136:112168
Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ.
Nie C, Liang H, Zhou J, Liu H, Shang R, Yang H, Jiang W, Qi H, Wang J, Gao A
Cellular signalling 2025 Dec;136:112117
Cellular signalling 2025 Dec;136:112117
The RNA-binding protein Quaking modulates cell proliferation through the SFRP1 mediated Wnt signaling pathway in NIH3T3 fibroblasts.
Ma B, Gao D, Han G, Zhang H, Yang W, Tao Y, Liu W, Tang K, Wang A, Jin Y, Chen H
Cellular signalling 2025 Dec;136:112102
Cellular signalling 2025 Dec;136:112102
N2 neutrophils induce cell stemness reprogramming to promote gastric cancer progression via exosomal miRNAs.
Tang H, Zhong Y, Wang J, Meng S, Yu D, Fan B, Dong X, Wang M, Fu M, Qian Y, Zhang X, Ji R, Zhang X, Fang X, Zhang J
Cellular signalling 2025 Dec;136:112085
Cellular signalling 2025 Dec;136:112085
C20orf27 regulates colorectal cancer growth and metastasis based on different lipid levels.
Xu P, Guan H, Du G, Xu Z, Xiong D, Xiao W, Liu X, Sun L
Cellular signalling 2025 Dec;136:112082
Cellular signalling 2025 Dec;136:112082
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
Dan Z, Liu W, Zhang H, Shi X, Zhu R, Yang M, Wang Y, Zhu H
Cellular signalling 2025 Dec;136:112080
Cellular signalling 2025 Dec;136:112080
Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR-NFκB Pathway.
Chen J, Liu N, Tao Q, Wu J, Huang J, Lu C, Li Q, Shen L, Chen X, Peng C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e06139
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e06139
Steroid Receptor Coactivator-1 Drives Tumor-Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion.
Cheng K, Liu L, Gong M, Ji Y, Bai C, Guo X, Chen H, Pan J, Zhang Y, Yuan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e16575
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e16575
A machine learning-based glycolysis and fatty acid metabolism-related prognostic signature is constructed and identified ACSL5 as a novel marker inhibiting the proliferation of breast cancer.
Liang MZ, Huang XF, Zhu JC, Bao JX, Chen CL, Wang XW, Lou YW, Pan YT, Dai YW
Computational biology and chemistry 2025 Dec;119:108507
Computational biology and chemistry 2025 Dec;119:108507
Melatonin improves synaptic morphological plasticity of adolescent male rats after perinatal BDE-209 exposure via SIRT1-mediated LIMK1 and CREB signaling.
Gao J, Shen J, Gao L, Yan D, Wang Y, Meng J, Chen D, Li H, Wu J
Neurotoxicology 2025 Dec;111:103331
Neurotoxicology 2025 Dec;111:103331
Pachymic Acid Suppresses Endometrial Cancer Cell Migration by Inhibiting the NR3C1/TGF-β/Smad Signaling Pathway.
Wang Y, Ma L
Chemical biology & drug design 2025 Dec;106(6):e70226
Chemical biology & drug design 2025 Dec;106(6):e70226
Myosins 1e/f at the podosome base regulate podosome dynamics and promote macrophage migration.
Cervero P, Barger SR, Verdys P, Herzog R, Paul T, Poincloux R, Linder S, Krendel M
European journal of cell biology 2025 Dec;104(4):151514
European journal of cell biology 2025 Dec;104(4):151514
Bioinspired pH-sensitive liposomes for quercetin delivery to synergize with 5- FU in gastric cancer therapy.
Lan Q, Wang M, Zhu Y, Zhang X, Ye R, Wu Z, Lan H, Luo S, Xu Y
International journal of pharmaceutics: X 2025 Dec;10:100437
International journal of pharmaceutics: X 2025 Dec;10:100437
S-palmitoylation-related genes in Crohn's disease: Bioinformatic identification and validation.
Zhou Y, Zhao Y
Biomolecules & biomedicine 2025 Dec 9;26(6):973-985
Biomolecules & biomedicine 2025 Dec 9;26(6):973-985
Identification of potential biomarkers associated with mitochondrial oxidative stress in idiopathic pulmonary arterial hypertension via bioinformatic and experimental analysis.
Zhu Y, Wang X, Yan X, Sun Y, Wang Q, Zhai C
Scientific reports 2025 Dec 9;16(1):1647
Scientific reports 2025 Dec 9;16(1):1647
NMDA receptors coordinate brain vascular development via neuron-to-endothelial tip cell crosstalk in zebrafish.
Liu TT, Li HY, Gu SY, Sun L, Zhang RW, Zu JL, Zhang Y, Yu SG, Zheng XD, Yin JA, Chen Q, He J, Xu B, Du JL
Nature communications 2025 Dec 9;16(1):10856
Nature communications 2025 Dec 9;16(1):10856
The Cx43-Mediated Autophagy Mechanism Influences Triple-Negative Breast Cancer Through the Regulation of Rab31.
Yang J, Wu D, Yang T, Lin ZJ, Jiang PY, Wang TR, Lu ZJ, Wang L, Ming J
Cancers 2025 Dec 8;17(24)
Cancers 2025 Dec 8;17(24)
CXCL10/CXCR3 axis facilitates the M2 polarization of macrophages in colorectal cancer via activating RAF.
Sun X, Chu W, Wei Y, Du D, Li Y
Discover oncology 2025 Dec 8;17(1):70
Discover oncology 2025 Dec 8;17(1):70
Monitoring rapid degradation of NANOG reveals UTP15 maintains pluripotency by regulating nascent transcripts.
Deng M, He D, Wang X, Yuan Y, Wang L, Hou Y, Zhu Q, Zhou C, Mai Z, Zhang Y, Nie Z, Song Y, Wu Q, Pan L, Dong B, Xiong Z, Li D, Liu D, Xu J, Qin D, Zheng H, Zhao Y, Tang P, Wang J, Print C, Jauch R, Zhang W, Wu G, Bao X
Nature communications 2025 Dec 8;17(1):486
Nature communications 2025 Dec 8;17(1):486
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
Deng H, Zhu S, Song X, Guo Y, Ding X
Scientific reports 2025 Dec 8;15(1):43339
Scientific reports 2025 Dec 8;15(1):43339
Screening and identification of differentially expressed miRNA and mRNA for intervertebral disc degeneration on bioinformatics.
Yan J, Gao Y, Chen R, Miao S, Gong Y, Zhu Y, Zhou Q
European journal of medical research 2025 Dec 7;31(1):1
European journal of medical research 2025 Dec 7;31(1):1
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
Zhang Q, Huang S, Liu X, Zhang M, Sun J, Liu M, Nie H, Lei L
Stem cell research & therapy 2025 Dec 7;17(1):27
Stem cell research & therapy 2025 Dec 7;17(1):27
The SREBF2-ACOT7 axis promotes tumor progression and predicts prognosis in diffuse large b-cell lymphoma.
Wang H, Yao X, Wu S, Heng J, Cheng Y, Li L
Scientific reports 2025 Dec 7;15(1):43505
Scientific reports 2025 Dec 7;15(1):43505
Cross-Talk Between Hedgehog and PDGFRα Pathways in mMSCs Modulates Alveolar Bone Regeneration.
Wu L, Liu Z, Yu C, Cao Y, Song K, Mao J
Oral diseases 2025 Dec 7;
Oral diseases 2025 Dec 7;
Autophagy-dependent secretion of ENO1 mediates chemoresistance of glioblastoma and tumor microenvironment remodeling.
Xie Q, Chen L, Huang Y, Yu Z, Zhu R, Li J, Zhao J, Song Y, Li H, Lu Y
Cell death & disease 2025 Dec 6;17(1):79
Cell death & disease 2025 Dec 6;17(1):79
TRIP13 alters mitochondrial function and promotes bortezomib resistance in multiple myeloma.
Chen Y, Liu Y, Wang Y, Qi D, Peng C, Huang S, Guo J, Xu Z, Gu Y
Scientific reports 2025 Dec 6;16(1):1426
Scientific reports 2025 Dec 6;16(1):1426
In silico design, synthesis and biological evaluation of 2-benzyl-5-(2-methoxybenzyl)-1,3,4-oxadiazole derivates as allosteric deoxyhypusine synthase (DHPS) inhibitors for melanoma treatment.
Liu KL, Dong G, Li LT, Liu YZ, Meng QF, Yan YG, Li XY
European journal of medicinal chemistry 2025 Dec 5;299:118061
European journal of medicinal chemistry 2025 Dec 5;299:118061
Lack of intestinal Mucin-1 impairs intestinal epithelial barrier and promotes metabolic dysfunction-associated steatotic liver disease in male mice.
Li Z, Gu R, Liu D, Zhang Y, Qin Y, Li X, Qiao Y, Li Z, Guo J, Wang J, Meng H, Peng L
Nature communications 2025 Dec 5;17(1):321
Nature communications 2025 Dec 5;17(1):321
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
Gao Z, Xiong Z, Tao Y, Wang Q, Guo K, Xu K, Huang H
Chinese medical journal 2025 Dec 5;138(23):3184-3194
Chinese medical journal 2025 Dec 5;138(23):3184-3194
KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis.
He XY, Liu CY, Ding XY, Lin Q, Leng JF, Xiao CM, Zang X, Wang MY, Yin Y, Kong LY, Xia YZ
Nature communications 2025 Dec 4;17(1):191
Nature communications 2025 Dec 4;17(1):191
Human peripheral osteoclast-precursor-development patterns reveal the significance of RPS17-dependent ribosome synthesis to Ankylosing Spondylitis lesions.
Ke D, Dai H, Han J, Su Y, Zhu H, Zhang R, Gao T, Yang L, Yu Y, Bai X, Zhang C, Xu J
Bone research 2025 Dec 4;13(1):100
Bone research 2025 Dec 4;13(1):100
CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis.
Li D, Ou Q, Gao F, Wang X, Zhu L, Zhou Y, Xu JY, Jin C, Wang J, Zhang J, Li J, Bi Y, Lu L, Xu GT, Tian H
Cell death & disease 2025 Dec 31;17(1):156
Cell death & disease 2025 Dec 31;17(1):156
SLC25A3 promotes hepatocellular carcinoma progression by inducing mitochondrial dysfunction and chromatin remodeling.
Deng S, Fu J
Translational cancer research 2025 Dec 31;14(12):8301-8312
Translational cancer research 2025 Dec 31;14(12):8301-8312
Echinacoside as a Novel Ferroptosis Inducer in Hepatocellular Carcinoma: Mechanistic Insights from TP53/SLC7A11/GPX4 Pathway Modulation.
Wang P, Lin J, Su D
International journal of molecular sciences 2025 Dec 30;27(1)
International journal of molecular sciences 2025 Dec 30;27(1)
VAMP5 promotes glioma progression through bioinformatics analysis clinical correlation and functional validation.
Ji Y, Dai X, Zeng H, Liu Z, Cai Z, Li B
Discover oncology 2025 Dec 30;17(1):190
Discover oncology 2025 Dec 30;17(1):190
E4BP4-Driven Circadian SLC6A1 Expression Governs Tiagabine Chronoefficacy in Temporal Lobe Epilepsy.
Yang Y, Li X, Gong S, Sui L, Liu J, Yu F, Zhang T
Molecular neurobiology 2025 Dec 3;63(1):242
Molecular neurobiology 2025 Dec 3;63(1):242
Identification and functional characterization of genes associated with lipopolysaccharide in lung adenocarcinoma.
Zhou S, Gao M, Dong S, Wang M, Xiao H, Shu Y, Wang X
BMC cancer 2025 Dec 3;26(1):54
BMC cancer 2025 Dec 3;26(1):54
IL-1β-stimulated bone mesenchymal stem cell-derived exosomes promote cutaneous wound healing by inhibiting SIRT6/NLRP3 pathway.
Li R, Fan X, He Z, Shen H, Wu H, Chen J, Peng L, Liang B, Feng C, Zhu H
International immunopharmacology 2025 Dec 3;166:115566
International immunopharmacology 2025 Dec 3;166:115566
A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment.
Anderson AP, Kim S, Melton AJ, Ding X, Zhang W, Saltzman AB, Malovannaya A, Rasband MN, Gao Y
Nature communications 2025 Dec 3;16(1):10850
Nature communications 2025 Dec 3;16(1):10850
Targeting TDP1 phosphorylation by the natural product imperatorin promotes DNA repair and cardiac regeneration.
Fu W, Hou L, Yang X, Wang J, Jin J, Tong Q
Communications biology 2025 Dec 29;9(1):151
Communications biology 2025 Dec 29;9(1):151
The Therapeutic Effect and Mechanism of Lactobacillus gardneri on Nonalcoholic Fatty Liver Disease.
Zhu K, Xiang J, Lu F, Wang J, Zhang Y, Feng H, Xiang X
Journal of microbiology and biotechnology 2025 Dec 29;35:e2501051
Journal of microbiology and biotechnology 2025 Dec 29;35:e2501051
1-Deoxynojirimycin Combined with Theaflavins Targets PTGS2/MMP9 to Exert a Synergistic Hypoglycemic Effect.
Wang Y, Qu C, Di Q, Zhang J, Na L
Nutrients 2025 Dec 27;18(1)
Nutrients 2025 Dec 27;18(1)
Integrated serum metabolomics reveal molecular mechanism of Xietu Hemu prescription on metabolic dysfunction-associated steatotic liver disease-related obesity.
Cheng Z, Lu YF, He YX, Wei W, Xie YX, Lv TS, Wei Y, Lou Y, Yu JY, Zhou XQ
World journal of hepatology 2025 Dec 27;17(12):113660
World journal of hepatology 2025 Dec 27;17(12):113660
Sestrin2 Knockdown Impairs Proliferation, Migration, Invasion, and Apoptosis in OSCC Cells via PI3K/AKT/mTOR and MAPK Pathways.
Yang W, Wang W, Zhang Z, Zhao Z, Li K, Liu Z, Xu L, Shi M, Li Y, Wang H
Current issues in molecular biology 2025 Dec 26;48(1)
Current issues in molecular biology 2025 Dec 26;48(1)
Obacunone alleviated the development of polycystic ovary syndrome via inhibiting STAT3 phosphorylation.
Guan L, Wu H, Li Y, Yu Y, Xiang S, Lian F
Journal of ovarian research 2025 Dec 26;19(1):29
Journal of ovarian research 2025 Dec 26;19(1):29
Hypoxic preconditioned mesenchymal stem cell-derived exosomes alleviate oxidative stress-induced cardiomyocyte apoptosis through miR-486-5p.
Zeng ZF, Rao J, Xia XB, Chen XY, He HX, Liu B, Chen Q, Liu YD, Wang GJ, Cheng PC, Wang JN, Wang P, Yu Y, Wang ZN
World journal of stem cells 2025 Dec 26;17(12):112207
World journal of stem cells 2025 Dec 26;17(12):112207
IGF2BP3-STAT3-METTL3 axis promotes malignant progression in hepatocellular carcinoma (HCC).
Xu Y, Cao Y, Yang J, Yu X, Yang L, Xie Y, Zhao J, Zhang Y
Human genomics 2025 Dec 25;20(1):21
Human genomics 2025 Dec 25;20(1):21
Rna analysis of the regulation of expression and alternative splicing in polycystic ovarian syndrome.
Zhang Q, Zhu S, Jiang B
RNA biology 2025 Dec 24;23(1):1-12
RNA biology 2025 Dec 24;23(1):1-12
GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma.
Liu X, Fang S, Ren X, Hong Y, Guo J, Liu X, Gao L, Nie H, Ning Y, Zhang M, Xu F, Liu L, Fang J, Pang Y, Zhao Q, Wang F, Wang H
Nature communications 2025 Dec 24;17(1):964
Nature communications 2025 Dec 24;17(1):964
The crosstalk between ubiquitination and GlcNAcylation of CHAF1A regulates HIV-1 latency and reactivation.
Yang T, Chen M, Zhou M, Deng X, Huang P, Xie S, Zeng J, Luo J, Zhang Y, Ma X, Sun L, Liu J, Zhang H, Li L, Liu B, Qin J, Pan T
Journal of virology 2025 Dec 23;99(12):e0151825
Journal of virology 2025 Dec 23;99(12):e0151825
SLC44A1 deficiency impedes myelin development in the central nervous system.
Chen Q, Chen X, Li Z, Shao Q, Huang H, Zhou W, Qiu M, Su Z, Liu P, He C
Cell reports 2025 Dec 23;44(12):116617
Cell reports 2025 Dec 23;44(12):116617
The protein denitrosylase SCoR2 regulates lipogenesis and fat storage.
Venetos NM, Stomberski CT, Zhou HL, Qian Z, McLaughlin PJ, Bansal PK, Feczko J, Bederman I, Nguyen H, Hausladen A, Schindler JC, Grimmett ZW, Brunengraber H, Premont RT, Stamler JS
Science signaling 2025 Dec 23;18(918):eadv0660
Science signaling 2025 Dec 23;18(918):eadv0660
Loss of ELF2 drives topotecan resistance in retinoblastoma revealed by genome-wide CRISPR-Cas9 screening.
Jiang J, Jiang Z, Luo Q, Chen X, Zhuang J, Chen J, Mu Q, Qiu J, Li Y, Chen S, Zhang P, Yu K, Chen S, Liu GS, Zhuang J
Cell death & disease 2025 Dec 23;17(1):128
Cell death & disease 2025 Dec 23;17(1):128
Identification of senescence-associated drivers of tumour growth and progression using a novel microarray platform.
Ou HL, Hoffmann R, Smith R, Devlin K, Dane M, Muñoz-Espín D, Korkola JE
bioRxiv : the preprint server for biology 2025 Dec 23;
bioRxiv : the preprint server for biology 2025 Dec 23;
The METTL3-YTHDC1 axis mediates architectural RNA m(6)A modification to modulate the integrity of chromatin TADs in MLLr + AML genome.
Fu R, Yu W, Zhao R, Yang H, Cao B, Dai C, Qianjiang H, Xia Y, Wang L, Lu J, Zhou R, Shi A, Lou H, Zhang X, Luo H
Molecular cancer 2025 Dec 22;25(1):22
Molecular cancer 2025 Dec 22;25(1):22
KAT2A affects the inflammatory progression of lupus nephritis through multilevel regulation of cGAS.
Tang Y, Zhang Y, Cao Q, Liu J, Zhuang Q
Journal of molecular medicine (Berlin, Germany) 2025 Dec 22;104(1):11
Journal of molecular medicine (Berlin, Germany) 2025 Dec 22;104(1):11
PAK2 promotes CTC cluster formation by phosphorylating E-cadherin to enhance cell-cell adhesion in breast cancer.
Guo L, Li J, Zhu W, Wang Z, Huang Y, Sun Z, Huang Y, Xu K
Breast cancer research : BCR 2025 Dec 21;28(1):17
Breast cancer research : BCR 2025 Dec 21;28(1):17
[Morinda officinalis polysaccharide delays osteoarthritis mouse chondrocyte degeneration by modulating the glycolysis-pyroptosis axis via targeting the lncRNA XIST].
Fu C, Chen R, Xu S, You J, Lin Q, Huang Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2541-2550
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2541-2550
PLAAT2 facilitates the development of pancreatic cancer and serves as a predictor of resistance to chemotherapy.
Chen Q, Liang T, Wu C, Lu J, Li X, Wan J, Lu Y, Guo Q
BMC cancer 2025 Dec 20;26(1):125
BMC cancer 2025 Dec 20;26(1):125
The Ku80-p53-SIRT1 axis in DNA damage response contributes to sporadic and familial ALS and FTD.
Jun YW, Lee S, Almeida S, Freude KK, Ichida JK, Gao FB
Nature communications 2025 Dec 20;17(1):1007
Nature communications 2025 Dec 20;17(1):1007
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
Zhao C, Liu J, Zhao S, Liu P, Li Z, Li Y, Dong R, Wang XL
Physiological research 2025 Dec 2;74(5):871-884
Physiological research 2025 Dec 2;74(5):871-884
Intestinal clock shapes sleep-wake cycle via sustaining glutamine homeostasis.
Guo L, Xiao Y, Li Z, Huang Y, Cen H, Wu Z, Wang H, Liu X, Yang Z, Zhao C, Hao T, Chen H, Jin M, Lu D, Chen M, Wu B
Cell metabolism 2025 Dec 2;37(12):2423-2437.e6
Cell metabolism 2025 Dec 2;37(12):2423-2437.e6
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
Wu P, Wang S, Hu Z, Zhang H, Lin Y, Li Z, Wu J, Chen Y, Chen Y, Xu Y, Li J, Guan Y
iScience 2025 Dec 19;28(12):113996
iScience 2025 Dec 19;28(12):113996
USP25 deubiquitinates cytosolic METTL3 to impede glioma proliferation via an m6A-independent pathway.
Zhang B, Han W, Gao X, Li W, Yu J, Zhao W, He J, Qiu X, Lu Z, Zhou L, Hu Y, Xie Y, Geng Y, Lu H, Zhao W, Liao X, Chen S, Liu X, Chen S, Tan G, Zhang Y, Wang Z
iScience 2025 Dec 19;28(12):113918
iScience 2025 Dec 19;28(12):113918
Cochlear endoplasmic reticulum stress causes connexin 26 degradation is involved in age-related hearing loss.
Bai X, Liao B, Hu WH, Wang MQ, Sun Y, Chen XB, Xu K
iScience 2025 Dec 19;28(12):113891
iScience 2025 Dec 19;28(12):113891
ZDHHC9 and spermine metabolism: a palmitoylation-driven pathway to prostate carcinogenesis.
Chen C, Zhang Y, Wang G, Liu Y, Ye B, Zhou S, Wang K, Zheng H, Dong X, Luo C, Zhou J, Zeng K, Fang C, Shen L
Journal of translational medicine 2025 Dec 19;24(1):103
Journal of translational medicine 2025 Dec 19;24(1):103
mRNA-lipid nanoparticle vaccines provide protection against lethal Nipah virus infection.
Sun T, Yao Y, Tian C, Peng Y, Liu Y, Gao G, Li Z, Liu H, Han J, Chen M, Xiao S, Yuan Z, Shan C, Liu J, Chen H
NPJ vaccines 2025 Dec 19;11(1):17
NPJ vaccines 2025 Dec 19;11(1):17
Targeting TRIM59 impairs RNA splicing and promotes neuroblastoma differentiation and therapeutic responses.
Zhang Y, Yang Y, Chen G, Yin M, Gao Y, Li Y, Feng H
Journal of experimental & clinical cancer research : CR 2025 Dec 18;45(1):25
Journal of experimental & clinical cancer research : CR 2025 Dec 18;45(1):25
Optogenetic control of biomolecular organization reveals distinct roles of phase separation in RTK signaling.
Zhou M, Shi N, Li P
Cell chemical biology 2025 Dec 18;32(12):1503-1516.e5
Cell chemical biology 2025 Dec 18;32(12):1503-1516.e5
Long noncoding RNA BMPR1B-DT promotes anoikis and reduces proliferation in ovarian cancer.
Li Y, Chen X, Xu Y, Huang S, Zhou C, Tang Z, Liu Y, Chen J, Chen H, Yang Y, He S
BMC cancer 2025 Dec 18;26(1):118
BMC cancer 2025 Dec 18;26(1):118
From Microbiota to Metabolomics: How Corylus heterophylla Fisch. Male Flower Extract Shields Mice from Cognitive Decline.
Lu W, Li Y, Liao X, Hu H, Zhang B, Liang L, Gao H
Nutrients 2025 Dec 18;17(24)
Nutrients 2025 Dec 18;17(24)
Sestrin 2 Regulates Milk Protein Synthesis through a LAT1/mTOR Pathway.
Ke Y, Chen B, Wang X, Jiang X, Liu T, Pan Y, Li Y, Song C, Chen X, Fang X, Wang Y, Zhang C
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31783-31793
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31783-31793
Disrupted inhibin B synthesis due to Sox9 hyper-palmitoylation in Sertoli cells impairs spermatogenesis via paracrine effects.
Xiang Y, Xu Y, Zhang J, Zhu M, He Z, Zang M, Ma R, Chen L, Li Z, Du T, Yao L, Liang K, Shen J, Zhao S, Jing J, Ge X, Yao B
Biological research 2025 Dec 17;59(1):4
Biological research 2025 Dec 17;59(1):4
GALNT3 is a novel target driving lymphomagenesis via O-glycosylation of FGFR2.
Sun R, Wang W, Gao Y, Aximujiang K, Li Y, Innocent A, Xu Z, Ma J
Cell communication and signaling : CCS 2025 Dec 17;24(1):37
Cell communication and signaling : CCS 2025 Dec 17;24(1):37
FTO-mediated m6A modification regulates the osteogenic differentiation of ADSCs by targeting FOXO1.
Wang Z, Wen S, Li H, Wang X, Guo S, Yang S
Stem cell research & therapy 2025 Dec 17;17(1):39
Stem cell research & therapy 2025 Dec 17;17(1):39
Exploring the role of mitochondrial dysfunction-related genes in osteoporosis using weighted gene co-expression network analysis and machine learning.
Zeng HB, Yuan XT, Wu LG, Zhang RK, Yan K, Lai XB, Xu P, Yao XM
European journal of medical research 2025 Dec 16;31(1):103
European journal of medical research 2025 Dec 16;31(1):103
Aluminum exposure induces ferroptosis in spermatogenic cells of mice through iron overload and lipid peroxidation.
Guangji W, Huixin P, Hongfei H, Hai L, Yang F, Shihua L, Yanxin H, Huixiong Y, Wencheng C
Free radical biology & medicine 2025 Dec 16;241:789-806
Free radical biology & medicine 2025 Dec 16;241:789-806
Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy†.
Tang M, Luo M, Zhang L, Xiong L, Gong X, Zhou X, Yang J, Wang P, Zhao Z, Wu S, Xing S, Cai J, Yang X
Biology of reproduction 2025 Dec 16;113(6):1510-1522
Biology of reproduction 2025 Dec 16;113(6):1510-1522
Novel compound heterozygous mutations in plasminogen (p.Gly568Arg/p.Ala620Thr) impair protein structure and function in type II deficiency: mechanistic insights into a hereditary thrombogenic disorder.
Lu Y, Wang F, Yu D, Xie H, Jin Y, Wang M, Yang L
Orphanet journal of rare diseases 2025 Dec 15;20(1):620
Orphanet journal of rare diseases 2025 Dec 15;20(1):620
RHOA regulates mitochondria-ER contact sites through modulation of the VAPB/PTPIP51 tether.
Yang Z, Nakajima S, Chen H, Chakrabarty Y, Feng H, Chan DC
Nature communications 2025 Dec 14;16(1):11260
Nature communications 2025 Dec 14;16(1):11260
HPDA-based tubule-targeting nanoplatform alleviates oxidative stress and ferroptosis for the reversal of renal interstitial fibrosis.
Xiao Z, Luo P, Li G, Tan H, Zhou C, Zeng D, Chen Y, Li Y
Journal of nanobiotechnology 2025 Dec 13;24(1):57
Journal of nanobiotechnology 2025 Dec 13;24(1):57
Human umbilical cord-derived mesenchymal stem cells ameliorate non-alcoholic fatty liver disease via activating TFEB-mediated autophagy in male mice.
Zhang H, Liu P, Deng Y, Wu L, Fan O, Cui Y, Zhang C, Zhu W, Sun YE, Lin C, Wang C
Stem cell research & therapy 2025 Dec 13;17(1):34
Stem cell research & therapy 2025 Dec 13;17(1):34
LAX1 as a core biomarker in Alzheimer's disease and periodontitis via the STAT signaling pathway.
Guo H, Guo T, Wang X, Bao Y, Zhang Z, Xue F, Cheng D
BMC geriatrics 2025 Dec 12;26(1):69
BMC geriatrics 2025 Dec 12;26(1):69
Integrative analysis reveals NFIL3 as a prognostic marker in glioblastoma associated with anesthesia and circadian rhythm genes.
Yuan Y, Lang F, Huang J, Xia Y, Yuan G
Discover oncology 2025 Dec 12;17(1):105
Discover oncology 2025 Dec 12;17(1):105
Low dose IFNγ remodels enhancer landscape to potentiate mesenchymal stromal cell activation.
Lin J, Ruan D, Hu Q, Cao X, Zhou W, Hu S
Stem cell research & therapy 2025 Dec 12;16(1):676
Stem cell research & therapy 2025 Dec 12;16(1):676
The Combined Hypoglycemic Effect of Quercetagetin and Lutein from Marigold and Related Molecular Mechanisms in Mice.
Wang R, Dang C, Gao Z, Wu D, Lian Y, Wang X, Mi S
Foods (Basel, Switzerland) 2025 Dec 12;14(24)
Foods (Basel, Switzerland) 2025 Dec 12;14(24)
The methyltransferase N6amt1 regulates hippocampal neurogenesis through 6 mA modification of Txnrd3 DNA.
Wu Y, Ma W, Li Q, Li Y, Xie L, Kong X, Chen S, Wang Q, Xuan A
Cellular and molecular life sciences : CMLS 2025 Dec 11;83(1):24
Cellular and molecular life sciences : CMLS 2025 Dec 11;83(1):24
Upregulated endoplasmic reticulum oxidoreductin 1-like protein alpha at the mother-fetus interface of preeclampsia promotes trophoblast cell migration and invasion.
Qu T, Li Z, Jia Y, Yang X, He X, Pu R, Yang Q, Ma Q, Wei C, Li Y, Sun X
Gene 2025 Dec 10;973:149825
Gene 2025 Dec 10;973:149825
Circ_0001741 regulates proliferation and invasion in ESCC via the miR-194-5p/E2F3 axis.
Wang Y, Sun Q, Li Z
World journal of surgical oncology 2025 Dec 10;24(1):35
World journal of surgical oncology 2025 Dec 10;24(1):35
MCARE enhances SERCA1 activity in fast-twitch muscle to maintain calcium handling and muscle integrity.
Sasaki T, Takase H, Koebis M, Aiba A, Takahashi Y, Yamauchi Y, Sato R
Nature communications 2025 Dec 10;17(1):629
Nature communications 2025 Dec 10;17(1):629
The SCD5 Gene Modulates Adipogenic Differentiation via the WNT5B Signaling Pathway in Xinjiang Brown Cattle.
Wang Y, Ren W, Shao W, Zhou Y, Liu Y, Cao J, Wang F, Bi J, Yang L
Animals : an open access journal from MDPI 2025 Dec 10;15(24)
Animals : an open access journal from MDPI 2025 Dec 10;15(24)
PML Is Limiting NLRP3 Inflammasome Activity in Human Endothelial Cells.
Liem CH, Steinemann G, Ghiroltean N, Yvonne Y, Sakr H, Nguyen H, Baum O, Berkholz J
Cells 2025 Dec 10;14(24)
Cells 2025 Dec 10;14(24)
Let-7f-5p Inhibits PRRSV Replication by Regulating Lipid Metabolic Reprogramming in Infected Cells.
Jiang D, Huang J, Wang X, Zhao G, Li C, Yang L, Meng X, Xu Q
Veterinary sciences 2025 Dec 10;12(12)
Veterinary sciences 2025 Dec 10;12(12)
Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11.
Miao S, Dai X, Li X, Chen Z, Wang Y, Ye T, Ying Y, Yu Y, Wu A, Song H, Teng P, Ma L, Zheng Q
Cell death discovery 2025 Dec 10;12(1):47
Cell death discovery 2025 Dec 10;12(1):47
Targeting MCM6 Enhances Melphalan Chemosensitivity in Retinoblastoma by Modulating DNA Damage Response.
Wang M, Tang J, Li J, Lv J, Zhang Z, Liu Y, Sun H, Gao Y, Chen S, Tang L, Zhang P, Su S, Lu R
Investigative ophthalmology & visual science 2025 Dec 1;66(15):14
Investigative ophthalmology & visual science 2025 Dec 1;66(15):14
The Actin Histidine methyltransferase SETD3 is a CHD1 lysine di-methyltransferase.
Peng W, Wang C, Yang R, Peng X, Zhao Z, He B, Qing B, Cai Q, Yin W, Chen Y, Yu F, Wang X, Tao Y
Cancer letters 2025 Dec 1;634:218073
Cancer letters 2025 Dec 1;634:218073
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Liu J, Zhang C, Ma R, Yin C, Ren J, Yang S, Zhao Y, Tang Y, Wei J, Li X
Free radical biology & medicine 2025 Dec 1;240:514-531
Free radical biology & medicine 2025 Dec 1;240:514-531
Involvement of Integrin β3 O-Glycosylation in Human Cytomegalovirus Internalization Into Fibroblasts.
Zheng L, Pan T, Wang H, Tian J, He Z
Journal of medical virology 2025 Aug;97(8):e70536
Journal of medical virology 2025 Aug;97(8):e70536
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
Guo J, Wang Y, Yang Y, Feng S, Cai J, Fan S, Wang J, Li N, Qian X, Zhu H
Tissue & cell 2025 Aug;95:102924
Tissue & cell 2025 Aug;95:102924
Functional study of two siblings with isolated growth hormone deficiency and pituitary MR imaging abnormalities caused by a novel HESX1 variant.
Lei N, Yang Y, Liu Y, Hu R, Li C, Lu W
Endocrine 2025 Aug;89(2):521-531
Endocrine 2025 Aug;89(2):521-531
ZEB1 Contributes to Drug Resistance Through Canonical Wnt Signaling in Lung Cancer.
Shi H, Wang M, Zhao Q, Xu Y
IUBMB life 2025 Aug;77(8):e70053
IUBMB life 2025 Aug;77(8):e70053
The Synergic Inhibition of Wilforlide A With Cisplatin in Lung Cancer Is Mediated Through Caspase-3 and NFκB Signaling.
Peng Z, Xiao X, Lu X, Cao D, Fang H, Yang Z, He D
IUBMB life 2025 Aug;77(8):e70043
IUBMB life 2025 Aug;77(8):e70043
Mechanism of lncRNA WARS2-IT1 promoting angiogenesis of glioma through miR-299-3P/VEGFA axis and activating PI3K/AKT signaling pathway.
Hu M, Gu W, Huai Y, Wang C, Mei J
Cytotechnology 2025 Aug;77(4):157
Cytotechnology 2025 Aug;77(4):157
The oncogenic role of SPOCK1 in lung carcinoma by promoting immune evasion and its related mechanisms.
Lv G, Chen J, Wei D, Zhang W, Xie W, Yang S
Cytotechnology 2025 Aug;77(4):138
Cytotechnology 2025 Aug;77(4):138
Biodentine Counteracts the Aging Process of Human Dental Pulp Stem Cells Through Wnt/β-Catenin Pathway.
Zhang Q, Cao S, Zhang M, Wu D, Zhang C, Li J
International dental journal 2025 Aug;75(4):100819
International dental journal 2025 Aug;75(4):100819
Targeting ATM enhances radiation sensitivity of colorectal cancer by potentiating radiation-induced cell death and antitumor immunity.
Xie Y, Liu Y, Lin M, Li Z, Shen Z, Yin S, Zheng Y, Zou Y, Zhang Y, Zhan Y, Fang Y, Ding Y
Journal of advanced research 2025 Aug;74:513-530
Journal of advanced research 2025 Aug;74:513-530
Taxifolin Inhibits Platelet Activation and Thrombosis by Regulating the PI3K/Akt and MAPK Signaling Pathways.
Guo F, Yang R, Xiong X, Yuan Y, Zhang L, Hua C, Wu M, Xiao Y, Zhang R, Liu J, Yang Z, Liu G
Molecular nutrition & food research 2025 Aug;69(16):e70129
Molecular nutrition & food research 2025 Aug;69(16):e70129
Prolonged Fructose Overconsumption Activates Original Biosynthetic and Metabolic Pathways of Endogenous Purine in Rats.
Yu Q, Tan W, Ma X, Xu L, Lin G, Cheng J, Xie Q, Liu Y, Li Y, Xian Y, Lin Z, Chen J, Su Z, Yang X, Xie J
Molecular nutrition & food research 2025 Aug;69(16):e70122
Molecular nutrition & food research 2025 Aug;69(16):e70122
SPP1(+) Venous Endothelial Cells and CRABP2(+) Tumor Cells Contribute to Favorable Body and Tail Pancreatic Ductal Adenocarcinoma Tumor Microenvironment.
Liu Y, Fu Y, Liu T, Wang J, Zhang Z, Shi Y, Cao Z, Yang G, Chen H, Luo W, Tao J, Wang Y, Weng G, Zhang M, Ye L, Xiao J, Qiu J, Zhang T, Huang H
Molecular carcinogenesis 2025 Aug;64(8):1377-1391
Molecular carcinogenesis 2025 Aug;64(8):1377-1391
α-Enolase and γ-Enolase Expression in Enriched S- and N-Type SH-SY5Y Cells: Regulatory Role of Cathepsin X.
Horvat S, Zidar N, Kos J, Pišlar A
Molecular neurobiology 2025 Aug;62(8):10006-10019
Molecular neurobiology 2025 Aug;62(8):10006-10019
Ginsenoside Rg1 mitigates myocardial ischemia/reperfusion injury by inhibiting NLRP3-mediated pyroptosis.
Li QH, Shen JX, Xu SL, Zhang KZ
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):825-837
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):825-837
IFIT3 inhibits transmissible gastroenteritis virus (TGEV) infection by promoting the phosphorylation of TBK1 and STAT1, which enhances the innate immune response.
Chen G, Yang J, He H, Wu J, Yu H, Li S, Yang N, Huang X, Wang C, Zhang T, Li M, Li B, Fu Y, Liu G
Virology 2025 Aug;609:110574
Virology 2025 Aug;609:110574
METTL1-driven epitranscriptomic enhancement of TXNDC12 boosts c-Myc stability through USP5 in HNSCC.
Mai Z, Zheng J, Lu Y, Lin P, Lin Y, Zheng Y, Chen X, Guo B, Cui L, Zhao X
Experimental & molecular medicine 2025 Aug;57(8):1743-1758
Experimental & molecular medicine 2025 Aug;57(8):1743-1758
The role of microparticles in oxidative stress and inflammation in patients with vascular intimal hyperplasia.
Wang XL, Han WQ, Yang K, Chang FJ, Zhang W, Li Z, Yang YJ
The Journal of international medical research 2025 Aug;53(8):3000605251364781
The Journal of international medical research 2025 Aug;53(8):3000605251364781
Cadmium treatment induces oxidative damage and apoptosis in vitro skeletal muscle cells.
Wenhong L, Yang J, Zhao Y, Zhang N, Zhao B, Rongxian L, Shiyan G, Zuoshun H
Toxicology 2025 Aug;515:154139
Toxicology 2025 Aug;515:154139
MLKL triggers NLRP3 activation in sodium arsenite-induced myocardial necroinflammation.
Cui Y, Zhang M, Xiao Y, Liu J, Chen Y, Ruan X, Zhao X, Liu Y, Shi Y, Tian J, Li L, Zhang X, Jia M, Wang Y, Yang X, Lin Z, Chen J
Toxicology 2025 Aug;515:154132
Toxicology 2025 Aug;515:154132
An engineered M2 macrophage-derived exosomes-loaded electrospun biomimetic periosteum promotes cell recruitment, immunoregulation, and angiogenesis in bone regeneration.
Wen Z, Li S, Liu Y, Liu X, Qiu H, Che Y, Bian L, Zhou M
Bioactive materials 2025 Aug;50:95-115
Bioactive materials 2025 Aug;50:95-115
Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration.
Li W, Shen Q, Tong T, Tian H, Lian X, Wang H, Yang K, Dai Z, Li Y, Chen X, Wang Q, Yang D, Wang F, Hao F, Wang L
Bioactive materials 2025 Aug;50:475-493
Bioactive materials 2025 Aug;50:475-493
SGLT2i continuously prevents cardiac hypertrophy by reducing ferroptosis via AMPK up-regulation.
Zhao BB, Wang J, Zhang LL, Li C, Xue HH, Zhao L, Han QH, Shi HT
Molecular and cellular biochemistry 2025 Aug;480(8):4849-4864
Molecular and cellular biochemistry 2025 Aug;480(8):4849-4864
Fibroblast Growth Factor 21 Confers Protection Against Asthma Through Inhibition of NLRP3 Inflammasome Activation.
Liu Y, Li J, Wu Z, Wu S, Yang X
Inflammation 2025 Aug;48(4):2720-2731
Inflammation 2025 Aug;48(4):2720-2731
CircIRAK3 Promotes Neutrophil Extracellular Trap Formation by Improving the Stability of ELANE mRNA in Sepsis.
Lu Y, Wu H, Luo Y, Xia W, Sun D, Chen R, Miao Z, Zhang W, Yu Y, Wen A
Inflammation 2025 Aug;48(4):2503-2515
Inflammation 2025 Aug;48(4):2503-2515
S100A9 Inhibition Mitigates Acute Pancreatitis by Suppressing RAGE Expression and Subsequently Ameliorating Inflammation.
Shou C, Sun Y, Zhang Q, Zhang W, Yan Q, Xu T, Li H
Inflammation 2025 Aug;48(4):2355-2366
Inflammation 2025 Aug;48(4):2355-2366
Chronic Arsenic Exposure Causes Alzheimer's Disease Characteristic Effects and the Intervention of Fecal Microbiota Transplantation in Rats.
Li S, Li J, Chen K, Wang J, Wang L, Feng C, Wang K, Xu Y, Gao Y, Yan X, Zhao Q, Li B, Qiu Y
Journal of applied toxicology : JAT 2025 Aug;45(8):1476-1486
Journal of applied toxicology : JAT 2025 Aug;45(8):1476-1486
Yinchenhao Decoction Combined with Praziquantel Ameliorates Inflammation and Hepatic Fibrosis in Schistosoma japonicum-Infected Mice.
Liu JH, Peng M, Chen F, Song QY, Zhang LC, Liao Y, Song LG, Wu ZD
Current medical science 2025 Aug;45(4):944-956
Current medical science 2025 Aug;45(4):944-956
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
Geng X, Li M, Zhang L, Cai Y, Chen X, Mu X, Wang J, Liu B
Oncogene 2025 Aug;44(31):2746-2761
Oncogene 2025 Aug;44(31):2746-2761
β-Catenin interacts with canonical RBPs including MSI2 to associate with a Wnt signalling mRNA network in myeloid leukaemia cells.
Wagstaff M, Sevim O, Goff A, Raynor M, Park H, Mancini EJ, Nguyen DTT, Chevassut T, Blair A, Castellano L, Newbury S, Towler B, Morgan RG
Oncogene 2025 Aug;44(29):2490-2503
Oncogene 2025 Aug;44(29):2490-2503
Ileal FXR Knockdown Ameliorates MASLD Progression in Rats via Modulating Bile Acid Metabolism Mediated by Gut Microbiota.
Wang J, Gao J, Zhang Q, Lu J, Yang Y, Cai X, Dong H, Lu L
Journal of gastroenterology and hepatology 2025 Aug;40(8):2091-2103
Journal of gastroenterology and hepatology 2025 Aug;40(8):2091-2103
Sanguisorba officinalis L. and Sophora japonica L. Inhibit Angiogenesis in Ulcerative Colitis.
Yuzhuo W, Li L, Shu B, Jing Y, Yongqi W, Zhiwei M, Yi X
Journal of gastroenterology and hepatology 2025 Aug;40(8):1991-2006
Journal of gastroenterology and hepatology 2025 Aug;40(8):1991-2006
Danggui Buxue Decoction Combined with Borneol Improves Cyclophosphamide-Induced Myelosuppression by Inhibiting CDK2.
Li K, Wu R, Zhou T, Xiong J
Cancer biotherapy & radiopharmaceuticals 2025 Aug;40(6):426-440
Cancer biotherapy & radiopharmaceuticals 2025 Aug;40(6):426-440
Single-cell sequencing reveals the role of IL-33 (+) endothelial subsets in promoting early gastric cancer progression.
Zhou L, Yang M, Deng C, Hu M, Wu S, Lai K, Zhang L, Chen Z, Tang Q, Wang Q, Chen L, Zha R, Chen Y, Tan Y, He S, Zhou Z
iMeta 2025 Aug;4(4):e70050
iMeta 2025 Aug;4(4):e70050
Eupatilin mitigates ICH-induced brain injury via SOX2/SLC7A11 regulation of ferroptosis.
Shen Y, Wang Y, Liu F
Naunyn-Schmiedeberg's archives of pharmacology 2025 Aug;398(8):10887-10900
Naunyn-Schmiedeberg's archives of pharmacology 2025 Aug;398(8):10887-10900
Novel compound heterozygous MRTFA gene variants cause multiple dysfunctions of neutrophils and autoinflammation.
Li W, Yang L, Yu L, Gan R, Lv G, Tang W, Zhou L, An Y, Zhang Z, Tang X, Li Y, Zhao X
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2025 Aug;36(8):e70171
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2025 Aug;36(8):e70171
Ethanol extract of Sauropus spatulifolius and its active constituents attenuate LPS-induced acute lung injury via NF-κB inhibition and Nrf2 activation.
Zhao L, Du L, Li Y, Guo Y, Pei D, Zhu D, Zhang H
Food science and biotechnology 2025 Aug;34(12):2947-2957
Food science and biotechnology 2025 Aug;34(12):2947-2957
Honokiol rescues progranulin deficiency in pathogen-induced and genetically driven neurodegeneration: Bridging veterinary models with therapeutic development.
Cao Z, He W, Hu R, Chen Y, Xue J, Gao F, Lan Y
Veterinary microbiology 2025 Aug;307:110616
Veterinary microbiology 2025 Aug;307:110616
Silencing PIM1 inhibits ENO1-induced AKT activation and attenuates fibrillogenesis during spinal cord injury-induced skeletal muscle atrophy.
Yu X, Cao J, Wang B, Fu J, Liu J, Sui T, Wang Z, Wu C, Chang J, Cao X, Zhang S
The Journal of biological chemistry 2025 Aug;301(8):110398
The Journal of biological chemistry 2025 Aug;301(8):110398
A novel programmed cell death signature predicts clinical outcomes in clear cell renal cell carcinoma and identifies PLK1 as a therapeutic target.
Tan HT, Ma CY, Sun CH, Sun SZ, Zhang MX, Wang JF
Apoptosis : an international journal on programmed cell death 2025 Aug;30(7-8):1797-1825
Apoptosis : an international journal on programmed cell death 2025 Aug;30(7-8):1797-1825
Role and mechanism of RPA1 in the development and progression of glioma.
Zhao Z, Sun Y, Yin P, Zhang Q, Zhang J
Experimental and therapeutic medicine 2025 Aug;30(2):163
Experimental and therapeutic medicine 2025 Aug;30(2):163
Paeoniflorin protected UVA-exposed skin fibroblasts from caspase-3/GSDME mediated pyroptosis.
Shi D, Chu H, Sun Y, He H, Huang W, Pan H, Ma C, Yao S, Shi M, Wang H, Wu Y
Journal of photochemistry and photobiology. B, Biology 2025 Aug;269:113188
Journal of photochemistry and photobiology. B, Biology 2025 Aug;269:113188
The pathogenicity of a novel frame-shift variant c.2321delC of PROM1 in an autosomal recessive cone-rod dystrophy pedigree may be associated with augment of autophagy.
Wu C, Zhang L, Guo Q, Li Y, Qiu R, Yao S, Lei B
Experimental eye research 2025 Aug;257:110453
Experimental eye research 2025 Aug;257:110453
MiR-223-3p inhibits hippocampal neurons injury and exerts anti- anxiety/depression-like behaviors by directly targeting NLRP3.
Wang W, Yang T, Liu N, Yang L, Liu C, Qi X, Wang N, Wang M, Wang Y
Psychopharmacology 2025 Aug;242(8):1797-1809
Psychopharmacology 2025 Aug;242(8):1797-1809
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Li J, Zeng S, Zhou B, Yan Q, Sun Y, Chen L, Zhang E, Li J
Biochemical pharmacology 2025 Aug;238:116980
Biochemical pharmacology 2025 Aug;238:116980
Astrocytic AEG-1 drives neuroinflammation and enhances seizure susceptibility.
Chen Y, Yu Y, Kou J, Qi H, Zhang C, Wang F, Zhou L, Liang X, Xu K, Zhang C, Zhang A, Liu X, Zhang C, Gan G, Sun J, Zhu X
Neurobiology of disease 2025 Aug;212:106957
Neurobiology of disease 2025 Aug;212:106957
p66shc exacerbates the progression of obstructive nephropathy through apoptosis, mitochondrial damage, and EMT.
Gao X, Fan X, Yu X, Wang R, Zhang B, Li Y, Liu X, Yang Y
Journal of pediatric urology 2025 Aug;21(4):834-843
Journal of pediatric urology 2025 Aug;21(4):834-843
P2X7 receptor is essential for ST36-attenuated cardiac fibrosis upon beta-adrenergic insult.
Zhang T, Lv J, Liu ZY, Lei QL, Jiang ZF, Sun XX, Yue X, Li X, Zhu KL, Yang YK, Luo L, Cao X
Purinergic signalling 2025 Aug;21(4):637-649
Purinergic signalling 2025 Aug;21(4):637-649
CD19(+)IL-10(+) regulatory B cells induced by IL-12p35 regulates functional T-cell subsets in patients with immune thrombocytopenia.
Hua F, Sun L, Li Y, Meng Y, Fan X, Wang X, Lu Y, Cheng Y, Li F
British journal of haematology 2025 Aug;207(2):369-380
British journal of haematology 2025 Aug;207(2):369-380
Molecular mechanism for the interaction of MOG1 with the intracellular loop II of cardiac sodium channel Na(v)1.5 and its role in arrhythmias.
Bai X, Wang Z, Xiong H, Yan C, Yao Y, Xu C, Li H, Wang QK
Journal of molecular and cellular cardiology 2025 Aug;205:68-83
Journal of molecular and cellular cardiology 2025 Aug;205:68-83
Excessive ultra-processed foods exposure aggravates ulcerative colitis via macrophage ferroptosis.
Pang X, Yan J, Lv X, Wang J, Chen Q, Qi Y, Xu X, Wang B, Cao H
Environment international 2025 Aug;202:109706
Environment international 2025 Aug;202:109706
The Long Noncoding RNA TUG1 Is Down-Regulated in Osteonecrosis of the Femoral Head and Enhances the Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by Stimulating the Wnt/β-Catenin Pathway.
Duan X, Zhang J, Zhao Y, Liu G, Wu Z, Wu Z, Lei Y, Xing F, Cao R, Li H, Kong N, Liu C, Li Y, Tian R, Wang K, Yang P
The American journal of pathology 2025 Aug;195(8):1523-1536
The American journal of pathology 2025 Aug;195(8):1523-1536
Cilostazol attenuates vascular inflammation via the regulation of TICAM1/IRF3 signaling pathway.
Chiu HW, Shih CC, Huang HJ, Huang TH, Sung LC
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Aug;189:118275
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Aug;189:118275
Tumor necrosis factor alpha-induced activation of SREBP2 promotes cholesterol biosynthesis in cholestasis.
Xu Z, Cao X, Zhu Z, Lei J, Li L, Zhang X, Chai J
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Aug;1870(6):159642
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Aug;1870(6):159642
ARHGAP11A is a potential prognostic biomarker and therapeutic target for pancreatic adenocarcinoma.
Shu QA, Huang XD, Wu J, Liang XR, Wang YL, Yu JM, Wang ZW, Liu N, Wang JH, Xie N
The international journal of biochemistry & cell biology 2025 Aug;185:106804
The international journal of biochemistry & cell biology 2025 Aug;185:106804
Rhynchophylline as an agonist of sirtuin 3 ameliorates endothelial dysfunction via antagonizing mitochondrial damage of endothelial progenitor cells.
Lin L, Sun B, Hu Y, Yang W, Li J, Wang D, Zhang L, Lu M, Li Y, Li Y, Zhang D, Li C
British journal of pharmacology 2025 Aug;182(15):3476-3502
British journal of pharmacology 2025 Aug;182(15):3476-3502
Dysregulation of CRY1 impairs brain thyroid hormone pathway and promotes anxiety-like behavior in male mice.
Lv B, Liu Y, Yang Y, Wu Y, Chen Z, Zhang T, Yu F, Shi Y
Metabolism: clinical and experimental 2025 Aug;169:156292
Metabolism: clinical and experimental 2025 Aug;169:156292
Irg1 mediates inhibition of A20-triggered NF-κB signaling cascade in tilapia macrophages during early immune response.
Li J, Wu Z, Zeng Q, Zhang T, Wang Y, Yang Y, Guo Z, Ye J, Han B
Developmental and comparative immunology 2025 Aug;169:105411
Developmental and comparative immunology 2025 Aug;169:105411
Mechanism of sulforaphane in treatment of pancreatic cancer cell based on network pharmacology and in vitro experiments.
Ren Z, Feng J, Yang M, Feng D, Wang X, Liu W
Bioorganic chemistry 2025 Aug;163:108754
Bioorganic chemistry 2025 Aug;163:108754
A novel designed fully peptide-based PROTAC, FPP29, demonstrates its potent cytotoxic effects to liver cancer HCCLM3 cells by targeting FOXM1.
Jia S, Qi H, Shang Z, Hua X, Liang A, Tian Y, Wu D, Jiang Y, Liu X, Mao C
Bioorganic chemistry 2025 Aug;163:108626
Bioorganic chemistry 2025 Aug;163:108626
Exogenous Nucleotides Supplementation Attenuates Age-Related Sarcopenia.
Wu X, Liu R, Zhu N, Wang X, Wei C, An X, Xu M, Li Y
Journal of cachexia, sarcopenia and muscle 2025 Aug;16(4):e70002
Journal of cachexia, sarcopenia and muscle 2025 Aug;16(4):e70002
Analysis of hepatitis B virus integration identifies KMT2B as a novel cancer-related gene in pancreatic cancer.
Li M, Li H, Liu D, Liu S, Yuan H, Wu Y, Du M, Fang Y, Li J, Cong H, Zhao D, Fan C, Wang Q, Shen C, Gan Y, Sun Y, Tu H
Clinical and translational medicine 2025 Aug;15(8):e70424
Clinical and translational medicine 2025 Aug;15(8):e70424
Unveiling the renoprotective mechanisms of self-assembled herbal nanoparticles from Scutellaria barbata and Scleromitrion diffusum in acute kidney injury: A nano-TCM approach.
Xia L, Yang Q, Fu K, Yang Y, Ding K, Huo Y, Zhang L, Li Y, Zhu B, Li P, Huo Y, Sun L, Liu Y, Zhang H, Liu T, Shan W, Zhang L
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4265-4284
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4265-4284
Deciphering the prognostic signature of nonsmall cell lung cancer using cisplatin resistance and circulating tumor cell-related gene analysis.
Gao L, Sun X, Wang L, Gao K, Yu L, Wang Y
3 Biotech 2025 Aug;15(8):259
3 Biotech 2025 Aug;15(8):259
Curdione inhibits the proliferation of human uterine leiomyomas by targeting YTHDF1.
Yang X, Zuo J, Qiu T, Ren H, Qian R, Luo W, Chen Z, Li D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156938
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156938
Diosgenin promoted OPCs differentiation via blocking GLUR2/GAPDH interaction in a pilocarpine rat model of epilepsy.
Gao Z, Wang L, Lai Q, Liu Y, Wang S, Liu J, Feng Z, Liu H, Yao R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156921
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156921
USP5-Rich Apoptotic Extracellular Vesicles Regulate Nucleus Pulposus Cells Apoptosis and DNA Damage Repair by Preventing E2F1 Proteasomal Degradation.
Shi P, Gao H, Cheng Z, Wu W, Zhang A, Chen X, Wu W, Zhang Y
Journal of extracellular vesicles 2025 Aug;14(8):e70148
Journal of extracellular vesicles 2025 Aug;14(8):e70148
Modulating intracellular calcium dynamics with alkaloids: A novel strategy against oxidative neurodegeneration.
Niğdelioğlu Dolanbay S
Toxicology research 2025 Aug;14(4):tfaf100
Toxicology research 2025 Aug;14(4):tfaf100
Diminution of HSP75 disrupts intestinal epithelial barrier by inciting mPTP opening in ulcerative colitis.
Liang H, Bai X, Zhu R, Song H, Miao Y, Wen Y, Niu J, Zhang F
Cellular signalling 2025 Aug;132:111837
Cellular signalling 2025 Aug;132:111837
HnRNPR promotes non-small cell lung cancer progression by protecting XB130 mRNA from XRN1- and DIS3L2-mediated degradation.
Wang QR, Liu LL, Gou XJ, Liu Y, Zhao Y, Zhang T, Jiang YH, Zhou JJ, Li JL, Zhang J, Xie Y
Cellular signalling 2025 Aug;132:111816
Cellular signalling 2025 Aug;132:111816
Hedgehog pathway inhibitor HhAntag suppresses virus infection via the GLI-S1PR axis.
Zhang J, Dong C, Chen Z, Hua R, Li Z, Lin Y, Wang Y, Feng T, Dai J
Cellular signalling 2025 Aug;132:111807
Cellular signalling 2025 Aug;132:111807
GRHL3 specifically initiated by the TP63 transcription factor promotes the metastasis of squamous cell carcinogenesis.
Bai H, Wei X, Yan X, Wei S, Dai S, Wang D, Xue Y, Jana D, Gao F, Zhou W, Zhao L
Cellular signalling 2025 Aug;132:111794
Cellular signalling 2025 Aug;132:111794
RUNX1 Is an Independent Prognostic Marker Involved in Immune Infiltration and Therapeutic Responses in Clear Cell Renal Cell Carcinoma Patients Through Cluster Regulation With RUNX2.
Jian J, Zhang J, Xu H, Wang H, Hou J
Immunity, inflammation and disease 2025 Aug;13(8):e70242
Immunity, inflammation and disease 2025 Aug;13(8):e70242
Tongue squamous cell carcinoma-derived exosomes miR-21-5p affect tumor progression via promoting M2 macrophage polarization.
Xu Z, Fang X, Wang S, Mu J, Gai Q, Chen Y, Sun Z, Zhai J
Non-coding RNA research 2025 Aug;13:184-196
Non-coding RNA research 2025 Aug;13:184-196
Gut microbiota promote the propagation of pathologic α-syn from gut to brain in a gut-originated mouse model of Parkinson's disease.
Wu J, Li CS, Huang WY, Zhou SY, Zhao LP, Li T, Li MA, Zhang MX, Qiao CM, Zhao WJ, Cui C, Shen YQ
Brain, behavior, and immunity 2025 Aug;128:152-169
Brain, behavior, and immunity 2025 Aug;128:152-169
Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models.
Yang RZ, Li F, Liu J, Li SA, Liu DH, Wu Z, Liu PP, Liu W, Zhou B, Jiang C, Zhang H, Yu Y, Kang JS
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e07210
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e07210
UTX Responds to Nanotopography to Suppress Macrophage Inflammatory Response by Remodeling H3K27me3 Modification.
Jia H, Zhang H, Mo D, Xie B, Qiao H, Chen T, Song H, Xu X, Yang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e05723
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e05723
LIMK1 as a Novel Kinase of β-Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5.
Li SJ, Liang ZR, Liu ZC, Luo XP, Li JY, Yu XM, Huang XZ, He Y, Xu TY, Xu JJ, Peng SC, Song YX, He Y, Zhuang XW, Zheng CC, Zhang F, Lam AK, Dai W, He ML, Liu B, Zhao Q, Lu GL, Liu JB, Wang ZN, Li ZG, Liu ZX, Xu WW, Li B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e03223
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e03223
ALKBH5 mediates FGF21 m6A demethylation in human bone marrow mesenchymal stem cells under high glucose conditions.
Wang Z, Tang Y, Liu Y, Zeng Y, Zhang M
Biochemical and biophysical research communications 2025 Aug 8;774:152042
Biochemical and biophysical research communications 2025 Aug 8;774:152042
ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation.
Zhang W, Ren W, Guo S, Han H, Cai W, Bai H, Li L, Jiang X, Zheng X, Zhang T, Wang Y, Ye H, Cao H, Shi W, Zhou H, Yu Z, Qin L, Jiao Z
Cell death & disease 2025 Aug 8;16(1):597
Cell death & disease 2025 Aug 8;16(1):597
The Key Flavor Substance in Zanthoxylum Preventing Alzheimer's Disease through Insulin Signaling.
Wang H, Wu D, Jiang Y, Jia G, Xiao Q, Liang H, Ma N, Hu B, Zhao R, Lv H, Ma Y, Wei DQ, Zheng L, Xiao Z
Journal of agricultural and food chemistry 2025 Aug 6;73(31):19631-19641
Journal of agricultural and food chemistry 2025 Aug 6;73(31):19631-19641
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats.
Yang JJ, Xu SW, Zhang XY, Mao WF, Wu YF
Bone & joint research 2025 Aug 6;14(8):685-695
Bone & joint research 2025 Aug 6;14(8):685-695
Camellia japonica Flower Extract and the Active Constituent Hyperoside Repair DNA Damage Through FUNDC1-Mediated Mitophagy Pathway for Skin Anti-Aging.
Gao H, Shi J, Li G, Lai Z, Liu Y, Yuan C, Mei W
Antioxidants (Basel, Switzerland) 2025 Aug 6;14(8)
Antioxidants (Basel, Switzerland) 2025 Aug 6;14(8)
SCAP Interacts with Trim27 to Promote Vascular Neointimal Hyperplasia by Regulating the Stability and Ubiquitination of IκBα.
Yao Y, Wang X, Xuan C, Li D, Huang W, Wei L, Ruan XZ, Li D, Chen Y
Aging and disease 2025 Aug 6;
Aging and disease 2025 Aug 6;
Exploring the functional and prognostic roles of EPHX4 in pancreatic cancer: Insights from bioinformatics and experimental validation.
Huang S, Gu D, Xiong W
Gene 2025 Aug 5;959:149504
Gene 2025 Aug 5;959:149504
Glucuronolactone improves lung injury caused by PRRSV and DON co-challenge by enhancing the Nrf2-mediated antioxidant capacity in weaning piglets.
Hou J, Cui C, Wu J, Tian M, Lu Q, Liu S, Ye G, Tian C, Tang J, Gao K, Wang L, Jiang Z, Qiu Y, Yang X
Veterinary research 2025 Aug 5;56(1):161
Veterinary research 2025 Aug 5;56(1):161
RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation.
Chen Z, Gu X, Chen H, Zhang H, Liu J, Yang X, Cai Y, Zhang M, Yan L, Yang Y, Shan B, Zhu ZJ, Zhang Y, Gu J, Xu D
Cell metabolism 2025 Aug 5;37(8):1732-1749.e9
Cell metabolism 2025 Aug 5;37(8):1732-1749.e9
Analysis of the prognostic and immune role of MCM6 in pan-cancer and experimental validation in lung adenocarcinoma cells.
Liao M, Li C, Lv J, Yang R, Li J, Wu K, Zhang J, Zhu Q, Shi Y, Zhang X
Scientific reports 2025 Aug 5;15(1):28648
Scientific reports 2025 Aug 5;15(1):28648
Molecular mechanisms of cryoablation-mediated lung cancer suppression unveiled by non-coding RNA regulatory network profiling.
Wang X, Zhang M, Liu D, Lin S, Zhang Y, Li Q
Scientific reports 2025 Aug 5;15(1):28627
Scientific reports 2025 Aug 5;15(1):28627
Complement Receptor 3 Regulates Microglial Exosome Release and Related Neurotoxicity via NADPH Oxidase in Neuroinflammation Associated with Parkinson's Disease.
Ma Y, Zhang X, Xu J, Luo R, Li S, Su H, Wang Q, Hou L
Antioxidants (Basel, Switzerland) 2025 Aug 5;14(8)
Antioxidants (Basel, Switzerland) 2025 Aug 5;14(8)
miR-30a enhanced RIG-I-mediated type I interferon antiviral response by targeting USP14.
Zhang J, Wang Y, Sun N, Zou B, Wang Z, Yin H, Xie J, Xia B, Sun N
Microbiology spectrum 2025 Aug 5;13(8):e0018825
Microbiology spectrum 2025 Aug 5;13(8):e0018825
Phospholipase Cε1 activates Rap1 signaling pathway to promote proliferation, EMT and angiogenesis of choriocarcinoma cells.
Wang D, Liu C, Tian C, Fang J, Ye K
Molecular biology reports 2025 Aug 4;52(1):790
Molecular biology reports 2025 Aug 4;52(1):790
Aggregation potency and proinflammatory effects of SARS-CoV-2 proteins.
Costa M, Wang DW, Zhao KD, Yuan L, Krisko A, Li JY, Outeiro T, Li W
Scientific reports 2025 Aug 4;15(1):28446
Scientific reports 2025 Aug 4;15(1):28446
Trimethylamine N-oxide Induced Chronic Kidney Injury by Triggering PANoptosis.
Shao D, Bai L, Chen Q, Chen Y, Qiu Z, Liu Y, Jin S, Wu Y, Dai J
Physiological research 2025 Aug 31;74(4):613-622
Physiological research 2025 Aug 31;74(4):613-622
Role of Carvedilol in Inhibiting the Proliferation and Migration of Vascular Smooth Muscle Cells by Upregulating microRNA-145 Expression.
Yang G, Zhang Z, Ma X, Chen J, Shi H, Yang J, Han Q
Physiological research 2025 Aug 31;74(4):577-588
Physiological research 2025 Aug 31;74(4):577-588
CDK11 Mediates Autophagy to Promote Breast Cancer Cell Proliferation and Migration by Regulating BCL-2.
Zhou Y, Zhu L, Yang K, Yang J, Wang D, Zhang W, Zhang J, Zhang A, Duan Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70997
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70997
Galnt4 Knockdown Modulates Lysosomal Function to Reduce Foam Cell Formation and Attenuate Atherosclerotic Plaque Progression.
Teng D, Jia W, Che H, Chen H, He X, Gong L, Dong H, Song J, Pan Y, Wang H, Yang J, Zhong L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70931
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70931
25HC Depleted PMs-Accessible Cholesterol to Restrict SFTSV Entry and Infectious-EVs Mediated Infection.
Zhang R, Li L, Li S, Yin S, Cheng M, Jing N, Li J, Wu Z, Wu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70839
Lipid metabolites as biomarkers and therapeutic targets in oral squamous cell carcinoma.
Ma H, Liu C, Li X, Zuo L, Li C, Xu X, Zhang S, Ma X, Yue E, Qiao B, Wang Y, Chen W, Sun Z, Zhao H
BMC oral health 2025 Aug 31;25(1):1390
BMC oral health 2025 Aug 31;25(1):1390
Role of the transcription factor SOX8 in hepatocellular carcinoma development and lymph node metastasis.
Teng X, Li TM, Peng K, Li YH, Zhang HJ, Ge B, Xie HX, Yang KJ, Qin CJ, Liao XW, Zhu GZ, Zhou X, Peng T
Translational cancer research 2025 Aug 31;14(8):4882-4905
Translational cancer research 2025 Aug 31;14(8):4882-4905
Identification and validation of a novel lymph node metastasis-related model for papillary thyroid carcinoma to predict the prognosis.
Xie CR, Zhang XW, Chen Q, Zhao LF, Huang KM, Wang Y, Yu X
Gland surgery 2025 Aug 31;14(8):1456-1472
Gland surgery 2025 Aug 31;14(8):1456-1472
IRAK-M regulates NTHi-induced inflammation via JNK and NF-κB signal pathways.
Hou H, Li J, Huang Y, Zhao Y, Gao J
Biochemical and biophysical research communications 2025 Aug 30;776:152229
Biochemical and biophysical research communications 2025 Aug 30;776:152229
Engineered MAP30ER: A plant toxin-derived platform for EGFR-Targeted delivery of protein and chemotherapeutic payloads.
Li Y, Chen L, Sun Q, Zhao J, Wang F
Biochemical and biophysical research communications 2025 Aug 30;776:152184
Biochemical and biophysical research communications 2025 Aug 30;776:152184
Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.
Zhang L, Chen W, Huang W, Cheng H
Frontiers in bioscience (Landmark edition) 2025 Aug 30;30(8):42844
Frontiers in bioscience (Landmark edition) 2025 Aug 30;30(8):42844
Comprehensive bioinformatic analysis identifies potential therapeutic drugs for CryAB (R120G)-related cardiomyopathy.
Zheng J, Liu Y, Wang J, Hu J, Qiu W, Su M
BMC cardiovascular disorders 2025 Aug 30;25(1):643
BMC cardiovascular disorders 2025 Aug 30;25(1):643
M1-BMDMs with Wnt5a deletion attenuate liver fibrosis by suppression of Wnt5a/Frizzled 2 axis in hepatic progenitors.
Xing FF, Wang DY, Xu YN, Zheng XR, Zhang SH, Zong MY, Zhan JY, Wang DX, Liu W, Chen JM, Chen GF, Liu P, Liu CH, Mu YP
Cell & bioscience 2025 Aug 30;15(1):125
Cell & bioscience 2025 Aug 30;15(1):125
Sex-dependent behavioral and neuronal alterations in the F2 generation of a neurodevelopmental mouse model for schizophrenia.
Wang YC, Huang YY, E ED, Fu CX, Li JW, Mi YW, Zhong N, Yang FR, Zhang T, Xu LM, Zhang XQ
Progress in neuro-psychopharmacology & biological psychiatry 2025 Aug 30;141:111476
Progress in neuro-psychopharmacology & biological psychiatry 2025 Aug 30;141:111476
Non-SMC condensin I complex subunit H promotes cell proliferation and inhibits cell apoptosis of clear cell renal cell carcinoma by activating the PI3K/AKT pathway.
Ha H, Wang J, Zhang X, Du Y, Xiong W, Li S, Shang P
Translational andrology and urology 2025 Aug 30;14(8):2153-2170
Translational andrology and urology 2025 Aug 30;14(8):2153-2170
OTUB2/NR4A1 restrains the development of preeclampsia by suppressing macrophage M1 polarization.
Wang Y, Wang Y, Tong F, Gao Q, Li B, Zhao Y
Communications biology 2025 Aug 29;8(1):1304
Communications biology 2025 Aug 29;8(1):1304
Jianpi Huayu Jiedu Decoction prevents the progression of H. pylori and MNU-induced gastric precancerous lesions by inhibiting ferroptosis and remodeling linoleic acid metabolism.
Zhang S, Xiao Y, Xie Z, Liu S, Li J, He P, Lai Y, Yin Y, Lin H, Pan H, Fang C
Journal of ethnopharmacology 2025 Aug 29;352:120217
Journal of ethnopharmacology 2025 Aug 29;352:120217
Mechanisms and synergistic effects of the active components of Xanthocerais lignum in inhibiting rheumatoid arthritis through the modulation of the biological behavior of synovial cells.
Qian H, Bai C, Jia X, Yang Y, Tian X, Wang X
Journal of ethnopharmacology 2025 Aug 29;352:120200
Journal of ethnopharmacology 2025 Aug 29;352:120200
A Dual-Specificity d-Peptide Antagonist of MDM2 and MDMX for Antitumor Immunotherapy.
Liao C, Yan J, Tolbert WD, Chen X, Pazgier M, Lu W, Zhan C, Lu W
Journal of medicinal chemistry 2025 Aug 28;68(16):16940-16957
Journal of medicinal chemistry 2025 Aug 28;68(16):16940-16957
Activated Schwann cells promote tumor growth in colon cancer.
He K, Wang H, Wu H, Li W, Huo R, Jiang L, Yu M, Xue J
Cancer letters 2025 Aug 28;626:217791
Cancer letters 2025 Aug 28;626:217791
Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics.
Zou F, Jin Y, Zhang Z, Zhang Y, Wang M, Zhu F, Qiu J, Ye H, Fu Y, Ping H
Journal of translational medicine 2025 Aug 28;23(1):967
Journal of translational medicine 2025 Aug 28;23(1):967
Bleomycin promotes cellular senescence and activation of the cGAS-STING pathway without direct effect on fibrosis in an idiopathic pulmonary fibrosis model.
Miura Y, Milad N, Takata A, Kanazawa S
Aging 2025 Aug 28;17(8):2189-2211
Aging 2025 Aug 28;17(8):2189-2211
Enhanced BEST2 expression in keratinocytes alleviates psoriatic inflammation.
Ma L, Wang J, Li D, Wen Y
International immunopharmacology 2025 Aug 28;161:115077
International immunopharmacology 2025 Aug 28;161:115077
High ELK3 expression is associated with the wild type IDH1 in glioma and enhances infiltration of M2 macrophages.
Xin Z, Guo Y, Zhou Q, Wang L, Liu W, Jiang X, Ren C
International immunopharmacology 2025 Aug 28;161:115064
International immunopharmacology 2025 Aug 28;161:115064
HERC5 induces podocyte injury in LN by mediated IRF3 ISGylation to promote the production and overactivation of IFN-β in podocytes.
Wei Q, Wang LW, Zhao J, Dong Y, Miao XY, Tian YX, Liu JX, Feng XJ, Liu SX, Liu QJ, Zhang W
International immunopharmacology 2025 Aug 28;161:115059
International immunopharmacology 2025 Aug 28;161:115059
S100a8 inhibitor Paquinimod attenuates coal dust-induced pulmonary fibrosis via blocking neutrophils-S100a8-Tlr4-macrophages signaling axis.
Du M, Hu S, Cao W, Li B, Jin H, Wang F, Yan R, Li X, Xie Z, Zou Y, Tao X, Wang W, Li Y, Mu M
International immunopharmacology 2025 Aug 28;161:115020
International immunopharmacology 2025 Aug 28;161:115020
Novel therapeutic approach in periodontitis: Sulforaphane attenuates disease progression via Nrf2-mediated antioxidant defense.
Liu Y, Li T, Liao Y, Chen J, Sheng Y, Zhao Y, He Z, Tang H, Wang Y, Bian Z, Ji Y
International immunopharmacology 2025 Aug 28;161:115002
International immunopharmacology 2025 Aug 28;161:115002
HADHB mediates 5-fluorouracil sensitivity in colorectal cancer.
Zhang X, Jin H, Li D, Liu J, Han J
Discover oncology 2025 Aug 28;16(1):1648
Discover oncology 2025 Aug 28;16(1):1648
The study of JAZF1-mediated apoptosis of decidual stromal cells by activating the NF-κB signaling pathway in spontaneous preterm birth.
Gong MQ, Hu YY, Zhang YQ, Wang XD
BMC pregnancy and childbirth 2025 Aug 27;25(1):891
BMC pregnancy and childbirth 2025 Aug 27;25(1):891
CircCRIM1 promotes the translation of HIF-1α protein through its interaction with PTBP3 and enhances malignant progression and angiogenesis in glioblastoma.
Liu Y, Luo Y, Song D, Meng W, Bai J, Li Y, Lin X, Wang J, Fan D, Gu Y
Biochemical pharmacology 2025 Aug 27;242(Pt 1):117279
Biochemical pharmacology 2025 Aug 27;242(Pt 1):117279
Solanum lyratum-Derived Solalyraine A1 Suppresses Non-Small Cell Lung Cancer Through Regulation of Exosome Secretion and Related Protein Biomarkers.
Jiang P, Liu L, Chen L, Han B, Du X
Pharmaceuticals (Basel, Switzerland) 2025 Aug 27;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Aug 27;18(9)
MSC-derived exosomes improve endometrial fibrosis via the lncRNA IGF2R/ miR-143-5p/AQP8 axis.
Huo X, Chen J, Qian M, Xue Q, Xu P, Wang Y, Jiang Z, Luo Q, Xiong Y
Stem cell research & therapy 2025 Aug 27;16(1):464
Stem cell research & therapy 2025 Aug 27;16(1):464
DHRS9 promotes malignant progression of ovarian cancer through SQSTM1.
Wu Y, Meng S, Zhao H, Tan B, Gao J, Du J, Meng X
Journal of cancer research and clinical oncology 2025 Aug 27;151(8):236
Journal of cancer research and clinical oncology 2025 Aug 27;151(8):236
Degraded Polysaccharides from Noni (Morinda citrifolia L.) juice Mitigate Glucose Metabolism Disorders by Regulating PI3K/AKT-Nrf2-GSK3β Signaling Pathways in HepG2 Cells.
Wei X, Du P, Luo Y, Zhao Y, Zhou X, Chen G, Zhang B
Foods (Basel, Switzerland) 2025 Aug 27;14(17)
Foods (Basel, Switzerland) 2025 Aug 27;14(17)
Extracellular matrix stiffness reduces DNA 6 ma level to facilitate colorectal cancer progression via disrupting P53 binding to CDKN1A promoter.
Xie SA, Li X, Yin MY, Du F, Zhang ST, Zhu ST
Experimental hematology & oncology 2025 Aug 27;14(1):111
Experimental hematology & oncology 2025 Aug 27;14(1):111
NOLC1 suppresses immunochemotherapy by inhibiting p53-mediated ferroptosis in gastric cancer.
Zhao S, Lin J, Zhu B, Jin Y, Dong Q, Ruan X, Jin D, Yi Y, Bai B, Li H, Liang D, Lu J, Meng L, Wang X, Cui Y, Gu Y, Shen X, Lu X, Rao S, Sun W
eLife 2025 Aug 27;13
eLife 2025 Aug 27;13
PRMT2-mediated upregulation of miR-323-3p in sensory neurons promotes trigeminal neuropathic pain by targeting Kv2.1 channels.
Qi R, Tao Y, Wang S, Zhou Y, Sun Y, Jiang D, Huang Z, Chen G, Zhao G, Zhang Y, Rui Y, Tao J
Cell reports 2025 Aug 26;44(8):116028
Cell reports 2025 Aug 26;44(8):116028
A multifaceted strategy for intra- and extracellular nucleic acid regulation to alleviate intervertebral disc degeneration.
Zhao L, Liang K, Cheng W, Zhou X, Yang L, Mao X, Qi W, Jin H, Zhang W, Pan H, Wang D
Nature communications 2025 Aug 26;16(1):7936
Nature communications 2025 Aug 26;16(1):7936
Conditional immortalization of mesenchymal stem cells and their extracellular vesicles therapy for interstitial cystitis/bladder pain syndrome.
Liao G, Long C, Guo R, Wang S, Han R, Yang J, Liu J
Stem cell research & therapy 2025 Aug 26;16(1):459
Stem cell research & therapy 2025 Aug 26;16(1):459
Spautin-1 inhibits the growth of diffuse large B-cell lymphoma by inducing mitochondrial damage-mediated PANoptosis and anti-tumor immunity.
Wu J, Deng Y, Gao Y, Wei B
Cancer immunology, immunotherapy : CII 2025 Aug 25;74(9):293
Cancer immunology, immunotherapy : CII 2025 Aug 25;74(9):293
Sodium-glucose cotransporter 2 inhibitors alleviate renal fibrosis in diabetic kidney disease by inhibiting Hmgcs2 and Btg2 in proximal tubular cells.
Yan S, Luo M, Zhou R, Peng F, Zhang M, Feng Y, Zhao L, Yang L, Cheng Y
Journal of translational medicine 2025 Aug 25;23(1):959
Journal of translational medicine 2025 Aug 25;23(1):959
Ultrasound-actuated platelet mimetic nanomotors enable targeted piezocatalytic ROS storm for precision thrombolysis.
Zhao Y, He J, Liu Y, Soummane H, Ran P, Yang Q, Gao X, Cao W, Zhao L
Journal of nanobiotechnology 2025 Aug 25;23(1):585
Journal of nanobiotechnology 2025 Aug 25;23(1):585
African swine fever virus A179L inhibits interferon induced transmembrane protein 1 activation of NF-κB pathway.
Sun X, Zhu L, Mou C, Zhao J, Go YY, Shi K, Chen Z
Cell communication and signaling : CCS 2025 Aug 25;23(1):380
Cell communication and signaling : CCS 2025 Aug 25;23(1):380
Systems Network Integration of Transcriptomic, Proteomic, and Bioinformatic Analyses Reveals the Mechanism of XuanYunNing Tablets in Meniere's Disease via JAK-STAT Pathway Modulation.
Jin Z, Wang C, Gao Y, Tao X, Wu C, Guo S, Huang J, Zhou J, Qiao C, Chai K, Chang H, Li C, Zou X, Wu J
Pharmaceuticals (Basel, Switzerland) 2025 Aug 25;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Aug 25;18(9)
Heat shock protein family H member 1 HSPH1 expression correlates with progression and prognosis of hepatocellular carcinoma.
Huang T, Xu S, Li M, Lu C, Zhang J
Scientific reports 2025 Aug 24;15(1):31151
Scientific reports 2025 Aug 24;15(1):31151
CAF-derived exosomes drive the FGF4/SHH feedback loop by encapsulating GREM1 in non-small cell lung cancer.
Wu X, Chen W, Fang T, Chen Z, Fang S, Zhou C
Molecular medicine (Cambridge, Mass.) 2025 Aug 23;31(1):281
Molecular medicine (Cambridge, Mass.) 2025 Aug 23;31(1):281
NLRP3 promotes NK cell-mediated cytotoxicity and inhibits colorectal cancer development via the NKG2D signaling pathway.
Xu C, Qian W, Wu Y, Chen X, Li Z, Xu D
Journal of molecular histology 2025 Aug 22;56(5):277
Journal of molecular histology 2025 Aug 22;56(5):277
Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation.
Fang R, Bai L, Verheijen BM, Li B, Dong K, Paulo JA, Zhou M, Chu YC, Song Y, Sherman MY, Gygi S, Field CM, Mitchison TJ, Lu Y
Nature communications 2025 Aug 22;16(1):7852
Nature communications 2025 Aug 22;16(1):7852
Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1.
Guo H, Zhang H, Zhang C, Shen Y, Jiang L, Yang M, Zhang Y, Zhang N, Zhang R, Yu R, Yang Y, Tian X
JCI insight 2025 Aug 22;10(16)
JCI insight 2025 Aug 22;10(16)
VILMIR is a trans-acting long noncoding RNA that enhances the host interferon response in human epithelial cells.
John K, Smith E, Istishin A, Mahmood N, Diveley K, Tollison TS, Carpenter S, Peng X
bioRxiv : the preprint server for biology 2025 Aug 22;
bioRxiv : the preprint server for biology 2025 Aug 22;
FBXO42 promotes hepatocellular carcinoma progression via mediating p57Kip2 ubiquitination and degradation.
Zhou B, Wu S, Hong S, Li H, Jiang Z, Sun Y, Qiu J, Qin L
European journal of medical research 2025 Aug 21;30(1):784
European journal of medical research 2025 Aug 21;30(1):784
mRNA decapping enzyme2 DCP2 expression correlates with progression and prognosis of hepatocellular carcinoma.
Huang T, Wang R, Lu C, Zhang J
Scientific reports 2025 Aug 21;15(1):30818
Scientific reports 2025 Aug 21;15(1):30818
Collagen alpha-5(IV) chain activation by nuclear factor 1/C promotes nasopharyngeal carcinoma progression.
Cao Y, Wang P, Li P, Wei K, Kang X, Han X, Huai D, Fei B
Human cell 2025 Aug 20;38(5):148
Human cell 2025 Aug 20;38(5):148
Drug-Free Approach to Regulate Undruggable Proto-Oncogene MYC Using Biomimetic Porous Nanoparticles for Cancer Immunotherapy.
Happonen E, Dang Y, Wang J, Saarela S, Sivonen M, Zakir M, Laari MI, Constantinou Y, Tamarov K, Hakkarainen H, Montaser AB, Leinonen H, Küblbeck J, Örd T, Taipale M, Kaikkonen M, Liu R, Klefström J, Yu H, Xu Z, Lehto VP, Xu W
ACS applied materials & interfaces 2025 Aug 20;17(33):46521-46534
ACS applied materials & interfaces 2025 Aug 20;17(33):46521-46534
Isorhamnetin protects against D-GalN/LPS-induced acute liver injury in mice through anti-oxidative stress, anti-inflammation, and anti-apoptosis.
Long L, Zhang M, Qin HZ, Xu LB, Wang BB, Wu WY, Zhu H, Lin S
BMC complementary medicine and therapies 2025 Aug 2;25(1):297
BMC complementary medicine and therapies 2025 Aug 2;25(1):297
Gut-resident Phascolarctobacterium succinatutens decreases fat accumulation via MYC-driven epigenetic regulation of arginine biosynthesis.
Lan Q, Liufu S, Chen B, Wang K, Chen W, Xiao L, Liu X, Yi L, Liu J, Xu X, Liu C, Liu M, Yin Y, Ma H
NPJ biofilms and microbiomes 2025 Aug 2;11(1):150
NPJ biofilms and microbiomes 2025 Aug 2;11(1):150
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
He C, Tang C, Guo J, Yin X, Zhu Q, Fang C
Journal of translational medicine 2025 Aug 19;23(1):939
Journal of translational medicine 2025 Aug 19;23(1):939
Targeting ATF4-DDIT4/TXNIP induced mitochondrial dysfunction and ferroptosis: ISRIB as novel therapy for septic cardiomyopathy.
Chen Y, Feng X, Li Z, Wang X, Xiong W, Liu J, Wang G, Xu W, Jin R, Zhang L, Qian Z
Journal of translational medicine 2025 Aug 19;23(1):938
Journal of translational medicine 2025 Aug 19;23(1):938
Gut-derived Faecalibaculum rodentium exerts anti-cancer effects on colorectal cancer by modulating PDPN-CLEC-2 signaling pathway.
Yang X, Liu M, Wang T, Ma X, Guan Z, Ma B, Duan X, Su C
mSystems 2025 Aug 19;10(8):e0014825
mSystems 2025 Aug 19;10(8):e0014825
Establishment and evaluation of a patient-derived organoids-based xenograft model of primary aldosteronism using [(18)F]AlF-NOTA-pentixather PET/CT: bridging preclinical and clinical imaging.
Zhang X, Mou T, Wang Y, Miao Q, Wang W, Sun Z, Bo Y, Cui J, Zhao J, Li M, Hong B, Mi H, Zhang N
Journal of translational medicine 2025 Aug 18;23(1):927
Journal of translational medicine 2025 Aug 18;23(1):927
AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria.
Chen L, Liu Y, Zhang J, Song T, Wu J, Ren Z
Cell death & disease 2025 Aug 18;16(1):623
Cell death & disease 2025 Aug 18;16(1):623
CD99 is a potential diagnostic and immunological biomarker in pan-cancer.
Jiang J, Han Z, Zhang H, Chen H
Discover oncology 2025 Aug 18;16(1):1574
Discover oncology 2025 Aug 18;16(1):1574
FEN1 plays a key role in the transition from HSIL to CSCC.
Zhang F, Chen X, Chu C, Chen M, Yang Y, You Y, Zhou J, Jiang P, Song N, Yu Y, Liu Y
Scientific reports 2025 Aug 17;15(1):30122
Scientific reports 2025 Aug 17;15(1):30122
CDKN1A and EGR1 are key genes for endoplasmic reticulum stress-induced ferroptosis in MASH.
Xu Q, Chen Y, Zhang H, Zhou K, Zhao Y, Deng W, Wang Z, Guo L, Liu H, Ren Z, Liu L, Tang Z, Jiang Z
Free radical biology & medicine 2025 Aug 16;236:188-203
Free radical biology & medicine 2025 Aug 16;236:188-203
Cholecystectomy-related gut microbiota dysbiosis exacerbates colorectal tumorigenesis.
Tang B, Li S, Li X, He J, Zhou A, Wu L, Xiao X, Wang S, Jiang H, Jian J, Hou Z, Ge Y, Lei Y, Zhou J, Tu D, Lu C, Yang M, Yang S
Nature communications 2025 Aug 16;16(1):7638
Nature communications 2025 Aug 16;16(1):7638
Nintedanib inhibits neovascularization and subretinal fibrosis in a laser-induced choroidal neovascularization mouse model.
Qin S, Zhu Y, Liu Y, Xie H, Zhang J, Zhang C, Xu G
Biochemical and biophysical research communications 2025 Aug 15;775:152169
Biochemical and biophysical research communications 2025 Aug 15;775:152169
Cu(OH)(2) nanopesticide induced liver dysfunction in mice by targeting lipoylated tricarboxylic acid cycle proteins via ferredoxin 1.
Ren Z, Ren M, Ling W, Ren D, Liang J, Cai Y, Wang X, Wang S, Duan Y, Ku T, Ning X, Sang N
Journal of hazardous materials 2025 Aug 15;494:138403
Journal of hazardous materials 2025 Aug 15;494:138403
NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing.
Meng N, Li L, Yang X, Tang H, Wang J, Zhang S, Xia Z, Yao J, Zhang Q, Hu C, Su C, Duan R
iScience 2025 Aug 15;28(8):113113
iScience 2025 Aug 15;28(8):113113
P75(NTR) activation limits CD21(lo) B cell subsets expansion in response to autoimmune-inducing challenges.
Luo C, Zha AH, Luo RY, Hu ZL, Shen WY, Dai RP
iScience 2025 Aug 15;28(8):113055
iScience 2025 Aug 15;28(8):113055
LncRNA SNHG5 modulates cell proliferation and migration through the miR-92a-3p/BTG2 axis in gastric cancer by the PI3K/AKT pathway.
Mao QQ, Zhang ML, Zhong L, Xu XD, Wang XH, Pan DY, Zhou FS, Huang JX, Zhao XG, Chen JJ, Jiang XY, Sun X, Ding WQ
World journal of gastrointestinal oncology 2025 Aug 15;17(8):105321
World journal of gastrointestinal oncology 2025 Aug 15;17(8):105321
Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3.
Lyu XJ, Zhou L, Jiang XM, Zheng D
World journal of gastrointestinal oncology 2025 Aug 15;17(8):105006
World journal of gastrointestinal oncology 2025 Aug 15;17(8):105006
Synthesis of USP5-IN-1 derivatives as novel USP5 inhibitors with potent activity against cholangiocarcinoma cells.
Hu X, Yu Z, Zhu H, Cui H, Ning F, Dai J, Zhang J, Li Y, Zhang X
Bioorganic & medicinal chemistry 2025 Aug 15;126:118213
Bioorganic & medicinal chemistry 2025 Aug 15;126:118213
Granzyme B as a potential biological target in toxic encephalopathy: A big data-based exploratory analysis.
Liu L, Wang J, Liu C
Medicine 2025 Aug 15;104(33):e43879
Medicine 2025 Aug 15;104(33):e43879
Mitochondrial-dependent apoptosis and STAT3 activation induced by oxidative stress in pemphigus vulgaris.
Liang JP, Xu JM, Ou YJ, Xu YJ, Wu SM, Chen JB
Scientific reports 2025 Aug 14;15(1):29900
Scientific reports 2025 Aug 14;15(1):29900
A novel neutrophil extracellular trap-related gene signature for predicting glioblastoma prognosis.
Huang C, Yu XB, Zhou YZ
Scientific reports 2025 Aug 14;15(1):29838
Scientific reports 2025 Aug 14;15(1):29838
Circadian Rhythm Cascade SIRT1/PGC-1α/BMAL1 Pathway Regulates Nitroglycerin-Induced Chronic Migraine.
Liu W, Liu Z, Dong H, Ni Z, Wang Y, Li Y, Qian H, Hu Y, Zuo Y
Neurochemical research 2025 Aug 13;50(4):262
Neurochemical research 2025 Aug 13;50(4):262
Integrative analysis and experimental validation identify the role of CD44 and Nucleolin in regulating gliogenesis following spinal cord injury.
Shi M, Sun Y, Ding L, Li X, Xu Q, Wei F, Gao T, Deng DYB
Cell regeneration (London, England) 2025 Aug 13;14(1):35
Cell regeneration (London, England) 2025 Aug 13;14(1):35
The Hsp40 co-chaperone DNAJC7 modifies polyglutamine but not polyglycine aggregation.
Ramani B, Ehsani K, Kampmann M
bioRxiv : the preprint server for biology 2025 Aug 12;
bioRxiv : the preprint server for biology 2025 Aug 12;
A rapid and efficient red-light-activated Cre recombinase system for genome engineering in mammalian cells and transgenic mice.
Zhou Y, Wei Y, Yin J, Kong D, Li W, Wang X, Yao Y, Huang Q, Li L, Liu M, Qiao L, Li H, Zhao J, Zhong TP, Li D, Duan L, Guan N, Ye H
Nucleic acids research 2025 Aug 11;53(15)
Nucleic acids research 2025 Aug 11;53(15)
Analysis of the Role of KLF4 in the Regulation of Porcine Epidemic Diarrhea Virus Infection.
Wang H, Zhou Y, Gu S, Feng M, Wang J, Jin J, Huang X, Wu S, Bao W
Animals : an open access journal from MDPI 2025 Aug 11;15(16)
Animals : an open access journal from MDPI 2025 Aug 11;15(16)
Celastrol Activates SIRT1/PGC-1α/Nrf2 Axis to Inhibit Oxidative Damage for Subconjunctival Fibrosis Alleviation.
Guo Z, Feng H, Sun X, Yang L, Ning Q, Deng Y, Li Z, Li J
Investigative ophthalmology & visual science 2025 Aug 1;66(11):70
Investigative ophthalmology & visual science 2025 Aug 1;66(11):70
Estrogen increases Setdb1 cytoplasmic localization to stabilize Serpinh1 and improve protein homeostasis in osteoblasts.
Han C, Wang P, Ye J, Wang R, Shi X, Hu G, Hu X, Shen J, Zhang M, Zhang X, Wu Y
Molecular and cellular endocrinology 2025 Aug 1;605:112568
Molecular and cellular endocrinology 2025 Aug 1;605:112568
Intranasal administration of exosomes derived from adipose mesenchymal stem cells ameliorates depressive-like behaviors and inhibits inflammation via AMPK/mTOR-mediated autophagy.
Sun S, Rong J, Wang C, Li R, Zhang H, Wang W, Duan H, Nie Z, Xiang D, Liu Z
Journal of affective disorders 2025 Aug 1;382:227-247
Journal of affective disorders 2025 Aug 1;382:227-247
Stage-dependent efficacy of short-chain fatty acids in amyotrophic lateral sclerosis: Insights into autophagy and neuroprotection.
Xin Z, Xin C, Huo J, Liu Q, Dong H, Li X, Liu Y, Li R
Life sciences 2025 Aug 1;374:123686
Life sciences 2025 Aug 1;374:123686
Pericyte loss: a key factor inducing brain Aβ40 accumulation and neuronal degeneration in cerebral amyloid angiopathy.
Liu T, Guo W, Gong M, Zhu L, Cao T, Huang Y, Yang Y, Chen J, Yang C, Zhang S, Zhang J, Lü T
Experimental brain research 2025 Aug 1;243(8):191
Experimental brain research 2025 Aug 1;243(8):191
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
Zhang E, Wang Y, Zhang H, Li X, Su Y, Cui J, Xu R, Mao X, Sang M, Lin Z, Zhou X
Free radical biology & medicine 2025 Aug 1;235:231-247
Free radical biology & medicine 2025 Aug 1;235:231-247
MSC-derived exosomes alleviate oxidative stress-induced lysosomal membrane permeabilization damage in degenerated nucleus pulposus cells via promoting m6A demethylation of Nrf2.
Gao X, Jia S, Gao L, Chen S, Zhang Y, Liang X, Zhang L, Zhang B, Meng C
Free radical biology & medicine 2025 Aug 1;235:213-230
Free radical biology & medicine 2025 Aug 1;235:213-230
AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis.
Qiu R, Yang M, Jin X, Liu J, Wang W, Zhang X, Han J, Lei B
Neural regeneration research 2025 Aug 1;20(8):2408-2419
Neural regeneration research 2025 Aug 1;20(8):2408-2419
Flavonoid Extract of Senecio scandens Buch.-Ham. Ameliorates CTX-Induced Immunosuppression and Intestinal Damage via Activating the MyD88-Mediated Nuclear Factor-κB Signaling Pathway.
Zhu X, Zhang L, Ni X, Guo J, Fang Y, Xu J, Chen Z, Hao Z
Nutrients 2025 Aug 1;17(15)
Nutrients 2025 Aug 1;17(15)
USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment.
Han S, Cui L, Wang B, Ruan Y, Shi M, Hong C, Guan X, Chen Z, Li Y, Liao Y, Ma M, Lu X, Wang H, Zhang Y, Liu C
Cancer immunology research 2025 Aug 1;13(8):1226-1245
Cancer immunology research 2025 Aug 1;13(8):1226-1245
Panobinostat potentiates adagrasib-induced cell death by triggering autophagy in human non-small cell lung cancer.
Lu H, Fu W, Xia Y, Yan Y, Shu C, Chen Y, Xu C, Zheng P, Shen X, Cui R, Zou P, Ni D
Cell death discovery 2025 Aug 1;11(1):360
Cell death discovery 2025 Aug 1;11(1):360
Hua Yu Xiao Zheng decoction induces ectopic endometrial stromal cell senescence via inhibiting the PI3K/AKT signaling.
Xu Y, Li Y, Zhang J, Cai P
Tissue & cell 2025 Apr;93:102763
Tissue & cell 2025 Apr;93:102763
CNPY2 modulates senescence-associated secretory phenotype in tendon stem/progenitor cells.
Xu G, Wang Y
Tissue & cell 2025 Apr;93:102706
Tissue & cell 2025 Apr;93:102706
Klotho improves Der p1-induced bronchial epithelial cell damage by inhibiting endoplasmic reticulum stress to regulate mitochondrial function.
Wang C, Liu Z, Xie X, Li Y, Sun L
Tissue & cell 2025 Apr;93:102646
Tissue & cell 2025 Apr;93:102646
Key role of the CSE/transsulfuration pathway in macrophage phenotypic change under iron overload.
Yuan Z, Chen Y, Xin Y, Zhang Y, Dong Z, Wang J, Wang X, Yang G, Li S
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Apr;88:127611
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Apr;88:127611
Cordycepin Ameliorates Kainic Acid-Induced HT22 Cell Neurotoxicity by Activating GPR120-Mediated Mitophagy.
San Y, Wang M
Developmental neurobiology 2025 Apr;85(2):e22961
Developmental neurobiology 2025 Apr;85(2):e22961
Esketamine alleviated cardiomyocyte ferroptosis induced by oxygen-glucose deprivation/reoxygenation (OGD/R) via cyclic GMP-AMP synthase interactor.
Ouyang J, Xiao W, Wu D, Bai M, Zhao Q, Li Y
Cytotechnology 2025 Apr;77(2):57
Cytotechnology 2025 Apr;77(2):57
Co-delivery of fucoxanthin and Twist siRNA using hydroxyethyl starch-cholesterol self-assembled polymer nanoparticles for triple-negative breast cancer synergistic therapy.
Wu Z, Tang Y, Liu Y, Chen Z, Feng Y, Hu H, Liu H, Chen G, Lu Y, Hu Y, Xu R
Journal of advanced research 2025 Apr;70:463-479
Journal of advanced research 2025 Apr;70:463-479
BEND6 promotes RNA viruses' replication by inhibiting innate immune responses.
Chen T, Ding L, Tu S, Sun H, Zou J, Ouyang A, Jiang M, Feng Y, Jin M, Chen H, Zhou H
Science China. Life sciences 2025 Apr;68(4):1073-1083
Science China. Life sciences 2025 Apr;68(4):1073-1083
Generation of Myeloid-Specific Bmal1 Knockout Mice and Identification of Bmal1-Regulated Ferroptosis in Macrophages.
Chen Q, Wang W, Fang W, Qin L, Wang J, Huang X, Pan S, Zheng R
Genesis (New York, N.Y. : 2000) 2025 Apr;63(2):e70014
Genesis (New York, N.Y. : 2000) 2025 Apr;63(2):e70014
BTK and YKL-40 Levels and Their Association with Acute AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder.
Liu J, Wang G, Shi M, Guo RY, Yuan C, Wang Y, Mehmood A, Zhang L, Li B
Molecular neurobiology 2025 Apr;62(4):4785-4801
Molecular neurobiology 2025 Apr;62(4):4785-4801
A Novel Heterozygous IHH c.331_333del Mutation Identified in a Fetus with Brachydactyly Type A1 Causes IHH Protein Maturation Failure in HEK293T Cells.
Zhu T, Guan L, Chen D, Luo Y, Zhu M, Sun R, Shi J, Wang Q, Chen Y, Wang Y, Wang H, Lu Z, Wang D
Phenomics (Cham, Switzerland) 2025 Apr;5(2):123-136
Phenomics (Cham, Switzerland) 2025 Apr;5(2):123-136
EGFR tyrosine kinase inhibitor ZZC4 overcomes acquired resistance to gefitinib.
Attiogbe MKI, Huang TT, Zhao HY, Wang HY, Cao L, Yan PP, Zhang SQ, Cao YX
Toxicology and applied pharmacology 2025 Apr;497:117280
Toxicology and applied pharmacology 2025 Apr;497:117280
PRMT5 Inhibition Enhances Therapeutic Efficacy of Cisplatin via Mediating miR-29b-3p-Mcl-1 Expression in Lung Adenocarcinoma.
Li H, Fan J, Shen W, Zhang Y, Zhu X, Li P, Gu Z, Jing P
Cell biology international 2025 Apr;49(4):407-418
Cell biology international 2025 Apr;49(4):407-418
Lactobacillus murinus alleviates insulin resistance via promoting L-citrulline synthesis.
Long J, Shi Z, Miao Z, Dong L, Yan D
Journal of endocrinological investigation 2025 Apr;48(4):1005-1015
Journal of endocrinological investigation 2025 Apr;48(4):1005-1015
TRIM35 Negatively Regulates the cGAS-STING-Mediated Signaling Pathway by Attenuating K63-Linked Ubiquitination of STING.
Zhang J, Wu Y, Wang Y, Wang J, Ye Y, Yin H, Sun N, Qin B, Sun N
Inflammation 2025 Apr;48(2):855-869
Inflammation 2025 Apr;48(2):855-869
TRPV4 drives the progression of leiomyosarcoma by promoting ECM1 generation and co-activating the FAK/PI3K/AKT/GSK3β pathway.
Zhou Q, You Y, Zhao Y, Xiao S, Song Z, Huang C, Qian J, Lu W, Tong H, Zhang Y, Wang Z, Li W, Zhang C, Guo X, Luo R, Hou Y, Cui J, Lu L, Zhou Y
Cellular oncology (Dordrecht, Netherlands) 2025 Apr;48(2):455-470
Cellular oncology (Dordrecht, Netherlands) 2025 Apr;48(2):455-470
Caffeine improves hypoxia/reoxygenation induced neuronal cell injury through inhibiting cellular ferroptosis: an in vitro study.
Jia H, Fan H, Liang J, He R
Neurological research 2025 Apr;47(4):242-250
Neurological research 2025 Apr;47(4):242-250
Differential regulation of pruritic sensation and emotion by cannabinoid type 1 receptors on mPFC glutamatergic and GABAergic neurons.
Zhanmu OY, Yang Y, Feng B, Wang HY, Li H, Zhou HJ, Ge WQ, Wan KX, Wang SX, Zhang KL, Zhang H, Pei L, Pan HL, Tian Q, Li M
Acta pharmacologica Sinica 2025 Apr;46(4):904-921
Acta pharmacologica Sinica 2025 Apr;46(4):904-921
Synergistic restoration of spinal cord injury through hyaluronic acid conjugated hydrogel-polydopamine nanoparticles combined with human mesenchymal stem cell transplantation.
Kao Y, Song W, Zhang R, Gu G, Qiu H, Shen W, Zhu H, Liu Y, Yang Y, Liu H, Zhang Z, Kong X, Feng S
Bioactive materials 2025 Apr;46:569-581
Bioactive materials 2025 Apr;46:569-581
Effects of Huoxue Chubi decoction on protein kinase B-mammalian target of rapamycin autophagy pathway in scleroderma Balb/c model mice.
Xi C, Tiange QU, Hui J, Xingwu D, Jianhong LI, Kaihui Z, Runtian Z, Ruijie W
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Apr;45(2):303-310
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Apr;45(2):303-310
Inhibition of CCN5 Protects Against Apoptosis and Endoplasmic Reticulum Stress in Bisphenol A-Induced Sertoli Cells via p38/JNK MAPK Signaling Pathway.
Zhao L, Wu X, Li Q, Shen Y, Zeng S, Wang J, Liu Q
DNA and cell biology 2025 Apr;44(4):174-185
DNA and cell biology 2025 Apr;44(4):174-185
CBX2 as a therapeutic target in colorectal cancer: insights into the altered chromatin accessibility via RUNX1-CBX2-MAP4K1 axis.
Wang B, Zhang S, Guo Y, Gao W, Wu H, Wang J, Wang Y, Tang C, Liu L
Oncogene 2025 Apr;44(13):909-926
Oncogene 2025 Apr;44(13):909-926
Peroxisomal biogenesis factor 11 as a novel target to trigger lipid biosynthesis and salt stress resistance in oleaginous Tetradesmus obliquus.
Xue Y, Wang W, Sheng X, Zheng Z, Wang Z, Ding F, Li J, Sun Z, Cai Y, Wang X, Xue J
Bioresource technology 2025 Apr;421:132209
Bioresource technology 2025 Apr;421:132209
Iodoacetamide triggers ovarian dysfunction in mice through TGF-β signaling pathway and apoptosis.
Xiao C, Li Q, Li M, Han Y, Xu H, Jiang H, Zhang S, Jin Z, Gao L
Toxicology letters 2025 Apr;406:9-19
Toxicology letters 2025 Apr;406:9-19
Low molecular weight heparins promote migration and invasion of trophoblast cells through regulating the PI3K/AKT signaling pathway.
Zhou Q, Zhao Y, Fu X
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4645-4656
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4645-4656
Prunus mume Alleviates Hyperuricemic Renal Injury: Insights From Network Pharmacology and Experimental Models.
Zheng S, Li S, Diao X, Chen N
Biomedical chromatography : BMC 2025 Apr;39(4):e70035
Biomedical chromatography : BMC 2025 Apr;39(4):e70035
Behavioral, biochemical, and molecular characterization of MPTP/p-intoxicated mice.
Tang X, Xue J, Chen R, Xing J, Lu X, Cui L
Experimental neurology 2025 Apr;386:115168
Experimental neurology 2025 Apr;386:115168
Transcription factor AP-2 Beta, a potential target of repetitive Transspinal magnetic stimulation in spinal cord injury treatment, reduced inflammation and alleviated spinal cord injury.
Yang Y, Shao Y, Dai Q, Zhang Y, Sun Y, Wang K, Xu A
Experimental neurology 2025 Apr;386:115144
Experimental neurology 2025 Apr;386:115144
GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in metabolic dysfunction-associated steatohepatitis livers.
Li YT, Shao WQ, Chen ZM, Ma XC, Yi CH, Tao BR, Zhang B, Ma Y, Zhang G, Zhang R, Geng Y, Lin J, Chen JH
Clinical and molecular hepatology 2025 Apr;31(2):409-425
Clinical and molecular hepatology 2025 Apr;31(2):409-425
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Zhang Y, Lou Q, Lian H, Yang R, Cui R, Wang L, Ma B, Hou L, Jin L, Teng W
Materials today. Bio 2025 Apr;31:101589
Materials today. Bio 2025 Apr;31:101589
Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders.
Tu Y, Zheng W, Ding Z, Xiang J, Yang Q, Liu Y, Cao J, Shen Y, Tang Z, Lin S, Fan L, Xu Y, Chen B
Materials today. Bio 2025 Apr;31:101496
Materials today. Bio 2025 Apr;31:101496
Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN.
Youle RL, Lista MJ, Bouton C, Kunzelmann S, Wilson H, Cottee MA, Purkiss AG, Morris ER, Neil SJD, Taylor IA, Swanson CM
The Journal of biological chemistry 2025 Apr;301(4):108336
The Journal of biological chemistry 2025 Apr;301(4):108336
Lycium barbarum polysaccharide mitigates high-fat-diet-induced skeletal muscle atrophy by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Ren Y, Wang K, Wu Y, Li J, Ma J, Wang L, Zhang C, Li J, Wei Y, Yang Y
International journal of biological macromolecules 2025 Apr;301:140488
International journal of biological macromolecules 2025 Apr;301:140488
The α- to γ-enolase switch: The role and regulation of γ-enolase during oligodendrocyte differentiation.
Horvat S, Fonović UP, Mitrović A, Zidar N, Kos J, Pišlar A
International journal of biological macromolecules 2025 Apr;301:140464
International journal of biological macromolecules 2025 Apr;301:140464
HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3.
Wu N, Sun Q, Yang L, Sun H, Zhou Z, Hu Q, Li C, Wang D, Zhang L, Hu Y, Cong X
International journal of biological macromolecules 2025 Apr;300:140310
International journal of biological macromolecules 2025 Apr;300:140310
Sagittaria sagittifolia polysaccharide extract regulates Nrf2 to improve endoplasmic reticulum stress-mediated apoptosis in rat cataracts and HLEB3 cells.
Zhou MY, Liu BQ, Gao X, Zhang SJ, Jiang Y, Yang T, Sun JB, Zhang X, Liao Y
International journal of biological macromolecules 2025 Apr;300:140270
International journal of biological macromolecules 2025 Apr;300:140270
Carboxymethyl polysaccharides from Poria cocos (Schw.) wolf: Structure, immunomodulatory, anti-inflammatory, tumor cell proliferation inhibition and antioxidant activity.
Liu H, Yang J, Tang Y, Xia X, Lin J
International journal of biological macromolecules 2025 Apr;299:140104
International journal of biological macromolecules 2025 Apr;299:140104
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss.
Wang X, Zheng H, Yang B, Zu M, Wang Z, Zhang J, Zheng F, Yang M, Tong MCF, Zhao L, Bai W
Climacteric : the journal of the International Menopause Society 2025 Apr;28(2):143-153
Climacteric : the journal of the International Menopause Society 2025 Apr;28(2):143-153
Contributing role and molecular basis of Vitamin D/Vitamin D receptor deficiency in hyperhomocysteinemia-induced cardiac hypertrophy.
Qi H, Zhou Y, Hou HT, Wei JH, He GW, Yang Q
Biochemical pharmacology 2025 Apr;234:116812
Biochemical pharmacology 2025 Apr;234:116812
Cross-species analysis of the nuclease Artemis highlights its evolving function in domesticating RAG-like transposons and residues that are crucial for activity.
Huang Z, Cai Z, Tao X, Wang X, Tian X, Chen F, Li Z, Xu A, Yuan S
PLoS biology 2025 Apr;23(4):e3003056
PLoS biology 2025 Apr;23(4):e3003056
Trans 10, cis 12-conjugated linoleic acid alleviates vascular fibrosis in obese mice.
Yu S, Rao Y, Lu J, Li J, Wang B, Gou K
Prostaglandins, leukotrienes, and essential fatty acids 2025 Apr;204:102669
Prostaglandins, leukotrienes, and essential fatty acids 2025 Apr;204:102669
Neutrophil-like cell membrane-coated metal-organic frameworks for siRNA delivery targeting NOX4 to alleviate oxidative stress in acute ischemic injury.
Wang M, Wang Y, Zhang P, Gu C, Zhao X, Gong X, Yang X, Pan J, Xi Y
Acta biomaterialia 2025 Apr;196:487-505
Acta biomaterialia 2025 Apr;196:487-505
Conditional deletion of Pink1 in mesenchymal stem cells suppresses osteogenesis through downregulation of Apoh transcription.
Zhang W, Jiang X, Zhang W, Hou W, Chen M, Chen E, Li W
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167739
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167739
Platelets promote metastasis of intrahepatic cholangiocarcinoma through activation of TGF-β/Smad2 pathway.
Luo G, Zhu S, He L, Liu Q, Xu C, Yao Q, Hu H, Wang Q, Zou S
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167734
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167734
RGFP966 inhibits palmitic acid induced VSMCs phenotypic transition by targeting ATGL.
Zhang S, Nie F, Zeng Y, Yang Z, Song W, Yan X, Tang Z, Fu Y, Guo R
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Apr;1870(3):159597
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Apr;1870(3):159597
Regulation of the EGFR/PI3K/AKT signaling cascade using the Shengui Yangrong Decoction improves ovulation dysfunction and insulin resistance in polycystic ovary syndrome.
An J, Lin T, Guo X, Cao Z, Lu Q
Fitoterapia 2025 Apr;182:106407
Fitoterapia 2025 Apr;182:106407
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
Lin L, Wei J, Xue J, Fan G, Zhu W, Zhu Y, Wu R
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Yue Y, Su L, Wang Y, Li X, Xiao X, Xie J, Yan S
Chinese herbal medicines 2025 Apr;17(2):380-391
Chinese herbal medicines 2025 Apr;17(2):380-391
Amino-modified IONPs potentiates ferroptotic cell death due to the release of Fe ion in the lysosome.
Qi Z, Huang X, Jing J, Feng W, Xu M, Yan L, Gao M, Liu S, Yu XF
Journal of environmental sciences (China) 2025 Apr;150:1-13
Journal of environmental sciences (China) 2025 Apr;150:1-13
PCIF1 drives oesophageal squamous cell carcinoma progression via m6Am-mediated suppression of MTF2 translation.
Li K, Yi Y, Ling R, Zhang C, Zhang Z, Wang Y, Wang G, Chen J, Cheng M, Chen S
Clinical and translational medicine 2025 Apr;15(4):e70286
Clinical and translational medicine 2025 Apr;15(4):e70286
Thermal proteome profiling (TPP) reveals NAMPT as the anti-glioma target of phenanthroindolizidine alkaloid PF403.
Li F, Zhang Z, Shi Q, Wang R, Ji M, Chen X, Li Y, Liu Y, Yu S
Acta pharmaceutica Sinica. B 2025 Apr;15(4):2008-2023
Acta pharmaceutica Sinica. B 2025 Apr;15(4):2008-2023
Targeting ceramide-induced microglial pyroptosis: Icariin is a promising therapy for Alzheimer's disease.
Li H, Xiao Q, Zhu L, Kang J, Zhan Q, Peng W
Journal of pharmaceutical analysis 2025 Apr;15(4):101106
Journal of pharmaceutical analysis 2025 Apr;15(4):101106
Application of 4D-Printed Magnetoresponsive FOGS Hydrogel Scaffolds in Auricular Cartilage Regeneration.
Zhang H, Hua S, He C, Yin M, Qin J, Liu H, Zhou H, Wu S, Yu X, Jiang H, Wang Y, Qian Y
Advanced healthcare materials 2025 Apr;14(9):e2404488
Advanced healthcare materials 2025 Apr;14(9):e2404488
Multi-Omic Insight Into the Molecular Networks in the Pathogenesis of Coronary Artery Disease.
Fang Q, Fan H, Li Q, Zhang M, Zhou Z, Du J, Huang J
Journal of the American Heart Association 2025 Apr;14(7):e037203
Journal of the American Heart Association 2025 Apr;14(7):e037203
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
Jia H, Li J, Chen X, Liu Z, Wu C, Liu C, Zhang J, Luo M, Huang M, Huang S, Cai M, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
Proteomic screening identifies brusatol targets TGFβRII to suppresses non-small cell lung cancer metastasis.
Lin GS, Zheng RQ, Xu ZW, Xing SP, Wu HF, Xie Y, Huang H, Liu YQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156468
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156468
Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα signaling pathway and inhibiting TGF-β1 and FHL1 signaling pathways.
Shi Y, Liu L, Gong Y, Zhang C, Yang Y, Wang W, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156451
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156451
Astaxanthin alleviates spinal nerve ligation-induced neuropathic pain by modulating propionic acid levels.
Li J, Dong D, Sun Y, Wang Q, Li Y, Tao X, Wang K, Zhao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156448
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156448
3-Hydroxypropionaldehyde modulates tryptophan metabolism to activate AhR signaling and alleviate ethanol-induced liver injury.
Liu C, Wang Y, Sheng L, Zhang Y, Luo G, Ruan XZ, Chen Y, Huang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156445
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156445
Canagliflozin-induced renal glutathione distribution mapping in non-diabetic male rat kidneys.
Watanabe G, Horita S, Moriya RF, Masuishi Y, Misaka S, Taira S, Shimomura K, Shimabukuro M, Kazama JJ
Physiological reports 2025 Apr;13(7):e70320
Physiological reports 2025 Apr;13(7):e70320
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Min L, Huo F, Zhu Z, Din L, Zhang L, Xu Y, Xing X, Zhang P, Wang Q
Cellular signalling 2025 Apr;128:111649
Cellular signalling 2025 Apr;128:111649
Deficiency of HSF4 Increases the Secretion of Small Extracellular Vesicles via Upregulation of Chaperone-Mediated Autophagy.
Liu J, Liu X, Xie X, Si W, Zhang Y, Xue M, Peng X, Jiang M, Du S, Shao J, Mao Y, Zhang F, Hu Y
Journal of cellular biochemistry 2025 Apr;126(4):e70031
Journal of cellular biochemistry 2025 Apr;126(4):e70031
Nuclear to Cytoplasmic Transport Is a Druggable Dependency in HDAC7-driven Small Cell Lung Cancer.
Qin T, Wang J, Wang J, Du Q, Wang L, Liu H, Liu W, Li X, Jiang Y, Xu Q, Yu J, Liu H, Wang T, Li M, Huang D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413445
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413445
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Fu Y, Zhu D, Chen X, Qu L, Guo M, Zhang S, Xu G, Chen Z, Li M, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Burn-Induced Gut Microbiota Dysbiosis Aggravates Skeletal Muscle Atrophy by Tryptophan-Kynurenine Mediated AHR Pathway Activation.
Gao S, Leng Y, Qiu Z, Li K, Li J, Peng J, Xie W, Lei S, Xia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2409296
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2409296
Phosphorylation of POU3F3 Mediated Nuclear Translocation Promotes Proliferation in Non-Small Cell Lung Cancer through Accelerating ATP5PF Transcription and ATP Production.
Zeng QG, Li L, Chang T, Sun Y, Zheng B, Xue LN, Liu CL, Li XQ, Huang RT, Gu JX, An ZR, Yao HT, Zhou DY, Fan J, Dai Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411503
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411503
LINC00323 knockdown suppresses the proliferation, migration, and vascular mimicry of non-small cell lung cancer cells by promoting ubiquitinated degradation of AKAP1.
Ke B, Zhong H, Gong Y, Chen X, Yan C, Shi L
Non-coding RNA research 2025 Apr;11:131-140
Non-coding RNA research 2025 Apr;11:131-140
Identifying potential prognosis markers in relapsed multiple myeloma via integrated bioinformatics analysis and biological experiments.
Xu Y, Cao X, Zhou H, Xu H, Chen B, Bai H
Current research in translational medicine 2025 Apr-Jun;73(2):103495
Current research in translational medicine 2025 Apr-Jun;73(2):103495
Ginsenoside Rg1 exerts anti-arrhythmic effect by inhibiting I(CaL) through cAMP-PKA and PI3K-AKT signaling pathways in rat ventricular myocytes after myocardial ischemia-reperfusion injury.
Wang T, Zhao H, Chen Y, Guo S, Zhou C, Cao H, Zou Q, Wang Q
Science progress 2025 Apr-Jun;108(2):368504251341113
Science progress 2025 Apr-Jun;108(2):368504251341113
Lancao decoction alleviates Alzheimer's disease: Depending on activating CaMKII to protect neuronal refunction by reducing β-amyloid in the hippocampus.
Wu L, Sun Y, Zhao L, Xing S, Liu R, Wong NL, Lin Y, Song C, Lu C, Zhang H
Journal of ethnopharmacology 2025 Apr 9;345:119619
Journal of ethnopharmacology 2025 Apr 9;345:119619
Proteomic analysis reveals that Acalypha australis L. mitigates chronic colitis by modulating the FABP4/PPARγ/NF-κB signaling pathway.
Quan X, Miao Z, Han R, Deng R, Cao Y, Tian J, Lu Y, Wang G, Yu X, Wu Y, Dai C
Journal of ethnopharmacology 2025 Apr 9;345:119585
Journal of ethnopharmacology 2025 Apr 9;345:119585
LncRNA H19 inhibited dermal papilla cell senescence process through miR-29a by targeting Wnt/β-catenin signaling pathway.
Liu Z, Li S, Yang Q, Cao G, Yan W, Jiang S, Qiao R, Cai B, Wu Z, Lin C, Zhu N
Archives of dermatological research 2025 Apr 9;317(1):688
Archives of dermatological research 2025 Apr 9;317(1):688
Viral protease binds to nucleosomal DNA and cleaves nuclear cGAS that attenuates type I interferon.
Wu L, Yan Y, Yuan Y, Zhao Z, Qu W, Huang X, Wang H, Li P, Li X
mBio 2025 Apr 9;16(4):e0339524
mBio 2025 Apr 9;16(4):e0339524
The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses.
Sun H, Yang J, Zhang Z, Wu M, Tian Z, Liu Y, Zhang X, Zhong J, Yang S, Chen Y, Luo J, Guan G, Yin H, Niu Q
mBio 2025 Apr 9;16(4):e0267724
mBio 2025 Apr 9;16(4):e0267724
CSF2 promotes chemoresistance in colorectal cancer by regulating Notch pathway.
Zhou H, Gao Z, Wu X, Wang Y, Zhang L
Discover oncology 2025 Apr 9;16(1):495
Discover oncology 2025 Apr 9;16(1):495
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau.
Acosta Ingram D, Turkes E, Kim TY, Vo S, Sweeney N, Bonte MA, Rutherford R, Julian DL, Pan M, Marsh J, Argouarch AR, Wu M, Scharre DW, Bell EH, Honig LS, Vonsattel JP, Serrano GE, Beach TG, Karch CM, Kao AW, Hester ME, Han X, Fu H
Nature communications 2025 Apr 9;16(1):3312
Nature communications 2025 Apr 9;16(1):3312
Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure.
Wang Y, Cheng Y, Sun H, Wang Z, Chen N, Shi C, Liu H, Yang J, Xu Y
Scientific reports 2025 Apr 9;15(1):12106
Scientific reports 2025 Apr 9;15(1):12106
CGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.
Zhang R, Zhong Y, Liu Q, Zhang M, Wang D, Li S, Qi D
Clinical science (London, England : 1979) 2025 Apr 9;139(7):373-387
Clinical science (London, England : 1979) 2025 Apr 9;139(7):373-387
Identification and Functional Analysis of Cystathionine Beta-Synthase Gene Mutations in Chinese Families with Classical Homocystinuria.
Liu X, Liu X, Liu J, Guo J, Nie D, Wang J
Biomedicines 2025 Apr 9;13(4)
Biomedicines 2025 Apr 9;13(4)
Tauroursodeoxycholic Acid Induces Liver Regeneration and Alleviates Fibrosis Through GATA3 Activation.
Bai C, Song X, Yan J, Xu J, Zhou Y, Sun Z, Zheng Q, Zhang Y, Chen R, Jin X, Shao Y, Xie Y, Yang L, Zhong F, Zhang Y, Li J, Li R, Yan S, Li X
Biomedicines 2025 Apr 9;13(4)
Biomedicines 2025 Apr 9;13(4)
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
Thimme Gowda C, Siraganahalli Eshwaraiah M, Wang J, Lim Y, Tomasi ML, Mavila N, Ramani K
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
Fumonisin B1 induces oxidative stress, inflammation and necroptosis in IPEC-J2 cells.
Zou Y, Du X, Zheng X, Mao S, Xu X, Zhang S, Chen X
Veterinary research communications 2025 Apr 8;49(3):161
Veterinary research communications 2025 Apr 8;49(3):161
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis.
Chen C, Chen Z, Luo R, Tu W, Long M, Liang M, Cheng M, Wang Z, Huang K, Wang C
Angiogenesis 2025 Apr 8;28(2):23
Angiogenesis 2025 Apr 8;28(2):23
Iron Homeostasis-Regulated Adaptive Metabolism of PEGylated Ultrasmall Iron Oxide Nanoparticles.
Wang N, Zhou D, Xu K, Kou D, Chen C, Li C, Ge J, Chen L, Zeng J, Gao M
ACS nano 2025 Apr 8;19(13):13381-13398
ACS nano 2025 Apr 8;19(13):13381-13398
Ozone exposure and increased risk of age-related macular degeneration: Evidence from nationwide cohort and toxicological studies.
Zhang G, Qu Y, Wan X, Fang X, Wu Y, Li T, Sun J, Liu X, Xu Y, Luo H, Meng X, Hu W, Chen R, Wu Z, Jia H, Sun X
Innovation (Cambridge (Mass.)) 2025 Apr 7;6(4):100808
Innovation (Cambridge (Mass.)) 2025 Apr 7;6(4):100808
Berberine Alleviates 1-Methyl-3-Nitro-1-Nitrosoguanidine- Induced Chronic Atrophic Gastritis in Rats.
Wang L, Xie L
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(11):723-731
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(11):723-731
Multi-omics analysis of copper metabolism-related molecular subtypes and risk stratification for osteosarcoma.
Zhang Y, Liu W, Liu D, Li X, Zhuang Q, Sun Q, Wu X, Li F
Discover oncology 2025 Apr 7;16(1):480
Discover oncology 2025 Apr 7;16(1):480
SIRT5-mediated BCAT1 desuccinylation and stabilization leads to ferroptosis insensitivity and promotes cell proliferation in glioma.
Wang T, Han XH, Chen JJ, Wang X, Zhang Z, Han XJ, Lu Z
Cell death & disease 2025 Apr 7;16(1):261
Cell death & disease 2025 Apr 7;16(1):261
HNGF6A ameliorates oxidative stress-mediated mitochondrial dysfunction in degenerative meniscus.
Liu R, Du X, Chen Y, Zhu Z, Jiang Z, Zhang C, Jiang D, Zhang Z
Bone & joint research 2025 Apr 7;14(4):318-330
Bone & joint research 2025 Apr 7;14(4):318-330
Metformin attenuated depressive-like behaviors by suppressing TRPV1/NLRP3 mediated neuroinflammation in the hypothalamus of allergic rhinitis mice.
Wang Y, Xie Y, Liu P, Lv H, Guan M, Cong J, Wang Y, Xu Y
Neuroscience 2025 Apr 6;571:52-61
Neuroscience 2025 Apr 6;571:52-61
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Li M, Wang Y, Li X, Xu J, Yan L, Tang S, Liu C, Shi M, Liu R, Zhao Y, Zhang Y, Yang L, Zhang Y, Wang G, Li Z, Guo Y, Feng Y, Liu P
Cell death & disease 2025 Apr 6;16(1):257
Cell death & disease 2025 Apr 6;16(1):257
Targeting the liquid-liquid phase separation of nucleocapsid broadly inhibits the replication of SARS-CoV-2 strains.
Gu L, Wang ZJ, Zhang XR, Liu Y, Zhao M, Jiang SZ, Pan J, Yuan Y, Cai H, Zhou T, Li T, Li TT, Xue W
Biochemical and biophysical research communications 2025 Apr 5;756:151594
Biochemical and biophysical research communications 2025 Apr 5;756:151594
F-53B disrupts energy metabolism by inhibiting the V-ATPase-AMPK axis in neuronal cells.
Zhang Y, Li T, Ding X, Liu L, Ma R, Qin W, Yan C, Wang C, Zhang J, Keerman M, Niu Q
Journal of hazardous materials 2025 Apr 5;487:137111
Journal of hazardous materials 2025 Apr 5;487:137111
Sodium propionate protects against bronchopulmonary dysplasia by inhibiting IL-17-mediated apoptosis of alveolar epithelial cells.
Xie A, Qian W, Ye D, Deng X, Ma Y, Wang R, Zhou Q, Bao Z, Yu R
Scientific reports 2025 Apr 5;15(1):11722
Scientific reports 2025 Apr 5;15(1):11722
Therapeutic Target Discovery for Multiple Myeloma: Identifying Druggable Genes via Mendelian Randomization.
Jiang S, Fan F, Li Q, Zuo L, Xu A, Sun C
Biomedicines 2025 Apr 5;13(4)
Biomedicines 2025 Apr 5;13(4)
Chrysophanol Attenuates Cardiac Fibrosis and Arrhythmia by Suppressing the Endoplasmic Reticulum Stress/Pyroptosis Axis and Inflammation.
Liu C, Qiu S, Liu X, Huang R, Fang Z
Phytotherapy research : PTR 2025 Apr 5;
Phytotherapy research : PTR 2025 Apr 5;
KIF14 plays a role in the regulation of the cell cycle and has implications for prognosis in clear cell renal cell carcinoma.
Wang J, Lai X, Sun Z, Feng S, Li B, Zhao H
BMC urology 2025 Apr 4;25(1):74
BMC urology 2025 Apr 4;25(1):74
Zearalenone Depresses Lactation Capacity Through the ROS-Mediated PI3K/AKT Pathway.
Chen H, Qiu D, Miao X, Yang W, He Q, Ren H, Zhang L, Ruan H, Zhang J, Zhang N
Animals : an open access journal from MDPI 2025 Apr 4;15(7)
Animals : an open access journal from MDPI 2025 Apr 4;15(7)
Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.
Li T, Wang X, Wang J
Physiological research 2025 Apr 30;74(2):287-300
Physiological research 2025 Apr 30;74(2):287-300
The highly expressed GOLPH3 in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance.
Zhu K, Fan J, Cai H, Zhou C, Gong Z, Li Z, Yu J
Journal of gastrointestinal oncology 2025 Apr 30;16(2):415-434
Journal of gastrointestinal oncology 2025 Apr 30;16(2):415-434
The increased matrix stiffness caused by LOXL2 activates Piezo1 channels to promote the migration and invasion of cervical cancer cells.
Liu T, Liang H, Li Y, Liao W, Deng J, Zhang L, Shen F
Discover oncology 2025 Apr 30;16(1):644
Discover oncology 2025 Apr 30;16(1):644
Exposure to MC-LR activates the RAF/ERK signaling pathway, leading to renal inflammation and tissue damage in mice.
Hou Y, Liu Y, Yang Y, Xu S, Yang F
Journal of toxicology and environmental health. Part A 2025 Apr 3;88(7):301-309
Journal of toxicology and environmental health. Part A 2025 Apr 3;88(7):301-309
β-hydroxybutyrate facilitates mitochondrial-derived vesicle biogenesis and improves mitochondrial functions.
Tang M, Tu Y, Gong Y, Yang Q, Wang J, Zhang Z, Qin J, Niu S, Yi J, Shang Z, Chen H, Tang Y, Huang Q, Liu Y, Billadeau DD, Liu X, Dai L, Jia D
Molecular cell 2025 Apr 3;85(7):1395-1410.e5
Molecular cell 2025 Apr 3;85(7):1395-1410.e5
NUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix.
Gao M, Ye P, Zhang Y, Guo Y, Xu J
Carcinogenesis 2025 Apr 3;46(2)
Carcinogenesis 2025 Apr 3;46(2)
Role in Preventing Alcoholic Liver Disease Progression: A Comparative Study of Whole-Component Finger Citron Essential Oil and Its Major Component D-Limonene.
Chen J, Ou G, Gu W, Shi J, Lyu R, Wu X, Wang J, Liu C
Nutrients 2025 Apr 3;17(7)
Nutrients 2025 Apr 3;17(7)
Dietary Fiber Intake Improves Osteoporosis Caused by Chronic Lead Exposure by Restoring the Gut-Bone Axis.
Wang R, Shen J, Han C, Shi X, Gong Y, Hu X, Jia Z, Wang M, Wu Y
Nutrients 2025 Apr 29;17(9)
Nutrients 2025 Apr 29;17(9)
The autocrine motility factor receptor delays the pathological progression of Alzheimer's disease via regulating the ubiquitination-mediated degradation of APP.
Zhang J, Liu C, Liu J, Cui Y, Hou Y, Song Q, Zhang X, Wang X, Zhang Q, Cao M, Wang W, Wang P, Wang Y
Alzheimer's research & therapy 2025 Apr 29;17(1):95
Alzheimer's research & therapy 2025 Apr 29;17(1):95
Genome-wide CRISPR screening identifies LRP1 as an entry factor for SFTSV.
Xing C, Zhang C, Xu Z, Wang Y, Lu W, Liu X, Zhang Y, Ma J, Yang S, Du Y, Xu G, Liu Y
Nature communications 2025 Apr 29;16(1):4036
Nature communications 2025 Apr 29;16(1):4036
PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1.
Dai W, Yu Q, Ma R, Zheng Z, Hong L, Qi Y, He F, Wang M, Ge F, Yu X, Li S
Nature communications 2025 Apr 29;16(1):4030
Nature communications 2025 Apr 29;16(1):4030
Baicalin Relieves Glaesserella parasuis-Triggered Immunosuppression Through Polarization via MIF/CD74 Signaling Pathway in Piglets.
Fu S, Dong Q, Fu Y, Luo R, Li J, Sun Y, Liu S, Qiu Y, Guo L, Hu J
Biomolecules 2025 Apr 29;15(5)
Biomolecules 2025 Apr 29;15(5)
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER-phagy pathway.
Zheng X, Fang D, Shan H, Xiao B, Wei D, Ouyang Y, Huo L, Zhang Z, Wu Y, Zhang R, Kang T, Gao Y
Cell discovery 2025 Apr 29;11(1):41
Cell discovery 2025 Apr 29;11(1):41
HMOX1 as a Novel Biomarker for Glucose-Lipid Metabolism Disorder and T2DM: Systematic Bioinformatics Investigation and Experimental Verification.
Xu Q, Zhang H, Ruan N, Jing J, Li Y, Zhao J, Fang Z
ACS omega 2025 Apr 29;10(16):16123-16137
ACS omega 2025 Apr 29;10(16):16123-16137
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
Wang C, Su Y, Shi J, Feng G
Journal of molecular histology 2025 Apr 28;56(3):146
Journal of molecular histology 2025 Apr 28;56(3):146
Transcranial Magnetic Stimulation Alleviates Spatial Learning and Memory Impairment by Inhibiting the Expression of SARM1 in Rats with Cerebral Ischemia-Reperfusion Injury.
Jiang L, Wang Y, He Y, Wang Y, Liu H, Chen Y, Ma J, Yin Y, Niu L
Neuromolecular medicine 2025 Apr 28;27(1):31
Neuromolecular medicine 2025 Apr 28;27(1):31
Granulosa cell RNA-Seq insights into senescence and sphingolipid metabolism disorder in PCOS: aspirin as a potential therapeutic drug.
Shi W, Lin H, Di W, He C, Shen Y
Reproductive biology and endocrinology : RB&E 2025 Apr 26;23(1):61
Reproductive biology and endocrinology : RB&E 2025 Apr 26;23(1):61
A compound heterozygous mutation in ZP1 and two novel heterozygous cis mutations in ZP3 causes infertility in women presenting with empty follicle syndrome.
Wang X, Liu Y, Yuan G, Yang J, Liu X, Chen S, Dou H, Lu P, Han L, Li D, Hao C
Journal of ovarian research 2025 Apr 26;18(1):86
Journal of ovarian research 2025 Apr 26;18(1):86
MMP1-induced NF-κB activation promotes epithelial-mesenchymal transition and sacituzumab govitecan resistance in hormone receptor-positive breast cancer.
Chen L, Cen Y, Qian K, Yang W, Zhou W, Yang Y
Cell death & disease 2025 Apr 26;16(1):346
Cell death & disease 2025 Apr 26;16(1):346
RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria.
Behera AK, Kim JJ, Kordale S, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Gonatopoulos-Pournatzis T
bioRxiv : the preprint server for biology 2025 Apr 26;
bioRxiv : the preprint server for biology 2025 Apr 26;
Dendrobine alleviates LPS-induced acute lung injury via activation of the PI3K/AKT/GSK3β pathway.
Zhou J, Li S, Zeng Z
Journal of ethnopharmacology 2025 Apr 25;346:119634
Journal of ethnopharmacology 2025 Apr 25;346:119634
Development of a Long-Acting Interleukin-11 Antagonist for the Treatment of Renal Fibrosis.
Pang N, Zhao N, An C, Li K, Li P, Wang N, Li J, Cheng X, Zheng N, Guo D, Xiong X
Journal of medicinal chemistry 2025 Apr 24;68(8):8429-8438
Journal of medicinal chemistry 2025 Apr 24;68(8):8429-8438
Discovery of Novel SHP2 ATTEC Degraders against Pancreatic Ductal Adenocarcinoma Harboring KRAS(G12D) Mutations.
Zhong Y, Lu Y, Li J, Ren Q, Fan Y, Meng X, Shao J, Qian H
Journal of medicinal chemistry 2025 Apr 24;68(8):8143-8162
Journal of medicinal chemistry 2025 Apr 24;68(8):8143-8162
Kanglexin attenuates spinal cord injury by modulating pyroptosis and polarization via the PKA/NF-κB signaling pathway.
Yan R, Yuan Y, Shi C, Li Y, Li Y, Wang W, Yang L
International immunopharmacology 2025 Apr 24;153:114401
International immunopharmacology 2025 Apr 24;153:114401
Apigenin-Mediated ESCRT-III Activation and Mitophagy Alleviate LPS-Induced Necroptosis in Renal Cells.
Guo J, Hu JP, Liu M, Chen Y, Zhang S, Guan S
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9906-9919
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9906-9919
Neutrophil extracellular traps induced by neoadjuvant chemotherapy of breast cancer promotes vascular endothelial damage.
Kong L, Hu S, Zhao Y, Huang Y, Xiang X, Yu Y, Mao X, Xie K, Zhu X, Xu P
Breast cancer research : BCR 2025 Apr 23;27(1):61
Breast cancer research : BCR 2025 Apr 23;27(1):61
Lactiplantibacillus plantarum -derived extracellular vesicles alleviate acute lung injury by inhibiting ferroptosis of macrophages.
Zhao Q, Lai J, Jiang Y, Cui E, Chang H, Pan R, Li P, Shao JZ, Zheng J, Chen Y
Journal of nanobiotechnology 2025 Apr 23;23(1):307
Journal of nanobiotechnology 2025 Apr 23;23(1):307
Intranasal Transplantation of Microbiota Derived from Parkinson's Disease Mice Induced Astrocyte Activation and Neurodegenerative Pathology from Nose to Brain.
Xia YM, Zhang MX, Ma XY, Tan LL, Li T, Wu J, Li MA, Zhao WJ, Qiao CM, Jia XB, Shen YQ, Cui C
Brain sciences 2025 Apr 23;15(5)
Brain sciences 2025 Apr 23;15(5)
Mitophagy Protects Against Cisplatin-Induced Injury in Granulosa Cells.
Zhu S, Tang M, Chen J, Li S, Xue R
Toxics 2025 Apr 23;13(5)
Toxics 2025 Apr 23;13(5)
Comprehensive PTM profiling with SCASP-PTM uncovers mechanisms of p62 degradation and ALDOA-mediated tumor progression.
Lin ZP, Gan G, Xu X, Wen C, Ding X, Chen XY, Zhang K, Guo WY, Lin M, Wang YY, Chen X, Xie C, Wang J, Li M, Zhong CQ
Cell reports 2025 Apr 22;44(4):115500
Cell reports 2025 Apr 22;44(4):115500
LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia.
Zhang Y, Wu H, Zhang Q, Cong P, Li Z, Wu Q, Huang X, Li X, Feng B, Liu Q, Xiong L
Cell reports 2025 Apr 22;44(4):115489
Cell reports 2025 Apr 22;44(4):115489
Identification of a novel tRNA-derived small RNA fragment, tRF-16-2YU04DE, with the potential of inhibiting endometrial cancer progression.
Hu H, Wu Y, Yuan S, Li H, Xiao S, Liu J, Li Y, Xie X, Gong Z, Zhong S, Xu H
Medical oncology (Northwood, London, England) 2025 Apr 22;42(5):173
Medical oncology (Northwood, London, England) 2025 Apr 22;42(5):173
Identifying PSIP1 as a critical R-loop regulator in osteosarcoma via machine-learning and multi-omics analysis.
Nie J, Wang S, Zhong Y, Yang F, Liu J, Liu Z
Cancer cell international 2025 Apr 22;25(1):159
Cancer cell international 2025 Apr 22;25(1):159
Hydrogel-Based Bioactive Synthetic Skin Stimulates Regenerative Gas Signaling and Eliminates Interfacial Pathogens to Promote Burn Wound Healing.
Zhang H, Zhou W, Wang H, Zhang J, Yang H, Chen J, Wang S, Zhao W, Li M, Luo Z
ACS nano 2025 Apr 22;19(15):15002-15017
ACS nano 2025 Apr 22;19(15):15002-15017
Remodeling of Effector and Regulatory T Cells by Capture and Utilization of miRNAs Using Nanocomposite Hydrogel for Tumor-Specific Photothermal Immunotherapy.
Chen L, Zhu M, Zhang H, Tang W, Liu J, Tang X, Chang X, Zhu Z, Liu T, Weng L, Zhang Y, Chen X
ACS nano 2025 Apr 22;19(15):14873-14892
ACS nano 2025 Apr 22;19(15):14873-14892
Periostin-mediated activation of NF-κB signaling promotes tumor progression and chemoresistance in glioblastoma.
Shang Y, Liang Y, Zhang B, Wu W, Peng Y, Wang J, Zhang M, Niu C
Scientific reports 2025 Apr 22;15(1):13955
Scientific reports 2025 Apr 22;15(1):13955
Curcumin prevents dexamethasone-induced activation of the pseudorabies virus in rat pheochromocytoma cells through the miR-155-5p-Aak1-Numb/Notch2 signalling axis.
Wang N, Yang F, Qiu Z, Zhang L, Zou D, Tang Y, Zhang R, Sun C, Liu P, Qi K, Wang J, He H, Gan L
Veterinary research 2025 Apr 21;56(1):86
Veterinary research 2025 Apr 21;56(1):86
RNA Methylation and Transcriptome Analysis Reveal Key Regulatory Pathways Related to Cadmium-Induced Liver Damage.
Huang H, Li G, Guo S, Li K, Li W, Zhou Q, He Z, Yang X, Liu L, Wei Q
Chemical research in toxicology 2025 Apr 21;38(4):717-732
Chemical research in toxicology 2025 Apr 21;38(4):717-732
Calpain inhibition as a novel therapeutic strategy for aortic dissection with acute lower extremity ischemia.
Tan Q, Wang X, Xu W, Song K, Xiong Y, Jiang Z, Li J, Yu Y, Ye W, Shen Z, Teng X
Molecular medicine (Cambridge, Mass.) 2025 Apr 21;31(1):144
Molecular medicine (Cambridge, Mass.) 2025 Apr 21;31(1):144
Emodin alleviates the damage to lens epithelial cells in diabetic cataract by repressing the p53-mediated ferroptosis pathway.
Zuo X, Wang X, Xie J, Jia Y
International ophthalmology 2025 Apr 2;45(1):141
International ophthalmology 2025 Apr 2;45(1):141
Ribosome profiling reveals that post-transcriptional control of Nalf1 by heterogeneous nuclear ribonucleoprotein L is required for paclitaxel-induced neuropathic pain.
de la Peña JB, García G, Campbell ZT
Pain 2025 Apr 2;166(9):2091-2102
Pain 2025 Apr 2;166(9):2091-2102
Faecalibacterium prausnitzii-derived outer membrane vesicles reprogram gut microbiota metabolism to alleviate Porcine Epidemic Diarrhea Virus infection.
Xing J, Niu T, Yu T, Zou B, Shi C, Wang Y, Fan S, Li M, Bao M, Sun Y, Gao K, Qiu J, Zhang D, Wang N, Jiang Y, Huang H, Cao X, Zeng Y, Wang J, Zhang S, Hu J, Zhang D, Sun W, Yang G, Yang W, Wang C
Microbiome 2025 Apr 2;13(1):90
Microbiome 2025 Apr 2;13(1):90
HPV16 E7 inhibits HBD2 expression by down-regulation of ASK1-p38 MAPK pathway in cervical cancer.
Liao J, Deng S, Shi B, Wang M, Yin Y, Cao Y, Liu R, Huang X, Jiang L, Shi Q
Virology journal 2025 Apr 19;22(1):109
Virology journal 2025 Apr 19;22(1):109
MC-LR induced apoptosis in human embryonic kidney (HEK293) cells through activation of TNF-R1/RIPK1 pathway.
Wang Y, Yang Y, Yuan M, Yang F, Zeng W, Liu J, Zhan C
Journal of toxicology and environmental health. Part A 2025 Apr 18;88(8):339-348
Journal of toxicology and environmental health. Part A 2025 Apr 18;88(8):339-348
Co-Highly Expressed SLC17A9 and KCNH1 as Potential Prognostic Biomarkers and Therapeutic Targets in Clear Cell Renal Cell Carcinoma.
Ke Z, Tang Z, Shen D, Liu Y, Shu Y, Mu X, Li Z, Xiang P, Zhong B, Hu X, Tan R, Xiao J
Frontiers in bioscience (Landmark edition) 2025 Apr 18;30(4):38061
Frontiers in bioscience (Landmark edition) 2025 Apr 18;30(4):38061
The m6A methyltransferase METTL3 affects ferroptosis in non-small cell lung cancer by regulating the PTEN/PI3K/AKT pathway.
Wu B, Li D, Wang Y, Pan T, Xu J, Li L
Discover oncology 2025 Apr 18;16(1):559
Discover oncology 2025 Apr 18;16(1):559
Nobiletin Enhances Skeletal Muscle Mass and Modulates Bile Acid Composition in Diet-Induced Obese Mice.
Koh YC, Liu CP, Leung SY, Lin WS, Ho PY, Ho CT, Pan MH
Journal of agricultural and food chemistry 2025 Apr 16;73(15):9076-9087
Journal of agricultural and food chemistry 2025 Apr 16;73(15):9076-9087
Condensation of cellular prion protein promotes renal fibrosis through the TBK1-IRF3 signaling axis.
Long T, Lu Y, Ma Y, Song Y, Yi X, Chen X, Zhou M, Ma J, Chen J, Liu Z, Zhu F, Hu Z, Zhou Z, Li C, Hou FF, Zhang L, Chen Y, Nie J
Science translational medicine 2025 Apr 16;17(794):eadj9095
Science translational medicine 2025 Apr 16;17(794):eadj9095
Synthesis of AgInS(2) quantum dots loaded with celastrol for induction of apoptosis and autophagy in hepatocellular carcinoma cells.
Gong Q, Zhu T, Zhang L, Wu H, Miao Y, Hu Y
Discover oncology 2025 Apr 16;16(1):538
Discover oncology 2025 Apr 16;16(1):538
Activation of the hippocampal CA1 astrocyte Gq and Gi G protein-coupled receptors exerts a protective effect against attention deficit hyperactivity disorder.
Shan YD, Yu ZF, Lv GG, Shan YL, Li BD, Zhao JY, Li XM, Gao WJ, Zhang LM
International immunopharmacology 2025 Apr 16;152:114382
International immunopharmacology 2025 Apr 16;152:114382
The African swine fever virus MGF360-16R protein functions as a mitochondrial-dependent apoptosis inducer by competing with BAX to bind to the HSP60 protein.
Xiang Z, Xu Z, Weng W, Wang H, Wu J, Jiang F, Qu Y, Li Q, Gao P, Zhou L, Ge X, Guo X, Han J, Zhang Y, Yang H
Journal of virology 2025 Apr 15;99(4):e0140124
Journal of virology 2025 Apr 15;99(4):e0140124
Human long noncoding RNA VILMIR is induced by major respiratory viral infections and modulates the host interferon response.
John K, Huntress I, Smith E, Chou H, Tollison TS, Covarrubias S, Crisci E, Carpenter S, Peng X
Journal of virology 2025 Apr 15;99(4):e0014125
Journal of virology 2025 Apr 15;99(4):e0014125
Integrative analysis of bulk RNA and single-cell sequencing data reveals a liquid-liquid phase separation signature for clear cell renal cell carcinoma.
Wang H, Liu Z, Zhang L, Cheng X, Du Y, Guo Y, Zhang Z, Gao Y, Shang P
Gene 2025 Apr 15;945:149313
Gene 2025 Apr 15;945:149313
lncRNA NR_146969 promotes the progression of lung adenocarcinoma.
Chen Y, Wang J, Gu L, Chen H, Gai Z, Hu R, Qing B, Yuan Y, Xia Z
Experimental cell research 2025 Apr 15;447(2):114535
Experimental cell research 2025 Apr 15;447(2):114535
3,4-Dimethoxychalcone alleviates limb ischemia/reperfusion injury by TFEB-mediated autophagy enhancement and antioxidative response.
Qiu YH, Zhang YH, Wu ZC, Huang JY, Chen BC, Xiao J, Chen FF
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70496
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70496
Discovery of novel sitolactone derivative leading to PANoptosis and differentiation of acute myeloid leukemia cells.
Wang J, Wang N, Wang M, Liu N, Wang C, Li N, Mu L, Jiang Y, Chen J, Li J, Yang G, Wang J, Liu S, Zhang K
European journal of medicinal chemistry 2025 Apr 15;288:117360
European journal of medicinal chemistry 2025 Apr 15;288:117360
Cold atmospheric plasma drives USP49/HDAC3 axis mediated ferroptosis as a novel therapeutic strategy in endometrial cancer via reinforcing lactylation dependent p53 expression.
Liu J, Li Y, Ma R, Chen Y, Wang J, Zhang L, Wang B, Zhang Z, Huang L, Zhang H, Wan J, Liu H
Journal of translational medicine 2025 Apr 15;23(1):442
Journal of translational medicine 2025 Apr 15;23(1):442
Synchronously Evoking Disulfidptosis and Ferroptosis via Systematical Glucose Deprivation Targeting SLC7A11/GSH/GPX4 Antioxidant Axis.
Zhang M, Zheng H, Zhu X, Liu S, Jin H, Chen Y, Wan L, Zhang S, Zhang H
ACS nano 2025 Apr 15;19(14):14233-14248
ACS nano 2025 Apr 15;19(14):14233-14248
CCN1 is a therapeutic target upregulated in EML4-ALK mutant lung adenocarcinoma reversibly resistant to alectinib.
Huang Y, Huang J, Zhan J, Chen M, Zheng J, He J, Fang W, Zhang L, Li J
Cell death & disease 2025 Apr 15;16(1):303
Cell death & disease 2025 Apr 15;16(1):303
The dual HDAC/PI3K inhibitor CUDC-907 inhibits the growth and proliferation of MYC-driven Group 3 medulloblastoma.
Gou P, Fang C, Xu M, Zhang D, Wu X, Zhang L, Li X, Li M, Gan L, Luo J, Cui H, Liang P
Cell death discovery 2025 Apr 14;11(1):172
Cell death discovery 2025 Apr 14;11(1):172
RFX5 promotes the progression of triple-negative breast cancer through transcriptional activation of JAG1.
Li C, Wang X, Shi D, Yang M, Yang W, Chen L
Human cell 2025 Apr 12;38(3):86
Human cell 2025 Apr 12;38(3):86
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
He J, Yue H, Zhang S, Dong R, Zhang F, Wang X, Wang K, Zhang H, Yang D, Dong Z, Liu H
Respiratory research 2025 Apr 12;26(1):136
Respiratory research 2025 Apr 12;26(1):136
Mechanistic evaluation of Jiu Wei Qing Zhi Gao in non-alcoholic fatty liver disease: insights from network Pharmacology and experimental validation.
Chen Q, Hu Q, Zhang F, Lu W, Yuan Z, Qiao F
Hereditas 2025 Apr 12;162(1):59
Hereditas 2025 Apr 12;162(1):59
Therapeutic potential of naturally derived carbon dots in sepsis-associated acute kidney injury.
Wang L, Li ZY, Zhong CL, Teng ZY, Wang B, Rehman A, Han LW, Zeng KW, Zhang JG, Lu ZY
Chinese medicine 2025 Apr 11;20(1):49
Chinese medicine 2025 Apr 11;20(1):49
Covariation of scleral remodeling and PI3K/Akt signaling pathway in experimental myopia.
Li X, Liu X, Yu Y, Li T, Guo L, Hu G, Wei H, Yang Z, Liu J, Hao Y, Zhang R, Wu Q, Liao X, Guo D, Bi H
Scientific reports 2025 Apr 11;15(1):12476
Scientific reports 2025 Apr 11;15(1):12476
METTL3 Plays Regulatory Roles in Acute Pneumonia during Staphylococcus aureus Infection.
Wu M, Nie Q, Zhang Y, Qin J, Ye L, Zhao R, Dai M, Wu M
ACS infectious diseases 2025 Apr 11;11(4):905-916
ACS infectious diseases 2025 Apr 11;11(4):905-916
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Macrophage membrane enveloped on double-locked nanoplatform with right-side-out orientation to improving precise theranostic for atherosclerosis.
Liu J, He Z, Qin X, Zhang K, Qu K, Zhong Y, Yang W, Wu W
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:800-817
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:800-817
EBV enhances immunotherapy sensitivity in intrahepatic cholangiocarcinoma through cGAS-STING pathway activation.
Huang L, Zhong Q, Huang S, Yang K, Cai Y, Guo G
Hepatology communications 2025 Apr 1;9(4)
Hepatology communications 2025 Apr 1;9(4)
Oxypeucedanin alleviates cisplatin-induced intestinal toxicity through impairing caspase-3/gasdermin E signaling.
Wang R, Gao F, Hao L, Zhang J, Chen Z, Song D, Gao F, He W, Zhao K, Guan J
The Journal of veterinary medical science 2025 Apr 1;87(4):431-441
The Journal of veterinary medical science 2025 Apr 1;87(4):431-441
Rnd3 Ameliorates Diabetic Cardiac Microvascular Injury via Facilitating Trim40-Mediated Rock1 Ubiquitination.
Lin J, Zhang X, Ge W, Duan Y, Zhang X, Zhang Y, Dai X, Jiang M, Zhang X, Zhang J, Qiang H, Sun D
Diabetes 2025 Apr 1;74(4):569-584
Diabetes 2025 Apr 1;74(4):569-584
AZGP1 Attenuates Subretinal Fibrosis and Inhibits Epithelial-Mesenchymal Transition by Blocking the PI3K/AKT Signaling Pathway.
Yang Y, Shen J, Li Y, Chen X, Liu G, Lu P
Investigative ophthalmology & visual science 2025 Apr 1;66(4):83
Investigative ophthalmology & visual science 2025 Apr 1;66(4):83
Tumor-derived miR-203a-3p potentiates muscle wasting by inducing muscle ferroptosis in pancreatic cancer.
Hu Y, Hu Y, Zhang S, Guo Y, Wang F, Du Y, Wang L, Li P, Xu Y, Zhang H, Yang Z, Liu Z, Xu J, Liu M
Cancer letters 2025 Apr 1;614:217523
Cancer letters 2025 Apr 1;614:217523
Hesperidin produces antidepressant effects by activating AMPA receptor: enhancing synaptic proteins to promote hippocampal neuronal activities.
Pang B, Cao T
Behavioural pharmacology 2025 Apr 1;36(2-3):127-136
Behavioural pharmacology 2025 Apr 1;36(2-3):127-136
The TEAD4-DYNLL1 axis accelerates cell cycle progression and augments malignant properties of lung adenocarcinoma cells.
Li D, Wang A, Wang X, Shi M, Chen X, Lyu Y, Huang D
European journal of medical research 2025 Apr 1;30(1):221
European journal of medical research 2025 Apr 1;30(1):221
Ultrasmall Bi@Au Schottky Heterojunction with a High Potential Barrier for Amplifying Radioimmunotherapy.
Shen C, Niu X, Zhang J, Wang S, Chen J, Xu F, Duan Y, Zhang Y, Weng L, Luo Z, Wang L
ACS nano 2025 Apr 1;19(12):12382-12398
ACS nano 2025 Apr 1;19(12):12382-12398
DNA Methylation Mediates the Transcription of STAT4 to Regulate KISS1 During Follicular Development.
Chen D, Fang M, Huang E, Quan H, Zhang L, He Y, Zhou X, Ma B, Yuan X, Li J
Cells 2025 Apr 1;14(7)
Cells 2025 Apr 1;14(7)
TLR4/Rac1/NLRP3 Pathway Mediates Amyloid-β-Induced Neuroinflammation in Alzheimer's Disease.
Zhu M, Liu Y, Chen C, Chen H, Ni W, Song Y, Lv B, Hua F, Cui G, Zhang Z
Journal of Alzheimer's disease : JAD 2024;99(3):911-925
Journal of Alzheimer's disease : JAD 2024;99(3):911-925
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Chen X, Wang J, Tu F, Yang Q, Wang D, Zhu Q
Ginekologia polska 2024;95(9):661-667
Ginekologia polska 2024;95(9):661-667
Impact and mechanisms of drag-reducing polymers on shear stress regulation in pulmonary hypertension.
Wang Y, Ye Q, Cui Y, Wu Y, Cao S, Hu F
Clinical hemorheology and microcirculation 2024;88(2):247-261
Clinical hemorheology and microcirculation 2024;88(2):247-261
Glucosamine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress and inflammation.
Lai W, Zhou S, Bai Y, Che Q, Cao H, Guo J, Su Z
Current research in food science 2024;8:100699
Current research in food science 2024;8:100699
Effects of Different Light Environments with Varying Spectral Composition on the Axial Lengths and Scleral Specificity Protein 1 and Collagen Type I Expression in Juvenile Guinea Pigs.
Yuan J, Wang Y, Xu X, Yang M, Fan Y, Shi X, Sun L, Shan M, Ma L
Folia biologica 2024;70(4):219-228
Folia biologica 2024;70(4):219-228
Taurine Improved Autism-Like Behaviours and Defective Neurogenesis of the Hippocampus in BTBR Mice through the PTEN/mTOR/AKT Signalling Pathway.
Xiaoyan H, Zhaoxi Y, Lingli Z, Jinyuan C, Wen Q
Folia biologica 2024;70(1):45-52
Folia biologica 2024;70(1):45-52
Chronic Ethanol Intake Impairs Niacin Nutritional Status in Mice.
Mizutani A, Goto C, Fujigaki H, Yamamoto Y, Saito K, Hatayama S, Fukuwatari T
Journal of nutritional science and vitaminology 2024;70(1):1-8
Journal of nutritional science and vitaminology 2024;70(1):1-8
Cytotoxicity and inhibitory potential of CUDC-101 in non-small cell lung cancer cells with rare EGFR L861Q mutation.
Chu C, Xu H, Liu C, Wei X, Li L, Wang R, Cui W, Zhang G, Liu C, Wang K, An L, He F
Current research in toxicology 2024;7:100194
Current research in toxicology 2024;7:100194
Diacylglycerol O-acyltransferase 2, a Novel Target of Flavivirus NS2B3 Protease, Promotes Zika Virus Replication by Regulating Lipid Droplet Formation.
Luo X, Yuan Y, Ma X, Luo X, Chen J, Chen C, Yang X, Yang J, Zhu X, Li M, Liu Y, Zhang P, Liu C
Research (Washington, D.C.) 2024;7:0511
Research (Washington, D.C.) 2024;7:0511
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis.
Zhu P, Wu Z, Yang Z, Tang T, Liao Y, Zhao W, Huang Y, Chen T, Li J, Nong C, Wu Z, Hu G, Liu Y, Chen Y
Research (Washington, D.C.) 2024;7:0344
Research (Washington, D.C.) 2024;7:0344
Opioid growth factor receptor overexpression exerts anti-hepatocellular carcinoma effects by activating P16 and P21 to inhibit proliferation and migration of HepG2 cells.
Jin Z, Jin Y
Folia histochemica et cytobiologica 2024;62(4):180-190
Folia histochemica et cytobiologica 2024;62(4):180-190
The duration-dependent and sex-specific effects of neonatal sevoflurane exposure on cognitive function in rats.
Cheng J, Wang Z, Yu H, Chen Y, Wang Z, Zhang L, Peng X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13437
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13437
Isoliquiritigenin Suppresses Breast Tumor Development by Enhancing Host Antitumor Immunity.
Yuan CL, Yang XL, Sun L, Jiang YX, Zhang DD, Huang S
The American journal of Chinese medicine 2024;52(6):1819-1841
The American journal of Chinese medicine 2024;52(6):1819-1841
Exploring the impact of insufficient thermal ablation on hepatocellular carcinoma: NDST2 overexpression mechanism and its role in facilitating growth and invasion of residual cancer cells.
Wan W, Guo D, Kang T, Pang J, Pan Y, Chen J, Liao W, Chen Y, Lin P, Li L, Yang H, He Y
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2024;41(1):2353309
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2024;41(1):2353309
The Epstein-Barr virus-miRNA-BART6-5p regulates TGF-β/SMAD4 pathway to induce glycolysis and enhance proliferation and metastasis of gastric cancer cells.
Zhao X, Huang X, Dang C, Wang X, Qi Y, Li H
Oncology research 2024;32(5):999-1009
Oncology research 2024;32(5):999-1009
MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1.
Wang M, Li W, Han G, Bai X, Xie J
Protein and peptide letters 2024;31(7):559-568
Protein and peptide letters 2024;31(7):559-568
Development and Validation of the Diagnostic Model of 7 Gene in Endometriosis.
Zhu R, Liu Y, Zhou J, Lv Z, Shi K, Xiong J
Current medicinal chemistry 2024;31(41):6871-6888
Current medicinal chemistry 2024;31(41):6871-6888
Network Pharmacology and In vitro Experimental Verification to Explore the Mechanism of Chaiqin Qingning Capsule in the Treatment of Pain.
Gao H, Chen Z, Halihaman B, Huang L, Wang Z, Ding X
Current pharmaceutical design 2024;30(4):278-294
Current pharmaceutical design 2024;30(4):278-294
The generation and characterization of a transgenic zebrafish line with lens-specific Cre expression.
Peng X, Jia X, Shang G, Xue M, Jiang M, Chen D, Zhang F, Hu Y
Molecular vision 2024;30:123-136
Molecular vision 2024;30:123-136
Customized Sized Manganese Sulfide Nanospheres as Efficient T(1) MRI Contrast Agents for Enhanced Tumor Theranostics.
Gong Y, Guo K, Cai S, Ren K, Tian L, Wang Y, Mu M, Meng Q, Liu J, Sun X
Biomaterials research 2024;28:0116
Biomaterials research 2024;28:0116
CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial Homeostasis.
Tu P, Pan Y, Wang L, Li B, Sun X, Liang Z, Liu M, Zhao Z, Wu C, Wang J, Wang Z, Song Y, Zhang Y, Ma Y, Guo Y
Biomaterials research 2024;28:0006
Biomaterials research 2024;28:0006
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation.
Shao L, Wang N, Yan Y, Tan Y, Wu Q, Lei L, Wang M, Liu L
Iranian journal of basic medical sciences 2024;27(6):685-694
Iranian journal of basic medical sciences 2024;27(6):685-694
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
Liu X, Zhao W, Hu M, Zhang Y, Wang J, Zhang L
Iranian journal of basic medical sciences 2024;27(5):588-595
Iranian journal of basic medical sciences 2024;27(5):588-595
Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma.
Huang X, Zhou L, Chen J, Zhang S
Iranian journal of basic medical sciences 2024;27(2):157-164
Iranian journal of basic medical sciences 2024;27(2):157-164
The Mechanism of Action and Experimental Verification of Narenmandula in the Treatment of Postmenopausal Osteoporosis.
Xiao J, Yu Z, Han Q, Guo Y, Ye J, Lian H, Wang L, Ma Y, Liu M
Combinatorial chemistry & high throughput screening 2024;27(15):2249-2259
Combinatorial chemistry & high throughput screening 2024;27(15):2249-2259
Genetic Polymorphisms of rs9949644 in MAPK4 Are Associated with Clinical Response to Methotrexate in Patients with Psoriasis.
Fan Z, Huang Q, Zhang Z, Han L, Fang X, Yang K, Huang G, Zheng Z, Yawalkar N, Lin Y, Wang Z, Yan K
Dermatology (Basel, Switzerland) 2024;240(1):111-118
Dermatology (Basel, Switzerland) 2024;240(1):111-118
LRG1 promotes the apoptosis of pulmonary microvascular endothelial cells through KLK10 in chronic obstructive pulmonary disease.
Cheng W, Song Q, Zhou A, Lin L, Zhao Y, Duan J, Zhou Z, Peng Y, Liu C, Zeng Y, Chen P
Tobacco induced diseases 2024;22
Tobacco induced diseases 2024;22
Trans 10, cis 12-conjugated linoleic acid reduced reproductive ability by disrupting the estrus cycle in female mice.
Yu S, Wang B, Rao Y, Liu M, Liang L, Gou K
Animal reproduction 2024;21(2):e20240010
Animal reproduction 2024;21(2):e20240010
Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis.
Wu T, Liu S, Chen W, Zhao D, Lu Z
International journal of medical sciences 2024;21(2):319-331
International journal of medical sciences 2024;21(2):319-331
Chemically Modified PPARγ mRNA Unleashes Adipogenic Potential in 3T3-L1-Predipocytes: An Approach for Accelerated Wound Healing.
Luo Z, Lu Y, Zheng S, Liu K, Fu W, Pan Y
International journal of medical sciences 2024;21(13):2480-2493
International journal of medical sciences 2024;21(13):2480-2493
Matrix Metalloproteinase 11 Promotes Migration and Invasion of Colorectal Cancer by Elevating Slug Protein.
Pan C, Dai J, Wei Y, Yang L, Ding Z, Wang X, He J
International journal of medical sciences 2024;21(11):2170-2188
International journal of medical sciences 2024;21(11):2170-2188
Targeting the Ajuba/Notch axis increases the sensitivity of colon cancer cells to 5-fluorouracil.
Liang X, Liu X, Zhang L, Liu J, Yan R, Li H, Zeng X, Wang H
CytoJournal 2024;21:44
CytoJournal 2024;21:44
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin.
Zhang C, Wang WS, Yao G, Zhu Y, Lin Y, Lu J, Sun K, Sun Y
Human reproduction open 2024;2024(1):hoae002
Human reproduction open 2024;2024(1):hoae002
Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide-Induced Inflammatory Microenvironment through NLRP3 Inhibition.
Tang C, Guo X, Li Y, Yi Y, Tang Z, Zhang Q, Luo B, Chen K, Liang K, Li G
Mediators of inflammation 2024;2024:8828367
Mediators of inflammation 2024;2024:8828367
Identification and Verification of Hub Mitochondrial Dysfunction Genes in Osteoarthritis Based on Bioinformatics Analysis.
Niu H, Deng X, Zhang Q, Zhao Y, Wen J, Li W, Liu H, Guo X, Wu C
Journal of immunology research 2024;2024:6822664
Journal of immunology research 2024;2024:6822664
Conditioned Medium Derived From Human Dental Follicle Mesenchymal Stem Cells Alleviates Macrophage Proinflammatory Responses Through MAPK-ERK-EGR1 Axis.
Zhang C, Lv P, Liang Q, Zhou J, Wu B, Xu W
Stem cells international 2024;2024:5514771
Stem cells international 2024;2024:5514771
KIF26B and CREB3L1 Derived from Immunoscore Could Inhibit the Progression of Ovarian Cancer.
Cong S, Fu Y, Zhao X, Guo Q, Liang T, Wu D, Wang J, Zhang G
Journal of immunology research 2024;2024:4817924
Journal of immunology research 2024;2024:4817924
Shh Signaling from the Injured Lung Microenvironment Drives BMSCs Differentiation into Alveolar Type II Cells for Acute Lung Injury Treatment in Mice.
Wu M, Liu J, Zhang S, Jian Y, Guo L, Zhang H, Mi J, Qu G, Liu Y, Gao C, Cai Q, Wen D, Liu D, Sun J, Jiang J, Huang H
Stem cells international 2024;2024:1823163
Stem cells international 2024;2024:1823163
Construction of the miRNA/Pyroptosis-Related Molecular Regulatory Axis in Abdominal Aortic Aneurysm: Evidence From Transcriptome Data Combined With Multiple Machine Learning Approaches Followed by Experiment Validation.
Su Y, Lu C, Chen S
Journal of immunology research 2024;2024:1429510
Journal of immunology research 2024;2024:1429510
Genetically engineered macrophages derived from iPSCs for self-regulating delivery of anti-inflammatory biologic drugs.
Klimak M, Guilak F
Journal of tissue engineering and regenerative medicine 2024;2024
Journal of tissue engineering and regenerative medicine 2024;2024
Tumor-derived Exosomal ENO2 Modulates Polarization of Tumor-associated Macrophages through Reprogramming Glycolysis to Promote Progression of Diffuse Large B-cell Lymphoma.
Shao R, Liu C, Xue R, Deng X, Liu L, Song C, Xie J, Tang H, Liu W
International journal of biological sciences 2024;20(3):848-863
International journal of biological sciences 2024;20(3):848-863
BRD7 enhances the radiosensitivity of nasopharyngeal carcinoma cells by negatively regulating USP5/METTL3 axis-mediated homologous recombination repair.
Li M, Wei J, Xue C, Chen S, Zhou X, Zheng L, Duan Y, Deng H, Fan S, Xiong W, Tang F, Zhou M
International journal of biological sciences 2024;20(15):6130-6145
International journal of biological sciences 2024;20(15):6130-6145
NUSAP1 is Upregulated by Estrogen to Promote Lung Adenocarcinoma Growth and Serves as a Therapeutic Target.
Zhang S, Zhang X, Huang W, Jiang G, Mo Y, Wei L, Fan P, Chen M, Jiang W
International journal of biological sciences 2024;20(13):5375-5395
International journal of biological sciences 2024;20(13):5375-5395
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
Ji Q, Tu Z, Liu J, Zhou Z, Li F, Zhu X, Huang K
International journal of biological sciences 2024;20(11):4364-4381
International journal of biological sciences 2024;20(11):4364-4381
Combination of TrxR1 inhibitor and lenvatinib triggers ROS-dependent cell death in human lung cancer cells.
Zheng P, Xia Y, Shen X, Lu H, Chen Y, Xu C, Qiu C, Zhang Y, Zou P, Cui R, Huang X
International journal of biological sciences 2024;20(1):249-264
International journal of biological sciences 2024;20(1):249-264
Hypoxia-driven TNS4 fosters HNSCC tumorigenesis by stabilizing integrin α5β1 complex and triggering FAK-mediated Akt and TGFβ signaling pathways.
Zhao X, Mai Z, Liu L, Lu Y, Cui L, Yu J
International journal of biological sciences 2024;20(1):231-248
International journal of biological sciences 2024;20(1):231-248
Dual role of CD73 as a signaling molecule and adenosine-generating enzyme in colorectal cancer progression and immune evasion.
Lian W, Jiang D, Lin W, Jiang M, Zhang Y, Wang H, Zhao L
International journal of biological sciences 2024;20(1):137-151
International journal of biological sciences 2024;20(1):137-151
Wenyang-Tianjing-Jieyu Decoction Improves Depression Rats of Kidney Yang Deficiency Pattern by Regulating T Cell Homeostasis and Inflammation Level.
Zhang T, Wang J, Wang Y, He L, Lv S, Wang Y, Li W
Neuropsychiatric disease and treatment 2024;20:631-647
Neuropsychiatric disease and treatment 2024;20:631-647
High-dose radiation-induced immunogenic cell death of bladder cancer cells leads to dendritic cell activation.
Zeng X, Luo D, Zhang S, Cui Z, Wang Y, Chen J, Zhang S, Teng L, Hu Z, Liu L, Zhou S, Zeng Z, Long J
PloS one 2024;19(9):e0307024
PloS one 2024;19(9):e0307024
ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.
Tang D, Wang H, Jiang Y, Chen M, Zhang G, Wu S, Wang Y
PloS one 2024;19(12):e0316109
PloS one 2024;19(12):e0316109
HMGA2 as a prognostic and immune biomarker in hepatocellular carcinoma: Comprehensive analysis of the HMG family and experiments validation.
Zhong Q, Zhao B, She X, Liu X
PloS one 2024;19(11):e0311204
PloS one 2024;19(11):e0311204
Sepsis induces the cardiomyocyte apoptosis and cardiac dysfunction through activation of YAP1/Serpine1/caspase-3 pathway.
Long X, Yang Y, Zhou K
Open medicine (Warsaw, Poland) 2024;19(1):20241018
Open medicine (Warsaw, Poland) 2024;19(1):20241018
PEI/MMNs@LNA-542 nanoparticles alleviate ICU-acquired weakness through targeted autophagy inhibition and mitochondrial protection.
Wang Y, Xu Y, Zhao T, Ma YJ, Qin W, Hu WL
Open life sciences 2024;19(1):20220952
Open life sciences 2024;19(1):20220952
LARP1 knockdown inhibits cultured gastric carcinoma cell cycle progression and metastatic behavior.
Liu X, Zhang WM, Meng N, Lin LJ, Tang GD
Open life sciences 2024;19(1):20220806
Open life sciences 2024;19(1):20220806
Hybrid Liposome-MSN System with Co-Delivering Potential Effective Against Multidrug-Resistant Tumor Targets in Mice Model.
Yang Y, Yang S, Zhang B, Wang J, Meng D, Cui L, Zhang L
International journal of nanomedicine 2024;19:8949-8970
International journal of nanomedicine 2024;19:8949-8970
Development of an Intelligent Reactive Oxygen Species-Responsive Dual-Drug Delivery Nanoplatform for Enhanced Precise Therapy of Acute Lung Injury.
Xia D, Lu Z, Li S, Fang P, Yang C, He X, You Q, Sun G
International journal of nanomedicine 2024;19:2179-2197
International journal of nanomedicine 2024;19:2179-2197
Effective-Component Compatibility of Bufei Yishen Formula III Suppresses Mitochondrial Oxidative Damage in COPD: Via Pkm2/Nrf2 Pathway.
Liu Y, Zhang L, Zhao J, Lu R, Shao X, Xu K, Li J, Tian Y
International journal of chronic obstructive pulmonary disease 2024;19:1905-1920
International journal of chronic obstructive pulmonary disease 2024;19:1905-1920
SiRNF8 Delivered by DNA Framework Nucleic Acid Effectively Sensitizes Chemotherapy in Colon Cancer.
Guo Z, Song H, Tian Y, Xu J, Zhang G, Guo Y, Shen R, Wang D
International journal of nanomedicine 2024;19:171-188
International journal of nanomedicine 2024;19:171-188
Catalpol Enhances Osteogenic Differentiation of Human Periodontal Stem Cells and Modulates Periodontal Tissue Remodeling in an Orthodontic Tooth Movement Rat Model.
Hu J, Song Y, Zhang Y, Yang P, Chen S, Wu Z, Zhang J
Drug design, development and therapy 2024;18:4943-4960
Drug design, development and therapy 2024;18:4943-4960
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Zhou Y, Xiong X, Cheng Z, Chen Z, Wu S, Yu Y, Liu Y, Chen G, Li L
Drug design, development and therapy 2024;18:4825-4838
Drug design, development and therapy 2024;18:4825-4838
Chuanxiong Renshen Decoction Inhibits Alzheimer's Disease Neuroinflammation by Regulating PPARγ/NF-κB Pathway.
Hou J, Wang X, Zhang J, Shen Z, Li X, Yang Y
Drug design, development and therapy 2024;18:3209-3232
Drug design, development and therapy 2024;18:3209-3232
Morin Regulates M1/M2 Microglial Polarization via NF-κB p65 to Alleviate Vincristine-Induced Neuropathic Pain.
Shao Y, Chen Y, Lan X, Lu J, Tang G, Tang S, Zhai R, Chen C, Xiong X, Shi J
Drug design, development and therapy 2024;18:3143-3156
Drug design, development and therapy 2024;18:3143-3156
Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis.
Chen K, Yu Y, Wang Y, Zhu Y, Qin C, Xu J, Zou X, Tao T, Li Y, Jiang Y
Drug design, development and therapy 2024;18:259-275
Drug design, development and therapy 2024;18:259-275
Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer.
Chen S, Li M, Xue C, Zhou X, Wei J, Zheng L, Duan Y, Deng H, Tang F, Xiong W, Xiang B, Zhou M
Drug design, development and therapy 2024;18:1321-1338
Drug design, development and therapy 2024;18:1321-1338
N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-κB pathway in rats.
Zhao YZ, Zhang XN, Yin Y, Xiao PL, Gao M, Zhang LM, Zhou SH, Yu SN, Wang XL, Zhao YS
International journal of ophthalmology 2024;17(2):228-238
International journal of ophthalmology 2024;17(2):228-238
IRF2 Affects LPS- and IFN-γ-Induced Pro-Inflammatory Responses, Cell Viability, Migration and Apoptosis of Macrophages by Regulating IRG1.
Qin RX, Ma XY, Han ZY, Ma SY, Shen ZJ, Lu ZH, Sun Y, Yu WL
Journal of inflammation research 2024;17:9651-9664
Journal of inflammation research 2024;17:9651-9664
Comparison of the Cecum Ligation and Puncture Method and the Intraperitoneal Lipopolysaccharide Injection Method for the Construction of a New-Onset Atrial Fibrillation Model of Sepsis.
Ling X, Shen J, Liang J, Yang K, Yang J
Journal of inflammation research 2024;17:9103-9117
Journal of inflammation research 2024;17:9103-9117
Study on the Anti-Atherosclerotic Mechanisms of Xin-Tong-Tai Granule Through Network Pharmacology, Molecular Docking, and Experimental Validation.
Zhu J, Wang Z, Liu C, Shi M, Guo Z, Li Y, Yu R, Wei J
Journal of inflammation research 2024;17:8147-8164
Journal of inflammation research 2024;17:8147-8164
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
Dong J, Liu M, Bian Y, Zhang W, Yuan C, Wang D, Zhou Z, Li Y, Shi Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
NLRP3 Inflammasome Deficiency Alleviates Inflammation and Oxidative Stress by Promoting PINK1/Parkin-Mediated Mitophagy in Allergic Rhinitis Mice and Nasal Epithelial Cells.
Ding H, Lu X, Wang H, Chen W, Niu B
Journal of asthma and allergy 2024;17:717-731
Journal of asthma and allergy 2024;17:717-731
The AGEs/RAGE Signaling Pathway Regulates NLRP3-Mediated Neuronal Pyroptosis After MCAO Injury in Lepr(-/-) Obese Rats.
Zhao L, Li S, Wang X, Zhang L, Zhang J, Liu X, Hu Y, Xian X, Zhang F, Li W, Zhang M
Journal of inflammation research 2024;17:6935-6954
Journal of inflammation research 2024;17:6935-6954
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Guo C, Jiao M, Cui Y, Li P, Yao J, Dong J, Liao L
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Haploinsufficiency of Cnot3 Aggravates Acid-Induced Acute Lung Injury Likely Through Transcriptional and Post-Transcriptional Upregulation of Pro-Inflammatory Genes.
Yamaguchi T, Ozawa R, Minato T, Hoshizaki M, Kammura Y, Okawara K, Khalil YA, Nakamura M, Yamaura K, Fukuda M, Imai Y, Kuba K
Journal of inflammation research 2024;17:5415-5425
Journal of inflammation research 2024;17:5415-5425
Pretreatment with Indole-3-Propionic Acid Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction and Inflammation Through the AhR/NF-κB/NLRP3 Pathway.
Zhang Y, Li S, Fan X, Wu Y
Journal of inflammation research 2024;17:5293-5309
Journal of inflammation research 2024;17:5293-5309
Vitamin D Binding Protein: A Potential Factor in Geriatric COVID-19 Acute Lung Injury.
Jiang H, Chi X, Sun Y, Li H
Journal of inflammation research 2024;17:4419-4429
Journal of inflammation research 2024;17:4419-4429
FcγRIIb Exacerbates LPS-Induced Neuroinflammation by Binding with the Bridging Protein DAP12 and Promoting the Activation of PI3K/AKT Signaling Pathway in Microglia.
Han Y, Wang L, Ye X, Gong X, Shao X
Journal of inflammation research 2024;17:41-57
Journal of inflammation research 2024;17:41-57
New Insights into Roles of IL-7R Gene as a Therapeutic Target Following Intracerebral Hemorrhage.
Cui J, Wang H, Liu S, Zhao Y
Journal of inflammation research 2024;17:399-415
Journal of inflammation research 2024;17:399-415
Tuina Promotes Repair of Chronic Cervical Muscle Injury by Regulating Satellite Cell Proliferation and Differentiation and Inhibiting Myocyte Apoptosis.
Zhang J, Qu S, Huang Y, Zhang X, Tong X, Fang Y, Rao T, Liu K, Lin J, Lin Y, Zeng C, Zhang G, Jing X, Liao J, Kan Y
Journal of pain research 2024;17:3419-3429
Journal of pain research 2024;17:3419-3429
Every-other-day fasting inhibits pyroptosis while regulating bile acid metabolism and activating TGR5 signaling in spinal cord injury.
Song H, Pang R, Chen Z, Wang L, Hu X, Feng J, Wang W, Liu J, Zhang A
Frontiers in molecular neuroscience 2024;17:1466125
Frontiers in molecular neuroscience 2024;17:1466125
Identification and Validation of Genes Related to Macrophage Polarization and Cell Death Modes Under Mycobacterium tuberculosis Infection.
Yang Z, Wang J, Pi J, Hu D, Xu J, Zhao Y, Wang Y
Journal of inflammation research 2024;17:1397-1411
Journal of inflammation research 2024;17:1397-1411
Ubiquitination contributes to the regulation of GDP-mannose pyrophosphorylase B activity.
Franzka P, Mittag S, Chakraborty A, Huber O, Hübner CA
Frontiers in molecular neuroscience 2024;17:1375297
Frontiers in molecular neuroscience 2024;17:1375297
Knockdown of INPP5K compromises the differentiation of N2A cells.
Manzolillo A, Gresing L, Hübner CA, Franzka P
Frontiers in molecular neuroscience 2024;17:1356343
Frontiers in molecular neuroscience 2024;17:1356343
Downregulation of NAT1 Expression is Associated with Poor Prognosis and Immune Infiltration in COAD.
Xu H, Zhang H, Sun S, Zhang J, Huo J, Zhou C
Pharmacogenomics and personalized medicine 2024;17:133-148
Pharmacogenomics and personalized medicine 2024;17:133-148
Sodium Propionate Alleviates Atopic Dermatitis by Inhibiting Ferroptosis via Activation of LTBP2/FABP4 Signaling Pathway.
Xie A, Li W, Ye D, Yin Y, Wang R, Wang M, Yu R
Journal of inflammation research 2024;17:10047-10064
Journal of inflammation research 2024;17:10047-10064
Integrating network pharmacology with experimental validation to investigate the mechanism of Wuwei Zishen formula in improving perimenopausal syndrome.
Fu X, Wang H, Gai M, Dai Y, Chang J, Zhang H
American journal of translational research 2024;16(6):2190-2211
American journal of translational research 2024;16(6):2190-2211
Role of ferroptosis in Porphyromonas gingivalis-induced impairment of epithelial junction.
Shi X, Liu J, Lu Z, Li J, Zhang S, Li Q, Geng F, Pan Y
Journal of oral microbiology 2024;16(1):2334578
Journal of oral microbiology 2024;16(1):2334578
Expression Analysis of FANCD2 in Endometrial Carcinoma.
Zhang L, Chang J, Wu X
Cancer management and research 2024;16:1715-1725
Cancer management and research 2024;16:1715-1725
KYNU Expression Promotes Cisplatin Resistance in Esophageal Cancer.
Lu Y, Zhao X, Yuan M, Zhao M, Liu K, Zhang M, Qiu X, Yu X, Liu X, Wei D, Xie J, Cheng Z
Journal of Cancer 2024;15(9):2475-2485
Journal of Cancer 2024;15(9):2475-2485
Development and Validation of the novel Cuproptosis- and Immune-related Signature for Predicting Prognosis in Hepatocellular Carcinoma.
Zhang Y, Sui P, Zhong C, Liu J
Journal of Cancer 2024;15(8):2260-2275
Journal of Cancer 2024;15(8):2260-2275
Cuproptosis-related genes score and its hub gene GCSH: A novel predictor for cholangiocarcinomas prognosis based on RNA seq and experimental analyses.
He R, Li Y, Jiao P, Huang Y, Dong S, Mo L, Jiao X
Journal of Cancer 2024;15(6):1551-1567
Journal of Cancer 2024;15(6):1551-1567
Comprehensive analysis reveals TSPEAR as a prognostic biomarker in colorectal cancer.
Xue D, Peng H, Li Z, Xu J, Ma H, Dang Y, Li F, Wang G, Sun Q
Journal of Cancer 2024;15(3):809-824
Journal of Cancer 2024;15(3):809-824
Expression and role of FKBPL in lung adenocarcinoma.
She L, Zhang X, Shen R, He S, Miao X
Journal of Cancer 2024;15(1):166-175
Journal of Cancer 2024;15(1):166-175
ATP5J regulates microglial activation via mitochondrial dysfunction, exacerbating neuroinflammation in intracerebral hemorrhage.
Ren N, Zhang H, Li T, Ji H, Zhang Z, Wu H
Frontiers in immunology 2024;15:1509370
Frontiers in immunology 2024;15:1509370
Calycosin alleviates ferroptosis and attenuates doxorubicin-induced myocardial injury via the Nrf2/SLC7A11/GPX4 signaling pathway.
Han Q, Shi J, Yu Y, Yuan H, Guo Y, Liu X, Xue Y, Li Y
Frontiers in pharmacology 2024;15:1497733
Frontiers in pharmacology 2024;15:1497733
Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function.
Li B, Wang H, Wang M, Liang H, Hu T, Yang J, Li S, You X, Xia B, Yuan Y, Zou Y, Miao Y, Sun Y
Frontiers in microbiology 2024;15:1496280
Frontiers in microbiology 2024;15:1496280
Green carbon dots derived from Zingiberis Rhizoma Carbonisatum alleviate ovalbumin-induced allergic rhinitis.
Zhou L, Yang Y, Li T, Zhao Y, Yuan J, He C, Huang Y, Ma J, Zhang Y, Lu F, Wu J, Li Z, Kong H, Zhao Y, Qu H
Frontiers in immunology 2024;15:1492181
Frontiers in immunology 2024;15:1492181
Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.
Huang R, Chu D, Shi J, Xu R, Wang K
Frontiers in pharmacology 2024;15:1490759
Frontiers in pharmacology 2024;15:1490759
IRF7-deficient MDBK cell based on CRISPR/Cas9 technology for enhancing IBRV replication.
Ge G, Li D, Ling Q, Xu L, Ata EB, Wang X, Li K, Hao W, Gong Q, Li J, Shi K, Leng X, Du R
Frontiers in microbiology 2024;15:1483527
Frontiers in microbiology 2024;15:1483527
In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma.
Qian L, Xu Z, Luo T, Gao Z, Cheng K, He X, Zhang Z, Ren S, Zhu Y
Frontiers in immunology 2024;15:1482914
Frontiers in immunology 2024;15:1482914
Protective effects of small RNAs encapsulated in Artemisia Capillaris-derived exosomes against non-alcoholic fatty liver disease.
Xu M, Ma L, Liang H, Tang W, Gu S
Frontiers in pharmacology 2024;15:1476820
Frontiers in pharmacology 2024;15:1476820
Profiling hypoxia signaling reveals a lncRNA signature contributing to immunosuppression in high-grade glioma.
Li X, Xu J, Li X, Shi J, Wei C, Liang Q
Frontiers in immunology 2024;15:1471388
Frontiers in immunology 2024;15:1471388
Microglial adenosine A(2A) receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.
Cao Y, Wu Z, Zhang M, Ji R, Zhang H, Song L
Frontiers in pharmacology 2024;15:1467305
Frontiers in pharmacology 2024;15:1467305
Electroacupuncture may protect pulmonary dysplasia in offspring with perinatal nicotine exposure by altering maternal gut microbiota and metabolites.
Xie Y, Fang Y, Liu Y, Ji B, Sakurai R, Wang Y, Li H, Zhang L, Wu L, Guo T, Quan Y, Rehan VK
Frontiers in microbiology 2024;15:1465673
Frontiers in microbiology 2024;15:1465673
Spermidine attenuates chondrocyte inflammation and cellular pyroptosis through the AhR/NF-κB axis and the NLRP3/caspase-1/GSDMD pathway.
Guo X, Feng X, Yang Y, Zhang H, Bai L
Frontiers in immunology 2024;15:1462777
Frontiers in immunology 2024;15:1462777
KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.
Chen Y, Wu X, Jiang Z, Li X
Frontiers in pharmacology 2024;15:1461931
Frontiers in pharmacology 2024;15:1461931
Matrine regulates autophagy in ileal epithelial cells in a porcine circovirus type 2-infected murine model.
Wang H, Sun N, Sun P, Zhang H, Yin W, Zheng X, Fan K, Sun Y, Li H
Frontiers in microbiology 2024;15:1455049
Frontiers in microbiology 2024;15:1455049
Dexmedetomidine regulates the anti-oxidation and autophagy of adipose-derived stromal cells under H(2)O(2)-induced oxidative stress through Nrf2/p62 pathway and improves the retention rate of autologous fat transplantation.
Li Z, Wei Q, Li Y, Yang F, Ke C, Li T, Li L, Cai Z
Frontiers in pharmacology 2024;15:1453938
Frontiers in pharmacology 2024;15:1453938
Zhachong Shisanwei pill drug-containing serum protects H(2)O(2)-Induced PC12 cells injury by suppressing apoptosis, oxidative stress via regulating the MAPK signaling pathway.
Hu H, Sun Y, Yang Z, Che L, Cai M, Li X, Huang X, Bagen H, Qiqige W, Guleng W, Ma L, Tong H
Frontiers in pharmacology 2024;15:1445597
Frontiers in pharmacology 2024;15:1445597
APP-CD74 axis mediates endothelial cell-macrophage communication to promote kidney injury and fibrosis.
Liu B, Li F, Wang Y, Gao X, Li Y, Wang Y, Zhou H
Frontiers in pharmacology 2024;15:1437113
Frontiers in pharmacology 2024;15:1437113
The metabolomics changes in epididymal lumen fluid of CABS1 deficient male mice potentially contribute to sperm deformity.
Zhao X, Nie J, Zhou W, Zeng X, Sun X
Frontiers in endocrinology 2024;15:1432612
Frontiers in endocrinology 2024;15:1432612
Integrated bioinformatics analysis of nucleotide metabolism based molecular subtyping and biomarkers in lung adenocarcinoma.
Luo D, Wang H, Zeng Z, Chen J, Wang H
Frontiers in immunology 2024;15:1430171
Frontiers in immunology 2024;15:1430171
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia.
Xue C, Wang Y, Peng J, Feng S, Guan Y, Hao Y
Frontiers in pharmacology 2024;15:1429177
Frontiers in pharmacology 2024;15:1429177
Kumujan B suppresses TNF-α-induced inflammatory response and alleviates experimental colitis in mice.
Li X, Di Q, Li X, Zhao X, Wu H, Xiao Y, Tang H, Huang X, Chen J, Chen S, Gao Y, Gao J, Xiao W, Chen W
Frontiers in pharmacology 2024;15:1427340
Frontiers in pharmacology 2024;15:1427340
Multi-omics evaluation of the prognostic value and immune signature of FCN1 in pan-cancer and its relationship with proliferation and apoptosis in acute myeloid leukemia.
Zhong F, Song L, Li H, Liu J, Liu C, Guo Q, Liu W
Frontiers in genetics 2024;15:1425075
Frontiers in genetics 2024;15:1425075
Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD.
Lee HJ, Hwang JW, Kim J, Jo AR, Park JH, Jeong YJ, Jang JY, Kim SJ, Song JH, Hoe HS
Frontiers in immunology 2024;15:1421455
Frontiers in immunology 2024;15:1421455
Colquhounia root tablet improves diabetic kidney disease by regulating epithelial-mesenchymal transition via the PTEN/PI3K/AKT pathway.
Ma D, Zhang J, Du L, Shi J, Liu Z, Qin J, Chen X, Guo M
Frontiers in pharmacology 2024;15:1418588
Frontiers in pharmacology 2024;15:1418588
Conduction and validation of a novel mitotic spindle assembly related signature in hepatocellular carcinoma: prognostic prediction, tumor immune microenvironment and drug susceptibility.
Zhang Z, Zhang Y, Hu G, Wu Q, Zhou Y, Luo F
Frontiers in genetics 2024;15:1412303
Frontiers in genetics 2024;15:1412303
SNAP25-induced MYC upregulation promotes high-grade neuroendocrine lung carcinoma progression.
Chen Z, Wang S, Wang J, Wang Y, Qi X, An B, Sun L, Lin L
Frontiers in immunology 2024;15:1411114
Frontiers in immunology 2024;15:1411114
Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways.
Wang F, He G, Liu M, Sun Y, Ma S, Sun Z, Wang Y
Frontiers in pharmacology 2024;15:1410810
Frontiers in pharmacology 2024;15:1410810
Wogonin protects against bleomycin-induced mouse pulmonary fibrosis via the inhibition of CDK9/p53-mediated cell senescence.
Wang L, Lin F, Liu Y, Li W, Ding Q, Duan X, Yang L, Bai Z, Zhang M, Guo Y
Frontiers in pharmacology 2024;15:1407891
Frontiers in pharmacology 2024;15:1407891
Bacteroides fragilis capsular polysaccharide A ameliorates ulcerative colitis in rat by recovering intestinal barrier integrity and restoring gut microbiota.
Zhong Y, Chang X, Zhao Z, Zheng L, Kuang G, Li P, Liu C, Fan Y, Liang Z, Zhuang K, Xie Q, Liu Y
Frontiers in pharmacology 2024;15:1402465
Frontiers in pharmacology 2024;15:1402465
Unraveling the nexus of NAD+ metabolism and diabetic kidney disease: insights from murine models and human data.
Yang S, Gong W, Wang Y, Hao C, Guan Y
Frontiers in endocrinology 2024;15:1384953
Frontiers in endocrinology 2024;15:1384953
The oxidant-antioxidant imbalance was involved in the pathogenesis of chronic rhinosinusitis with nasal polyps.
Zhou J, Zhou J, Liu R, Liu Y, Meng J, Wen Q, Luo Y, Liu S, Li H, Ba L, Du J
Frontiers in immunology 2024;15:1380846
Frontiers in immunology 2024;15:1380846
The role of metabolic memory in diabetic kidney disease: identification of key genes and therapeutic targets.
Yang T, Feng Q, Shao M, Pan M, Guo F, Song Y, Huang F, Linlin Z, Wang J, Wu L, Qin G, Zhao Y
Frontiers in pharmacology 2024;15:1379821
Frontiers in pharmacology 2024;15:1379821
Development and verification of a manganese metabolism- and immune-related genes signature for prediction of prognosis and immune landscape in gastric cancer.
Han X, Leng C, Zhao S, Wang S, Chen S, Wang S, Zhang M, Li X, Lu Y, Wang B, Qi W
Frontiers in immunology 2024;15:1377472
Frontiers in immunology 2024;15:1377472
Anti-pulmonary fibrosis activity analysis of methyl rosmarinate obtained from Salvia castanea Diels f. tomentosa Stib. using a scalable process.
Ma L, Liu C, Zhao Y, Liu M, Liu Y, Zhang H, Yang S, An J, Tian Y, Cao Y, Qu G, Song S, Cao Q
Frontiers in pharmacology 2024;15:1374669
Frontiers in pharmacology 2024;15:1374669
Cell-type specific effects of mineralocorticoid receptor gene expression suggest intercellular communication regulating fibrosis in skeletal muscle disease.
Gomatam CK, Ingale P, Rodriguez G, Munger S, Pomeranets R, Krishna S, Lowe J, Howard ZM, Rafael-Fortney JA
Frontiers in physiology 2024;15:1322729
Frontiers in physiology 2024;15:1322729
Characterization of the m(6)A regulators' landscape highlights the clinical significance of acute myocardial infarction.
Chao P, Zhang X, Zhang L, Wang Y, Wusiman M, Aimaijiang G, Chen X, Yang Y
Frontiers in immunology 2024;15:1308978
Frontiers in immunology 2024;15:1308978
Multi-omic analysis of precocious puberty girls: pathway changes and metabolite validation.
Zhou F, Mao J, Jin Z, Zhu L, Li X
Frontiers in endocrinology 2024;15:1285666
Frontiers in endocrinology 2024;15:1285666
TRIM28 facilitates type I interferon activation by targeting TBK1.
Hua F, Nass T Jr, Parvatiyar K
Frontiers in immunology 2024;15:1279920
Frontiers in immunology 2024;15:1279920
Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins.
Daurat M, Gauthier C, El Cheikh K, Ali LMA, Morère E, Bettache N, Gary-Bobo M, Morère A, Garcia M, Maynadier M, Basile I
Frontiers in immunology 2024;15:1273280
Frontiers in immunology 2024;15:1273280
Protective effect of oxytocin on vincristine-induced gastrointestinal dysmotility in mice.
Li S, Shi Y, Zhu J, Li J, Wang S, Liu C
Frontiers in pharmacology 2024;15:1270612
Frontiers in pharmacology 2024;15:1270612
Integrated analysis reveals crosstalk between pyroptosis and immune regulation in renal fibrosis.
Bai F, Han L, Yang J, Liu Y, Li X, Wang Y, Jiang R, Zeng Z, Gao Y, Zhang H
Frontiers in immunology 2024;15:1247382
Frontiers in immunology 2024;15:1247382
Association of tumour mutation burden with prognosis and its clinical significance in stage III gastric cancer.
Han YL, Chen L, Wang XN, Xu ML, Qin R, Gong FM, Sun P, Liu HY, Teng ZP, Li ZX, Dai GH
BioImpacts : BI 2024;14(6):30118
BioImpacts : BI 2024;14(6):30118
In-silico analysis of TMEM2 as a pancreatic adenocarcinoma and cancer-associated fibroblast biomarker, and functional characterization of NSC777201, for targeted drug development.
Srivastava P, Yadav VK, Chang TH, Su EC, Lawal B, Wu AT, Huang HS
American journal of cancer research 2024;14(6):3010-3035
American journal of cancer research 2024;14(6):3010-3035
ADAM9 drives the immunosuppressive microenvironment by cholesterol biosynthesis-mediated activation of IL6-STAT3 signaling for lung tumor progression.
Liu JP, Shen KY, Cheng WC, Chang WC, Hsieh CY, Lo CC, Kuo TT, Lin CC, Liu SJ, Huang WC, Sher YP
American journal of cancer research 2024;14(4):1850-1865
American journal of cancer research 2024;14(4):1850-1865
SSH3 promotes pancreatic cancer proliferation and migration by activating the notch signaling pathway.
Yang C, Quan G, Zhang S, Jiang J
American journal of cancer research 2024;14(4):1815-1830
American journal of cancer research 2024;14(4):1815-1830
Polycomb repressive complex 1 modulates granulosa cell proliferation in early folliculogenesis to support female reproduction.
Gao M, Zhang T, Chen T, Chen Z, Zhu Z, Wen Y, Qin S, Bao Y, Zhao T, Li H, Liu L, Hao M, Wang J, Wang F, Wang H, Zhou B, Zhang H, Xia G, Wang C
Theranostics 2024;14(4):1371-1389
Theranostics 2024;14(4):1371-1389
Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.
Shen S, Zhang M, Wang X, Liu Q, Su H, Sun B, Guo Z, Tian B, Gan H, Gong C, Ma L
Theranostics 2024;14(3):1241-1259
Theranostics 2024;14(3):1241-1259
DEC1 is involved in TGF-β1-induced epithelial-mesenchymal transition of gastric cancer.
Li P, Zheng Y, Wang YS
American journal of cancer research 2024;14(2):630-642
American journal of cancer research 2024;14(2):630-642
Anillin contributes to prostate cancer progression through the regulation of IGF2BP1 to promote c-Myc and MAPK signaling.
Liu J, Wang S, Zhang C, Wei Z, Han D, Song Y, Song X, Chao F, Wu Z, Xu G, Chen G
American journal of cancer research 2024;14(2):490-506
American journal of cancer research 2024;14(2):490-506
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy.
Lei K, Li J, Tu Z, Gong C, Liu J, Luo M, Ai W, Wu L, Li Y, Zhou Z, Chen Z, Lv S, Ye M, Wu M, Long X, Zhu X, Huang K
Theranostics 2024;14(11):4481-4498
Theranostics 2024;14(11):4481-4498
Aryl hydrocarbon receptor confers protection against macrophage pyroptosis and intestinal inflammation through regulating polyamine biosynthesis.
Gao Y, Liu KY, Xiao W, Xie X, Liang Q, Tu Z, Yang L, Yu H, Guo H, Huang S, Han X, Fu J, Zhou Y
Theranostics 2024;14(11):4218-4239
Theranostics 2024;14(11):4218-4239
Comprehensive analysis of ferroptosis-related genes indicates that TRIM46 is a novel biomarker and promotes the progression of ovarian cancer via modulating ferroptosis and Wnt signaling pathway.
Liu S, Xiao C, Rong Y, Liu M, Yang K, Tang J, Wang Z
American journal of cancer research 2024;14(10):4686-4707
American journal of cancer research 2024;14(10):4686-4707
Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro.
Wang C, Huang YM, Zhao J, Bai YM, Yan CQ, Du GH, Zheng LS, Liu AL
Frontiers in cellular and infection microbiology 2024;14:1484245
Frontiers in cellular and infection microbiology 2024;14:1484245
Characterization of the function and clinical value of ERCC family genes in lung adenocarcinoma.
Lu Z, Hou G
Frontiers in oncology 2024;14:1476100
Frontiers in oncology 2024;14:1476100
Revealing the mechanisms of RAC3 in tumor aggressiveness, the immunotherapy response, and drug resistance in bladder cancer.
Gao H, Qiu Y, Zheng X, Xu T, Liu G
Frontiers in oncology 2024;14:1466319
Frontiers in oncology 2024;14:1466319
Targeted inhibition of BET proteins in HPV16-positive head and neck squamous cell carcinoma reveals heterogeneous transcriptional responses.
Rao A, Stosic MS, Mohanty C, Suresh D, Wang AR, Lee DL, Nickel KP, Chandrashekar DS, Kimple RJ, Lambert PF, Kendziorski C, Rounge TB, Iyer G
Frontiers in oncology 2024;14:1440836
Frontiers in oncology 2024;14:1440836
USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53.
Li X, Pan J, Zheng P
Frontiers in oncology 2024;14:1427663
Frontiers in oncology 2024;14:1427663
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Mao J, Tao Y, Wang K, Sun H, Zhang M, Jin L, Pan Y
Frontiers in oncology 2024;14:1371990
Frontiers in oncology 2024;14:1371990
Identification and validation of a gap junction protein related signature for predicting the prognosis of renal clear cell carcinoma.
Huang Y, Guo W, Zeng Y, Wang X, Fan B, Zhang Y, Yan L, Gu G, Liu Z
Frontiers in oncology 2024;14:1354049
Frontiers in oncology 2024;14:1354049
MAPK-activated protein kinase 2 is associated with poor prognosis of glioma patients and immune inhibition in glioma.
Sun J, Wu S, Zhao W, Xue S, Zhang L, Ren J
Frontiers in oncology 2024;14:1307992
Frontiers in oncology 2024;14:1307992
Glutamine promotes the proliferation of intestinal stem cells via inhibition of TP53-induced glycolysis and apoptosis regulator promoter methylation in burned mice.
Zhang P, Wu D, Zha X, Su S, Zhang Y, Wei Y, Xia L, Fan S, Peng X
Burns & trauma 2024;12:tkae045
Burns & trauma 2024;12:tkae045
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Du J, Liu W, Song Y, Zhang Y, Dong C, Xiong S, Huang Z, Wang T, Ding J, He Q, Yu Z, Ma X
Burns & trauma 2024;12:tkad057
Burns & trauma 2024;12:tkad057
Anti-inflammatory role of low-intensity pulsed ultrasound in inhibiting lipopolysaccharide-induced M1 polarization of RAW264.7 cells via Wnt2b/AXIN/β-catenin.
Yin J, Bao Y, Xu M, Li P, Zhang Z, Xue H, Yang X
PeerJ 2024;12:e18448
PeerJ 2024;12:e18448
PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway.
Qin T, Huang M, Wei W, Zhou W, Tang Q, Huang Q, Tang N, Gai S
PeerJ 2024;12:e17555
PeerJ 2024;12:e17555
Single-cell transcriptome reveals the heterogeneity of malignant ductal cells and the prognostic value of REG4 and SPINK1 in primary pancreatic ductal adenocarcinoma.
Ji Y, Xu Q, Wang W
PeerJ 2024;12:e17350
PeerJ 2024;12:e17350
Circular RNA circMAN1A2 promotes ovarian cancer progression through the microRNA-135a-3p/IL1RAP/TAK1 pathway.
Li B, Hu C, Zhao D, Nie M, Wang X
PeerJ 2024;12:e16967
PeerJ 2024;12:e16967
Reversal of cholestatic liver disease by the inhibition of sphingosine 1-phosphate receptor 2 signaling.
Cao H, Chen L, Zeng Z, Wu X, Lei Y, Jia W, Yue G, Yi B, Li YJ, Shi Y
PeerJ 2024;12:e16744
PeerJ 2024;12:e16744
Quercetin alleviates PM(2.5)-induced chronic lung injury in mice by targeting ferroptosis.
Ding S, Jiang J, Li Y
PeerJ 2024;12:e16703
PeerJ 2024;12:e16703
Inhibition effect of copper-bearing metals on arterial neointimal hyperplasia via the AKT/Nrf2/ARE pathway in vitro and in vivo.
Wang P, Xu X, Gu G, Guo Q, Rao Y, Yang K, Xi T, Yuan Y, Chen S, Qi X
Regenerative biomaterials 2024;11:rbae042
Regenerative biomaterials 2024;11:rbae042
Sesamin alleviates lipid accumulation induced by elaidic acid in L02 cells through TFEB regulated autophagy.
Liang X, Zhang T, Cheng X, Yuan H, Yang N, Yi Y, Li X, Zhang F, Sun J, Li Z, Wang X
Frontiers in nutrition 2024;11:1511682
Frontiers in nutrition 2024;11:1511682
Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice.
Zhang L, Wang H, Wang Z, Xu J, Wang M, Wang W, He Q, Yu Y, Yuan D, Bu G, Qiu R, Long J
Frontiers in cardiovascular medicine 2024;11:1450898
Frontiers in cardiovascular medicine 2024;11:1450898
Identification of a novel Scn3b mutation in a Chinese Brugada syndrome pedigree: implications for Nav1.5 electrophysiological properties and intracellular distribution of Nav1.5 and Navβ3.
Fan J, Wang SH, Cao LL, Li WJ, Sun SX, Luo SL, Pan YC, Tan WL, Wu TY, Liu Z, Yu BB
Frontiers in cardiovascular medicine 2024;11:1320687
Frontiers in cardiovascular medicine 2024;11:1320687
Circ_0007386 Promotes the Progression of Hepatocellular Carcinoma Through the miR-507/ CCNT2 Axis.
Feng Y, Liang L, Jia W, Wang J, Xu C, Zhu D, Xu B, Zhao W, Ling X, Zhou Y, Kong L, Ding W
Journal of hepatocellular carcinoma 2024;11:1095-1112
Journal of hepatocellular carcinoma 2024;11:1095-1112
Changes of m(6)A Regulatory Proteins and Nrf2 Signaling Molecules in Liver Tissue of Type 2 Diabetes Mellitus Rats.
Wang N, Yang J, Liu X, Liu G, He Z, Gu S
Cell biochemistry and biophysics 2024 Sep;82(3):2217-2226
Cell biochemistry and biophysics 2024 Sep;82(3):2217-2226
Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane.
Zhang X, Tan Y, Li T, Tan D, Fu B, Yang M, Chen Y, Cao M, Xuan C, Du Q, Hu R, Wang Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Sep;76:101112
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Sep;76:101112
GSDMB involvement in the pathogenesis of abdominal aortic aneurysm through regulation of macrophage non-canonical pyroptosis.
Xie X, Shen X, Liu Y, Zuo Y, Wang S, Zhou Y, Li X, Wang K, Li B, Wang Z
Archives of biochemistry and biophysics 2024 Sep;759:110102
Archives of biochemistry and biophysics 2024 Sep;759:110102
ABCG2 shields against epilepsy, relieves oxidative stress and apoptosis via inhibiting the ISGylation of STAT1 and mTOR.
Li C, Cai Y, Chen Y, Tong J, Li Y, Liu D, Wang Y, Li Z, Wang Y, Li Q
Redox biology 2024 Sep;75:103262
Redox biology 2024 Sep;75:103262
CircFAM188A Regulates Autophagy via miR-670-3p and ULK1 in Epithelial Ovarian Carcinoma.
Yong M, Zeng Y, Yao Y, Yang M, Tang F, Zhu H, Hu J
Cancer reports (Hoboken, N.J.) 2024 Sep;7(9):e2128
Cancer reports (Hoboken, N.J.) 2024 Sep;7(9):e2128
Dexmedetomidine improves mitophagy and pyroptosis through the ALKBH5/FUNDC1 axis during epidural-related maternal fever.
Xiao F, Yao H, Qian J, Huang J, Xia G
Advances in medical sciences 2024 Sep;69(2):272-280
Advances in medical sciences 2024 Sep;69(2):272-280
A fungal-binding agglutinin in the skin slime of Japanese flounder (Paralichthys olivaceus) is glyceraldehyde 3-phosphate dehydrogenase.
Tsutsui S, Terashima M, Nakamura O
Microbiology and immunology 2024 Sep;68(9):331-338
Microbiology and immunology 2024 Sep;68(9):331-338
MiR-483-3p promotes dental pulp stem cells osteogenic differentiation via the MAPK signaling pathway by targeting ARRB2.
Yu X, Ge J, Xie H, Qian J, Xia W, Wang Q, Zhou X, Zhou Y
In vitro cellular & developmental biology. Animal 2024 Sep;60(8):879-887
In vitro cellular & developmental biology. Animal 2024 Sep;60(8):879-887
Increased CCT5 expression is a potential unfavourable factor promoting the growth of nasopharyngeal carcinoma.
Wu S, Peng L
The Journal of international medical research 2024 Sep;52(9):3000605241271754
The Journal of international medical research 2024 Sep;52(9):3000605241271754
Surgical Debulking Modifies Notch Signaling and May Improve Vismodegib Effectiveness for Locally Advanced Basal Cell Carcinoma.
Maglakelidze N, Gettle SL, Longenecker AL, Vidimos AT, Billingsley EM, Hobbs RP, Lam C
JID innovations : skin science from molecules to population health 2024 Sep;4(5):100288
JID innovations : skin science from molecules to population health 2024 Sep;4(5):100288
Effects of multi-walled carbon nanotubes and halloysite nanotubes on plasma lipid profiles and autophagic lipolysis pathways in mouse aortas and hearts.
Cheng Y, Zhang Y, Wang C, Zhao W, Huang C, Zhang Z, Sheng L, Song F, Cao Y
Environmental toxicology 2024 Sep;39(9):4431-4446
Environmental toxicology 2024 Sep;39(9):4431-4446
Tangeretin alleviates inflammation and oxidative response induced by spinal cord injury by activating the Sesn2/Keap1/Nrf2 pathway.
Peng B, Hu J, Sun Y, Huang Y, Peng Q, Zhao W, Xu W, Zhu L
Phytotherapy research : PTR 2024 Sep;38(9):4555-4569
Phytotherapy research : PTR 2024 Sep;38(9):4555-4569
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
Hu Z, Tan H, Zhang Y, Qi T, Li Y, Li N, Zhou Z, Wang Y, Wang H, Zhang H, Wang Q
Experimental neurology 2024 Sep;379:114886
Experimental neurology 2024 Sep;379:114886
The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine.
Shi X, Zhang Y, Wang Y, Wang J, Gao Y, Wang R, Wang L, Xiong M, Cao Y, Ou N, Liu Q, Ma H, Cai J, Chen H
Cell death and differentiation 2024 Sep;31(9):1219-1234
Cell death and differentiation 2024 Sep;31(9):1219-1234
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death.
Liang J, Tian X, Zhou M, Yan F, Fan J, Qin Y, Chen B, Huo X, Yu Z, Tian Y, Deng S, Peng Y, Wang Y, Liu B, Ma X
Biomaterials 2024 Sep;309:122608
Biomaterials 2024 Sep;309:122608
Photosensitive AIEgens sensitize bacteria to oxidative damage and modulate the inflammatory responses of macrophages to salvage the photodynamic therapy against MRSA.
Wu Y, Li J, Zhu L, Wang D, Song J, Yu X, Li Y, Tang BZ
Biomaterials 2024 Sep;309:122583
Biomaterials 2024 Sep;309:122583
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Cai Y, Zhou J, Xu A, Huang J, Zhang H, Xie G, Zhong K, Wu Y, Ye P, Wang H, Niu H
The Journal of biological chemistry 2024 Sep;300(9):107598
The Journal of biological chemistry 2024 Sep;300(9):107598
Identification and immunological characterization of genes associated with ferroptosis in Alzheimer's disease and experimental demonstration.
Xiao Z, Hu R, Liu WL, He XX, Dong MY, Huang ZS
Molecular medicine reports 2024 Sep;30(3)
Molecular medicine reports 2024 Sep;30(3)
DCBLD2 deletion increases hyperglycemia and induces vascular remodeling by inhibiting insulin receptor recycling in endothelial cells.
Guo L, Zong Y, Yang W, Lin Y, Feng Q, Yu C, Liu X, Li C, Zhang W, Wang R, Li L, Pei Y, Wang H, Liu D, Niu H, Nie L
The FEBS journal 2024 Sep;291(18):4076-4095
The FEBS journal 2024 Sep;291(18):4076-4095
Rhodojaponin VI ameliorates podocyte injury related with MDM2/Notch1 pathway in rat experimental membranous nephropathy.
Song A, Yan R, Qiu Y, Yin X, Xiong J, Yao G, Zhang C
Nephrology (Carlton, Vic.) 2024 Sep;29(9):555-564
Nephrology (Carlton, Vic.) 2024 Sep;29(9):555-564
Anti‑epileptic mechanism of isopimaric acid from Platycladi cacumen based on network pharmacology, molecular docking and biological validation.
Wang Y, Wang Y, Li C, Liu D, Cai Y, Li Q
Experimental and therapeutic medicine 2024 Sep;28(3):348
Experimental and therapeutic medicine 2024 Sep;28(3):348
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
Jiang Y, Liu B, Fu L, Li F
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
Fucoidan alleviates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via Nrf2/GPX4 pathway.
Wang Y, Han J, Zhan S, Guo C, Yin S, Zhan L, Zhou Q, Liu R, Yan H, Wang X, Yan D
International journal of biological macromolecules 2024 Sep;276(Pt 1):133792
International journal of biological macromolecules 2024 Sep;276(Pt 1):133792
Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis.
Song A, Yan R, Xiong W, Xiang H, Huang J, Jiang A, Zhang C
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:13-25
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:13-25
Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis.
Wang Z, Tang P, Xiao H, Peng S, Chen J, Wang Y, Xu J, Yan Q, Zhang J, Deng J, Ma Q, Zhu H, Luo W, Zhang D, Wang L, Qin J, Lan W, Jiang J, Liu Q
The Journal of pathology 2024 Sep;264(1):68-79
The Journal of pathology 2024 Sep;264(1):68-79
Cyclic guanosine monophosphate-adenosine monophosphate synthetase/stimulator of interferon genes signaling aggravated corneal allograft rejection through neutrophil extracellular traps.
Wei C, Huang Q, Zeng F, Ma L, Bai X, Zhu X, Gao H, Qi X
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2024 Sep;24(9):1583-1596
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2024 Sep;24(9):1583-1596
Inhibition of KIAA1429/HK1 axis enhances the sensitivity of liver cancer cells to sorafenib by regulating the Warburg effect.
Liu D, Shan M, Zeng R, He M, Dai X, Lu L, Yang M, He H, Zhang Y, Xiang L, Chen A, Sun L, He F, Lian J
Biochemical pharmacology 2024 Sep;227:116419
Biochemical pharmacology 2024 Sep;227:116419
STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage.
Chen Z, Li X, Sun X, Xiao S, Chen T, Ren L, Liu N
Free radical biology & medicine 2024 Sep;222:437-455
Free radical biology & medicine 2024 Sep;222:437-455
Pyrimidine compounds BY4003 and BY4008 inhibit glioblastoma cells growth via modulating JAK3/STAT3 signaling pathway.
Ahmad N, Chen L, Yuan Z, Ma X, Yang X, Wang Y, Zhao Y, Jin H, Khaidamah N, Wang J, Lu J, Liu Z, Wu M, Wang Q, Qi Y, Wang C, Zhao Y, Piao Y, Huang R, Diao Y, Deng S, Shu X
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Sep;21(5):e00431
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Sep;21(5):e00431
Functional regulation of microRNA-184 in the replication and infection of Autographa californica multiple nucleopolyhedrovirus.
Li J, Kang Z, Xu H, Li S, Li G, Sun X, Lei C, Chen Y
Pesticide biochemistry and physiology 2024 Sep;204:106062
Pesticide biochemistry and physiology 2024 Sep;204:106062
TRIM56 restricts Coxsackievirus B infection by mediating the ubiquitination of viral RNA-dependent RNA polymerase 3D.
Wang Y, Dong Y, Luan T, Chen Y, Lin L, Li S, Feng D, Wei J, Fei Y, Wang G, Pan J, Wang Y, Zhong Z, Zhao W
PLoS pathogens 2024 Sep;20(9):e1012594
PLoS pathogens 2024 Sep;20(9):e1012594
Bacterial ubiquitin ligases hijack the host deubiquitinase OTUB1 to inhibit MTORC1 signaling and promote autophagy.
Ma K, Xian W, Liu H, Shu R, Ge J, Luo ZQ, Liu X, Qiu J
Autophagy 2024 Sep;20(9):1968-1983
Autophagy 2024 Sep;20(9):1968-1983
The potential of ribonucleotide reductase M2 as a novel prognostic maker and therapeutic target to inhibit medulloblastoma proliferation, migration, and invasiveness.
Wu X, Gou P, Fang C, Zhou Y, Li L, Zhai X, Liang P
Pediatric discovery 2024 Sep;2(3):e81
Pediatric discovery 2024 Sep;2(3):e81
Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms.
Sun H, Yang B, Li Q, Zhu X, Song E, Liu C, Song Y, Jiang G
Nature nanotechnology 2024 Sep;19(9):1354-1365
Nature nanotechnology 2024 Sep;19(9):1354-1365
Transcriptional regulation of Znt family members znt4, znt5 and znt10 and their function in zinc transport in yellow catfish (Pelteobagrus fulvidraco).
Liu LL, Song CC, Abu-Elala N, Tan XY, Zhao T, Zheng H, Yang H, Luo Z
Biochimica et biophysica acta. Gene regulatory mechanisms 2024 Sep;1867(3):195041
Biochimica et biophysica acta. Gene regulatory mechanisms 2024 Sep;1867(3):195041
AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease.
Sun F, Wang J, Meng L, Zhou Z, Xu Y, Yang M, Li Y, Jiang T, Liu B, Yan H
British journal of pharmacology 2024 Sep;181(17):3039-3063
British journal of pharmacology 2024 Sep;181(17):3039-3063
Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice.
Yang S, Zhao X, Zhang Y, Tang Q, Li Y, Du Y, Yu P
Peptides 2024 Sep;179:171271
Peptides 2024 Sep;179:171271
Osteoclast-derived exosomes influence osteoblast differentiation in osteoporosis progression via the lncRNA AW011738/ miR-24-2-5p/ TREM1 axis.
Liu J, Wang B, Chen H, Yu X, Cao X, Zhang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117231
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117231
Enriched environment treatment promotes neurofunctional recovery by regulating the ALK5/Smad2/3/Gadd45β signaling pathway in rats with cerebral ischemia /reperfusion injury.
Liu G, Xie C, Li J, Jiang X, Tang H, Li C, Zhang K
Neurochemistry international 2024 Sep;178:105806
Neurochemistry international 2024 Sep;178:105806
Red nucleus mGluR1 and mGluR5 facilitate the development of neuropathic pain through stimulating the expressions of TNF-α and IL-1β.
Tian X, Wang WT, Zhang MM, Yang QQ, Xu YL, Wu JB, Xie XX, Wang JY, Wang JY
Neurochemistry international 2024 Sep;178:105786
Neurochemistry international 2024 Sep;178:105786
Inhibition of GBP1 alleviates pyroptosis of human pulmonary microvascular endothelial cells through STAT1/NLRP3/GSDMD pathway.
Hao Y, Fu H, Li K, Zou X, Zhou X, Tang X, Liu C, Zhou F
Molecular immunology 2024 Sep;173:1-9
Molecular immunology 2024 Sep;173:1-9
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
Wu X, Liu R, Zhang Z, Yang J, Liu X, Jiang L, Fang M, Wang S, Lai L, Song Y, Li Z
EMBO molecular medicine 2024 Sep;16(9):2002-2023
EMBO molecular medicine 2024 Sep;16(9):2002-2023
PKC-δ Promotes IL-1β-Induced Apoptosis of Rat Chondrocytes and Via Activating JNK and P38 MAPK Pathways.
Lu J, Yu M, Li J
Cartilage 2024 Sep;15(3):315-327
Cartilage 2024 Sep;15(3):315-327
HIF-1α knockdown attenuates inflammation and oxidative stress in ischemic stroke male rats via CXCR4/NF-κB pathway.
Chen G, Wang X, Jin Z, Hu GB, Yu QH, Jiang HY
Brain and behavior 2024 Sep;14(9):e70039
Brain and behavior 2024 Sep;14(9):e70039
Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism.
Li B, Xiao Q, Zhao H, Zhang J, Yang C, Zou Y, Zhang B, Liu J, Sun H, Liu H
Acta pharmaceutica Sinica. B 2024 Sep;14(9):3949-3963
Acta pharmaceutica Sinica. B 2024 Sep;14(9):3949-3963
The role of cytidine 5'-triphosphate synthetase 1 in metabolic rewiring during epithelial-to-mesenchymal transition in non-small-cell lung cancer.
Nakasuka F, Hirayama A, Makinoshima H, Yano S, Soga T, Tabata S
FEBS open bio 2024 Sep;14(9):1570-1583
FEBS open bio 2024 Sep;14(9):1570-1583
Puerarin suppresses macrophage M1 polarization to alleviate renal inflammatory injury through antagonizing TLR4/MyD88-mediated NF-κB p65 and JNK/FoxO1 activation.
Hu Z, Chen D, Yan P, Zheng F, Zhu H, Yuan Z, Yang X, Zuo Y, Chen C, Lu H, Wu L, Lyu J, Bai Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155813
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155813
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
Xu X, Wang Y, Song Q, Zheng H, Lv J, Fu Z, Mao X, Li Y, Wu H, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
Role of RIPK3 in lipid metabolism and postnatal overfeeding-induced metabolic disorders in mice.
Zhu D, Zheng W, Kuang J, Wang Y, Deng X, Li X, Zhou W
The Journal of nutritional biochemistry 2024 Sep;131:109688
The Journal of nutritional biochemistry 2024 Sep;131:109688
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Wu X, Xia Y, Dai H, Hong C, Zhao Y, Wei W, Zheng D
Advanced healthcare materials 2024 Sep;13(22):e2400770
Advanced healthcare materials 2024 Sep;13(22):e2400770
GLP-2 ameliorates D-galactose induced muscle aging by IGF-1/Pi3k/Akt/FoxO3a signaling pathway in C2C12 cells and mice.
Ye YL, Kuai Z, Qian DD, He YT, Shen JP, Wu KF, Ren WY, Hu Y
Archives of gerontology and geriatrics 2024 Sep;124:105462
Archives of gerontology and geriatrics 2024 Sep;124:105462
The role of α7nAchR and PD-L1 in neuroimmune regulation of keloid treatment.
Luo Z, Zheng S, Liu J, Qi F
Cellular signalling 2024 Sep;121:111275
Cellular signalling 2024 Sep;121:111275
USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1.
Zhou M, Gao Y, Wu S, Wang Y, Yang J
Cellular signalling 2024 Sep;121:111265
Cellular signalling 2024 Sep;121:111265
Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis.
Qiu P, Chang Y, Chen X, Wang S, Nie H, Hong Y, Zhang M, Wang H, Xiao C, Chen Y, Liu L, Zhao Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2403461
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2403461
Genetically Engineered Membrane-Coated Nanoparticles for Enhanced Prostate-Specific Membrane Antigen Targeting and Ferroptosis Treatment of Castration-Resistant Prostate Cancer.
Li Y, Li H, Zhang K, Xu C, Wang J, Li Z, Zhou Y, Liu S, Zhao X, Li Z, Yang F, Hu W, Jing Y, Wu P, Zhang J, Shi C, Zhang R, Jiang W, Xing N, Wen W, Han D, Qin W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2401095
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2401095
Hsp90 Promotes Gastric Cancer Cell Metastasis and Stemness by Regulating the Regional Distribution of Glycolysis-Related Metabolic Enzymes in the Cytoplasm.
Liu S, Shen G, Zhou X, Sun L, Yu L, Cao Y, Shu X, Ran Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2310109
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2310109
Bortezomib elevates intracellular free Fe(2+) by enhancing NCOA4-mediated ferritinophagy and synergizes with RSL-3 to inhibit multiple myeloma cells.
Zhang Y, He F, Hu W, Sun J, Zhao H, Cheng Y, Tang Z, He J, Wang X, Liu T, Luo C, Lu Z, Xiang M, Liao Y, Wang Y, Li J, Xia J
Annals of hematology 2024 Sep;103(9):3627-3637
Annals of hematology 2024 Sep;103(9):3627-3637
Selenium nanoparticles promotes intestinal development in broilers by inhibiting intestinal inflammation and NLRP3 signaling pathway compared with other selenium sources.
Chen Y, Luo C, Li S, Liu X, Guo Y, Li Y, Wang Y, Yuan J
Poultry science 2024 Sep;103(9):103958
Poultry science 2024 Sep;103(9):103958
Resolving the current controversy of use and reuse of housekeeping proteins in ageing research: Focus on saving people's tax dollars.
Kshirsagar S, Islam MA, Reddy AP, Reddy PH
Ageing research reviews 2024 Sep;100:102437
Ageing research reviews 2024 Sep;100:102437
SP1/CTR1-mediated oxidative stress-induced cuproptosis in intervertebral disc degeneration.
Chen X, Li K, Xiao Y, Wu W, Lin H, Qing X, Tian S, Liu S, Feng S, Wang B, Shao Z, Peng Y
BioFactors (Oxford, England) 2024 Sep-Oct;50(5):1009-1023
BioFactors (Oxford, England) 2024 Sep-Oct;50(5):1009-1023
MiRNA-132/212 encapsulated by adipose tissue-derived exosomes worsen atherosclerosis progression.
Guo B, Zhuang TT, Li CC, Li F, Shan SK, Zheng MH, Xu QS, Wang Y, Lei LM, Tang KX, Ouyang W, Duan JY, Wu YY, Cao YC, Ullah MHE, Zhou ZA, Lin X, Wu F, Xu F, Liao XB, Yuan LQ
Cardiovascular diabetology 2024 Sep 9;23(1):331
Cardiovascular diabetology 2024 Sep 9;23(1):331
Systematic identification of post-transcriptional regulatory modules.
Khoroshkin M, Buyan A, Dodel M, Navickas A, Yu J, Trejo F, Doty A, Baratam R, Zhou S, Lee SB, Joshi T, Garcia K, Choi B, Miglani S, Subramanyam V, Modi H, Carpenter C, Markett D, Corces MR, Mardakheh FK, Kulakovskiy IV, Goodarzi H
Nature communications 2024 Sep 9;15(1):7872
Nature communications 2024 Sep 9;15(1):7872
Human Umbilical Cord Mesenchymal Stem Cells-Derived Extracellular Vesicles for Rat Jawbone Regeneration in Periapical Periodontitis.
Gao J, Zhu D, Fan Y, Liu H, Shen Z
ACS biomaterials science & engineering 2024 Sep 9;10(9):5784-5795
ACS biomaterials science & engineering 2024 Sep 9;10(9):5784-5795
Distinct modes of coupling between VCP, an essential unfoldase, and deubiquitinases.
Vostal LE, Dahan NE, Zhang W, Reynolds MJ, Chait BT, Kapoor TM
bioRxiv : the preprint server for biology 2024 Sep 9;
bioRxiv : the preprint server for biology 2024 Sep 9;
GALNT6 promotes bladder cancer malignancy and immune escape by epithelial-mesenchymal transition and CD8(+) T cells.
Sun X, Wu H, Tang L, Al-Danakh A, Jian Y, Gong L, Li C, Yu X, Zeng G, Chen Q, Yang D, Wang S
Cancer cell international 2024 Sep 8;24(1):308
Cancer cell international 2024 Sep 8;24(1):308
A New Mouse Model for Usher Syndrome Crossing Kunming Mice with CBA/J Mice.
Li S, Jiang Y, Zhang L, Yan W, Wei D, Zhang M, Zhu B, Chen T, Wang X, Zhang Z, Su Y
Gene 2024 Sep 5;922:148562
Gene 2024 Sep 5;922:148562
Bioinspired Collagen Scaffold Loaded with bFGF-Overexpressing Human Mesenchymal Stromal Cells Accelerating Diabetic Skin Wound Healing via HIF-1 Signal Pathway Regulated Neovascularization.
Huang F, Gao T, Feng Y, Xie Y, Tai C, Huang Y, Ling L, Wang B
ACS applied materials & interfaces 2024 Sep 4;16(35):45989-46004
ACS applied materials & interfaces 2024 Sep 4;16(35):45989-46004
10-hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence in male mice preclinically.
Geng N, Fan M, Kuang B, Zhang F, Xian M, Deng L, Chen C, Pan Y, Chen J, Feng N, Liang L, Ye Y, Liu K, Li X, Du Y, Guo F
Nature communications 2024 Sep 4;15(1):7712
Nature communications 2024 Sep 4;15(1):7712
BAP1 regulates HSF1 activity and cancer immunity in pancreatic cancer.
Yuan W, Zhang Q, Zhao Y, Xia W, Yin S, Liang X, Chen T, Li G, Liu Y, Liu Z, Huang J
Journal of experimental & clinical cancer research : CR 2024 Sep 30;43(1):275
Journal of experimental & clinical cancer research : CR 2024 Sep 30;43(1):275
Copy number amplification-induced overexpression of lncRNA LOC101927668 facilitates colorectal cancer progression by recruiting hnRNPD to disrupt RBM47/p53/p21 signaling.
Wang Z, Han H, Zhang C, Wu C, Di J, Xing P, Qiao X, Weng K, Hao H, Yang X, Hou Y, Jiang B, Su X
Journal of experimental & clinical cancer research : CR 2024 Sep 30;43(1):274
Journal of experimental & clinical cancer research : CR 2024 Sep 30;43(1):274
Deubiquitinase USP5 regulates RIPK1 driven pyroptosis in response to myocardial ischemic reperfusion injury.
Sun W, Lu H, Ma L, Ding C, Wang H, Chu Y
Cell communication and signaling : CCS 2024 Sep 30;22(1):466
Cell communication and signaling : CCS 2024 Sep 30;22(1):466
Nobiletin alleviates macrophage M2 polarization by activating AMPK-mTOR-mediated autophagy in pulmonary fibrosis mice.
Cheng Y, Mei X, Shao W, Zheng J, Yin X, Zhang Q, Li J, Zhao P
International immunopharmacology 2024 Sep 30;139:112792
International immunopharmacology 2024 Sep 30;139:112792
Construction of a prognostic model with exosome biogenesis- and release-related genes and identification of RAB27B in immune infiltration of pancreatic cancer.
Li TY, Qin C, Zhao BB, Li ZR, Wang YY, Zhao YT, Wang WB
Translational cancer research 2024 Sep 30;13(9):4846-4865
Translational cancer research 2024 Sep 30;13(9):4846-4865
Gliomedin drives gastric cancer cell proliferation and migration, correlating with a poor prognosis.
You X, Wang M, Wang X, Wang X, Cheng Y, Zhang C, Miao Q, Feng Y
Heliyon 2024 Sep 30;10(18):e38153
Heliyon 2024 Sep 30;10(18):e38153
ER stress modulates Kv1.5 channels via PERK branch in HL-1 atrial myocytes: Relevance to atrial arrhythmogenesis and the effect of tetramethylpyrazine.
Wang XC, Zhou Y, Chen HX, Hou HT, He GW, Yang Q
Heliyon 2024 Sep 30;10(18):e37767
Heliyon 2024 Sep 30;10(18):e37767
Identification of diagnostic markers and molecular clusters of cuproptosis-related genes in alcohol-related liver disease based on machine learning and experimental validation.
Li J, Wang Y, Wu Z, Zhong M, Feng G, Liu Z, Zeng Y, Wei Z, Mueller S, He S, Ouyang G, Yuan G
Heliyon 2024 Sep 30;10(18):e37612
Heliyon 2024 Sep 30;10(18):e37612
Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.
Yang S, Du Y, Li Y, Tang Q, Zhang Y, Zhao X
Journal of neuroinflammation 2024 Sep 3;21(1):218
Journal of neuroinflammation 2024 Sep 3;21(1):218
KIFC3 promotes the proliferation, migration and invasion of non-small cell lung cancer through the PI3K/AKT signaling pathway.
Ma Y, Zhang Y, Jiang X, Guan J, Wang H, Zhang J, Tong Y, Qiu X, Zhou R
Scientific reports 2024 Sep 3;14(1):20471
Scientific reports 2024 Sep 3;14(1):20471
2D MXene Nanosheets with ROS Scavenging Ability Effectively Delay Osteoarthritis Progression.
Zhao H, Wang T, Fang X, Xu T, Li J, Jing S, Chen G, Liu Y, Sheng G
Nanomaterials (Basel, Switzerland) 2024 Sep 29;14(19)
Nanomaterials (Basel, Switzerland) 2024 Sep 29;14(19)
Trehalose Rescues Postmenopausal Osteoporosis Induced by Ovariectomy through Alleviating Osteoblast Pyroptosis via Promoting Autophagy.
Hu X, Wang W, Chen X, Kong C, Zhao X, Wang Z, Zhang H, Lu S
Biomedicines 2024 Sep 29;12(10)
Biomedicines 2024 Sep 29;12(10)
Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity.
Lian C, Zhang C, Tian P, Tan Q, Wei Y, Wang Z, Zhang Q, Zhang Q, Zhong M, Zhou LQ, Ke X, Zhang H, Zhu Y, Li Z, Cheng J, Wei GH
Signal transduction and targeted therapy 2024 Sep 28;9(1):258
Signal transduction and targeted therapy 2024 Sep 28;9(1):258
Differential proteins from EVs identification based on tandem mass tags analysis and effect of Treg-derived EVs on T-lymphocytes in COPD patients.
Tao X, Xu Z, Tian H, He J, Wang G, Tao X
Respiratory research 2024 Sep 28;25(1):349
Respiratory research 2024 Sep 28;25(1):349
Empagliflozin alleviates obesity-related cardiac dysfunction via the activation of SIRT3-mediated autophagosome formation.
Luo Y, Ye T, Tian H, Song H, Kan C, Han F, Hou N, Sun X, Zhang J
Lipids in health and disease 2024 Sep 27;23(1):308
Lipids in health and disease 2024 Sep 27;23(1):308
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
Wang D, Li Y, Chang W, Feng M, Yang Y, Zhu X, Liu Z, Fu Y
Cell death & disease 2024 Sep 27;15(9):693
Cell death & disease 2024 Sep 27;15(9):693
DDIT3 switches osteogenic potential of BMP9 to lipogenic by attenuating Wnt/β-catenin signaling via up-regulating DKK1 in mesenchymal stem cells.
Luo HH, Ren WY, Ye AH, Liu L, Jiang Y, Ye FL, He BC, Chen ZH
Aging 2024 Sep 26;16(18):12543-12558
Aging 2024 Sep 26;16(18):12543-12558
A Gain-of-Function Cleavage of TonEBP by Coronavirus NSP5 to Suppress IFN-β Expression.
Park H, Lee SM, Jeong SJ, Kweon YC, Shin GW, Kim WY, Lee-Kwon W, Park CY, Kwon HM
Cells 2024 Sep 26;13(19)
Cells 2024 Sep 26;13(19)
Exposure to Succinate Leads to Steatosis in Non-Obese Non-Alcoholic Fatty Liver Disease by Inhibiting AMPK/PPARα/FGF21-Dependent Fatty Acid Oxidation.
Yang H, Ran S, Zhou Y, Shi Q, Yu J, Wang W, Sun C, Li D, Hu Y, Pan C, Yuan Q, Zhen Y, Liu Q, Song L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21052-21064
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21052-21064
Treadmill Exercise Facilitates Synaptic Plasticity in APP/PS1 Mice by Regulating Hippocampal AMPAR Activity.
Yu L, Li Y, Lv Y, Gu B, Cai J, Liu QS, Zhao L
Cells 2024 Sep 25;13(19)
Cells 2024 Sep 25;13(19)
Etelcalcetide ameliorates bone loss in chronic kidney disease-mineral and bone disorder by activation of IRF7 and necroptosis pathways.
Chiu HW, Lu KC, Lin YC, Hou YC, Liao MT, Chen YJ, Chiu YJ, Zheng CM
International journal of biological macromolecules 2024 Sep 24;280(Pt 3):135978
International journal of biological macromolecules 2024 Sep 24;280(Pt 3):135978
Baicalin Ameliorates Depression-like Behaviors via Inhibiting Neuroinflammation and Apoptosis in Mice.
Yi Y, Liu G, Li Y, Wang C, Zhang B, Lou H, Yu S
International journal of molecular sciences 2024 Sep 24;25(19)
International journal of molecular sciences 2024 Sep 24;25(19)
Invention of circRNA promoting RNA to specifically promote circRNA production.
He Z, Ji H, Xia B, Cao X, Huang Y, Zhu Q
Nucleic acids research 2024 Sep 23;52(17):e83
Nucleic acids research 2024 Sep 23;52(17):e83
AntigenBoost: enhanced mRNA-based antigen expression through rational amino acid substitution.
Gao Y, Zhu S, Li H, Hao X, Chen W, Pan D, Qian Z
Briefings in bioinformatics 2024 Sep 23;25(6)
Briefings in bioinformatics 2024 Sep 23;25(6)
TiO2 nanotube enhance osteogenesis through Kindlin-2/Integrin β1/YAP pathway-mediated mechanotransduction.
Deng Q, Yao Q, Wu A, Li J, Li Y, Tang L, Zeng H, Chen S, Guo T
Biomedical materials (Bristol, England) 2024 Sep 23;
Biomedical materials (Bristol, England) 2024 Sep 23;
Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis.
Liu K, Gao Q, Jia Y, Wei J, Chaudhuri SM, Wang S, Tang A, Mani NL, Iyer R, Cheng Y, Gao B, Lu W, Sun Z, Zhang B, Liu H, Fang D
iScience 2024 Sep 20;27(9):110592
iScience 2024 Sep 20;27(9):110592
Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2.
Ong HW, Yang X, Smith JL, Taft-Benz S, Howell S, Dickmander RJ, Havener TM, Sanders MK, Brown JW, Couñago RM, Chang E, Krämer A, Moorman NJ, Heise M, Axtman AD, Drewry DH, Willson TM
Molecules (Basel, Switzerland) 2024 Sep 2;29(17)
Molecules (Basel, Switzerland) 2024 Sep 2;29(17)
GAS6 as a potential target to alleviate neuroinflammation during Japanese encephalitis in mouse models.
Bian P, Zhang H, Ye C, Luo C, Jiang H, Wang Y, Dong Y, Yang J, Zhang F, Wang X, Zhang Y, Jia Z, Lei Y
Journal of neuroinflammation 2024 Sep 19;21(1):231
Journal of neuroinflammation 2024 Sep 19;21(1):231
Myotis bat STING attenuates aging-related inflammation in female mice.
Wang X, Jia JK, Wang Q, Gong JW, Li A, Su J, Zhou P
Zoological research 2024 Sep 18;45(5):961-971
Zoological research 2024 Sep 18;45(5):961-971
Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD.
Wang J, Wang R, Li Y, Huang J, Liu Y, Wang J, Xian P, Zhang Y, Yang Y, Zhang H, Li J
Cell reports. Medicine 2024 Sep 17;5(9):101732
Cell reports. Medicine 2024 Sep 17;5(9):101732
Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells.
Xu W, Gong L, Tang W, Lu G
BMC cardiovascular disorders 2024 Sep 17;24(1):494
BMC cardiovascular disorders 2024 Sep 17;24(1):494
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Chen D, Wu L, Liu X, Wang Q, Gui S, Bao L, Wang Z, He X, Zhao Y, Zhou J, Xie Y
Scientific reports 2024 Sep 17;14(1):21648
Scientific reports 2024 Sep 17;14(1):21648
HSV-1 immune escapes in microglia by down-regulating GM130 to inhibit TLR3-mediated innate immune responses.
Liu J, Chen X, Liu J, Zhang H, Lu W
Virology journal 2024 Sep 16;21(1):219
Virology journal 2024 Sep 16;21(1):219
TRIM16 mitigates impaired osteogenic differentiation and antioxidant response in D-galactose-induced senescent osteoblasts.
Li K, Huang K, Lu Q, Geng W, Jiang D, Guo A
European journal of pharmacology 2024 Sep 15;979:176849
European journal of pharmacology 2024 Sep 15;979:176849
BUB1 potentiates gastric cancer proliferation and metastasis by activating TRAF6/NF-κB/FGF18 through m6A modification.
Wang K, Shen K, Wang J, Yang K, Zhu J, Chen Y, Liu X, He Y, Zhu X, Zhan Q, Shi T, Li R
Life sciences 2024 Sep 15;353:122916
Life sciences 2024 Sep 15;353:122916
Radix Rehmanniae Praeparata promoted zebrafish fin regeneration through aryl hydrocarbon receptor-dependent autophagy.
Chen F, Pu S, Tian L, Zhang H, Zhou H, Yan Y, Hu X, Wu Q, Chen X, Cheng SH, Xu S
Journal of ethnopharmacology 2024 Sep 15;331:118272
Journal of ethnopharmacology 2024 Sep 15;331:118272
Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N(6)-methyladenosine (m(6)A) mediated silencing of SLC7A11.
Huang H, Lin Y, Xin J, Sun N, Zhao Z, Wang H, Duan L, Zhou Y, Liu X, Fang J, Jing B, Pan K, Zeng Y, Zeng D, Li H, Ma H, Bai Y, Wei L, Ni X
Ecotoxicology and environmental safety 2024 Sep 15;283:116816
Ecotoxicology and environmental safety 2024 Sep 15;283:116816
Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells via the IGF1R/AKT1/RHOA signaling pathway.
Yang J, Qin S, Sun N, Cai Y, Li J, Zhai Z, An J, Wang H, Du R, Qin J
Ecotoxicology and environmental safety 2024 Sep 15;283:116804
Ecotoxicology and environmental safety 2024 Sep 15;283:116804
Zinc oxide nanoparticles disrupt the mammary epithelial barrier via Z-DNA binding protein 1-triggered PANoptosis.
Zhu Z, Zhang Y, Wang R, Dong Y, Wu J, Shao L
Ecotoxicology and environmental safety 2024 Sep 15;283:116777
Ecotoxicology and environmental safety 2024 Sep 15;283:116777
Insufficient KIF15 during porcine oocyte ageing induces HDAC6-based microtubule instability.
Yin YX, Ding MQ, Yi Y, Zou YJ, Liao BY, Sun SC
Theriogenology 2024 Sep 15;226:49-56
Theriogenology 2024 Sep 15;226:49-56
Dissecting the role of SMN multimerization in its dissociation from the Cajal body using harmine as a tool compound.
Ohazama S, Fujimoto A, Konda D, Yokoyama R, Nakagawa S, Maita H
Journal of cell science 2024 Sep 15;137(18)
Journal of cell science 2024 Sep 15;137(18)
NSDHL promotes the degradation of sting in cholangiocarcinoma.
Yu W, Chen J, Tong Y, Zhu L, Deng Y, He J, Zhong C, Cai X
Heliyon 2024 Sep 15;10(17):e37592
Heliyon 2024 Sep 15;10(17):e37592
Huaier inhibits autophagy and promotes apoptosis in T-cell acute lymphoblastic leukemia by down-regulating SIRT1.
Qin X, Chen X, Wang F, Zhong F, Zeng Y, Liu W
Heliyon 2024 Sep 15;10(17):e37313
Heliyon 2024 Sep 15;10(17):e37313
Molecular basis of CX-5461-induced DNA damage response in primary vascular smooth muscle cells.
Liu T, Pan G, Zhang J, Wang J, Guo X, Chen Y, Wang X, Cui X, Liu H, Jiang F
Heliyon 2024 Sep 15;10(17):e37227
Heliyon 2024 Sep 15;10(17):e37227
C-di-GMP@ZIF-8 nanocomposite injectable hydrogel based on modified chitosan and hyaluronic acid for infected wound healing by activating STING signaling.
Ren H, Zhang J, Jiang Y, Hao S, You J, Yin Z
International journal of biological macromolecules 2024 Sep 14;280(Pt 1):135660
International journal of biological macromolecules 2024 Sep 14;280(Pt 1):135660
Ocotillol Derivatives Mitigate Retinal Ischemia-Reperfusion Injury by Regulating the Keap1/Nrf2/ARE Signaling Pathway.
Zhang X, Zhang W, Zhao L, Ma G, Huang Y, Geng Z, Jiang Q, Wen X, Lin Y, Meng Q, Zhang Z, Bi Y
Journal of medicinal chemistry 2024 Sep 12;67(17):15268-15290
Journal of medicinal chemistry 2024 Sep 12;67(17):15268-15290
DVL/GSK3/ISL1 pathway signaling: unraveling the mechanism of SIRT3 in neurogenesis and AD therapy.
Dai N, Su X, Li A, Li J, Jiang D, Wang Y
Stem cell research & therapy 2024 Sep 12;15(1):299
Stem cell research & therapy 2024 Sep 12;15(1):299
Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission.
Zhang L, Chen Y, Pan Q, Fang S, Zhang Z, Wang J, Yang Y, Yang D, Sun X
Acta biochimica et biophysica Sinica 2024 Sep 11;57(4):633-645
Acta biochimica et biophysica Sinica 2024 Sep 11;57(4):633-645
SQLE-a promising prognostic biomarker in cervical cancer: implications for tumor malignant behavior, cholesterol synthesis, epithelial-mesenchymal transition, and immune infiltration.
Zhao YC, Li YF, Qiu L, Jin SZ, Shen YN, Zhang CH, Cui J, Wang TJ
BMC cancer 2024 Sep 11;24(1):1133
BMC cancer 2024 Sep 11;24(1):1133
Single-cell RNA-seq analysis of rat molars reveals cell identity and driver genes associated with dental mesenchymal cell differentiation.
Zheng Y, Lu T, Zhang L, Gan Z, Li A, He C, He F, He S, Zhang J, Xiong F
BMC biology 2024 Sep 11;22(1):198
BMC biology 2024 Sep 11;22(1):198
Kidney targeting and modulating macrophage polarization through AMPK signaling: Therapeutic mechanism of berberine in uric acid nephropathy.
Gong S, Chen J, Zheng X, Lu X, Chen M, Li J, Su Z, Liu Y, Chen J, Xie J, Xie Q, Li Y
International immunopharmacology 2024 Sep 10;138:112632
International immunopharmacology 2024 Sep 10;138:112632
Downregulation of the (pro)renin receptor alleviates ferroptosis-associated cardiac pathological changes via the NCOA 4-mediated ferritinophagy pathway in diabetic cardiomyopathy.
Zhang X, Dong X, Jie H, Li S, Li H, Su Y, Li L, Kang L, Dong B, Zhang Y
International immunopharmacology 2024 Sep 10;138:112605
International immunopharmacology 2024 Sep 10;138:112605
Identification and validation of sialyltransferase ST3Gal5 in bladder cancer through bioinformatics and experimental analysis.
Jian Y, Chen Q, Al-Danakh A, Xu Z, Xu C, Sun X, Yu X, Yang D, Wang S
International immunopharmacology 2024 Sep 10;138:112569
International immunopharmacology 2024 Sep 10;138:112569
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization.
Yang R, Yang F, Wei Y, Huang B, Cao T, Tan H, Liu D, Zou Q, Wen J, Wen L, Lu X, Yu C, Cai H, Xie X, Jiang S, Yao S, Liang Y
International immunopharmacology 2024 Sep 10;138:112559
International immunopharmacology 2024 Sep 10;138:112559
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Wang Y, Chen SJ, Ma T, Long Q, Chen L, Xu KX, Cao Y
International immunopharmacology 2024 Sep 10;138:112517
International immunopharmacology 2024 Sep 10;138:112517
Endosialin-positive CAFs promote hepatocellular carcinoma progression by suppressing CD8(+) T cell infiltration.
Gan L, Lu T, Lu Y, Song H, Zhang J, Zhang K, Lu S, Wu X, Nie F, Di S, Han D, Yang F, Qin W, Wen W
Journal for immunotherapy of cancer 2024 Sep 10;12(9)
Journal for immunotherapy of cancer 2024 Sep 10;12(9)
MicroRNA-522-3p promotes brain metastasis in non-small cell lung cancer by targeting Tensin 1 and modulating blood-brain barrier permeability.
Liu Q, Bao H, Zhang S, Li C, Sun G, Sun X, Fu T, Wang Y, Liang P
Experimental cell research 2024 Sep 1;442(1):114199
Experimental cell research 2024 Sep 1;442(1):114199
Intervention of epithelial mesenchymal transition against colon cancer cell growth and metastasis based on SOX21/POU4F2/Hedgehog signaling axis.
Cao Q, Gao Y, Zhou C, Yan Y, Yu J, Wang P, Zhang B, Sun L
Life sciences 2024 Sep 1;352:122905
Life sciences 2024 Sep 1;352:122905
RNF31-mediated IKKα ubiquitination aggravates inflammation and intestinal injury through regulating NF-κB activation in human and mouse neonates.
Zhang Y, Tian Y, Zhong X, Zhang R, Yang S, Jin J, Lyu C, Fan J, Shi B, Zhu K, Xiao Y, Lin N, Ma D, Tou J, Shu Q, Lai D
Life sciences 2024 Sep 1;352:122893
Life sciences 2024 Sep 1;352:122893
Revitalizing gut barrier integrity: role of miR-192-5p in enhancing autophagy via Rictor in enteritis.
Qiu P, Zhou K, Wang Y, Chen X, Xiao C, Li W, Chen Y, Chang Y, Liu J, Zhou F, Wang X, Shang J, Liu L, Qiu Z
American journal of physiology. Gastrointestinal and liver physiology 2024 Sep 1;327(3):G317-G332
American journal of physiology. Gastrointestinal and liver physiology 2024 Sep 1;327(3):G317-G332
Network pharmacology prediction to discover the potential pharmacological action mechanism of Rhizoma Dioscoreae for liver regeneration.
Liu W, Wang W, Tian C, Sun MZ, Liu S, Liu Q
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Sep 1;28(5):479-491
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Sep 1;28(5):479-491
CXCR3 participates in asymmetric division of mouse oocytes by modulating actin dynamics.
Li WJ, Li RY, Wang DY, Shen M, Liu HL
Theriogenology 2024 Sep 1;225:43-54
Theriogenology 2024 Sep 1;225:43-54
Inhibition of 5-HT alleviates PTSD-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats.
Bai S, Ying ZM, Ying JK, Zhang QY, Lv YH, Wu ZM
Journal of neurophysiology 2024 Sep 1;132(3):979-990
Journal of neurophysiology 2024 Sep 1;132(3):979-990
The SARS-unique domain (SUD) of SARS-CoV-2 nsp3 protein inhibits the antiviral immune responses through the NF-κB pathway.
Xie S, Song Z, Chen R, Zhang X, Wu S, Chen J, Huang P, Liu H, Yu K, Zhang Y, Tan S, Liu J, Ma X, Zhang H, He X, Pan T
Journal of medical virology 2024 Oct;96(10):e70007
Journal of medical virology 2024 Oct;96(10):e70007
EIF4A3 is stabilized by the long noncoding RNA BC200 to regulate gene expression during Epstein-Barr virus infection.
Li J, Xin Y, Zhang S, Li Y, Jiang M, Zhang S, Yang L, Yang J, Cao P, Lu J
Journal of medical virology 2024 Oct;96(10):e29955
Journal of medical virology 2024 Oct;96(10):e29955
Rhein inhibits M1 polarization of BV2 microglia through MAPK/IκB signalling pathway and reduces neurotoxicity caused by neuroinflammation.
Qin X, Li B, Hu B, Huang J, Tian X, Zhang X, Wang Y, Huang W
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2024 Oct;84(6):533-545
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2024 Oct;84(6):533-545
RBM25 depletion suppresses the growth of colon cancer cells through regulating alternative splicing of MNK2.
Zhi L, Chen C, Zhang G, Huang T, He W, Zhang J, Chen D, Liu J, Zhao J, Qi Y, Wang G, Zhang W, Wang Y
Science China. Life sciences 2024 Oct;67(10):2186-2197
Science China. Life sciences 2024 Oct;67(10):2186-2197
YAP-LAMB3 axis dictates cellular resistance of pancreatic ductal adenocarcinoma cells to gemcitabine.
Li Y, Wang X, Yu H, Cao J, Xie J, Zhou J, Feng Z, Chen W
Molecular carcinogenesis 2024 Oct;63(10):1953-1966
Molecular carcinogenesis 2024 Oct;63(10):1953-1966
Role of NF-κB signaling pathway in H(2)O(2)-induced oxidative stress of hiPSCs.
Qin J, Yang J, Li J, Zhao D, An J, Zhai Z, Wang H, Li J, Dou M, Du R
In vitro cellular & developmental biology. Animal 2024 Oct;60(9):1021-1033
In vitro cellular & developmental biology. Animal 2024 Oct;60(9):1021-1033
Mechanism of Treadmill Exercise Combined with Rich Environmental Stimulation to Improve Depression in Post-stroke Depression Model Rats.
Lu L, Xu W, Feng L, Teng X, Ban W, Xue Y, Xing X, Zeng W, Li B
Actas espanolas de psiquiatria 2024 Oct;52(5):693-704
Actas espanolas de psiquiatria 2024 Oct;52(5):693-704
Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells.
Ren C, Wang Q, Fan S, Mi T, Zhang Z, He D
Inflammation 2024 Oct;47(5):1744-1761
Inflammation 2024 Oct;47(5):1744-1761
Ginseng polysaccharide promotes the apoptosis of colon cancer cells via activating the NLRP3 inflammasome.
Tian X, Zhang C, Wang D, Li X, Wang Q
Immunopharmacology and immunotoxicology 2024 Oct;46(5):715-726
Immunopharmacology and immunotoxicology 2024 Oct;46(5):715-726
A novel small-molecule PCSK9 inhibitor E28362 ameliorates hyperlipidemia and atherosclerosis.
Wang WZ, Liu C, Luo JQ, Lei LJ, Chen MH, Zhang YY, Sheng R, Li YN, Wang L, Jiang XH, Xiao TM, Zhang YH, Li SW, Wu YX, Xu Y, Xu YN, Si SY
Acta pharmacologica Sinica 2024 Oct;45(10):2119-2133
Acta pharmacologica Sinica 2024 Oct;45(10):2119-2133
Disordered regions in the IRE1α ER lumenal domain mediate its stress-induced clustering.
Kettel P, Marosits L, Spinetti E, Rechberger M, Giannini C, Radler P, Niedermoser I, Fischer I, Versteeg GA, Loose M, Covino R, Karagöz GE
The EMBO journal 2024 Oct;43(20):4668-4698
The EMBO journal 2024 Oct;43(20):4668-4698
Glycyrrhizin Protects Submandibular Gland Against Radiation Damage by Enhancing Antioxidant Defense and Preserving Mitochondrial Homeostasis.
Zhou XR, Wang XY, Sun YM, Zhang C, Liu KJ, Zhang FY, Xiang B
Antioxidants & redox signaling 2024 Oct;41(10-12):723-743
Antioxidants & redox signaling 2024 Oct;41(10-12):723-743
Identification of serum metabolites associated with aristolochic acid nephropathy severity and insights into the underlying mechanism.
Liu X, Peng Y, Wu S, Huang X, Gao L, Deng R, Lu J
Toxicology letters 2024 Oct;400:24-34
Toxicology letters 2024 Oct;400:24-34
Transcutaneous Auricular Vagus Nerve Stimulation Ameliorates Preeclampsia-Induced Apoptosis of Placental Trophoblastic Cells Via Inhibiting the Mitochondrial Unfolded Protein Response.
Zhao J, Yang Y, Qin J, Tao S, Jiang C, Huang H, Wan Q, Chen Y, Xu S, Qiao H
Neuroscience bulletin 2024 Oct;40(10):1502-1518
Neuroscience bulletin 2024 Oct;40(10):1502-1518
Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
Mo RL, Li Z, Zhang P, Sheng MH, Han GC, Sun DQ
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):8129-8143
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):8129-8143
Screening potential antileukemia agents from duckweed: Integration of chemical profiling, network pharmacology, and experimental validation.
Liu J, Huang M, Yang Y, Zeng Y, Yang Y, Guo Q, Liu W, Guo L
Phytochemical analysis : PCA 2024 Oct;35(7):1633-1648
Phytochemical analysis : PCA 2024 Oct;35(7):1633-1648
Fusobacterium nucleatum dysregulates inflammatory cytokines and NLRP3 inflammasomes in oral cells.
Sun J, Feng S, Ding T, Wang T, Du L, Kang W, Ge S
Oral diseases 2024 Oct;30(7):4767-4781
Oral diseases 2024 Oct;30(7):4767-4781
NAT10/CEBPB/vimentin signalling axis promotes adenoid cystic carcinoma malignant phenotypes in vitro.
Fu M, Gao Q, Xiao M, Sun XY, Li SL, Ge XY
Oral diseases 2024 Oct;30(7):4341-4355
Oral diseases 2024 Oct;30(7):4341-4355
METTL3 inhibitor STM2457 impairs tumor progression and enhances sensitivity to anlotinib in OSCC.
Liu L, Zhao T, Zheng S, Tang D, Han H, Yang C, Zheng X, Wang J, Ma J, Wei W, Wang Z, He S, He Q
Oral diseases 2024 Oct;30(7):4243-4254
Oral diseases 2024 Oct;30(7):4243-4254
GLS2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neurons.
Gao Y, Ma L, Yuan J, Huang Y, Ban Y, Zhang P, Tan D, Liang M, Li Z, Gong C, Xu T, Yang X, Chen Y
CNS neuroscience & therapeutics 2024 Oct;30(10):e70036
CNS neuroscience & therapeutics 2024 Oct;30(10):e70036
Neuron-specific deficiency of autophagy increases neuronal loss in traumatic brain injury.
Pei C, Li B, Wen S, Zhao K, Yu S, Li T, Li Y, Fu Y, Tian L, Xu H, Cheng H, Li R
PNAS nexus 2024 Oct;3(10):pgae457
PNAS nexus 2024 Oct;3(10):pgae457
Duck plague virus-encoded microRNA dev-miR-D28-3p inhibits viral replication via targeting UL27.
Ni H, Zhang X, Huang J, Wang M, Cheng A, Liu M, Zhu D, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Ou X, Sun D, Tian B, Jing B, Jia R
Veterinary microbiology 2024 Oct;297:110202
Veterinary microbiology 2024 Oct;297:110202
GDH1 exacerbates renal fibrosis by inhibiting the transcriptional activity of peroxisome proliferator-activated receptor gamma.
Qin J, Zhao Y, Li S, Liu Q, Huang S, Yu X
The FEBS journal 2024 Oct;291(20):4581-4601
The FEBS journal 2024 Oct;291(20):4581-4601
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
Shen Z, Zhao L, Yoo SA, Lin Z, Zhang Y, Yang W, Piao J
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
IRG1/Itaconate inhibits proliferation and promotes apoptosis of CD69(+)CD103(+)CD8(+) tissue-resident memory T cells in autoimmune hepatitis by regulating the JAK3/STAT3/P53 signalling pathway.
Zhou P, Tao K, Zeng L, Zeng X, Wan Y, Xie G, Liu X, Zhang P
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1738-1756
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1738-1756
2,5-Dihydroxyacetophenone attenuates acute kidney injury induced by intra-abdominal infection in rats.
Han T, Jiang Y, Ge W, Lu Y, Liu R, Sun Z
Nephrology (Carlton, Vic.) 2024 Oct;29(10):636-644
Nephrology (Carlton, Vic.) 2024 Oct;29(10):636-644
Lenvatinib acts on platelet‑derived growth factor receptor β to suppress the malignant behaviors of gastric cancer cells.
Tong X, Du J, Jiang Q, Wu Q, Zhao S, Chen S
Oncology letters 2024 Oct;28(4):483
Oncology letters 2024 Oct;28(4):483
Mitogen-activated protein kinase kinase kinase 1 facilitates the temozolomide resistance and migration of GBM via the MEK/ERK signalling.
Wu S, Xue S, Tang Y, Zhao W, Zheng M, Cheng Z, Hu X, Sun J, Ren J
Journal of cellular and molecular medicine 2024 Oct;28(20):e70173
Journal of cellular and molecular medicine 2024 Oct;28(20):e70173
Regulation of autophagy by ST3GAL2-mediated α2-3 sialylated glycosphingolipids in hepatic encephalopathy.
Li X, Xiao Y, Zhu Y, Li P, Zhou J, Yang J, Chen Z, Du H, Yu H, Guo Y, Bian H, Li Z
International journal of biological macromolecules 2024 Oct;278(Pt 4):135196
International journal of biological macromolecules 2024 Oct;278(Pt 4):135196
Identification of two novel B-cell epitopes located on the spike protein of swine acute diarrhea syndrome coronavirus.
Zhang L, Yang X, Shi H, Zhang J, Feng T, Liu D, Zhang X, Chen J, Shi D, Feng L
International journal of biological macromolecules 2024 Oct;278(Pt 4):135049
International journal of biological macromolecules 2024 Oct;278(Pt 4):135049
Human organic anion transporting polypeptide 1B3 (OATP1B3) is more heavily N-glycosylated than OATP1B1 in extracellular loops 2 and 5.
Liang T, Liu H, Li L, Huan R, Gui C
International journal of biological macromolecules 2024 Oct;278(Pt 2):134748
International journal of biological macromolecules 2024 Oct;278(Pt 2):134748
The suppression of OTUD7B by miR-491-5p enhances the ubiquitination of VEGFA to suppress vascular mimicry in non-small cell lung cancer.
Chen X, He L, Zhong H, Yan C, Ke B, Shi L
The journal of gene medicine 2024 Oct;26(10):e3743
The journal of gene medicine 2024 Oct;26(10):e3743
Exploring neuron-specific steroid synthesis and DHEAS therapy in Alzheimer's disease.
Lin HY, Feng YH, Kao TJ, Chen HC, Chen GY, Ko CY, Hsu TI
The Journal of steroid biochemistry and molecular biology 2024 Oct;243:106585
The Journal of steroid biochemistry and molecular biology 2024 Oct;243:106585
The LAMB3-EGFR signaling pathway mediates synergistic Anti-Cancer effects of berberine and emodin in Pancreatic cancer.
Xu C, Pascual-Sabater S, Fillat C, Goel A
Biochemical pharmacology 2024 Oct;228:116509
Biochemical pharmacology 2024 Oct;228:116509
Diarylpropionitrile-stimulated ERβ nuclear accumulation promotes MyoD-induced muscle regeneration in mdx mice by interacting with FOXO3A.
Tong H, Fan S, Hu W, Wang H, Guo G, Huang X, Zhao L, Li X, Zhang L, Jiang Z, Yu Q
Pharmacological research 2024 Oct;208:107376
Pharmacological research 2024 Oct;208:107376
LIM kinase 2 activates cardiac fibroblasts and exacerbates postinfarction left ventricular remodeling via crosstalk between the canonical and non-canonical Wnt pathways.
Gong C, Chang L, Huang R, Sun X, Liu Y, Wu S, Wang L, Xu B, Wang L
Pharmacological research 2024 Oct;208:107347
Pharmacological research 2024 Oct;208:107347
Oncoprotein-induced transcript 3 protein-enriched extracellular vesicles promotes NLRP3 ubiquitination to alleviate acute lung injury after cardiac surgery.
Li Y, Chen YT, Liu JS, Liang KF, Song YK, Cao Y, Chen CY, Jian YP, Liu XJ, Xu YQ, Yuan HX, Ou ZJ, Ou JS
Journal of molecular and cellular cardiology 2024 Oct;195:55-67
Journal of molecular and cellular cardiology 2024 Oct;195:55-67
Orthodontic tension promotes cementoblast mineralization by regulating autophagy.
Zhao Y, Yang Y, Liu H, Wang J, Huang Y, Li W
Journal of dental sciences 2024 Oct;19(4):2186-2195
Journal of dental sciences 2024 Oct;19(4):2186-2195
Targeting SOCS2 alleviates myocardial fibrosis by reducing nuclear translocation of β-catenin.
Yuan M, Shi H, Wang B, Cai J, Yu W, Wang W, Qian Q, Wang Y, Zhou X, Liu J
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119804
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119804
AMPK induces PIAS3 mediated SUMOylation of E3 ubiquitin ligase Smurf1 impairing osteogenic differentiation and traumatic heterotopic ossification.
Chen J, Dang YM, Liu MC, Gao L, Guan T, Hu A, Xiong L, Lin H
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119771
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119771
High-dose vitamin C attenuates radiation-induced pulmonary fibrosis by targeting S100A8 and S100A9.
Ma L, Jin Y, Aili A, Xu L, Wang X, Xiao L, Zhao W, Yin S, Liu B, Yuan X
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167358
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167358
Anti-CRMP2 antibody induces anxiety-like behavior and increases pyramidal neuron excitability in mice.
Pan Y, Jiang Y, Wang D, Guo Z, He F, Chen Z, Dai C, Yuan Z, Chen R, Xu K, Hu Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167338
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167338
Peroxiredoxin 4 deficiency induces accelerated ovarian aging through destroyed proteostasis in granulosa cells.
Zou X, Liang X, Dai W, Zhu T, Wang C, Zhou Y, Qian Y, Yan Z, Gao C, Gao L, Cui Y, Liu J, Meng Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167334
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167334
PPARγ/NF-κB axis contributes to cold-induced resolution of experimental colitis and preservation of intestinal barrier.
Di Y, Li H, Yang J, Feng M, Wang S, Li W, Wang X, Zhu Y, Shi Y, Feng R, Qu B
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167326
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167326
Ilexgenin A inhibits lipid accumulation in macrophages and reduces the progression of atherosclerosis through PTPN2/ERK1/2/ABCA1 signalling pathway.
Zhou Q, Wang Y, Cheng Y, Zhou J, Liu W, Ma X, Tang S, Tang S, Tang C
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Oct;1869(7):159533
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Oct;1869(7):159533
Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis.
Zhu J, Zhao H, Aierken A, Zhou T, Menggen M, Gao H, He R, Aimulajiang K, Wen H
PLoS neglected tropical diseases 2024 Oct;18(10):e0012587
PLoS neglected tropical diseases 2024 Oct;18(10):e0012587
Seno-antigen-pulsed dendritic cell vaccine induce anti-aging immunity to improve adipose tissue senescence and metabolic abnormalities.
Cao Y, Du X, Yu J, Wang Y, Jin X, Gu B, Yin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117433
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117433
Artemether ameliorates acetaminophen-induced liver injury through Nrf2 pathway.
Yu S, Yang N, Li H, Hu X, Zhang L, Li S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117280
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117280
Red nucleus mGluR2 but not mGluR3 mediates inhibitory effect in the development of SNI-induced neuropathological pain by suppressing the expressions of TNF-α and IL-1β.
Wang WT, Feng F, Zhang MM, Tian X, Yang QQ, Li YJ, Tao XX, Xu YL, Dou E, Wang JY, Zeng XY
Neurochemistry international 2024 Oct;179:105840
Neurochemistry international 2024 Oct;179:105840
Mechanisms of Shufeng Jiedu Capsule in treating bacterial pneumonia based on network pharmacology and experimental verification.
Xu Y, Bao L, Zhao R, Geng Z, Li S, Pang B, Sun Q, Guo S, Cui X, Sun J
Chinese herbal medicines 2024 Oct;16(4):656-666
Chinese herbal medicines 2024 Oct;16(4):656-666
Design, synthesis and biological evaluation of novel quinazoline-derived EGFR/HER-2 dual-target inhibitors bearing a heterocyclic-containing tail as potential anti-tumor agents.
Hao S, Wang JH, Hou L, Liang JW, Yan JH, Niu YF, Li XY, Sun Q, Meng FH
Bioorganic chemistry 2024 Oct;151:107686
Bioorganic chemistry 2024 Oct;151:107686
A rationally designed CD19 monoclonal antibody-triptolide conjugate for the treatment of systemic lupus erythematosus.
Wang L, Yin H, Jiang J, Li Q, Gao C, Li W, Zhang B, Xin Y, Li H, Zhao M, Lu Q
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4560-4576
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4560-4576
Xianling Lianxia formula improves the efficacy of trastuzumab by enhancing NK cell-mediated ADCC in HER2-positive BC.
Li F, Shi Y, Ma M, Yang X, Chen X, Xie Y, Liu S
Journal of pharmaceutical analysis 2024 Oct;14(10):100977
Journal of pharmaceutical analysis 2024 Oct;14(10):100977
Gui Qi Zhuang Jin Decoction ameliorates mitochondrial dysfunction in sarcopenia mice via AMPK/PGC-1α/Nrf2 axis revealed by a metabolomics approach.
Wang D, Qi W, Mao X, Zhang Y, Miao Z, Zhu C, Shao Y, Ge G, Zhang W, Jin H, Zhu H, Pan H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155908
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155908
Phenylpropanoid-rich maize root extract serves as a natural antidepressant.
Zhong T, Zhang Y, Yang H, Luo F, Xu Y, Fan Y, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155893
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155893
TRPM8 overexpression suppresses hepatocellular carcinoma progression and improves survival by modulating the RTP3/STAT3 pathway.
Chen L, Xu N, Gou D, Song J, Zhou M, Zhang Y, Zhang H, Zhu L, Huang W, Zhu Y, Gao C, Gu D, Xu Y, Zhou H
Cancer medicine 2024 Oct;13(19):e70109
Cancer medicine 2024 Oct;13(19):e70109
Chronic stress causes ovarian fibrosis to impair female fertility in mice.
Ma J, Wang L, Yang D, Luo J, Gao J, Wang J, Guo H, Li J, Wang F, Wu J, Hu R
Cellular signalling 2024 Oct;122:111334
Cellular signalling 2024 Oct;122:111334
YTHDF1 facilitates esophageal cancer progression via augmenting m6A-dependent TINAGL1 translation.
Zhang L, Cai E, Xu Y, Liu Z, Zheng M, Sun Z, Pei D, Wang Q
Cellular signalling 2024 Oct;122:111332
Cellular signalling 2024 Oct;122:111332
Exercise preconditioning mitigates brain injury after cerebral ischemia-reperfusion injury in rats by restraining TIMP1.
Meng X, Yang H, Chen F, Li B, Wu Y, Wang R
Immunity, inflammation and disease 2024 Oct;12(10):e70008
Immunity, inflammation and disease 2024 Oct;12(10):e70008
Oleanolic acid attenuates obesity through modulating the lipid metabolism in high-fat diet-fed mice.
Zhang G, Zhang H, Dong R, Zhao H, Li J, Yue W, Ma Z
Food science & nutrition 2024 Oct;12(10):8243-8254
Food science & nutrition 2024 Oct;12(10):8243-8254
Orientin promotes diabetic wounds healing by suppressing ferroptosis via activation of the Nrf2/GPX4 pathway.
Yang JY, Zhuang C, Lin YZ, Yu YT, Zhou CC, Zhang CY, Zhu ZT, Qian CJ, Zhou YN, Zheng WH, Zhao Y, Jin C, Wu ZY
Food science & nutrition 2024 Oct;12(10):7461-7480
Food science & nutrition 2024 Oct;12(10):7461-7480
NEMO-Binding Domain/IKKγ Inhibitory Peptide Alleviates Neuronal Pyroptosis in Spinal Cord Injury by Inhibiting ASMase-Induced Lysosome Membrane Permeabilization.
Geng Y, Lou J, Wu J, Tao Z, Yang N, Kuang J, Wu Y, Zhang J, Xiang L, Shi J, Cai Y, Wang X, Chen J, Xiao J, Zhou K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(40):e2405759
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(40):e2405759
LNMAC Promotes Cervical Squamous Cell Carcinoma Lymphatic Metastasis via Epigenetic Regulation of FGF2-Induced Lymphangiogenesis.
Zhang C, Yuan L, Wen W, Shao C, Liao Y, Jia Y, Zhao X, Liao Y, Xu D, Chen L, Yang G, Jiang H, Wang W, Yao S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2404645
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2404645
S100A2 activation promotes interstitial fibrosis in kidneys by FoxO1-mediated epithelial-mesenchymal transition.
Yang X, Zheng F, Yan P, Liu X, Chen X, Du X, Zhang Y, Wang P, Chen C, Lu H, Bai Y
Cell biology and toxicology 2024 Oct 9;40(1):86
Cell biology and toxicology 2024 Oct 9;40(1):86
EIF4A3-mediated oncogenic circRNA hsa_circ_0001165 advances esophageal squamous cell carcinoma progression through the miR-381-3p/TNS3 pathway.
Zhang X, Bian Y, Li Q, Yu C, Gao Y, Tian B, Xia W, Wang W, Xin L, Lin H, Wang L
Cell biology and toxicology 2024 Oct 9;40(1):84
Cell biology and toxicology 2024 Oct 9;40(1):84
Hypoxia-induced DTL promotes the proliferation, metastasis, and sorafenib resistance of hepatocellular carcinoma through ubiquitin-mediated degradation of SLTM and subsequent Notch pathway activation.
Chen ZX, Mu MY, Yang G, Qi H, Fu XB, Wang GS, Jiang WW, Huang BJ, Gao F
Cell death & disease 2024 Oct 9;15(10):734
Cell death & disease 2024 Oct 9;15(10):734
Astaxanthin Alleviates Chronic Prostatitis via the ERK1/2 Signaling Pathway: Evidence from Network Pharmacology and Experimental Validation.
Liu Y, Huang L, Zhang Z, Zhu Q, Xi P, Sun T, Gong B
Combinatorial chemistry & high throughput screening 2024 Oct 9;
Combinatorial chemistry & high throughput screening 2024 Oct 9;
Integrative bioinformatics analysis for identifying the mitochondrial-related gene signature associated with immune infiltration in premature ovarian insufficiency.
Lu M, Li W, Zhou J, Shang J, Lin L, Liu Y, Zhu X
BMC medicine 2024 Oct 8;22(1):444
BMC medicine 2024 Oct 8;22(1):444
Inhibition of HOXC11 by artesunate induces ferroptosis and suppresses ovarian cancer progression through transcriptional regulation of the PROM2/PI3K/AKT pathway.
Li J, Feng L, Yuan Y, He T, Zou X, Su B, Liu K, Yang X
World journal of surgical oncology 2024 Oct 8;22(1):268
World journal of surgical oncology 2024 Oct 8;22(1):268
Nme8 is essential for protection against chemotherapy drug cisplatin-induced male reproductive toxicity in mice.
Zhu H, Wang H, Wang D, Liu S, Sun X, Qu Z, Zhang A, Ye C, Li R, Wu B, Liu M, Gao J
Cell death & disease 2024 Oct 6;15(10):730
Cell death & disease 2024 Oct 6;15(10):730
Intracellular C5aR1 inhibits ferroptosis in glioblastoma through METTL3-dependent m6A methylation of GPX4.
Meng X, Wang Z, Yang Q, Liu Y, Gao Y, Chen H, Li A, Li R, Wang J, Sun G
Cell death & disease 2024 Oct 5;15(10):729
Cell death & disease 2024 Oct 5;15(10):729
YTHDF1-regulated ALOX5 in retinal pigment epithelial cells under hypoxia enhances VEGF expression and promotes viability, migration, and angiogenesis of vascular endothelial cells.
Dong Y, Qian C, Yan P, Wan G
Scientific reports 2024 Oct 5;14(1):23226
Scientific reports 2024 Oct 5;14(1):23226
Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Methylation in Protein Stability and Interaction.
Meng Y, Li Z, He M, Zhang Q, Deng Y, Wang Y, Huang R
Journal of proteome research 2024 Oct 4;23(10):4589-4600
Journal of proteome research 2024 Oct 4;23(10):4589-4600
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Niu R, Lan J, Liang D, Xiang L, Wu J, Zhang X, Li Z, Chen H, Geng L, Xu W, Gong S, Yang M
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.
Mao Y, Meng Y, Zou K, Qin N, Wang Y, Yan J, Chen P, Cheng Y, Shi W, Zhou C, Chen H, Sheng J, Liu X, Pan J, Huang H
Journal of neuroinflammation 2024 Oct 4;21(1):249
Journal of neuroinflammation 2024 Oct 4;21(1):249
Bile from the hemojuvelin-deficient mouse model of iron excess is enriched in iron and ferritin.
Prajapati M, Chiu L, Zhang JZ, Chong GS, DaSilva NA, Bartnikas TB
Metallomics : integrated biometal science 2024 Oct 4;16(10)
Metallomics : integrated biometal science 2024 Oct 4;16(10)
5-Hydroxymethylcytosine in circulating cell-free DNA as a potential diagnostic biomarker for SLE.
Tong X, Chen W, Ye L, Xiong Y, Xu Y, Luo Y, Xia X, Xu Z, Lin Y, Zhu X, Wang N, Xue X, Zhang H, Guo G
Lupus science & medicine 2024 Oct 4;11(2)
Lupus science & medicine 2024 Oct 4;11(2)
The transcription factor PPARA mediates SIRT1 regulation of NCOR1 to protect damaged heart cells.
Wang M, Zhou F, Luo Y, Deng X, Chen X, Yi Q
Cardiovascular diagnosis and therapy 2024 Oct 31;14(5):832-847
Cardiovascular diagnosis and therapy 2024 Oct 31;14(5):832-847
miR-744-5p promotes T-cell differentiation via inhibiting STK11.
Han J, Huang J, Hu J, Shi W, Wang H, Zhang W, Wang J, Shao H, Shen H, Bo H, Tao C, Wu F
Gene 2024 Oct 30;926:148635
Gene 2024 Oct 30;926:148635
Human adipose and umbilical cord mesenchymal stem cell-derived extracellular vesicles mitigate photoaging via TIMP1/Notch1.
Zhang H, Xiao X, Wang L, Shi X, Fu N, Wang S, Zhao RC
Signal transduction and targeted therapy 2024 Oct 30;9(1):294
Signal transduction and targeted therapy 2024 Oct 30;9(1):294
The RNA N6-methyladenosine demethylase FTO regulates ATG5 to inhibit malignant progression of uveal melanoma.
Yang Y, Zhong Y, Chi C, Lin X, Zhu X, Deng X, Liang J, Cheng Y
Journal of proteomics 2024 Oct 30;309:105282
Journal of proteomics 2024 Oct 30;309:105282
Filamin B knockdown impairs differentiation and function in mouse pre-osteoblasts via aberrant transcription and alternative splicing.
Wang X, Jia Q, Yu L, Huang J, Wang X, Zhou L, Mijiti W, Xie Z, Dong S, Xie Z, Ma H
Heliyon 2024 Oct 30;10(20):e39334
Heliyon 2024 Oct 30;10(20):e39334
Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role.
Anastasakis DG, Apostolidi M, Garman KA, Polash AH, Umar MI, Meng Q, Scutenaire J, Jarvis JE, Wang X, Haase AD, Brownell I, Rinehart J, Hafner M
Molecular cell 2024 Oct 3;84(19):3775-3789.e6
Molecular cell 2024 Oct 3;84(19):3775-3789.e6
Nuclear retention coupled with sequential polyadenylation dictates post-transcriptional m(6)A modification in the nucleus.
Tang P, Yang J, Chen Z, Du C, Yang Y, Zhao H, Huang L, Li G, Liu F, Dong B, Shan T, Bao X, Zhou Y
Molecular cell 2024 Oct 3;84(19):3758-3774.e10
Molecular cell 2024 Oct 3;84(19):3758-3774.e10
TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival.
Lascaux P, Hoslett G, Tribble S, Trugenberger C, Antičević I, Otten C, Torrecilla I, Koukouravas S, Zhao Y, Yang H, Aljarbou F, Ruggiano A, Song W, Peron C, Deangeli G, Domingo E, Bancroft J, Carrique L, Johnson E, Vendrell I, Fischer R, Ng AWT, Ngeow J, D'Angiolella V, Raimundo N, Maughan T, Popović M, Milošević I, Ramadan K
Cell 2024 Oct 3;187(20):5698-5718.e26
Cell 2024 Oct 3;187(20):5698-5718.e26
Schistosoma japonicum infection-mediated downregulation of lncRNA Malat1 contributes to schistosomiasis hepatic fibrosis by the Malat1/miR-96/Smad7 pathway.
Jiang P, Ye S, Fan X, Tian Y, Zhang D, Pan W
Parasites & vectors 2024 Oct 3;17(1):413
Parasites & vectors 2024 Oct 3;17(1):413
Mutation of Pseudomonas aeruginosa lasI/rhlI diminishes its cytotoxicity, oxidative stress, inflammation, and apoptosis on THP-1 macrophages.
Ren Y, You X, Zhu R, Li D, Wang C, He Z, Hu Y, Li Y, Liu X, Li Y
Microbiology spectrum 2024 Oct 3;12(10):e0414623
Microbiology spectrum 2024 Oct 3;12(10):e0414623
Antimicrobial efficiency and cytocompatibility of resveratrol and naringin as chemical decontaminants on SLA surface.
Zhou Y, Shen Z, Xu Y, Qian X-n, Chen W, Qiu J
Microbiology spectrum 2024 Oct 3;12(10):e0367923
Microbiology spectrum 2024 Oct 3;12(10):e0367923
Formononetin Mitigates Liver Fibrosis via Promoting Hepatic Stellate Cell Senescence and Inhibiting EZH2/YAP Axis.
Yuan Z, Meng J, Shen X, Wang M, Yu Y, Shi L, Li YL, Hassan HM, Li H, He ZX, Qin T
Journal of agricultural and food chemistry 2024 Oct 3;
Journal of agricultural and food chemistry 2024 Oct 3;
ML385, an Nrf2 Inhibitor, Synergically Enhanced Celastrol Triggered Endoplasmic Reticulum Stress in Lung Cancer Cells.
Xu C, Chen Y, Zhou Z, Yan Y, Fu W, Zou P, Ni D
ACS omega 2024 Oct 29;9(43):43697-43705
ACS omega 2024 Oct 29;9(43):43697-43705
HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway.
Liang Y, Lin H, Jiang Z, Zhao Q, Cui R, Li S
Discover oncology 2024 Oct 29;15(1):603
Discover oncology 2024 Oct 29;15(1):603
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
Chen Y, Chen W, Dai Y, Yan X, Jiang C, Zhang F, Zhang M, Hu X, Zhao J, Wu T, Li S, Han S, Chen X
Food & function 2024 Oct 28;15(21):10811-10822
Food & function 2024 Oct 28;15(21):10811-10822
CircCSPP1 Competitively Binds miR-10a to Regulate BMP7 Expression and Affects the Proliferation of Dermal Papilla Cells.
Lv X, Wang J, Xu Y, Zhou H, Li Y, Sun W
International journal of molecular sciences 2024 Oct 27;25(21)
International journal of molecular sciences 2024 Oct 27;25(21)
The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms.
Li Q, Liu Y, Zhi R, Wang Y
Discover oncology 2024 Oct 26;15(1):593
Discover oncology 2024 Oct 26;15(1):593
Sequential system based on ferritin delivery system and cell therapy for modulating the pathological microenvironment and promoting recovery.
Xu L, Yang J, Cao X, Chen J, Liu Z, Cai L, Yu Y, Huang H
International journal of pharmaceutics 2024 Oct 25;664:124607
International journal of pharmaceutics 2024 Oct 25;664:124607
Myrislignan ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Wang L, Fu X, Xia T, Yang Z, Zhao R
International immunopharmacology 2024 Oct 25;140:112887
International immunopharmacology 2024 Oct 25;140:112887
LncRNA MALAT1 regulates cigarette smoke induced airway inflammation by modulating miR-30a-5p/JNK signaling pathway.
Liu X, Ma Y, Zong D, Chen Y
International immunopharmacology 2024 Oct 25;140:112826
International immunopharmacology 2024 Oct 25;140:112826
SLC4A4 as a novel biomarker involved in immune system response and lung adenocarcinoma progression.
Quan S, Li N, Lian S, Wang Y, Liu Y, Liu J, Zhang Z, Gao D, Li Y
International immunopharmacology 2024 Oct 25;140:112756
International immunopharmacology 2024 Oct 25;140:112756
HIV Protein Nef Induces Cardiomyopathy Through Induction of Bcl2 and p21.
Kondrachuk O, Ciccone P, Ford N, Hong K, Kimura Y, Zi J, Yusuf S, Alkousa A, Tailor N, Rajkumar R, Rappaport J, Gupta MK
International journal of molecular sciences 2024 Oct 23;25(21)
International journal of molecular sciences 2024 Oct 23;25(21)
SETDB1 targeting SESN2 regulates mitochondrial damage and oxidative stress in renal ischemia-reperfusion injury.
Xia K, Hui Y, Zhang L, Qiu Q, Zhong J, Chen H, Liu X, Wang L, Chen Z
BMC biology 2024 Oct 23;22(1):246
BMC biology 2024 Oct 23;22(1):246
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Huang Y, Huang Y, Cai Z, Ferrari MW, Li C, Zhang T, Lyu G, Wang Z
Communications biology 2024 Oct 22;7(1):1371
Communications biology 2024 Oct 22;7(1):1371
Mitochondrial MOF regulates energy metabolism in heart failure via ATP5B hyperacetylation.
Hu Y, Zheng Y, Liu C, You Y, Wu Y, Wang P, Wu Y, Ba H, Lu J, Yuan Y, Liu P, Mao Y
Cell reports 2024 Oct 22;43(10):114839
Cell reports 2024 Oct 22;43(10):114839
Luteolin Protects against Vascular Calcification by Modulating SIRT1/CXCR4 Signaling Pathway and Promoting Autophagy.
Yu X, Xu L, Su C, Wang C, Wang Z, Wang Y, Lu X, Sun H
The AAPS journal 2024 Oct 22;26(6):111
The AAPS journal 2024 Oct 22;26(6):111
Nuclear receptor 4A1 ameliorates UUO-induced renal fibrosis by inhibiting the PI3K/AKT pathway.
Wang H, Wei Z, Xu C, Fang F, Wang Z, Zhong Y, Wang X
Scientific reports 2024 Oct 21;14(1):24787
Scientific reports 2024 Oct 21;14(1):24787
IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism.
Hornegger H, Anisimova AS, Muratovic A, Bourgeois B, Spinetti E, Niedermoser I, Covino R, Madl T, Karagöz GE
Nature communications 2024 Oct 20;15(1):9054
Nature communications 2024 Oct 20;15(1):9054
Targeting NUF2 suppresses gastric cancer progression through G2/M phase arrest and apoptosis induction.
Long B, Zhou H, Xiao L, Jiang X, Li J, Ma Z, He N, Xin W, Zhang B, Zhu X, Yu Z, Jiao Z
Chinese medical journal 2024 Oct 20;137(20):2437-2451
Chinese medical journal 2024 Oct 20;137(20):2437-2451
Sulforaphane Promotes Proliferation of Porcine Granulosa Cells via the H3K27ac-Mediated GDF8-ALK5-ERK Pathway.
Zhou J, Fu C, Shen M, Tao J, Liu H
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21635-21649
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21635-21649
The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals.
Li N, Yun B, Zeng L, Lv Y, Zhou Y, Fang M, Li S, Chen Y, Huang E, Zhang L, Jiang Y, Zhang H, Li J, Yuan X
Communications biology 2024 Oct 2;7(1):1246
Communications biology 2024 Oct 2;7(1):1246
Exploring the Mechanism of Sempervirine Inhibiting Glioblastoma Invasion Based on Network Pharmacology and Bioinformatics.
Zhang B, Wang W, Song Y, Chen H, Lin X, Chen J, Chen Y, Huang J, Li D, Wu S
Pharmaceuticals (Basel, Switzerland) 2024 Oct 2;17(10)
Pharmaceuticals (Basel, Switzerland) 2024 Oct 2;17(10)
Tumor Microenvironment-Responsive Biodegradable Nanomedicine for Self-Enhanced Synergistic Chemo-, Photothermal, and Chemodynamic Therapy.
Tang HX, He ZH, Liu CG, Zheng XK, Zhang ZJ
ACS applied materials & interfaces 2024 Oct 2;16(39):52023-52035
ACS applied materials & interfaces 2024 Oct 2;16(39):52023-52035
Lactobacillus rhamnosus GG-derived extracellular vesicles promote wound healing via miR-21-5p-mediated re-epithelization and angiogenesis.
Wang J, Li X, Zhao X, Yuan S, Dou H, Cheng T, Huang T, Lv Z, Tu Y, Shi Y, Ding X
Journal of nanobiotechnology 2024 Oct 19;22(1):644
Journal of nanobiotechnology 2024 Oct 19;22(1):644
A novel biomimetic nanovesicle containing caffeic acid-coupled carbon quantum dots for the the treatment of Alzheimer's disease via nasal administration.
Hu Y, Cui J, Sun J, Liu X, Gao S, Mei X, Wu C, Tian H
Journal of nanobiotechnology 2024 Oct 19;22(1):642
Journal of nanobiotechnology 2024 Oct 19;22(1):642
Platelet factors ameliorate thoracic aortic aneurysm and dissection by inhibiting the FGF-FGFR cascade activation in aortic-endothelial cell.
Wang J, He C, Chen Y, Hu X, Xu H, Liu J, Yang Y, Chen L, Li T, Fang L, Yang F, Li J, Luo J
iScience 2024 Oct 18;27(10):110953
iScience 2024 Oct 18;27(10):110953
Divergent input patterns to the central lateral amygdala play a duet in fear memory formation.
Gao JH, Liu YY, Xu HX, Wu K, Zhang LL, Cheng P, Peng XH, Cao JL, Hua R, Zhang YM
iScience 2024 Oct 18;27(10):110886
iScience 2024 Oct 18;27(10):110886
Quercetin alleviates liver fibrosis via regulating glycolysis of liver sinusoidal endothelial cells and neutrophil infiltration.
Chen X, Wang Y, Wan J, Dou X, Zhang C, Sun M, Ye F
Biomolecules & biomedicine 2024 Oct 17;24(6):1806-1815
Biomolecules & biomedicine 2024 Oct 17;24(6):1806-1815
GRASP55 Regulates Sorting and Maturation of the Lysosomal Enzyme β-Hexosaminidase A.
Akaaboune SR, Javed A, Bui S, Wierenga A, Wang Y
bioRxiv : the preprint server for biology 2024 Oct 17;
bioRxiv : the preprint server for biology 2024 Oct 17;
Expression study of Krabbe Disease GALC missense variants - Insights from quantification profiles of residual enzyme activity, secretion and psychosine levels.
Peng H, Lam YW, Zhou Z, Herdt AR, Gelb MH, Lee CW
bioRxiv : the preprint server for biology 2024 Oct 17;
bioRxiv : the preprint server for biology 2024 Oct 17;
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury.
Zhang Y, Li X, Dai Y, Han Y, Wei X, Wei G, Chen W, Kong S, He Y, Liu H, Ma N, Bin J, Tan N, He P, Liu Y
Journal of nanobiotechnology 2024 Oct 16;22(1):632
Journal of nanobiotechnology 2024 Oct 16;22(1):632
Seneca Valley virus circumvents Gasdermin A-mediated inflammation by targeting the pore-formation domain for cleavage.
Yin H, Zhao Z, Yan Y, Yuan Y, Qu W, Wang H, Zhu C, Li P, Li X
mBio 2024 Oct 16;15(10):e0168024
mBio 2024 Oct 16;15(10):e0168024
Micro RNA-175 Targets Claudin-1 to Inhibit Madin-Darby Canine Kidney Cell Adhesion.
Li X, Ma F, Wang S, Tang T, Ma L, Qiao Z, Ma Z, Wang J, Liu Z
Genes 2024 Oct 16;15(10)
Genes 2024 Oct 16;15(10)
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.
Wang S, Cheng T, Chen X, Zeng C, Qin W, Xu Y
Clinical science (London, England : 1979) 2024 Oct 16;138(20):1287-1304
Clinical science (London, England : 1979) 2024 Oct 16;138(20):1287-1304
The combination of paeoniflorin and metformin synergistically inhibits the progression of liver fibrosis in mice.
Meng L, Lv H, Kong Q, Li S, Jiang N, Yu C, Duan Z, Xiao Y, Liu Y
European journal of pharmacology 2024 Oct 15;981:176917
European journal of pharmacology 2024 Oct 15;981:176917
The Role of Human Adiponectin Receptor 1 in 2-Ethylhexyl Diphenyl Phosphate Induced Lipid Metabolic Disruption.
Feng J, Ma X, Liu Y, Shi X, Jin L, Le Y, Zhang Q, Wang C
Environmental science & technology 2024 Oct 15;58(41):18190-18201
Environmental science & technology 2024 Oct 15;58(41):18190-18201
Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma.
Guo S, Xing S, Wu Z, Chen F, Pan X, Li Q, Liu W, Zhang G
Cell reports. Medicine 2024 Oct 15;5(10):101753
Cell reports. Medicine 2024 Oct 15;5(10):101753
Human cytomegalovirus pUL135 protein affects endothelial cell function via CD2AP in Kawasaki disease.
Yu L, Li Y, Zhang Y, Weng L, Shuai D, Zhu J, Niu C, Chu M, Jia C
International journal of cardiology 2024 Oct 15;413:132364
International journal of cardiology 2024 Oct 15;413:132364
ARNTL2 facilitates bladder cancer progression through potentiating ENO1-mediated glycolysis in a SLC31A1-independent and -dependent manner.
Wang J, Ren J, Tu X, Yuan H, Ye Z, Wang X, Cui J, Wang J, Tang Y, Han P, Bai Y
Life sciences 2024 Oct 15;355:122974
Life sciences 2024 Oct 15;355:122974
Nanoparticles target M2 macrophages to silence kallikrein-related peptidase 12 for the treatment of tuberculosis and drug-resistant tuberculosis.
Wang Y, Liu Y, Long M, Dong Y, Li L, Zhou X
Acta biomaterialia 2024 Oct 15;188:358-373
Acta biomaterialia 2024 Oct 15;188:358-373
FPR1 signaling aberrantly regulates S100A8/A9 production by CD14(+)FCN1(hi) macrophages and aggravates pulmonary pathology in severe COVID-19.
Wang Z, Wang Y, Yan Q, Cai C, Feng Y, Huang Q, Li T, Yuan S, Huang J, Luo ZH, Zhou J
Communications biology 2024 Oct 14;7(1):1321
Communications biology 2024 Oct 14;7(1):1321
Neuronal BAG3 attenuates tau hyperphosphorylation, synaptic dysfunction, and cognitive deficits induced by traumatic brain injury via the regulation of autophagy-lysosome pathway.
Sweeney N, Kim TY, Morrison CT, Li L, Acosta D, Liang J, Datla NV, Fitzgerald JA, Huang H, Liu X, Tan GH, Wu M, Karelina K, Bray CE, Weil ZM, Scharre DW, Serrano GE, Saito T, Saido TC, Beach TG, Kokiko-Cochran ON, Godbout JP, Johnson GVW, Fu H
Acta neuropathologica 2024 Oct 11;148(1):52
Acta neuropathologica 2024 Oct 11;148(1):52
Ursodeoxycholic Acid Platinum(IV) Conjugates as Antiproliferative and Antimetastatic Agents: Remodel the Tumor Microenvironment through Suppressing JAK2/STAT3 Signaling.
Chen Y, Zhang M, Liu Z, Zhang N, Wang Q
Journal of medicinal chemistry 2024 Oct 10;67(19):17551-17567
Journal of medicinal chemistry 2024 Oct 10;67(19):17551-17567
SMEK1 promotes clear cell renal cell carcinoma progression via EGFR tyrosine-kinase dependent pathway.
Wang J, Bi W, Lv R, Wang Z, Xin Q, Li K, Chen Y, Liu Q, Zhang X
Cancer letters 2024 Oct 1;601:217148
Cancer letters 2024 Oct 1;601:217148
Vitexin Inhibits TNBC Progression and Metastasis by Modulating Macrophage Polarization Through EGFR Signaling.
Lin Y, Li L, Huang H, Wen X, Zhang Y, Zhang R, Huang W
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Oct 1;47(8):303-312
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Oct 1;47(8):303-312
SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8(+) T cell activation.
Liu W, You D, Lin J, Zou H, Zhang L, Luo S, Yuan Y, Wang Z, Qi J, Wang W, Ye X, Yang X, Deng Y, Teng F, Zheng X, Lin Y, Huang Z, Huang Y, Yang Z, Zhou X, Zhang Y, Chen R, Xu L, Li J, Yang W, Zhang H
Cell metabolism 2024 Oct 1;36(10):2245-2261.e6
Cell metabolism 2024 Oct 1;36(10):2245-2261.e6
Chronic exposure to polystyrene microplastics induced LHR reduction and decreased testosterone levels through NF-κB pathway.
Jin H, Ding J, Liu H, Yang L, Li D, Han X
Environmental pollution (Barking, Essex : 1987) 2024 Oct 1;358:124543
Environmental pollution (Barking, Essex : 1987) 2024 Oct 1;358:124543
FBXL19 in endothelial cells protects the heart from influenza A infection by enhancing antiviral immunity and reducing cellular senescence programs.
Xia B, Chen H, Taleb SJ, Xi X, Shaheen N, Baoyinna B, Soni S, Mebratu YA, Yount JS, Zhao J, Zhao Y
American journal of physiology. Heart and circulatory physiology 2024 Oct 1;327(4):H937-H946
American journal of physiology. Heart and circulatory physiology 2024 Oct 1;327(4):H937-H946
The phosphorylation of Smad3 by CaMKIIγ leads to the hepatocyte pyroptosis under perfluorooctane sulfonate exposure.
Ren S, Liang P, Feng R, Yang W, Qiu T, Zhang J, Li Q, Yang G, Sun X, Yao X
Ecotoxicology and environmental safety 2024 Oct 1;284:116924
Ecotoxicology and environmental safety 2024 Oct 1;284:116924
Modulation of choline and lactate metabolism by basic fibroblast growth factor mitigates neuroinflammation in type 2 diabetes: Insights from (1)H-NMR metabolomics analysis.
Wu Y, Wang X, Zhang W, Fu J, Jiang K, Shen Y, Li C, Gao H
Neuropharmacology 2024 Oct 1;257:110049
Neuropharmacology 2024 Oct 1;257:110049
Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways.
Li J, Zhang SX, Wang DL, Qi JJ, Bai CY, Sun H, Sun BX, Liang S
Theriogenology 2024 Oct 1;227:1-8
Theriogenology 2024 Oct 1;227:1-8
Induction of tau pathology and motor dysfunction in mice by urinary exosomes from progressive supranuclear palsy patients.
Li Q, Liu H, Zhu Q, Zhang R, Liang D, Zhang J, Jin R, Chen Y, Qin C, Teng J
Brain research bulletin 2024 Oct 1;216:111046
Brain research bulletin 2024 Oct 1;216:111046
Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins.
Ma D, Xie A, Lv J, Min X, Zhang X, Zhou Q, Gao D, Wang E, Gao L, Cheng L, Liu S
Protein & cell 2024 Oct 1;15(10):724-743
Protein & cell 2024 Oct 1;15(10):724-743
KLF2 Inhibits Ferroptosis and Improves Mitochondrial Dysfunction in Chondrocyte Through SIRT1/GPX4 Signaling to Improve Osteoarthritis.
Shi J, Chen L, Wang X, Ma X
Drug development research 2024 Nov;85(7):e70015
Drug development research 2024 Nov;85(7):e70015
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Lan X, Wang Q, Liu Y, You Q, Wei W, Zhu C, Hai D, Cai Z, Yu J, Zhang J, Liu N
Redox biology 2024 Nov;77:103406
Redox biology 2024 Nov;77:103406
PPARγ-mediated amelioration of lipid metabolism abnormality by kaempferol.
Xue P, You X, Ren L, Yue W, Ma Z
Archives of biochemistry and biophysics 2024 Nov;761:110154
Archives of biochemistry and biophysics 2024 Nov;761:110154
Serum exosomal miRNA promote glioma progression by targeting SOS1 via abscopal effect of radiation.
Zhang Y, Xie J, Zhang H, Li J, Mi X, Zhou X, Ding Z
Archives of biochemistry and biophysics 2024 Nov;761:110138
Archives of biochemistry and biophysics 2024 Nov;761:110138
Downregulation of C1R promotes hepatocellular carcinoma development by activating HIF-1α-regulated glycolysis.
Ma Y, Wang Y, Tuo P, Meng Z, Jiang B, Yuan Y, Ding Y, Naeem A, Guo X, Wang X
Molecular carcinogenesis 2024 Nov;63(11):2237-2253
Molecular carcinogenesis 2024 Nov;63(11):2237-2253
Combined treatment with Aronia berry extract and oligomeric proanthocyanidins exhibit a synergistic anticancer efficacy through LMNB1-AKT signaling pathways in colorectal cancer.
Li Y, Xu C, Weng W, Goel A
Molecular carcinogenesis 2024 Nov;63(11):2145-2157
Molecular carcinogenesis 2024 Nov;63(11):2145-2157
Non-coding RNA alterations in occlusal disharmony-induced anxiety-like behaviour.
Zhang M, Wu L, Zhang S, Li Y, Chen J
Journal of oral rehabilitation 2024 Nov;51(11):2248-2260
Journal of oral rehabilitation 2024 Nov;51(11):2248-2260
Sappanone A ameliorates acute lung injury through inhibiting the activation of the NF-κB signaling pathway.
Du J, Zhou P, Zhao X, He YT, He CS, Wang RY
Toxicology and applied pharmacology 2024 Nov;492:117127
Toxicology and applied pharmacology 2024 Nov;492:117127
CD73 alleviates osteoarthritis by maintaining anabolism and suppressing catabolism of chondrocytes extracellular matrix.
Guo H, Lv Z, Wang M, Li W, Xie Y, Liu Z, Chen F, Jiang R, Liu Y, Wu R, Li J, Sun Z, Tan G, Shi D
Journal of orthopaedic translation 2024 Nov;49:96-106
Journal of orthopaedic translation 2024 Nov;49:96-106
SUGT1 regulates the progression of ovarian cancer through the AKT/PI3K/mTOR signaling pathway.
Ke M, Xu J, Ouyang Y, Chen J, Yuan D, Guo T
Translational oncology 2024 Nov;49:102088
Translational oncology 2024 Nov;49:102088
MDM2 accelerated renal senescence via ubiquitination and degradation of HDAC1.
Xiang HL, Yuan Q, Zeng JY, Xu ZY, Zhang HZ, Huang J, Song AN, Xiong J, Zhang C
Acta pharmacologica Sinica 2024 Nov;45(11):2328-2338
Acta pharmacologica Sinica 2024 Nov;45(11):2328-2338
Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E-deficient mice.
Xu MY, Xu JJ, Kang LJ, Liu ZH, Su MM, Zhao WQ, Wang ZH, Sun L, Xiao JB, Evans PC, Tian XY, Wang L, Huang Y, Liang XM, Weng JP, Xu SW
Acta pharmacologica Sinica 2024 Nov;45(11):2277-2289
Acta pharmacologica Sinica 2024 Nov;45(11):2277-2289
CypA/TAF15/STAT5A/miR-514a-3p feedback loop drives ovarian cancer metastasis.
Li Y, Yang H, Li A, Chen B, Wang Y, Song Z, Tan H, Li H, Feng Q, Zhou Y, Li S, Zeng L, Lan T
Oncogene 2024 Nov;43(49):3570-3585
Oncogene 2024 Nov;43(49):3570-3585
O-GlcNAcylation of circadian clock protein Bmal1 impairs cognitive function in diabetic mice.
Hui Y, Zhong Y, Kuang L, Xu J, Hao Y, Cao J, Zheng T
The EMBO journal 2024 Nov;43(22):5667-5689
The EMBO journal 2024 Nov;43(22):5667-5689
PCPE-1, a brown adipose tissue-derived cytokine, promotes obesity-induced liver fibrosis.
Hsiao YT, Yoshida Y, Okuda S, Abe M, Mizuno S, Takahashi S, Nakagami H, Morishita R, Kamimura K, Terai S, Aung TM, Li J, Furihata T, Tang JY, Walsh K, Ishigami A, Minamino T, Shimizu I
The EMBO journal 2024 Nov;43(21):4846-4869
The EMBO journal 2024 Nov;43(21):4846-4869
OSGIN1 regulates PM(2.5)-induced fibrosis via mediating autophagy in an in vitro model of COPD.
Tang X, Zhu H, Zhou M, Zhang H, Xiao Q, Yuan Q, Sun G, Zhang Z, Chu H
Toxicology letters 2024 Nov;401:35-43
Toxicology letters 2024 Nov;401:35-43
LncRNA MBNL1-AS1 knockdown increases the sensitivity of hepatocellular carcinoma to tripterine by regulating miR-708-5p-mediated glycolysis.
Zhang H, Zhao L, Ren P, Sun X
Biotechnology & genetic engineering reviews 2024 Nov;40(3):1407-1424
Biotechnology & genetic engineering reviews 2024 Nov;40(3):1407-1424
Long non-coding RNA MALAT1 triggers ferroptosis via interaction with FUS to enhance ACSF2 mRNA stabilization in septic acute kidney injury.
Duan ZB, Zheng JF, Huang SY, Hu LL
The Kaohsiung journal of medical sciences 2024 Nov;40(11):972-984
The Kaohsiung journal of medical sciences 2024 Nov;40(11):972-984
Ferulic Acid Inhibits Arsenic-Induced Colon Injury by Improving Intestinal Barrier Function.
Wang S, Hong Y, Li Y, Zhang Z, Han J, Yang Z, Yang Y, Ma Z, Wang Q
Environmental toxicology 2024 Nov;39(11):4821-4831
Environmental toxicology 2024 Nov;39(11):4821-4831
Geniposidic Acid Attenuates Chronic Tubulointerstitial Nephropathy Through Regulation of the NF-ƙB/Nrf2 Pathway Via Aryl Hydrocarbon Receptor Signaling.
Wang YN, Li XJ, Wang WF, Zou L, Miao H, Zhao YY
Phytotherapy research : PTR 2024 Nov;38(11):5441-5457
Phytotherapy research : PTR 2024 Nov;38(11):5441-5457
Albumin-based co-loaded sonosensitizer and STING agonist nanodelivery system for enhanced sonodynamic and immune combination antitumor therapy.
Huang H, Du L, Su R, Li Z, Shao Y, Yuan Y, Wang C, Lu C, He Y, He H, Zhang C
Journal of controlled release : official journal of the Controlled Release Society 2024 Nov;375:524-536
Journal of controlled release : official journal of the Controlled Release Society 2024 Nov;375:524-536
LNP-mRNA vaccine prevents type 1 diabetes in non-obese diabetes mice.
Chen J, Hu Y, Chen Y, Zhou Z, Shen Y, Wang Y, Liu Z, Li X, Su Z, Wu J
Journal of controlled release : official journal of the Controlled Release Society 2024 Nov;375:513-523
Journal of controlled release : official journal of the Controlled Release Society 2024 Nov;375:513-523
Exosomal miR-129-2-3p promotes airway epithelial barrier disruption in PM(2.5)-aggravated asthma.
Wang C, Niu Z, Zhang Y, Liu N, Ji X, Tian J, Guan L, Shi D, Zheng H, Gao Y, Zhao L, Zhang W, Zhang Z
Journal of environmental management 2024 Nov;370:123053
Journal of environmental management 2024 Nov;370:123053
NLRP12 inhibits PRRSV-2 replication by promoting GP2a degradation via MARCH8.
Jing H, Song Y, Duan E, Liu J, Ke W, Tao R, Lv Y, Zhao P, Dong W, Li X, Guo Y, Li H
Veterinary microbiology 2024 Nov;298:110271
Veterinary microbiology 2024 Nov;298:110271
NFκB dynamics-dependent epigenetic changes modulate inflammatory gene expression and induce cellular senescence.
Tabata S, Matsuda K, Soeda S, Nagai K, Izumi Y, Takahashi M, Motomura Y, Ichikawa Nagasato A, Moro K, Bamba T, Okada M
The FEBS journal 2024 Nov;291(22):4951-4968
The FEBS journal 2024 Nov;291(22):4951-4968
Integration of pharmacochemistry, pharmacodynamics and metabolomics to reveal active ingredients and mechanism of Nan Bao detox capsule alleviating methamphetamine addiction.
Zhang B, Yang C, Zheng Y, Li X, Wang X, Yuehui L
Addiction biology 2024 Nov;29(11):e70005
Addiction biology 2024 Nov;29(11):e70005
Methacrylated hyaluronic acid/laponite photosensitive, sustained-release hydrogel loaded with bilobalide for enhancing random flap survival through mitigation of endoplasmic reticulum stress.
Ye J, Yin X, Xie S, Hua Q, Zhu J, Chen J, Zheng W, Cai L
International journal of biological macromolecules 2024 Nov;281(Pt 1):136277
International journal of biological macromolecules 2024 Nov;281(Pt 1):136277
Ciclopirox platinum(IV) conjugates suppress tumors by promoting mitophagy and provoking immune responses.
Li S, Feng S, Chen Y, Sun B, Zhang N, Zhao Y, Han J, Liu Z, He YQ, Wang Q
Journal of inorganic biochemistry 2024 Nov;260:112696
Journal of inorganic biochemistry 2024 Nov;260:112696
CYR61/CCN1: A novel mediator of redox response in corneal stromal cells of keratoconus.
Liu X, Zhang X, Li Q, Wei C, Guo X, Zhao L, Liu T, Bao Q, Dou S, Seitz B, Hua G
Experimental eye research 2024 Nov;248:110093
Experimental eye research 2024 Nov;248:110093
Mechanistic study of NUPR1 in bladder cancer development through transcriptional regulation of CCR2.
Shi Z, Mi Y, Zhang L, Zhang W, Zhang W, Shi X, Gao S, Zuo L, Zhang L
Journal of cellular physiology 2024 Nov;239(11):e31412
Journal of cellular physiology 2024 Nov;239(11):e31412
Novel intercellular spread mode of respiratory syncytial virus contributes to neutralization escape.
Zhang W, Lin X, Li ZY, Zhang LJ, Chen L, Sun YP, Si JY, Zhao M, Wu GH, Zhan LT, Yang KY, You RL, Wang YB, Xia NS, Zheng ZZ
Antiviral research 2024 Nov;231:106023
Antiviral research 2024 Nov;231:106023
Novel deoxyhypusine synthase (DHPS) inhibitors target hypusination-induced vasculogenic mimicry (VM) against malignant melanoma.
Zhao XH, Ma J, Guo JS, Liu KL, Qin YX, Li LT, Zhang JF, Yang YY, Zhang SC, Meng FH, Liu L, Yang YH, Li XY
Pharmacological research 2024 Nov;209:107453
Pharmacological research 2024 Nov;209:107453
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca(2+) and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy.
Jiang L, He H, Tang Y, Li J, Reilly S, Xin H, Li Z, Cai H, Zhang X
Autophagy 2024 Nov;20(11):2388-2404
Autophagy 2024 Nov;20(11):2388-2404
Mechanism of Gastrodin against neurotoxicity based on network pharmacology, molecular docking and experimental verification.
Guo H, Li C, Zhao J, Guo T, Chen S, Qin X, Zhu K, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117611
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117611
Oleocanthal mitigates CoCl(2)-induced oxidative damage and apoptosis via regulating MAPK pathway in human retinal pigment epithelial cells.
Huang KC, Chiang YF, Ali M, Hsia SM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117582
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117582
Simeprevir induces ferroptosis through β-TrCP/Nrf2/GPX4 axis in triple-negative breast cancer cells.
Lin Z, Liu Z, Yang X, Pan Z, Feng Y, Zhang Y, Chen H, Lao L, Chen J, Shi F, Gong C, Zeng W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117558
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117558
Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy.
Liu P, Wu X, Lv H, Huang J, Gu T, Liu D, Xu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117547
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117547
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Lu Q, Ma J, Zhao Y, Ding G, Wang Y, Qiao X, Cheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
6-Gingerol improves lipid metabolism disorders in skeletal muscle by regulating AdipoR1/AMPK signaling pathway.
Peng Z, Zeng Y, Zeng X, Tan Q, He Q, Wang S, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117462
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117462
Apelin regulates mitochondrial dynamics by inhibiting Mst1-JNK-Drp1 signaling pathway to reduce neuronal apoptosis after spinal cord injury.
Guo Q, Liu Q, Zhou S, Lin Y, Lv A, Zhang L, Li L, Huang F
Neurochemistry international 2024 Nov;180:105885
Neurochemistry international 2024 Nov;180:105885
Shh regulates M2 microglial polarization and fibrotic scar formation after ischemic stroke.
Yang Q, Jiang P, Tang H, Wen J, Zhou L, Zhao Y, Wang L, Wang J, Yang Q
Neurochemistry international 2024 Nov;180:105862
Neurochemistry international 2024 Nov;180:105862
Alteration of N-glycosylation of CDON promotes H(2)O(2)-induced DNA damage in H9c2 cardiomyocytes.
Chen L, Liu H, Zhan W, Long C, Xu F, Li X, Tian XL, Chen S
The international journal of biochemistry & cell biology 2024 Nov;176:106671
The international journal of biochemistry & cell biology 2024 Nov;176:106671
Involvement of spinal NADPH oxidase 4 and endoplasmic reticulum stress in morphine-tolerant rats.
Xiao X, Yang J, Bai Q, Wang Z, Chen Y, Si Y, Xu Y, Li Z, Bu H
Journal of neurochemistry 2024 Nov;168(11):3745-3759
Journal of neurochemistry 2024 Nov;168(11):3745-3759
Immunoinhibitory effects of hypoxia-driven reprogramming of EGR1(hi) and EGR3 positive B cells in the nasopharyngeal carcinoma microenvironment.
Ge Y, Liu H, Huang W, Zhu H, Zong D, He X
Oral oncology 2024 Nov;158:106999
Oral oncology 2024 Nov;158:106999
Selenomethionine alleviates Aeromonas hydrophila-induced oxidative stress and ferroptosis via the Nrf2/HO1/GPX4 pathway in grass carp.
Yu P, Su L, Li B, Su J, Yuan G
Fish & shellfish immunology 2024 Nov;154:109927
Fish & shellfish immunology 2024 Nov;154:109927
ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification.
Wang Q, Zeng S, Liang Y, Zhou R, Wang D
The Journal of investigative dermatology 2024 Nov;144(11):2406-2416.e10
The Journal of investigative dermatology 2024 Nov;144(11):2406-2416.e10
Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats.
Zhu J, Lin Y, Li G, He Y, Su Z, Tang Y, Zhang Y, Xu Q, Yao Z, Zhou H, Liu B, Cai X
Journal of pharmaceutical analysis 2024 Nov;14(11):100981
Journal of pharmaceutical analysis 2024 Nov;14(11):100981
Ligustilide alleviates oxidative stress during renal ischemia-reperfusion injury through maintaining Sirt3-dependent mitochondrial homeostasis.
Xia K, Jin Z, Qiu Q, Zhou Y, Lu Y, Qiu T, Zhou J, Chen Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155975
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155975
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Feng YL, Xu XR, Zhu QM, Chang J, Zhang HL, Wang N, Sun JB, Liu J, Zhang J, Sun CP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Copper-Based Composites Nanoparticles Improve Triple-Negative Breast Cancer Treatment with Induction of Apoptosis-Cuproptosis and Immune Activation.
Wang N, Liu Y, Peng D, Zhang Q, Zhang Z, Xu L, Yin L, Zhao X, Lu Z, Peng J
Advanced healthcare materials 2024 Nov;13(28):e2401646
Advanced healthcare materials 2024 Nov;13(28):e2401646
Dual-Barb Microneedle with JAK/STAT Inhibitor-Loaded Nanovesicles Encapsulation for Tendinopathy.
Chen M, Zou F, Wang P, Hu W, Shen P, Wu X, Xu H, Rui Y, Wang X, Wang Y
Advanced healthcare materials 2024 Nov;13(28):e2401512
Advanced healthcare materials 2024 Nov;13(28):e2401512
Mn(II)-Aloe-Emodin Nanoscale Coordination Polymer Enhances Ferroptosis by Synergistically Enhancing Reactive Oxygen Species Generation via the Nrf2-GPX4 Axis.
Yang X, Li C, Ge M, Li X, Zhao W, Guo H, Nie H, Liu J
Advanced healthcare materials 2024 Nov;13(28):e2400474
Advanced healthcare materials 2024 Nov;13(28):e2400474
CaMKII Exacerbates Doxorubicin-Induced Cardiotoxicity by Promoting Ubiquitination Through USP10 Inhibition.
Yang Y, Wang Z, Wang N, Yang J, Yang L
Cancer medicine 2024 Nov;13(21):e70286
Cancer medicine 2024 Nov;13(21):e70286
Erbin alleviates sepsis-induced cardiomyopathy by inhibiting RIPK1-dependent necroptosis through activating PKA/CREB pathway.
Zhou H, Gong H, Liu H, Jing G, Xia Y, Wang Y, Wu D, Yang C, Zuo J, Wang Y, Wu X, Song X
Cellular signalling 2024 Nov;123:111374
Cellular signalling 2024 Nov;123:111374
LncRNA H19 accelerates renal fibrosis by negatively regulating the let-7b-5p/TGF-βR1/COL1A1 axis.
Li HY, Xu XY, Lv SH, Chen W, Wang Y, Fu Y, Yang JP
Cellular signalling 2024 Nov;123:111373
Cellular signalling 2024 Nov;123:111373
Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1.
Ke B, Huang Y, Gong Y, Zhong H, Shi L
Cellular signalling 2024 Nov;123:111357
Cellular signalling 2024 Nov;123:111357
Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway.
Mao Y, Liu P, Wei J, Xie Y, Zheng Q, Hu X, Yao J, Meng W
Journal of translational internal medicine 2024 Nov;12(5):478-494
Journal of translational internal medicine 2024 Nov;12(5):478-494
LncRNA FAISL Inhibits Calpain 2-Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast Cancer.
Zhang Y, Wei S, Chen Z, Xu R, Li SR, You L, Wu R, Zhang Y, Liao JY, Xu X, Song E, Luo ML
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2407493
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2407493
A Multi-Functional Nanoadjuvant Coupling Manganese with Toll-Like 9 Agonist Stimulates Potent Innate and Adaptive Anti-Tumor Immunity.
Liu Z, Li S, Xiao Y, Liu X, Zhang B, Zeng Q, Ao Q, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2402678
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2402678
Role of PI3K/AKT signaling pathway involved in self-renewing and maintaining biological properties of chicken primordial germ cells.
Liu X, Ye L, Ding Y, Gong W, Qian H, Jin K, Niu Y, Zuo Q, Song J, Han W, Chen G, Li B
Poultry science 2024 Nov;103(11):104140
Poultry science 2024 Nov;103(11):104140
Host-specific SRSF7 regulates polymerase activity and replication of influenza A virus.
Zhao L, Li S, Deng L, Zhang Y, Jiang C, Wei Y, Xia J, Ping J
Microbes and infection 2024 Nov-Dec;26(8):105401
Microbes and infection 2024 Nov-Dec;26(8):105401
Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway.
Lin Y, Huang Y, Zheng Y, Chen W, Zhang Y, Yang Y, Huang W
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Nov-Dec 01;47(9):369-377
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Nov-Dec 01;47(9):369-377
Dapagliflozin targets SGLT2/SIRT1 signaling to attenuate the osteogenic transdifferentiation of vascular smooth muscle cells.
Li L, Liu H, Chai Q, Wei J, Qin Y, Yang J, Liu H, Qi J, Guo C, Lu Z
Cellular and molecular life sciences : CMLS 2024 Nov 9;81(1):448
Cellular and molecular life sciences : CMLS 2024 Nov 9;81(1):448
GPR30 Agonist G1 Mitigates Sepsis-Induced Cardiac Dysfunction by Inhibiting ACE2/c-FOS-Mediated Necroptosis in Female Mice.
Wang X, Wang X, Ma J, Zhang S, Fang W, Xu F, Du J, Liang H, Duan W, Li Z, Liu J
ACS infectious diseases 2024 Nov 8;10(11):3797-3809
ACS infectious diseases 2024 Nov 8;10(11):3797-3809
N-acetylglucosaminyltransferase V drives colorectal cancer metastasis by facilitating ZO-1 ubiquitination and degradation.
Zhan Y, Huang C, Wang R, Xiao X, Xu X, Gao C
Cancer cell international 2024 Nov 7;24(1):366
Cancer cell international 2024 Nov 7;24(1):366
NEK2 is a potential pan-cancer biomarker and immunotherapy target.
Zhang L, Li Y, Deng J, Liao W, Liu T, Shen F
Discover oncology 2024 Nov 7;15(1):626
Discover oncology 2024 Nov 7;15(1):626
Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.
Zhou X, Zhang L, Aryal S, Veasey V, Tajik A, Restelli C, Moreira S, Zhang P, Zhang Y, Hope KJ, Zhou Y, Cheng C, Bhatia R, Lu R
Blood 2024 Nov 7;144(19):2018-2032
Blood 2024 Nov 7;144(19):2018-2032
PTPN20 promotes metastasis through activating NF-κB signaling in triple-negative breast cancer.
Zuo X, Zhao X, Zhang X, Li Q, Jiang X, Huang S, Chen X, Chen X, Jia W, Zou H, Shi D, Qian X
Breast cancer research : BCR 2024 Nov 6;26(1):155
Breast cancer research : BCR 2024 Nov 6;26(1):155
The inhibitory effect of Hypericum japonicum on H9N2 avian influenza virus.
Hu H, Li J, Zheng S, Zhao K, Xia Y, Wei X, Han M, Zhao Y, Peng O, Zhao Z, Chen Z, Su W, Cao Y, Wang Y, Xue C
Advanced biotechnology 2024 Nov 6;2(4):41
Advanced biotechnology 2024 Nov 6;2(4):41
NSUN2 Promotes Head and Neck Squamous Cell Carcinoma Progression by Targeting EMT-Related Gene LAMC2 in an m(5)C-YBX1-Dependent Manner.
Huang S, Cao C, Tang D, Liu Y, Zhou W, Liu L, Zheng X, He Q, Wang A
Biomedicines 2024 Nov 6;12(11)
Biomedicines 2024 Nov 6;12(11)
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
Li X, Sun H, Zhang L, Liang H, Zhang B, Yang J, Peng X, Sun J, Zhou Y, Zhai M, Jiang L, Zhu H, Duan W
European journal of pharmacology 2024 Nov 5;982:176894
European journal of pharmacology 2024 Nov 5;982:176894
Reactive astrocytes promote tumor progression by up-regulating tumor protocadherin 1 expression in lung cancer brain metastasis.
Tang M, Liang K, Duan W, Xia S, Shi D, Li E, Liu W, Wang Q
Biochemical and biophysical research communications 2024 Nov 5;732:150431
Biochemical and biophysical research communications 2024 Nov 5;732:150431
Perinatal exposure to PBEB aggravates liver injury via macrophage-derived TWEAK in male adult offspring mice under western diet.
Wang W, Shi X, Feng J, Le Y, Jin L, Lu D, Zhang Q, Wang C
Journal of hazardous materials 2024 Nov 5;479:135735
Journal of hazardous materials 2024 Nov 5;479:135735
Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury.
Lin H, Ma C, Zhuang X, Liu S, Liu D, Zhang M, Lu Y, Zhou G, Zhang C, Wang T, Zhang Z, Lv L, Zhang D, Ruan XZ, Xu Y, Chai R, Yu X, Sun JP, Chu B
Cell metabolism 2024 Nov 5;36(11):2402-2418.e10
Cell metabolism 2024 Nov 5;36(11):2402-2418.e10
Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy.
Mo H, Liu J, Su Z, Zhao DG, Ma YY, Zhang K, Wang Q, Fu C, Wang Y, Chen M, Hu B
European journal of medicinal chemistry 2024 Nov 5;277:116765
European journal of medicinal chemistry 2024 Nov 5;277:116765
Development of oxidative stress- and ferroptosis-related prognostic signature in gastric cancer and identification of CDH19 as a novel biomarker.
Wang S, Zhang S, Li X, Leng C, Li X, Lv J, Zhao S, Qiu W, Guo J
Human genomics 2024 Nov 5;18(1):121
Human genomics 2024 Nov 5;18(1):121
LncRNA DDX11-AS1 promotes breast cancer progression by targeting the miR-30c-5p/MTDH axis.
Li Y, Zhou M, Yang L, Liu S, Yang L, Xu B, Li X, Zhao H, Song Z
Scientific reports 2024 Nov 5;14(1):26745
Scientific reports 2024 Nov 5;14(1):26745
Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation.
Liu J, Xu L, Wang L, Wang Q, Yu L, Zhang S
Inflammatory bowel diseases 2024 Nov 4;30(11):1946-1956
Inflammatory bowel diseases 2024 Nov 4;30(11):1946-1956
Distinct roles of Kif6 and Kif9 in mammalian ciliary trafficking and motility.
Fang C, Pan X, Li D, Chen W, Huang Y, Chen Y, Li L, Gao Q, Liang X, Li D, Zhu X, Yan X
The Journal of cell biology 2024 Nov 4;223(11)
The Journal of cell biology 2024 Nov 4;223(11)
Establishment and validation of a prognostic model for idiopathic pulmonary fibrosis based on mitochondrial-related genes.
Wang X, Yang L, Wang Y, Dou X, Li Y, Wang K, Zhang H
Journal of thoracic disease 2024 Nov 30;16(11):7427-7445
Journal of thoracic disease 2024 Nov 30;16(11):7427-7445
GABPA inhibits tumorigenesis in clear cell renal cell carcinoma by regulating ferroptosis through ACSL4.
Wu Y, Wu Z, Yao M, Liu L, Song Y, Ma L, Liu C
Scientific reports 2024 Nov 3;14(1):26521
Scientific reports 2024 Nov 3;14(1):26521
SS31 alleviates LPS-induced acute lung injury by inhibiting inflammatory responses through the S100A8/NLRP3/GSDMD signaling pathway.
Luo P, Gu Q, Wang J, Li X, Li N, Yang W, Meng X, Zhao M
European journal of medical research 2024 Nov 29;29(1):567
European journal of medical research 2024 Nov 29;29(1):567
Proteomic analysis illustrates the potential involvement of dysregulated ribosome-related pathways and disrupted metabolism during retinoic acid-induced cleft palate development.
Zhang W, Chen L, Ma A, Jiang W, Xu M, Bai X, Zhou J, Tang S
BMC medical genomics 2024 Nov 29;17(1):280
BMC medical genomics 2024 Nov 29;17(1):280
A hypoxia-activated and microenvironment-remodeling nanoplatform for multifunctional imaging and potentiated immunotherapy of cancer.
Song J, Wang H, Meng X, Li W, Qi J
Nature communications 2024 Nov 29;15(1):10395
Nature communications 2024 Nov 29;15(1):10395
S100A7 orchestrates neutrophil chemotaxis and drives neutrophil extracellular traps (NETs) formation to facilitate lymph node metastasis in cervical cancer patients.
Ning Y, Chen Y, Tian T, Gao X, Liu X, Wang J, Chu H, Zhao C, Yang Y, Lei K, Ren H, Cui Z
Cancer letters 2024 Nov 28;605:217288
Cancer letters 2024 Nov 28;605:217288
Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healing.
Li Y, Dong L, Chen Y, Cai W, Yang G, Wang Y
Stem cell research & therapy 2024 Nov 28;15(1):455
Stem cell research & therapy 2024 Nov 28;15(1):455
Unveiling Smyd-2's Role in Cytoplasmic Nrf-2 Sequestration and Ferroptosis Induction in Hippocampal Neurons After Cerebral Ischemia/Reperfusion.
Liu D, Zhu Y
Cells 2024 Nov 28;13(23)
Cells 2024 Nov 28;13(23)
Matrine protects against experimental autoimmune encephalomyelitis through modulating microglial ferroptosis.
Feng F, Li X, Wang W, Dou M, Li S, Jin X, Chu Y, Zhu L
Biochemical and biophysical research communications 2024 Nov 26;735:150651
Biochemical and biophysical research communications 2024 Nov 26;735:150651
Defects in CYB5A and CYB5B impact sterol-C4 oxidation in cholesterol biosynthesis and demonstrate regulatory roles of dimethyl sterols.
Ma MY, Deng G, Zhu WZ, Sun M, Jiang LY, Li WH, Liu YB, Guo L, Song BL, Zhao X
Cell reports 2024 Nov 26;43(11):114912
Cell reports 2024 Nov 26;43(11):114912
Screening and validation of key genes associated with osteoarthritis.
He M, Yu Q, Xiao H, Dong H, Li D, Gu W
BMC musculoskeletal disorders 2024 Nov 25;25(1):954
BMC musculoskeletal disorders 2024 Nov 25;25(1):954
Therapeutic Potential of Oligo-Fucoidan in Mitigating Peritoneal Dialysis-Associated Fibrosis.
Chen YW, Wu MY, Huang NJ, Wu MS, Hsu YH, Liao CT, Chen CH
Marine drugs 2024 Nov 25;22(12)
Marine drugs 2024 Nov 25;22(12)
miR-122/NEGR1 axis contributes colorectal cancer liver metastasis by PI3K/AKT pathway and macrophage modulation.
Dai S, Zhuang H, Li Z, Chen Z, Chai Y, Zhou Q
Journal of translational medicine 2024 Nov 25;22(1):1060
Journal of translational medicine 2024 Nov 25;22(1):1060
Inhibition of lung tumorigenesis by transient reprogramming in cancer cells.
Pedrosa P, Zhang Z, Nuñez-Quintela V, Macias D, Ge J, Denholm M, Dyas A, Estevez-Souto V, Lado-Fernandez P, Gonzalez P, Gomez M, Martin JE, Da Silva-Alvarez S, Collado M, Muñoz-Espín D
Cell death & disease 2024 Nov 25;15(11):857
Cell death & disease 2024 Nov 25;15(11):857
C-terminal tagging enhances the detection sensitivity of interlekin receptor type 1.
Moriyama A, Imaoka S, Sasagawa T, Hosaka M, Kato I, Tamura H, Takeuchi R, Tsunoda M, Asano M
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Nov 24;70(10):43-48
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Nov 24;70(10):43-48
Perturbation of mammary epithelial cell apicobasal polarity by RHBDF1-facilitated nuclear translocation of PKCζ.
Zhao HY, Zhu YP, Wen Y, Sun J, Ding XY, Cao XY, Wu KL, Fu L, Li LY
Biological research 2024 Nov 24;57(1):90
Biological research 2024 Nov 24;57(1):90
TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo study.
Peng B, Feng Z, Yang A, Liu J, He J, Xu L, Tian C, Sheng X, Wang Y, Chen R, Wang X, Ren X, Geng B, Xia Y
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):226
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):226
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
Zhang M, Zhang Y, He J, Wang X, Wang Y, Li L, Tao L, Zhang M, Shen X
Chinese medicine 2024 Nov 22;19(1):164
Chinese medicine 2024 Nov 22;19(1):164
Capsaicin and Quercitrin Maintained Lipid Homeostasis of Hyperlipidemic Mice: Serum Metabolomics and Signaling Pathways.
Wu Y, Liu W, Wang R, Lian Y, Cheng X, Yang R, Wang X, Mi S
Foods (Basel, Switzerland) 2024 Nov 21;13(23)
Foods (Basel, Switzerland) 2024 Nov 21;13(23)
Non-Sugar Sweetener Rubusoside Alleviates Lipid Metabolism Disorder In Vivo and In Vitro by Targeting PPARγ/α, Lgals3, and Mknk2.
Huang W, Jiang M, Wang X, Pan D, Chen W, Fan L
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25601-25619
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25601-25619
Adipose stem cell exosomes, stimulated by pro-inflammatory factors, enhance immune evasion in triple-negative breast cancer by modulating the HDAC6/STAT3/PD-L1 pathway through the transporter UCHL1.
Zhu Q, Zhang K, Cao Y, Hu Y
Cancer cell international 2024 Nov 20;24(1):385
Cancer cell international 2024 Nov 20;24(1):385
Mechanism of cold exposure delaying wound healing in mice.
Li FX, Liu JJ, Lei LM, Li YH, Xu F, Lin X, Cui RR, Zheng MH, Guo B, Shan SK, Tang KX, Li CC, Wu YY, Duan JY, Cao YC, Wu YL, He SY, Chen X, Wu F, Yuan LQ
Journal of nanobiotechnology 2024 Nov 20;22(1):723
Journal of nanobiotechnology 2024 Nov 20;22(1):723
Co-targeting TMEM16A with a novel monoclonal antibody and EGFR with Cetuximab inhibits the growth and metastasis of esophageal squamous cell carcinoma.
Zheng Y, Meng L, Qu L, Zhao C, Wang L, Ma J, Liu C, Shou C
Journal of translational medicine 2024 Nov 20;22(1):1046
Journal of translational medicine 2024 Nov 20;22(1):1046
Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor.
Zhang X, Feng Y, Zhong Y, Ding R, Guo Y, Jiang F, Xing Y, Shi H, Bao H, Si Y
ACS chemical neuroscience 2024 Nov 20;15(22):4185-4201
ACS chemical neuroscience 2024 Nov 20;15(22):4185-4201
Inhibition of PA28γ expression can alleviate osteoarthritis by inhibiting endoplasmic reticulum stress and promoting STAT3 phosphorylation.
Mo H, Sun K, Hou Y, Ruan Z, He Z, Liu H, Li L, Wang Z, Guo F
Bone & joint research 2024 Nov 20;13(11):659-672
Bone & joint research 2024 Nov 20;13(11):659-672
Arginine methylation-dependent TRIM47 stability mediated by CARM1 promotes the metastasis of hepatocellular carcinoma.
Tang Y, Meng X, Luo X, Yao W, Tian L, Zhang Z, Zhao Y, Xiao J, Zhu H, Hu J
Cell death discovery 2024 Nov 20;10(1):477
Cell death discovery 2024 Nov 20;10(1):477
Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma.
Kang G, Song H, Bo L, Liu Q, Li Q, Li J, Pan P, Wang J, Jia Y, Sun H, Ma X
Cancer immunology, immunotherapy : CII 2024 Nov 2;74(1):11
Cancer immunology, immunotherapy : CII 2024 Nov 2;74(1):11
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Lao D, Gong Z, Li T, Mo X, Huang W
Neurochemical research 2024 Nov 19;50(1):21
Neurochemical research 2024 Nov 19;50(1):21
Identifying genetic targets in clinical subtypes of Parkinson's disease for optimizing pharmacological treatment strategies.
Kong D, Li C, Ma L, Du L, Jiang N, Zhao X, Zhang S, Zhao Z, Fang L, Du G
Signal transduction and targeted therapy 2024 Nov 18;9(1):320
Signal transduction and targeted therapy 2024 Nov 18;9(1):320
ATP6V1C1, associated with the tumor microenvironment and mTORC1 signaling pathway, is a potential diagnostic, prognostic, and therapeutic biomarker for hepatocellular carcinoma.
Pan Y, Chen H, Lv C, He W, Xu Y, Xuan Q
Discover oncology 2024 Nov 18;15(1):673
Discover oncology 2024 Nov 18;15(1):673
Esketamine improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation.
Li H, Hu W, Wu Z, Tian B, Ren Y, Zou X
European journal of pharmacology 2024 Nov 15;983:177014
European journal of pharmacology 2024 Nov 15;983:177014
Ankrd1 regulates endogenous cardiac regeneration in mice by modulating cyclin D1.
Liu L, Jiang Q, Du C, Yang T, Zhou L, Chen J, Gu L, Wang Q, Wang Z, Wang H, Wang L
European journal of pharmacology 2024 Nov 15;983:177005
European journal of pharmacology 2024 Nov 15;983:177005
Dapagliflozin suppressed gastric cancer growth via regulating OTUD5 mediated YAP1 deubiquitination.
Ren K, Wang X, Ma R, Chen H, Min T, Ma Y, Xie X, Wang W, Deng X, Zhou Z, Li K, Zhu K, Hao N, Dang C, Sun T, Zhang H
European journal of pharmacology 2024 Nov 15;983:177002
European journal of pharmacology 2024 Nov 15;983:177002
A novel mutation alters GNE bifunctional enzyme activity and leads to familial inherited GNE diseases.
Li Y, Li W, Fan B, Zhang Y, Li Z, Lin K, Huang K, Yang Z, Ma S, Sun H
Gene 2024 Nov 15;927:148750
Gene 2024 Nov 15;927:148750
CD248 interacts with ECM to promote hypertrophic scar formation and development.
Zhang L, Shang Y, Han C, Li M, Zhang J, Li Y, Shen K, Jia Y, Han D, Wen W, Yang Y, Hu D
Gene 2024 Nov 15;927:148730
Gene 2024 Nov 15;927:148730
Potential predictive value of immune-related genes FUCA1 and NCKAP1L for osteosarcoma metastasis.
Wang X, Dou J, Liu M, Zhang Y, Li Y, Tong Z
Gene 2024 Nov 15;927:148645
Gene 2024 Nov 15;927:148645
YAP1 Inhibition Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer.
Song H, Lu T, Han D, Zhang J, Gan L, Xu C, Liu S, Li P, Zhang K, Hu Z, Li H, Li Y, Zhao X, Zhang J, Xing N, Shi C, Wen W, Yang F, Qin W
Cancer research 2024 Nov 15;84(22):3728-3742
Cancer research 2024 Nov 15;84(22):3728-3742
Trimethylamine Induced Chronic Kidney Injury by Activating the ZBP1-NLRP3 Inflammasome Pathway.
Bai L, Chen Q, Li Y, Wu F, Jin M, Chen Y, Teng X, Jin S, Fan H, Wu Y
Physiological research 2024 Nov 15;73(5):779-789
Physiological research 2024 Nov 15;73(5):779-789
EHD1 promotes breast cancer metastasis through upregulating HIF2a expression via activating mTOR pathway.
Gao X, Li J, Feng X, Xie Y, Zhang J, Liu J, Wang B, Liu P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70168
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70168
Hippocampal cannabinoid type 2 receptor alleviates chronic neuropathic pain-induced cognitive impairment via microglial DUSP6 pathway in rats.
Xu L, Zhu A, Xu S, Zhao J, Song S, Zhu H, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70152
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70152
Supplemented Gegen Qinlian Decoction Formula attenuates podocyte mitochondrial fission and renal fibrosis in diabetic kidney disease by inhibiting TNF-α-mediated necroptosis, compared with empagliflozin.
Wang Y, Yu L, Li Y, Cha S, Shi L, Wang J, Ge F, Huang C, Huang H, Tu Y, Wan Y, Shen S
Journal of ethnopharmacology 2024 Nov 15;334:118572
Journal of ethnopharmacology 2024 Nov 15;334:118572
Proteomic and lipidomic analysis of the mechanism underlying astragaloside IV in mitigating ferroptosis through hypoxia-inducible factor 1α/heme oxygenase 1 pathway in renal tubular epithelial cells in diabetic kidney disease.
Liu J, Ren J, Zhou L, Tan K, Du D, Xu L, Cao W, Zhang Y
Journal of ethnopharmacology 2024 Nov 15;334:118517
Journal of ethnopharmacology 2024 Nov 15;334:118517
MANF inhibits NLRP3 inflammasome activation by competitively binding to DDX3X in paraquat-stimulated alveolar macrophages.
Pu Y, Han S, Chen J, Liu Z
Ecotoxicology and environmental safety 2024 Nov 15;287:117331
Ecotoxicology and environmental safety 2024 Nov 15;287:117331
Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation.
Li M, Zhu C, Yuan Y, Huang X, Wu L, Wu J, Yin H, Chai L, Qu W, Yan Y, Li P, Li X
iScience 2024 Nov 15;27(11):111145
iScience 2024 Nov 15;27(11):111145
Exploring heparin's protective mechanism against AGEs induced endothelial injury.
Shi J, Guan Y, Song H, Zhu L, Li J, Li Q, Hou N, Han F, Wang M, Zhang K, Shan M, Sun X, Qiu H
iScience 2024 Nov 15;27(11):111084
iScience 2024 Nov 15;27(11):111084
Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F-53B Exposure: The Role of PKA Cytoplasmic Retention.
Li SP, Zeng HX, Qin SJ, Li QQ, Wu LY, Wu QZ, Lin LZ, Dong GH, Zeng XW
Environment & health (Washington, D.C.) 2024 Nov 15;2(11):776-785
Environment & health (Washington, D.C.) 2024 Nov 15;2(11):776-785
Inhibiting NF-κB inducing kinase improved the motor performance of ALS animal model.
Cao M, Yi L, Xu Y, Tian Y, Li Z, Bi Y, Guo M, Li Y, Liu Y, Xu X, Sun J, Li C, Duan W
Brain research 2024 Nov 15;1843:149124
Brain research 2024 Nov 15;1843:149124
IL-32 aggravates metabolic disturbance in human nucleus pulposus cells by activating FAT4-mediated Hippo/YAP signaling.
Li P, Que Y, Wong C, Lin Y, Qiu J, Gao B, Zhou H, Hu W, Shi H, Peng Y, Huang D, Gao W, Qiu X, Liang A
International immunopharmacology 2024 Nov 15;141:112966
International immunopharmacology 2024 Nov 15;141:112966
Manganese-mediated potentiation of antitumor immune responses by enhancing KLRG1(+) Macrophage function.
Ge L, Guo H, Zhou W, Shi W, Yue J, Wu Y
International immunopharmacology 2024 Nov 15;141:112951
International immunopharmacology 2024 Nov 15;141:112951
Focusing on non-responders to infliximab with ulcerative colitis, what can we do first and next?
Pu D, Wang P, Wang X, Tian Y, Gong H, Ma X, Li M, Zhang D
International immunopharmacology 2024 Nov 15;141:112943
International immunopharmacology 2024 Nov 15;141:112943
Gal-1-mediated cytochrome p450 activation promotes fibroblast into myofibroblast differentiation in pulmonary fibrosis.
Weng J, Cheng Q, Yang J, Jin H, Zhang R, Guan J, Ma Y, Wang L, Chen C, Wang Z
International immunopharmacology 2024 Nov 15;141:112920
International immunopharmacology 2024 Nov 15;141:112920
Total glucosides of Picrorhizae Rhizome alleviate non-alcoholic steatohepatitis (NASH) by specifically targeting acyl-CoA oxidase 1.
Zhuo FF, Li XQ, Zhang J, Zhang FM, Song ZH, He Y, Ding L, Liu D, Tu PF, Ma XH, Zeng KW
Heliyon 2024 Nov 15;10(21):e39874
Heliyon 2024 Nov 15;10(21):e39874
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Wu Q, Chen M, Lin Y, Zhang J, Gao X, Wu Y, Wu C, Wen J, Li J, Li C, Bao W, Zhang D, Zheng M, Zhu A
Heliyon 2024 Nov 15;10(21):e38650
Heliyon 2024 Nov 15;10(21):e38650
Palladium-Mediated Bioorthogonal System for Prodrug Activation of N-Benzylbenzamide-Containing Tubulin Polymerization Inhibitors for the Treatment of Solid Tumors.
Li J, Zhang T, Wu D, He C, Weng H, Zheng T, Liu J, Yao H, Chen J, Ren Y, Zhu Z, Xu J, Xu S
Journal of medicinal chemistry 2024 Nov 14;67(21):19905-19924
Journal of medicinal chemistry 2024 Nov 14;67(21):19905-19924
Age-related STING suppression in macrophages contributes to increased viral load during influenza a virus infection.
Lauf T, Häder A, Hornung F, Reisser Y, Nietzsche S, Schanz F, Trümper V, Jeznach A, Brunke S, Doenst T, Skirecki T, Löffler B, Deinhardt-Emmer S
Immunity & ageing : I & A 2024 Nov 14;21(1):80
Immunity & ageing : I & A 2024 Nov 14;21(1):80
microRNA-637/661 ameliorate hypoxic-induced pulmonary arterial hypertension by targeting TRIM29 signaling pathway.
Jiang L, Tao W, Liu J, Yang A, Zhou J
Scientific reports 2024 Nov 14;14(1):27971
Scientific reports 2024 Nov 14;14(1):27971
Periodontitis promotes tumor growth and immune evasion via PD-1/PD-L1.
Wang S, Nie F, Yin Q, Tian H, Gong P, Ju J, Liu J, Yang P, Yang C
Cancer immunology, immunotherapy : CII 2024 Nov 13;74(1):22
Cancer immunology, immunotherapy : CII 2024 Nov 13;74(1):22
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Wang Y, Chen Y, Zhou T, Li J, Zhang N, Liu N, Zhou P, Mao Y
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal Domain.
Li P, Faraone JN, Hsu CC, Chamblee M, Liu Y, Zheng YM, Xu Y, Carlin C, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Bednash JS, Xu K, Liu SL
bioRxiv : the preprint server for biology 2024 Nov 13;
bioRxiv : the preprint server for biology 2024 Nov 13;
Nervonic acid improves depression like behaviors and demyelination of medial prefrontal cortex in chronic restraint stress mice.
Ma S, Lue Z, Xu G, Ma Y, Yuan W, Huang Z, Hu S, Yu L, Zhang X
Biochemical and biophysical research communications 2024 Nov 12;733:150696
Biochemical and biophysical research communications 2024 Nov 12;733:150696
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
Chatterjee S, Naeli P, Onar O, Simms N, Garzia A, Hackett A, Coyle K, Harris Snell P, McGirr T, Sawant TN, Dang K, Stoichkova ZV, Azam Y, Saunders MP, Braun M, Alain T, Tuschl T, McDade SS, Longley DB, Gkogkas CG, Adrain C, Knight JRP, Jafarnejad SM
Nucleic acids research 2024 Nov 11;52(20):12534-12548
Nucleic acids research 2024 Nov 11;52(20):12534-12548
PI3K p85α/HIF-1α accelerates the development of pulmonary arterial hypertension by regulating fatty acid uptake and mitophagy.
Chen C, Qin S, Song X, Wen J, Huang W, Sheng Z, Li X, Cao Y
Molecular medicine (Cambridge, Mass.) 2024 Nov 11;30(1):208
Molecular medicine (Cambridge, Mass.) 2024 Nov 11;30(1):208
More powerful dysregulation of Helicobacter pylori East Asian-type CagA on intracellular signalings.
Ji X, Sun Z, Wu H, Zhang J, Liu S, Cao X, Wang B, Wang F, Zhang Y, Li B, Feng J, Zhao H
BMC microbiology 2024 Nov 11;24(1):467
BMC microbiology 2024 Nov 11;24(1):467
ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis.
Cao L, Peng H, Chen Y, Xia B, Zeng T, Guo J, Yu F, Ye H, Zhang H, Chen X
Journal for immunotherapy of cancer 2024 Nov 11;12(11)
Journal for immunotherapy of cancer 2024 Nov 11;12(11)
SIRT1-Dependent Neuroprotection by Resveratrol in TOCP-Induced Spinal Cord Injury: Modulation of ER Stress and Autophagic Flux.
Tian X, Ou Y, Shi S, Zhou Q, Long S, Xiang Y, Zhao W, Long D
Toxics 2024 Nov 11;12(11)
Toxics 2024 Nov 11;12(11)
Role of Peptidyl Arginine Deiminase 4-Dependent Macrophage Extracellular Trap Formation in Type 1 Diabetes Pathogenesis.
Shen Y, Shi R, Lu S, Wang Y, Zhou Z, Wu C, You Q, Fan H, Wu J
Diabetes 2024 Nov 1;73(11):1862-1874
Diabetes 2024 Nov 1;73(11):1862-1874
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
Gao Q, Li N, Pan Y, Chu P, Zhou Y, Jia H, Cheng Y, Xue G, Song J, Zhang Y, Zhu H, Sun J, Zhang B, Sun Z, Fang D
Cancer letters 2024 Nov 1;604:217196
Cancer letters 2024 Nov 1;604:217196
The changes of tPA/PAI-1 system are associated with the ratio of BDNF/proBDNF in major depressive disorder and SSRIs antidepressant treatment.
Yang Z, Gao C, Li Z, Jiang T, Liang Y, Jiang T, Yu C, Yan S, Li P, Zhou L
Neuroscience 2024 Nov 1;559:220-228
Neuroscience 2024 Nov 1;559:220-228
Downregulation of heat shock protein 47 caused lysosomal dysfunction leading to excessive chondrocyte apoptosis.
Shi Y, He Y, Li Y, Zhang M, Liu Y, Wang H, Shen Z, Zhao X, Wang R, Ma T, Yang P, Chen J
Experimental cell research 2024 Nov 1;443(1):114294
Experimental cell research 2024 Nov 1;443(1):114294
Lanostane triterpenoids from Ganoderma calidophilum exhibit potent anti-tumor activity by inhibiting PTP1B.
Chen C, Xu R, Guo C, Li X, Zhao Y, Luo D
Chemico-biological interactions 2024 Nov 1;403:111253
Chemico-biological interactions 2024 Nov 1;403:111253
A heterozygous SPRY4 variant identified in female infertility characterized by reduced oocyte potential and early embryonic arrest.
Xia L, Huang J, Che Q, Zhang J, Zhang Z, Shen Y, Wang D, Zhong Y, Liu S, Du J
Human reproduction (Oxford, England) 2024 Nov 1;39(11):2618-2629
Human reproduction (Oxford, England) 2024 Nov 1;39(11):2618-2629
Establishment and characterization of a mouse model for studying kidney repair in diabetes.
Shu S, Wang H, Cai J, Chen A, Dong Z
American journal of physiology. Renal physiology 2024 Nov 1;327(5):F758-F774
American journal of physiology. Renal physiology 2024 Nov 1;327(5):F758-F774
Mode of action exploration for prostate epithelial cell injury caused by bisphenol A.
Liang B, Chen J, Wang L, Zhang L, Huang S, Zhou Y, Ni M, Zhang L, Lv X, Li X
Ecotoxicology and environmental safety 2024 Nov 1;286:117228
Ecotoxicology and environmental safety 2024 Nov 1;286:117228
SKI-606, a Src inhibitor, ameliorates benzene-induced hematotoxicity via blocking ROS/Src kinase-mediated p38 and Akt signaling pathways.
Chen C, Zhu Y, Li Q, Yu Z, Tan Y, Li F, Chen X, Jiang S, Yu K, Zhang S
Ecotoxicology and environmental safety 2024 Nov 1;286:117223
Ecotoxicology and environmental safety 2024 Nov 1;286:117223
Neuronostatin regulates neuronal function and energetic metabolism in Alzheimer's disease in a GPR107-dependent manner.
Yang S, Tang Q, Zhang Y, Du Y, Zhao X, Mei F, Li Y
Neuropharmacology 2024 Nov 1;258:110090
Neuropharmacology 2024 Nov 1;258:110090
Loss of interferon regulatory factor-1 prevents lung fibrosis by upregulation of pon1 expression.
Zhou A, Zhang X, Hu X, Li T, Peng W, Yang H, Deng D, Mo C, Lu R, Pan P
Respiratory research 2024 Nov 1;25(1):394
Respiratory research 2024 Nov 1;25(1):394
Ubiquitination of ATAD3A by TRIM25 exacerbates cerebral ischemia-reperfusion injury via regulating PINK1/Parkin signaling pathway-mediated mitophagy.
Li X, Guan L, Liu Z, Du Z, Yuan Q, Zhou F, Yang X, Lv M, Lv L
Free radical biology & medicine 2024 Nov 1;224:757-769
Free radical biology & medicine 2024 Nov 1;224:757-769
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
The Elabela-APJ axis attenuates sepsis-induced myocardial dysfunction by reducing pyroptosis by balancing the formation and degradation of autophagosomes.
Liu S, Liu FZ, Yan JY, Fang X, Xu ZP, Cai HL, Yang YJ, Yu YW
Free radical biology & medicine 2024 Nov 1;224:405-417
Free radical biology & medicine 2024 Nov 1;224:405-417
Ultrasound-mediated nanobubbles loaded with STAT6 siRNA inhibit TGF-β1-EMT axis in LUSC cells via overcoming the polarization of M2-TAMs.
Shu H, Ren ZJ, Li H, Zhang Y, Yin C, Nie F
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Nov 1;202:106894
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Nov 1;202:106894
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Zhao Y, Wang Y, Zheng H, Xu Q, Zhou K, Liu H, Xia Y, Wei DH, Jiang M, Tang ZH, Liu LS, Zheng H, Jiang Z
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Fingolimod, a sphingosine-1-phosphate receptor modulator, prevents neonatal bronchopulmonary dysplasia and subsequent airway remodeling in a murine model.
Sudhadevi T, Annadi A, Basa P, Jafri A, Natarajan V, Harijith A
Journal of applied physiology (Bethesda, Md. : 1985) 2024 Nov 1;137(5):1231-1242
Journal of applied physiology (Bethesda, Md. : 1985) 2024 Nov 1;137(5):1231-1242
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level.
Jiang Y, Xu S, Guo M, Lu Z, Wei X, An F, Xin X
Toxicology in vitro : an international journal published in association with BIBRA 2024 May;97:105809
Toxicology in vitro : an international journal published in association with BIBRA 2024 May;97:105809
Superoxide dismutase 2 scavenges ROS to promote osteogenic differentiation of human periodontal ligament stem cells by regulating Smad3 in alveolar bone-defective rats.
Qiu W, Sun Q, Li N, Chen Z, Wu H, Chen Z, Guo X, Fang F
Journal of periodontology 2024 May;95(5):469-482
Journal of periodontology 2024 May;95(5):469-482
Androgens exacerbate hepatic triglyceride accumulation in rats with polycystic ovary syndrome by downregulating MTTP expression.
Wang D, Zhao H, Xing C, Lv B, Wang X, He B
Endocrine 2024 May;84(2):735-744
Endocrine 2024 May;84(2):735-744
Study on the mechanism of arsenic-induced renal injury based on SWATH proteomics technology.
Chen X, Yan X, Tang X, Wang Y, Zhang X, Cao X, Ran X, Ma G, Hu T, Qureshi A, Luo P, Shen L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 May;83:127390
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 May;83:127390
Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway.
Zhang H, Hu S, Sanches JGP, Li Y, Wei Y, Pu C, Zhang J
Journal of physiology and biochemistry 2024 May;80(2):381-392
Journal of physiology and biochemistry 2024 May;80(2):381-392
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells.
Lin YH, Lin KL, Wang XW, Lee JJ, Wang FS, Wang PW, Lan MY, Liou CW, Lin TK
Mitochondrion 2024 May;76:101856
Mitochondrion 2024 May;76:101856
Interleukin-22 Alleviates Caerulein-Induced Acute Pancreatitis by Activating AKT/mTOR Pathway.
Fu X, Xiu Z, Xu Q, Yue R, Xu H
Digestive diseases and sciences 2024 May;69(5):1691-1700
Digestive diseases and sciences 2024 May;69(5):1691-1700
Activation of hepatic acetyl-CoA carboxylase by S-nitrosylation in response to diet.
Venetos NM, Stomberski CT, Qian Z, Premont RT, Stamler JS
Journal of lipid research 2024 May;65(5):100542
Journal of lipid research 2024 May;65(5):100542
Neuronal CFL1 upregulation in head and neck squamous cell carcinoma enhances tumor-nerve crosstalk and promotes tumor growth.
Liu R, Wang C, Sun Z, Shi X, Zhang Z, Luo J
Molecular carcinogenesis 2024 May;63(5):874-884
Molecular carcinogenesis 2024 May;63(5):874-884
p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
Liu J, Gao L, Zhou N, Jiang Z, Che S, Deng Y, Zang N, Ren L, Xie X, Xie J, Liu E
Virology 2024 May;593:110018
Virology 2024 May;593:110018
Identification of several African swine fever virus replication inhibitors by screening of a library of FDA-approved drugs.
Li T, Zheng J, Huang T, Wang X, Li J, Jin F, Wei W, Chen X, Liu C, Bao M, Zhao G, Huang L, Zhao D, Chen J, Bu Z, Weng C
Virology 2024 May;593:110014
Virology 2024 May;593:110014
Dihydroartemisinin, a potential PTGS1 inhibitor, potentiated cisplatin-induced cell death in non-small cell lung cancer through activating ROS-mediated multiple signaling pathways.
Ni L, Zhu X, Zhao Q, Shen Y, Tao L, Zhang J, Lin H, Zhuge W, Cho YC, Cui R, Zhu W
Neoplasia (New York, N.Y.) 2024 May;51:100991
Neoplasia (New York, N.Y.) 2024 May;51:100991
mTORC1 - TFEB pathway was involved in sodium arsenite induced lysosomal alteration, oxidative stress and genetic damage in BEAS-2B cells.
Ouyang D, Xiong Y, Hu Z, He J, He S, Liu R, Gao Z, Hu D
Toxicology 2024 May;504:153795
Toxicology 2024 May;504:153795
Salidroside Mediated the Nrf2/GPX4 Pathway to Attenuates Ferroptosis in Parkinson's Disease.
Shen J, Chen S, Li X, Wu L, Mao X, Jiang J, Zhu D
Neurochemical research 2024 May;49(5):1291-1305
Neurochemical research 2024 May;49(5):1291-1305
Inhibition of CK2 Diminishes Fibrotic Scar Formation and Improves Outcomes After Ischemic Stroke via Reducing BRD4 Phosphorylation.
Li X, Yang Q, Jiang P, Wen J, Chen Y, Huang J, Tian M, Ren J, Yang Q
Neurochemical research 2024 May;49(5):1254-1267
Neurochemical research 2024 May;49(5):1254-1267
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
Song X, Wang L, Cai P, Xu Y, Liu Q, Fan D
Toxicology and applied pharmacology 2024 May;486:116938
Toxicology and applied pharmacology 2024 May;486:116938
Dihydroartemisinin eliminates senescent cells by promoting autophagy-dependent ferroptosis via AMPK/mTOR signaling pathway.
Wan X, Li C, Tan YH, Zuo SQ, Deng FM, Sun J, Liu YL
Cell biology international 2024 May;48(5):726-736
Cell biology international 2024 May;48(5):726-736
Histological study of telocytes in mice intrauterine adhesion model and their positive effect on mesenchymal stem cells in vitro.
Wei X, Li H, Chen T, Yang X
Cell biology international 2024 May;48(5):647-664
Cell biology international 2024 May;48(5):647-664
Propane-2-sulfonic acid octadec-9-enyl-amide, a novel PPARα/γ dual agonist, attenuates molecular pathological alterations in learning memory in AD mice.
Li Y, Zhang Y, Wang Q, Wu C, Du G, Zeng Y, Song Z, Jiang X, Jiang X, Zhuo R, Li J
Neurological research 2024 May;46(5):416-425
Neurological research 2024 May;46(5):416-425
Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching.
Shen SC, Xu J, Cheng C, Xiang XJ, Hong BY, Zhang M, Gong C, Ma LK
Acta pharmacologica Sinica 2024 May;45(5):959-974
Acta pharmacologica Sinica 2024 May;45(5):959-974
Lidocaine inhibits migration of tenocytes by downregulating focal adhesion kinase and paxillin phosphorylation.
Chang HN, Chen CK, Yu TY, Pang JS, Hsu CC, Lin LP, Tsai WC
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 May;42(5):985-992
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 May;42(5):985-992
Enhancing therapeutic efficacy in breast cancer: a study on the combined cytotoxic effects of doxorubicin and MPC-3100.
Gökşen Tosun N
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3249-3259
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3249-3259
LncRNA PFAR facilitates the proliferation and migration of papillary thyroid carcinoma by competitively binding to miR-15a.
Fang T, Yu K
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3037-3048
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3037-3048
Co-encapsulation of granzyme B and perforin in nanocapsules for tumour therapy: biomimicking immune cells.
Shi Z, Yan J, Zhao M, Li S, She T, Qian X
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:658-667
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:658-667
Effect of GLIS1 on the Lymph Node Metastasis of Cervical Squamous Carcinoma Based on Transcriptome Analysis.
Huang J, Zhao Y
Reproductive sciences (Thousand Oaks, Calif.) 2024 May;31(5):1332-1344
Reproductive sciences (Thousand Oaks, Calif.) 2024 May;31(5):1332-1344
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
Liu K, Wei ZY, Zhong XH, Liu X, Chen H, Pan Y, Zeng W
Tissue engineering. Part A 2024 May;30(9-10):381-392
Tissue engineering. Part A 2024 May;30(9-10):381-392
Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress.
Ji XD, Yang D, Cui XY, Lou LX, Nie B, Zhao JL, Zhao MJ, Wu AM
Chinese journal of integrative medicine 2024 May;30(5):398-407
Chinese journal of integrative medicine 2024 May;30(5):398-407
Radiotherapy upregulated immune checkpoints contribute to the development of second primary OSCC.
Wang L, Wang S, Zhang J, Peng J, Cheng B, Li H, Hu Q
Oral diseases 2024 May;30(4):2188-2201
Oral diseases 2024 May;30(4):2188-2201
Hypoxia inducible factor-1α facilitates transmissible gastroenteritis virus replication by inhibiting type I and type III interferon production.
Zhang Y, Rui X, Li Y, Zhang Y, Cai Y, Tan C, Yang N, Liu Y, Fu Y, Liu G
Veterinary microbiology 2024 May;292:110055
Veterinary microbiology 2024 May;292:110055
Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
Liu J, Wei AH, Liu TT, Ji XH, Zhang Y, Yan F, Chen MX, Hu JB, Zhou SY, Shi JS, Jin H, Jin F
The FEBS journal 2024 May;291(10):2221-2241
The FEBS journal 2024 May;291(10):2221-2241
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Lan Y, Tian F, Tang H, Pu P, He Q, Duan L
Molecular medicine reports 2024 May;29(5)
Molecular medicine reports 2024 May;29(5)
Expression of human dCTP pyrophosphatase 1 (DCTPP1) and its association with cisplatin resistance characteristics in ovarian cancer.
Wang Y, Chen X, Chen Q, Liu T, Wu Y, Huang L, Chen Y
Journal of cellular and molecular medicine 2024 May;28(9):e18371
Journal of cellular and molecular medicine 2024 May;28(9):e18371
Improved therapeutic effects on vascular intimal hyperplasia by mesenchymal stem cells expressing MIR155HG that function as a ceRNA for microRNA-205.
Bai X, Qi Z, Cai C, Song H, Song G, Zhao X
Journal of cellular and molecular medicine 2024 May;28(9):e18351
Journal of cellular and molecular medicine 2024 May;28(9):e18351
Relationship between circadian rhythm-related genes and extracellular matrix: implications for sleep deprivation.
Liu X, Sun J, Ling Z, Dong T
Sleep & breathing = Schlaf & Atmung 2024 May;28(2):697-705
Sleep & breathing = Schlaf & Atmung 2024 May;28(2):697-705
Effects of total saikosaponins on CYP3A4 and CYP1A2 in HepaRG cells.
Tang Y, Li H, Tang J, Hu L, Ma F, Liu Y, Tang F
Experimental and therapeutic medicine 2024 May;27(5):217
Experimental and therapeutic medicine 2024 May;27(5):217
Prognostic biomarker HIF1α and its correlation with immune infiltration in gliomas.
Ding Z, Zhang J, Li L, Wang C, Mei J
Oncology letters 2024 May;27(5):193
Oncology letters 2024 May;27(5):193
Nattokinase attenuates endothelial inflammation through the activation of SRF and THBS1.
Chiu HW, Chou CL, Lee KT, Shih CC, Huang TH, Sung LC
International journal of biological macromolecules 2024 May;268(Pt 2):131779
International journal of biological macromolecules 2024 May;268(Pt 2):131779
Cardiac-specific overexpression of CREM-IbΔC-X via CRISPR/Cas9 in mice presents a new model of atrial cardiomyopathy with spontaneous atrial fibrillation.
Chen J, Qin H, Hao J, Wang Q, Chen S, Yang G, Li M, Zhu X, Wang D, Chen H, Cui C, Chen M
Translational research : the journal of laboratory and clinical medicine 2024 May;267:54-66
Translational research : the journal of laboratory and clinical medicine 2024 May;267:54-66
NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway.
Ren S, Chen Y, Wang Q, Song L, Xin Z, Shi M, Liu X
Pathology, research and practice 2024 May;257:155323
Pathology, research and practice 2024 May;257:155323
METTL14 affects UVB-induced human dermal fibroblasts photoaging via miR-100-3p biogenesis in an m(6)A-dependent manner.
Chen L, Hu Y, Zhang M, Liu L, Ma J, Xu Z, Zhang J, Gu H, Chen K
Aging cell 2024 May;23(5):e14123
Aging cell 2024 May;23(5):e14123
Genetic and pharmacological modulation of lamin A farnesylation determines its function and turnover.
Foo MXR, Ong PF, Yap ZX, Maric M, Bong CJS, Dröge P, Burke B, Dreesen O
Aging cell 2024 May;23(5):e14105
Aging cell 2024 May;23(5):e14105
DDX20 positively regulates the interferon pathway to inhibit viral infection.
Chen Z, Zhang J, Feng T, Wang X, Zhou S, Pan W, Chen Z, Yan Y, Dai J
Antiviral research 2024 May;225:105875
Antiviral research 2024 May;225:105875
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Yin HT, Hui-Lu, Yang JH, Li Q, Li M, Zhao QQ, Wen ZP
Biochemical pharmacology 2024 May;223:116113
Biochemical pharmacology 2024 May;223:116113
Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy.
Xu Y, Qian C, Wang Q, Song L, He Z, Liu W, Wan W
Autophagy 2024 May;20(5):1134-1146
Autophagy 2024 May;20(5):1134-1146
Near-Infrared Light-Driven Nanoparticles for Cancer Photoimmunotherapy by Synergizing Immune Cell Death and Epigenetic Regulation.
Wang H, Xiong X, Zhang J, Wu M, Gu Y, Chen Y, Gu Y, Wang P
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(21):e2309202
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(21):e2309202
Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells.
Zhang Y, Tian K, Wei W, Mi W, Lu F, Liu Z, Zhu Q, Zhang X, Geng P, Qiu J, Song Y, Zha D
Neural regeneration research 2024 May;19(5):1119-1125
Neural regeneration research 2024 May;19(5):1119-1125
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
Caffeic acid alleviates skeletal muscle atrophy in 5/6 nephrectomy rats through the TLR4/MYD88/NF-kB pathway.
He J, He Z, Wang H, Zhang C, Pei T, Yan S, Yan Y, Wang F, Chen Y, Yuan N, Wang M, Xiao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116556
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116556
Trimethylamine-N-oxide aggravated the sympathetic excitation in D-galactose induced aging rats by down-regulating P2Y12 receptor in microglia.
Wang P, Mi Y, Yu H, Teng X, Jin S, Xiao L, Xue H, Tian D, Guo Q, Wu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116549
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116549
Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.
Shen X, Xia Y, Lu H, Zheng P, Wang J, Chen Y, Xu C, Qiu C, Zhang Y, Xiao Z, Zou P, Cui R, Ni D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116507
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116507
Pilose antler extract promotes hair growth in androgenic alopecia mice by promoting the initial anagen phase.
Liu M, He G, Wang F, Sun Y, Ma S, Hao Y, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116503
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116503
Identification of CREB5 as a prognostic and immunotherapeutic biomarker in glioma through multi-omics pan-cancer analysis.
Wu Z, Wang X, Wu H, Du S, Wang Z, Xie S, Zhang R, Chen G, Chen H
Computers in biology and medicine 2024 May;173:108307
Computers in biology and medicine 2024 May;173:108307
The circadian clock gene, BMAL1, promotes radiosensitization in nasopharyngeal carcinoma by inhibiting the epithelial-to-mesenchymal transition via the TGF-β1/Smads/Snail1 axis.
Li Y, Zhou Y, Zhao C, Liu L, He Q, Shang K, Xu X, Luo X, Zhou D, Jin F
Oral oncology 2024 May;152:106798
Oral oncology 2024 May;152:106798
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Wang J, Wang X, Chen F, Ning Q, Liu Y, Zhu Y, Wei W, Leng M, Wang Z, Jin P, Li Q
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
Epidermal Stem Cell Derived Exosomes Alleviate Excessive Autophagy Induced Endothelial Cell Apoptosis by Delivering miR200b-3p to Diabetic Wounds.
Xu H, Yang H, Wang Z, Tang Q, Cao X, Chen C, Dong Y, Xu Z, Lv D, Rong Y, Chen M, Tang B, Deng W, Zhu J, Hu Z
The Journal of investigative dermatology 2024 May;144(5):1134-1147.e2
The Journal of investigative dermatology 2024 May;144(5):1134-1147.e2
SPP1 represents a therapeutic target that promotes the progression of oesophageal squamous cell carcinoma by driving M2 macrophage infiltration.
Wang C, Li Y, Wang L, Han Y, Gao X, Li T, Liu M, Dai L, Du R
British journal of cancer 2024 May;130(11):1770-1782
British journal of cancer 2024 May;130(11):1770-1782
Paris polyphylla ethanol extract and polyphyllin I ameliorate adenomyosis by inhibiting epithelial-mesenchymal transition.
Shi YX, Xu L, Wang X, Zhang KK, Zhang CY, Liu HY, Ding PP, Shi W, Liu ZY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155461
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155461
TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway.
Shu B, Zhou Y, Lei G, Peng Y, Ding C, Li Z, He C
Cancer science 2024 May;115(5):1476-1491
Cancer science 2024 May;115(5):1476-1491
Cerebral furin deficiency causes hydrocephalus in mice.
Xie S, Xie X, Tang J, Luo B, Chen J, Wen Q, Zhou J, Chen G
Genes & diseases 2024 May;11(3):101009
Genes & diseases 2024 May;11(3):101009
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
He Z, Song C, Li S, Dong C, Liao W, Xiong Y, Yang S, Liu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
Deciphering the Therapeutic Role of Lactate in Combating Disuse-Induced Muscle Atrophy: An NMR-Based Metabolomic Study in Mice.
Zhou Y, Liu X, Qi Z, Yang L, Huang C, Lin D
Molecules (Basel, Switzerland) 2024 May 9;29(10)
Molecules (Basel, Switzerland) 2024 May 9;29(10)
RRP8, associated with immune infiltration, is a prospective therapeutic target in hepatocellular carcinoma.
You K, Du X, Zhao Y, Wen F, Lu Z, Fan H
Journal of cancer research and clinical oncology 2024 May 9;150(5):245
Journal of cancer research and clinical oncology 2024 May 9;150(5):245
Expression and Purification of Recombinant Bowman-Birk Trypsin Inhibitor from Foxtail Millet Bran and Its Anticolorectal Cancer Effect In Vitro and In Vivo.
Zhang H, Qiao Q, Zhao Y, Zhang L, Shi J, Wang N, Li Z, Shan S
Journal of agricultural and food chemistry 2024 May 8;72(18):10439-10450
Journal of agricultural and food chemistry 2024 May 8;72(18):10439-10450
Association between NDUFS1 from urinary extracellular vesicles and decreased differential renal function in children with ureteropelvic junction obstruction.
Bu L, Zhang L, Wang X, Du G, Wu R, Liu W
BMC nephrology 2024 May 8;25(1):158
BMC nephrology 2024 May 8;25(1):158
Brucella Manipulates Host Cell Ferroptosis to Facilitate Its Intracellular Replication and Egress in RAW264.7 Macrophages.
Zhang G, Hu H, Yin Y, Tian M, Bu Z, Ding C, Yu S
Antioxidants (Basel, Switzerland) 2024 May 8;13(5)
Antioxidants (Basel, Switzerland) 2024 May 8;13(5)
Gingipain-carrying outer membrane vesicles from Porphyromonas gingivalis cause barrier dysfunction of Caco-2 cells by releasing gingipain into the cytosol.
Nonaka S, Okamoto R, Katsuta Y, Kanetsuki S, Nakanishi H
Biochemical and biophysical research communications 2024 May 7;707:149783
Biochemical and biophysical research communications 2024 May 7;707:149783
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q
Cell metabolism 2024 May 7;36(5):1059-1075.e9
Cell metabolism 2024 May 7;36(5):1059-1075.e9
FTH1 overexpression using a dCasRx translation enhancement system protects the kidney from calcium oxalate crystal-induced injury.
He Z, Dong C, Song T, Zhou J, Xu T, He R, Li S
Cellular & molecular biology letters 2024 May 7;29(1):65
Cellular & molecular biology letters 2024 May 7;29(1):65
GJB3: a comprehensive biomarker in pan-cancer prognosis and immunotherapy prediction.
Zeng J, Li X, Zhang Y, Zhang B, Wang H, Bao S, Zu L, Zhang H, Cheng Y, Tang Q, Xu X, Xu S, Song Z
Aging 2024 May 7;16(9):7647-7667
Aging 2024 May 7;16(9):7647-7667
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Brenner D, Sieverding K, Srinidhi J, Zellner S, Secker C, Yilmaz R, Dyckow J, Amr S, Ponomarenko A, Tunaboylu E, Douahem Y, Schlag JS, Rodríguez Martínez L, Kislinger G, Niemann C, Nalbach K, Ruf WP, Uhl J, Hollenbeck J, Schirmer L, Catanese A, Lobsiger CS, Danzer KM, Yilmazer-Hanke D, Münch C, Koch P, Freischmidt A, Fetting M, Behrends C, Parlato R, Weishaupt JH
The Journal of experimental medicine 2024 May 6;221(5)
The Journal of experimental medicine 2024 May 6;221(5)
Protective Effects of an Oligo-Fucoidan-Based Formula against Osteoarthritis Development via iNOS and COX-2 Suppression following Monosodium Iodoacetate Injection.
Chiang YF, Huang KC, Wang KL, Huang YJ, Chen HY, Ali M, Shieh TM, Hsia SM
Marine drugs 2024 May 6;22(5)
Marine drugs 2024 May 6;22(5)
Irradiated microparticles suppress prostate cancer by tumor microenvironment reprogramming and ferroptosis.
Deng Z, Li B, Yang M, Lu L, Shi X, Lovell JF, Zeng X, Hu W, Jin H
Journal of nanobiotechnology 2024 May 5;22(1):225
Journal of nanobiotechnology 2024 May 5;22(1):225
Systemic LPS Administration Stimulates the Activation of Non-Neuronal Cells in an Experimental Model of Spinal Muscular Atrophy.
Karafoulidou E, Kesidou E, Theotokis P, Konstantinou C, Nella MK, Michailidou I, Touloumi O, Polyzoidou E, Salamotas I, Einstein O, Chatzisotiriou A, Boziki MK, Grigoriadis N
Cells 2024 May 4;13(9)
Cells 2024 May 4;13(9)
Decidual natural killer cells dysfunction is caused by IDO downregulation in dMDSCs with Toxoplasma gondii infection.
Wang Y, Zhao X, Li Z, Wang W, Jiang Y, Zhang H, Liu X, Ren Y, Xu X, Hu X
Communications biology 2024 May 31;7(1):669
Communications biology 2024 May 31;7(1):669
Dihydroartemisinin alleviates doxorubicin-induced cardiotoxicity and ferroptosis by activating Nrf2 and regulating autophagy.
Lin ZH, Xiang HQ, Yu YW, Xue YJ, Wu C, Lin C, Ji KT
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23677
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23677
Mitochondria transplantation alleviates cardiomyocytes apoptosis through inhibiting AMPKα-mTOR mediated excessive autophagy.
Jin N, Zhang M, Zhou L, Jin S, Cheng H, Li X, Shi Y, Xiang T, Zhang Z, Liu Z, Zhao H, Xie J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23655
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23655
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Wu W, Jia H, Chen S, Ma X, Zhou S, Qiu L, Wu X, Li P, Chu H, Zhang G
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability.
Wang C, Wang X, Zhang Y, Mi Y, Han Y, Zhi Y, Zhao R, Cui N, Ma Q, Zhang H, Xue D, Qiao R, Han J, Yu Y, Li J, Shaiea M, Liu D, Gu G, Wang C
Acta biochimica et biophysica Sinica 2024 May 30;56(12):1802-1812
Acta biochimica et biophysica Sinica 2024 May 30;56(12):1802-1812
Exosome-derived circUPF2 enhances resistance to targeted therapy by redeploying ferroptosis sensitivity in hepatocellular carcinoma.
Dong FL, Xu ZZ, Wang YQ, Li T, Wang X, Li J
Journal of nanobiotechnology 2024 May 30;22(1):298
Journal of nanobiotechnology 2024 May 30;22(1):298
PD-1/PD-L1 axis is involved in the interaction between microglial polarization and glioma.
Wang XP, Guo W, Chen YF, Hong C, Ji J, Zhang XY, Dong YF, Sun XL
International immunopharmacology 2024 May 30;133:112074
International immunopharmacology 2024 May 30;133:112074
CD47, a novel YAP target gene, contributes to hepatic stellate cell activation and liver fibrosis induced by high-fat diet.
Li Y, Dong L, Yin X, Wang X, Zhu X, Zheng P, Tang Y
Heliyon 2024 May 30;10(10):e31621
Heliyon 2024 May 30;10(10):e31621
Patient tissue-derived FGFR4-variant and wild-type colorectal cancer organoid development and anticancer drug sensitivity testing.
Lin H, Fu H, Sun S, Yin H, Yuan J, Liao J
Heliyon 2024 May 30;10(10):e30985
Heliyon 2024 May 30;10(10):e30985
CCR2 antagonist attenuates calcium oxalate-induced kidney oxidative stress and inflammation by regulating macrophage activation.
Wang X, Xie L, Liu C
Experimental animals 2024 May 3;73(2):211-222
Experimental animals 2024 May 3;73(2):211-222
Transmembrane protein modulates seizure in epilepsy: evidence from temporal lobe epilepsy patients and mouse models.
Zhang H, Zhou Z, Qin J, Yang J, Huang H, Yang X, Luo Z, Zheng Y, Peng Y, Chen Y, Xu Z
Experimental animals 2024 May 3;73(2):162-174
Experimental animals 2024 May 3;73(2):162-174
Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy.
Li YP, Huang ZJ, He QK, Li YX, Zhao XP, Ma ZQ, Qin MJ, Chen AW, Wei Q, Wang Y, Lu CH
Journal of proteome research 2024 May 3;23(5):1713-1724
Journal of proteome research 2024 May 3;23(5):1713-1724
VDR is a potential prognostic biomarker and positively correlated with immune infiltration: a comprehensive pan-cancer analysis with experimental verification.
Xia X, Xu F, Dai D, Xiong A, Sun R, Ling Y, Qiu L, Wang R, Ding Y, Lin M, Li H, Xie Z
Bioscience reports 2024 May 29;44(5)
Bioscience reports 2024 May 29;44(5)
αO-Conotoxin GeXIVA[1,2] Suppresses In Vivo Tumor Growth of Triple-Negative Breast Cancer by Inhibiting AKT-mTOR, STAT3 and NF-κB Signaling Mediated Proliferation and Inducing Apoptosis.
Guo X, He L, Xu W, Wang W, Feng X, Fu Y, Zhang X, Ding RB, Qi X, Bao J, Luo S
Marine drugs 2024 May 29;22(6)
Marine drugs 2024 May 29;22(6)
Machine learning-based identification and immune characterization of ferroptosis-related molecular clusters in osteoarthritis and validation.
Guo X, Feng X, Yang Y, An W, Bai L
Aging 2024 May 29;16(11):9437-9459
Aging 2024 May 29;16(11):9437-9459
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.
Tang Y, Wu J, Sun X, Tan S, Li W, Yin S, Liu L, Chen Y, Liu Y, Tan Q, Jiang Y, Yang W, Huang W, Weng C, Wu Q, Lu Y, Yuan H, Xiao Q, Chen AF, Xu Q, Billiar TR, Cai J
Cell reports 2024 May 28;43(5):114237
Cell reports 2024 May 28;43(5):114237
USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation.
Zhao B, Xia Z, Yang B, Guo Y, Zhou R, Gu M, Liu M, Li Q, Bai W, Huang J, Zhang X, Zhu C, Leung KT, Chen C, Dong J
Cell reports 2024 May 28;43(5):114194
Cell reports 2024 May 28;43(5):114194
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Induce Fetal Wound Healing Features Revealed by Single-Cell RNA Sequencing.
Liu Y, Zhang M, Wang C, Chen H, Su D, Yang C, Tao Y, Lv X, Zhou Z, Li J, Liao Y, You J, Wang Z, Cheng F, Yang R
ACS nano 2024 May 28;18(21):13696-13713
ACS nano 2024 May 28;18(21):13696-13713
Micropeptide AF127577.4-ORF hidden in a lncRNA diminishes glioblastoma cell proliferation via the modulation of ERK2/METTL3 interaction.
Du B, Zhang Z, Jia L, Zhang H, Zhang S, Wang H, Cheng Z
Scientific reports 2024 May 27;14(1):12090
Scientific reports 2024 May 27;14(1):12090
Effect of M0 macrophage-derived exosome miR-181d-5p targeting BCL-2 to regulate NLRP3/caspase-1/GSDMD pathway on human renal mesangial cells pyroptosis.
Chai F, Chang X, Lin Y, Pang X, Luo S, Huang H, Qin L, Lan Y, Zeng Y, Wang C
Gene 2024 May 25;908:148289
Gene 2024 May 25;908:148289
BDTX-189, a novel tyrosine kinase inhibitor, inhibits cell activity via ERK and AKT pathways in the EGFR C797S triple mutant cells.
Wang R, Cui W, Li L, Wei X, Chu C, Zhang G, Liu C, Xu H, Liu C, Wang K, Li Y, An L
Chemico-biological interactions 2024 May 25;395:111033
Chemico-biological interactions 2024 May 25;395:111033
α5-nAChR/ADAM10 signaling mediates nicotine-related cutaneous melanoma progression via STAT3 activation.
Li X, Meng X, Fan H, Wang Y, Jia Y, Jiao J, Ma X
Archives of dermatological research 2024 May 25;316(6):269
Archives of dermatological research 2024 May 25;316(6):269
WTAP-mediated m(6)A modification of lncRNA Snhg1 improves myocardial ischemia-reperfusion injury via miR-361-5p/OPA1-dependent mitochondrial fusion.
Liu L, Wu J, Lu C, Ma Y, Wang J, Xu J, Yang X, Zhang X, Wang H, Xu J, Zhang J
Journal of translational medicine 2024 May 25;22(1):499
Journal of translational medicine 2024 May 25;22(1):499
A new prognostic model based on gamma-delta T cells for predicting the risk and aiding in the treatment of clear cell renal cell carcinoma.
Wu Y, Yao M, Wu Z, Ma L, Liu C
Discover oncology 2024 May 25;15(1):185
Discover oncology 2024 May 25;15(1):185
Matrix stiffening promotes chondrocyte senescence and the osteoarthritis development through downregulating HDAC3.
Fu B, Shen J, Zou X, Sun N, Zhang Z, Liu Z, Zeng C, Liu H, Huang W
Bone research 2024 May 24;12(1):32
Bone research 2024 May 24;12(1):32
Ursonic acid from medicinal herbs inhibits PRRSV replication through activation of the innate immune response by targeting the phosphatase PTPN1.
Yang Y, Gao Y, Sun H, Bai J, Zhang J, Zhang L, Liu X, Sun Y, Jiang P
Veterinary research 2024 May 23;55(1):67
Veterinary research 2024 May 23;55(1):67
Xiaoyaosan promotes neurotransmitter transmission and alleviates CUMS-induced depression by regulating the expression of Oct1 and Oct3 in astrocytes of the prefrontal cortex.
Wu Y, Liu L, Zhao Y, Li X, Hu J, Li H, Zhao R
Journal of ethnopharmacology 2024 May 23;326:117923
Journal of ethnopharmacology 2024 May 23;326:117923
Anti-papillary thyroid carcinoma effects of dioscorea bulbifera L. through ferroptosis and the PI3K/AKT pathway based on network pharmacology and experimental validation.
Gao Y, Yang Z, Ji T, Zhou P, Geng L, Gao X
Journal of ethnopharmacology 2024 May 23;326:117912
Journal of ethnopharmacology 2024 May 23;326:117912
An integrated network pharmacology, molecular docking and experiment validation study to investigate the potential mechanism of Isobavachalcone in the treatment of osteoarthritis.
Fan Y, Yin L, Zhong X, He Z, Meng X, Chai F, Kong M, Zhang Q, Xia C, Tong Y, Bi Q
Journal of ethnopharmacology 2024 May 23;326:117827
Journal of ethnopharmacology 2024 May 23;326:117827
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
He J, Yi J, Ji L, Dai L, Chen Y, Xue W
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
Respiratory Syncytial Virus Vaccine Design Using Structure-Based Machine-Learning Models.
McCarty TC, Vaisman II
Viruses 2024 May 22;16(6)
Viruses 2024 May 22;16(6)
Oral Administration of Deer Bone Collagen Peptide Can Enhance the Skin Hydration Ability and Antioxidant Ability of Aging Mice Induced by D-Gal, and Regulate the Synthesis and Degradation of Collagen.
Zhang K, Zhao C, Liu K, Feng R, Zhao Y, Zong Y, Du R
Nutrients 2024 May 21;16(11)
Nutrients 2024 May 21;16(11)
Enhanced Efficacy against Drug-Resistant Tumors Enabled by Redox-Responsive Mesoporous-Silica-Nanoparticle-Supported Lipid Bilayers as Targeted Delivery Vehicles.
Yang S, Zhang B, Zhao X, Zhang M, Zhang M, Cui L, Zhang L
International journal of molecular sciences 2024 May 20;25(10)
International journal of molecular sciences 2024 May 20;25(10)
The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging.
Xu M, Wei X, Wang J, Li Y, Huang Y, Cheng A, He F, Zhang L, Zhang C, Liu Y
Aging and disease 2024 May 20;16(2):1120-1140
Aging and disease 2024 May 20;16(2):1120-1140
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Wang H, Wang B, Wu M, Lu J, Duan P
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
AKAP8 promotes ovarian cancer progression and antagonizes PARP inhibitor sensitivity through regulating hnRNPUL1 transcription.
Mobet Y, Wang H, Wei Q, Liu X, Yang D, Zhao H, Yang Y, Ngono Ngane RA, Souopgui J, Xu J, Liu T, Yi P
iScience 2024 May 17;27(5):109744
iScience 2024 May 17;27(5):109744
Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging.
Haga M, Iida K, Okada M
iScience 2024 May 17;27(5):109708
iScience 2024 May 17;27(5):109708
Increased Thyroid DPP4 Expression Is Associated With Inflammatory Process in Patients With Hashimoto Thyroiditis.
Wen X, Chang X, He X, Cai Q, Wang G, Liu J
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1517-1525
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1517-1525
Sequential glycosylations at the multibasic cleavage site of SARS-CoV-2 spike protein regulate viral activity.
Wang S, Ran W, Sun L, Fan Q, Zhao Y, Wang B, Yang J, He Y, Wu Y, Wang Y, Chen L, Chuchuay A, You Y, Zhu X, Wang X, Chen Y, Wang Y, Chen YQ, Yuan Y, Zhao J, Mao Y
Nature communications 2024 May 16;15(1):4162
Nature communications 2024 May 16;15(1):4162
Functional metabolomics reveals arsenic-induced inhibition of linoleic acid metabolism in mice kidney in drinking water.
He T, Xiong L, Lin K, Yi J, Duan C, Zhang J
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123949
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123949
Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects.
Zhang Z, Ge M, Wu D, Li W, Chen W, Liu P, Zhang H, Yang Y
Carbohydrate polymers 2024 May 15;332:121916
Carbohydrate polymers 2024 May 15;332:121916
Sialyltransferase ST3GAL6 silencing reduces α2,3-sialylated glycans to regulate autophagy by decreasing HSPB8-BAG3 in the brain with hepatic encephalopathy.
Li X, Xiao Y, Li P, Zhu Y, Guo Y, Bian H, Li Z
Journal of Zhejiang University. Science. B 2024 May 15;25(6):485-498
Journal of Zhejiang University. Science. B 2024 May 15;25(6):485-498
TRIM25 predominately associates with anti-viral stress granules.
Shang Z, Zhang S, Wang J, Zhou L, Zhang X, Billadeau DD, Yang P, Zhang L, Zhou F, Bai P, Jia D
Nature communications 2024 May 15;15(1):4127
Nature communications 2024 May 15;15(1):4127
Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes.
Mezincescu AM, Rudd A, Cheyne L, Horgan G, Philip S, Cameron D, van Loon L, Whitfield P, Gribbin R, Hu MK, Delibegovic M, Fielding B, Lobley G, Thies F, Newby DE, Gray S, Henning A, Dawson D
Nature communications 2024 May 15;15(1):3690
Nature communications 2024 May 15;15(1):3690
Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3'UTR to decrease the expression of CD82.
You G, Li Z, Li L, Xu C
Heliyon 2024 May 15;10(9):e30702
Heliyon 2024 May 15;10(9):e30702
Sialic acids as attachment factors in mosquitoes mediating Japanese encephalitis virus infection.
He Y, Miao C, Yang S, Xu C, Liu Y, Zhu X, Wen Y, Wu R, Zhao Q, Huang X, Yan Q, Lang Y, Zhao S, Wang Y, Han X, Cao S, Hu Y, Du S
Journal of virology 2024 May 14;98(5):e0195923
Journal of virology 2024 May 14;98(5):e0195923
Inhibition of the RLR signaling pathway by SARS-CoV-2 ORF7b is mediated by MAVS and abrogated by ORF7b-homologous interfering peptide.
Xiao X, Fu Y, You W, Huang C, Zeng F, Gu X, Sun X, Li J, Zhang Q, Du W, Cheng G, Liu Z, Liu L
Journal of virology 2024 May 14;98(5):e0157323
Journal of virology 2024 May 14;98(5):e0157323
Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells.
Dong M, Zhang T, Liang X, Cheng X, Shi F, Yuan H, Zhang F, Jiang Q, Wang X
Biochemical and biophysical research communications 2024 May 14;708:149815
Biochemical and biophysical research communications 2024 May 14;708:149815
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
Liu J, Huang Y, Qian T, Chen J, Ding Y, Lai Z, Zhong X, Lai M, Zhang H, Wang Y, Wang H, Peng Y
Cell communication and signaling : CCS 2024 May 14;22(1):269
Cell communication and signaling : CCS 2024 May 14;22(1):269
The Rejuvenation and Functional Restoration of Aged Adipose Stem Cells by DUXAP10 Knockdown via the Regulation of the miR-214-3p/RASSF5 Axis.
Ren S, Li C, Xiong H, Wu Q, Wu X, Xiong Z, Dong L, Shu B, Wei W, Ma C, Li X, Chen J
Stem cells translational medicine 2024 May 14;13(5):462-476
Stem cells translational medicine 2024 May 14;13(5):462-476
The role of microRNA-142a in Toxoplasma gondii infection-induced downregulation of Foxp3: implications for adverse pregnancy outcomes.
Zhong Y, Cao Y, Geng X, Yang S, Qian T, Liu C, Chen J
BMC infectious diseases 2024 May 13;24(1):490
BMC infectious diseases 2024 May 13;24(1):490
Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis.
Liu M, Huo X, Li C, Hu Y, Lei H, Wang D, Zhu L, Gu Y, Guo D, Huang L, Deng Y
Acta biochimica et biophysica Sinica 2024 May 11;56(12):1789-1801
Acta biochimica et biophysica Sinica 2024 May 11;56(12):1789-1801
Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop.
Aberle T, Walter A, Piefke S, Hillgärtner S, Wüst HM, Wegner M, Küspert M
International journal of molecular sciences 2024 May 11;25(10)
International journal of molecular sciences 2024 May 11;25(10)
Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles.
Bian X, Yang L, Jiang D, Grippin AJ, Ma Y, Wu S, Wu L, Wang X, Tang Z, Tang K, Pan W, Dong S, Kim BYS, Jiang W, Yang Z, Li C
Nature communications 2024 May 11;15(1):3987
Nature communications 2024 May 11;15(1):3987
Deciphering metabolic heterogeneity in retinoblastoma unravels the role of monocarboxylate transporter 1 in tumor progression.
Tang J, Liu Y, Wang Y, Zhang Z, Nie J, Wang X, Ai S, Li J, Gao Y, Li C, Cheng C, Su S, Chen S, Zhang P, Lu R
Biomarker research 2024 May 11;12(1):48
Biomarker research 2024 May 11;12(1):48
Integration of metabolomics and transcriptomics reveals that Da Chuanxiong Formula improves vascular cognitive impairment via ACSL4/GPX4 mediated ferroptosis.
Lou T, Wu H, Feng M, Liu L, Yang X, Pan M, Wei Z, Zhang Y, Shi L, Qu B, Yang H, Cong S, Chen K, Liu J, Li Y, Jia Z, Xiao H
Journal of ethnopharmacology 2024 May 10;325:117868
Journal of ethnopharmacology 2024 May 10;325:117868
Classical prescription Floris Sophorae Powder treat colorectal cancer by regulating KRAS/MEK-ERK signaling pathway.
Han LY, Yu H, Wang S, Bao YR, Li TJ, Zheng Y, Luo X, Jia MN, Zhang Q, Meng XS
Journal of ethnopharmacology 2024 May 10;325:117805
Journal of ethnopharmacology 2024 May 10;325:117805
Acod1/itaconate activates Nrf2 in pulmonary microvascular endothelial cells to protect against the obesity-induced pulmonary microvascular endotheliopathy.
Zhu L, Wu Z, Liu Y, Ming Y, Xie P, Jiang M, Qi Y
Respiratory research 2024 May 10;25(1):205
Respiratory research 2024 May 10;25(1):205
Single-cell transcriptomic analysis of decidual immune cell landscape in the occurrence of adverse pregnancy outcomes induced by Toxoplasma gondii infection.
Fu T, Wang X, Zhao X, Jiang Y, Liu X, Zhang H, Ren Y, Li Z, Hu X
Parasites & vectors 2024 May 10;17(1):213
Parasites & vectors 2024 May 10;17(1):213
Identification of an Immunodominant B-Cell Epitope in African Swine Fever Virus p30 Protein and Evidence of p30 Antibody-Mediated Antibody Dependent Cellular Cytotoxicity.
Noll JCG, Rani R, Butt SL, Fernandes MHV, do Nascimento GM, Martins M, Caserta LC, Covaleda L, Diel DG
Viruses 2024 May 10;16(5)
Viruses 2024 May 10;16(5)
Minimally invasive vagus nerve stimulation modulates mast cell degranulation via the microbiota-gut-brain axis to ameliorate blood-brain barrier and intestinal barrier damage following ischemic stroke.
Wang Y, Tan Q, Pan M, Yu J, Wu S, Tu W, Li M, Jiang S
International immunopharmacology 2024 May 10;132:112030
International immunopharmacology 2024 May 10;132:112030
LAMP1 controls CXCL10-CXCR3 axis mediated inflammatory regulation of macrophage polarization during inflammatory stimulation.
Ye Y, Li L, Kang H, Wan Z, Zhang M, Gang B, Liu J, Liu G, Gu W
International immunopharmacology 2024 May 10;132:111929
International immunopharmacology 2024 May 10;132:111929
Cadmium exacerbates liver injury by remodeling ceramide metabolism: Multiomics and laboratory evidence.
Xie D, Yan J, Zhang H, Zhang H, Nie G, Zhu X, Li X
The Science of the total environment 2024 May 1;923:171405
The Science of the total environment 2024 May 1;923:171405
Dihydroartemisinin is an inhibitor of trained immunity through Akt/mTOR/HIF1α signaling pathway.
Gao Y, Liu ZZ, Zhang JB, Zhou CK, Zhang JG, Lin XQ, Yin Q, Chen W, Yang YJ
Experimental cell research 2024 May 1;438(1):114052
Experimental cell research 2024 May 1;438(1):114052
Salidroside induces mitochondrial dysfunction and ferroptosis to inhibit melanoma progression through reactive oxygen species production.
Zhang X, Zhang M, Zhang Z, Zhou S
Experimental cell research 2024 May 1;438(1):114034
Experimental cell research 2024 May 1;438(1):114034
Dibutyl phthalate exposure induced mitochondria-dependent ferroptosis by enhancing VDAC2 in zebrafish ZF4 cells.
Hou T, Fan X, Zhang Q, Zhang H, Zhang D, Tao L, Wang Z
Environmental pollution (Barking, Essex : 1987) 2024 May 1;348:123846
Environmental pollution (Barking, Essex : 1987) 2024 May 1;348:123846
Melatonin alleviates glyphosate-induced testosterone synthesis inhibition via targeting mitochondrial function in roosters.
Ren YL, Liang Q, Lian CY, Zhang W, Wang L
Environmental pollution (Barking, Essex : 1987) 2024 May 1;348:123828
Environmental pollution (Barking, Essex : 1987) 2024 May 1;348:123828
Loss of KLF15 impairs endometrial receptivity by inhibiting EMT in endometriosis.
Huang Y, Wang Z, Li B, Ke L, Xiong Y, Zhang Y
The Journal of endocrinology 2024 May 1;261(2)
The Journal of endocrinology 2024 May 1;261(2)
Salvianolic acid B attenuates diabetic nephropathy through alleviating ADORA2B, NALP3 in flammasome, and NFκB activity.
Wang Y, Chang J, Qiao S, Yang Y, Yun C, Li Y, Wang F
Canadian journal of physiology and pharmacology 2024 May 1;102(5):318-330
Canadian journal of physiology and pharmacology 2024 May 1;102(5):318-330
UCP2 overexpression activates SIRT3 to regulate oxidative stress and mitochondrial dynamics induced by myocardial injury.
Geng Z, Chen W, Lu Q, Fu B, Fu X
Archives of biochemistry and biophysics 2024 Mar;753:109918
Archives of biochemistry and biophysics 2024 Mar;753:109918
Role of MAPKs in TGF-β1-induced maturation and mineralization in human osteoblast-like cells.
Wang TH, Watanabe K, Hamada N, Tani-Ishii N
Journal of oral biosciences 2024 Mar;66(1):61-67
Journal of oral biosciences 2024 Mar;66(1):61-67
Integrative analyses of N6-methyladenosine-associated single-nucleotide polymorphisms (m6A-SNPs) identify tumor suppressor gene AK9 in lung cancer.
Hua T, Zhang C, Fu Y, Qin N, Liu S, Chen C, Gong L, Ma H, Ding Y, Wei X, Jin C, Jin C, Zhu M, Zhang E, Dai J, Ma H
Molecular carcinogenesis 2024 Mar;63(3):538-548
Molecular carcinogenesis 2024 Mar;63(3):538-548
lncRNA UCA1 promotes tumor progression by targeting SMARCD3 in cervical cancer.
An L, Dong K, Chi S, Wei S, Zhang J, Yu Z, Zhang Q, Zhang T, Cheng S, Shi R, Jin Z, Zhou X, Zhao Y, Wang H
Molecular carcinogenesis 2024 Mar;63(3):384-399
Molecular carcinogenesis 2024 Mar;63(3):384-399
Genomic sequencing revealed recombination event between clade 1 and clade 2 occurs in circulating varicella-zoster virus in China.
Li J, Wang D, Qi L, Yang Y, Pei J, Dong Y, Wang Y, Yao M, Zhang F, Lei Y, Cheng L, Ye W
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 2024 Mar;55(1):125-132
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 2024 Mar;55(1):125-132
NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica‑induced lung fibrosis.
Zhou H, Zhang Q, Liu C, Fan J, Huang W, Li N, Yang M, Wang H, Xie W, Kong H
International journal of molecular medicine 2024 Mar;53(3)
International journal of molecular medicine 2024 Mar;53(3)
Genome-scale CRISPR-Cas9 screen identifies PAICS as a therapeutic target for EGFR wild-type non-small cell lung cancer.
Li Y, Zhu L, Mao J, Zheng H, Hu Z, Yang S, Mao T, Zhou T, Cao P, Wu H, Wang X, Wang J, Lin F, Shen H
MedComm 2024 Mar;5(3):e483
MedComm 2024 Mar;5(3):e483
KIAA1549 promotes the development and chemoresistance of colorectal cancer by upregulating ERCC2.
Ye F, Xie Y, Lin M, Liu Y, Fang Y, Chen K, Zhang Y, Ding Y
Molecular and cellular biochemistry 2024 Mar;479(3):629-642
Molecular and cellular biochemistry 2024 Mar;479(3):629-642
Tropisetron attenuates neuroinflammation and chronic neuropathic pain via α7nAChR activation in the spinal cord in rats.
Zhang YF, Yu D, Gong XR, Meng C, Lv J, Li Q
The journal of spinal cord medicine 2024 Mar;47(2):277-285
The journal of spinal cord medicine 2024 Mar;47(2):277-285
Cardiac-specific deletion of BRG1 ameliorates ventricular arrhythmia in mice with myocardial infarction.
Li J, Ma ZY, Cui YF, Cui YT, Dong XH, Wang YZ, Fu YY, Xue YD, Tong TT, Ding YZ, Zhu YM, Huang HJ, Zhao L, Lv HZ, Xiong LZ, Zhang K, Han YX, Ban T, Huo R
Acta pharmacologica Sinica 2024 Mar;45(3):517-530
Acta pharmacologica Sinica 2024 Mar;45(3):517-530
Baicalein attenuates rotenone-induced SH-SY5Y cell apoptosis through binding to SUR1 and activating ATP-sensitive potassium channels.
Kong DW, Du LD, Liu RZ, Yuan TY, Wang SB, Wang YH, Lu Y, Fang LH, Du GH
Acta pharmacologica Sinica 2024 Mar;45(3):480-489
Acta pharmacologica Sinica 2024 Mar;45(3):480-489
NADP(+)-dependent isocitrate dehydrogenase as a novel target for altering carbon flux to lipid accumulation and enhancing antioxidant capacity in Tetradesmus obliquus.
Li J, Wang W, Li B, Xue Y, Wang X, Liu S, Hu S, Tang J, Yan B, Li T, Xue J
Bioresource technology 2024 Mar;395:130365
Bioresource technology 2024 Mar;395:130365
Sevoflurane Suppresses Glioma Cell Proliferation, Migration, and Invasion Both In Vitro and In Vivo Partially Via Regulating KCNQ1OT1/miR-146b-5p/STC1 Axis.
Wen J, Ding Y, Zheng S, Li X, Xiao Y
Cancer biotherapy & radiopharmaceuticals 2024 Mar;39(2):105-116
Cancer biotherapy & radiopharmaceuticals 2024 Mar;39(2):105-116
Alginate microspheres encapsulating hox transcript antisense RNA siRNA regulate the Hedgehog-Gli1 pathway to alleviate epidermal growth factor receptor tyrosine kinase inhibitors resistance.
Lu G, Zhong H, Gao J, Zhang Y
Journal of biomaterials applications 2024 Mar;38(8):877-889
Journal of biomaterials applications 2024 Mar;38(8):877-889
Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models.
Chen K, Xu B, Xiao X, Long L, Zhao Q, Fang Z, Tu X, Wang J, Xu J, Wang H
Experimental neurology 2024 Mar;373:114654
Experimental neurology 2024 Mar;373:114654
LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1.
Huang Z, Shen F, Chen J, Xie B, Chen X, Zhao Y, Chen S
Journal of gynecologic oncology 2024 Mar;35(2):e21
Journal of gynecologic oncology 2024 Mar;35(2):e21
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
Chen Y, Zhang YH, Li J, Shi L, Xie JC, Han X, Chen YT, Xiang M, Li BW, Xing HR, Wang JY
Cancer gene therapy 2024 Mar;31(3):364-375
Cancer gene therapy 2024 Mar;31(3):364-375
Mitochondrial-targeting and NIR-responsive Mn(3)O(4)@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis.
Li Y, Yang J, Chen X, Hu H, Lan N, Zhao J, Zheng L
Biomaterials 2024 Mar;305:122449
Biomaterials 2024 Mar;305:122449
SESN1 functions as a new tumor suppressor gene via Toll-like receptor signaling pathway in neuroblastoma.
Hua Z, Chen B, Gong B, Lin M, Ma Y, Li Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14664
CNS neuroscience & therapeutics 2024 Mar;30(3):e14664
Mitochondrial protein CHCHD10 inhibits NDV replication and reduces pathological changes.
Yu X, Jiang H, Li J, Ding J, Wu T, Chen K, Ding Z, Xu X
Veterinary microbiology 2024 Mar;290:109986
Veterinary microbiology 2024 Mar;290:109986
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Wang H, Han S, Xiao J, Fu X, Chen W, Zhuo D
Oncology letters 2024 Mar;27(3):102
Oncology letters 2024 Mar;27(3):102
Research on triamcinolone-loaded thermosensitive chitosan hydrogels for preventing esophageal stricture induced by endoscopic submucosal dissection.
Wang Y, Su Y, Zhu Y, Ni P, Yu T, Yuan T, Sun X, Shan J
International journal of biological macromolecules 2024 Mar;261(Pt 1):129679
International journal of biological macromolecules 2024 Mar;261(Pt 1):129679
Bi-functional KIT-PR1P peptides combine with VEGF to protect ischemic kidney in rats by targeting to Kim-1.
Zhou R, Liu H, Hou X, Liu Q, Sun S, Li X, Cao W, Nie W, Shi C, Chen W
Regenerative therapy 2024 Mar;25:162-173
Regenerative therapy 2024 Mar;25:162-173
Osteopontin-driven partial epithelial-mesenchymal transition governs the development of middle ear cholesteatoma.
Zeng L, Xie L, Hu J, He C, Liu A, Lu X, Zhou W
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):537-554
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):537-554
Lipoteichoic acid restrains macrophage senescence via β-catenin/FOXO1/REDD1 pathway in age-related osteoporosis.
Cheng W, Fu Y, Lin Z, Huang M, Chen Y, Hu Y, Lin Q, Yu B, Liu G
Aging cell 2024 Mar;23(3):e14072
Aging cell 2024 Mar;23(3):e14072
HuR-positive stress granules: Potential targets for age-related osteoporosis.
Huai Y, Wang X, Mao W, Wang X, Zhao Y, Chu X, Huang Q, Ru K, Zhang L, Li Y, Chen Z, Qian A
Aging cell 2024 Mar;23(3):e14053
Aging cell 2024 Mar;23(3):e14053
Ethanol extract of Cyathulae Radix inhibits osteoclast differentiation and bone loss.
Shi L, Ren L, Li J, Liu X, Lu J, Jia L, Xie B, Tang S, Liu W, Zhang J
Chinese journal of natural medicines 2024 Mar;22(3):212-223
Chinese journal of natural medicines 2024 Mar;22(3):212-223
Targeting ZIP8 mediated ferroptosis as a novel strategy to protect against the retinal pigment epithelial degeneration.
Liu Z, Huang J, Li D, Zhang C, Wan H, Zeng B, Tan Y, Zhong F, Liao H, Liu M, Chen ZS, Zou C, Liu D, Qin B
Free radical biology & medicine 2024 Mar;214:42-53
Free radical biology & medicine 2024 Mar;214:42-53
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
Song B, Zhu Y, Zhao Y, Wang K, Peng Y, Chen L, Yu Z, Song B
International wound journal 2024 Mar;21(3):e14481
International wound journal 2024 Mar;21(3):e14481
Physical and social environmental enrichment alleviate ferroptosis and inflammation with inhibition of TLR4/MyD88/p38MAPK pathway in chronic cerebral hypoperfusion rats.
Fan B, Zhang Y, Luo Q, Hao C, Liao W
Brain research bulletin 2024 Mar;208:110897
Brain research bulletin 2024 Mar;208:110897
BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1.
Lin H, Sandkuhler S, Dunlea C, Rodwell-Bullock J, King DH, Johnson GVW
Autophagy 2024 Mar;20(3):577-589
Autophagy 2024 Mar;20(3):577-589
Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA.
Zhu C, Fang X, Liu X, Jiang C, Ren W, Huang W, Jiang Y, Wang D
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119681
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119681
STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.
Wang L, Zhang S, Liu H, Gao L, He L, Chen Y, Zhang J, Yang M, He C
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166997
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166997
DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A(2) mediated lysosomal membrane permeabilization after spinal cord injury.
Chen Y, Zhang H, Jiang L, Cai W, Kuang J, Geng Y, Xu H, Li Y, Yang L, Cai Y, Wang X, Xiao J, Ni W, Zhou K
British journal of pharmacology 2024 Mar;181(5):712-734
British journal of pharmacology 2024 Mar;181(5):712-734
2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1, 4-Dione isolated from Averrhoa carambola L. root inhibits high glucose-induced EMT in HK-2 cells through targeting the regulation of miR-21-5p/Smad7 signaling pathway.
Li J, Pang Q, Huang X, Jiang H, Tang G, Yan H, Guo Y, Yan X, Li L, Zhang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116280
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116280
Ubiquitination of cytoplasmic HMGB1 by RNF186 regulates hepatic lipophagy in non-alcoholic fatty liver disease.
Du J, Ji X, Xu B, Du Q, Li Y, Zhou B, Liu X, Xu Z, Jiang Y, Kou B, Li Z, Cui C, Lin J
Metabolism: clinical and experimental 2024 Mar;152:155769
Metabolism: clinical and experimental 2024 Mar;152:155769
Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene.
Hong W, Xiao T, Lin G, Liu C, Li H, Li Y, Hu H, Wu S, Wang S, Liang Z, Lin T, Liu J, Chen X
Bioorganic chemistry 2024 Mar;144:107113
Bioorganic chemistry 2024 Mar;144:107113
NSUN2 promotes colorectal cancer progression by enhancing SKIL mRNA stabilization.
Zou S, Huang Y, Yang Z, Zhang J, Meng M, Zhang Y, Feng J, Sun R, Li W, Wang W, López JG, Fang L
Clinical and translational medicine 2024 Mar;14(3):e1621
Clinical and translational medicine 2024 Mar;14(3):e1621
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
Hao DJ, Qin Y, Zhou SJ, Dong BH, Yang JS, Zou P, Wang LP, Zhao YT
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
Enhancing Bone Regeneration through CDC20-Loaded ZIF-8 Nanoparticles Wrapped in Erythrocyte Membranes with Targeting Aptamer.
Du Y, Deng T, Cheng Y, Zhao Q, Xia H, Ji Y, Zhang Y, He Q
Advanced healthcare materials 2024 Mar;13(7):e2302725
Advanced healthcare materials 2024 Mar;13(7):e2302725
3D Printed Photothermal Scaffold Sandwiching Bacteria Inside and Outside Improves The Infected Microenvironment and Repairs Bone Defects.
Zhao Y, Kang H, Xia Y, Sun L, Li F, Dai H
Advanced healthcare materials 2024 Mar;13(6):e2302879
Advanced healthcare materials 2024 Mar;13(6):e2302879
Poliumoside protects against type 2 diabetes-related osteoporosis by suppressing ferroptosis via activation of the Nrf2/GPX4 pathway.
Xu CY, Xu C, Xu YN, Du SQ, Dai ZH, Jin SQ, Zheng G, Xie CL, Fang WL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155342
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155342
Gansui Banxia decoction modulates immune-inflammatory homeostasis to ameliorate malignant ascites in rats.
Huo M, Wang T, Li M, Li N, Chen S, Xiu L, Yu X, Liu H, Zhong G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155246
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155246
Potential of Lactobacillus plantarum A56 in relieving food allergy through immunoregulation, antioxidation, and reshaping intestinal microbiota.
Duan C, Ma L, Qin M, Zhang L, Hu S, Liu L, Sun Y, Ma F, Li D
The Journal of nutritional biochemistry 2024 Mar;125:109560
The Journal of nutritional biochemistry 2024 Mar;125:109560
Cypermethrin induces Sertoli cell apoptosis through endoplasmic reticulum-mitochondrial coupling involving IP3R1-GRP75-VDAC1.
Zhang R, Wang XX, Xie JF, Yao TT, Guo QW, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
Reproductive toxicology (Elmsford, N.Y.) 2024 Mar;124:108552
Reproductive toxicology (Elmsford, N.Y.) 2024 Mar;124:108552
Stiffness promotes cell migration, invasion, and invadopodia in nasopharyngeal carcinoma by regulating the WT-CTTN level.
Bao L, Zhong M, Zhang Z, Yu X, You B, You Y, Gu M, Zhang Q, Chen W, Lei W, Hu S
Cancer science 2024 Mar;115(3):836-846
Cancer science 2024 Mar;115(3):836-846
DEAD-box helicase 1 inhibited CD8(+) T cell antitumor activity by inducing PD-L1 expression in hepatocellular carcinoma.
Liu J, Yang T, Luo Y, Ma Z, Yu Z, Zhang L, Liu G, Wen J, Lu G, Zhang G, Zhao Y, Luo W, Li Y, Yang N, Zhou J, Lu Y, Chen S, Zeng X
Cancer science 2024 Mar;115(3):763-776
Cancer science 2024 Mar;115(3):763-776
METTL3-mediated m(6)A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.
Feng ZW, Peng B, Wang SH, Zhao DC, Wang YB, Yang A, Zhan HW, Sheng XY, Xu LH, Ren XJ, Yang F, Geng B, Xia YY
Cellular signalling 2024 Mar;115:111038
Cellular signalling 2024 Mar;115:111038
A comprehensive evaluation of circ_0065214/ miR-188-3p/GPNMB axis in breast cancer.
Wu XX, Zhao YX, Xu SL, Wang LX, Mao JH, Wang B, Yang H
Cellular signalling 2024 Mar;115:111019
Cellular signalling 2024 Mar;115:111019
The impact of LncRNA-SOX2-OT/let-7c-3p/SKP2 Axis on head and neck squamous cell carcinoma progression: Insights from bioinformatics analysis and experimental validation.
Wang D, Zhao X, Li S, Guo H, Li S, Yu D
Cellular signalling 2024 Mar;115:111018
Cellular signalling 2024 Mar;115:111018
Truncated PD1 Engineered Gas-Producing Extracellular Vesicles for Ultrasound Imaging and Subsequent Degradation of PDL1 in Tumor Cells.
Zhang S, Liang Y, Ji P, Zheng R, Lu F, Hou G, Yang G, Yuan L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2305891
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2305891
Lentinan inhibits cell invasion via M2 polarization of tumor-associated macrophages and Wnt/β-catenin signaling in non-small cell lung cancer.
Yang Y, Cheng Y, Mu Y, Tang X, Mu X
Chemical biology & drug design 2024 Mar;103(3):e14507
Chemical biology & drug design 2024 Mar;103(3):e14507
CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner.
Ndzie Noah ML, Mprah R, Wowui PI, Adekunle AO, Adu-Amankwaah J, Tan R, Gong Z, Li T, Fu L, Machuki JO, Zhang S, Sun H
Cell communication and signaling : CCS 2024 Mar 7;22(1):166
Cell communication and signaling : CCS 2024 Mar 7;22(1):166
Dysregulation and antimetastatic function of circLRIG1 modulated by miR-214-3p/LRIG1 axis in bladder carcinoma.
Cheng S, Li C, Liu L, Liu X, Li M, Zhuo J, Wang J, Zheng W, Wang Z
Biology direct 2024 Mar 7;19(1):20
Biology direct 2024 Mar 7;19(1):20
Spinosin inhibits activated hepatic stellate cell to attenuate liver fibrosis by targeting Nur77/ASK1/p38 MAPK signaling pathway.
Lin G, Li W, Hong W, Zhu D, Hu H, Fu J, Gao Y, Chen S, Chai D, Zeng JZ
European journal of pharmacology 2024 Mar 5;966:176270
European journal of pharmacology 2024 Mar 5;966:176270
Psychological stress induces hair regenerative disorders through corticotropin-releasing hormone-mediated autophagy inhibition.
Liang W, Zhao Y, Cai B, Huang Y, Chen X, Ni N, Wang Y, Lin Z, Lin C, Huang K
Biochemical and biophysical research communications 2024 Mar 5;699:149564
Biochemical and biophysical research communications 2024 Mar 5;699:149564
Upregulation of TRPC1 protects against high glucose-induced HUVECs dysfunction by inhibiting oxidative stress.
Qu M, Du L
Biochemical and biophysical research communications 2024 Mar 5;699:149560
Biochemical and biophysical research communications 2024 Mar 5;699:149560
Investigating the Impact of Dimer Interface Mutations on Norrin's Secretion and Norrin/β-Catenin Pathway Activation.
Liu M, Dai E, Yang M, Li S, Fan L, Liu Y, Xiao H, Zhao P, Yang Z
Investigative ophthalmology & visual science 2024 Mar 5;65(3):31
Investigative ophthalmology & visual science 2024 Mar 5;65(3):31
A high-affinity fluorescent probe for human uridine-disphosphate glucuronosyltransferase 1A9 function monitoring under environmental pollutant exposure.
Miao YS, Wang JY, Zhuang RR, Huo XK, Yi ZC, Sun XN, Yu ZL, Tian XG, Ning J, Feng L, Ma XC, Lv X
Journal of hazardous materials 2024 Mar 5;465:133439
Journal of hazardous materials 2024 Mar 5;465:133439
Hub gene ELK3-mediated reprogramming lipid metabolism regulates phenotypic switching of pulmonary artery smooth muscle cells to develop pulmonary arterial hypertension induced by PM(2.5).
Liu Q, Yang Y, Wu M, Wang M, Yang P, Zheng J, Du Z, Pang Y, Bao L, Niu Y, Zhang R
Journal of hazardous materials 2024 Mar 5;465:133190
Journal of hazardous materials 2024 Mar 5;465:133190
Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8(+)T cells.
Hu C, Qiao W, Li X, Ning ZK, Liu J, Dalangood S, Li H, Yu X, Zong Z, Wen Z, Gui J
Cell metabolism 2024 Mar 5;36(3):630-647.e8
Cell metabolism 2024 Mar 5;36(3):630-647.e8
CETSA-MS-based target profiling of anti-aging natural compound quercetin.
Bai L, Deng Z, Xu M, Zhang Z, Guo G, Xue X, Wang S, Yang J, Xia Z
European journal of medicinal chemistry 2024 Mar 5;267:116203
European journal of medicinal chemistry 2024 Mar 5;267:116203
ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice.
Zhuang T, Chen MH, Wu RX, Wang J, Hu XD, Meng T, Wu AH, Li Y, Yang YF, Lei Y, Hu DH, Li YX, Zhang L, Sun AJ, Lu W, Zhang GN, Zuo JL, Ruan CC
Nature communications 2024 Mar 5;15(1):1995
Nature communications 2024 Mar 5;15(1):1995
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
Wu X, Zhang Y, Ji M, Yang W, Deng T, Hou G, Shi L, Xun W
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
N6-methyladenosine-modified CircPSMA7 enhances bladder cancer malignancy through the miR-128-3p/MAPK1 axis.
Yi J, Ma X, Ying Y, Liu Z, Tang Y, Shu X, Sun J, Wu Y, Lu D, Wang X, Luo J, Liu B, Zheng X, Lin Y, Li J, Xie L
Cancer letters 2024 Mar 31;585:216613
Cancer letters 2024 Mar 31;585:216613
Candesartan upregulates angiotensin-converting enzyme 2 in kidneys of male animals by decreased ubiquitination.
Wang P, Ren Z, Wang W, Liu M, Jia Y, Zhang M, Xue Y, Zhang C, Xu J, Wang C, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23537
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23537
RFX1 regulates foam cell formation and atherosclerosis by mediating CD36 expression.
Yang S, Min X, Hu L, Zheng M, Lu S, Zhao M, Jia S
International immunopharmacology 2024 Mar 30;130:111751
International immunopharmacology 2024 Mar 30;130:111751
MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer.
Jiang W, Miao Y, Xing X, Liu S, Xing W, Qian F
Heliyon 2024 Mar 30;10(6):e28172
Heliyon 2024 Mar 30;10(6):e28172
Activation of astrocytes by ANXA2-derived extracellular vesicles from lung cancer cells affects aggressiveness, immunotherapy response and microenvironment of lung cancer.
He M, Xie G, Shen F, Li X
Heliyon 2024 Mar 30;10(6):e27729
Heliyon 2024 Mar 30;10(6):e27729
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx.
Xiang Z, Zhang P, Jia C, Xu R, Cao D, Xu Z, Lu T, Liu J, Wang X, Qiu C, Fu W, Li W, Cheng L, Yang Q, Feng S, Wang L, Zhao Y, Liu X
Bone research 2024 Mar 29;12(1):20
Bone research 2024 Mar 29;12(1):20
Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironment.
Ma Y, Li J, Zhao X, Ji C, Hu W, Ma Y, Qu F, Sun Y, Zhang X
European journal of medical research 2024 Mar 28;29(1):207
European journal of medical research 2024 Mar 28;29(1):207
Dietary chenodeoxycholic acid attenuates high-fat diet-induced growth retardation, lipid accumulation and bile acid metabolism disorder in the liver of yellow catfish Pelteobagrus fulvidraco.
Zheng H, Xu YC, Zhao T, Luo Z, Zhang DG, Song CC, Yu AG, Tan X
The British journal of nutrition 2024 Mar 28;131(6):921-934
The British journal of nutrition 2024 Mar 28;131(6):921-934
Riboflavin Attenuates Fluoride-Induced Testicular Injury via Interleukin 17A-Mediated Classical Pyroptosis.
Li X, Yang J, Luo H, Qiao Y, Zhao L, Cheng C, Fu W, Tan Y, Wang J, Liang C, Zhang J
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6143-6154
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6143-6154
Glutathione Induces Keap1 S-Glutathionylation and Mitigates Oscillating Glucose-Induced β-Cell Dysfunction by Activating Nrf2.
Chen X, Zhou Q, Chen H, Bai J, An R, Zhang K, Zhang X, An H, Zhang J, Wang Y, Li M
Antioxidants (Basel, Switzerland) 2024 Mar 27;13(4)
Antioxidants (Basel, Switzerland) 2024 Mar 27;13(4)
YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS.
Wang J, Zhou Y, Zhang M, Wu Y, Wu Q, Su W, Xu M, Wu J, Zhang M, Shuai J, Tang W, Lv J, Wu M, Xia Z
Cell reports 2024 Mar 26;43(3):113947
Cell reports 2024 Mar 26;43(3):113947
Wnt5a/β-catenin-mediated epithelial-mesenchymal transition: a key driver of subretinal fibrosis in neovascular age-related macular degeneration.
Liu D, Du J, Xie H, Tian H, Lu L, Zhang C, Xu GT, Zhang J
Journal of neuroinflammation 2024 Mar 26;21(1):75
Journal of neuroinflammation 2024 Mar 26;21(1):75
Network pharmacology analysis and experimental validation to explore the mechanism of kaempferol in the treatment of osteoporosis.
Dong Q, Ren G, Li Y, Hao D
Scientific reports 2024 Mar 26;14(1):7088
Scientific reports 2024 Mar 26;14(1):7088
Naoxinqing tablet protects against cerebral ischemic/reperfusion injury by regulating ampkα/NAMPT/SIRT1/PGC-1α pathway.
Sun X, Pan Y, Luo Y, Guo H, Zhang Z, Wang D, Li C, Sun X
Journal of ethnopharmacology 2024 Mar 25;322:117672
Journal of ethnopharmacology 2024 Mar 25;322:117672
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
Zhao J, Luo J, Deng C, Fan Y, Liu N, Cao J, Chen D, Diao Y
Journal of ethnopharmacology 2024 Mar 25;322:117621
Journal of ethnopharmacology 2024 Mar 25;322:117621
Air-Liquid Interface Microfluidic Monitoring Sensor Platform for Studying Autophagy Regulation after PM2.5 Exposure.
Zheng L, Yang Z, Xue Z, Chen M, Zhang Y, Cai S, Zheng K, Dai B, Liu S, Zhuang S, Sui G, Zhang D
ACS sensors 2024 Mar 22;9(3):1178-1187
ACS sensors 2024 Mar 22;9(3):1178-1187
A Pilot Study on a Possible Mechanism behind Olfactory Dysfunction in Parkinson's Disease: The Association of TAAR1 Downregulation with Neuronal Loss and Inflammation along Olfactory Pathway.
Zhang MX, Hong H, Shi Y, Huang WY, Xia YM, Tan LL, Zhao WJ, Qiao CM, Wu J, Zhao LP, Huang SB, Jia XB, Shen YQ, Cui C
Brain sciences 2024 Mar 22;14(4)
Brain sciences 2024 Mar 22;14(4)
TROP2 is highly expressed in triple-negative breast cancer CTCs and is a potential marker for epithelial mesenchymal CTCs.
Liao Q, Zhang R, Ou Z, Ye Y, Zeng Q, Wang Y, Wang A, Chen T, Chai C, Guo B
Molecular therapy. Oncology 2024 Mar 21;32(1):200762
Molecular therapy. Oncology 2024 Mar 21;32(1):200762
Supplementation of Nicotinic Acid and Its Derivatives Up-Regulates Cellular NAD(+) Level Rather than Nicotinamide Derivatives in Cultured Normal Human Epidermal Keratinocytes.
Oyama T, Yamamoto T, Kameda T, Kamiya T, Abe H, Abe T, Tanuma SI
Life (Basel, Switzerland) 2024 Mar 20;14(3)
Life (Basel, Switzerland) 2024 Mar 20;14(3)
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Huang W, Wang L, Huang Z, Sun Z, Zheng B
Respiratory research 2024 Mar 2;25(1):110
Respiratory research 2024 Mar 2;25(1):110
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling.
Huang Y, Wu Z, Peng Z, Liu A, Yuan W, Han D, Peng J
BMC cancer 2024 Mar 18;24(1):345
BMC cancer 2024 Mar 18;24(1):345
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species.
Chen S, Puri A, Bell B, Fritsche J, Palacios HH, Balch M, Sprunger ML, Howard MK, Ryan JJ, Haines JN, Patti GJ, Davis AA, Jackrel ME
Nature communications 2024 Mar 18;15(1):2436
Nature communications 2024 Mar 18;15(1):2436
NAP-seq reveals multiple classes of structured noncoding RNAs with regulatory functions.
Liu S, Huang J, Zhou J, Chen S, Zheng W, Liu C, Lin Q, Zhang P, Wu D, He S, Ye J, Liu S, Zhou K, Li B, Qu L, Yang J
Nature communications 2024 Mar 18;15(1):2425
Nature communications 2024 Mar 18;15(1):2425
Mechanistic Insights into the Inhibition of a Common CTLA-4 Gene Mutation in the Cytoplasmic Domain.
Xu J, Zhang Y, Shen L, Du L, Xue H, Wu B, OuYang B
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Wang W, Ma Z, Feng X, Ren J, Sun S, Shao Y, Zhang W, Yang X, Zhang J, Jing X
Arthritis research & therapy 2024 Mar 16;26(1):71
Arthritis research & therapy 2024 Mar 16;26(1):71
Low-intensity pulsed ultrasound delays the progression of osteoarthritis by regulating the YAP-RIPK1-NF-κB axis and influencing autophagy.
Pan C, Lu F, Hao X, Deng X, Liu J, Sun K, Hou W, Shang X, Chi R, Guo F, Xu T
Journal of translational medicine 2024 Mar 16;22(1):286
Journal of translational medicine 2024 Mar 16;22(1):286
Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway.
Zhang W, Wu F
Scientific reports 2024 Mar 16;14(1):6392
Scientific reports 2024 Mar 16;14(1):6392
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
Zhao Z, Han W, Huang G, He Y, Zuo X, Hong L
Experimental cell research 2024 Mar 15;436(2):113974
Experimental cell research 2024 Mar 15;436(2):113974
FTO-mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway.
Wang DX, Bao SY, Song NN, Chen WZ, Ding XQ, Walker RJ, Fang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23436
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23436
Polystyrene microplastic-induced extracellular vesicles cause kidney-related effects in the crosstalk between tubular cells and fibroblasts.
Wang YL, Huang CC, Zheng CM, Liu WC, Lee YH, Chiu HW
Ecotoxicology and environmental safety 2024 Mar 15;273:116098
Ecotoxicology and environmental safety 2024 Mar 15;273:116098
Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA.
Brewer A, Sathe G, Pflug BE, Clarke RG, Macartney TJ, Sapkota GP
iScience 2024 Mar 15;27(3):109302
iScience 2024 Mar 15;27(3):109302
CircTBC1D22A inhibits the progression of colorectal cancer through autophagy regulated via miR-1825/ATG14 axis.
Sun J, Wu H, Luo J, Qiu Y, Li Y, Xu Y, Liu L, Liu X, Zhang Q
iScience 2024 Mar 15;27(3):109168
iScience 2024 Mar 15;27(3):109168
Minimally invasive delivery of human umbilical cord-derived mesenchymal stem cells by an injectable hydrogel via Diels-Alder click reaction for the treatment of intrauterine adhesions.
Hu S, Dai Y, Xin L, Zheng X, Ye Z, Zhang S, Ma L
Acta biomaterialia 2024 Mar 15;177:77-90
Acta biomaterialia 2024 Mar 15;177:77-90
A pyrimidine metabolism-related signature for prognostic and immunotherapeutic response prediction in hepatocellular carcinoma by integrating analyses.
Zhang S, Qin O, Wu S, Xu H, Huang W, Hailiang S
Aging 2024 Mar 15;16(6):5545-5566
Aging 2024 Mar 15;16(6):5545-5566
Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis.
Wang F, Liu X, Huang F, Zhou Y, Wang X, Song Z, Wang S, Wang X, Shi D, Ruan G, Ji X, Zhang E, Tan Z, Ye Y, Wang C, Zhu J, Wang W
eLife 2024 Mar 15;12
eLife 2024 Mar 15;12
FTO-mediated autophagy inhibition promotes non-small cell lung cancer progression by reducing the stability of SESN2 mRNA.
Wang K, Mei Z, Zheng M, Liu X, Li D, Wang H
Heliyon 2024 Mar 15;10(5):e27571
Heliyon 2024 Mar 15;10(5):e27571
IDI1 inhibits the cGAS-Sting signaling pathway in hepatocellular carcinoma.
Fu L, Ding H, Bai Y, Cheng L, Hu S, Guo Q
Heliyon 2024 Mar 15;10(5):e27205
Heliyon 2024 Mar 15;10(5):e27205
Pro-tumorigenic activity of PYCR1 in gastric cancer through regulating the PI3K/AKT signaling.
Xiao H, Huang J, Wu H, Li Y, Wang Y
Heliyon 2024 Mar 15;10(5):e26883
Heliyon 2024 Mar 15;10(5):e26883
Discovery of Novel N-(Anthracen-9-ylmethyl) Benzamide Derivatives as ZNF207 Inhibitors Promising in Treating Glioma.
Zhang M, Ding Y, Gao M, Lu X, Tan J, Yu F, Gu C, Gu L, Ren X, Hao C, Ming L, Xu K, Mao W, Jin Y, Zhang M, You L, Wang Z, Sun Y, Jiang J, Yang Y, Zhang D, Tang X
Journal of medicinal chemistry 2024 Mar 14;67(5):3909-3934
Journal of medicinal chemistry 2024 Mar 14;67(5):3909-3934
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
Cen Q, Chen J, Guo J, Chen M, Wang H, Wu S, Zhang H, Xie X, Li Y
Journal of translational medicine 2024 Mar 14;22(1):278
Journal of translational medicine 2024 Mar 14;22(1):278
Transcriptome analysis of Edwardsiella piscicida during intracellular infection reveals excludons are involved with the activation of a mitochondrion-like energy generation program.
Lanza A, Kimura S, Hirono I, Yoshitake K, Kinoshita S, Asakawa S
mBio 2024 Mar 13;15(3):e0352623
mBio 2024 Mar 13;15(3):e0352623
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway.
Wan X, Wang L, Khan MA, Peng L, Zhang K, Sun X, Yi X, Wang Z, Chen K
Cell death discovery 2024 Mar 11;10(1):129
Cell death discovery 2024 Mar 11;10(1):129
ATG9A as a potential diagnostic marker of intervertebral disc degeneration: Inferences from experiments and bioinformatics analysis incorporating sc-RNA-seq data.
Tang X, Lin S, Luo H, Wang L, Zhong J, Xiong J, Lv H, Zhou F, Wan Z, Cao K
Gene 2024 Mar 1;897:148084
Gene 2024 Mar 1;897:148084
Two novel angiotensin I-converting enzyme inhibitory peptides from garlic protein: In silico screening, stability, antihypertensive effects in vivo and underlying mechanisms.
Xiang L, Zheng Z, Guo X, Bai R, Zhao R, Chen H, Qiu Z, Qiao X
Food chemistry 2024 Mar 1;435:137537
Food chemistry 2024 Mar 1;435:137537
Sphingosine kinase 1-specific inhibitor PF543 reduces goblet cell metaplasia of bronchial epithelium in an acute asthma model.
Sudhadevi T, Ackerman SJ, Jafri A, Basa P, Ha AW, Natarajan V, Harijith A
American journal of physiology. Lung cellular and molecular physiology 2024 Mar 1;326(3):L377-L392
American journal of physiology. Lung cellular and molecular physiology 2024 Mar 1;326(3):L377-L392
Veronica linariifolia subsp. dilatata ameliorates LPS-induced acute lung injury by attenuating endothelial cell barrier dysfunction via EGFR/Akt/ZO-1 pathway.
Wu H, Wu L, Yu W, Gu C, Li Y, Chen K, Zhang L, Qian F
Journal of ethnopharmacology 2024 Mar 1;321:117545
Journal of ethnopharmacology 2024 Mar 1;321:117545
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
Mode of action exploration of reproductive toxicity induced by bisphenol S using human normal ovarian epithelial cells through ERβ-MAPK signaling pathway.
Yu M, Yang Z, Zhou Y, Guo W, Tian L, Zhang L, Li X, Chen J
Ecotoxicology and environmental safety 2024 Mar 1;272:116037
Ecotoxicology and environmental safety 2024 Mar 1;272:116037
PPP2R1B abolishes colorectal cancer liver metastasis and sensitizes Oxaliplatin by inhibiting MAPK/ERK signaling pathway.
Liu W, Tang J, Gao W, Sun J, Liu G, Zhou J
Cancer cell international 2024 Mar 1;24(1):90
Cancer cell international 2024 Mar 1;24(1):90
miR-345-3p Modulates M1/M2 Macrophage Polarization to Inhibit Inflammation in Bone Infection via Targeting MAP3K1 and NF-κB Pathway.
Dai Y, Yi X, Huang Y, Qian K, Huang L, Hu J, Liu Y
Journal of immunology (Baltimore, Md. : 1950) 2024 Mar 1;212(5):844-854
Journal of immunology (Baltimore, Md. : 1950) 2024 Mar 1;212(5):844-854
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
Zhou C, Li D, He J, Luo T, Liu Y, Xue Y, Huang J, Zheng L, Li J
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
Influenza A virus infection disrupts the function of syncytiotrophoblast cells and contributes to adverse pregnancy outcomes.
Wang J, Liu W, Zhuang Y, Yang J, Zhao Y, Hong A, Du J, Kong H, Wang J, Jiang Y, Wang Y
Journal of medical virology 2024 Jun;96(6):e29687
Journal of medical virology 2024 Jun;96(6):e29687
ID2 promotes tumor progression and metastasis in thyroid cancer.
Deng Z, Xu M, Ding Z, Kong J, Liu J, Zhang Z, Cao P
Endocrine 2024 Jun;84(3):1051-1063
Endocrine 2024 Jun;84(3):1051-1063
Lentinan mitigates pemetrexed chemoresistance by the PI3K/Akt pathway in non-small cell lung cancer.
Tian P, Du D, Yang L, Zhou N, Tao L
Cell biochemistry and biophysics 2024 Jun;82(2):1421-1431
Cell biochemistry and biophysics 2024 Jun;82(2):1421-1431
miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure.
Xu G, Xu Y, Zhang Y, Kao G, Li J
Cell biochemistry and biophysics 2024 Jun;82(2):1193-1201
Cell biochemistry and biophysics 2024 Jun;82(2):1193-1201
Neuronal small extracellular vesicles carrying miR-181c-5p contribute to the pathogenesis of epilepsy by regulating the protein kinase C-δ/glutamate transporter-1 axis in astrocytes.
Ma L, Wu Q, You Y, Zhang P, Tan D, Liang M, Huang Y, Gao Y, Ban Y, Chen Y, Yuan J
Glia 2024 Jun;72(6):1082-1095
Glia 2024 Jun;72(6):1082-1095
Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating BNIP3-Mediated mitochondrial dysfunction.
Li X, Luo W, Tang Y, Wu J, Zhang J, Chen S, Zhou L, Tao Y, Tang Y, Wang F, Huang Y, Jose PA, Guo L, Zeng C
Redox biology 2024 Jun;72:103129
Redox biology 2024 Jun;72:103129
Albizzia chinensis (Osbeck) Merr extract YS ameliorates ethanol-induced acute gastric ulcer injury in rats by regulating NRF2 signaling pathway.
Tang B, Li L, Yu Y, Wang G, Ma S, Yu S, Zhang J
Animal models and experimental medicine 2024 Jun;7(3):275-282
Animal models and experimental medicine 2024 Jun;7(3):275-282
Norisoboldine, a Natural Alkaloid from Lindera aggregata (Sims) Kosterm, Promotes Osteogenic Differentiation via S6K1 Signaling Pathway and Prevents Bone Loss in OVX Mice.
Li S, Yan W, Sun K, Miao J, Liu Z, Xu J, Wang X, Li B, Zhang Q
Molecular nutrition & food research 2024 Jun;68(12):e2400193
Molecular nutrition & food research 2024 Jun;68(12):e2400193
MiR-5189-3p Suppresses cell Proliferation, Invasion and Migration Through Targeting EIF5A2 in Laryngeal Squamous Cell Carcinoma.
Lou D, Jia Q, Zhang H, Wang J, Liu L, Liu Z, Jia X, Wang J, Shan C
Biochemical genetics 2024 Jun;62(3):1603-1616
Biochemical genetics 2024 Jun;62(3):1603-1616
Environmental Enrichment Improves the Recognition Memory in Adult Mice Following Social Isolation via Downregulation of Kv4.2 Potassium Channels.
Shang Q, Dong YB, Xu L, Yang JH, Li JW, Yu WY, Sun J, Gao X, Huang Y, Zhang XQ
Molecular neurobiology 2024 Jun;61(6):3742-3752
Molecular neurobiology 2024 Jun;61(6):3742-3752
A Disintegrin and Metalloproteinase-8 Protects Against Erastin-Induced Neuronal Ferroptosis via Activating Nrf2/HO-1/FTH1 Signaling Pathway.
Qian Z, Zhang Q, Li P, Li Y, Zhang Y, Li R, Zhao T, Xia M, Chen Y, Hong X
Molecular neurobiology 2024 Jun;61(6):3490-3502
Molecular neurobiology 2024 Jun;61(6):3490-3502
Acupuncture Alleviates Chronic Ischemic White Matter Injury in SHR Rats via JNK-NMDAR Circuit.
Dong A, Gao Z, Wang H, Wu R, Wang W, Jin X, Ji Y, Yang F, Zhu T, Jiang Z, Xu Y, Guo J, Ji L
Molecular neurobiology 2024 Jun;61(6):3144-3160
Molecular neurobiology 2024 Jun;61(6):3144-3160
METTL3-mediated pre-miR-665/DLX3 m(6)A methylation facilitates the committed differentiation of stem cells from apical papilla.
Gu T, Guo R, Fang Y, Xiao Y, Chen L, Li N, Ge XK, Shi Y, Wu J, Yan M, Yu J, Li Z
Experimental & molecular medicine 2024 Jun;56(6):1426-1438
Experimental & molecular medicine 2024 Jun;56(6):1426-1438
Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade.
Zhu K, Ma X, Guan X, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R
Journal of molecular histology 2024 Jun;55(3):241-251
Journal of molecular histology 2024 Jun;55(3):241-251
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes-associated HLA-B39 allotypes.
Amarajeewa AWP, Özcan A, Mukhtiar A, Ren X, Wang Q, Ozbek P, Garstka MA, Serçinoğlu O
European journal of immunology 2024 Jun;54(6):e2350683
European journal of immunology 2024 Jun;54(6):e2350683
Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.
Zhang J, Wang Y, Hou S, Chi X, Ding D, Xue M, Zhang M, Wang J, Shuai J, Sun H, Gao Q, Kang C
Oncology reports 2024 Jun;51(6)
Oncology reports 2024 Jun;51(6)
DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway.
Lin J, Li B, Xu Q, Liu YS, Kang YL, Wang X, Wang Y, Lei Y, Bai YL, Li XM, Zhou J
Journal of endocrinological investigation 2024 Jun;47(6):1531-1544
Journal of endocrinological investigation 2024 Jun;47(6):1531-1544
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Lu JS, Wang JH, Han K, Li N
Inflammation 2024 Jun;47(3):975-988
Inflammation 2024 Jun;47(3):975-988
FBXO22 is a potential therapeutic target for recurrent chondrosarcoma.
Xin B, Chen H, Zhu Z, Guan Q, Bai G, Yang C, Zou W, Gao X, Li L, Liu T
Journal of bone oncology 2024 Jun;46:100605
Journal of bone oncology 2024 Jun;46:100605
Quantitative systems pharmacology modeling of HER2-positive metastatic breast cancer for translational efficacy evaluation and combination assessment across therapeutic modalities.
Zhou YT, Chu JH, Zhao SH, Li GL, Fu ZY, Zhang SJ, Gao XH, Ma W, Shen K, Gao Y, Li W, Yin YM, Zhao C
Acta pharmacologica Sinica 2024 Jun;45(6):1287-1304
Acta pharmacologica Sinica 2024 Jun;45(6):1287-1304
High-dimensional deconstruction of ovarian cancer at single-cell precision reveals HEBP2 that reshape the TIME and drive carboplatin resistance.
Yang B, Dai M
Translational oncology 2024 Jun;44:101917
Translational oncology 2024 Jun;44:101917
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
Zhao J, Shen J, Mao L, Yang T, Liu J, Hongbin S
Oncogene 2024 Jun;43(27):2104-2114
Oncogene 2024 Jun;43(27):2104-2114
Beclin 1 Haploinsufficiency Ameliorates High-Fat Diet-Induced Myocardial Injury via Inhibiting Alternative Mitophagy.
Zeng X, Sun J, Li F, Peng L, Zhang C, Jiang X, Zha L, Rathinasabapathy A, Ren J, Yu Z, Wang L, Liu X
Antioxidants & redox signaling 2024 Jun;40(16-18):906-925
Antioxidants & redox signaling 2024 Jun;40(16-18):906-925
Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway.
Wang X, Li X, Ma X, Zhang L, Han T, Zhang D
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4183-4194
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4183-4194
The mechanism of action of myricetin against lung adenocarcinoma based on bioinformatics, in silico and in vitro experiments.
Hao P, Zhang C, Bian H, Li Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4089-4104
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4089-4104
Circ_0027791 contributes to the growth and immune evasion of hepatocellular carcinoma via the miR-496/programmed cell death ligand 1 axis in an m6A-dependent manner.
Yu F, Fang P, Fang Y, Chen D
Environmental toxicology 2024 Jun;39(6):3721-3733
Environmental toxicology 2024 Jun;39(6):3721-3733
Mice harboring the T316N variant in the GABA(A)R γ(2) subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway.
Jiang YL, Xia L, Zhao JJ, Zhou HM, Mi D, Wang X, Wang YY, Song CG, Jiang W
Experimental neurology 2024 Jun;376:114775
Experimental neurology 2024 Jun;376:114775
MARK1 regulates dendritic spine morphogenesis and cognitive functions in vivo.
Kelly-Castro EC, Shear R, Dindigal AH, Bhagwat M, Zhang H
Experimental neurology 2024 Jun;376:114752
Experimental neurology 2024 Jun;376:114752
PANoptosis subtypes predict prognosis and immune efficacy in gastric cancer.
Liu Z, Sun L, Peng X, Zhu J, Wu C, Zhu W, Huang C, Zhu Z
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):799-815
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):799-815
CircMYBL1 suppressed acquired resistance to osimertinib in non-small-cell lung cancer.
Li Y, Wang N, Huang Y, He S, Bao M, Wen C, Wu L
Cancer genetics 2024 Jun;284-285:34-42
Cancer genetics 2024 Jun;284-285:34-42
Effect of continuous positive airway pressure treatment on Th17/Treg imbalance in patients with obstructive sleep apnea and a preliminary study on its mechanism.
Shen C, Zong D, Peng Y, Zhou L, Liu T, Ouyang R
Sleep & breathing = Schlaf & Atmung 2024 Jun;28(3):1231-1243
Sleep & breathing = Schlaf & Atmung 2024 Jun;28(3):1231-1243
SNORD99 promotes endometrial cancer development by inhibiting GSDMD-mediated pyroptosis through 2'-O-methylation modification.
Xian JY, Wu W, Chen X, Bao HJ, Zhang S, Sheng XJ, Chen S
Journal of cellular and molecular medicine 2024 Jun;28(12):e18500
Journal of cellular and molecular medicine 2024 Jun;28(12):e18500
ATF3 is involved in rSjP40-mediated inhibition of HSCs activation in Schistosoma japonicum-infected mice.
Li J, Zhang J, Zhang B, Chen G, Huang M, Xu B, Zhu D, Chen J, Duan Y, Gao W
Journal of cellular and molecular medicine 2024 Jun;28(12):e18458
Journal of cellular and molecular medicine 2024 Jun;28(12):e18458
Atorvastatin causes developmental and behavioral toxicity in yellowstripe goby (Mugilogobius chulae) embryos/larvae via disrupting lipid metabolism and autophagy processes.
Zhao Y, Wang Y, Ren J, Gong W, Nie X, Peng Y, Li J, Duan C
Aquatic toxicology (Amsterdam, Netherlands) 2024 Jun;271:106909
Aquatic toxicology (Amsterdam, Netherlands) 2024 Jun;271:106909
Bioinformatics analysis and experimental verification of NLRX1 as a prognostic factor for esophageal squamous cell carcinoma.
Zhou L, Gan L, Sun C, Chu A, Yang M, Liu Z
Oncology letters 2024 Jun;27(6):264
Oncology letters 2024 Jun;27(6):264
Metabolic reprogramming driven by METTL1-mediated tRNA m7G modification promotes acquired anlotinib resistance in oral squamous cell carcinoma.
Chen J, Zhou Q, Li S, Ling R, Zhao Y, Chen D, Wang A, Cao Y
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:28-39
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:28-39
Comprehensive analysis of ATP6V1s family member, ATP6V1C2, with prognostic and drug development values in colorectal cancer.
Li J, Li J, Chen J, Cao W, Chen B
Pathology, research and practice 2024 Jun;258:155357
Pathology, research and practice 2024 Jun;258:155357
Anti-pancreatic cancer activity of cassane diterpenoids isolated from the seeds of Caesalpinia sappan mediated by autophagy activation via ROS/AMPK/mTORC1 pathway.
Su J, Wang DS, Hu GX, Liu YY, Hu M, Chen Y, Wang QQ, Yan RC, Wu Y, Li YJ, Ma K, Qi YY, Ding LF, Wu XD
Phytochemistry 2024 Jun;222:114105
Phytochemistry 2024 Jun;222:114105
The chemerin-CMKLR1 axis in keratinocytes impairs innate host defense against cutaneous Staphylococcus aureus infection.
Chen Y, Song Y, Wang Z, Lai Y, Yin W, Cai Q, Han M, Cai Y, Xue Y, Chen Z, Li X, Chen J, Li M, Li H, He R
Cellular & molecular immunology 2024 Jun;21(6):533-545
Cellular & molecular immunology 2024 Jun;21(6):533-545
The therapeutic role of SSEA3(+) human umbilical cord blood mononuclear cells in ischemic stroke model.
Xiao D, Li F, Zhang K, Liu G, Wang Y, Liu H
Neuroscience research 2024 Jun;203:42-50
Neuroscience research 2024 Jun;203:42-50
METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer.
Yuan XN, Shao YC, Guan XQ, Liu Q, Chu MF, Yang ZL, Li H, Zhao S, Tian YH, Zhang JW, Wei L
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119716
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119716
Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis.
Cai H, Zhao J, Zhang Q, Wu H, Sun Y, Guo F, Zhou Y, Qin G, Xia W, Zhao Y, Liang X, Yin S, Qin Y, Li D, Wu H, Ren D
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167183
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167183
EGFL6 promotes endometrial cancer cell migration and proliferation.
Garrett AA, Bai S, Cascio S, Gupta N, Yang D, Buckanovich RJ
Gynecologic oncology 2024 Jun;185:75-82
Gynecologic oncology 2024 Jun;185:75-82
Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation.
Feng S, Xie X, Li J, Xu X, Chen C, Zou G, Lin G, Huang T, Hu R, Ran T, Han L, Zhang Q, Li Y, Zhao X
Hepatology international 2024 Jun;18(3):1040-1052
Hepatology international 2024 Jun;18(3):1040-1052
Polysaccharides from Dendrobium officinale delay diabetic kidney disease interstitial fibrosis through LncRNA XIST/TGF-β1.
Zhang Y, Deng Y, Yang Y, Yang Z, Yin Y, Xie J, Ding J, Shang Y, Zha Y, Yuan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116636
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116636
CREB1 Silencing Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis Through Reducing RPL9 Expression and Blocking NF-κB Signaling.
Jian X, Yang D, Wang L, Wang H
Journal of cardiovascular translational research 2024 Jun;17(3):570-584
Journal of cardiovascular translational research 2024 Jun;17(3):570-584
Pravastatin promotes type 2 diabetes vascular calcification through activating intestinal Bacteroides fragilis to induce macrophage M1 polarization.
Chen C, Liang ZF, He YQ, Li AQ, Gao Y, Pan QW, Cao JS
Journal of diabetes 2024 Jun;16(6):e13514
Journal of diabetes 2024 Jun;16(6):e13514
Unraveling Key m(6)A Modification Regulators Signatures in Postmenopausal Osteoporosis through Bioinformatics and Experimental Verification.
Feng ZW, Xiao HF, Wang XW, Niu YK, Zhao DC, Tian C, Wang SH, Peng B, Yang F, Geng B, Guo MG, Sheng XY, Xia YY
Orthopaedic surgery 2024 Jun;16(6):1418-1433
Orthopaedic surgery 2024 Jun;16(6):1418-1433
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
Zhao W, Zhao B, Meng X, Li B, Wang Y, Yu F, Fu C, Yu X, Li X, Dai C, Wang J, Gao H, Cheng M
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.
Li Y, Liu C, Han X, Sheng R, Bao L, Lei L, Wu Y, Li Q, Zhang Y, Zhang J, Wang W, Zhang Y, Li S, Wang C, Wei X, Wang J, Peng Z, Xu Y, Si S
Bioorganic chemistry 2024 Jun;147:107364
Bioorganic chemistry 2024 Jun;147:107364
Carrimycin inhibits coronavirus replication by decreasing the efficiency of programmed -1 ribosomal frameshifting through directly binding to the RNA pseudoknot of viral frameshift-stimulatory element.
Li H, Li J, Li J, Li H, Wang X, Jiang J, Lei L, Sun H, Tang M, Dong B, He W, Si S, Hong B, Li Y, Song D, Peng Z, Che Y, Jiang JD
Acta pharmaceutica Sinica. B 2024 Jun;14(6):2567-2580
Acta pharmaceutica Sinica. B 2024 Jun;14(6):2567-2580
Fangchinoline induces antiviral response by suppressing STING degradation.
Wang J, Xie F, Jia X, Wang X, Kong L, Li Y, Liang X, Zhang M, He Y, Feng W, Luo T, Wang Y, Xu A
Journal of pharmaceutical analysis 2024 Jun;14(6):100972
Journal of pharmaceutical analysis 2024 Jun;14(6):100972
Solamargine improves the therapeutic efficacy of anti-PD-L1 in lung adenocarcinoma by inhibiting STAT1 activation.
Liu Q, Xu M, Qiu M, Yu J, Wang Q, Zhou Y, Lin Q, Cai X, Yang L, Zhao H, Zhao C, Xie X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155538
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155538
Moracin D suppresses cell growth and induces apoptosis via targeting the XIAP/PARP1 axis in pancreatic cancer.
Zhong X, Ke X, Yang H, Ye X, Li C, Pan J, Ran W, Wang F, Cui H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155527
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155527
Celastrol induced the autophagy of spermatogonia cells contributed to tripterygium glycosides-related testicular injury.
Cui DX, Niu ZC, Tang X, Cai CZ, Xu DQ, Fu RJ, Liu WJ, Wang YW, Tang YP
Reproductive toxicology (Elmsford, N.Y.) 2024 Jun;126:108604
Reproductive toxicology (Elmsford, N.Y.) 2024 Jun;126:108604
Quantitative proteomic analysis of circulating exosomes reveals the mechanism by which Triptolide protects against collagen-induced arthritis.
Liu X, Liu X, Wang H, Chen M, Zhang G, Ren D, Zhang N, Wei W
Immunity, inflammation and disease 2024 Jun;12(6):e1322
Immunity, inflammation and disease 2024 Jun;12(6):e1322
Overexpression of macrophage migration inhibitory factor protects against pressure overload-induced cardiac hypertrophy through regulating the miR-29b-3p/HBP1 axis.
Wen L, Chen W, Zhu C, Li J, Zhou J, Zhang M, Zhang W, Xue Q
Physiological reports 2024 Jun;12(12):e16022
Physiological reports 2024 Jun;12(12):e16022
Mussel-inspired immunomodulatory and osteoinductive dual-functional hydroxyapatite nanoplatform for promoting bone regeneration.
Qin D, Zhao Y, Cheng R, Liu Y, Guo S, Sun L, Guo Y, Hao F, Zhao B
Journal of nanobiotechnology 2024 Jun 8;22(1):320
Journal of nanobiotechnology 2024 Jun 8;22(1):320
Dang-Gui-Si-Ni decoction facilitates wound healing in diabetic foot ulcers by regulating expression of AGEs/RAGE/TGF-β/Smad2/3.
Zhang S, Xu Y, Zhang Junior C, Chen X, Zhu J
Archives of dermatological research 2024 Jun 7;316(7):338
Archives of dermatological research 2024 Jun 7;316(7):338
Comprehensive Urinary Proteome Profiling Analysis Identifies Diagnosis and Relapse Surveillance Biomarkers for Bladder Cancer.
Chang Q, Chen Y, Yin J, Wang T, Dai Y, Wu Z, Guo Y, Wang L, Zhao Y, Yuan H, Song D, Zhang L
Journal of proteome research 2024 Jun 7;23(6):2241-2252
Journal of proteome research 2024 Jun 7;23(6):2241-2252
Triple Blockade of Oncogenic RAS Signaling Using KRAS and MEK Inhibitors in Combination with Irradiation in Pancreatic Cancer.
Wang X, Breuer J, Garbe S, Giordano F, Brossart P, Feldmann G, Bisht S
International journal of molecular sciences 2024 Jun 6;25(11)
International journal of molecular sciences 2024 Jun 6;25(11)
M2 macrophage-derived exosomes promote angiogenesis and improve cardiac function after myocardial infarction.
Guo H, Li Z, Xiao B, Huang R
Biology direct 2024 Jun 6;19(1):43
Biology direct 2024 Jun 6;19(1):43
Oridonin represses lung cancer cell proliferation and migration by modulating AFAP1-AS1/IGF2BP1.
Chen M, Shen Y
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jun 5;70(6):108-113
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jun 5;70(6):108-113
GSNOR overexpression enhances CAR-T cell stemness and anti-tumor function by enforcing mitochondrial fitness.
Niu Q, Zhang H, Wang F, Xu X, Luo Y, He B, Shi M, Jiang E, Feng X
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jun 5;32(6):1875-1894
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jun 5;32(6):1875-1894
Chlormequat Chloride Inhibits TM3 Leydig Cell Growth via Ferroptosis-Initiated Inflammation.
Wang X, Kang C, Guo W, Zhang H, Xiao Q, Hao W
Cells 2024 Jun 5;13(11)
Cells 2024 Jun 5;13(11)
Ethnopharmacological study on Adenosma buchneroides Bonati inhibiting inflammation via the regulation of TLR4/MyD88/NF-κB signaling pathway.
Shi Y, Zhang X, Pei S, Wang Y
Natural products and bioprospecting 2024 Jun 4;14(1):36
Natural products and bioprospecting 2024 Jun 4;14(1):36
HDAC1/2/3-mediated downregulation of neurogranin is involved in cognitive impairment in offspring exposed to maternal subclinical hypothyroidism.
Yu X, Guo J, Song Y, Wei B, Shi Y, Zhao Y, Zhao Z, Gao Q, Wang B, Sun M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jun 30;38(12):e23736
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jun 30;38(12):e23736
Label-free Raman imaging for screening of anti-inflammatory function food.
Zeng Q, Peng Y, Zhou X, Zhang J, Yang Y, Xu X, Guan B, Zhang Y, Hu X, Chen X
Food chemistry: X 2024 Jun 30;22:101297
Food chemistry: X 2024 Jun 30;22:101297
Fraxinellone alleviates colitis-related intestinal fibrosis by blocking the circuit between PD-1(+) Th17 cells and fibroblasts.
Xu Y, Zheng C, Jiang P, Ji S, Ullah S, Zhao Y, Su D, Xu G, Zhang M, Zou X
International immunopharmacology 2024 Jun 30;135:112298
International immunopharmacology 2024 Jun 30;135:112298
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
Tian X, Li J, Liu S, Dong Q, Fu Y, Luo R, Sun Y, Guo L, Lu Q, Ye C, Liu J, Fu S, Qiu Y
Heliyon 2024 Jun 30;10(12):e33161
Heliyon 2024 Jun 30;10(12):e33161
The effect and mechanism of palmar ginseng in type 2 diabetic cognitive impairment.
Yong S, Yuhan Z, Shanshan C, Xin W, Leilei S, Liu J
Heliyon 2024 Jun 30;10(12):e32525
Heliyon 2024 Jun 30;10(12):e32525
Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches.
Lyu S, Zhang T, Peng P, Cao D, Ma L, Yu Y, Dong Y, Qi X, Wei C
Investigative ophthalmology & visual science 2024 Jun 3;65(6):13
Investigative ophthalmology & visual science 2024 Jun 3;65(6):13
Inhibition of CC chemokine receptor 1 ameliorates osteoarthritis in mouse by activating PPAR-γ.
Xu H, Chen S, Meng C, He Y, Huang XJ, You HB
Molecular medicine (Cambridge, Mass.) 2024 Jun 3;30(1):74
Molecular medicine (Cambridge, Mass.) 2024 Jun 3;30(1):74
Interleukin-22 receptor 1-mediated stimulation of T-type Ca(2+) channels enhances sensory neuronal excitability through the tyrosine-protein kinase Lyn-dependent PKA pathway.
Cai H, Chen S, Sun Y, Zheng T, Liu Y, Tao J, Zhang Y
Cell communication and signaling : CCS 2024 Jun 3;22(1):307
Cell communication and signaling : CCS 2024 Jun 3;22(1):307
Sorcin Inhibits Mitochondrial Apoptosis by Interacting with STAT3 via NF-κB Pathway.
Li Y, Tian M, Pires Sanches JG, Zhang Q, Hou L, Zhang J
International journal of molecular sciences 2024 Jun 29;25(13)
International journal of molecular sciences 2024 Jun 29;25(13)
Oncogenic functions and therapeutic potentials of targeted inhibition of SMARCAL1 in small cell lung cancer.
Sun BB, Wang GZ, Han SC, Yang FY, Guo H, Liu J, Liu YT, Zhou GB
Cancer letters 2024 Jun 28;592:216929
Cancer letters 2024 Jun 28;592:216929
Qixian granule inhibits ferroptosis in vascular endothelial cells by modulating TRPML1 in the lysosome to prevent postmenopausal atherosclerosis.
Zhang M, Mao C, Dai Y, Xu X, Wang X
Journal of ethnopharmacology 2024 Jun 28;328:118076
Journal of ethnopharmacology 2024 Jun 28;328:118076
JinChan YiShen TongLuo Formula ameliorate mitochondrial dysfunction and apoptosis in diabetic nephropathy through the HIF-1α-PINK1-Parkin pathway.
Qiyan Zheng, Zhang X, Guo J, Wang Y, Jiang Y, Li S, Liu YN, Liu WJ
Journal of ethnopharmacology 2024 Jun 28;328:117863
Journal of ethnopharmacology 2024 Jun 28;328:117863
NFIC mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to represses malignant phenotype of non-small cell lung cancer cells.
Shi K, Chen Y, Liu R, Fu X, Guo H, Gao T, Wang S, Dou L, Wang J, Wu Y, Yu J, Yu H
Cancer cell international 2024 Jun 28;24(1):223
Cancer cell international 2024 Jun 28;24(1):223
Oxidative stress-induced EGR1 upregulation promotes NR4A3-mediated nucleus pulposus cells apoptosis in intervertebral disc degeneration.
Zheng SK, Zhao XK, Wu H, He DW, Xiong L, Cheng XG
Aging 2024 Jun 28;16(12):10216-10238
Aging 2024 Jun 28;16(12):10216-10238
Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs.
Yuan J, Li L, Fan Y, Xu X, Huang X, Shi J, Zhang C, Shi L, Wang Y
European journal of histochemistry : EJH 2024 Jun 27;68(3)
European journal of histochemistry : EJH 2024 Jun 27;68(3)
Ameliorated Effects of Fucoidan on Dextran Sulfate Sodium-Induced Ulcerative Colitis and Accompanying Anxiety and Depressive Behaviors in Aged C57BL/6 Mice.
Li S, Qian Q, Xie Y, Wu Z, Yang H, Yin Y, Cui Y, Li X
Journal of agricultural and food chemistry 2024 Jun 26;72(25):14199-14215
Journal of agricultural and food chemistry 2024 Jun 26;72(25):14199-14215
Impact of Abl2/Arg deficiency on anxiety and depressive behaviors in mice.
Yao X, Chen R, Chen H, Koleske A, Xiao X
Behavioural brain research 2024 Jun 25;468:115022
Behavioural brain research 2024 Jun 25;468:115022
Targeted inhibition of DHODH is synergistic with BCL2 blockade in HGBCL with concurrent MYC and BCL2 rearrangement.
Liu L, Mo W, Chen M, Qu Y, Wang P, Liang Y, Yan X
BMC cancer 2024 Jun 25;24(1):761
BMC cancer 2024 Jun 25;24(1):761
M(6)A demethylase FTO-stabilized exosomal circBRCA1 alleviates oxidative stress-induced granulosa cell damage via the miR-642a-5p/FOXO1 axis.
Zhu X, Li W, Lu M, Shang J, Zhou J, Lin L, Liu Y, Xing J, Zhang M, Zhao S, Lu J, Shi X
Journal of nanobiotechnology 2024 Jun 25;22(1):367
Journal of nanobiotechnology 2024 Jun 25;22(1):367
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Wang G, Ma X, Huang W, Wang S, Lou A, Wang J, Tu Y, Cui W, Zhou W, Zhang W, Li Y, Geng S, Meng Y, Li X
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
Lei LM, Li FX, Lin X, Xu F, Shan SK, Guo B, Zheng MH, Tang KX, Wang Y, Xu QS, Ouyang WL, Duan JY, Wu YY, Cao YC, Zhou ZA, He SY, Wu YL, Chen X, Lin ZJ, Pan Y, Yuan LQ, Li ZH
Journal of nanobiotechnology 2024 Jun 23;22(1):361
Journal of nanobiotechnology 2024 Jun 23;22(1):361
Succinate promotes pulmonary fibrosis through GPR91 and predicts death in idiopathic pulmonary fibrosis.
He Y, Han Y, Zou L, Yao T, Zhang Y, Lv X, Jiang M, Long L, Li M, Cheng X, Jiang G, Peng Z, Tao L, Meng J, Xie W
Scientific reports 2024 Jun 22;14(1):14376
Scientific reports 2024 Jun 22;14(1):14376
Intracellular magnetic hyperthermia reverses sorafenib resistance in hepatocellular carcinoma through its action on signaling pathways.
Li H, Ye Z, Wang X, Yuan J, Guo J, Liu C, Yan B, Fan H, Lyu Y, Liu X
iScience 2024 Jun 21;27(6):110029
iScience 2024 Jun 21;27(6):110029
LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition.
Wang X, Hou Y, Lyu Y, Zhou J, Zhang X, Hassani MA, Huang D, Zhao Z, Zhou D, Xie F, Zhang X, Yan J
iScience 2024 Jun 21;27(6):109851
iScience 2024 Jun 21;27(6):109851
Proangiogenic effect and underlying mechanism of holmium oxide nanoparticles: a new biomaterial for tissue engineering.
Luo Y, Zheng Y, Chen Z, Mo M, Xie J, Zhou X, Wu Y, Yang Q, Zheng M, Hu X, Chen L, Lan Z
Journal of nanobiotechnology 2024 Jun 21;22(1):357
Journal of nanobiotechnology 2024 Jun 21;22(1):357
A prominent role of LncRNA H19 in H. pylori CagA induced DNA damage response and cell malignancy.
He X, Huang T, Wang Q, Bao L, Wang Z, Song H, Li Y, Zhou J, Zhao Y, Xie Y
Scientific reports 2024 Jun 20;14(1):14185
Scientific reports 2024 Jun 20;14(1):14185
Reciprocal regulation between RACGAP1 and AR contributes to endocrine therapy resistance in prostate cancer.
Wang J, Liu H, Yu Z, Zhou Q, Sun F, Han J, Gao L, Dou B, Zhang H, Fu J, Jia W, Chen W, Hu J, Han B
Cell communication and signaling : CCS 2024 Jun 19;22(1):339
Cell communication and signaling : CCS 2024 Jun 19;22(1):339
Heparin-Functionalized Bioactive Glass to Harvest Endogenous Growth Factors for Pulp Regeneration.
Wu J, Li J, Mao S, Li B, Zhu L, Jia P, Huang G, Yang X, Xu L, Qiu D, Wang S, Dong Y
ACS applied materials & interfaces 2024 Jun 19;16(24):30715-30727
ACS applied materials & interfaces 2024 Jun 19;16(24):30715-30727
Immune- and metabolism-related gene signature analysis uncovers the prognostic and immune microenvironments of hepatocellular carcinoma.
Gu Y, Ma E, Jiang S, Shan Z, Xia G, Ma R, Fu J, Wang Z
Journal of cancer research and clinical oncology 2024 Jun 19;150(6):311
Journal of cancer research and clinical oncology 2024 Jun 19;150(6):311
Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.
Xian S, Li Y, Bai L, Tang S, Meng Z, Wen H, Huang F, Zeng Z
Frontiers in bioscience (Landmark edition) 2024 Jun 18;29(6):219
Frontiers in bioscience (Landmark edition) 2024 Jun 18;29(6):219
Activation of kappa opioid receptor suppresses post-traumatic osteoarthritis via sequestering STAT3 on the plasma membrane.
Liu H, Huang R, Zhuo Z, Zhang X, Wu L, Guo Z, Wen F, An L, Yuan H, Zhang Y, Xu Y
Cell communication and signaling : CCS 2024 Jun 18;22(1):335
Cell communication and signaling : CCS 2024 Jun 18;22(1):335
Chlorobenzoquinones Aggravate RSL3-Induced Ferroptosis in ROS-Dependent Manner.
Yu X, Chen S, Wang H
Chemical research in toxicology 2024 Jun 17;37(6):1035-1043
Chemical research in toxicology 2024 Jun 17;37(6):1035-1043
A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Kumar A, Gok MO, Nguyen KN, Connor OM, Reese ML, Wideman JG, Muñoz-Gómez SA, Friedman JR
Current biology : CB 2024 Jun 17;34(12):2606-2622.e9
Current biology : CB 2024 Jun 17;34(12):2606-2622.e9
Exposure to polystyrene nanoplastics induces hepatotoxicity involving NRF2-NLRP3 signaling pathway in mice.
Wen Y, Deng S, Wang B, Zhang F, Luo T, Kuang H, Kuang X, Yuan Y, Huang J, Zhang D
Ecotoxicology and environmental safety 2024 Jun 15;278:116439
Ecotoxicology and environmental safety 2024 Jun 15;278:116439
Integrated component identification, network pharmacology, and experimental verification revealed mechanism of Dendrobium officinale Kimura et Migo against lung cancer.
Zhao Y, Zhu S, Li Y, Niu X, Shang G, Zhou X, Yin J, Bao B, Cao Y, Cheng F, Li Z, Wang R, Yao W
Journal of pharmaceutical and biomedical analysis 2024 Jun 15;243:116077
Journal of pharmaceutical and biomedical analysis 2024 Jun 15;243:116077
CRISPR/Cas9-based genome-wide screening for metastasis ability identifies FCGR1A regulating the metastatic process of ovarian cancer by targeting LSP1.
Qi Y, Zhu W, Mo K, Jiang H
Journal of cancer research and clinical oncology 2024 Jun 15;150(6):306
Journal of cancer research and clinical oncology 2024 Jun 15;150(6):306
New strategy to treat spinal cord injury: Nafamostat mesilate suppressed NLRP3-mediated pyroptosis during acute phase.
Lou Y, Li Z, Zheng H, Yuan Z, Li W, Zhang J, Shen W, Gao Y, Ran N, Kong X, Feng S
International immunopharmacology 2024 Jun 15;134:112190
International immunopharmacology 2024 Jun 15;134:112190
Study on the molecular mechanisms of Liuwei Dihuang decoction against aging-related cognitive impairment based on network pharmacology and experimental verification.
OuYang Y, Chen B, Yi J, Zhou S, Liu Y, Tian F, Zeng F, Xiao L, Liu B
Heliyon 2024 Jun 15;10(11):e32526
Heliyon 2024 Jun 15;10(11):e32526
Oncogenic and immunological role of EDIL3 in human tumours: From pan-cancer analysis to validation in gastric cancer.
Ke B, Jin P, Wang XJ, Liu N, Liang H, Zhang RP
Heliyon 2024 Jun 15;10(11):e32291
Heliyon 2024 Jun 15;10(11):e32291
Qingfei mixture mitigates immunosuppression of tumor microenvironment in non-small cell lung cancer by blocking stat1/Ido1-mediated tryptophan-kynurenine pathway.
Chen Z, Ding YH, Shao L, Ji XM, Qian X, Zhang AQ
Heliyon 2024 Jun 15;10(11):e32260
Heliyon 2024 Jun 15;10(11):e32260
ANGPTL3 diminishes the resistance of ovarian cancer to paclitaxel by blocking the PI3K-AKT-mTOR signaling pathway.
Wu D, Liu J, Yang X, Wu Z, Wang T, Xiao M
Heliyon 2024 Jun 15;10(11):e31520
Heliyon 2024 Jun 15;10(11):e31520
Chlamydia trachomatis T3SS Effector CT622 Induces Proinflammatory Cytokines Through TLR2/TLR4-Mediated MAPK/NF-κB Pathways in THP-1 Cells.
Lei W, Wen Y, Yang Y, Liu S, Li Z
The Journal of infectious diseases 2024 Jun 14;229(6):1637-1647
The Journal of infectious diseases 2024 Jun 14;229(6):1637-1647
LINC08148 promotes the caveola-mediated endocytosis of Zika virus through upregulating transcription of Src.
Huo Z, Zhu X, Peng Q, Chen C, Yang X, Huang C, Xiang Y, Tian Q, Liu J, Liu C, Zhang P
Journal of virology 2024 Jun 13;98(6):e0170523
Journal of virology 2024 Jun 13;98(6):e0170523
Transmissible gastroenteritis virus induces inflammatory responses via RIG-I/NF-κB/HIF-1α/glycolysis axis in intestinal organoids and in vivo.
Zhang Y, Yang N, Li Y, Tan C, Cai Y, Rui X, Liu Y, Fu Y, Liu G
Journal of virology 2024 Jun 13;98(6):e0046124
Journal of virology 2024 Jun 13;98(6):e0046124
Pseudolaric Acid B Targets CD147 to Selectively Kill Acute Myeloid Leukemia Cells.
Zou S, Parfenova E, Vrdoljak N, Minden MD, Spagnuolo PA
International journal of molecular sciences 2024 Jun 13;25(12)
International journal of molecular sciences 2024 Jun 13;25(12)
ROS-responsive MSC-derived Exosome Mimetics Carrying MHY1485 Alleviate Renal Ischemia Reperfusion Injury through Multiple Mechanisms.
Qian Z, Zhang X, Huang J, Niu X, Zhu C, Tai Z, Zhu Q, Chen Z, Zhu T, Wu G
ACS omega 2024 Jun 11;9(23):24853-24863
ACS omega 2024 Jun 11;9(23):24853-24863
HNRNPA2B1 stabilizes NFATC3 levels to potentiate its combined actions with FOSL1 to mediate vasculogenic mimicry in GBM cells.
Wang H, Shi Y, Zhou X, Zhang L, Yang A, Zhou D, Ma T
Cell biology and toxicology 2024 Jun 11;40(1):44
Cell biology and toxicology 2024 Jun 11;40(1):44
Ciprofol alleviates remifentanil-induced hyperalgesia by regulating α2GABAARs, NR2B, and P-CaMKIIα levels in the spinal cord and hippocampus.
Yang Y, Yang C, Shi Y, Tang C, Wang H, Tan M, Xing R, Gao C, Zhang M, Xie Y
The Journal of pharmacy and pharmacology 2024 Jun 1;76(6):736-745
The Journal of pharmacy and pharmacology 2024 Jun 1;76(6):736-745
16α-OHE1 alleviates hypoxia-induced inflammation and myocardial damage via the activation of β2-Adrenergic receptor.
Zhou Y, Yin Z, Cui J, Wang C, Fu T, Adu-Amankwaah J, Fu L, Zhou X
Molecular and cellular endocrinology 2024 Jun 1;587:112200
Molecular and cellular endocrinology 2024 Jun 1;587:112200
Ultrasound Microbubble-Stimulated miR-145-5p Inhibits Malignant Behaviors of Breast Cancer Cells by Targeting ACTG1.
Ren L, Wang L, Yi X, Tan Y, Yi L, He J, Li D
Ultrasound quarterly 2024 Jun 1;40(2):136-143
Ultrasound quarterly 2024 Jun 1;40(2):136-143
Exposure to nicotine regulates prostaglandin E2 secretion and autophagy of granulosa cells to retard follicular maturation in mammals.
Zhou X, He Y, Quan H, Yang J, Li S, Jiang Y, Li J, Yuan X
Ecotoxicology and environmental safety 2024 Jun 1;277:116358
Ecotoxicology and environmental safety 2024 Jun 1;277:116358
Co-exposure to fluoride and sulfur dioxide induces abnormal enamel mineralization in rats via the FGF9-mediated MAPK signaling pathway.
Lv Y, Yao J, Wang Y, Bai G, Lin C, Tu C
Environmental research 2024 Jun 1;250:118527
Environmental research 2024 Jun 1;250:118527
ARID3A enhances chemoresistance of pancreatic cancer via inhibiting PTEN-induced ferroptosis.
Mao X, Xu J, Xiao M, Liang C, Hua J, Liu J, Wang W, Yu X, Meng Q, Shi S
Redox biology 2024 Jul;73:103200
Redox biology 2024 Jul;73:103200
O-GlcNAcylation regulates the stability of transferrin receptor (TFRC) to control the ferroptosis in hepatocellular carcinoma cells.
Zhou X, Wang Y, Li X, Zhou J, Yang W, Wang X, Jiao S, Zuo W, You Z, Ying W, Wu C, Bao J
Redox biology 2024 Jul;73:103182
Redox biology 2024 Jul;73:103182
The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation.
Schmidt AL, Kremp M, Aratake T, Cui S, Lin Y, Zhong X, Lu QR, Zhang C, Qiu M, Aberle T, Wegner M
Glia 2024 Jul;72(7):1304-1318
Glia 2024 Jul;72(7):1304-1318
Postbiotics Prepared Using Lactobacillus reuteri Ameliorates Ethanol-Induced Liver Injury by Regulating the FXR/SHP/SREBP-1c Axis.
Liu C, Cai T, Cheng Y, Bai J, Li M, Gu B, Huang M, Fu W
Molecular nutrition & food research 2024 Jul;68(14):e2300927
Molecular nutrition & food research 2024 Jul;68(14):e2300927
Chidamide enhances T-cell-mediated anti-tumor immune function by inhibiting NOTCH1/NFATC1 signaling pathway in ABC-type diffuse large B-cell lymphoma.
Li L, Yang W, Pan Y, Ye R, Wang Y, Li S, Jiang H, Zhang Q, Wang X, Yan J
Leukemia & lymphoma 2024 Jul;65(7):895-910
Leukemia & lymphoma 2024 Jul;65(7):895-910
SIRT3-Mediated Deacetylation of SDHA Rescues Mitochondrial Bioenergetics Contributing to Neuroprotection in Rotenone-Induced PD Models.
Shen Y, Wang X, Nan N, Fu X, Zeng R, Yang Y, Xian S, Shi J, Wu Q, Zhou S
Molecular neurobiology 2024 Jul;61(7):4402-4420
Molecular neurobiology 2024 Jul;61(7):4402-4420
Inhibiting Caveolin-1-Related Akt/mTOR Signaling Pathway Protects Against N-methyl-D-Aspartate Receptor Activation-Mediated Dysfunction of Blood-Brain Barrier in vitro.
Huang F, Mao F, Nong W, Gong Z, Lao D, Huang W
Molecular neurobiology 2024 Jul;61(7):4166-4177
Molecular neurobiology 2024 Jul;61(7):4166-4177
Targeting HMGCS1 restores chemotherapy sensitivity in acute myeloid leukemia.
Zhou C, Li J, Sun X, Zhao L, Zhan H, Liang H, Fang P, Zhang T, He Q, Du J, Zeng H
Blood science (Baltimore, Md.) 2024 Jul;6(3):e00192
Blood science (Baltimore, Md.) 2024 Jul;6(3):e00192
Effects of tetrahedral DNA nanostructures on the treatment of osteoporosis.
Cui W, Yang X, Dou Y, Du Y, Ma X, Hu L, Lin Y
Cell proliferation 2024 Jul;57(7):e13625
Cell proliferation 2024 Jul;57(7):e13625
Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.
Zeng H, Yang X, Liao K, Zuo X, Liang L, He D, Ju R, Wang B, Yuan J
Experimental & molecular medicine 2024 Jul;56(7):1655-1666
Experimental & molecular medicine 2024 Jul;56(7):1655-1666
Gingipains may be one of the key virulence factors of Porphyromonas gingivalis to impair cognition and enhance blood-brain barrier permeability: An animal study.
Li F, Ma C, Lei S, Pan Y, Lin L, Pan C, Li Q, Geng F, Min D, Tang X
Journal of clinical periodontology 2024 Jul;51(7):818-839
Journal of clinical periodontology 2024 Jul;51(7):818-839
A novel LINC02321 promotes cell proliferation and decreases cisplatin sensitivity in bladder cancer by regulating RUVBL2.
Lu C, Gao H, Li H, Luo N, Fan S, Li X, Deng R, He D, Zhao H
Translational oncology 2024 Jul;45:101962
Translational oncology 2024 Jul;45:101962
Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.
Zhao W, Hu X, Chen Z, Li X
DNA and cell biology 2024 Jul;43(7):331-340
DNA and cell biology 2024 Jul;43(7):331-340
Epstein-Barr virus causes vascular abnormalities in epithelial malignancies through upregulating ANXA3-HIF-1α-VEGF pathway.
Chen Y, Di M, Tang Y, Zhao J, Wang Q, Guo Z, Li Y, Ouyang D, Yang J, Chen H, Wang Y, Weng D, Pan Q, Xiang T, Xia J
Oncogene 2024 Jul;43(28):2143-2159
Oncogene 2024 Jul;43(28):2143-2159
Prenatal exposure to low-dose bisphenol A disrupts hippocampal DNA methylation and demethylation in male rat offspring.
Wang Y, Guo Y, Ren J, Liu Q, Wang C
Toxicology and industrial health 2024 Jul;40(7):376-386
Toxicology and industrial health 2024 Jul;40(7):376-386
TLQP-21 facilitates diabetic wound healing by inducing angiogenesis through alleviating high glucose-induced injuries on endothelial progenitor cells.
Fang Y, Zhu Y, Zhang M, Ying H, Xing Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4993-5004
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4993-5004
TFEB ameliorates DEHP-induced neurotoxicity by activating GAL3/TRIM16 axis dependent lysophagy and alleviating lysosomal dysfunction.
Xing H, Xu P, Ma Y, Li T, Zhang Y, Ding X, Liu L, Keerman M, Niu Q
Environmental toxicology 2024 Jul;39(7):3779-3789
Environmental toxicology 2024 Jul;39(7):3779-3789
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway.
Liu F, Feng Q, Yang M, Yang Y, Nie J, Wang S
Phytotherapy research : PTR 2024 Jul;38(7):3594-3606
Phytotherapy research : PTR 2024 Jul;38(7):3594-3606
Exosomes derived from vMIP-II-Lamp2b gene-modified M2 cells provide neuroprotection by targeting the injured spinal cord, inhibiting chemokine signals and modulating microglia/macrophage polarization in mice.
Fu GQ, Wang YY, Xu YM, Bian MM, Zhang L, Yan HZ, Gao JX, Li JL, Chen YQ, Zhang N, Ding SQ, Wang R, Li JY, Hu JG, Lü HZ
Experimental neurology 2024 Jul;377:114784
Experimental neurology 2024 Jul;377:114784
Activation of Wnt signaling mitigates blood-brain barrier disruption by inhibiting vesicular transcytosis after traumatic brain injury in mice.
Zhang Y, Xu J, Li P, Luo B, Tang H
Experimental neurology 2024 Jul;377:114782
Experimental neurology 2024 Jul;377:114782
Spinal histamine H4 receptor mediates chronic pruritus via p-ERK in acetone-ether-water (AEW)-induced dry skin mice.
Wang TT, Li ZY, Hu DD, Xu XY, Song NJ, Li GQ, Zhang L
Experimental dermatology 2024 Jul;33(7):e15128
Experimental dermatology 2024 Jul;33(7):e15128
USP36 inhibits apoptosis by deubiquitinating cIAP1 and survivin in colorectal cancer cells.
Gao B, Qiao Y, Zhu S, Yang N, Zou SS, Liu YJ, Chen J
The Journal of biological chemistry 2024 Jul;300(7):107463
The Journal of biological chemistry 2024 Jul;300(7):107463
SHED-exos promote saliva secretion by suppressing p-ERK1/2-mediated apoptosis in glandular cells.
Chu WX, Ding C, Du ZH, Wei P, Wang YX, Ge XJ, Yu GY
Oral diseases 2024 Jul;30(5):3066-3080
Oral diseases 2024 Jul;30(5):3066-3080
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Zhang GD, Wang MM, Su Y, Fang H, Xue XL, Liu HK, Su Z
Journal of inorganic biochemistry 2024 Jul;256:112574
Journal of inorganic biochemistry 2024 Jul;256:112574
Ginkgolic acids induce liver injury in mice through cell cycle arrest and immune stress under specific condition.
Yang Z, Fang X, Zhang Y, Bai Y, Zhao L, Zhou X
Toxicon : official journal of the International Society on Toxinology 2024 Jul;245:107788
Toxicon : official journal of the International Society on Toxinology 2024 Jul;245:107788
Silibinin attenuates TGF-β2-induced fibrogenic changes in human trabecular meshwork cells by targeting JAK2/STAT3 and PI3K/AKT signaling pathways.
Wu X, Liang J, Liu J, Huang Y, Zhang L, Liu X, Guo J, Zhang M, Chen Y, Wang J
Experimental eye research 2024 Jul;244:109939
Experimental eye research 2024 Jul;244:109939
Enhanced breast cancer treatment using phototherapy and RNS therapy with macrophage membrane-coated liposomes.
Wang F, Li C, Xu X, Zhang W, He Z
Colloids and surfaces. B, Biointerfaces 2024 Jul;239:113961
Colloids and surfaces. B, Biointerfaces 2024 Jul;239:113961
6-Thioguanine inhibits severe fever with thrombocytopenia syndrome virus through suppression of EGR1.
Jiang N, He Y, Wu J, You Q, Zhang R, Cheng M, Liu B, Cai Y, Lyu R, Wu Z
Antiviral research 2024 Jul;227:105916
Antiviral research 2024 Jul;227:105916
Inonotus obliquus (Chaga) against HFD/STZ-induced glucolipid metabolism disorders and abnormal renal functions by regulating NOS-cGMP-PDE5 signaling pathway.
Feng Y, Liu J, Gong L, Han Z, Zhang Y, Li R, Liao H
Chinese journal of natural medicines 2024 Jul;22(7):619-631
Chinese journal of natural medicines 2024 Jul;22(7):619-631
FUDNC1-dependent mitophagy ameliorate motor neuron death in an amyotrophic lateral sclerosis mouse model.
Guo X, Zhang Z, Gu J, Ke P, Liu J, Meng Y, Zheng W, Que W, Fan R, Luo J, Xiao F
Neurobiology of disease 2024 Jul;197:106534
Neurobiology of disease 2024 Jul;197:106534
SH-Alb inhibits phenotype remodeling of pro-fibrotic macrophage to attenuate liver fibrosis through SIRT3-SOD2 axis.
Wu N, Ma S, Ding H, Cao H, Liu T, Tian M, Liu Q, Bian H, Yu Z, Liu C, Wang L, Feng Y, Wu H, Qi J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116919
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116919
Astaxanthin alleviates fibromyalgia pain and depression via NLRP3 inflammasome inhibition.
Zhao L, Tao X, Wang K, Song Y, Zhang B, Yang L, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116856
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116856
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
Dai S, Wang Q, Lyu Y, Chen Z, Liu X, Zhao G, Zhang H
Thoracic cancer 2024 Jul;15(19):1477-1489
Thoracic cancer 2024 Jul;15(19):1477-1489
LncRNA ZFPM2-AS1 promotes phyllodes tumor progression by binding to CDC42 and inhibiting STAT1 activation.
He S, Huang G, Lei R, Jia R, He Z, Chen J, Huang H, Huang Z, Yilihamu A, Li X, Zhuang Z, Han M, Chen X, Huang D, Nie Y
Acta pharmaceutica Sinica. B 2024 Jul;14(7):2942-2958
Acta pharmaceutica Sinica. B 2024 Jul;14(7):2942-2958
LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.
Xu Y, Qiu Z, Chen J, Huang L, Zhang J, Lin J
Drug delivery and translational research 2024 Jul;14(7):2003-2018
Drug delivery and translational research 2024 Jul;14(7):2003-2018
Baicalin reduces chronic stress-induced breast cancer metastasis via directly targeting β2-adrenergic receptor.
Jia Q, Zhou Y, Song L, Shi X, Jiang X, Tao R, Wang A, Wu Y, Wei Z, Zhang Y, Li X, Lu Y
Journal of pharmaceutical analysis 2024 Jul;14(7):100934
Journal of pharmaceutical analysis 2024 Jul;14(7):100934
MCM8 promotes gastric cancer progression through RPS15A and predicts poor prognosis.
Ding L, Sun M, Sun Y, Li J, Zhang Z, Dang S, Zhang J, Yang B, Dai Y, Zhou Q, Zhou D, Li E, Peng S, Li G
Cancer medicine 2024 Jul;13(13):e7424
Cancer medicine 2024 Jul;13(13):e7424
The dual role of 20(S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis.
Ruan Y, Ren G, Wang M, Lv W, Shimizu K, Zhang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155699
Essential oil from Cinnamomum cassia Presl bark regulates macrophage polarization and ameliorates lipopolysaccharide-induced acute lung injury through TLR4/MyD88/NF-κB pathway.
Liu F, Yang Y, Dong H, Zhu Y, Feng W, Wu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155651
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155651
Ginsenoside Rg5 inhibits glioblastoma by activating ferroptosis via NR3C1/HSPB1/NCOA4.
Zhang G, Hu J, Li A, Zhang H, Guo Z, Li X, You Z, Wang Y, Jing Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155631
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155631
Celastrol mediates CAV1 to attenuate pro-tumorigenic effects of senescent cells.
Zhang S, Zhu N, Shi YN, Zeng Q, Zhang CJ, Li HF, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155614
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155614
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism.
Gao L, Zhang AP, Fu L, Li QW, Qin XM, Zhao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155594
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155594
Resveratrol regulates Thoc5 to improve maternal immune activation-induced autism-like behaviors in adult mouse offspring.
Zeng X, Fan L, Li M, Qin Q, Pang X, Shi S, Zheng D, Jiang Y, Wang H, Wu L, Liang S
The Journal of nutritional biochemistry 2024 Jul;129:109638
The Journal of nutritional biochemistry 2024 Jul;129:109638
Bone morphogenetic protein 4 derived from the cerebrospinal fluid in patients with postherpetic neuralgia induces allodynia via the crosstalk between microglia and astrocyte.
Chen K, Wei X, Zhang W, Wang R, Wang Y, Yang L
Brain, behavior, and immunity 2024 Jul;119:836-850
Brain, behavior, and immunity 2024 Jul;119:836-850
Upregulated miR-374a-5p drives psoriasis pathogenesis through WIF1 downregulation and Wnt5a/NF-κB activation.
Ma J, Gan L, Chen H, Chen L, Hu Y, Luan C, Chen K, Zhang J
Cellular signalling 2024 Jul;119:111171
Cellular signalling 2024 Jul;119:111171
Microglial uptake of hADSCs-Exo mitigates neuroinflammation in ICH.
Zhao L, Li J
Cellular signalling 2024 Jul;119:111146
Cellular signalling 2024 Jul;119:111146
Brain Metastasis from EGFR-Mutated Non-Small Cell Lung Cancer: Secretion of IL11 from Astrocytes Up-Regulates PDL1 and Promotes Immune Escape.
Tang M, Xu M, Wang J, Liu Y, Liang K, Jin Y, Duan W, Xia S, Li G, Chu H, Liu W, Wang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(26):e2306348
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(26):e2306348
The HSP90AA1 gene is involved in heat stress responses and its functional genetic polymorphisms are associated with heat tolerance in Holstein cows.
Hu L, Fang H, Abbas Z, Luo H, Brito LF, Wang Y, Xu Q
Journal of dairy science 2024 Jul;107(7):5132-5149
Journal of dairy science 2024 Jul;107(7):5132-5149
PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells.
Vijayakumar A, Majumder M, Yin S, Brobbey C, Karam J, Howley B, Howe PH, Berto S, Madan LK, Gan W, Palanisamy V
Nucleic acids research 2024 Jul 8;52(12):7225-7244
Nucleic acids research 2024 Jul 8;52(12):7225-7244
Mitochondria-Targeted Natural Antioxidant Nanosystem for Diabetic Vascular Calcification Therapy.
Li J, Lan T, Guo Q, Zhang C, Lu X, Hu X, Shen X, Zhang Y
Biomacromolecules 2024 Jul 8;25(7):4329-4343
Biomacromolecules 2024 Jul 8;25(7):4329-4343
Uric acid-lowering effect of harpagoside and its protective effect against hyperuricemia-induced renal injury in mice.
Fu Q, Zhang JJ, Zhu QF, Yu LL, Wang F, Li J, He X, Ao JL, Xu GB, Wei MC, Liao XJ, Liao SG
Biochemical and biophysical research communications 2024 Jul 5;716:150038
Biochemical and biophysical research communications 2024 Jul 5;716:150038
CALU promotes lung adenocarcinoma progression by enhancing cell proliferation, migration and invasion.
Li Y, Sun S, Zhang H, Jing Y, Ji X, Wan Q, Liu Y
Respiratory research 2024 Jul 5;25(1):267
Respiratory research 2024 Jul 5;25(1):267
The Use of Polysaccharide AOP30 from the Rhizome of Alpinia officinarum Hance to Alleviate Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction and Inflammation via the TLR4/NfκB Signaling Pathway in Caco-2 Cell Monolayers.
Jia X, Huang Y, Liu G, Li Z, Tan Q, Zhong S
Nutrients 2024 Jul 5;16(13)
Nutrients 2024 Jul 5;16(13)
Tangeretin Enhances Muscle Endurance and Aerobic Metabolism in Mice via Targeting AdipoR1 to Increase Oxidative Myofibers.
Li J, Li J, Ullah A, Shi X, Zhang X, Cui Z, Lyu Q, Kou G
Journal of agricultural and food chemistry 2024 Jul 31;72(30):16687-16699
Journal of agricultural and food chemistry 2024 Jul 31;72(30):16687-16699
Eg5 UFMylation promotes spindle organization during mitosis.
Li G, Huang Y, Han W, Wei L, Huang H, Zhu Y, Xiao Q, Wang Z, Huang W, Duan R
Cell death & disease 2024 Jul 31;15(7):544
Cell death & disease 2024 Jul 31;15(7):544
Systematic analysis of TREM2 and its carcinogenesis in pancreatic cancer.
Zheng W, Yu W, Hua R, He J, Wu N, Tian S, Huang W, Qin L
Translational cancer research 2024 Jul 31;13(7):3200-3216
Translational cancer research 2024 Jul 31;13(7):3200-3216
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Li H, Wang P, Hu M, Xu S, Li X, Xu D, Feng K, Zhou Q, Chang M, Yao S
International immunopharmacology 2024 Jul 30;136:112368
International immunopharmacology 2024 Jul 30;136:112368
Identification and experimental verification of immune-related hub genes in intervertebral disc degeneration.
Huang Z, Cai X, Shen X, Chen Z, Zhang Q, Liu Y, Lu B, Xu B, Li Y
Heliyon 2024 Jul 30;10(14):e34530
Heliyon 2024 Jul 30;10(14):e34530
Upregulation of LncRNA UCA1 promotes cardiomyocyte proliferation by inhibiting the miR-128/SUZ12/P27 pathway.
Huang K, Huang D, Li Q, Zhong J, Zhou Y, Zhong Z, Tang S, Zhang W, Chen Z, Lu S
Heliyon 2024 Jul 30;10(14):e34181
Heliyon 2024 Jul 30;10(14):e34181
Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus.
Badu P, Baniulyte G, Sammons MA, Pager CT
bioRxiv : the preprint server for biology 2024 Jul 3;
bioRxiv : the preprint server for biology 2024 Jul 3;
Baicalin attenuates PD-1/PD-L1 axis-induced immunosuppression in piglets challenged with Glaesserella parasuis by inhibiting the PI3K/Akt/mTOR and RAS/MEK/ERK signalling pathways.
Fu S, Li J, You J, Liu S, Dong Q, Fu Y, Luo R, Sun Y, Tian X, Liu W, Zhang J, Ding Y, Zhang Y, Wang W, Guo L, Qiu Y
Veterinary research 2024 Jul 29;55(1):95
Veterinary research 2024 Jul 29;55(1):95
CHIP-mediated ubiquitin degradation of BCAT1 regulates glioma cell proliferation and temozolomide sensitivity.
Lu Z, Wang XY, He KY, Han XH, Wang X, Zhang Z, Qu XH, Chen ZP, Han XJ, Wang T
Cell death & disease 2024 Jul 29;15(7):538
Cell death & disease 2024 Jul 29;15(7):538
N6-Methyladenosine enhances the translation of ENO1 to promote the progression of bladder cancer by inhibiting PCNA ubiquitination.
Shen C, Liu J, Xie F, Yu Y, Ma X, Hu D, Liu C, Wang Y
Cancer letters 2024 Jul 28;595:217002
Cancer letters 2024 Jul 28;595:217002
Repurposing GnRH-A as a Near-Infrared Fluorescent Probe for Diagnosis and Surgical Navigation of Breast Cancer Tumors and Metastases.
Xu H, Ye Z, Gao X, Dai Y, Luo Y, Han Z, Gu Y
Journal of medicinal chemistry 2024 Jul 25;67(14):12386-12398
Journal of medicinal chemistry 2024 Jul 25;67(14):12386-12398
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication.
Ong HW, Yang X, Smith JL, Dickmander RJ, Brown JW, Havener TM, Taft-Benz S, Howell S, Sanders MK, Capener JL, Couñago RM, Chang E, Krämer A, Moorman NJ, Heise M, Axtman AD, Drewry DH, Willson TM
Journal of medicinal chemistry 2024 Jul 25;67(14):12261-12313
Journal of medicinal chemistry 2024 Jul 25;67(14):12261-12313
Deciphering the Effects of the PYCR Family on Cell Function, Prognostic Value, Immune Infiltration in ccRCC and Pan-Cancer.
Chen H, Chen Q, Chen J, Mao Y, Duan L, Ye D, Cheng W, Chen J, Gao X, Lin R, Lin W, Zhang M, Qi Y
International journal of molecular sciences 2024 Jul 25;25(15)
International journal of molecular sciences 2024 Jul 25;25(15)
Dihydrotanshinone I targets ESR1 to induce DNA double-strand breaks and proliferation inhibition in hepatocellular carcinoma.
Nie Y, Yan J, Huang X, Jiang T, Zhang S, Zhang G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155767
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155767
Molecular mechanism of Chang Shen Hua volatile oil modulating brain cAMP-PKA-CREB pathway to improve depression-like behavior in rats.
Zhang S, Hu Y, Zhao Y, Feng Y, Wang X, Miao M, Miao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155729
Icariside II modulates pulmonary fibrosis via PI3K/Akt/β-catenin pathway inhibition of M2 macrophage program.
Deng L, Ouyang B, Tang W, Wang N, Yang F, Shi H, Zhang Z, Yu H, Chen M, Wei Y, Dong J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155687
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155687
Salvianolic acid B protects against UVB-induced skin aging via activation of NRF2.
Sun JM, Liu YX, Liu YD, Ho CK, Tsai YT, Wen DS, Huang L, Zheng DN, Gao Y, Zhang YF, Yu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155676
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155676
Effect of luteolin on glioblastoma's immune microenvironment and tumor growth suppression.
Zong S, Li X, Zhang G, Hu J, Li H, Guo Z, Zhao X, Chen J, Wang Y, Jing Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155611
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155611
SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration.
Liu X, Liu K, Wang Y, Meng X, Wang Q, Tao S, Xu Q, Shen X, Gao X, Hong S, Jin H, Wang JQ, Wang D, Lu L, Meng Z, Wang L
Cell reports 2024 Jul 23;43(7):114458
Cell reports 2024 Jul 23;43(7):114458
Stress-induced TDP-43 nuclear condensation causes splicing loss of function and STMN2 depletion.
Huang WP, Ellis BCS, Hodgson RE, Sanchez Avila A, Kumar V, Rayment J, Moll T, Shelkovnikova TA
Cell reports 2024 Jul 23;43(7):114421
Cell reports 2024 Jul 23;43(7):114421
Enhanced therapeutic impact of Shikonin-encapsulated exosomes in the inhibition of colorectal cancer progression.
Lu Y, Zhou H, Han C, Gong Y, Li Y, Xia Y, Liang B, Yang H, Wang Z
Nanotechnology 2024 Jul 23;35(41)
Nanotechnology 2024 Jul 23;35(41)
Empagliflozin protects against heart failure with preserved ejection fraction partly by inhibiting the senescence-associated STAT1-STING axis.
Shi Y, Zhao L, Wang J, Liu X, Bai Y, Cong H, Li X
Cardiovascular diabetology 2024 Jul 23;23(1):269
Cardiovascular diabetology 2024 Jul 23;23(1):269
Effect of Bioactive Black Phosphorus Nanomaterials on Cancer-Associated Fibroblast Heterogeneity in Pancreatic Cancer.
Qu J, Yan Z, Lei D, Zhong T, Fang C, Wen Z, Liu J, Lai Z, Yu XF, Zheng B, Geng S
ACS nano 2024 Jul 23;18(29):19354-19368
ACS nano 2024 Jul 23;18(29):19354-19368
Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma.
Li XB, Li JL, Wang C, Zhang Y, Li J
European journal of histochemistry : EJH 2024 Jul 22;68(3)
European journal of histochemistry : EJH 2024 Jul 22;68(3)
Alpha 1,3 N-Acetylgalactosaminyl Transferase (GTA) Impairs Invasion Potential of Trophoblast Cells in Preeclampsia.
Li Y, Wu H, Pei X, Liu S, Yan Q
International journal of molecular sciences 2024 Jul 2;25(13)
International journal of molecular sciences 2024 Jul 2;25(13)
Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway.
Yang Q, Chen Q, Li S, Luo J
Diabetology & metabolic syndrome 2024 Jul 2;16(1):146
Diabetology & metabolic syndrome 2024 Jul 2;16(1):146
Acceleration of bone repairation by BMSCs overexpressing NGF combined with NSA and allograft bone scaffolds.
Ji Y, Mao Y, Lin H, Wang Y, Zhao P, Guo Y, Gu L, Fu C, Chen X, Lv Z, Wang N, Li Q, Bei C
Stem cell research & therapy 2024 Jul 2;15(1):194
Stem cell research & therapy 2024 Jul 2;15(1):194
ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.
Wang L, He L, Yi W, Wang M, Xu F, Liu H, Nie J, Pan YH, Dang S, Zhang W
iScience 2024 Jul 19;27(7):110273
iScience 2024 Jul 19;27(7):110273
PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function.
Shao Y, Zhang H, Guan H, Wu C, Qi W, Yang L, Yin J, Zhang H, Liu L, Lu Y, Zhao Y, Zhang S, Zeng C, Wang G, Bai X, Cai D
Bone research 2024 Jul 17;12(1):41
Bone research 2024 Jul 17;12(1):41
Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling.
Chen M, Shen C, Chen Y, Chen Z, Zhou K, Chen Y, Li W, Zeng C, Qing Y, Wu D, Xu C, Tang T, Che Y, Qin X, Xu Z, Wang K, Leung K, Sau L, Deng X, Hu J, Wu Y, Chen J
Cell reports. Medicine 2024 Jul 16;5(7):101645
Cell reports. Medicine 2024 Jul 16;5(7):101645
H3K27ac acts as a molecular switch for doxorubicin-induced activation of cardiotoxic genes.
Hong Y, Li X, Li J, He Q, Huang M, Tang Y, Chen X, Chen J, Tang KJ, Wei C
Clinical epigenetics 2024 Jul 16;16(1):91
Clinical epigenetics 2024 Jul 16;16(1):91
Interior decorative volatile organic compounds exposure induces sleep disorders through aberrant branched chain amino acid transaminase 2 mediated glutamatergic signaling resulting from a neuroinflammatory cascade.
Zheng J, Wu M, Pang Y, Liu Q, Liu Y, Jin X, Tang J, Bao L, Niu Y, Zheng Y, Zhang R
The Science of the total environment 2024 Jul 15;934:173254
The Science of the total environment 2024 Jul 15;934:173254
Paraquat disrupts KIF5A-mediated axonal mitochondrial transport in midbrain neurons and its antagonism by melatonin.
Hong H, Li J, Tong T, Yang T, Wang H, Xu Y, Lin X, Lin J, Liu S, Luo K, Yu Z, Yuan W, Pi H, Zhou Z
The Science of the total environment 2024 Jul 15;934:173119
The Science of the total environment 2024 Jul 15;934:173119
Dysregulation of hepatic one-carbon metabolism in classical homocystinuria: Implications of redox-sensitive DHFR repression and tetrahydrofolate depletion for pathogenesis and treatment.
Maclean KN, Jiang H, Neill PD, Chanin RR, Hurt KJ, Orlicky DJ, Bottiglieri T, Roede JR, Stabler SP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23795
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23795
Bmal1 regulates female reproduction in mice via the hypothalamic-pituitary-ovarian axis.
Zhang A, Li S, Huang L, Jiang Y, Chen Y, Zhu S, Xiong F, Luo Z, Ou M, Ying J, Wang S, Mu D, Qu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23744
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23744
Aqueous extract of Epimedium sagittatum (Sieb. et Zucc.) Maxim. induces liver injury in mice via pyroptosis.
Song L, Wang D, Zhai Y, Zhang X, Zhang Y, Yu Y, Sun L, Zhou K
Journal of ethnopharmacology 2024 Jul 15;329:118164
Journal of ethnopharmacology 2024 Jul 15;329:118164
Paeonia lactiflora Pall. ameliorates acetaminophen-induced oxidative stress and apoptosis via inhibiting the PKC-ERK pathway.
Li Y, Deng X, Hu Q, Chen Y, Zhang W, Qin X, Wei F, Lu X, Ma X, Zeng J, Efferth T
Journal of ethnopharmacology 2024 Jul 15;329:118107
Journal of ethnopharmacology 2024 Jul 15;329:118107
Perfluorooctane sulfonate induces ferroptosis-dependent non-alcoholic steatohepatitis via autophagy-MCU-caused mitochondrial calcium overload and MCU-ACSL4 interaction.
Ren S, Wang J, Dong Z, Li J, Ma Y, Yang Y, Zhou T, Qiu T, Jiang L, Li Q, Sun X, Yao X
Ecotoxicology and environmental safety 2024 Jul 15;280:116553
Ecotoxicology and environmental safety 2024 Jul 15;280:116553
The common pathogenesis of nodular goiter in both sexes: An exploration into gene expression and signaling pathways.
Gao X, Gao J, Sun Y, Zhao J, Geng L, Wang C, Qiao M, Wang J
Heliyon 2024 Jul 15;10(13):e33411
Heliyon 2024 Jul 15;10(13):e33411
Integrating network pharmacology and experimental models to investigate the efficacy and mechanism of Tiansha mixture on xerosis.
Deng Y, Fang X, Xu L, Wang H, Gan Q, Wang Q, Jiang M
Archives of dermatological research 2024 Jul 13;316(7):468
Archives of dermatological research 2024 Jul 13;316(7):468
LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway.
Luo B, Zhuang L, Huang J, Shi L, Zhang L, Zhu M, Lu Y, Zhu Q, Sun D, Wang H, Fang H
Journal of cancer research and clinical oncology 2024 Jul 13;150(7):351
Journal of cancer research and clinical oncology 2024 Jul 13;150(7):351
Nuclear alpha-synuclein accelerates cell senescence and neurodegeneration.
Du T, Li G, Zong Q, Luo H, Pan Y, Ma K
Immunity & ageing : I & A 2024 Jul 12;21(1):47
Immunity & ageing : I & A 2024 Jul 12;21(1):47
Therapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis.
Wang Y, Han J, Yang G, Zheng S, Zhou G, Liu X, Cao X, Li G, Zhang B, Xie Z, Li L, Zhang M, Li X, Chen M, Zhang S
Nature communications 2024 Jul 12;15(1):5874
Nature communications 2024 Jul 12;15(1):5874
RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway.
Huang F, Dai Z, Yu J, Wang K, Chen C, Chen D, Zhang J, Zhao J, Li M, Zhang W, Li X, Qi Y, Wang Y
eLife 2024 Jul 12;13
eLife 2024 Jul 12;13
Genome-scale exon perturbation screens uncover exons critical for cell fitness.
Xiao MS, Damodaran AP, Kumari B, Dickson E, Xing K, On TA, Parab N, King HE, Perez AR, Guiblet WM, Duncan G, Che A, Chari R, Andresson T, Vidigal JA, Weatheritt RJ, Aregger M, Gonatopoulos-Pournatzis T
Molecular cell 2024 Jul 11;84(13):2553-2572.e19
Molecular cell 2024 Jul 11;84(13):2553-2572.e19
Butyrate induces higher host transcriptional changes to inhibit porcine epidemic diarrhea virus strain CV777 infection in porcine intestine epithelial cells.
Zhong Z, Zhang Y, Zhao X, Zhou C, Zhu S, Wu J
Virology journal 2024 Jul 11;21(1):157
Virology journal 2024 Jul 11;21(1):157
Cerebral Endothelial CXCR2 Promotes Neutrophil Transmigration into Central Nervous System in LPS-Induced Septic Encephalopathy.
Wu F, Han Y, Xiong Q, Tang H, Shi J, Yang Q, Li X, Jia H, Qian J, Dong Y, Li T, Gao Y, Qian Z, Wang H, Wang T
Biomedicines 2024 Jul 11;12(7)
Biomedicines 2024 Jul 11;12(7)
The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.
Wang X, Wang S, Xu X, Jiang Y, Ren L, Zhang H, Li Z, Liu X, Hu X, Ren Y
Parasites & vectors 2024 Jul 10;17(1):299
Parasites & vectors 2024 Jul 10;17(1):299
Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC.
Li H, Fei M, Zhang Y, Xu Q, Feng R, Cao J, Qu Y, Xiao H
Gene 2024 Jul 1;914:148403
Gene 2024 Jul 1;914:148403
Circular RNA CircVmn2r1 Acts as a miR-223-3p Sponge to Promote Kidney Aging by Regulating NLRP3 Expression in Mice.
Gao F, Wei L, Li J, Zeng L, Wang M, Lan P, Liang S, Huang X, Chen L, Jiang H
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Jul 1;79(7)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Jul 1;79(7)
PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3.
Sun JT, Wang ZM, Zhou LH, Yang TT, Zhao D, Bao YL, Wang SB, Gu LF, Chen JW, Shan TK, Wei TW, Wang H, Wang QM, Kong XQ, Xie LP, Gu AH, Zhao Y, Chen F, Ji Y, Cui YQ, Wang LS
Communications biology 2024 Jul 1;7(1):795
Communications biology 2024 Jul 1;7(1):795
Se-methylselenocysteine inhibits the progression of non-small cell lung cancer via ROS-mediated NF-κB signaling pathway.
Ge L, Liu P, Tian L, Li Y, Chen L
Experimental cell research 2024 Jul 1;440(1):114101
Experimental cell research 2024 Jul 1;440(1):114101
O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis.
Yu F, Zhang Z, Leng Y, Chen AF
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jan;73(1):5-17
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jan;73(1):5-17
TBX5 pathogenic variant in a patient with congenital heart defect and tracheal stenosis.
Yamoto K, Kato F, Yamoto M, Fukumoto K, Shimizu K, Saitsu H, Ogata T
Congenital anomalies 2024 Jan;64(1):23-27
Congenital anomalies 2024 Jan;64(1):23-27
FGF-18 Protects the Injured Spinal cord in mice by Suppressing Pyroptosis and Promoting Autophagy via the AKT-mTOR-TRPML1 axis.
Li F, Cai T, Yu L, Yu G, Zhang H, Geng Y, Kuang J, Wang Y, Cai Y, Xiao J, Wang X, Ding J, Xu H, Ni W, Zhou K
Molecular neurobiology 2024 Jan;61(1):55-73
Molecular neurobiology 2024 Jan;61(1):55-73
Hantaan virus inhibits type I interferon response by targeting RLR signaling pathways through TRIM25.
Zhao Y, Che L, Pan M, Huang Y, Fang S, Wang M, Sui L, Wang ZD, Du F, Hou Z, Liu Q
Virology 2024 Jan;589:109942
Virology 2024 Jan;589:109942
The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study.
Yu S, Guo J, Yang D, Yan X, Zhang Z, Wei P, Qiu L
International endodontic journal 2024 Jan;57(1):50-63
International endodontic journal 2024 Jan;57(1):50-63
Fish oil omega-3 Fatty Acids Alleviate Postoperative delirium-like Behavior in aged mice by Attenuating Neuroinflammation and Oxidative Stress.
Zhu M, Li M, Yang S, Li J, Gong C, Yu Q, Chen C, Zhang Y, Lin J, Tu F
Neurochemical research 2024 Jan;49(1):157-169
Neurochemical research 2024 Jan;49(1):157-169
NMNATs expression inhibition mediated NAD(+) deficiency plays a critical role in doxorubicin-induced hepatotoxicity in mice.
Cheng F, Zhang Y, Xiong H, Zhao M, Wang Q, Zhu Y, Li Y, Tang R, Li J
Toxicology and applied pharmacology 2024 Jan;482:116799
Toxicology and applied pharmacology 2024 Jan;482:116799
Icariin rescues developmental BPA exposure induced spatial memory deficits in rats.
Li D, Ai S, Huang C, Liu ZH, Wang HL
Toxicology and applied pharmacology 2024 Jan;482:116776
Toxicology and applied pharmacology 2024 Jan;482:116776
The lack of homology domain and leucine rich repeat protein phosphatase 2 ameliorates visual impairment in rats with diabetic retinopathy through regulation of the AKT-GSK-3β-Nrf2 signal cascade.
Chen L, Qi E, Liu X, Cui L, Fan X, Wei T, Hu Y
Toxicology and applied pharmacology 2024 Jan;482:116766
Toxicology and applied pharmacology 2024 Jan;482:116766
Long Non-Coding RNA H19 Leads to Upregulation of γ-Globin Gene Expression during Erythroid Differentiation.
Xie D, Han Y, Zhang W, Wu J, An B, Huang S, Sun F
Hemoglobin 2024 Jan;48(1):4-14
Hemoglobin 2024 Jan;48(1):4-14
Autocrine motility factor receptor promotes the malignancy of glioblastoma by regulating cell migration and invasion.
Zhang Y, Wang X, Chen G, Lu Y, Chen Q
Neurological research 2024 Jan;46(1):89-97
Neurological research 2024 Jan;46(1):89-97
Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis.
Liu H, Deng R, Zhu CW, Han HK, Zong GF, Ren L, Cheng P, Wei ZH, Zhao Y, Yu SY, Lu Y
Acta pharmacologica Sinica 2024 Jan;45(1):193-208
Acta pharmacologica Sinica 2024 Jan;45(1):193-208
Amplifying T cell-mediated antitumor immune responses in nonsmall cell lung cancer through photodynamic therapy and anti-PD1.
Gong B, Wang L, Zhang H, Wang Q, Li W
Cell biochemistry and function 2024 Jan;42(1):e3925
Cell biochemistry and function 2024 Jan;42(1):e3925
NADase CD38 is a key determinant of ovarian aging.
Yang Q, Chen W, Cong L, Wang M, Li H, Wang H, Luo X, Zhu J, Zeng X, Zhu Z, Xu Y, Lei M, Zhao Y, Wei C, Sun Y
Nature aging 2024 Jan;4(1):110-128
Nature aging 2024 Jan;4(1):110-128
Role of PLC/IP(3) /IP(3) R axis in excess molybdenum exposure induced apoptosis in duck renal tubular epithelial cells.
Guo H, Zhang C, Pu W, Chu X, Huang G, Cui T, Huang B, Liu H, Dai X
Environmental toxicology 2024 Jan;39(1):172-183
Environmental toxicology 2024 Jan;39(1):172-183
CircNEK6 promotes the progression of pancreatic ductal adenocarcinoma through targeting miR-503/CCND1 axis.
Shao Z, Chen X, Qiu H, Xu M, Wen X, Chen Z, Liu Z, Ding X, Zhang L
Translational oncology 2024 Jan;39:101810
Translational oncology 2024 Jan;39:101810
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Huo J, Dong W, Xu J, Ma L, You C
Experimental neurology 2024 Jan;371:114577
Experimental neurology 2024 Jan;371:114577
Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.
Zhou M, Wu Y, Sun M, Qin Y, Zhao J, Qiu Z, Li C, Zhang Y, Xiong Y, Shen Y, Zou Z, Tu J, Shen W, Sun C
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Zhang J, Su L, Liu Z, Tang J, Zhang L, Li Z, Zhou D, Sun Z, Xi K, Lu P, Deng G
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Multi-omics Analysis Identifies Hypoxia Subtypes and S100A2 as an Immunosuppressive Factor in Cervical Cancer.
Yang J, Wan S, Zhao M, Cai H, Gao Y, Wang H
Reproductive sciences (Thousand Oaks, Calif.) 2024 Jan;31(1):107-121
Reproductive sciences (Thousand Oaks, Calif.) 2024 Jan;31(1):107-121
FOXA2 activates HIF2α expression to promote tumor progression and is regulated by the E3 ubiquitin ligase VHL in renal cell carcinoma.
Yang D, Li Q, Lu P, Wu D, Li W, Meng X, Xing M, Shangguan W, Chen B, Yang J, Zhang Z, Wang Z, Huang DCS, Zhao Q
The Journal of biological chemistry 2024 Jan;300(1):105535
The Journal of biological chemistry 2024 Jan;300(1):105535
Exosomal miR-23a-3p derived from human umbilical cord mesenchymal stem cells promotes remyelination in central nervous system demyelinating diseases by targeting Tbr1/Wnt pathway.
Qin D, Wang C, Li D, Guo S
The Journal of biological chemistry 2024 Jan;300(1):105487
The Journal of biological chemistry 2024 Jan;300(1):105487
MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
An Q, Xia J, Pu F, Shi S
Molecular medicine reports 2024 Jan;29(1)
Molecular medicine reports 2024 Jan;29(1)
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Shi X, Yang J, Wang M, Xia L, Zhang L, Qiao S
Oncology letters 2024 Jan;27(1):2
Oncology letters 2024 Jan;27(1):2
Integrative analysis of cuproptosis-associated genes for predicting immunotherapy response in single-cell and multi-cohort studies.
Li H, Wang Y, Li G, Xiong J, Qin L, Wen Q, Yue C
The journal of gene medicine 2024 Jan;26(1):e3600
The journal of gene medicine 2024 Jan;26(1):e3600
Engineering of targeting antioxidant polypeptide nanopolyplexes for the treatment of acute lung injury.
Li YX, Bao YT, Hu JB
International journal of biological macromolecules 2024 Jan;254(Pt 3):127872
International journal of biological macromolecules 2024 Jan;254(Pt 3):127872
Arginine-methylated c-Myc affects mitochondrial mitophagy in mouse acute kidney injury via Slc25a24.
Liu Y, Liu N, He P, Cao S, Li H, Liu D
Journal of cellular physiology 2024 Jan;239(1):193-211
Journal of cellular physiology 2024 Jan;239(1):193-211
Carrier-free nanodrug targeting glucose metabolism for enhanced rheumatoid arthritis treatment.
Chen T, Lin X, Li D, Pan L, Qin X, Ye W, Luo Z, Wang Q
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113668
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113668
Self-assembled and dynamic bond crosslinked herb-polysaccharide hydrogel with anti-inflammation and pro-angiogenesis effects for burn wound healing.
Wu H, Wang T, Liang Y, Chen L, Li Z
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113639
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113639
YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes.
Chen H, Shang Y, Li X, Wang R
Cell cycle (Georgetown, Tex.) 2024 Jan;23(1):83-91
Cell cycle (Georgetown, Tex.) 2024 Jan;23(1):83-91
LAFEM: A Scoring Model to Evaluate Functional Landscape of Lysine Acetylome.
Liang JZ, Li DH, Xiao YC, Shi FJ, Zhong T, Liao QY, Wang Y, He QY
Molecular & cellular proteomics : MCP 2024 Jan;23(1):100700
Molecular & cellular proteomics : MCP 2024 Jan;23(1):100700
Photobiomodulation Facilitates Rat Cutaneous Wound Healing by Promoting Epidermal Stem Cells and Hair Follicle Stem Cells Proliferation.
Wang T, Song Y, Yang L, Liu W, He Z, Shi Y, Song B, Yu Z
Tissue engineering and regenerative medicine 2024 Jan;21(1):65-79
Tissue engineering and regenerative medicine 2024 Jan;21(1):65-79
CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.
Liu X, Fang Y, Qian C, Chen J, Luo W, Zuo W, Lin J, Xie L, Liang G, Huang L, Wang Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166893
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166893
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Wang R, Feng W, Wang Y, Jiang Y, Lin Y, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Integrating multi-level interactive network and in vivo/vitro studies to explore the protective mechanism of Ampelopsis grossedentata in hyperuricemia.
Zhou QX, Zhou Q, Zhang P, Xie YQ, Yang ZY, Tan WH, Khan A, Duan WG, Zhou ZH, Liu L
Fitoterapia 2024 Jan;172:105718
Fitoterapia 2024 Jan;172:105718
Shen Qi Wan ameliorates nephritis in chronic kidney disease via AQP1 and DEFB1 regulation.
Liu Y, Hong X, Liu L, Li X, Huang S, Luo Q, Huang Q, Qiu J, Qiu P, Li C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116027
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116027
Inhibition of cGAS-STING pathway by stress granules after activation of M2 macrophages by human mesenchymal stem cells against drug induced liver injury.
Wang Y, She S, Li W, Zhu J, Li X, Yang F, Dai K
Molecular immunology 2024 Jan;165:42-54
Molecular immunology 2024 Jan;165:42-54
Discovery of Taurocholic Acid Sodium Hydrate as a Novel Repurposing Drug for Intervertebral Disc Degeneration by Targeting MAPK3.
Li P, Chen Z, Meng K, Chen Y, Xu J, Xiang X, Wu X, Huang Z, Lai R, Li P, Lai Z, Ao X, Liu Z, Yang K, Bai X, Zhang Z
Orthopaedic surgery 2024 Jan;16(1):183-195
Orthopaedic surgery 2024 Jan;16(1):183-195
High glucose levels delay the senescence of stem cells from human exfoliated deciduous teeth by suppressing autophagy.
Lu J, Zhang L, Zhu N, Wang D, Xie F, Qin M, Wang Y
Archives of oral biology 2024 Jan;157:105851
Archives of oral biology 2024 Jan;157:105851
IL-22-Induced Ubiquitin-Specific Protease 15 Promotes Proliferation and Inflammation of Keratinocytes through Stabilization of Squamous Cell Carcinoma Antigen 2.
Chen F, Wu S, Zhan J, Jin Y, Xuan X, Cao J, Wu T, Liang Y, Zhao X, Li Z, Wang Y, Chen L, Li Y, El Ghalbzouri A, Huang C
The Journal of investigative dermatology 2024 Jan;144(1):63-72.e4
The Journal of investigative dermatology 2024 Jan;144(1):63-72.e4
Mast Cells Initiate Type 2 Inflammation through Tryptase Released by MRGPRX2/MRGPRB2 Activation in Atopic Dermatitis.
Jia T, Che D, Zheng Y, Zhang H, Li Y, Zhou T, Peng B, Du X, Zhu L, An J, Geng S
The Journal of investigative dermatology 2024 Jan;144(1):53-62.e2
The Journal of investigative dermatology 2024 Jan;144(1):53-62.e2
Green synthesis and anti-tumor efficacy via inducing pyroptosis of novel 1H-benzo[e]indole-2(3H)-one spirocyclic derivatives.
Wu J, Liu X, Zhang J, Yao J, Cui X, Tang Y, Xi Z, Han M, Tian H, Chen Y, Fan Q, Li W, Kong D
Bioorganic chemistry 2024 Jan;142:106930
Bioorganic chemistry 2024 Jan;142:106930
LncRNA BCRT1 depletion suppresses cervical cancer cell growth via sponging miR-432-5p/CCR7 axis.
Wang X, Li H, Li N, Yang H, Bai X
3 Biotech 2024 Jan;14(1):17
3 Biotech 2024 Jan;14(1):17
Grape seed-derived procyanidin inhibits glyphosate-induced hepatocyte ferroptosis via enhancing crosstalk between Nrf2 and FGF12.
Liu J, Li K, Li S, Yang G, Lin Z, Miao Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155278
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155278
Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis.
Meng C, Zhou L, Huang L, Gu Q, Du X, Wang C, Liu F, Xia C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155271
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155271
CircPHKB decreases the sensitivity of liver cancer cells to sorafenib via miR-1234-3p/CYP2W1 axis.
Chen L, Xiao H, Wu Y, Yan D, Shan M, Sun L, Yan X, Liu D, Li T, Zhang Y, Xiang L, Chen A, Li S, Xiang W, Ni Z, He F, Yang M, Lian J
Genomics 2024 Jan;116(1):110764
Genomics 2024 Jan;116(1):110764
CircBRD7 attenuates tumor growth and metastasis in nasopharyngeal carcinoma via epigenetic activation of its host gene.
Wei J, Li M, Chen S, Xue C, Zheng L, Duan Y, Deng H, Fan S, Xiong W, Zhou M
Cancer science 2024 Jan;115(1):139-154
Cancer science 2024 Jan;115(1):139-154
Hydro-Sensitive, In Situ Ultrafast Physical Self-Gelatinizing, and Red Blood Cells Strengthened Hemostatic Adhesive Powder with Antibiosis and Immunoregulation for Wound Repair.
Shang L, Yan Y, Li Z, Liu H, Ge S, Ma B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2306528
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2306528
Uncovering the mechanism of Naoxintong capsule against hypertension based on network analysis and in vitro experiments.
Chen X, Hu L, Wang R, Luo M, Wei C, Li P, Yu H
Chemical biology & drug design 2024 Jan;103(1):e14440
Chemical biology & drug design 2024 Jan;103(1):e14440
Study of hispidulin in the treatment of uric acid nephropathy based on NF-κB signaling pathway.
Li X, Gu Y, Ren L, Cai Q, Qiu Y, He J, Qu W, Ji W
Chemical biology & drug design 2024 Jan;103(1):e14367
Chemical biology & drug design 2024 Jan;103(1):e14367
Necroptosis involved in sevoflurane-induced cognitive dysfunction in aged mice by activating NMDA receptors increasing intracellular calcium.
Liu X, Yu J, Tan X, Zhang Q, Niu J, Hou Z, Wang Q
Neurotoxicology 2024 Jan;100:35-46
Neurotoxicology 2024 Jan;100:35-46
Sestrin 2 protects human lens epithelial cells from oxidative stress and apoptosis induced by hydrogen peroxide by regulating the mTOR/Nrf2 pathway.
Tian X, Wei J
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241234741
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241234741
Chinese Herbal Compound Xiaoliu Pingyi Recipe Inhibits the Growth of Lung Adenocarcinoma by Regulating the Tumor Vascular Microenvironment.
Yang FR, Li HL, Hu XW, Fu R, Li XR, Li HJ
Integrative cancer therapies 2024 Jan-Dec;23:15347354241273962
Integrative cancer therapies 2024 Jan-Dec;23:15347354241273962
Systematic Characterization of DNA Methyltransferases Family in Tumor Progression and Antitumor Immunity.
Huang F, Wu X, Du Q, Lin J, Ma W, Liu J
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241260658
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241260658
A Comprehensive Prognostic Model for Colon Adenocarcinoma Depending on Nuclear-Mitochondrial-Related Genes.
Lv L, Huang Y, Li Q, Wu Y, Zheng L
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241258570
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241258570
Intestinal deguelin drives resistance to acetaminophen-induced hepatotoxicity in female mice.
Gong S, Zeng Y, Wang Z, Li Y, Wu R, Li L, Hu H, Qin P, Yu Z, Huang X, Guo P, Yang H, He Y, Zhao Z, Xiao W, Zhao X, Gao L, Cai S, Zeng Z
Gut microbes 2024 Jan-Dec;16(1):2404138
Gut microbes 2024 Jan-Dec;16(1):2404138
Visualization of the Ferroptosis in Atherosclerotic Plaques with Nanoprobe Engineered by Macrophage Cell Membranes.
Gu Y, Cui M, Wang W, Zhang J, Wang H, Zheng C, Lei L, Ji M, Chen W, Xu Y, Wang P
Analytical chemistry 2024 Jan 9;96(1):281-291
Analytical chemistry 2024 Jan 9;96(1):281-291
ZNFX1 promotes AMPK-mediated autophagy against Mycobacterium tuberculosis by stabilizing Prkaa2 mRNA.
Liu H, Han Z, Chen L, Zhang J, Zhang Z, Chen Y, Liu F, Wang K, Liu J, Sai N, Zhou X, Zhou C, Hu S, Wen Q, Ma L
JCI insight 2024 Jan 9;9(1)
JCI insight 2024 Jan 9;9(1)
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Zhao WM, Li XL, Zhu Y, Shi R, Wang ZJ, Xiao JP, Wang DG
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
Danggui-Shaoyao-San (DSS) ameliorates the progression of osteoarthritis via suppressing the NF-κB signaling pathway: an in vitro and in vivo study combined with bioinformatics analysis.
Chen S, Kang P, Zhao Z, Zhang H, Li J, Xu K, Gong D, Jiao F, Wang H, Zhang M
Aging 2024 Jan 8;16(1):648-664
Aging 2024 Jan 8;16(1):648-664
Serine/threonine kinase 36 induced epithelial-mesenchymal transition promotes docetaxel resistance in prostate cancer.
He T, Li NX, Pan ZJ, Zou ZH, Chen JC, Yu SZ, Lv F, Xie QC, Zou J
Scientific reports 2024 Jan 6;14(1):729
Scientific reports 2024 Jan 6;14(1):729
EPYC functions as a novel prognostic biomarker for pancreatic cancer.
Yang Z, Li H, Hao J, Mei H, Qiu M, Wang H, Gao M
Scientific reports 2024 Jan 6;14(1):719
Scientific reports 2024 Jan 6;14(1):719
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton.
Cai J, Jiang Y, Chen P, Liang J, Zhang Y, Yuan R, Fan H, Zhong Y, Cai J, Cheng S, Zhang Y
Aging 2024 Jan 5;16(1):431-444
Aging 2024 Jan 5;16(1):431-444
ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis.
Ma X, Li M, Liu Y, Zhang X, Yang X, Wang Y, Li Y, Wang J, Liu X, Yan Z, Yu X, Wu C
Journal of molecular cell biology 2024 Jan 5;15(7)
Journal of molecular cell biology 2024 Jan 5;15(7)
Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1.
Huang Y, Peng Q, Tian X, Chen C, Zhu X, Huang C, Huo Z, Liu Y, Yang C, Liu C, Zhang P
Nature communications 2024 Jan 5;15(1):296
Nature communications 2024 Jan 5;15(1):296
miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy.
Gao X, Gao LF, Zhang ZY, Jia S, Meng CY
International immunopharmacology 2024 Jan 5;126:111331
International immunopharmacology 2024 Jan 5;126:111331
Phlorizin, a novel caloric restriction mimetic, stimulates hypoxia and protects cardiomyocytes through activating autophagy via modulating the Hif-1α/Bnip3 axis in sepsis-induced myocardial dysfunction.
Yu YW, Chen X, Yan JY, Hu J, Huang KY, Ji KT, Cai HL
International immunopharmacology 2024 Jan 5;126:111241
International immunopharmacology 2024 Jan 5;126:111241
Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress.
Liu C, Xu Y, Yang G, Tao Y, Chang J, Wang S, Cheung TH, Chen J, Zeng YA
Cell stem cell 2024 Jan 4;31(1):89-105.e6
Cell stem cell 2024 Jan 4;31(1):89-105.e6
WNTA5-mediated miR-374a-5p regulates vascular smooth muscle cell phenotype transformation and M1 macrophage polarization impacting intracranial aneurysm progression.
Li Z, Huang J, Yang L, Li X, Li W
Scientific reports 2024 Jan 4;14(1):559
Scientific reports 2024 Jan 4;14(1):559
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Zhu Q, Cao Y, Yuan J, Hu Y
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Synbiotic Combination between Lactobacillus paracasei VL8 and Mannan-Oligosaccharide Repairs the Intestinal Barrier in the Dextran Sulfate Sodium-Induced Colitis Model by Regulating the Intestinal Stem Cell Niche.
Zhang T, Cheng T, Geng S, Mao K, Li X, Gao J, Han J, Sang Y
Journal of agricultural and food chemistry 2024 Jan 31;72(4):2214-2228
Journal of agricultural and food chemistry 2024 Jan 31;72(4):2214-2228
TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance.
Sun G, Gong S, Lan S, He Y, Sun Y, Zhang Z
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jan 31;70(1):99-109
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jan 31;70(1):99-109
GRK5 promoted renal fibrosis via HDAC5/Smad3 signaling pathway.
Xiang H, Huang J, Song A, Liu F, Xiong J, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23422
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23422
MicroRNA miR-181d-5p regulates the MAPK signaling pathway by targeting mitogen-activated protein kinase 8 (MAPK8) to improve lupus nephritis.
Chai F, Peng H, Qin L, Liu C, Zeng Y, Wang R, Xu G, Wang R, Wei G, Huang H, Lan Y, Chen W, Wang C
Gene 2024 Jan 30;893:147961
Gene 2024 Jan 30;893:147961
Erchen decoction alleviates the progression of NAFLD by inhibiting lipid accumulation and iron overload through Caveolin-1 signaling.
Deng G, Li J, Huang M, Li Y, Shi H, Wu C, Zhao J, Qin M, Liu C, Yang M, Wang Y, Zhang Y, Liao Y, Zhou C, Yang J, Xu Y, Liu B, Gao L
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117320
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117320
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Shuangshuang H, Mengmeng S, Lan Z, Fang Z, Yu L
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Jin H, Liu C, Liu X, Wang H, Zhang Y, Liu Y, Li J, Yu Z, Liu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Modified Shoutai Pill inhibited ferroptosis to alleviate recurrent pregnancy loss.
Lai Y, Zhang Y, Zhang H, Chen Z, Zeng L, Deng G, Luo S, Gao J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117028
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117028
Norepinephrine protects against cochlear outer hair cell damage and noise-induced hearing loss via α(2A)-adrenergic receptor.
Tian C, Yang Y, Wang R, Li Y, Sun F, Chen J, Zha D
BMC neuroscience 2024 Jan 30;25(1):5
BMC neuroscience 2024 Jan 30;25(1):5
A Self-Homing and Traceable Cardiac Patch Leveraging Ferumoxytol for Spatiotemporal Therapeutic Delivery.
Li M, Liu Y, Huang B, Zhou G, Pan M, Jin J, Wang F, Wang Y, Ren X, Xu B, Hu B, Gu N
ACS nano 2024 Jan 30;18(4):3073-3086
ACS nano 2024 Jan 30;18(4):3073-3086
PPIP5K2 Facilitates Proliferation and Metastasis of Non-Small Lung Cancer (NSCLC) through AKT Signaling Pathway.
Yang Q, Cao C, Wu B, Yang H, Tan T, Shang D, Xu C, Huang X
Cancers 2024 Jan 30;16(3)
Cancers 2024 Jan 30;16(3)
Identification of cuproptosis-related molecular classification and characteristic genes in ulcerative colitis.
Bai X, Zhang F, Zhou C, Yan J, Liang H, Zhu R, Gong M, Song H, Niu J, Miao Y
Heliyon 2024 Jan 30;10(2):e24875
Heliyon 2024 Jan 30;10(2):e24875
Single-cell transcriptomics enable the characterization of local extension in retinoblastoma.
Liu Y, Hu W, Xie Y, Tang J, Ma H, Li J, Nie J, Wang Y, Gao Y, Cheng C, Li C, Ma Y, Su S, Zhang Z, Bao Y, Ren Y, Wang X, Sun F, Li S, Lu R
Communications biology 2024 Jan 3;7(1):11
Communications biology 2024 Jan 3;7(1):11
Preclinical Repurposing of Sitagliptin as a Drug Candidate for Colorectal Cancer by Targeting CD24/CTNNB1/SOX4-Centered Signaling Hub.
Shih JW, Wu ATH, Mokgautsi N, Wei PL, Huang YJ
International journal of molecular sciences 2024 Jan 3;25(1)
International journal of molecular sciences 2024 Jan 3;25(1)
Attenuation of PI3K-Akt-mTOR Pathway to Reduce Cancer Stemness on Chemoresistant Lung Cancer Cells by Shikonin and Synergy with BEZ235 Inhibitor.
Huang YH, Chiu LY, Tseng JS, Hsu KH, Chen CH, Sheu GT, Yang TY
International journal of molecular sciences 2024 Jan 3;25(1)
International journal of molecular sciences 2024 Jan 3;25(1)
Period circadian regulator 2-mediated steroid hormone synthesis by regulating transcription of steroidogenic acute regulatory protein in porcine granulosa cells.
Zhang Z, Cheng J, Yang L, Li X, Li Q
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury.
Du X, Ren B, Li C, Li Q, Kan S, Wang X, Bai W, Wu C, Kassegne K, Yan H, Niu X, Yan M, Xu W, Wassmer SC, Wang J, Chen G, Wang Z
Nature communications 2024 Jan 29;15(1):881
Nature communications 2024 Jan 29;15(1):881
Network pharmacology and in vitro experimental verification unveil glycyrrhizin from glycyrrhiza glabra alleviates acute pancreatitis via modulation of MAPK and STAT3 signaling pathways.
Zhang R, Asikaer A, Chen Q, Wang F, Lan J, Liu Y, Hu L, Zhao H, Duan H
BMC complementary medicine and therapies 2024 Jan 27;24(1):58
BMC complementary medicine and therapies 2024 Jan 27;24(1):58
Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway.
Wang F, Xu W, Liu X, Zhang J
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):71-81
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):71-81
Malvidin promotes PGC-1α/Nrf2 signaling to attenuate the inflammatory response and restore mitochondrial activity in septic acute kidney injury.
Fan H, Sun Y, Zhang X, Xu Y, Ming Y, Zhang L, Zhao P
Chemico-biological interactions 2024 Jan 25;388:110850
Chemico-biological interactions 2024 Jan 25;388:110850
LncRNA Gm28382 promotes lipogenesis by interacting with miR-326-3p to regulate ChREBP signaling pathway in NAFLD.
Yang S, Zhang Y, Zhang Y, Yin L, Han X, Zhao X, Wang N, Xu L
International immunopharmacology 2024 Jan 25;127:111444
International immunopharmacology 2024 Jan 25;127:111444
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Cui L, Zou S, Liu J, Lv H, Li H, Zhang Z
International immunopharmacology 2024 Jan 25;127:111404
International immunopharmacology 2024 Jan 25;127:111404
The protective effect of Ergolide in osteoarthritis: In vitro and in vivo studies.
Meng X, Sun L, Meng X, Bi Q
International immunopharmacology 2024 Jan 25;127:111355
International immunopharmacology 2024 Jan 25;127:111355
Regulation of tumor metastasis and CD8(+) T cells infiltration by circRNF216/miR-576-5p/ZC3H12C axis in colorectal cancer.
Du W, Quan X, Wang C, Song Q, Mou J, Pei D
Cellular & molecular biology letters 2024 Jan 24;29(1):19
Cellular & molecular biology letters 2024 Jan 24;29(1):19
RUNX1 targeting AKT3 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS induced ARDS.
Xiao C, Liu J, Cheng Y, Wu Y, Li Q, Chen X, Yuan J, Dong Q, Li L, Liu Y, Shen F
Respiratory research 2024 Jan 24;25(1):54
Respiratory research 2024 Jan 24;25(1):54
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Song G, Sun Z, Chu M, Zhang Z, Chen J, Wang Z, Zhu X
BMC cancer 2024 Jan 24;24(1):122
BMC cancer 2024 Jan 24;24(1):122
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer.
Lian Z, Tian P, Ma S, Chang T, Liu R, Feng Q, Li J
Aging 2024 Jan 24;16(2):1938-1951
Aging 2024 Jan 24;16(2):1938-1951
Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasms.
Gu D, Ye M, Zhu G, Bai J, Chen J, Yan L, Yu P, Lu F, Hu C, Zhong Y, Liu P, He Q, Tang Q
Journal of translational medicine 2024 Jan 23;22(1):93
Journal of translational medicine 2024 Jan 23;22(1):93
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Jia C, Xiang Z, Zhang P, Liu L, Zhu X, Yu R, Liu Z, Wang S, Liu K, Wang Z, Vasilev K, Zhou S, Geng Z, Liu X, Zhao Y, Gao Y, Cheng L, Li Y
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Identification of BANF1 as a novel prognostic biomarker in gastric cancer and validation via in-vitro and in-vivo experiments.
Xu Y, Wang X, Yuan W, Zhang L, Chen W, Hu K
Aging 2024 Jan 22;16(2):1808-1828
Aging 2024 Jan 22;16(2):1808-1828
Targeting the NAT10/NPM1 axis abrogates PD-L1 expression and improves the response to immune checkpoint blockade therapy.
Qin G, Bai F, Hu H, Zhang J, Zhan W, Wu Z, Li J, Fu Y, Deng Y
Molecular medicine (Cambridge, Mass.) 2024 Jan 20;30(1):13
Molecular medicine (Cambridge, Mass.) 2024 Jan 20;30(1):13
Discovery from Hypericum elatoides and synthesis of hyperelanitriles as α-aminopropionitrile-containing polycyclic polyprenylated acylphloroglucinols.
Xie JY, Li P, Yan XT, Gao JM
Communications chemistry 2024 Jan 2;7(1):1
Communications chemistry 2024 Jan 2;7(1):1
Heterogeneous Expression Patterns of the Minichromosome Maintenance Complex Members in Retinoblastoma Unveil Its Clinical Significance.
Tang J, Liu Y, Zhang Z, Ren Y, Ma Y, Wang Y, Li J, Gao Y, Li C, Cheng C, Su S, Chen S, Zhang P, Lu R
Investigative ophthalmology & visual science 2024 Jan 2;65(1):31
Investigative ophthalmology & visual science 2024 Jan 2;65(1):31
CCT2 prevented β-catenin proteasomal degradation to sustain cancer stem cell traits and promote tumor progression in epithelial ovarian cancer.
Chen J, Hu Q, Zhou C, Jin D
Molecular biology reports 2024 Jan 2;51(1):54
Molecular biology reports 2024 Jan 2;51(1):54
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding.
Lin Y, Wu Y, Zhang Q, Tu X, Chen S, Pan J, Xu N, Lin M, She P, Niu G, Chen Y, Li H
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):1
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):1
Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.
Rashidi A, Billingham LK, Zolp A, Chia TY, Silvers C, Katz JL, Park CH, Delay S, Boland L, Geng Y, Markwell SM, Dmello C, Arrieta VA, Zilinger K, Jacob IM, Lopez-Rosas A, Hou D, Castro B, Steffens AM, McCortney K, Walshon JP, Flowers MS, Lin H, Wang H, Zhao J, Sonabend A, Zhang P, Ahmed AU, Brat DJ, Heiland DH, Lee-Chang C, Lesniak MS, Chandel NS, Miska J
Cell metabolism 2024 Jan 2;36(1):62-77.e8
Cell metabolism 2024 Jan 2;36(1):62-77.e8
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Zhu Y, Jian X, Chen S, An G, Jiang D, Yang Q, Zhang J, Hu J, Qiu Y, Feng X, Guo J, Chen X, Li Z, Zhou R, Hu C, He N, Shi F, Huang S, Liu H, Li X, Xie L, Zhu Y, Zhao L, Jiang Y, Li J, Wang J, Qiu L, Chen X, Jia W, He Y, Zhou W
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Cell metabolism 2024 Jan 2;36(1):159-175.e8
The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury.
Yan X, Xia Y, Li B, Ye Z, Li L, Yuan T, Song B, Yu W, Rao T, Ning J, Lin F, Mei S, Mao Z, Zhou X, Li W, Cheng F
Journal of translational medicine 2024 Jan 2;22(1):9
Journal of translational medicine 2024 Jan 2;22(1):9
Diallyl trisulfide inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via modulating gut microbiota and the PPARγ/NF-κB pathway.
Qu Z, Tian J, Sun J, Shi Y, Yu J, Zhang W, Zhuang C
Food & function 2024 Jan 2;15(1):158-171
Food & function 2024 Jan 2;15(1):158-171
Aging-Associated ALKBH5-m(6)A Modification Exacerbates Doxorubicin-Induced Cardiomyocyte Apoptosis Via AT-Rich Interaction Domain 2.
Chen R, Zhang G, Sun K, Chen AF
Journal of the American Heart Association 2024 Jan 2;13(1):e031353
Journal of the American Heart Association 2024 Jan 2;13(1):e031353
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Hui Y, Kuang L, Zhong Y, Tang Y, Xu Z, Zheng T
iScience 2024 Jan 19;27(1):108689
iScience 2024 Jan 19;27(1):108689
Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.
Cheng Z, Huang H, Li M, Chen Y
iScience 2024 Jan 19;27(1):108645
iScience 2024 Jan 19;27(1):108645
IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects.
Liu Y, Dang Y, Zhang C, Liu L, Cai W, Li L, Fang L, Wang M, Xu S, Wang G, Zheng J, Li H
iScience 2024 Jan 19;27(1):108597
iScience 2024 Jan 19;27(1):108597
Osteocyte mitochondria inhibit tumor development via STING-dependent antitumor immunity.
Zhou H, Zhang W, Li H, Xu F, Yinwang E, Xue Y, Chen T, Wang S, Wang Z, Sun H, Wang F, Mou H, Yao M, Chai X, Zhang J, Diarra MD, Li B, Zhang C, Gao J, Ye Z
Science advances 2024 Jan 19;10(3):eadi4298
Science advances 2024 Jan 19;10(3):eadi4298
Protective effect of low-intensity pulsed ultrasound on immune checkpoint inhibitor-related myocarditis via fine-tuning CD4(+) T-cell differentiation.
Fu S, Guo Z, Xu X, Li Y, Choi S, Zhao P, Shen W, Gao F, Wang C, Chen S, Li Y, Tian J, Sun P
Cancer immunology, immunotherapy : CII 2024 Jan 18;73(1):15
Cancer immunology, immunotherapy : CII 2024 Jan 18;73(1):15
Uncovering the Therapeutic Potential of Phosphocreatine in Diabetic Retinopathy: Mitigating Mitochondrial Dysfunction and Apoptosis via JAK2/STAT3 Signaling Pathway.
Qaed E, Alyafeai E, Al-Maamari A, Zaky MY, Almoiliqy M, Al-Hamyari B, Qaid A, Yafei S, Aldahmash W, Mahyoub MA, Wang F, Kang L, Tang Z, Zhang J
Journal of molecular neuroscience : MN 2024 Jan 17;74(1):11
Journal of molecular neuroscience : MN 2024 Jan 17;74(1):11
Neutrophil extracellular trap-related mechanisms in acne vulgaris inspire a novel treatment strategy with adipose-derived stem cells.
Yu H, Zhang B, Zhan Y, Yi Y, Jiang Q, Zhang Q, Wu Y, Wu M
Scientific reports 2024 Jan 17;14(1):1521
Scientific reports 2024 Jan 17;14(1):1521
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Tao H, Song SJ, Fan ZW, Li WT, Jin X, Jiang W, Bai J, Shi ZZ
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma.
Chen W, Liao Y, Sun P, Tu J, Zou Y, Fang J, Chen Z, Li H, Chen J, Peng Y, Wen L, Xie X
Journal of translational medicine 2024 Jan 16;22(1):66
Journal of translational medicine 2024 Jan 16;22(1):66
17β-Estradiol inhibits hydrogen peroxide-induced senescence and apoptosis in human umbilical vein endothelial cells by regulating the THBS1/TGF-β/Smad axis.
Lv Y, Huang Y, Fan H, Zhao Y, Ma L, Lan Y, Li C, Chen P, Lou Z, Zhou J
Molecular and cellular endocrinology 2024 Jan 15;580:112111
Molecular and cellular endocrinology 2024 Jan 15;580:112111
ALKBH5 mediates silica particles-induced pulmonary inflammation through increased m(6)A modification of Slamf7 and autophagy dysfunction.
Yin H, Gu P, Xie Y, You X, Zhang Y, Yao Y, Yang S, Wang D, Chen W, Ma J
Journal of hazardous materials 2024 Jan 15;462:132736
Journal of hazardous materials 2024 Jan 15;462:132736
Smyd1: Implications for novel approaches in rhabdomyosarcoma therapy.
Berkholz J, Schmitt A, Fragasso A, Schmid AC, Munz B
Experimental cell research 2024 Jan 15;434(2):113863
Experimental cell research 2024 Jan 15;434(2):113863
Loganin protects against myocardial ischemia-reperfusion injury by modulating oxidative stress and cellular apoptosis via activation of JAK2/STAT3 signaling.
Xia B, Ding J, Li Q, Zheng K, Wu J, Huang C, Liu K, You Q, Yuan X
International journal of cardiology 2024 Jan 15;395:131426
International journal of cardiology 2024 Jan 15;395:131426
Response of lipid metabolism, energy supply, and cell fate in yellowstripe goby (Mugilogobius chulae) exposed to environmentally relevant concentrations atorvastatin.
Zhao Y, Duan C, Zhang H, Gong W, Wang Y, Ren J, Nie X, Li J
Environmental pollution (Barking, Essex : 1987) 2024 Jan 15;341:122991
Environmental pollution (Barking, Essex : 1987) 2024 Jan 15;341:122991
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Peng ML, Zhang LJ, Luo Y, Xu SY, Long XM, Ao JL, Liao SG, Zhu QF, He X, Xu GB
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Wu S, Du W, Wu Z, Wen F, Zhong X, Huang X, Gu H, Wang J
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Design, synthesis and biological evaluation of biaryl amide derivatives against SARS-CoV-2 with dual-target mechanism.
Li J, Zhong X, Li H, Yu Z, Li J, Duan Q, Li Y, Chen F, Wang Y, Wu Z, Liu Y, Peng Z, Song D
European journal of medicinal chemistry 2024 Jan 15;264:115978
European journal of medicinal chemistry 2024 Jan 15;264:115978
Mechanism of action of Shaoyao-Gancao decoction in relieving chronic inflammatory pain via Sema3G protein regulation in the dorsal root ganglion.
Lin R, Gu JG, Wang ZF, Zeng XX, Xiao HW, Chen JC, He J
Heliyon 2024 Jan 15;10(1):e23617
Heliyon 2024 Jan 15;10(1):e23617
Novel molecular classification and prognosis of papillary renal cell carcinoma based on a large-scale CRISPR-Cas9 screening and machine learning.
Liu C, Yuan ZY, Zhang XX, Chang JJ, Yang Y, Sun SJ, Du Y, Zhan HQ
Heliyon 2024 Jan 15;10(1):e23184
Heliyon 2024 Jan 15;10(1):e23184
ALKBH5 is a prognostic factor and promotes the angiogenesis of glioblastoma.
Fan Y, Yan D, Ma L, Liu X, Luo G, Hu Y, Kou X
Scientific reports 2024 Jan 14;14(1):1303
Scientific reports 2024 Jan 14;14(1):1303
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
Wu DZ, Zhu GZ, Zhao K, Gao JW, Cai GX, Li HZ, Huang YS, Tu C, Zhuang JS, Huang ZW, Zhong ZM
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
The anoikis-related gene signature predicts survival and correlates with immune infiltration in osteosarcoma.
Li J, Wang H, Wu F, Yao J, Zhu H, Zhang M
Aging 2024 Jan 12;16(1):665-684
Aging 2024 Jan 12;16(1):665-684
The miR-19a/Cylindromatosis Axis Regulates Pituitary Adenoma Bone Invasion by Promoting Osteoclast Differentiation.
Lei Z, Wang Q, Jiang Q, Liu H, Xu L, Kang H, Li F, Huang Y, Lei T
Cancers 2024 Jan 11;16(2)
Cancers 2024 Jan 11;16(2)
Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response.
Sheng Y, Lei K, Sun C, Liu J, Tu Z, Zhu X, Huang K
Aging 2024 Jan 11;16(1):226-245
Aging 2024 Jan 11;16(1):226-245
Amyloid aggregates induced by the p53-R280T mutation lead to loss of p53 function in nasopharyngeal carcinoma.
Li J, Guo M, Chen L, Chen Z, Fu Y, Chen Y
Cell death & disease 2024 Jan 11;15(1):35
Cell death & disease 2024 Jan 11;15(1):35
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin.
Wu LR, Peng QY, Li XJ, Guo MY, He JQ, Ying HZ, Yu CH
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117056
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117056
Qinzhizhudan formula dampens inflammation in microglia polarization of vascular dementia rats by blocking MyD88/NF-κB signaling pathway: Through integrating network pharmacology and experimental validation.
Chen CA, Li CX, Zhang ZH, Xu WX, Liu SL, Ni WC, Wang XQ, Cheng FF, Wang QG
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116769
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116769
Synergistic cerium oxide nanozymes: targeting DNA damage and alleviating tumor hypoxia for improved NSCLC radiotherapy efficiency.
Liu J, Liu C, Tang J, Chen Q, Yu Y, Dong Y, Hao J, Wu W
Journal of nanobiotechnology 2024 Jan 10;22(1):25
Journal of nanobiotechnology 2024 Jan 10;22(1):25
GDF11 mediates H(2)S to prevent chronic stress-induced cognitive impairment by reducing hippocampal NLRP3/caspase-1-dependent pyroptosis.
Wang B, Chen SM, Yang SQ, Jiang JM, Zhang P, Zou W, Tang XQ
Journal of affective disorders 2024 Jan 1;344:600-611
Journal of affective disorders 2024 Jan 1;344:600-611
Lycium barbarum polysaccharides attenuate oxidative stress and mitochondrial toxicity induced by mixed plasticizers in HepG2 cells through activation of Nrf2.
Zhou L, Yang J, Liu H, Rang Y, Xu L, Wang X, Li Y, Liu C
Life sciences 2024 Jan 1;336:122346
Life sciences 2024 Jan 1;336:122346
Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology.
Attiogbe MKI, Zhao HY, Wang J, Huang TT, Yan PP, Liu YN, Li W, Cao L, Zhang SQ, Cao YX
Life sciences 2024 Jan 1;336:122308
Life sciences 2024 Jan 1;336:122308
Targeting HIF-1α alleviates the inflammatory responses and rebuilds the CD4(+) T cell subsets balance in the experimental autoimmune myasthenia gravis inflammation model via regulating cellular and humoral immunity.
Yu L, Ran H, Lu Y, Ma Q, Huang H, Liu W
Life sciences 2024 Jan 1;336:122287
Life sciences 2024 Jan 1;336:122287
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Zhu M, Yan M, Musa M, Li Y, Zhang Y, Zou X
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Nitro-oleic acid ameliorates erectile dysfunction in a streptozotocin-induced rat model of diabetes by inhibiting oxidative stress and apoptosis and activating the NO/cGMP pathway.
Zhao CB, Chen WB, Wang WZ, Gong FX, Fan CQ, Li Y, Lan T, Wang WJ, Yuan MZ
Asian journal of andrology 2024 Jan 1;26(1):57-66
Asian journal of andrology 2024 Jan 1;26(1):57-66
Neuronal pyroptosis mediated by STAT3 in early brain injury after subarachnoid hemorrhage.
Tang S, Lai N, Xu L
Brain research 2024 Jan 1;1822:148666
Brain research 2024 Jan 1;1822:148666
Inhibition of SOCS3 signaling in the nucleus tractus solitarii and retrotrapezoid nucleus alleviates hypoventilation in diet-induced obese male mice.
Hao Y, Wei Z, Wang S, An P, Huang Y, Yu L, Zhu M, Yu H, Yuan F, Wang S
Brain research 2024 Jan 1;1822:148608
Brain research 2024 Jan 1;1822:148608
Hydrogen sulfide attenuates atherosclerosis induced by low shear stress by sulfhydrylating endothelium NFIL3 to restrain MEST mediated endothelial mesenchymal transformation.
Zhou K, Luo W, Gui DD, Ren Z, Wei DH, Liu LS, Li GH, Tang ZH, Xiong WH, Hu HJ, Jiang ZS
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Ye F, Liu D, Zhang J
Tissue & cell 2024 Feb;86:102290
Tissue & cell 2024 Feb;86:102290
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions.
Wang Z, Cui F, Chen Y, Liu H, Zhang Y, Shi Y, Zhang Y, Wang Y, Liang N, Xu L, Liu Y, Liu Z, Shi W
Tissue & cell 2024 Feb;86:102284
Tissue & cell 2024 Feb;86:102284
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
Huang H, Yan J, Xu X, Feng Y, Liu H, Liu J, Xie M, Chen L, Xiang D, Peng W, Zeng L, Zeng Y, Chen F, Zhang S, Liu Q
Drug development research 2024 Feb;85(1):e22140
Drug development research 2024 Feb;85(1):e22140
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
Xu H, Fu J, Tu Q, Shuai Q, Chen Y, Wu F, Cao Z
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
ACE2 activation alleviates sepsis-induced cardiomyopathy by promoting MasR-Sirt1-mediated mitochondrial biogenesis.
Wan TT, Li Y, Li JX, Xiao X, Liu L, Li HH, Guo SB
Archives of biochemistry and biophysics 2024 Feb;752:109855
Archives of biochemistry and biophysics 2024 Feb;752:109855
PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma.
Li Q, Li J, Wang J, Wang J, Lu T, Jia Y, Sun H, Ma X
Molecular carcinogenesis 2024 Feb;63(2):253-265
Molecular carcinogenesis 2024 Feb;63(2):253-265
7-Dehydrocholesterol dictates ferroptosis sensitivity.
Li Y, Ran Q, Duan Q, Jin J, Wang Y, Yu L, Wang C, Zhu Z, Chen X, Weng L, Li Z, Wang J, Wu Q, Wang H, Tian H, Song S, Shan Z, Zhai Q, Qin H, Chen S, Fang L, Yin H, Zhou H, Jiang X, Wang P
Nature 2024 Feb;626(7998):411-418
Nature 2024 Feb;626(7998):411-418
Rho GTPase-activating protein 1 promotes hepatocellular carcinoma progression via modulation by CircPIP5K1A/MiR-101-3p.
Xu Y, Liu X, Cao J, Wu Y, Jiang Q, Luo B
Hepatology research : the official journal of the Japan Society of Hepatology 2024 Feb;54(2):174-188
Hepatology research : the official journal of the Japan Society of Hepatology 2024 Feb;54(2):174-188
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy.
Ma Z, Lu H, Feng X, Du T, Li J, Zhang Q, Gu X, Shao Y, Jing X, Su C
International journal of molecular medicine 2024 Feb;53(2)
International journal of molecular medicine 2024 Feb;53(2)
Reticulon 3 regulates sphingosine-1-phosphate synthesis in endothelial cells to control blood pressure.
Jin JY, Chang SH, Chen YQ, Liu MW, Dong Y, Liu JS, Wang Q, Huang H, Fan LL, Xiang R
MedComm 2024 Feb;5(2):e480
MedComm 2024 Feb;5(2):e480
IRF4 Participates in Pulmonary Fibrosis Induced by Silica Particles through Regulating Macrophage Polarization and Fibroblast Activation.
Jiao B, Zhang Q, Jin C, Yu H, Wu Q
Inflammation 2024 Feb;47(1):45-59
Inflammation 2024 Feb;47(1):45-59
Synergistic antitumor efficacy of gemcitabine and cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via Sp1-SAT1-polyamine metabolism pathway.
Wei W, Lu Y, Hu Q, Yin J, Wang Y, Zhang H, Zhao Q, Liu L
Cellular oncology (Dordrecht, Netherlands) 2024 Feb;47(1):321-341
Cellular oncology (Dordrecht, Netherlands) 2024 Feb;47(1):321-341
hPMSCs Regulate the Level of TNF-α and IL-10 in Th1 Cells and Improve Hepatic Injury in a GVHD Mouse Model via CD73/ADO/Fyn/Nrf2 Axis.
Zhang H, Han K, Li H, Zhang J, Zhao Y, Wu Y, Wang B, Ma J, Luan X
Inflammation 2024 Feb;47(1):244-263
Inflammation 2024 Feb;47(1):244-263
Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway.
Wu Z, Liu Q, Cao Z, Li H, Zhou Y, Zhang P
Immunopharmacology and immunotoxicology 2024 Feb;46(1):86-92
Immunopharmacology and immunotoxicology 2024 Feb;46(1):86-92
C-C Motif Chemokine 2 Regulates Macrophage Polarization and Contributes to Myocardial Infarction Healing.
Chen L, Pan D, Zhang Y, Zhang E, Ma L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 Feb;44(2):68-79
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 Feb;44(2):68-79
Activation of autophagy promotes the inhibitory effect of curcumin analog EF-24 against MDA-MB-231 cancer cells.
Zhao YY, Li J, Wang HQ, Zheng HB, Ma SW, Zhou GZ
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23642
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23642
Immune Response Gene-1 [IRG1]/itaconate protect against multi-organ injury via inhibiting gasdermin D-mediated pyroptosis and inflammatory response.
Yang W, Wang Y, Huang Y, Wang T, Li C, Zhang P, Liu W, Yin Y, Li R, Tao K
Inflammopharmacology 2024 Feb;32(1):419-432
Inflammopharmacology 2024 Feb;32(1):419-432
Ketone bodies promote epididymal white adipose expansion to alleviate liver steatosis in response to a ketogenic diet.
Zhao MF, Zhang XG, Tang YP, Zhu YX, Nie HY, Bu DD, Fang L, Li CJ
The Journal of biological chemistry 2024 Feb;300(2):105617
The Journal of biological chemistry 2024 Feb;300(2):105617
Piperine improves levodopa availability in the 6-OHDA-lesioned rat model of Parkinson's disease by suppressing gut bacterial tyrosine decarboxylase.
Hu X, Yu L, Li Y, Li X, Zhao Y, Xiong L, Ai J, Chen Q, Wang X, Chen X, Ba Y, Wang Y, Wu X
CNS neuroscience & therapeutics 2024 Feb;30(2):e14383
CNS neuroscience & therapeutics 2024 Feb;30(2):e14383
Electroacupuncture pretreatment preserves telomerase reverse transcriptase function and alleviates postoperative cognitive dysfunction by suppressing oxidative stress and neuroinflammation in aged mice.
Wang W, Chen C, Wang Q, Ma JG, Li YS, Guan Z, Wang R, Chen X
CNS neuroscience & therapeutics 2024 Feb;30(2):e14373
CNS neuroscience & therapeutics 2024 Feb;30(2):e14373
Roles of lncLingo2 and its derived miR-876-5p in the acquisition of opioid reinforcement.
Yang H, Zhang X, Zhang M, Lu Y, Xie B, Sun S, Yu H, Cong B, Luo Y, Ma C, Wen D
Addiction biology 2024 Feb;29(2):e13375
Addiction biology 2024 Feb;29(2):e13375
Oncogenic and immunological roles of RACGAP1 in pan-cancer and its potential value in nasopharyngeal carcinoma.
Zheng CS, Huang WM, Xia HM, Mi JL, Li YQ, Liang HQ, Zhou L, Lu ZX, Wu F
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):243-266
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):243-266
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
Cheng C, Tang S, Cui S, Yang T, Li L, Zhai M, Wei F, Ding G
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
Exosome-delivered miR-410-3p reverses epithelial-mesenchymal transition, migration and invasion of trophoblasts in spontaneous abortion.
Chen ZY, Li Z, Zong Y, Xia B, Luo SP, Deng GP, Gao J
Journal of cellular and molecular medicine 2024 Feb;28(3):e18097
Journal of cellular and molecular medicine 2024 Feb;28(3):e18097
Alleviating 3-MCPD-induced male reproductive toxicity: Mechanistic insights and resveratrol intervention.
Wang KL, Chiang YF, Huang KC, Chen HY, Ali M, Hsia SM
Ecotoxicology and environmental safety 2024 Feb;271:115978
Ecotoxicology and environmental safety 2024 Feb;271:115978
In vitro and in vivo immunomodulatory activity of acetylated polysaccharides from Cyclocarya paliurus leaves.
Zhang Y, Zhao M, He J, Chen L, Wang W
International journal of biological macromolecules 2024 Feb;259(Pt 1):129174
International journal of biological macromolecules 2024 Feb;259(Pt 1):129174
Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation.
Liu Y, Yang M, Fan L, He Y, Dai E, Liu M, Jiang L, Yang Z, Li S
International journal of biological macromolecules 2024 Feb;258(Pt 1):128570
International journal of biological macromolecules 2024 Feb;258(Pt 1):128570
Trichinella spiralis cathepsin B bound and degraded host's intestinal type I collagen.
Zao YJ, Cheng G, Feng MM, Wang YX, Zhang ZF, Zhang X, Jiang P
International journal of biological macromolecules 2024 Feb;257(Pt 2):128728
International journal of biological macromolecules 2024 Feb;257(Pt 2):128728
m5C modification of LINC00324 promotes angiogenesis in glioma through CBX3/VEGFR2 pathway.
Pan A, Xue Y, Ruan X, Dong W, Wang D, Liu Y, Liu L, Lin Y, E T, Lin H, Xu H, Liu X, Wang P
International journal of biological macromolecules 2024 Feb;257(Pt 1):128409
International journal of biological macromolecules 2024 Feb;257(Pt 1):128409
KIF4A functions as a diagnostic and prognostic biomarker and regulates tumor immune microenvironment in skin cutaneous melanoma.
Zeng S, Wang Q, Zhou R, Wang D
Pathology, research and practice 2024 Feb;254:155166
Pathology, research and practice 2024 Feb;254:155166
KBTBD2 promotes proliferation and migration of gastric cancer via activating EGFR signaling pathway.
Ding J, Gao W, Yang H, Duan L, Sun D, Liu L, Qu X, Yu H, Xu B, Zhao S, Wang L, Chai J
Pathology, research and practice 2024 Feb;254:155095
Pathology, research and practice 2024 Feb;254:155095
Disrupted HSF1 regulation in normal and exceptional brain aging.
Trivedi R, Knopf B, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
Biogerontology 2024 Feb;25(1):147-160
Biogerontology 2024 Feb;25(1):147-160
AGK2 pre-treatment protects against thioacetamide-induced acute liver failure via regulating the MFN2-PERK axis and ferroptosis signaling pathway.
Zhang QQ, Chen Q, Cao P, Shi CX, Zhang LY, Wang LW, Gong ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Feb;23(1):43-51
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Feb;23(1):43-51
In vitro and in vivo biological evaluation of Lappaconitine derivatives as potential anti-inflammatory agents.
Xiao Y, Han M, Chen Y, Li YZ, Zhang YY, Chen L, Huang S, Zhou XL
Chemistry & biodiversity 2024 Feb;21(2):e202301761
Chemistry & biodiversity 2024 Feb;21(2):e202301761
MMP14(high) macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis.
Peng D, Li J, Li Y, Bai L, Xiong A, He X, Li X, Ran Q, Zhang L, Jiang M, Wang J, Leung EL, Yang P, Li G
Pharmacological research 2024 Feb;200:107070
Pharmacological research 2024 Feb;200:107070
Paxillin/HDAC6 regulates microtubule acetylation to promote directional migration of keratinocytes driven by electric fields.
Liu L, Liu X, Chen Y, Kong M, Zhang J, Jiang M, Zhou H, Yang J, Chen X, Zhang Z, Wu C, Jiang X, Zhang J
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119628
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119628
Pan-cancer analysis of PLAU indicates its potential prognostic value and correlation with neutrophil infiltration in BLCA.
Shi K, Zhou J, Li M, Yan W, Zhang J, Zhang X, Jiang L
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166965
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166965
Sodium butyrate alleviates lead-induced neuroinflammation and improves cognitive and memory impairment through the ACSS2/H3K9ac/BDNF pathway.
Li Y, Liu A, Chen K, Li L, Zhang X, Zou F, Zhang X, Meng X
Environment international 2024 Feb;184:108479
Environment international 2024 Feb;184:108479
Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway.
Chen P, Yuan M, Yao L, Xiong Z, Liu P, Wang Z, Jiang Y, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116133
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116133
Periplaneta americana extract promotes hard palate mucosal wound healing via the PI3K/AKT signaling pathway in male mice.
Zhao B, Xu J, Wang Y, Li Y, Li Y, Zhang X, Zhang S, Yu L, Yuan Q
Archives of oral biology 2024 Feb;158:105856
Archives of oral biology 2024 Feb;158:105856
Reduced Bioactive Microbial Products (Pathogen-Associated Molecular Patterns) Contribute to Dysregulated Immune Responses and Impaired Healing in Infected Wounds in Mice with Diabetes.
Roy R, Mahmud F, Zayas J, Kuzel TM, Reiser J, Shafikhani SH
The Journal of investigative dermatology 2024 Feb;144(2):387-397.e11
The Journal of investigative dermatology 2024 Feb;144(2):387-397.e11
Penicimides A and B, two novel diels-alder [4 + 2] cycloaddition ergosteroids from Penicillium herquei.
Deng M, Xiao Y, Wang S, Zhang M, Qiao Y, Huang S, Xie J, Zhou X
Bioorganic chemistry 2024 Feb;143:107025
Bioorganic chemistry 2024 Feb;143:107025
Tanshinone IIA ameliorates energy metabolism dysfunction of pulmonary fibrosis using (13)C metabolic flux analysis.
Shan B, Zhou H, Guo C, Liu X, Wu M, Zhai R, Chen J
Journal of pharmaceutical analysis 2024 Feb;14(2):244-258
Journal of pharmaceutical analysis 2024 Feb;14(2):244-258
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Hui H, Wang Z, Zhao X, Xu L, Yin L, Wang F, Qu L, Peng J
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Assessing the mitochondrial safety profile of the molnupiravir active metabolite, β-d-N4-hydroxycytidine (NHC), in the physiologically relevant HepaRG model.
Kiy RT, Khoo SH, Chadwick AE
Toxicology research 2024 Feb;13(1):tfae012
Toxicology research 2024 Feb;13(1):tfae012
Palmatine ameliorated lipopolysaccharide-induced sepsis-associated encephalopathy mice by regulating the microbiota-gut-brain axis.
Xu Y, Shen B, Pan X, Liu C, Wang Y, Chen X, Wang T, Chen G, Chen J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155307
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155307
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
Liu Y, Wu J, Tan L, Li Z, Gao P, He S, Wang Q, Tang D, Wang C, Wang F, Li P, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation.
Chen H, Hu Q, Wen T, Luo L, Liu L, Wang L, Shen X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155263
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155263
Fucoidan alleviated dextran sulfate sodium-induced ulcerative colitis with improved intestinal barrier, reshaped gut microbiota composition, and promoted autophagy in male C57BL/6 mice.
Li S, Qian Q, Yang H, Wu Z, Xie Y, Yin Y, Cui Y, Li X
Nutrition research (New York, N.Y.) 2024 Feb;122:1-18
Nutrition research (New York, N.Y.) 2024 Feb;122:1-18
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
Wang S, Huang X, Zhang G, Chen Z, Guan H, Zhou W
Cellular signalling 2024 Feb;114:110998
Cellular signalling 2024 Feb;114:110998
G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer.
Zheng X, Chen J, Deng M, Ning K, Peng Y, Liu Z, Li X, Zhou Z, Tang H, Li Y, Kang T, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305922
Rosuvastatin Enhances Lymphangiogenesis after Myocardial Infarction by Regulating the miRNAs/Vascular Endothelial Growth Factor Receptor 3 (miRNAs/VEGFR3) Pathway.
Lian Z, Yu SR, Cui YX, Li SF, Su LN, Song JX, Lee CY, Chen QX, Chen H
ACS pharmacology & translational science 2024 Feb 9;7(2):335-347
ACS pharmacology & translational science 2024 Feb 9;7(2):335-347
Multi-omics sequencing revealed endostar combined with cisplatin treated non small cell lung cancer via anti-angiogenesis.
Wang Y, Ren H
BMC cancer 2024 Feb 8;24(1):187
BMC cancer 2024 Feb 8;24(1):187
An Esterase-Responsive SLC7A11 shRNA Delivery System Induced Ferroptosis and Suppressed Hepatocellular Carcinoma Progression.
Zhang H, Wang J, Xiang X, Xie C, Lu X, Guo H, Sun Y, Shi Z, Song H, Qiu N, Xu X
Pharmaceutics 2024 Feb 8;16(2)
Pharmaceutics 2024 Feb 8;16(2)
Demyelination in the medial prefrontal cortex by withdrawal from chronic nicotine causes impaired cognitive memory.
Huang B, Chen Z, Huang F, Gao F, Chen J, Liu P, Lu Z, Chen W, Wu J
Progress in neuro-psychopharmacology & biological psychiatry 2024 Feb 8;129:110901
Progress in neuro-psychopharmacology & biological psychiatry 2024 Feb 8;129:110901
METTL14 enhances the m6A modification level of lncRNA MSTRG.292666.16 to promote the progression of non-small cell lung cancer.
Ji X, Wan X, Sun H, Deng Q, Meng S, Xie B, Zhou S
Cancer cell international 2024 Feb 7;24(1):61
Cancer cell international 2024 Feb 7;24(1):61
Dapagliflozin improves podocytes injury in diabetic nephropathy via regulating cholesterol balance through KLF5 targeting the ABCA1 signalling pathway.
Sun J, Zhang X, Wang S, Chen D, Shu J, Chong N, Wang Q, Xu Y
Diabetology & metabolic syndrome 2024 Feb 7;16(1):38
Diabetology & metabolic syndrome 2024 Feb 7;16(1):38
The role of extracellular vesicle fusion with target cells in triggering systemic inflammation.
Papareddy P, Tapken I, Kroh K, Varma Bhongir RK, Rahman M, Baumgarten M, Cim EI, Györffy L, Smeds E, Neumann A, Veerla S, Olinder J, Thorlacus H, Ryden C, Bartakova E, Holub M, Herwald H
Nature communications 2024 Feb 7;15(1):1150
Nature communications 2024 Feb 7;15(1):1150
Trimethylamine N-Oxide Improves Exercise Performance by Reducing Oxidative Stress through Activation of the Nrf2 Signaling Pathway.
Zou H, Zhou Y, Gong L, Huang C, Liu X, Lu R, Yu J, Kong Z, Zhang Y, Lin D
Molecules (Basel, Switzerland) 2024 Feb 6;29(4)
Molecules (Basel, Switzerland) 2024 Feb 6;29(4)
Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice.
Li J, Liu Y, He J, Wu Z, Wang F, Huang J, Zheng L, Luo T
Journal of ovarian research 2024 Feb 6;17(1):35
Journal of ovarian research 2024 Feb 6;17(1):35
Minocycline alleviates LPS-induced cognitive dysfunction in mice by inhibiting the NLRP3/caspase-1 pathway.
Zhan F, Dong Y, Zhou L, Li X, Zhou Z, Xu G
Aging 2024 Feb 6;16(3):2989-3006
Aging 2024 Feb 6;16(3):2989-3006
Cediranib ameliorates portal hypertensive syndrome via inhibition of VEGFR-2 signaling in cirrhotic rats.
Fan Q, Wu G, Chen M, Luo G, Wu Z, Huo H, Li H, Zheng L, Luo M
European journal of pharmacology 2024 Feb 5;964:176278
European journal of pharmacology 2024 Feb 5;964:176278
Berberine inhibits NLRP3 inflammasome activation by regulating mTOR/mtROS axis to alleviate diabetic cardiomyopathy.
Zhong C, Xie Y, Wang H, Chen W, Yang Z, Zhang L, Deng Q, Cheng T, Li M, Ju J, Liu Y, Liang H
European journal of pharmacology 2024 Feb 5;964:176253
European journal of pharmacology 2024 Feb 5;964:176253
Adelmidrol ameliorates liver ischemia-reperfusion injury through activating Nrf2 signaling pathway.
Wu M, Liu X, Yu Q, Shi J, Guo W, Zhang S
European journal of pharmacology 2024 Feb 5;964:176224
European journal of pharmacology 2024 Feb 5;964:176224
Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation.
Zuo Y, Long Z, Li R, Le Y, Zhang S, He H, Yan L
European journal of medicinal chemistry 2024 Feb 5;265:116106
European journal of medicinal chemistry 2024 Feb 5;265:116106
Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth.
Wu J, Qin C, Tian F, Liu X, Hu J, Wu F, Chen C, Lin Y
BMC medicine 2024 Feb 5;22(1):57
BMC medicine 2024 Feb 5;22(1):57
Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.
Wang X, Zhang Y, Yu J, Ma Y, Xu Y, Shi J, Qi Z, Liu X
BMC genomics 2024 Feb 3;25(1):139
BMC genomics 2024 Feb 3;25(1):139
Effects of exosomes derived from platelet-rich plasma on osteogenic differentiation of dental pulp stem cells.
Mo C, Liu Z, Lin Y, A Bu Du Xi Ku NEBY, Li S, Ruan Q, Liu C, Xu S, Wen J
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Feb 29;70(2):227-234
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Feb 29;70(2):227-234
Identification and validation of STAT4 as a prognostic biomarker in acute myeloid leukemia.
Li C, Zhao J, Kang B, Li S, Tang J, Dong D, Chen Y
Bioscience reports 2024 Feb 29;44(2)
Bioscience reports 2024 Feb 29;44(2)
Deciphering a crucial dimeric interface governing Norrin dimerization and the pathogenesis of familial exudative vitreoretinopathy.
Zhao R, Liu M, Dai E, Chen C, Lv L, Peng L, He Y, Li S, Yang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23493
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23493
Comprehensive analysis of ovarian granulosa cell proteomics and phosphoproteomics in PCOS patients without insulin resistance.
Yang X, Liu P, He H, Qi D, Yan L
Molecular human reproduction 2024 Feb 29;30(3)
Molecular human reproduction 2024 Feb 29;30(3)
Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma.
Xiong G, Xie N, Nie M, Ling R, Yun B, Xie J, Ren L, Huang Y, Wang W, Yi C, Zhang M, Xu X, Zhang C, Zou B, Zhang L, Liu X, Huang H, Chen D, Cao W, Wang C
International journal of oral science 2024 Feb 29;16(1):21
International journal of oral science 2024 Feb 29;16(1):21
Akkermansia muciniphila Is Beneficial to a Mouse Model of Parkinson's Disease, via Alleviated Neuroinflammation and Promoted Neurogenesis, with Involvement of SCFAs.
Qiao CM, Huang WY, Zhou Y, Quan W, Niu GY, Li T, Zhang MX, Wu J, Zhao LP, Zhao WJ, Cui C, Shen YQ
Brain sciences 2024 Feb 29;14(3)
Brain sciences 2024 Feb 29;14(3)
The diagnostic, prognostic, drug sensitivity and ceRNA internet of PPP4R1 in liver hepatocellular carcinoma (LIHC).
Li X, Pan Y, Feng S, Xing W, Lin B, Li W, Li M, Zhu M
Translational cancer research 2024 Feb 29;13(2):594-612
Translational cancer research 2024 Feb 29;13(2):594-612
Elevated SLC7A2 expression is associated with an abnormal neuroinflammatory response and nitrosative stress in Huntington's disease.
Gaudet ID, Xu H, Gordon E, Cannestro GA, Lu ML, Wei J
Journal of neuroinflammation 2024 Feb 28;21(1):59
Journal of neuroinflammation 2024 Feb 28;21(1):59
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
Zhang W, Huang J, Shi J
Brain sciences 2024 Feb 28;14(3)
Brain sciences 2024 Feb 28;14(3)
ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation.
Shen Y, Zheng LL, Fang CY, Xu YY, Wang C, Li JT, Lei MZ, Yin M, Lu HJ, Lei QY, Qu J
Cell reports 2024 Feb 27;43(2):113720
Cell reports 2024 Feb 27;43(2):113720
DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target.
Chen M, Zhang S, Wang F, He J, Jiang W, Zhang L
Journal of translational medicine 2024 Feb 27;22(1):209
Journal of translational medicine 2024 Feb 27;22(1):209
TBC1D23 mediates Golgi-specific LKB1 signaling.
Tu Y, Yang Q, Tang M, Gao L, Wang Y, Wang J, Liu Z, Li X, Mao L, Jia RZ, Wang Y, Tang TS, Xu P, Liu Y, Dai L, Jia D
Nature communications 2024 Feb 27;15(1):1785
Nature communications 2024 Feb 27;15(1):1785
ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1.
Huang X, Balmer S, Lyu C, Xiang Y, Malik V, Wang H, Zhang Y, Cai B, Xie W, Hadjantonakis AK, Zhou H, Wang J
Developmental cell 2024 Feb 26;59(4):465-481.e6
Developmental cell 2024 Feb 26;59(4):465-481.e6
EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells.
Tian Q, Chen JH, Ding Y, Wang XY, Qiu JY, Cao Q, Zhuang LL, Jin R, Zhou GP
Molecular biology reports 2024 Feb 26;51(1):365
Molecular biology reports 2024 Feb 26;51(1):365
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling.
Yuan Y, Zhang XF, Li YC, Chen HQ, Wen T, Zheng JL, Zhao ZY, Hu QY
World journal of stem cells 2024 Feb 26;16(2):207-227
World journal of stem cells 2024 Feb 26;16(2):207-227
The P124A mutation of SRP14 alters its migration on SDS-PAGE without impacting its function.
Liu Y, Zhou J
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):315-322
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):315-322
Fisetin suppresses chondrocyte senescence and attenuates osteoarthritis progression by targeting sirtuin 6.
Wang X, Li X, Zhou J, Lei Z, Yang X
Chemico-biological interactions 2024 Feb 25;390:110890
Chemico-biological interactions 2024 Feb 25;390:110890
Ferritinophagy-mediated ferroptosis of spermatogonia is involved in busulfan-induced oligospermia in the mice.
Xu J, Zhang L, Si Y, Huang W, Liu R, Liu Z, Jiang Z, Xu F
Chemico-biological interactions 2024 Feb 25;390:110870
Chemico-biological interactions 2024 Feb 25;390:110870
DPPA2/4 Promote the Pluripotency and Proliferation of Bovine Extended Pluripotent Stem Cells by Upregulating the PI3K/AKT/GSK3β/β-Catenin Signaling Pathway.
Fang S, Wang J, Liu G, Qu B, Chunyu J, Xu W, Xiang J, Li X
Cells 2024 Feb 23;13(5)
Cells 2024 Feb 23;13(5)
Hsa_circ_0005397 promotes hepatocellular carcinoma progression through EIF4A3.
Yuan LX, Luo M, Liu RY, Wang HX, Ju LL, Wang F, Cao YL, Wang ZC, Chen L
BMC cancer 2024 Feb 21;24(1):239
BMC cancer 2024 Feb 21;24(1):239
Lysine Demethylase 4A is a Centrosome Associated Protein Required for Centrosome Integrity and Genomic Stability.
Chowdhury P, Wang X, Love JF, Vargas-Hernandez S, Nakatani Y, Grimm SL, Mezquita D, Mason FM, Martinez ED, Coarfa C, Walker CL, Gustavsson AK, Dere R
bioRxiv : the preprint server for biology 2024 Feb 21;
bioRxiv : the preprint server for biology 2024 Feb 21;
In Vitro Ferroptotic and Antitumor Effect of Free or Liposome-Encapsulated Artesunate in Papillary Thyroid Cancer Cells.
Sun L, Zheng G, Zhou M, Zhang Y, Yang Y, Zhang S, Gao L
ACS omega 2024 Feb 20;9(7):7463-7470
ACS omega 2024 Feb 20;9(7):7463-7470
Hsa_circ_0007990 promotes breast cancer growth via inhibiting YBX1 protein degradation to activate E2F1 transcription.
Xu T, Xiong M, Hong Q, Pan B, Xu M, Wang Y, Sun Y, Sun H, Pan Y, Wang S, He B
Cell death & disease 2024 Feb 20;15(2):153
Cell death & disease 2024 Feb 20;15(2):153
Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway.
Wang G, Li R, Feng C, Li K, Liu S, Fu Q
Cell death discovery 2024 Feb 20;10(1):92
Cell death discovery 2024 Feb 20;10(1):92
Transcriptomics analysis revealed that TAZ regulates the proliferation of KIRC cells through mitophagy.
He Z, Shi J, Zhu B, Tian Z, Zhang Z
BMC cancer 2024 Feb 19;24(1):229
BMC cancer 2024 Feb 19;24(1):229
In Vitro Insights into the Role of 7,8-Epoxy-11-Sinulariolide Acetate Isolated from Soft Coral Sinularia siaesensis in the Potential Attenuation of Inflammation and Osteoclastogenesis.
Ke LM, Yu DD, Su MZ, Cui L, Guo YW
Marine drugs 2024 Feb 19;22(2)
Marine drugs 2024 Feb 19;22(2)
5'-Cytimidine Monophosphate Ameliorates H(2)O(2)-Induced Muscular Atrophy in C2C12 Myotubes by Activating IRS-1/Akt/S6K Pathway.
Wu X, Zhu N, He L, Xu M, Li Y
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins.
Chen TQ, Huang HJ, Zhu SX, Chen XT, Pu KJ, Wang D, An Y, Lian JY, Sun YM, Chen YQ, Wang WT
Experimental hematology & oncology 2024 Feb 19;13(1):18
Experimental hematology & oncology 2024 Feb 19;13(1):18
Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice.
Liu R, Shang W, Liu Y, Xie Y, Luan J, Zhang T, Ma Y, Wang Z, Sun Y, Song X, Han F
Cell death discovery 2024 Feb 19;10(1):89
Cell death discovery 2024 Feb 19;10(1):89
Dendrobium officinale Polysaccharides as a Natural Functional Component for Acetic-Acid-Induced Gastric Ulcers in Rats.
Zhang M, Xu L, Chen L, Wu H, Jia L, Zhu H
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Expanding the Genetic Code of Xenopus laevis Embryos.
Brown W, Davidson LA, Deiters A
ACS chemical biology 2024 Feb 16;19(2):516-525
ACS chemical biology 2024 Feb 16;19(2):516-525
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Li T, Yuan J, Xu P, Jia J, Zhao J, Zhang J, Ding R, Zhao X, He D, Wu T, Cheng X
Aging 2024 Feb 16;16(4):3694-3715
Aging 2024 Feb 16;16(4):3694-3715
Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa.
Vasudevan S, Senapati S, Pendergast M, Park PS
Nature communications 2024 Feb 16;15(1):1451
Nature communications 2024 Feb 16;15(1):1451
G-protein-coupled estrogen receptor 1 promotes peritoneal metastasis of gastric cancer through nicotinamide adenine dinucleotide kinase 1-mediated redox modulation.
Wu T, Ding K, Wang C, Lin G, Xie C, Chen X, Li Q, Yu F, Mao Y, Hong W, Lu L, Li S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 15;38(3):e23449
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 15;38(3):e23449
Protein 4.1R regulates M1 macrophages polarization via glycolysis, alleviating sepsis-induced liver injury in mice.
Sang SY, Wang YJ, Liang T, Liu Y, Liu JJ, Li H, Liu X, Kang QZ, Wang T
International immunopharmacology 2024 Feb 15;128:111546
International immunopharmacology 2024 Feb 15;128:111546
The cGAS-STING pathway promotes the development of preeclampsia by upregulating autophagy: Mechanisms and implications.
Sun J, Yu M, Du W, Zhu S, Chen Z, Tao J, Zhou Y, Chen Q, Zhao Y, Zhang Q
International immunopharmacology 2024 Feb 15;128:111531
International immunopharmacology 2024 Feb 15;128:111531
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
Li Q, Xiao C, Gu J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2024 Feb 15;128:111459
International immunopharmacology 2024 Feb 15;128:111459
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
Xie W, Li F, Han Y, Chi X, Qin Y, Ye F, Li Z, Xiao J
Heliyon 2024 Feb 15;10(3):e25906
Heliyon 2024 Feb 15;10(3):e25906
Characterization and verification of CAF-relevant prognostic gene signature to aid therapy in bladder cancer.
Zhou H, Li R, Liu J, Long J, Chen T
Heliyon 2024 Feb 15;10(3):e23873
Heliyon 2024 Feb 15;10(3):e23873
Puerarin Ameliorated PCOS through Preventing Mitochondrial Dysfunction Dependent on the Maintenance of Intracellular Calcium Homeostasis.
Wang YS, Li BY, Xing YF, Huang JC, Chen ZS, Yue L, Zou YG, Guo B
Journal of agricultural and food chemistry 2024 Feb 14;72(6):2963-2976
Journal of agricultural and food chemistry 2024 Feb 14;72(6):2963-2976
Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.
Pan YD, Zhang Y, Zheng WY, Zhu MZ, Li HY, Ouyang WJ, Wen QQ, Zhu XH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Feb 14;44(7)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Feb 14;44(7)
The involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells.
Yao L, Xu W, Liu L, Xu X, Xi H, Xue B, Cao X, Lin S, Piao G, Sun J, Wang X
BMC oral health 2024 Feb 14;24(1):238
BMC oral health 2024 Feb 14;24(1):238
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
Liu Y, He J, Li M, Ren K, Zhao Z
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
Identification of BMAL1-Regulated circadian genes in mouse liver and their potential association with hepatocellular carcinoma: Gys2 and Upp2 as promising candidates.
Zhao H, Han G, Jiang Z, Gao D, Zhang H, Yang L, Ma T, Gao L, Wang A, Chao HW, Li Q, Jin Y, Chen H
Biochemical and biophysical research communications 2024 Feb 12;696:149422
Biochemical and biophysical research communications 2024 Feb 12;696:149422
FOXM1 promote the growth and metastasis of uveal melanoma cells by regulating CDK2 expression.
Bai X, Li S, Luo Y
International ophthalmology 2024 Feb 11;44(1):55
International ophthalmology 2024 Feb 11;44(1):55
ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling.
Zhu X, Zhang Y, Bian R, Zhu J, Shi W, Ye Y
Cancers 2024 Feb 11;16(4)
Cancers 2024 Feb 11;16(4)
Pharmacological effects and mechanism of Maxing Shigan decoction in the treatment of Pseudomonas aeruginosa pneumonia.
Xu Y, Bao L, Cao S, Pang B, Zhang J, Zhang Y, Chen M, Wang Y, Sun Q, Zhao R, Guo S, Sun J, Cui X
Journal of ethnopharmacology 2024 Feb 10;320:117424
Journal of ethnopharmacology 2024 Feb 10;320:117424
Insights into the inhibition of stomach cancer MKN45 cell growth by Poria cocos ethanol-soluble extract based on MAPK/PI3K signaling pathways and components cell fishing.
Xie Z, Zeng H, He D, Luo J, Liu T, Shen B, Qin Y, Zhang S, Jin J
Journal of ethnopharmacology 2024 Feb 10;320:117417
Journal of ethnopharmacology 2024 Feb 10;320:117417
AR/RKIP pathway mediates the inhibitory effects of icariin on renal fibrosis and endothelial-to-mesenchymal transition in type 2 diabetic nephropathy.
Yao W, Tao R, Xu Y, Chen ZS, Ding X, Wan L
Journal of ethnopharmacology 2024 Feb 10;320:117414
Journal of ethnopharmacology 2024 Feb 10;320:117414
Huangqi Jiuni decoction prevents acute kidney injury induced by severe burns by inhibiting activation of the TNF/NF-κB pathway.
Hu W, Zhao J, Hu Y, Song S, Chen X, Sun Y
Journal of ethnopharmacology 2024 Feb 10;320:117344
Journal of ethnopharmacology 2024 Feb 10;320:117344
Counteracting Age-Related Netrin-1 Signaling Insufficiency Ameliorates Endothelial Cell Senescence and Angiogenesis Impairment.
Yang Z, Li H, Yan D, Luo P, Guan Y, Luo M, Nie H, Huang Y, Zhang L, Ruan L, Yan J, Zhang C
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Feb 1;79(2)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Feb 1;79(2)
DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
Liu C, Xu J, Fan J, Liu C, Xie W, Kong H
Experimental cell research 2024 Feb 1;435(1):113909
Experimental cell research 2024 Feb 1;435(1):113909
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Zhao L, Miao H, Quan M, Wang S, Zhang Y, Zhou H, Zhang X, Lin Z, Piao J
Chemico-biological interactions 2024 Feb 1;389:110866
Chemico-biological interactions 2024 Feb 1;389:110866
Systematic pan-cancer analysis of RNF186 with potential implications in progression and prognosis in human cancer.
Hu Y, Jiang N, Wang X, Wu X, Bo J, Chen Y, Zeng Y, Wei X, Zhang H, Li M
Life sciences 2024 Feb 1;338:122389
Life sciences 2024 Feb 1;338:122389
A study on the role of Taxifolin in inducing apoptosis of pancreatic cancer cells: screening results using weighted gene co-expression network analysis.
Chen SJ, Ren LK, Fei XB, Liu P, Wang X, Zhu CH, Pan YZ
Aging 2024 Feb 1;16(3):2617-2637
Aging 2024 Feb 1;16(3):2617-2637
Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130a-3p/long-chain acyl-CoA synthetase 1 axis.
Jiang Y, Ma F, Wang J, Chen X, Xue L, Chen X, Hu J
Non-coding RNA research 2024 Dec;9(4):1120-1132
Non-coding RNA research 2024 Dec;9(4):1120-1132
Different effects of low- and high-density lipoproteins in egg yolk on lipid metabolism of mouse: Role of phospholipids-to-cholesterol intake ratio.
Zhang F, Ma Y, Zhu H, Li J, Gu L, Chang C, Su Y, Yang Y
Journal of food science 2024 Dec;89(12):9751-9765
Journal of food science 2024 Dec;89(12):9751-9765
5-oxoETE promote thrombosis in antiphospholipid syndrome by triggering NETs formation through PLC/PKC/ERK pathway.
Song X, Chen X, Wang D, Bai J
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Dec;73(12):2165-2177
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Dec;73(12):2165-2177
ROR2 promotes cell cycle progression and cell proliferation through the PI3K/AKT signaling pathway in gastric cancer.
Liu Q, Zhao X, Shao X, Cheng P, Cui J, Han S
Molecular carcinogenesis 2024 Dec;63(12):2316-2331
Molecular carcinogenesis 2024 Dec;63(12):2316-2331
Circ-RNF111 Promotes Proliferation of Ovarian Cancer Cell SKOV-3 by Targeting the MiR-556-5p/CCND1 Axis.
Zuo L, Tan Y, Xu QL, Li XL, Xiao M
Biochemical genetics 2024 Dec;62(6):4884-4895
Biochemical genetics 2024 Dec;62(6):4884-4895
Metformin Protects Against Acute Kidney Injury Induced by Lipopolysaccharide via Up-Regulating the MCPIP1/SIRT1 Pathway.
Zhang WL, Zhang LJ, Liang P, Fang HL, Wang XL, Liu YJ, Deng HF
Biochemical genetics 2024 Dec;62(6):4591-4602
Biochemical genetics 2024 Dec;62(6):4591-4602
Shenqi Fuzheng injection restores the sensitivity to gefitinib in non-small cell lung cancer by inhibiting the IL-22/STAT3/AKT pathway.
Wang J, He X, Jia Z, Yan A, Xiao K, Liu S, Hou M, Long Y, Ding X
Pharmaceutical biology 2024 Dec;62(1):33-41
Pharmaceutical biology 2024 Dec;62(1):33-41
Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents.
Guo Y, Chen B, Guo J, Jiang P, Wang J, Sun W
Pharmaceutical biology 2024 Dec;62(1):233-249
Pharmaceutical biology 2024 Dec;62(1):233-249
Cai's herbal tea enhances mitochondrial autophagy of type 1 diabetic mellitus β cells through the AMPK/mTOR pathway and alleviates inflammatory response.
Li H, Gao Y, Li M, Dong Y, Chen J, Zhang B, Li K, Cai Y
Acta diabetologica 2024 Dec;61(12):1553-1567
Acta diabetologica 2024 Dec;61(12):1553-1567
Runx2 Suppresses Astrocyte Activation and Astroglial Scar Formation After Spinal Cord Injury in Mice.
Lu L, Ye J, Yi D, Qi T, Luo T, Wu S, Yang L, Li L, Zhang H, Chen D
Molecular neurobiology 2024 Dec;61(12):10820-10829
Molecular neurobiology 2024 Dec;61(12):10820-10829
Neuroprotective Effect of a Multistrain Probiotic Mixture in SOD1(G93A) Mice by Reducing SOD1 Aggregation and Targeting the Microbiota-Gut-Brain Axis.
Xin Z, Xin C, Huo J, Liu Q, Dong H, Li R, Liu Y
Molecular neurobiology 2024 Dec;61(12):10051-10071
Molecular neurobiology 2024 Dec;61(12):10051-10071
Long non-coding RNA SUN2-AS1 acts as a negative regulator of ISGs transcription to promote flavivirus infection.
Yang C, Chen W, Huang Y
Virology 2024 Dec;600:110245
Virology 2024 Dec;600:110245
Pseudorabies virus UL13 primes inflammatory response through downregulating heat shock factor 1.
Zhang WJ, Feng H, Zhang MM, Liu JS, Li LT, Chen HC, Liu ZF
Virology 2024 Dec;600:110214
Virology 2024 Dec;600:110214
Mechanism of Resveratrol on LPS/ATP-induced pyroptosis and inflammatory response in HT29 cells.
Zhao P, Ning J, Huang J, Huang X
Autoimmunity 2024 Dec;57(1):2427094
Autoimmunity 2024 Dec;57(1):2427094
Effects of MMP2 and its inhibitor TIMP2 on DNA damage, apoptosis and senescence of human lens epithelial cells induced by oxidative stress.
Deng X, Zhang Y, He X, Li L, Yue Z, Liang Y, Huang Y
Journal of bioenergetics and biomembranes 2024 Dec;56(6):619-630
Journal of bioenergetics and biomembranes 2024 Dec;56(6):619-630
Analysis and identification of ferroptosis-related diagnostic markers in rheumatoid arthritis.
Cai Y, Deng L, Yao J
Annals of medicine 2024 Dec;56(1):2397572
Annals of medicine 2024 Dec;56(1):2397572
Exploring the roles and therapeutic implications of melatonin-mediated KLF6 in the development of intracranial aneurysm.
Liu Y, Su Y, Chen L, Li A, Ma Z
Annals of medicine 2024 Dec;56(1):2397568
Annals of medicine 2024 Dec;56(1):2397568
M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling.
Wang Y, Geng X, Guo Z, Chu D, Liu R, Cheng B, Cui H, Li C, Li J, Li Z
Annals of medicine 2024 Dec;56(1):2313680
Annals of medicine 2024 Dec;56(1):2313680
Bleomycin induces endothelial cell pyroptosis and regulates fibrosis by activating the NLRP3/caspase-1/GSDMD pathway: a possible mechanism contributing to the sclerotherapy of venous malformations.
Chen S, Wang Y, Gao Q, Cui J, Shen W
Journal of molecular histology 2024 Dec;55(6):1239-1250
Journal of molecular histology 2024 Dec;55(6):1239-1250
Insulin-Like Growth Factor-Binding Protein 5 Promotes the Cell Proliferation and Osteogenic Potential of Dental Pulp Stem Cells Dependent on Its Nuclear Localisation Sequence.
Sun Z, Li J, Liu H, Fan Z
Journal of oral rehabilitation 2024 Dec;51(12):2664-2674
Journal of oral rehabilitation 2024 Dec;51(12):2664-2674
Bisphenol A disrupts the neuronal F-actin cytoskeleton by activating the RhoA/ROCK/LIMK pathway in Neuro-2a cells.
Guo Y, Wang Y, Li Q, Liu Q, Zhang X, Ren J, Wang C
Toxicology 2024 Dec;509:153994
Toxicology 2024 Dec;509:153994
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Wang L, Gui J, Tian B, Ding R, Wang W, Jiang C, Zhang S, Zhang X, Liu J, Jiang L
Toxicology 2024 Dec;509:153979
Toxicology 2024 Dec;509:153979
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
Zhang J, Wang T, Zhang H, Li N, Liu B, Fang L
Toxicology and applied pharmacology 2024 Dec;493:117148
Toxicology and applied pharmacology 2024 Dec;493:117148
Protein arginine methyltransferase 5 confers the resistance of triple-negative breast cancer to nanoparticle albumin-bound paclitaxel by enhancing autophagy through the dimethylation of ULK1.
Kong J, Dong Y, Li M, Fan J, Wang T
Toxicology and applied pharmacology 2024 Dec;493:117145
Toxicology and applied pharmacology 2024 Dec;493:117145
Hyperactivation of p53 contributes to mitotic catastrophe in podocytes through regulation of the Wee1/CDK1/cyclin B1 axis.
Feng J, Xie L, Lu W, Yu X, Dong H, Ma Y, Kong R
Renal failure 2024 Dec;46(2):2365408
Renal failure 2024 Dec;46(2):2365408
Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy.
Yan Q, Zhao Z, Liu D, Li J, Pan S, Duan J, Liu Z
Renal failure 2024 Dec;46(1):2337288
Renal failure 2024 Dec;46(1):2337288
Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial-mesenchymal transition.
Zhao J, Wang X, Wu Y, Zhao C
Renal failure 2024 Dec;46(1):2316259
Renal failure 2024 Dec;46(1):2316259
Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway.
Shao X, Li C, Liang J, Changzhong L
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2321651
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2321651
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes.
Xu M, Chen ZY, Li Y, Li Y, Guo G, Dai RZ, Ni N, Tao J, Wang HY, Chen QL, Wang H, Zhou H, Yang YN, Chen S, Chen L
The EMBO journal 2024 Dec;43(24):6383-6409
The EMBO journal 2024 Dec;43(24):6383-6409
Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect.
Yang Q, Liu G, Chen G, Chen G, Chen K, Fan L, Tu Y, Chen J, Shi Z, Chen C, Liu S, Deng G, Deng X, Sun C, Li X, Yang S, Zheng S, Chen B
Bioactive materials 2024 Dec;42:85-111
Bioactive materials 2024 Dec;42:85-111
Vascular wall microenvironment: Endothelial cells original exosomes mediated melatonin-suppressed vascular calcification and vascular ageing in a m6A methylation dependent manner.
Shan SK, Lin X, Wu F, Li CC, Guo B, Li FX, Zheng MH, Wang Y, Xu QS, Lei LM, Tang KX, Wu YY, Duan JY, Cao YC, Wu YL, Tan CM, Liu ZH, Zhou ZA, Liao XB, Xu F, Yuan LQ
Bioactive materials 2024 Dec;42:52-67
Bioactive materials 2024 Dec;42:52-67
MiR-19b-3p inhibits cell viability and proliferation and promotes apoptosis by targeting IGF1 in KGN cells.
Li Y, Ye Y, Zhang H, Yang Y, Zhang N, Gao H, Wu R
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2024 Dec;40(1):2425318
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2024 Dec;40(1):2425318
MST1R Gene Variants Predispose Individuals to Tetralogy of Fallot.
Feng Z, Huang X, Gao Y, Gao H, Na W, Tan C, Min S, Lu Y, Zhuang Q, Lin S, Ma X, Chen W, Yan W, Sheng W, Huang G
Phenomics (Cham, Switzerland) 2024 Dec;4(6):548-561
Phenomics (Cham, Switzerland) 2024 Dec;4(6):548-561
Mediation of circ_0007142 on miR-128-3p/S100A14 pathway to stimulate the progression of cervical cancer.
Feng Q, Shen Z, Wang F, Shi C
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9919-9933
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9919-9933
Epigenetic Regulation of RNF135 by LSD1 Promotes Stemness Maintenance and Brain Metastasis in Lung Adenocarcinoma.
Qu X, Ding T, Zhao H, Wang L
Environmental toxicology 2024 Dec;39(12):5321-5333
Environmental toxicology 2024 Dec;39(12):5321-5333
Increased UBD Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Wu T, Du M, Zeng L, Wang H, Li X
Environmental toxicology 2024 Dec;39(12):5250-5263
Environmental toxicology 2024 Dec;39(12):5250-5263
Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o-methoxy phenyl group as potential agents against gastric cancer.
Gan X, Wu Y, Zhu M, Liu B, Kong M, Xi Z, Li K, Wang H, Su T, Yao J, Khushafah F, Yi B, Wang J, Li W, Wu J
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2314233
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2314233
Genetic deletion of the apoptosis associated speck like protein containing a card in LysM(+) macrophages attenuates spinal cord injury by regulating M1/M2 polarization through ASC-dependent inflammasome signaling axis.
Ding SQ, Yan HZ, Gao JX, Chen YQ, Zhang N, Wang R, Li JY, Hu JG, Lü HZ
Experimental neurology 2024 Dec;382:114982
Experimental neurology 2024 Dec;382:114982
Esculin Alleviates Osteoarthritis Progression Through the Sirt1/NF-κB Pathway.
Sun T, Bai B, Wu H, Xing H, Li J
Phytotherapy research : PTR 2024 Dec;38(12):5793-5805
Phytotherapy research : PTR 2024 Dec;38(12):5793-5805
Engineering of phosphatidylserine-targeting ROS-responsive polymeric prodrug for the repair of ischemia-reperfusion-induced acute kidney injury.
Wang JH, Mao HB, Hu JB, Cheng S, Su H
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:1100-1114
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:1100-1114
NIR-Actuated Ferroptosis Nanomotor for Enhanced Tumor Penetration and Therapy.
Hu Z, Tan H, Ye Y, Xu W, Gao J, Liu L, Zhang L, Jiang J, Tian H, Peng F, Tu Y
Advanced materials (Deerfield Beach, Fla.) 2024 Dec;36(49):e2412227
Advanced materials (Deerfield Beach, Fla.) 2024 Dec;36(49):e2412227
A cisplatin and disulphiram co-loaded inclusion complex overcomes drug resistance by inhibiting cancer cell stemness in non-small cell lung cancer.
Ye W, Lv H, Zhang Q, Zhao J, Zhao X, Zhao G, Yan C, Sun F, Zhao Z, Jia X
Journal of drug targeting 2024 Dec;32(2):159-171
Journal of drug targeting 2024 Dec;32(2):159-171
H(2)Se-evolving bio-heterojunctions promote cutaneous regeneration in infected wounds by inhibiting excessive cellular senescence.
Yang F, Shu R, Dai W, Li B, Liu C, Yang H, Johnson HM, Yu S, Bai D, Yang W, Deng Y
Biomaterials 2024 Dec;311:122659
Biomaterials 2024 Dec;311:122659
Spatiotemporal release of non-nucleotide STING agonist and AKT inhibitor from implantable 3D-printed scaffold for amplified cancer immunotherapy.
Wang H, Liu Z, Fang Y, Luo X, Zheng C, Xu Y, Zhou X, Yuan Q, Lv S, Ma L, Lao YH, Tao Y, Li M
Biomaterials 2024 Dec;311:122645
Biomaterials 2024 Dec;311:122645
VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Lange SM, McFarland MR, Lamoliatte F, Carroll T, Krshnan L, Pérez-Ràfols A, Kwasna D, Shen L, Wallace I, Cole I, Armstrong LA, Knebel A, Johnson C, De Cesare V, Kulathu Y
Nature structural & molecular biology 2024 Dec;31(12):1872-1887
Nature structural & molecular biology 2024 Dec;31(12):1872-1887
Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats.
Fang Y, Zheng Y, Gao Q, Pang M, Wu Y, Feng X, Tao X, Hu Y, Lin Z, Lin W
Redox report : communications in free radical research 2024 Dec;29(1):2394714
Redox report : communications in free radical research 2024 Dec;29(1):2394714
Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway.
Hu R, Wu F, Zheng YQ
Redox report : communications in free radical research 2024 Dec;29(1):2332038
Redox report : communications in free radical research 2024 Dec;29(1):2332038
Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus.
Cai S, Ding R, Zhang H, Chen Q, Yu F, Xia Y, Chen Q, Miao X, Zhou B, Chen J, Liao L, Cheng X, Fu X
Materials today. Bio 2024 Dec;29:101323
Materials today. Bio 2024 Dec;29:101323
Biodegradable exosome-engineered hydrogels for the prevention of peritoneal adhesions via anti-oxidation and anti-inflammation.
Wang W, Ren Y, Yu Q, Jiang L, Yu C, Yue Z, Wang Y, Lu J, Che P, Li J, Sun H
Materials today. Bio 2024 Dec;29:101312
Materials today. Bio 2024 Dec;29:101312
Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation.
Du Y, Liu T, Ding T, Zeng X, Chen Q, Zhao H
Materials today. Bio 2024 Dec;29:101305
Materials today. Bio 2024 Dec;29:101305
Targeted regulation of autophagy using sorafenib-loaded biomineralization nanoenzyme for enhanced photodynamic therapy of hepatoma.
Lu T, Liu Z, Qian R, Zhou Y, Li J, Zhang Q, Yang H, Lu W, Xin Y, Xie Z, Yan L, Wang S, Qi R, Zhang Z
Materials today. Bio 2024 Dec;29:101270
Materials today. Bio 2024 Dec;29:101270
Injectable decellularized Wharton's jelly hydrogel containing CD56(+) umbilical cord mesenchymal stem cell-derived exosomes for meniscus tear healing and cartilage protection.
Kang S, Shi X, Chen Y, Zhang L, Liu Q, Lin Z, Lu H, Pan H
Materials today. Bio 2024 Dec;29:101258
Materials today. Bio 2024 Dec;29:101258
NR1D1 activation alleviates inflammatory response through inhibition of IL-6 expression in bovine endometrial epithelial cells.
Yang W, Jin M, Wang Y, Zhao H, Wang X, Guo Y, Li C, Xiao B, Zhang H, Kiran F, Wang A, Chao HW, Jin Y, Chen H
International journal of biological macromolecules 2024 Dec;283(Pt 4):137642
International journal of biological macromolecules 2024 Dec;283(Pt 4):137642
Structure elucidation and molecular mechanism of an immunomodulatory polysaccharide from Nostoc commune.
Yang Y, Ren P, Sun Y, Li J, Zhou X, Zhang H, He C, Dai H, Guan L
International journal of biological macromolecules 2024 Dec;283(Pt 1):137435
International journal of biological macromolecules 2024 Dec;283(Pt 1):137435
DNA ligase III mediates deoxynivalenol exposure-induced DNA damage in intestinal epithelial cells by regulating oxidative stress and interaction with PCNA.
Zhu X, Wu J, Chen X, Shi D, Hui P, Wang H, Wu Z, Wu S, Bao W, Fan H
International journal of biological macromolecules 2024 Dec;282(Pt 5):137137
International journal of biological macromolecules 2024 Dec;282(Pt 5):137137
Porcine reproductive and respiratory syndrome virus activates lipid synthesis through a ROS-dependent AKT/PCK1/INSIG/SREBPs axis.
Ma YX, Han YQ, Wang PZ, Wang MY, Yang GY, Li JL, Wang J, Chu BB
International journal of biological macromolecules 2024 Dec;282(Pt 1):136720
International journal of biological macromolecules 2024 Dec;282(Pt 1):136720
Aryl Hydrocarbon Receptor Alleviates Hepatic Fibrosis by Inducing Hepatic Stellate Cell Ferroptosis.
Liu S
Journal of cellular and molecular medicine 2024 Dec;28(23):e70278
Journal of cellular and molecular medicine 2024 Dec;28(23):e70278
Intestinal epithelial vitamin D receptor defense against inflammatory bowel disease via regulating microfold cells.
Sun X, Wu Y, Han C, Zhang N, Chen X, Chen Y
Immunology letters 2024 Dec;270:106925
Immunology letters 2024 Dec;270:106925
Single-cell m(6)A profiling in the mouse brain uncovers cell type-specific RNA methylomes and age-dependent differential methylation.
Tegowski M, Prater AK, Holley CL, Meyer KD
Nature neuroscience 2024 Dec;27(12):2512-2520
Nature neuroscience 2024 Dec;27(12):2512-2520
Regulation of LAMTOR1 by oxidative stress in retinal pigment epithelium: Implications for age-related macular degeneration pathogenesis.
Cai J, Liao F, Mao Y, Liu S, Wu X, Tang S, Wang S, Shan G, Wu S
Experimental eye research 2024 Dec;249:110129
Experimental eye research 2024 Dec;249:110129
Critical role of apoptosis in MeCP2-mediated epithelial-mesenchymal transition of ARPE-19 cells.
Zhang Y, Wu F, Guo S, Yin R, Yuan M, Li X, Zhao X, Li X
Journal of cellular physiology 2024 Dec;239(12):e31429
Journal of cellular physiology 2024 Dec;239(12):e31429
A rapid and versatile reverse genetic approach and visualization animal models for emerging zoonotic pseudorabies virus.
Zhang Y, Li X, Zhang J, Duan Y, Chen P, Shi L, Yuan C, Cao L, Sun M, Wang Y, Kong X, Zheng H, Wang Q
Antiviral research 2024 Dec;232:106036
Antiviral research 2024 Dec;232:106036
Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-x(L), display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity.
Zhang X, Tao Y, Xu Z, Jiang B, Yang X, Huang T, Tan W
Biochemical pharmacology 2024 Dec;230(Pt 1):116542
Biochemical pharmacology 2024 Dec;230(Pt 1):116542
Comprehensive gene set enrichment and variation analyses identify SUV39H1 as a potential prognostic biomarker for glioblastoma immunorelevance.
Liu J, Luo Q, Zhao H, Yang M, Yang J, Wang Y, Zhao M, Mao J, Chen J, Guo B, Zhang L
Computational and structural biotechnology journal 2024 Dec;23:4161-4176
Computational and structural biotechnology journal 2024 Dec;23:4161-4176
Hydrogel and Microgel Collaboration for Spatiotemporal Delivery of Biofactors to Awaken Nucleus Pulposus-Derived Stem Cells for Endogenous Repair of Disc.
Wang J, Huang Y, Luan T, Shi P, Guo L, Zhang Q, Shi G, Hao Z, Chen T, Zhang L, Li J
Small (Weinheim an der Bergstrasse, Germany) 2024 Dec;20(49):e2404732
Small (Weinheim an der Bergstrasse, Germany) 2024 Dec;20(49):e2404732
The time-dependent expression of FPR2 and ANXA1 in murine deep vein thrombosis model and its relation to thrombus age.
Huang JJ, Zhuo JY, Wang Q, Sun Y, Qi JX, Wu JJ, Zhang Y, Chen G, Jiang PF, Fan YY
Forensic science, medicine, and pathology 2024 Dec;20(4):1155-1165
Forensic science, medicine, and pathology 2024 Dec;20(4):1155-1165
Role of GLCCI1 in inhibiting PI3K-induced NLRP3 inflammasome activation in asthma.
Zhang Y, Jiang Y, Zhang D, Hu X, Deng S, Li X, Feng J
Chinese medical journal pulmonary and critical care medicine 2024 Dec;2(4):279-288
Chinese medical journal pulmonary and critical care medicine 2024 Dec;2(4):279-288
Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway.
Shang P, Yang J, Shao L, Sun C, Ji J, Wang X, Zheng Z, Guo X
Pharmaceutical science advances 2024 Dec;2:100057
Pharmaceutical science advances 2024 Dec;2:100057
Activation of spleen tyrosine kinase (SYK) contributes to neuronal pyroptosis and cognitive impairment in diabetic mice via the NLRP3/Caspase-1/GSDMD signaling pathway.
Zhou C, Li J, Wu X, Liu F
Experimental gerontology 2024 Dec;198:112626
Experimental gerontology 2024 Dec;198:112626
Lithospermic acid inhibits dengue virus infection through binding with envelope proteins.
Zhong M, Wang X, Meng Y, Liao F, Li Z, Zheng W, Wang W, Dai W, Zhang S, Li G
Microbial pathogenesis 2024 Dec;197:107055
Microbial pathogenesis 2024 Dec;197:107055
Testosterone-Induced H3K27 Deacetylation Participates in Granulosa Cell Proliferation Suppression and Pathogenesis of Polycystic Ovary Syndrome.
Tong X, Hu Z, Zhou H, Zhang Y, Zhang YL, Zhang S, Jin J
The American journal of pathology 2024 Dec;194(12):2326-2340
The American journal of pathology 2024 Dec;194(12):2326-2340
ANRIL upregulates TGFBR1 to promote idiopathic pulmonary fibrosis in TGF-β1-treated lung fibroblasts via sequestering let-7d-5p.
Wu W, Yu N, Chen W, Zhu Y
Epigenetics 2024 Dec;19(1):2435682
Epigenetics 2024 Dec;19(1):2435682
An artificial peptide inhibits autophagy through calcineurin-TFEB pathway.
Yang Y, Li Y, Shang H, Liu Y, Li W, Chen L, Cheng N, Zhang Y, Zhang N, Yin Y, Tong L, Li Z, Yang J, Luo J
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119853
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119853
Long non-coding RNA Snhg15 promotes preosteoblast proliferation by interacting with and stabilizing nucleolin.
Zhu J, Mo L, Li M, Wang Y, Zhang G, Tao Z, Liao X, Du M, He H
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119847
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119847
TRPV4-β-catenin axis is a novel therapeutic target for dry skin-induced chronic itch.
Tang Y, Zhou Y, Ren J, Wang Y, Li X, Qi M, Yang Y, Zhu C, Wang C, Ma Y, Tang Z, Yu G
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167491
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167491
TMAO induces pyroptosis of vascular endothelial cells and atherosclerosis in ApoE(-/-) mice via MBOAT2-mediated endoplasmic reticulum stress.
Yu B, Yuan C, Chen J, Zhou Z, Zhang Y, Su M, Wei D, Wu P
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Dec;1869(8):159559
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Dec;1869(8):159559
Molecular mechanism through which Tripterygium hypoglaucum (Lévl.) Hutch alleviates psoriasis.
Sun Y, Wang J, Hu P, Tang Y, Wang Y, Ye J, Yang X, Yin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117647
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117647
Inhibition of JNK/STAT3/NF-KB pathway-mediated migration and clonal formation of lung adenocarcinoma A549 cells by daphnetin.
Lv Z, Du Y, Zhang H, Fang H, Guo Y, Zeng L, Chen Y, Li D, Li R
Cell adhesion & migration 2024 Dec;18(1):27-37
Cell adhesion & migration 2024 Dec;18(1):27-37
Knockdown of PIK3R6 impedes the onset and advancement of clear cell renal cell carcinoma.
Yang J, Zhong X, Gao X, Xie W, Chen Y, Liao Y, Zhang P
Cell adhesion & migration 2024 Dec;18(1):1-12
Cell adhesion & migration 2024 Dec;18(1):1-12
BMP5 promotes trophoblast functions upon N-glycosylation via the BMP5-SMAD1/5 signaling pathway in preeclampsia.
Wang H, Fan N, Cui X, Xie R, Tang Y, Thomas AM, Li S, Zhang JV, Liu S, Qin H
Placenta 2024 Dec;158:240-252
Placenta 2024 Dec;158:240-252
ARID1A recruits GATA2 to regulate the senescence of trophoblast cells under high-glucose condition.
Huang Y, Yang X, Wang Y, Nai Y, Ji L, Zhu H, Lai R, Wang QT, Hu H, Wang L
Placenta 2024 Dec;158:156-164
Placenta 2024 Dec;158:156-164
Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stress.
Li Y, Zhao L, Liu Z, Chen Y, Li X, Zhu D, Liu L
Bioorganic chemistry 2024 Dec;153:107982
Bioorganic chemistry 2024 Dec;153:107982
Discovery and optimization of novel 4-morpholinothieno[3,2-d]pyrimidine derivatives as potent BET inhibitors for cancer therapy.
Ran K, Li Y, Zhang YM, Tang DY, Chen ZZ, Xu ZG, Zhang L, Wang BC, Huang JH
Bioorganic chemistry 2024 Dec;153:107929
Bioorganic chemistry 2024 Dec;153:107929
Design, green synthesis, and anti-glutamate damage screening of chalcone derivatives with spiro-heterocyclic structures as potential anti-ischemic brain and eye damage agents.
Wu J, Huang C, Ren S, Wu T, Li Y, Zhong H, Su T, Chen Y, Tan X, Wu W, Wang J, Li W
Bioorganic chemistry 2024 Dec;153:107870
Bioorganic chemistry 2024 Dec;153:107870
Design, synthesis, and biological evaluation of novel HPK1 inhibitors possessing 3-cyano-quinoline moiety.
Chen L, Zhang B, Zhou P, Duan Y, He C, Zhong W, Wang T, Xu S, Chen J, Yao H, Xu J
Bioorganic chemistry 2024 Dec;153:107814
Bioorganic chemistry 2024 Dec;153:107814
Discovery of novel 5-phenyl-1H-pyrrole-2-carboxylic acids as Keap1-Nrf2 inhibitors for acute lung injury treatment.
Tang J, Tie X, Zhi S, Wang Z, Zhao Q, Qu Z, Lu G, Li Q, Wu Y, Shi Y
Bioorganic chemistry 2024 Dec;153:107741
Bioorganic chemistry 2024 Dec;153:107741
Altingia chinensis petroleum ether extract suppresses NSCLC via induction of apoptosis, attenuation of EMT, and downregulation of PI3K/Akt pathway.
Qin Y, Zhang D, Shangguan C, Xu C, Li S, Li Y, Liu Y, Jiang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156218
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156218
Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway.
Tian H, Pan Q, Wu J, Liao J, Wan Y, Pei K, Liu Q, Zeng L, Cao Y, Shi Q, Kuang N, Sun L, Yu X, Huang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156214
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156214
Yi-Fei-San-Jie Chinese medicine formula reverses immune escape by regulating deoxycholic acid metabolism to inhibit TGR5/STAT3/PD-L1 axis in lung cancer.
Chen Z, Rao X, Sun L, Qi X, Wang J, Wang S, An B, Lin J, Lin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156175
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156175
Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition.
Huang G, Xu J, Li Y, Song L, Wen C, Ruan Q, Wen Z, Qi J, Deng J, Liu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156103
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156103
Nrf2-dependent hepatoprotective effect of ellagic acid in titanium dioxide nanoparticles-induced liver injury.
Wang K, Hao Z, Xie J, Ma L, Zhang W, Mo J, Li L, Jin C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156064
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156064
Obacunone improves dihydrotestosterone-induced androgen alopecia by inhibiting androgen receptor dimerization.
Liu J, Chen S, Yan W, Liu J, Jin Q, Zhang Y, Zhang F, Pan Y, Hu W, Jin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156042
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156042
Single-cell RNA transcriptomics reveals Du-Zhong-Wan promotes osteoporotic fracture healing via YAP/β-catenin/VEGF axis in BMSCs.
Dong R, Wei J, Tian S, Wang J, Ma Y, Li Y, Liu RX, Liu YQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155572
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155572
Hepatic miR-363 promotes nonalcoholic fatty liver disease by suppressing INSIG1.
Wang L, Jia G, Fu R, Liang J, Xue W, Zheng J, Qin Y, Zhang M, Meng J
The Journal of nutritional biochemistry 2024 Dec;134:109717
The Journal of nutritional biochemistry 2024 Dec;134:109717
Tribbles pseudokinase 3 promotes enterovirus A71 infection via dual mechanisms.
Wang H, Li K, Cui B, Yan H, Wu S, Wang K, Yang G, Jiang J, Li Y
Emerging microbes & infections 2024 Dec;13(1):2307514
Emerging microbes & infections 2024 Dec;13(1):2307514
PYGB targeted by androgen receptor contributes to tumor progression and metabolic reprogramming in esophageal squamous carcinoma.
Miao H, Xu C, Gao W, Zhong L, Li H, Wen Z, Ren Q, Chen Y
Cellular signalling 2024 Dec;124:111481
Cellular signalling 2024 Dec;124:111481
GALNT14-mediated O-glycosylation drives lung adenocarcinoma progression by reducing endogenous reactive oxygen species generation.
Tang B, Wang K, Ren Q, Zhou J, Xu Y, Liu L, Yin B, Zhang Y, Huang Q, Lv R, Luo Z, Zhao H, Shen L
Cellular signalling 2024 Dec;124:111477
Cellular signalling 2024 Dec;124:111477
Unraveling the biological functions of UCEC: Insights from a prognostic signature model.
Zhu Q, Shan W, Li X, Chen Y, Huang X, Xia B, Qian L
Computational biology and chemistry 2024 Dec;113:108219
Computational biology and chemistry 2024 Dec;113:108219
Discovery of Balasubramide Derivative with Tissue-Specific Anti-Inflammatory Activity Against Acute Lung Injury by Targeting VDAC1.
Song JQ, Shen LJ, Wang HJ, Liu QB, Ye LB, Liu K, Shi L, Cai B, Lin HS, Pang T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2410550
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2410550
The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR-99a/mTOR-Mediated Autophagy and Apoptosis.
Hu HF, Fu JY, Han L, Gao GB, Zhang WX, Yu SM, Li N, Li YJ, Lu YF, Ding XF, Pan YL, Wang Y, He QY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2409498
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2409498
Transcriptomics-Based Liquid Biopsy for Early Detection of Recurrence in Locally Advanced Gastric Cancer.
Ding P, Wu J, Wu H, Li T, Niu X, Yang P, Guo H, Tian Y, He J, Yang J, Gu R, Zhang L, Meng N, Li X, Guo Z, Meng L, Zhao Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406276
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406276
Selenium nanoparticles affect chicken offspring's intestinal health better than other selenium sources.
Chen Y, Zhang S, Gao X, Hao Z, Guo Y, Wang Y, Yuan J
Poultry science 2024 Dec;103(12):104367
Poultry science 2024 Dec;103(12):104367
Up-regulated Lnc BTU promotes the production of duck plague virus DNA polymerase and inhibits the activation of JAK-STAT pathway to facilitate duck plague virus replication.
Luo N, Cheng A, Wang M, Chen S, Liu M, Zhu D, Wu Y, Tian B, Ou X, Huang J, Wu Z, Yin Z, Jia R
Poultry science 2024 Dec;103(12):104238
Poultry science 2024 Dec;103(12):104238
Conditional ablation of MCU exacerbated cardiac pathology in a genetic arrhythmic model of CPVT.
Deb A, Tow BD, Hao J, Nguyen BL, Gomez V, Stewart JA Jr, Smuder AJ, Knollmann BC, Wang Y, Liu B
Journal of molecular and cellular cardiology plus 2024 Dec;10
Journal of molecular and cellular cardiology plus 2024 Dec;10
Isoechinulin B, a natural product from Antarctic fungus, attenuates acute liver injury by inhibiting excessive cell adhesion.
Sun H, Pang X, Li JR, Li H, Tang M, Zhang T, Yu LY, Peng ZG
European journal of pharmacology 2024 Dec 5;984:177065
European journal of pharmacology 2024 Dec 5;984:177065
RTA408 alleviates lipopolysaccharide-induced acute lung injury via inhibiting Bach1-mediated ferroptosis.
Wu Y, Zhang Y, Ge L, He S, Zhang Y, Chen D, Nie Y, Zhu M, Pang Q
International immunopharmacology 2024 Dec 5;142(Pt B):113250
International immunopharmacology 2024 Dec 5;142(Pt B):113250
Simvastatin induces ferroptosis and activates anti-tumor immunity to sensitize anti-PD-1 immunotherapy in microsatellite stable gastric cancer.
Ning Y, Fang S, Zhang R, Fang J, Lin K, Ding Y, Nie H, Zhou J, Zhao Q, Ke H, Wang H, Wang F
International immunopharmacology 2024 Dec 5;142(Pt B):113244
International immunopharmacology 2024 Dec 5;142(Pt B):113244
CD39 inhibitor (POM-1) enhances radiosensitivity of esophageal squamous cell carcinoma (ESCC) cells by promoting apoptosis through the Bax/Bcl-2/Caspase 9/Caspase 3 pathway.
Wang Y, Zhang R, Huang X, He X, Geng S, Pan S, Guo W, Liu X, Dang Y, Qu J, Ma H, Zhao X
International immunopharmacology 2024 Dec 5;142(Pt B):113242
International immunopharmacology 2024 Dec 5;142(Pt B):113242
Melatonin prevents glyphosate-induced hepatic lipid accumulation in roosters via activating Nrf2 pathway.
Zhang SH, Zhang HJ, Jia YZ, Wang ZY, You ZH, Lian CY, Wang L
International immunopharmacology 2024 Dec 5;142(Pt B):113180
International immunopharmacology 2024 Dec 5;142(Pt B):113180
Interleukin(IL)-37 attenuates isoproterenol (ISO)-induced cardiac hypertrophy by suppressing JAK2/STAT3-signaling associated inflammation and oxidative stress.
Guo X, Wang P, Wei H, Yan J, Zhang D, Qian Y, Guo B
International immunopharmacology 2024 Dec 5;142(Pt B):113134
International immunopharmacology 2024 Dec 5;142(Pt B):113134
Nuciferine ameliorates osteoarthritis: An in vitro and in vivo study.
Peng M, Shen G, Tu Q, Zhang W, Wang J
International immunopharmacology 2024 Dec 5;142(Pt B):113098
International immunopharmacology 2024 Dec 5;142(Pt B):113098
Identification of a nomogram predicting overall survival based on ADAP2-related apoptosis genes in gliomas.
Zhang C, Wang J, Niu Z, Zhang K, Wang C, Wang S, Hou S, Yu D, Lin N
International immunopharmacology 2024 Dec 5;142(Pt A):113084
International immunopharmacology 2024 Dec 5;142(Pt A):113084
MNSFβ promotes LPS-induced TNFα expression by increasing the localization of RC3H1 to stress granules, and the interfering peptide HEPN2 reduces TNFα production by disrupting the MNSFβ-RC3H1 interaction in macrophages.
Jiang HY, Gu WW, Gan J, Yang Q, Shi Y, Lian WB, Xu HR, Yang SH, Yang L, Zhang X, Wang J
International immunopharmacology 2024 Dec 5;142(Pt A):113053
International immunopharmacology 2024 Dec 5;142(Pt A):113053
A synergistic effect of triptolide and curcumin on rheumatoid arthritis by improving cell proliferation and inducing cell apoptosis via inhibition of the IL-17/NF-κB signaling pathway.
Zhang C, Weng Y, Wang H, Zhan S, Li C, Zheng D, Lin Q
International immunopharmacology 2024 Dec 5;142(Pt A):112953
International immunopharmacology 2024 Dec 5;142(Pt A):112953
RNA Binding of GAPDH Controls Transcript Stability and Protein Translation in Acute Myeloid Leukemia.
Shamloo S, Schloßhauer JL, Tiwari S, Fischer KD, Ghebrechristos Y, Kratzenberg L, Bejoy AM, Aifantis I, Wang E, Imig J
bioRxiv : the preprint server for biology 2024 Dec 5;
bioRxiv : the preprint server for biology 2024 Dec 5;
Single-cell RNA sequencing analysis reveals potential key prognostic markers in hepatocellular carcinoma.
Cui H, Yang W
Discover oncology 2024 Dec 4;15(1):747
Discover oncology 2024 Dec 4;15(1):747
Milk fat globule-epidermal growth factor 8 exerts anti-osteoarthritis effects by inhibiting apoptosis and inducing autophagy in mouse chondrocytes.
Gao Y, Feng J, Chen Q, Wang Z, Yang Z
Biochemical and biophysical research communications 2024 Dec 31;741:151022
Biochemical and biophysical research communications 2024 Dec 31;741:151022
Omentin-1 ameliorates pulmonary arterial hypertension by inhibiting endoplasmic reticulum stress through AMPKα signaling.
Deng X, Luo H, He J, Deng W, Wang D
Clinical and experimental hypertension (New York, N.Y. : 1993) 2024 Dec 31;46(1):2332695
Clinical and experimental hypertension (New York, N.Y. : 1993) 2024 Dec 31;46(1):2332695
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial-mesenchymal transition.
Chen D, Jiang J, Zhang W, Li X, Ge Q, Liu X, Li X
Cancer biology & therapy 2024 Dec 31;25(1):2427410
Cancer biology & therapy 2024 Dec 31;25(1):2427410
DNAJB4/HLJ1 deficiency sensitizes diethylnitrosamine-induced hepatocarcinogenesis with peritumoral STAT3 activation.
Luo WJ, Hsu WL, Lu CY, Chien MH, Chang JH, Su KY
Cell biology and toxicology 2024 Dec 30;41(1):20
Cell biology and toxicology 2024 Dec 30;41(1):20
SPDEF ameliorates UUO-induced renal fibrosis by transcriptional activation of NR4A1.
Wang H, Wei Z, Xu C, Fang F, Wang Z, Zhong Y, Wang X
Molecular medicine (Cambridge, Mass.) 2024 Dec 30;30(1):282
Molecular medicine (Cambridge, Mass.) 2024 Dec 30;30(1):282
Transcriptional landscape and predictive potential of long noncoding RNAs in peritoneal recurrence of gastric cancer.
Cai XX, Chen GM, Zheng ZQ, Yin YX, Wang S, Qiao L, Chen XJ, Zhao BW, Duan JL, Liang CC, Zhang RP, Wei CZ, Zhang FY, Huang BW, Liu ZX, Zhou ZW, Xie D, Cai MY, Yuan SQ, Li YF, Nie RC
Molecular cancer 2024 Dec 30;23(1):284
Molecular cancer 2024 Dec 30;23(1):284
HMGCS2 and AMACR as potential targets linking mitochondrial dysfunction and ulcerative colitis.
Zhu R, Bai X, Li Z, Liang H, Song H, Chen L, Miao Y, Zhang F, Niu J
Scientific reports 2024 Dec 30;14(1):31783
Scientific reports 2024 Dec 30;14(1):31783
Bone marrow mesenchymal stem cells modulate miR-202-3p to suppress neuronal apoptosis following spinal cord injury through autophagy activation via the AMPK, MAPK, and PI3K/AKT/mTOR signaling pathway.
Huang K, Fang J, Sun W, Zeng Y, Shi B, Ren B, Bi H, Shuai L
Scientific reports 2024 Dec 3;14(1):30099
Scientific reports 2024 Dec 3;14(1):30099
Identifying novel aging-related diagnostic and prognostic models and aging-targeted drugs for sepsis patients.
Yang K, Lu Y, Gu J, Nie Y, Zhang T
Scientific reports 2024 Dec 28;14(1):31445
Scientific reports 2024 Dec 28;14(1):31445
Intervention effect of regulating GABA-A receptor activity on the formation of experimental abdominal aortic aneurysm in rats.
Zhu JX, Zhou C, Huang LZ, Guo JW, Yin NP, Yang F, Zhang YD, Yang Y
Scientific reports 2024 Dec 28;14(1):31388
Scientific reports 2024 Dec 28;14(1):31388
N7-methyladenosine-induced SLC7A7 serves as a prognostic biomarker in pan-cancer and promotes CRC progression in colorectal cancer.
Wang F, Zhang S, Chen Z, Gu X, Zhang G, Zhang H, Yuan W
Scientific reports 2024 Dec 28;14(1):30755
Scientific reports 2024 Dec 28;14(1):30755
Discovery of SILA-123 as a Highly Potent FLT3 Inhibitor for the Treatment of Acute Myeloid Leukemia with Various FLT3 Mutations.
Wei TH, Wang ZX, Lu MY, Xu YJ, Yang J, Ni XF, Cheng Y, Zhang MY, Liu JC, Li QQ, Cai J, Chen ZJ, Kang JB, Li N, Dai WC, Ding N, Yu YC, Leng XJ, Xue X, Wang XL, Sun SL, Yang Y, Li NG, Shi ZH
Journal of medicinal chemistry 2024 Dec 26;67(24):21752-21780
Journal of medicinal chemistry 2024 Dec 26;67(24):21752-21780
USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc.
Li Y, Wang W, Sun L, Huang J, Ma X, Li S, Shi X
Journal of molecular histology 2024 Dec 26;56(1):54
Journal of molecular histology 2024 Dec 26;56(1):54
GANT61 surmounts drug resistance of ADR by upregulating lysosome activities and reducing BCL2 expression in HL-60/ADR cells.
Zhou C, Zhao L, Zhou M, Wu C, Liu G, Long J, Shi Y, Liu C
Cancer cell international 2024 Dec 26;24(1):430
Cancer cell international 2024 Dec 26;24(1):430
The Pathogenic Role of Expanded CD8⁺CD28(null) Angiogenic T Cells in ANCA-Associated Vasculitis.
Shen H, Miao J, Sun H, Zhang K, Liu R, Li Z, Zhang L, Zhang P, Wang J, Zhang B, Chen L, Zheng Z, Zhu P
Biomedicines 2024 Dec 26;13(1)
Biomedicines 2024 Dec 26;13(1)
Notoginsenoside R1-Protocatechuic aldehyde reduces vascular inflammation and calcification through increasing the release of nitric oxide to inhibit TGFβR1-YAP/TAZ pathway in vascular smooth muscle cells.
Cui X, Zhang L, Lin L, Hu Y, Zhang M, Sun B, Zhang Z, Lu M, Guan X, Hao J, Li Y, Li C
International immunopharmacology 2024 Dec 25;143(Pt 3):113574
International immunopharmacology 2024 Dec 25;143(Pt 3):113574
Acetyl-11-keto-β-boswellia acid attenuates Ti particle-induced osteoblastic oxidative stress and osteolysis through the Foxo3 signaling pathway.
Gu Y, Wu Z, Xie H, Qian Z, Li Z, Tang Y, Wang Q, Fang T, Tao H, Chen K, Zhu P, Ding Y, Xu Y, Peng Y, Ye H, Guo X, Tao Y, Gu Y
International immunopharmacology 2024 Dec 25;143(Pt 3):113547
International immunopharmacology 2024 Dec 25;143(Pt 3):113547
Nicotinamide adenine dinucleotide phosphate alleviates intestinal ischemia/reperfusion injury via Nrf2/HO-1 pathway.
Chen SY, Xu H, Qin Y, He TQ, Shi RR, Xing YR, Xu J, Cong RC, Wang MR, Yang JS, Gu JH, He BS
International immunopharmacology 2024 Dec 25;143(Pt 2):113478
International immunopharmacology 2024 Dec 25;143(Pt 2):113478
Comprehensive multi-omics analysis of the prognostic value and immune signature of NCF2 in pan-cancer and its relationship with acute myeloid leukemia.
Zhong F, Zeng Y, Yan Y, Guo L, Guo Q, Liu W, Liu C
International immunopharmacology 2024 Dec 25;143(Pt 1):113364
International immunopharmacology 2024 Dec 25;143(Pt 1):113364
Neutrophil extracellular traps induce barrier dysfunction in DSS-induced ulcerative colitis via the cGAS-STING pathway.
Sun T, Wang P, Zhai X, Wang Z, Miao X, Yang Y, Wu J
International immunopharmacology 2024 Dec 25;143(Pt 1):113358
International immunopharmacology 2024 Dec 25;143(Pt 1):113358
Amino acid metabolism-related genes as potential biomarkers and the role of MATN3 in stomach adenocarcinoma: A bioinformatics, mendelian randomization and experimental validation study.
Zhu W, Fu M, Li Q, Chen X, Liu Y, Li X, Luo N, Tang W, Zhang Q, Yang F, Chen Z, Zhang Y, Peng B, Zhang Q, Zhang Y, Peng X, Hu G
International immunopharmacology 2024 Dec 25;143(Pt 1):113253
International immunopharmacology 2024 Dec 25;143(Pt 1):113253
Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis.
Zhang X, Ling C, Xiong Z, Gong T, Luo S, Liu X, Zhang L, Liao C, Lu Y, Huang X, Zhou W, Zhou S, Liu Y, Tang J
Cell reports 2024 Dec 24;43(12):115060
Cell reports 2024 Dec 24;43(12):115060
Intersectin1 promotes clathrin-mediated endocytosis by organizing and stabilizing endocytic protein interaction networks.
Jin M, Iwamoto Y, Shirazinejad C, Drubin DG
Cell reports 2024 Dec 24;43(12):114989
Cell reports 2024 Dec 24;43(12):114989
Tak1 licenses mitochondrial transfer from astrocytes to POMC neurons to maintain glucose and cholesterol homeostasis.
Yin K, Zhang T, Lu X, Shen Q, Gu K, Huang Y, Li C, Hou J, Li J, Zhang G
Cell reports 2024 Dec 24;43(12):114983
Cell reports 2024 Dec 24;43(12):114983
Doublecortin regulates the mitochondrial-dependent apoptosis in glioma via Rho-A/Net-1/p38-MAPK signaling.
Nadeem I, Han Z, Xiaoliang H, Adzraku SY, Kambey PA, Kanwore K, Peipei M, Adekunle AO, Adu-Amankwaah J, Ayanlaja AA, Zheng Y, Dianshuai G, Liu X, Song Y
Molecular medicine (Cambridge, Mass.) 2024 Dec 24;30(1):272
Molecular medicine (Cambridge, Mass.) 2024 Dec 24;30(1):272
Rapamycin and Niacin combination induces apoptosis and cell cycle arrest through autophagy activation on acute myeloid leukemia cells.
Subay LB, Gencer Akçok EB, Akçok İ
Molecular biology reports 2024 Dec 23;52(1):75
Molecular biology reports 2024 Dec 23;52(1):75
A mucus layer derived from porcine intestinal organoid air-liquid interface monolayer attenuates swine enteric coronavirus infection by antiviral activity of Muc2.
Yang N, Li Y, Cai Y, Liu Y, Zhang Y, Fu Y, Tan C, Willems L, Liu G
BMC biology 2024 Dec 23;22(1):297
BMC biology 2024 Dec 23;22(1):297
Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction.
Li Z, LaPenna KB, Gehred ND, Yu X, Tang WHW, Doiron JE, Xia H, Chen J, Driver IH, Sachse FB, Muraoka N, Katsouda A, Zampas P, Haydel AG, Quiriarte H, Zagouras A, Wilcox J, Gromova T, Shah SJ, Goodchild TT, Allerton TD, Jensen MB, Papapetropoulos A, Sharp TE, Vondriska TM, Lefer DJ
bioRxiv : the preprint server for biology 2024 Dec 23;
bioRxiv : the preprint server for biology 2024 Dec 23;
ANXA1-FPR2 axis mitigates the susceptibility to atrial fibrillation in obesity via rescuing AMPK activity in response to lipid overload.
Liu P, Wang L, Wang Y, Jin L, Gong H, Fan J, Zhang Y, Li H, Fu B, Wang Q, Fu Y, Fan B, Li X, Wang H, Qin X, Zheng Q
Cardiovascular diabetology 2024 Dec 21;23(1):452
Cardiovascular diabetology 2024 Dec 21;23(1):452
Exosomes derived from hypoxic mesenchymal stem cells restore ovarian function by enhancing angiogenesis.
Qu Q, Liu L, Wang L, Cui Y, Liu C, Jing X, Xu X
Stem cell research & therapy 2024 Dec 21;15(1):496
Stem cell research & therapy 2024 Dec 21;15(1):496
Salivary adenoid cystic carcinoma-derived α2,6-sialylated extracellular vesicles increase vascular permeability by triggering ER-stress in endothelial cells and promote lung metastasis.
Dong Q, Dong M, Liu X, Zhou J, Wu S, Liu Z, Niu W, Liu T
Cancer letters 2024 Dec 20;611:217407
Cancer letters 2024 Dec 20;611:217407
JAG1 mediates apoptosis in herpes simplex keratitis by suppressing autophagy via ROS/JAG1/NOTCH1/pULK1 signaling pathway.
Chang J, Yao Y, Sun X, Wang W, Qian H, Liu Y, Xue C, Ye W, Jiang F
Cell biology and toxicology 2024 Dec 20;41(1):1
Cell biology and toxicology 2024 Dec 20;41(1):1
Zinc finger protein 593 promotes breast cancer development by ensuring DNA damage repair and cell-cycle progression.
Zhang Y, Tang X, Wang C, Wang M, Li M, Li X, Yao L, Xu Y
iScience 2024 Dec 20;27(12):111513
iScience 2024 Dec 20;27(12):111513
lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing.
Sun YM, Zhu SX, Chen XT, Pan Q, An Y, Chen TQ, Huang HJ, Pu KJ, Lian JY, Zhao WL, Wang WT, Chen YQ
Molecular cell 2024 Dec 19;84(24):4878-4895.e10
Molecular cell 2024 Dec 19;84(24):4878-4895.e10
KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus.
Zhao H, Lin Z, Zhang P, Rao J, Xu S, Luo Q, Li J
Arthritis research & therapy 2024 Dec 19;26(1):222
Arthritis research & therapy 2024 Dec 19;26(1):222
NCAM1 modulates the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary hypertension.
Chen Y, Liu N, Yang Y, Yang L, Li Y, Qiao Z, Zhang Y, Li A, Xiang R, Wen L, Huang W
Respiratory research 2024 Dec 19;25(1):435
Respiratory research 2024 Dec 19;25(1):435
17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson's disease.
Wang G, Zhuang W, Zhou Y, Wang X, Li Z, Liu C, Li W, He M, Lv E
Cell death discovery 2024 Dec 19;10(1):507
Cell death discovery 2024 Dec 19;10(1):507
Apigenin Reduces Lipid Droplet Accumulation in Hepatocytes by Enhancing Chaperone-Mediated Autophagy via AMPK.
Lu J, Zhou H, Hu J, Zhang R, Meng Z, Guan S
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27965-27977
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27965-27977
Bexarotene ameliorated the pulmonary inflammation and M1 polarization of alveolar macrophages induced by cigarette smoke via PPARγ/HO-1.
Feng H, Li Z, Zheng R
Respiratory research 2024 Dec 18;25(1):431
Respiratory research 2024 Dec 18;25(1):431
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
Gao M, Wang M, Zhou S, Hou J, He W, Shu Y, Wang X
Cancer cell international 2024 Dec 18;24(1):400
Cancer cell international 2024 Dec 18;24(1):400
miR-184, a downregulated ovary-elevated miRNA transcriptionally activated by SREBF2, exerts anti-apoptotic properties in ovarian granulosa cells through inducing SMAD3 expression.
Shan B, Huo Y, Guo Z, Li Q, Pan Z, Li Q, Du X
Cell death & disease 2024 Dec 18;15(12):892
Cell death & disease 2024 Dec 18;15(12):892
Network pharmacology and anticancer mechanism study of Dendrobium nobile dendrobine in the treatment of colorectal cancer.
Luo P, Huang C, Guo J, Yao X, Pan C, Bao A, Li F, Li YY
Discover oncology 2024 Dec 18;15(1):768
Discover oncology 2024 Dec 18;15(1):768
Exploring PDE5A upregulation in bipolar disorder: insights from single-nucleus RNA sequencing of human basal ganglia.
Bai Z, Li P, Gao X, Zu G, Jiang A, Wu K, Mechawar N, Turecki G, Lehnert K, Snell RG, Zhou J, Hu J, Yan B, Chen L, Li W, Chen Y, Liu S, Zhu Y, You L
Translational psychiatry 2024 Dec 18;14(1):494
Translational psychiatry 2024 Dec 18;14(1):494
Dynamic Detection of the E3-PROTAC-Target Protein Ternary Complex In Vitro and In Vivo via Bimolecular Fluorescence Complementation.
Lei K, Sheng Y, Li Y, Zhou Z, Zhu X, Huang K
ACS omega 2024 Dec 17;9(50):49739-49748
ACS omega 2024 Dec 17;9(50):49739-49748
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism.
Li M, Zhang Y, Wang Z, Wang K, Gao J, Gu H, Zeng Z, Jiang H, Fan Q, Zhang Y, Hu X, Cui L, Deng Y, Sun Y
Cancer letters 2024 Dec 16;611:217402
Cancer letters 2024 Dec 16;611:217402
LncRNA Expression Profiles in C6 Ceramide Treatment Reveal lnc_025370 as a Promoter in Canine Mammary Carcinoma CHMp Cells Progression.
Diao H, Zhao F, Wu M, Zhang Y, Tao Q, Chen S, Lin D
Current issues in molecular biology 2024 Dec 16;46(12):14190-14203
Current issues in molecular biology 2024 Dec 16;46(12):14190-14203
Mechano-induced arachidonic acid metabolism promotes keratinocyte proliferation through cPLA2 activity regulation.
Shan S, Jin R, Cheng X, He J, Luo X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70226
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70226
Design, synthesis and biological evaluation of novel benzimidazole-derived p21-activited kinase 4 (PAK4) inhibitors bearing a 4-(4-methylpiperazin-1-yl)phenyl scaffold as potential antitumor agents.
Hao S, Hou L, Wang JH, Yan JH, Niu YF, Cai ZH, Li F, Meng FH
European journal of medicinal chemistry 2024 Dec 15;280:116971
European journal of medicinal chemistry 2024 Dec 15;280:116971
Methyltransferase METTL3 regulates neuropathic pain through m6A methylation modification of SOCS1.
Wu L, Ning P, Liang Y, Wang T, Chen L, Lu D, Tang H
Neuropharmacology 2024 Dec 15;261:110176
Neuropharmacology 2024 Dec 15;261:110176
The molecular mechanisms by which the NLRP3 inflammasome regulates blood-brain barrier permeability following cryptococcal meningitis.
Liu L, Tang Y, Zhang L, Huang P, Li X, Xiao Y, Mao D, Liu L, Xiong J
Heliyon 2024 Dec 15;10(23):e39653
Heliyon 2024 Dec 15;10(23):e39653
Systematic exploration of the molecular characteristics of CD8(+) T cells to predict the response to immunotherapy and the prognosis of patients with colon adenocarcinoma.
Shen X, Shang L, Han J, Zhang Y, Niu W, Liu H, Shi H
Heliyon 2024 Dec 15;10(23):e39260
Heliyon 2024 Dec 15;10(23):e39260
Inhibition of AhR disrupts intestinal epithelial barrier and induces intestinal injury by activating NF-κB in COPD.
Tao L, Zhang Q, Liu L, Wang K, Wang J, Liu X, Zhao P, Li J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70256
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70256
Molecular Analysis of the Differential Activity of Sox8 and Sox10 in Oligodendroglial Cells.
Dehm V, Aberle T, Bladé LG, Aprato J, Weider M, Sticht H, Sock E, Wegner M
International journal of molecular sciences 2024 Dec 13;25(24)
International journal of molecular sciences 2024 Dec 13;25(24)
OGT promotes the ferroptosis of chondrocytes in osteoarthritis development via O-GlcNAcylation modification of ACSF2.
Zhang Y, Qiao Z, He M, Xia J
Immunologic research 2024 Dec 12;73(1):7
Immunologic research 2024 Dec 12;73(1):7
GsMTx4 Combined with Exercise Exerts Neuroprotective Effects by Regulating Neuronal Autophagy in Rats with Spinal Cord Injury.
Li Q, Li C, Li X, Liu X, Qian J, Li J, Li X, Zhang X
Neurochemical research 2024 Dec 12;50(1):55
Neurochemical research 2024 Dec 12;50(1):55
Accumulation of Advanced Oxidation Protein Products Promotes Age-Related Decline of Type H Vessels in Bone.
Zhao K, Zhu GZ, Li HZ, Gao JW, Tu C, Wu DZ, Huang YS, Han D, Chen XY, Wu LY, Zhong ZM
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Dec 11;80(1)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Dec 11;80(1)
Therapeutic potential of farnesoid X receptor agonists for modulating inflammation and periodontal regeneration.
Huang J, Zhang H, Fan X, Wang Y
Clinical oral investigations 2024 Dec 11;29(1):10
Clinical oral investigations 2024 Dec 11;29(1):10
Spike-In Proteome Enhances Data-Independent Acquisition for Thermal Proteome Profiling.
Wang Q, Chen Q, Lin Y, He D, Ji H, Tan CSH
Analytical chemistry 2024 Dec 10;96(49):19695-19705
Analytical chemistry 2024 Dec 10;96(49):19695-19705
TRIM24-DTNBP1-ATP7A mediated astrocyte cuproptosis in cognition and memory dysfunction caused by Y(2)O(3) NPs.
Chen Z, Liu J, Zheng M, Mo M, Hu X, Liu C, Pathak JL, Wang L, Chen L
The Science of the total environment 2024 Dec 1;954:176353
The Science of the total environment 2024 Dec 1;954:176353
TIGAR relieves PCOS by inhibiting granulosa cell apoptosis and oxidative stress through activating Nrf2.
Li Y, Song H, Xu J, Wang Y, Bai L, Wang H, Zhang J
Molecular and cellular endocrinology 2024 Dec 1;594:112381
Molecular and cellular endocrinology 2024 Dec 1;594:112381
CLEC14A facilitates angiogenesis and alleviates inflammation in diabetic wound healing.
Liao Y, Wu N, Guo L, Yang D
Life sciences 2024 Dec 1;358:123176
Life sciences 2024 Dec 1;358:123176
17β-Estradiol Ameliorates Postoperative Cognitive Dysfunction in Aged Mice via miR-138-5p/SIRT1/HMGB1 Pathway.
Zhang Y, Liu M, Yu D, Wang J, Li J
The international journal of neuropsychopharmacology 2024 Dec 1;27(12)
The international journal of neuropsychopharmacology 2024 Dec 1;27(12)
TRPM7 contributes to pyroptosis and its involvement in status epilepticus.
Tong X, Tong Y, Zheng J, Shi R, Liang H, Li M, Meng Y, Shi J, Zhao D, Seehus CR, Wang J, Xu X, Boczek T, Suzuki S, Fleig A, Penner R, Zhang N, Xu J, Duan J, Yu Z, Wang W, Zhao W, Guo F
Journal of neuroinflammation 2024 Dec 1;21(1):315
Journal of neuroinflammation 2024 Dec 1;21(1):315
O-GlcNAc participates in the meiosis of aging oocytes by mediating mitochondrial function.
Li C, Qian Z, Zhang H, Ge X, Chen L, Xue M, Tang T, He Z, Zheng L, Cao C, Zhang K, Ma R, Yao B
Reproduction (Cambridge, England) 2024 Dec 1;168(6)
Reproduction (Cambridge, England) 2024 Dec 1;168(6)
Hydrogen sulfide ameliorated endothelial dysfunction in hyperhomocysteinemia rats: Mechanism of IRE1α/JNK pathway-mediated autophagy.
Gao Y, Xu J, He K, Guo Q, Xiao L, Jin S, Tian D, Teng X, An C, Xue H, Wu Y
Nitric oxide : biology and chemistry 2024 Dec 1;153:72-81
Nitric oxide : biology and chemistry 2024 Dec 1;153:72-81
The USP11/Nrf2 positive feedback loop promotes colorectal cancer progression by inhibiting mitochondrial apoptosis.
Lu Y, Wei W, Li M, Chen D, Li W, Hu Q, Dong S, Liu L, Zhao Q
Cell death & disease 2024 Dec 1;15(12):873
Cell death & disease 2024 Dec 1;15(12):873
Discovery and optimization of anthraquinone derivatives containing substituted bisbenzyloxy groups as a novel scaffold damaged endoplasmic reticulum and against hepatocellular carcinoma cells.
Shen X, Zhai H, Tian W, Lai L, Ma T, Chen X, Wang C, Hou H
Bioorganic & medicinal chemistry 2024 Dec 1;115:117969
Bioorganic & medicinal chemistry 2024 Dec 1;115:117969
Sleep deprivation induced fat accumulation in the visceral white adipose tissue by suppressing SIRT1/FOXO1/ATGL pathway activation.
Wang W, Liu K, Xu H, Zhang C, Zhang Y, Ding M, Xing C, Huang X, Wen Q, Lu C, Song L
Journal of physiology and biochemistry 2024 Aug;80(3):561-572
Journal of physiology and biochemistry 2024 Aug;80(3):561-572
Sulforaphane impaired immune checkpoint blockade therapy through activating ΔNP63α/PD-L1 axis in gastric cancer.
Zhang Q, Yang C, Ma Z, Ye L, Wu Y, Zhong C, Shi Y, Zhu M
Molecular carcinogenesis 2024 Aug;63(8):1611-1620
Molecular carcinogenesis 2024 Aug;63(8):1611-1620
Improvement of functional dyspepsia with Suaeda salsa (L.) Pall via regulating brain-gut peptide and gut microbiota structure.
Zhang W, Wang X, Yin S, Wang Y, Li Y, Ding Y
European journal of nutrition 2024 Aug;63(5):1929-1944
European journal of nutrition 2024 Aug;63(5):1929-1944
MicroRNA miR-145-5p Inhibits Cutaneous Wound Healing by Targeting PDGFD in Diabetic Foot Ulcer.
Wang C, Huang L, Li J, Liu D, Wu B
Biochemical genetics 2024 Aug;62(4):2437-2454
Biochemical genetics 2024 Aug;62(4):2437-2454
CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex.
Guo H, Hu WC, Xian H, Shi YX, Liu YY, Ma SB, Pan KQ, Wu SX, Xu LY, Luo C, Xie RG
Molecular neurobiology 2024 Aug;61(8):4976-4991
Molecular neurobiology 2024 Aug;61(8):4976-4991
HO-1-induced autophagy establishes a HO-1-p62-Nrf2 positive feedback loop to reduce gut permeability in cholestatic liver disease.
Ren P, Lei W, Zhao C, Duan Z
Scandinavian journal of gastroenterology 2024 Aug;59(8):906-917
Scandinavian journal of gastroenterology 2024 Aug;59(8):906-917
Capsaicin attenuates Porphyromonas gingivalis-suppressed osteogenesis of periodontal ligament stem cells via regulating mitochondrial function and activating PI3K/AKT/mTOR pathway.
Wang W, Zhou Z, Ding T, Feng S, Liu H, Liu M, Ge S
Journal of periodontal research 2024 Aug;59(4):798-811
Journal of periodontal research 2024 Aug;59(4):798-811
Matrix stiffness regulates macrophage polarisation via the Piezo1-YAP signalling axis.
Mei F, Guo Y, Wang Y, Zhou Y, Heng BC, Xie M, Huang X, Zhang S, Ding S, Liu F, Deng X, Chen L, Yang C
Cell proliferation 2024 Aug;57(8):e13640
Cell proliferation 2024 Aug;57(8):e13640
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Lv S, Jiang H, Yu L, Zhang Y, Sun L, Xu J
Journal of molecular histology 2024 Aug;55(4):391-401
Journal of molecular histology 2024 Aug;55(4):391-401
Digitoxin inhibits ICC cell properties via the NF‑κB/ST6GAL1 signaling pathway.
Zhan Y, Wang R, Huang C, Xu X, Xiao X, Wu L, Wei J, Long T, Gao C
Oncology reports 2024 Aug;52(2)
Oncology reports 2024 Aug;52(2)
DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis.
Cui Y, Hu Z, Wang L, Zhu B, Deng L, Zhang H, Wang X
Neurochemical research 2024 Aug;49(8):2215-2227
Neurochemical research 2024 Aug;49(8):2215-2227
Lycorine relieves the CCl(4)-induced liver fibrosis mainly via the JAK2/STAT3 and PI3K/AKT signaling pathways.
Tang Y, Zhu Z, Li M, Gao L, Wu X, Chen J, Zhang Y, Zhao H, Xiao Z
Toxicology and applied pharmacology 2024 Aug;489:117017
Toxicology and applied pharmacology 2024 Aug;489:117017
Zinc finger protein 367 exerts a cancer-promoting role in small cell lung cancer by influencing the CIT/LATS2/YAP signaling cascade.
Kong R, Ma Y, Li W, Xu Z, Gong S, Liu A, Cheng C, Zhang X, Qin J, Li S, Feng J, Jiang J
Toxicology and applied pharmacology 2024 Aug;489:117005
Toxicology and applied pharmacology 2024 Aug;489:117005
Decreasing of serine/threonine kinase 39 has tumour inhibiting effects on acute myeloid leukaemia by impacting the PI3K/AKT and Wnt/β-catenin signalling cascades.
Li C, Xin H, Hao J, Miao Y
Toxicology and applied pharmacology 2024 Aug;489:116982
Toxicology and applied pharmacology 2024 Aug;489:116982
Osthole exhibits the remedial potential for polycystic ovary syndrome mice through Nrf2-Foxo1-GSH-NF-κB pathway.
Jin S, Wang YS, Huang JC, Wang TT, Li BY, Guo B, Yue ZP
Cell biology international 2024 Aug;48(8):1111-1123
Cell biology international 2024 Aug;48(8):1111-1123
Hematoporphyrin derivative-mediated photodynamic techniques for the diagnosis and treatment of chordoma.
Li L, Wei KL, Liu MS, Wang QL, Zeng TF, Chen RZ, Xia XW, Zhang HT
Photodiagnosis and photodynamic therapy 2024 Aug;48:104231
Photodiagnosis and photodynamic therapy 2024 Aug;48:104231
Adrenomedullin improved endothelial dysfunction via receptor-Akt pathway in rats with obesity-related hypertension.
Liu SY, Wang Q, Zhou H, Tong N, Chang R, Wang FZ, Guo P, Li X, Zhou YB, Li ZZ
Hypertension research : official journal of the Japanese Society of Hypertension 2024 Aug;47(8):2157-2171
Hypertension research : official journal of the Japanese Society of Hypertension 2024 Aug;47(8):2157-2171
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
Dong J, Che J, Wu Y, Deng Y, Jiang X, He Z, Zhang J
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Li TH, Zhao BB, Qin C, Wang YY, Li ZR, Cao HT, Yang XY, Zhou XT, Wang WB
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1253-1265
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1253-1265
Integration of serum pharmacochemistry with network pharmacology to reveal the potential mechanism of Yangqing Chenfei formula for the treatment of silicosis.
Yuanyuan HU, Xinguang L, Peng Z, Jinyan WU, Xinhua Y, Runsu H, Xiangcheng W, Fan Y, Xinrong T, Jiansheng LI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Aug;44(4):784-793
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Aug;44(4):784-793
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Ding P, Wu H, Wu J, Li T, He J, Ju Y, Liu Y, Li F, Deng H, Gu R, Zhang L, Guo H, Tian Y, Yang P, Meng N, Li X, Guo Z, Meng L, Zhao Q
Oncogene 2024 Aug;43(34):2548-2563
Oncogene 2024 Aug;43(34):2548-2563
Autocatalytic, Brain Tumor-Targeting Delivery of Bardoxolone Methyl Self-Assembled Nanoparticles for Glioblastoma Treatment.
Ye Z, Sheu WC, Qu H, Peng B, Liu J, Zhang L, Yuan F, Wei Y, Zhou J, Chen Q, Xiao X, Zhang S
Small science 2024 Aug;4(8):2400081
Small science 2024 Aug;4(8):2400081
Identification of residues in Lassa virus glycoprotein 1 involved in receptor switch.
Guo J, Wan Y, Liu Y, Jia X, Dong S, Xiao G, Wang W
Virologica Sinica 2024 Aug;39(4):600-608
Virologica Sinica 2024 Aug;39(4):600-608
miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway.
Li J, Feng R, Zhang X, Hou W, Zhang Y, Li J, Li X, Jian F, Zhang L, Zhang S, Wang R
Veterinary parasitology 2024 Aug;330:110237
Veterinary parasitology 2024 Aug;330:110237
Clonorchis sinensis aggravated liver fibrosis by activating PARP-1 signaling to induce parthanatos via DNA damage.
Bao P, Wang X, Zhang X, Yu Y, Ma Y, Zhang H, Wang Y, Liu X, Gong P, Zhang N, Lee SO, Li X, Li J
Veterinary parasitology 2024 Aug;330:110217
Veterinary parasitology 2024 Aug;330:110217
Circ_0000595 knockdown alleviates CoCl2-mediated effects in VSMCs by regulating the miR-582-3p/ADAM10 axis.
Wang H, Wang H, Liu K, Qin X
Vascular 2024 Aug;32(4):920-931
Vascular 2024 Aug;32(4):920-931
Silicone dressing combined with topical oxygen therapy alleviates incontinence-associated dermatitis via NF-κB p65/STAT1 signaling pathway.
Chen GA, Chen Y, Zhang Y, Zheng S, Zhu L, Ding M
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Aug;30(8):e13888
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Aug;30(8):e13888
Computational biology-based study of the molecular mechanism of spermidine amelioration of acute pancreatitis.
Shen Y, Duan H, Yuan L, Asikaer A, Liu Y, Zhang R, Liu Y, Wang Y, Lin Z
Molecular diversity 2024 Aug;28(4):2583-2601
Molecular diversity 2024 Aug;28(4):2583-2601
SENP1 reduces oxidative stress and apoptosis in renal ischaemia-reperfusion injury by deSUMOylation of HIF-1α.
Hui Y, Xia K, Zhong J, Zhang Y, Qiu Q, Chen Z, Wang L, Liu X
Journal of cellular and molecular medicine 2024 Aug;28(16):e70043
Journal of cellular and molecular medicine 2024 Aug;28(16):e70043
PLCγ1 deficiency in chondrocytes accelerates the age-related changes in articular cartilage and subchondral bone.
Zhao Q, Chen X, Qu N, Qiu J, Zhang B, Xia C
Journal of cellular and molecular medicine 2024 Aug;28(16):e70027
Journal of cellular and molecular medicine 2024 Aug;28(16):e70027
Ophiopogonin D' inhibited tumour growth and metastasis of anaplastic thyroid cancer by modulating JUN/RGS4 signalling.
Xu T, Zhang W, Zhang Y, Song F, Huang P
Journal of cellular and molecular medicine 2024 Aug;28(16):e70014
Journal of cellular and molecular medicine 2024 Aug;28(16):e70014
The long noncoding RNA lncMPD2 inhibits myogenesis by targeting the miR-34a-5p/THBS1 axis.
Niu Y, Zhang Y, Tian W, Wang Y, Liu Y, Ji H, Cai H, Han R, Tian Y, Liu X, Kang X, Li Z
International journal of biological macromolecules 2024 Aug;275(Pt 2):133688
International journal of biological macromolecules 2024 Aug;275(Pt 2):133688
Tetrastigma hemsleyanum polysaccharide combined with doxorubicin promote ferroptosis and immune function in triple-negative breast cancer.
Shang Y, Zhao M, Chen S, Chen Y, Liu X, Zhou F, Li Y, Long M, Xu K, Ding Z, Wang L
International journal of biological macromolecules 2024 Aug;275(Pt 1):133424
International journal of biological macromolecules 2024 Aug;275(Pt 1):133424
Genome-wide epigenetic signatures facilitated the variant classification of the PURA gene and uncovered the pathomechanism of PURA-related neurodevelopmental disorders.
Xiao B, Dai W, Zhan Y, Qiu W, Zhang H, Liu D, Xu N, Yu Y
Genetics in medicine : official journal of the American College of Medical Genetics 2024 Aug;26(8):101167
Genetics in medicine : official journal of the American College of Medical Genetics 2024 Aug;26(8):101167
miR-218-5p promotes hepatic lipogenesis through targeting Elovl5 in non-alcoholic fatty liver disease.
Wu G, Zhang Y, Liang B, Yin L, Gao M, Zhang H, Xu Y, Han X, Qi Y, Liu F, Xu L
Biochemical pharmacology 2024 Aug;226:116411
Biochemical pharmacology 2024 Aug;226:116411
Increased PHLPP1 expression through ERK-4E-BP1 signaling axis drives nicotine induced oxidative stress related damage of cardiomyocytes.
Mohammed Abdul KS, Han K, Guerrero AB, Wilson CN, Kulkarni A, Purcell NH
Journal of molecular and cellular cardiology 2024 Aug;193:100-112
Journal of molecular and cellular cardiology 2024 Aug;193:100-112
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Liu J, Wang J, Wang Z, Ren H, Zhang Z, Fu Y, Li L, Shen Z, Li T, Tang S, Wei F
Bone 2024 Aug;185:117132
Bone 2024 Aug;185:117132
Bongkrekic acid alleviates airway inflammation via breaking the mPTP/mtDAMPs/RAGE feedback loop in a steroid-insensitive asthma model.
Chen Y, Huang J, Li Y, Chen Y, Gong Z, Xu M, Ma Y, Hu D, Peng X, Xu G, Cai S, Liu L, Zhao W, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117111
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117111
The secoiridoid glycoside Gentiopicroside is a USP22 inhibitor with potent antitumor immunotherapeutic activity.
Lu W, Chu P, Tang A, Si L, Fang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116974
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116974
The PD-1 /PD-L1 signaling pathway regulates decidual macrophage polarization and may participate in preeclampsia.
Du X, Liu H, Shi J, Yang P, Gu Y, Meng J
Journal of reproductive immunology 2024 Aug;164:104258
Journal of reproductive immunology 2024 Aug;164:104258
Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway.
Han X, Liu J, Zhang Y, Tse E, Yu Q, Lu Y, Ma Y, Zheng L
Journal of pharmaceutical analysis 2024 Aug;14(8):100984
Journal of pharmaceutical analysis 2024 Aug;14(8):100984
Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement.
Liu N, Cui X, Yan W, Guo T, Wang Z, Wei X, Sun Y, Liu J, Xian C, Ma W, Chen L
Journal of pharmaceutical analysis 2024 Aug;14(8):100968
Journal of pharmaceutical analysis 2024 Aug;14(8):100968
Apolipoprotein A-IV restrains fat accumulation in skeletal and myocardial muscles by inhibiting lipogenesis and activating PI3K-AKT signalling.
Zhang W, Liu XH, Zhou JT, Cheng C, Xu J, Yu J, Li X
Archives of physiology and biochemistry 2024 Aug;130(4):491-501
Archives of physiology and biochemistry 2024 Aug;130(4):491-501
Expression profiles of miRNAs in the lung tissue of piglets infected with Glaesserella parasuis and the roles of ssc-miR-135 and ssc-miR-155-3p in the regulation of inflammation.
Wang J, Yan P, Jia Y, Guo Z, Guo Y, Yin R, Wang L, Fan Z, Zhou Y, Yuan J, Yin R
Comparative immunology, microbiology and infectious diseases 2024 Aug;111:102214
Comparative immunology, microbiology and infectious diseases 2024 Aug;111:102214
Ultrasonic-assisted extraction of a low molecular weight polysaccharide from Nostoc commune Vaucher and its structural characterization and immunomodulatory activity.
Pan Y, Liu C, Jiang S, Guan L, Liu X, Wen L
Ultrasonics sonochemistry 2024 Aug;108:106961
Ultrasonics sonochemistry 2024 Aug;108:106961
Berberine alleviates high-energy and low-protein diet-induced fatty liver hemorrhagic syndrome in laying hens: insights from microbiome and metabolomics.
Cheng X, Hu Y, Kuang J, Guo X, Cao H, Wu H, Hu G, Zhuang Y
Poultry science 2024 Aug;103(8):103968
Poultry science 2024 Aug;103(8):103968
Effects of Smilax China L. extracts on Hyperuricemia chicken model via inhibiting xanthine oxidase activity.
Yan M, Zheng X, Lin Y, Zheng X, Xi K, Gao Y, Wang H, Li Y, Liu C
Poultry science 2024 Aug;103(8):103887
Poultry science 2024 Aug;103(8):103887
Inhibitory effects of Belamcanda extract on inflammatory response and antiviral mechanism in H9N2 Avian influenza virus: insights from in vitro and in vivo studies.
Zhi Y, Wei J, Liu Z, Zhang Q, Zhang T, Hu G
Poultry science 2024 Aug;103(8):103885
Poultry science 2024 Aug;103(8):103885
Isoliquiritigenin attenuates myocardial ischemia reperfusion through autophagy activation mediated by AMPK/mTOR/ULK1 signaling.
Shen L, Zhu Y, Chen Z, Shen F, Yu W, Zhang L
BMC cardiovascular disorders 2024 Aug 9;24(1):415
BMC cardiovascular disorders 2024 Aug 9;24(1):415
CYLD/HDAC6 signaling regulates the interplay between epithelial-mesenchymal transition and ciliary homeostasis during pulmonary fibrosis.
Ni H, Chen M, Dong D, Zhou Y, Cao Y, Ge R, Luo X, Wang Y, Dong X, Zhou J, Li D, Xie S, Liu M
Cell death & disease 2024 Aug 9;15(8):581
Cell death & disease 2024 Aug 9;15(8):581
The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.
Deng H, Jia G, Li P, Tang Y, Zhao L, Yang Q, Zhao J, Wang J, Tu Y, Yong X, Zhang S, Mo X, Billadeau DD, Su Z, Jia D
Cell 2024 Aug 8;187(16):4272-4288.e20
Cell 2024 Aug 8;187(16):4272-4288.e20
Antidepressant Sertraline Synergistically Enhances Paclitaxel Efficacy by Inducing Autophagy in Colorectal Cancer Cells.
He L, Tian Y, Liu Q, Bao J, Ding RB
Molecules (Basel, Switzerland) 2024 Aug 7;29(16)
Molecules (Basel, Switzerland) 2024 Aug 7;29(16)
SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis.
He X, Zhang Y, Mao Z, Liu G, Huang L, Liu X, Su Y, Xing X
Acta biochimica et biophysica Sinica 2024 Aug 6;56(11):1673-1686
Acta biochimica et biophysica Sinica 2024 Aug 6;56(11):1673-1686
NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling.
Wang S, Qiao X, Cui Y, Liu L, Cooper T, Hu Y, Lin J, Liu H, Wang M, Hayball J, Wang X
Cell death & disease 2024 Aug 6;15(8):565
Cell death & disease 2024 Aug 6;15(8):565
Adhesion of pancreatic tumor cell clusters by desmosomal molecules enhances early liver metastases formation.
Dietrich N, Castellanos-Martinez R, Kemmling J, Heuser A, Schnoor M, Schinner C, Spindler V
Scientific reports 2024 Aug 6;14(1):18189
Scientific reports 2024 Aug 6;14(1):18189
miR-143-3p modulates depressive-like behaviors via Lasp1 in the mouse ventral hippocampus.
Yu H, Li X, Zhang Q, Geng L, Su B, Wang Y
Communications biology 2024 Aug 5;7(1):944
Communications biology 2024 Aug 5;7(1):944
DAPK1 mediates cognitive dysfunction and neuronal apoptosis in PSD rats through the ERK/CREB/BDNF signaling pathway.
Zhang X, Fan L, Yang L, Jin X, Liu H, Lei H, Song X, Zhang Z, Zhang F, Song J
Behavioural brain research 2024 Aug 5;471:115064
Behavioural brain research 2024 Aug 5;471:115064
Anticancer effects of Erzhimaoling decoction in high-grade serous ovarian cancer in vitro and in vivo.
Yang L, Liu J, Zhang J, Shao F, Jin Y, Xing J, Zhou H, Yu A
European journal of medical research 2024 Aug 5;29(1):405
European journal of medical research 2024 Aug 5;29(1):405
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Li L, Zhai M, Cheng C, Cui S, Wang J, Zhang Z, Liu J, Wei F
Progress in orthodontics 2024 Aug 5;25(1):30
Progress in orthodontics 2024 Aug 5;25(1):30
Actomyosin-II protects axons from degeneration induced by mild mechanical stress.
Pan X, Hu Y, Lei G, Wei Y, Li J, Luan T, Zhang Y, Chu Y, Feng Y, Zhan W, Zhao C, Meunier FA, Liu Y, Li Y, Wang T
The Journal of cell biology 2024 Aug 5;223(8)
The Journal of cell biology 2024 Aug 5;223(8)
Metformin enhances endogenous neural stem cells proliferation, neuronal differentiation, and inhibits ferroptosis through activating AMPK pathway after spinal cord injury.
Xing C, Liu S, Wang L, Ma H, Zhou M, Zhong H, Zhu S, Wu Q, Ning G
Journal of translational medicine 2024 Aug 5;22(1):723
Journal of translational medicine 2024 Aug 5;22(1):723
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
Wei W, Lu Y, Zhang M, Guo J, Zhang H
Scientific reports 2024 Aug 5;14(1):18094
Scientific reports 2024 Aug 5;14(1):18094
LINC01605 promotes malignant phenotypes of cervical cancer via miR-149-3p/WNT7B axis.
Kong X, Xiong Y, Li L
Gene 2024 Aug 30;921:148518
Gene 2024 Aug 30;921:148518
KAT7 serves as an oncogenic gene and regulates CCL3 expression via STAT1 signaling in osteosarcoma.
Yuan Q, Wu Y, Xue C, Zhao D, Wang H, Shen Y
Biochemical and biophysical research communications 2024 Aug 30;722:150156
Biochemical and biophysical research communications 2024 Aug 30;722:150156
Targeting m7G-enriched circKDM1A prevents colorectal cancer progression.
Sun Z, Xu Y, Si C, Wu X, Guo Y, Chen C, Wang C
Molecular cancer 2024 Aug 30;23(1):179
Molecular cancer 2024 Aug 30;23(1):179
MicroRNA-650 promotes melanoma metastasis via targeting inhibitor of growth family member 4.
Chen C, Liu J, Ma Y, Wang Y, Cai L
Heliyon 2024 Aug 30;10(16):e36199
Heliyon 2024 Aug 30;10(16):e36199
Synergistic effects of plasma-activated medium in combination with Baicalin against neuronal damage.
Zhu J, Liu Q, Chen Y, Zhang J, Xu Q, Wu Z
Heliyon 2024 Aug 30;10(16):e36079
Heliyon 2024 Aug 30;10(16):e36079
GFPT1 accelerates immune escape in breast cancer by modifying PD-L1 via O-glycosylation.
Tang W, Gao Y, Hong S, Wang S
BMC cancer 2024 Aug 29;24(1):1071
BMC cancer 2024 Aug 29;24(1):1071
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Zhu W, Wu C, Liu Z, Zhao S, Huang J
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Extracellular Vesicle Inhibitors Enhance Cholix-Induced Cell Death via Regulation of the JNK-Dependent Pathway.
Ozaki K, Nagahara H, Kawamura A, Ohgita T, Higashi S, Ogura K, Tsutsuki H, Iyoda S, Yokotani A, Yamaji T, Moss J, Yahiro K
Toxins 2024 Aug 29;16(9)
Toxins 2024 Aug 29;16(9)
CTDSPL2 promotes the progression of non-small lung cancer through PI3K/AKT signaling via JAK1.
Li M, Chen L, Yu F, Mei H, Ma X, Ding K, Yang Y, Rong Z
Cell death discovery 2024 Aug 29;10(1):389
Cell death discovery 2024 Aug 29;10(1):389
Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation.
Chen Y, He W, Qiu J, Luo Y, Jiang C, Zhao F, Wei H, Meng J, Long T, Zhang X, Yang L, Xu Q, Wang J, Zhang C
Cellular & molecular biology letters 2024 Aug 28;29(1):114
Cellular & molecular biology letters 2024 Aug 28;29(1):114
Homologous Tumor Cell-Derived Biomimetic Nano-Trojan Horse Integrating Chemotherapy with Genetherapy for Boosting Triple-Negative Breast Cancer Therapy.
Duan W, Shen Q, Ju L, Huang Z, Geng J, Wu Q, Yu C, Wei J
ACS applied materials & interfaces 2024 Aug 28;16(34):45523-45536
ACS applied materials & interfaces 2024 Aug 28;16(34):45523-45536
Potential mechanism prediction of indole-3-propionic acid against diminished ovarian reserve via network pharmacology, molecular docking and experimental verification.
Liu A, Liu Z, Shen H, Du W, Jiang Y, Wang L, Zhang R, Jin P, Zhang X
BMC complementary medicine and therapies 2024 Aug 27;24(1):316
BMC complementary medicine and therapies 2024 Aug 27;24(1):316
Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs-GPR-GLP1 signal axis.
Tian S, Lei Y, Zhao F, Che J, Wu Y, Lei P, Kang YE, Shan Y
Food & function 2024 Aug 27;15(17):8644-8660
Food & function 2024 Aug 27;15(17):8644-8660
The Kv4 potassium channel modulator NS5806 attenuates cardiac hypertrophy in vivo and in vitro.
Cai Y, Zhang J, Zhang H, Qi J, Shi C, Xu Y
Scientific reports 2024 Aug 27;14(1):19839
Scientific reports 2024 Aug 27;14(1):19839
Proteolysis targeting chimera extracellular vesicles for therapeutic development treating triple negative breast cancer.
Erwin N, De U, Xiao Y, Wang L, Maharjan C, Pan X, Awasthee N, Zheng G, Liao D, Zhang W, He M
bioRxiv : the preprint server for biology 2024 Aug 26;
bioRxiv : the preprint server for biology 2024 Aug 26;
Youthful small extracellular vesicles restore the function and reparative capacity of inflammatory-impaired periodontal ligament stem cells via delivering protein biglycan for bone regeneration.
Yang J, Su J, Sun Z, Song Y, Zhang Y, Zhang Z, Wei J, Shi X, Jiang N, Ge X
Journal of nanobiotechnology 2024 Aug 24;22(1):508
Journal of nanobiotechnology 2024 Aug 24;22(1):508
Extracellular vesicle-bound VEGF in oral squamous cell carcinoma and its role in resistance to Bevacizumab Therapy.
Zhou J, Liu X, Dong Q, Li J, Niu W, Liu T
Cancer cell international 2024 Aug 23;24(1):296
Cancer cell international 2024 Aug 23;24(1):296
PINX1 loss confers susceptibility to PARP inhibition in pan-cancer cells.
Huang M, Zhu X, Wang C, He L, Li L, Wang H, Fan G, Wang Y
Cell death & disease 2024 Aug 22;15(8):610
Cell death & disease 2024 Aug 22;15(8):610
Ribonuclease Inhibitor 1 (RNH1) Regulates Sperm tsRNA Generation for Paternal Inheritance through Interacting with Angiogenin in the Caput Epididymis.
Ma Z, Tang N, Zhang R, Deng H, Chen K, Liu Y, Ding Z
Antioxidants (Basel, Switzerland) 2024 Aug 22;13(8)
Antioxidants (Basel, Switzerland) 2024 Aug 22;13(8)
Two-polarized roles of transcription factor FOSB in lung cancer progression and prognosis: dependent on p53 status.
Zhang H, Zhang G, Xiao M, Cui S, Jin C, Yang J, Wu S, Lu X
Journal of experimental & clinical cancer research : CR 2024 Aug 21;43(1):237
Journal of experimental & clinical cancer research : CR 2024 Aug 21;43(1):237
Extracellular Vesicle-Associated Neutrophil Elastase Activates Hepatic Stellate Cells and Promotes Liver Fibrogenesis via ERK1/2 Pathway.
Oshins R, Greenberg Z, Tai YL, Zhao D, Wang X, Mehrad B, He M, Patel I, Khartabil L, Zhou H, Brantly M, Khodayari N
bioRxiv : the preprint server for biology 2024 Aug 21;
bioRxiv : the preprint server for biology 2024 Aug 21;
ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency.
Zhou M, Yang T, Yuan M, Li X, Deng J, Wu S, Zhong Z, Lin Y, Zhang W, Xia B, Wu Y, Wang L, Chen T, Liu R, Pan T, Ma X, Li L, Liu B, Zhang H
Journal of virology 2024 Aug 20;98(8):e0003524
Journal of virology 2024 Aug 20;98(8):e0003524
Interleukin-33 promotes intrauterine adhesion formation in mice through the mitogen-activated protein kinase signaling pathway.
Liu D, Yuan L, Xu F, Ma Y, Zhang H, Jin Y, Chen M, Zhang Z, Luo S
Communications biology 2024 Aug 20;7(1):1022
Communications biology 2024 Aug 20;7(1):1022
Quantitative Proteomics Reveal the Mechanism of MiR-138-5p Suppressing Cervical Cancer via Targeting ZNF385A.
Peng Q, Deng Y, Li G, Li J, Zheng P, Xiong Q, Li J, Chen Y, Ge F
Journal of proteome research 2024 Aug 2;23(8):3659-3673
Journal of proteome research 2024 Aug 2;23(8):3659-3673
Integrative Analysis of Lactylome and Proteome of Hypertrophic Scar To Identify Pathways or Proteins Associated with Disease Development.
Zhang E, Yan Q, Sun Y, Li J, Chen L, Zou J, Zeng S, Jiang J, Li J
Journal of proteome research 2024 Aug 2;23(8):3367-3382
Journal of proteome research 2024 Aug 2;23(8):3367-3382
Sestrin2 knockout exacerbates high-fat diet induced metabolic disorders and complications in female mice.
Zhang L, Kan C, Shi J, Qiu H, Zhang J, Ding W, Xu L, Zhang K, Guo Z, Hou N, Sun X, Han F
Nutrition & metabolism 2024 Aug 2;21(1):60
Nutrition & metabolism 2024 Aug 2;21(1):60
Immediate myeloid depot for SARS-CoV-2 in the human lung.
Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Bernard O, Simoneau CR, Hysenaj L, Hu KH, Maishan M, Conrad C, Gbenedio OM, Samad B, Consortium TUC, Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR
Science advances 2024 Aug 2;10(31):eadm8836
Science advances 2024 Aug 2;10(31):eadm8836
SelK promotes glioblastoma cell proliferation by inhibiting β-TrCP1 mediated ubiquitin-dependent degradation of CDK4.
Li J, Zhao L, Wu Z, Huang S, Wang J, Chang Y, Liu L, Jin H, Lu J, Huang C, Xie Q, Huang H, Su Z
Journal of experimental & clinical cancer research : CR 2024 Aug 19;43(1):231
Journal of experimental & clinical cancer research : CR 2024 Aug 19;43(1):231
Splicing Factor PTBP1 Silencing Induces Apoptosis of Human Cervical Cancer Cells via PI3K/AKT Pathway and Autophagy.
Liu T, Zhou Y, Chen L, Liu Q, Hu D, Huang R, Ji H, Lin Y, Sun Y
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):289
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):289
The role and mechanism of thrombospondin-4 in pulmonary arterial hypertension associated with congenital heart disease.
Zeng H, Lan B, Li B, Xie H, Zhao E, Liu X, Xue X, Sun J, Su L, Zhang Y
Respiratory research 2024 Aug 17;25(1):313
Respiratory research 2024 Aug 17;25(1):313
Telomerase related molecular subtype and risk model reveal immune activity and evaluate prognosis and immunotherapy response in prostate cancer.
Liu D, Qin Z, Yi B, Xie H, Liang Y, Zhu L, Yang K, Xu Y, Zhang H
Cancer cell international 2024 Aug 17;24(1):294
Cancer cell international 2024 Aug 17;24(1):294
SERPINH1 modulates apoptosis by inhibiting P62 ubiquitination degradation to promote bone metastasis of prostate cancer.
Tang C, Lai Y, Li L, Situ MY, Li S, Cheng B, Chen Y, Lei Z, Ren Y, Zhou J, Wu Y, Zhong H, Li K, Zeng L, Guo Z, Peng S, Huang H
iScience 2024 Aug 16;27(8):110427
iScience 2024 Aug 16;27(8):110427
Targeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling.
Brewer A, Zhao JF, Fasimoye R, Shpiro N, Macartney TJ, Wood NT, Wightman M, Alessi DR, Sapkota GP
iScience 2024 Aug 16;27(8):110423
iScience 2024 Aug 16;27(8):110423
Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis.
Wang X, Tang P, Gong Y, Yao H, Liang M, Qu H, Han X, Zheng Q, Shi Z, Li D, Jiang Q
iScience 2024 Aug 16;27(8):110382
iScience 2024 Aug 16;27(8):110382
Catalpol inhibits HHcy-induced EndMT in endothelial cells by modulating ROS/NF-κB signaling.
Wu C, Li Y, Liu S, Wang L, Wang X
BMC cardiovascular disorders 2024 Aug 16;24(1):431
BMC cardiovascular disorders 2024 Aug 16;24(1):431
The M2 Protein of the Influenza A Virus Interacts with PEX19 to Facilitate Virus Replication by Disrupting the Function of Peroxisome.
Liu T, Liang L, Zhao P, Lin W, Zhuang Y, Jiang L, Chen H, Li C
Viruses 2024 Aug 16;16(8)
Viruses 2024 Aug 16;16(8)
Construction of mitochondrial-targeting nano-prodrug for enhanced Rhein delivery and treatment for osteoarthritis in vitro.
Huang H, Yang L, He H, Zhou B, Qin Z, Zheng L, Shen C
International journal of pharmaceutics 2024 Aug 15;661:124397
International journal of pharmaceutics 2024 Aug 15;661:124397
Potential mechanisms of aortic medial degeneration promoted by co-exposure to microplastics and lead.
Xie X, Wang K, Shen X, Li X, Wang S, Yuan S, Li B, Wang Z
Journal of hazardous materials 2024 Aug 15;475:134854
Journal of hazardous materials 2024 Aug 15;475:134854
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Qian YW, Guo YQ, Li YL, Wang Y, Guo S, Niu QQ, Zhu ML, Li P
Life sciences 2024 Aug 15;351:122862
Life sciences 2024 Aug 15;351:122862
Integrating bulk and single-cell sequencing reveals metastasis-associated CAFs in head and neck squamous cell carcinoma.
Yao Y, Tian G, Zhang J, Zhang S, Liu X, Hou J
Life sciences 2024 Aug 15;351:122768
Life sciences 2024 Aug 15;351:122768
In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP.
Ning J, Zhan N, Wu Z, Li Y, Zhang D, Shi Y, Zhou Y, Chen CH, Jin W
RSC medicinal chemistry 2024 Aug 15;15(11):3674-94
RSC medicinal chemistry 2024 Aug 15;15(11):3674-94
Decreased thrombospondin-1 impairs endometrial stromal decidualization in unexplained recurrent spontaneous abortion†.
Hu J, Qin C, Xu Y, Liu X, Wei X, Wu J, Zhao X, Chen C, Lin Y
Biology of reproduction 2024 Aug 15;111(2):448-462
Biology of reproduction 2024 Aug 15;111(2):448-462
Exploring the relationship between pyroptosis and inflammatory bone loss: Evidence from a cigarette smoke-induced osteoporosis mouse model.
Wang G, Li H, Hu X, Wang Y, Zhu G, Zhou H, Liang Z, Wang Z, Nuessler A, Lin Z, Xie H, Zhu S
Heliyon 2024 Aug 15;10(15):e35715
Heliyon 2024 Aug 15;10(15):e35715
MicroRNA-2861 regulates the proliferation and apoptosis of human retinal vascular endothelial cells treated with high glucose by targeting NDUFB7.
Shi Q, Wang Q, Mao K, Liu Z, Wang R
Heliyon 2024 Aug 15;10(15):e35663
Heliyon 2024 Aug 15;10(15):e35663
Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models.
Fei F, Chen Z, Tao Y, Jiang X, Xu X, Ma Y, Feng P, Wang P
Heliyon 2024 Aug 15;10(15):e35363
Heliyon 2024 Aug 15;10(15):e35363
Dextran sulfate inhibits proliferation and metastasis of human gastric cancer cells via miR-34c-5p.
Zhao Y, Ma Q, Gao W, Li Z, Yu G, Li B, Xu Y, Huang Y
Heliyon 2024 Aug 15;10(15):e34859
Heliyon 2024 Aug 15;10(15):e34859
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Che Y, Lu X, Wang X, Liu Z, Guan L, Li X, Du Z, Ren H, Wang J, Zhou Z, Lv L
Cancer cell international 2024 Aug 14;24(1):290
Cancer cell international 2024 Aug 14;24(1):290
Nilotinib boosts the efficacy of anti-PDL1 therapy in colorectal cancer by restoring the expression of MHC-I.
Dong H, Wen C, He L, Zhang J, Xiang N, Liang L, Hu L, Li W, Liu J, Shi M, Hu Y, Chen S, Liu H, Yang X
Journal of translational medicine 2024 Aug 14;22(1):769
Journal of translational medicine 2024 Aug 14;22(1):769
Gene therapy in Aβ-induced cell and mouse models of Alzheimer's disease through compensating defective mitochondrial complex I function.
Li H, Chen Z, Shen Y, Xiong T, Chen A, Chen L, Ye Y, Jiang Q, Zhang Y, Sun J, Shen L
Journal of translational medicine 2024 Aug 14;22(1):760
Journal of translational medicine 2024 Aug 14;22(1):760
A structured biomimetic nanoparticle as inflammatory factor sponge and autophagy-regulatory agent against intervertebral disc degeneration and discogenic pain.
Li K, Yang W, Chen X, Yu Y, Liu Y, Ni F, Xiao Y, Qing X, Liu S, He Y, Wang B, Xu L, Shao Z, Zhao L, Peng Y, Lin H
Journal of nanobiotechnology 2024 Aug 14;22(1):486
Journal of nanobiotechnology 2024 Aug 14;22(1):486
The histamine receptor H1 acts as an alternative receptor for SARS-CoV-2.
Yu F, Liu X, Ou H, Li X, Liu R, Lv X, Xiao S, Hu M, Liang T, Chen T, Wei X, Zhang Z, Liu S, Liu H, Zhu Y, Liu G, Tu T, Li P, Zhang H, Pan T, Ma X
mBio 2024 Aug 14;15(8):e0108824
mBio 2024 Aug 14;15(8):e0108824
Orai1 and Orai3 act through distinct signalling axes to promote stemness and tumorigenicity of breast cancer stem cells.
Zhuo D, Lei Z, Dong L, Chan AML, Lin J, Jiang L, Qiu B, Jiang X, Tan Y, Yao X
Stem cell research & therapy 2024 Aug 13;15(1):256
Stem cell research & therapy 2024 Aug 13;15(1):256
Characterization of Novel PHEX Variants in X-linked Hypophosphatemic Rickets and Genotype-PHEX Activity Correlation.
Wu H, Ying H, Zhao W, Sun Y, Wang Y, Chen X, Li G, Yao Y, Xu S, Li T, Fang L, Sun X, Wang N, Xu J, Guan Q, Xia W, Wang L, Gao L, Zhao J, Xu C
The Journal of clinical endocrinology and metabolism 2024 Aug 13;109(9):2242-2255
The Journal of clinical endocrinology and metabolism 2024 Aug 13;109(9):2242-2255
Heavy Metal Exposure-Mediated Dysregulation of Sphingolipid Metabolism.
Ahmad S, Single S, Liu Y, Hough KP, Wang Y, Thannickal VJ, Athar M, Goliwas KF, Deshane JS
Antioxidants (Basel, Switzerland) 2024 Aug 12;13(8)
Antioxidants (Basel, Switzerland) 2024 Aug 12;13(8)
Activated STING-containing R-EVs from iPSC-derived MSCs promote antitumor immunity.
Qian L, Zhang Z, Zhang R, Zheng X, Xiao B, Zhang X, Wu Y, Chen Y, Zhang X, Zhou P, Fu Q, Kang T, Gao Y
Cancer letters 2024 Aug 10;597:217081
Cancer letters 2024 Aug 10;597:217081
The deubiquitinase USP2a promotes tumor immunosuppression by stabilizing immune checkpoint B7-H4 in lung adenocarcinoma harboring EGFR-activating mutants.
Lu Y, Sun Y, Zhang J, Kong M, Zhao Z, Sun B, Wang Y, Jiang Y, Chen S, Wang C, Tong Y, Wen L, Huang M, Wu F, Zhang L
Cancer letters 2024 Aug 1;596:217020
Cancer letters 2024 Aug 1;596:217020
A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.
Huang W, Zhou H, He Y, Wang A, Wang B, Chen Y, Liu C, Wang H, Xie W, Kong H
Experimental cell research 2024 Aug 1;441(1):114154
Experimental cell research 2024 Aug 1;441(1):114154
Asprosin contributes to vascular remodeling in hypertensive rats via superoxide signaling.
Xu ZQ, Li XZ, Zhu R, Ge R, Wei H, Shi HW, Wang Z, Yang C, Yang YW, Lu XJ, Chen AD, Zhu GQ, Tan X
Journal of hypertension 2024 Aug 1;42(8):1427-1439
Journal of hypertension 2024 Aug 1;42(8):1427-1439
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Li H, Wu D, Zhang H, Liu S, Zhen J, Yan Y, Li P
BMC gastroenterology 2024 Aug 1;24(1):245
BMC gastroenterology 2024 Aug 1;24(1):245
The parkin V380L variant is a genetic modifier of Machado-Joseph disease with impact on mitophagy.
Weber JJ, Czisch L, Pereira Sena P, Fath F, Huridou C, Schwarz N, Incebacak Eltemur RD, Würth A, Weishäupl D, Döcker M, Blumenstock G, Martins S, Sequeiros J, Rouleau GA, Jardim LB, Saraiva-Pereira ML, França MC Jr, Gordon CR, Zaltzman R, Cornejo-Olivas MR, van de Warrenburg BPC, Durr A, Brice A, Bauer P, Klockgether T, Schöls L, Riess O, EUROSCA Network, Schmidt T
Acta neuropathologica 2024 Aug 1;148(1):14
Acta neuropathologica 2024 Aug 1;148(1):14
Discovery and evaluation of novel spiroheterocyclic protective agents via a SIRT1 upregulation mechanism in cisplatin-induced premature ovarian failure.
He W, Huang Z, Nian C, Huang L, Kong M, Liao M, Zhang Q, Li W, Hu Y, Wu J
Bioorganic & medicinal chemistry 2024 Aug 1;110:117834
Bioorganic & medicinal chemistry 2024 Aug 1;110:117834
CPEB1 induces autophagy and promotes apoptosis in ovarian granulosa cells of polycystic ovary syndrome.
Xuan F, Ren Y, Lu J, Zhou W, Jin R, Chen A, Ye Y
Molecular reproduction and development 2024 Apr;91(4):e23741
Molecular reproduction and development 2024 Apr;91(4):e23741
Interleukin-19 enhances eosinophil infiltration through upregulation of epithelium-derived RANTES expression via the ERK/NF-κB signalling pathway in patients with eosinophilic CRSwNP.
Huang Z, Li X, Li Y, Huang W, Lai X, Wu H, Chen X, Zhang Y, Chang L, Zhang G
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):499-513
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):499-513
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Chen H, Zhang H, Li AM, Liu YT, Liu Y, Zhang W, Yang C, Song N, Zhan M, Yang S
Redox biology 2024 Apr;70:103062
Redox biology 2024 Apr;70:103062
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Ren YR, Cui WT, Jiang KL, He KQ, Lu YM, Chen Y, Pan WJ
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF-β1 /P-smad3 signaling through HIF-1a.
Zhu X, Bao W, Xie X, Chen B, Li R, Zhao J, Wu L, Yu Z, Li S, Zhu Q, Chen G, Li J
Molecular carcinogenesis 2024 Apr;63(4):772-784
Molecular carcinogenesis 2024 Apr;63(4):772-784
STAT4-Mediated Klotho Up-Regulation Contributes to the Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning via Inhibiting Neuronal Pyroptosis.
Liu XY, Zhang LY, Wang XY, Li SC, Hu YY, Zhang JG, Xian XH, Li WB, Zhang M
Molecular neurobiology 2024 Apr;61(4):2336-2356
Molecular neurobiology 2024 Apr;61(4):2336-2356
PRDX6 alleviated heart failure by inhibiting doxorubicin-induced ferroptosis through the JAK2/STAT1 pathway inactivation.
Xiong J, Zhou R, Deng X
In vitro cellular & developmental biology. Animal 2024 Apr;60(4):354-364
In vitro cellular & developmental biology. Animal 2024 Apr;60(4):354-364
Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis.
Wu C, Li J, Jia H, Zhao J, Qin M, Shi H, Liu C, Lin J, Cai M, Gu Y, Liu B, Gao L
Journal of gastroenterology 2024 Apr;59(4):342-356
Journal of gastroenterology 2024 Apr;59(4):342-356
Transcriptomic analysis of rat brain response to alternating current electrical stimulation: unveiling insights via single-nucleus RNA sequencing.
Wang Y, Ma Y, Zhong Q, Song B, Liu Q
MedComm 2024 Apr;5(4):e514
MedComm 2024 Apr;5(4):e514
Long Non-Coding RNA ANRIL Regulates Inflammatory Factor Expression in Ulcerative Colitis Via the miR-191-5p/SATB1 Axis.
Yu KQ, Li CF, Ye L, Song Y, Wang YH, Lin YR, Liao ST, Mei ZC, Lv L
Inflammation 2024 Apr;47(2):513-529
Inflammation 2024 Apr;47(2):513-529
Bioinformatics analysis and experimental validation reveal that CDC20 overexpression promotes bladder cancer progression and potential underlying mechanisms.
Liu Y, Zou SH, Gao X
Genes & genomics 2024 Apr;46(4):437-449
Genes & genomics 2024 Apr;46(4):437-449
E3 ubiquitin ligase NEDD4L inhibits epithelial-mesenchymal transition by suppressing the β-catenin/HIF-1α positive feedback loop in chronic rhinosinusitis with nasal polyps.
Chen SY, Liu PQ, Qin DX, Lv H, Zhou HQ, Xu Y
Acta pharmacologica Sinica 2024 Apr;45(4):831-843
Acta pharmacologica Sinica 2024 Apr;45(4):831-843
Inflammatory Factor IL1α Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca(2+)/CaMK2b Pathway.
Xia Y, Ding L, Zhang C, Xu Q, Shi M, Gao T, Zhou FQ, Deng DYB
Neuroscience bulletin 2024 Apr;40(4):421-438
Neuroscience bulletin 2024 Apr;40(4):421-438
Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis.
Yao T, Yao YY, Wang JZ, Jiang SM, Li LJ
The Kaohsiung journal of medical sciences 2024 Apr;40(4):360-373
The Kaohsiung journal of medical sciences 2024 Apr;40(4):360-373
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Wang N, Guo W, Liu T, Chen X, Lin M
Biotechnology & genetic engineering reviews 2024 Apr;40(1):519-539
Biotechnology & genetic engineering reviews 2024 Apr;40(1):519-539
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Liu X, Liu M, Chen L
Cell and tissue research 2024 Apr;396(1):103-117
Cell and tissue research 2024 Apr;396(1):103-117
Induction of apoptosis and autophagy by dichloromethane extract from Patrinia scabiosaefolia Fisch on acute myeloid leukemia cells.
Li K, Mi L, Bai X, Lu Y, Zhang Y, Li J, Pu Y
Environmental toxicology 2024 Apr;39(4):2123-2137
Environmental toxicology 2024 Apr;39(4):2123-2137
Integrated network pharmacology, molecular docking and pharmacodynamic study reveals protective effects and mechanisms of corilagin against cerebral ischemia-induced injury.
Tao D, Xia X, Zhang X, Yang R, Yang Y, Zhang L, Shi Y, Lv D, Chen P, He B, Shen Z
Experimental neurology 2024 Apr;374:114697
Experimental neurology 2024 Apr;374:114697
Valeric acid reduction by chitosan oligosaccharide induces autophagy in a Parkinson's disease mouse model.
Chen R, Li K, Wang Y, Song L, Wang R, Fan W, Zhao N, Zou W, Yang Z, Yan J
Journal of drug targeting 2024 Apr;32(4):423-432
Journal of drug targeting 2024 Apr;32(4):423-432
Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-κB signaling pathway through modification of the Src/TRAF6/TAK1 axis.
Chen H, Liu F, Dai D, Ming Y, Xu Y, Huang Z, Zhang L, Sun Y
Inflammopharmacology 2024 Apr;32(2):1475-1488
Inflammopharmacology 2024 Apr;32(2):1475-1488
Pseudolaric acid B exerts an antifungal effect and targets SIRT1 to ameliorate inflammation by regulating Nrf2/NF-κB pathways in fungal keratitis.
Liu S, Qin T, Zou F, Dong H, Yu L, Wang H, Zhang L
Inflammopharmacology 2024 Apr;32(2):1133-1146
Inflammopharmacology 2024 Apr;32(2):1133-1146
Mitochondria-associated endoplasmic reticulum membrane as a mediator of vanadium-induced endoplasmic reticulum quality control in duck brains.
Lin Y, Yang F, Dai X, Shan J, Cao H, Hu G, Zhang C, Xing C
Environmental science and pollution research international 2024 Apr;31(18):26510-26526
Environmental science and pollution research international 2024 Apr;31(18):26510-26526
Nicotine suppresses crystalline silica-induced astrocyte activation and neuronal death by inhibiting NF-κB in the mouse hippocampus.
Cao H, Li B, Mu M, Li S, Chen H, Tao H, Wang W, Zou Y, Zhao Y, Liu Y, Tao X
CNS neuroscience & therapeutics 2024 Apr;30(4):e14508
CNS neuroscience & therapeutics 2024 Apr;30(4):e14508
A TGF-β signaling-related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response.
Duan WW, Yang LT, Liu J, Dai ZY, Wang ZY, Zhang H, Zhang X, Liang XS, Luo P, Zhang J, Liu ZQ, Zhang N, Mo HY, Qu CR, Xia ZW, Cheng Q
CNS neuroscience & therapeutics 2024 Apr;30(4):e14489
CNS neuroscience & therapeutics 2024 Apr;30(4):e14489
Effect and mechanism of fluctuant glucose on restraining implant osseointegration in diabetes.
Song D, Wang C, Liang J, Jia T
Oral diseases 2024 Apr;30(3):1583-1590
Oral diseases 2024 Apr;30(3):1583-1590
SOX18 meditates the resistance of Bmi1-expressing cells to cetuximab in HNSCC.
Zhang C, Chen Z, Gao N, Xiong G, Chen P, Li H, Chen D, He Q, Peng L
Oral diseases 2024 Apr;30(3):1100-1113
Oral diseases 2024 Apr;30(3):1100-1113
Ataxin-2 sequesters Raptor into aggregates and impairs cellular mTORC1 signaling.
Liu YJ, Wang JY, Zhang XL, Jiang LL, Hu HY
The FEBS journal 2024 Apr;291(8):1795-1812
The FEBS journal 2024 Apr;291(8):1795-1812
GHITM regulates malignant phenotype and sensitivity to PD-1 blockade of renal cancer cells via Notch signalling.
Huang S, Liu J, Hu J, Hou Y, Hu M, Zhang B, Luo H, Fu S, Chen Y, Liu X, Chen Z, Wang L
Journal of cellular and molecular medicine 2024 Apr;28(8):e18290
Journal of cellular and molecular medicine 2024 Apr;28(8):e18290
CCDC157 is essential for sperm differentiation and shows oligoasthenoteratozoospermia-related mutations in men.
Zheng H, Gong C, Li J, Hou J, Gong X, Zhu X, Deng H, Wu H, Zhang F, Shi Q, Zhou J, Shi B, Yang X, Xi Y
Journal of cellular and molecular medicine 2024 Apr;28(7):e18215
Journal of cellular and molecular medicine 2024 Apr;28(7):e18215
BUB1/KIF14 complex promotes anaplastic thyroid carcinoma progression by inducing chromosome instability.
Jin T, Ding L, Chen J, Zou X, Xu T, Xuan Z, Wang S, Chen J, Wang W, Zhu C, Zhang Y, Huang P, Pan Z, Ge M
Journal of cellular and molecular medicine 2024 Apr;28(7):e18182
Journal of cellular and molecular medicine 2024 Apr;28(7):e18182
Integrating Network Pharmacology and Experimental Validation to Reveal the Mechanism of Vine Grape Tea Polyphenols on Hyperuricemia-Induced Renal Injury in Mice.
Li X, Li B, Meng X, Yu F, Yu X, Zhao W, Wang Y, Gao H, Cheng M, Zhong L
Journal of medicinal food 2024 Apr;27(4):312-329
Journal of medicinal food 2024 Apr;27(4):312-329
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Bao M, Li S, Zhu Y, Dong X, Wang R, Jing F
Experimental and therapeutic medicine 2024 Apr;27(4):165
Experimental and therapeutic medicine 2024 Apr;27(4):165
Paclitaxel mediates the PI3K/AKT/mTOR pathway to reduce proliferation of FLT3‑ITD(+) AML cells and promote apoptosis.
Su Y, Wu M, Zhou B, Bai Z, Pang R, Liu Z, Zhao W
Experimental and therapeutic medicine 2024 Apr;27(4):161
Experimental and therapeutic medicine 2024 Apr;27(4):161
Programmed cell death 4 blocks autophagy and promotes dopaminergic neuronal injury in Parkinson's disease.
Cao G, Kang T, Li N, Li P
Experimental and therapeutic medicine 2024 Apr;27(4):135
Experimental and therapeutic medicine 2024 Apr;27(4):135
Porcine deltacoronavirus NS7a antagonizes JAK/STAT pathway by inhibiting the interferon-stimulated gene factor 3 (ISGF3) formation.
Mou C, Xie S, Zhu L, Cheng Y, Pan S, Zhang C, Chen Z
International journal of biological macromolecules 2024 Apr;264(Pt 2):130693
International journal of biological macromolecules 2024 Apr;264(Pt 2):130693
Tumor cell-derived LC3B(+)extracellular vesicles mediate the crosstalk between tumor microenvironment and immunotherapy efficacy in hepatocellular carcinoma via the HSP90α-IL-6/IL-8 signaling axis.
Chen YQ, Man ZS, Zheng L, Zhang Y, Zhao CW, Ma YT, Zhou J, Wang P, Yu Y, Gu F, Niu GP
Clinical immunology (Orlando, Fla.) 2024 Apr;261:109925
Clinical immunology (Orlando, Fla.) 2024 Apr;261:109925
Longitudinal skeletal growth and growth plate morphological characteristics of chondro-tissue specific CUL7 knockout mice.
Zhang Y, Hu F, Li H, Duan Q, Pi Y, Li Y, Zhang H
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2024 Apr;253:152224
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2024 Apr;253:152224
Effects of Halloysite Nanotubes and Multi-walled Carbon Nanotubes on Kruppel-like Factor 15-Mediated Downstream Events in Mouse Hearts After Intravenous Injection.
Zhang Y, Cheng Y, Zhao W, Song F, Cao Y
Cardiovascular toxicology 2024 Apr;24(4):408-421
Cardiovascular toxicology 2024 Apr;24(4):408-421
PGC-1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons.
Chen N, Zhan RN, Liu DQ, Zhang Y, Tian YK, Zhou YQ
Biochemical pharmacology 2024 Apr;222:116053
Biochemical pharmacology 2024 Apr;222:116053
Icariin attenuates vascular endothelial dysfunction by inhibiting inflammation through GPER/Sirt1/HMGB1 signaling pathway in type 1 diabetic rats.
Yao W, Tao R, Wang K, Ding X
Chinese journal of natural medicines 2024 Apr;22(4):293-306
Chinese journal of natural medicines 2024 Apr;22(4):293-306
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Chen L, Zhao Z, Diarimalala RO, Chen Z, Wang Y, Zhan T, Zhao Y, Ma C, Wang X, Zhao C, Xiao Z, Hu K, Wu P
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Resveratrol Inhibits Zinc Deficiency-Induced Mitophagy and Exerts Cardiac Cytoprotective Effects.
Wang P, Yang Y, Guo J, Ma T, Hu Y, Huang L, He Y, Xi J
Biological trace element research 2024 Apr;202(4):1669-1682
Biological trace element research 2024 Apr;202(4):1669-1682
Exosome-based WTAP siRNA delivery ameliorates myocardial ischemia-reperfusion injury.
Yin T, Wang N, Jia F, Wu Y, Gao L, Zhang J, Hou R
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Apr;197:114218
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Apr;197:114218
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
Wu H, Qu L, Bai X, Zhu C, Liu Y, Duan Z, Liu H, Fu R, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
Arsenic disturbs neural tube closure involving AMPK/PKB-mTORC1-mediated autophagy in mice.
Li X, Li G, Cui S, Hou Y, Li Z, Yan Z, Huang T, Zhao T, Su H, Zhou B, Zhang J, Ao R, Zhao H, Qiu Y, Liu Z, Xie J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114538
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114538
3-Monochloropropane-1,2-diol esters induce HepG2 cells necroptosis via CTSB/TFAM/ROS pathway.
Guan S, Qu X, Wang J, Zhang D, Lu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114525
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114525
Decreased FGF23 inhibits placental angiogenesis via the ERK1/2-EGR-1 signaling pathway in preeclampsia.
Zhao S, Zhou J, Chen R, Zhou W, Geng H, Huang Y, Shi S, Yuan L, Wang Z, Wang D
Cytokine 2024 Apr;176:156508
Cytokine 2024 Apr;176:156508
Oseltamivir enhances 5-FU sensitivity in esophageal squamous carcinoma with high SPNS1.
Yang X, Jiao Y, Zhang Y, Sun M, Gao Y, Zhou Y, Xiao H, Ren J, Zhou Z, Zhai Y, Song B, Zhang L, Kong P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116367
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116367
Icariin alleviates diabetic renal interstitial fibrosis aggravation by inhibiting miR-320a-3p targeting BMP6.
Wang K, Hou M, Qiao C, Duan Y, Tao R, Wang X, Xiao K, Liu S, Zhao H, Wang J, Jia Z, Ding X
Journal of pharmacological sciences 2024 Apr;154(4):316-325
Journal of pharmacological sciences 2024 Apr;154(4):316-325
N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.
Liu J, Dong X, Xie R, Tang Y, Thomas AM, Li S, Liu S, Yu M, Qin H
Placenta 2024 Apr;149:18-28
Placenta 2024 Apr;149:18-28
N6-methyladenosine-modified circTEAD1 stabilizes Yap1 mRNA to promote chordoma tumorigenesis.
Li H, Tang Y, Ruan X, Zhang J, Liu H, Yu S, Chen H, Yang H, Zhang K, Chen K
Clinical and translational medicine 2024 Apr;14(4):e1658
Clinical and translational medicine 2024 Apr;14(4):e1658
Oleanolic acid alleviates obesity-induced skeletal muscle atrophy via the PI3K/Akt signaling pathway.
Sun Y, Wei X, Zhao T, Shi H, Hao X, Wang Y, Zhang H, Yao Z, Zheng M, Ma T, Fu T, Lu J, Luo X, Yan Y, Wang H
FEBS open bio 2024 Apr;14(4):584-597
FEBS open bio 2024 Apr;14(4):584-597
Knocking down GRAMD1C expression reduces 6-OHDA-induced apoptosis in PC12 cells.
He H, Zhang B, Wang X, Chen L
Toxicology research 2024 Apr;13(2):tfae051
Toxicology research 2024 Apr;13(2):tfae051
Rosmarinic acid mitigates acrylamide induced neurotoxicity via suppressing endoplasmic reticulum stress and inflammation in mouse hippocampus.
Wang TB, He Y, Li RC, Yu YX, Liu Y, Qi ZQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155448
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155448
Baohuoside I suppresses the NLRP3 inflammasome activation via targeting GPER to fight against Parkinson's disease.
Gu Y, Hu ZF, Zheng DW, Yang YQ, Dong XL, Chen WF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155435
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155435
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
Tan P, Cai S, Huang Z, Li M, Liu S, Chen J, Fu W, Zhao L
Cellular signalling 2024 Apr;116:111033
Cellular signalling 2024 Apr;116:111033
H(2)S-Releasing Versatile Montmorillonite Nanoformulation Trilogically Renovates the Gut Microenvironment for Inflammatory Bowel Disease Modulation.
Jin T, Lu H, Zhou Q, Chen D, Zeng Y, Shi J, Zhang Y, Wang X, Shen X, Cai X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2308092
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2308092
Effects of 1,4-dihydropyridine derivatives on cell injury and mTOR of HepG2 and 3D-QSAR study.
Liu H, Zhu S, Xia G, Huang Z, Han W, Li Z, Liu C
Computational biology and chemistry 2024 Apr;109:108010
Computational biology and chemistry 2024 Apr;109:108010
Impact of endocrine-active compounds on adrenal androgen production in pigs during neonatal period.
Knapczyk-Stwora K, Kozlowska A, Jastrzabek D, Grzesiak M, Slomczynska M, Koziorowski M
Environmental toxicology and pharmacology 2024 Apr;107:104435
Environmental toxicology and pharmacology 2024 Apr;107:104435
Targeting Mitochondrial Complex I Deficiency in MPP(+)/MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene.
Li H, Zhang J, Shen Y, Ye Y, Jiang Q, Chen L, Sun B, Chen Z, Shen L, Fang H, Yang J, Gu H
Biological procedures online 2024 Apr 9;26(1):9
Biological procedures online 2024 Apr 9;26(1):9
HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer.
Suo D, Gao X, Chen Q, Zeng T, Zhan J, Li G, Zheng Y, Zhu S, Yun J, Guan XY, Li Y
Journal of experimental & clinical cancer research : CR 2024 Apr 8;43(1):106
Journal of experimental & clinical cancer research : CR 2024 Apr 8;43(1):106
ATP Citrate Lyase is a General Tumour Biomarker and Contributes to the Development of Cutaneous Squamous Cell Carcinoma.
Luo R, Huang Y, Bai R, Liu M, Sun L, Wang X, Zheng Y
Acta dermato-venereologica 2024 Apr 8;104:adv23805
Acta dermato-venereologica 2024 Apr 8;104:adv23805
Enhancing Skin Injury Repair: Combined Application of PF-127 Hydrogel and hADSC-Exos Containing miR-148a-3p.
Zhang Q, Su P, Zhao F, Ren H, He C, Wu Q, Wang Z, Ma J, Huang X, Wang Z
ACS biomaterials science & engineering 2024 Apr 8;10(4):2235-2250
ACS biomaterials science & engineering 2024 Apr 8;10(4):2235-2250
NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16.
Guo D, Zhang M, Wei T, Zhang X, Shi X, Tang H, Ding M, Li J, Zhang S, Guo W
Cellular and molecular life sciences : CMLS 2024 Apr 6;81(1):167
Cellular and molecular life sciences : CMLS 2024 Apr 6;81(1):167
Uncovering the key pharmacodynamic material basis and possible molecular mechanism of Xiaoke formulation improve insulin resistant through a comprehensive investigation.
Ma W, Long J, Dong L, Zhang J, Wang A, Zhang Y, Yan D
Journal of ethnopharmacology 2024 Apr 6;323:117752
Journal of ethnopharmacology 2024 Apr 6;323:117752
Guben Qingfei decoction attenuates LPS-induced acute lung injury by modulating the TLR4/NF-κB and Keap1/Nrf2 signaling pathways.
Zeng Z, Fu Y, Li M, Shi Y, Ding Q, Chen S
Journal of ethnopharmacology 2024 Apr 6;323:117674
Journal of ethnopharmacology 2024 Apr 6;323:117674
Protective effects of Huang-Qi-Ge-Gen decoction against diabetic liver injury through regulating PI3K/AKT/Nrf2 pathway and metabolic profiling.
Zhang ZT, Liang QF, Wang X, Wang RS, Duan TT, Wang SM, Tang D
Journal of ethnopharmacology 2024 Apr 6;323:117647
Journal of ethnopharmacology 2024 Apr 6;323:117647
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence.
Wei X, Li Y, Jiang T, Luo P, Dai Y, Wang Q, Xu M, Yan J, Li Y, Gao J, Liu L, Zhang C, Liu Y
European journal of pharmacology 2024 Apr 5;968:176397
European journal of pharmacology 2024 Apr 5;968:176397
Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer.
Gao Z, Zhang N, An B, Li D, Fang Z, Xu D
Cancer cell international 2024 Apr 5;24(1):127
Cancer cell international 2024 Apr 5;24(1):127
Transcranial direct current stimulation promotes angiogenesis and improves neurological function via the OXA-TF-AKT/ERK signaling pathway in traumatic brain injury.
Ren B, Kang J, Wang Y, Meng X, Huang Y, Bai Y, Feng Z
Aging 2024 Apr 5;16(7):6566-6587
Aging 2024 Apr 5;16(7):6566-6587
Proteomic analysis of DEN and CCl(4)-induced hepatocellular carcinoma mouse model.
Zhang Q, Liu Y, Ren L, Li J, Lin W, Lou L, Wang M, Li C, Jiang Y
Scientific reports 2024 Apr 5;14(1):8013
Scientific reports 2024 Apr 5;14(1):8013
Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans.
Guo B, Sun Y, Wang Y, Zhang Y, Zheng Y, Xu S, Yang G, Ren W
BMC genomics 2024 Apr 4;25(1):339
BMC genomics 2024 Apr 4;25(1):339
Pyrotinib is effective in both trastuzumab-sensitive and primary resistant HER2-positive breast tumors.
Zhang J, Yin G, Ye C, Feng M, Ji C, Zhou W, Wang F, Yu L, Huang S, Yu Z
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2024 Apr 30;36(2):124-137
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2024 Apr 30;36(2):124-137
Nitro-oleic acid (NO(2)-OA) ameliorates erectile dysfunction in a rat model of diabetes mellitus via modulation of fibrosis, inflammation and autophagy.
Zhao C, Chen W, Gong F, Wang W, Fan C, Li Y, Lan T, Wang W, Yuan M
Translational andrology and urology 2024 Apr 30;13(4):537-547
Translational andrology and urology 2024 Apr 30;13(4):537-547
DNMT3A promotes glioma growth and malignancy via TNF-α/NF-κB signaling pathway.
Su X, Liu J, Tu Z, Ji Q, Li J, Liu F
Translational cancer research 2024 Apr 30;13(4):1786-1806
Translational cancer research 2024 Apr 30;13(4):1786-1806
RBM39 is a potential prognostic biomarker with functional significance in hepatocellular carcinoma.
Cui F, Wang W, Zhuang C, He D, Wang P
Translational cancer research 2024 Apr 30;13(4):1606-1622
Translational cancer research 2024 Apr 30;13(4):1606-1622
Mesothelin promotes brain metastasis of non-small cell lung cancer by activating MET.
Xia S, Duan W, Xu M, Li M, Tang M, Wei S, Lin M, Li E, Liu W, Wang Q
Journal of experimental & clinical cancer research : CR 2024 Apr 3;43(1):103
Journal of experimental & clinical cancer research : CR 2024 Apr 3;43(1):103
Electroacupuncture promotes macrophage/microglial M2 polarization and suppresses inflammatory pain through AMPK.
Nan FB, Gu YX, Wang JL, Chen SD
Neuroreport 2024 Apr 3;35(6):343-351
Neuroreport 2024 Apr 3;35(6):343-351
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
Yang L, Ruan Y, Xu H
BMC cancer 2024 Apr 29;24(1):544
BMC cancer 2024 Apr 29;24(1):544
Comparative Analysis of Site-Specific N-glycosylation of LAMP1 from Breast Cancer Tissues.
Ohashi S, Takakura D, Kobayashi N, Tokuhisa M, Ichikawa Y, Kawasaki N
Journal of biochemistry 2024 Apr 29;175(5):561-572
Journal of biochemistry 2024 Apr 29;175(5):561-572
Cetuximab-Toxin Conjugate and NPe6 with Light Enhanced Cytotoxic Effects in Head and Neck Squamous Cell Carcinoma In Vitro.
Komatsu N, Kosai A, Kuroda M, Hamakubo T, Abe T
Biomedicines 2024 Apr 29;12(5)
Biomedicines 2024 Apr 29;12(5)
Induction of IFIT1/IFIT3 and inhibition of Bcl-2 orchestrate the treatment of myeloma and leukemia via pyroptosis.
He Y, Jiang S, Cui Y, Liang J, Zhong Y, Sun Y, Moran MF, Huang Z, He G, Mao X
Cancer letters 2024 Apr 28;588:216797
Cancer letters 2024 Apr 28;588:216797
SYVN1 modulates papillary thyroid carcinoma progression by destabilizing HMGB1.
Duan F, Kong F, Jiang T, Liu H
Cell division 2024 Apr 28;19(1):15
Cell division 2024 Apr 28;19(1):15
Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats.
Wang X, Fu Y, Yang X, Chen Y, Zeng N, Hu S, Ouyang S, Pan X, Wu S
Scientific reports 2024 Apr 27;14(1):9723
Scientific reports 2024 Apr 27;14(1):9723
CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway.
Gao W, Liu R, Huang K, Fu W, Wang A, Du G, Tang H, Yin L, Yin ZS
Molecular medicine (Cambridge, Mass.) 2024 Apr 25;30(1):55
Molecular medicine (Cambridge, Mass.) 2024 Apr 25;30(1):55
Mechanism of ameliorating cerebral ischemia/reperfusion injury by antioxidant inhibition of autophagy based on network pharmacology and experimental verification.
Zheng Y, Huang Z, Zhao Y, Huang L, Wang J, Li H, Chen X, Wang J, Xie J
Aging 2024 Apr 25;16(8):7474-7486
Aging 2024 Apr 25;16(8):7474-7486
Network pharmacology and experimental validation of effects of total saponins extracted from Abrus cantoniensis Hance on acetaminophen-induced liver injury.
He J, Chen L, Wang P, Cen B, Li J, Wei Y, Yao X, Xu Z
Journal of ethnopharmacology 2024 Apr 24;324:117740
Journal of ethnopharmacology 2024 Apr 24;324:117740
Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation.
Zhi Y, Zhao X, Liu Z, Shen G, Zhang T, Zhang T, Hu G
Molecules (Basel, Switzerland) 2024 Apr 24;29(9)
Molecules (Basel, Switzerland) 2024 Apr 24;29(9)
GFRA4 improves the neurogenic potential of enteric neural crest stem cells via hedgehog pathway.
Zhang F, Cui M, Zhang L, Ma B, Guo F, Wang G
Pediatric research 2024 Apr 24;
Pediatric research 2024 Apr 24;
hnRNPU is required for spermatogonial stem cell pool establishment in mice.
Wen Y, Zhou S, Gui Y, Li Z, Yin L, Xu W, Feng S, Ma X, Gan S, Xiong M, Dong J, Cheng K, Wang X, Yuan S
Cell reports 2024 Apr 23;43(4):114113
Cell reports 2024 Apr 23;43(4):114113
25-hydroxycholesterol promotes proliferation and metastasis of lung adenocarcinoma cells by regulating ERβ/TNFRSF17 axis.
He M, Jiang W, Li X, Liu H, Ren H, Lin Y
BMC cancer 2024 Apr 22;24(1):505
BMC cancer 2024 Apr 22;24(1):505
Intersectin1 promotes clathrin-mediated endocytosis by organizing and stabilizing endocytic protein interaction networks.
Jin M, Iwamoto Y, Shirazinejad C, Drubin DG
bioRxiv : the preprint server for biology 2024 Apr 22;
bioRxiv : the preprint server for biology 2024 Apr 22;
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
Wu M, Huang X, Wu B, Zhu M, Zhu Y, Yu L, Lan T, Liu J
Molecular biology reports 2024 Apr 20;51(1):553
Molecular biology reports 2024 Apr 20;51(1):553
FTO promotes gastric cancer progression by modulating MAP4K4 expression via demethylation in an m6A-dependent manner.
Yin Z, Guo X, Liang X, Wang Z
Medical oncology (Northwood, London, England) 2024 Apr 20;41(5):120
Medical oncology (Northwood, London, England) 2024 Apr 20;41(5):120
Unraveling the interplay of ferroptosis and immune dysregulation in diabetic kidney disease: a comprehensive molecular analysis.
Jiao Y, Liu X, Shi J, An J, Yu T, Zou G, Li W, Zhuo L
Diabetology & metabolic syndrome 2024 Apr 20;16(1):86
Diabetology & metabolic syndrome 2024 Apr 20;16(1):86
Esculin targets TLR4 to protect against LPS-induced septic cardiomyopathy.
Su Z, Gao M, Weng L, Xu T
International immunopharmacology 2024 Apr 20;131:111897
International immunopharmacology 2024 Apr 20;131:111897
MGP(+) and IDO1(+) tumor-associated macrophages facilitate immunoresistance in breast cancer revealed by single-cell RNA sequencing.
Chang K, Jiao Y, Zhang B, Hou L, He X, Wang D, Li D, Li R, Wang Z, Fan P, Zhang J
International immunopharmacology 2024 Apr 20;131:111818
International immunopharmacology 2024 Apr 20;131:111818
The coumarin component isofraxidin targets the G-protein-coupled receptor S1PR1 to modulate IL-17 signaling and alleviate ulcerative colitis.
Huang Y, Chen X, Liu X, Lin C, Wang Y
International immunopharmacology 2024 Apr 20;131:111814
International immunopharmacology 2024 Apr 20;131:111814
Physalin H ameliorates LPS-induced acute lung injury via KEAP1/NRF2 axis.
Cai Y, Zhu J, Zhu L, Hong L, Zhang J, Kong L, Chen C, Luo J
International immunopharmacology 2024 Apr 20;131:111789
International immunopharmacology 2024 Apr 20;131:111789
Ketogenic diet ameliorates high-fat diet-induced insulin resistance in mouse skeletal muscle by alleviating endoplasmic reticulum stress.
Ma Q, Jiang L, You Y, Ni H, Ma L, Lin X, Wang Z, Yan W, Xiao X, Li X, Li J
Biochemical and biophysical research communications 2024 Apr 2;702:149559
Biochemical and biophysical research communications 2024 Apr 2;702:149559
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
Fan B, Lin J, Luo Q, Liao W, Hao C
Neurotoxicity research 2024 Apr 2;42(2):22
Neurotoxicity research 2024 Apr 2;42(2):22
Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5.
Lai Y, Gao Y, Lin J, Liu F, Yang L, Zhou J, Xue Y, Li Y, Chang Z, Li J, Chao T, Chen J, Cheng X, Gao X, Li X, Lu F, Chu Q, Wang W
Cell metabolism 2024 Apr 2;36(4):822-838.e8
Cell metabolism 2024 Apr 2;36(4):822-838.e8
CCNA2 and KIF23 are molecular targets for the prognosis of adenoid cystic carcinoma.
Di Y, Zhang H, Zhang B, Li T, Li D
Aging 2024 Apr 2;16
Aging 2024 Apr 2;16
Urolithin B reduces cartilage degeneration and alleviates osteoarthritis by inhibiting inflammation.
Xue H, Zhou H, Lou Q, Yuan P, Feng Z, Qiao L, Zhang J, Xie H, Shen Y, Ma Q, Wang S, Zhang B, Ye H, Cheng J, Sun X, Shi P
Food & function 2024 Apr 2;15(7):3552-3565
Food & function 2024 Apr 2;15(7):3552-3565
Islet-resident macrophage-derived miR-155 promotes β cell decompensation via targeting PDX1.
Zhang Y, Cong R, Lv T, Liu K, Chang X, Li Y, Han X, Zhu Y
iScience 2024 Apr 19;27(4):109540
iScience 2024 Apr 19;27(4):109540
A prognostic and immune related risk model based on zinc homeostasis in hepatocellular carcinoma.
Shi Y, Ye R, Gao Y, Xia F, Yu XF
iScience 2024 Apr 19;27(4):109389
iScience 2024 Apr 19;27(4):109389
A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice.
Ma X, Yin J, Qiao L, Wan H, Liu X, Zhou Y, Wu J, Niu L, Wu M, Wang X, Ye H
Molecular cell 2024 Apr 18;84(8):1585-1600.e7
Molecular cell 2024 Apr 18;84(8):1585-1600.e7
Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling.
Huang W, Yang S, Deng M, Luo R, Liang H, Shen Y, Yang B, Xu C, Hou Y
Functional & integrative genomics 2024 Apr 18;24(3):77
Functional & integrative genomics 2024 Apr 18;24(3):77
Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice.
Chu R, Lu Y, Fan X, Lai C, Li J, Yang R, Xiang Z, Han C, Tian M, Yuan H
Journal of integrative neuroscience 2024 Apr 18;23(4):82
Journal of integrative neuroscience 2024 Apr 18;23(4):82
Biochemical analysis of the host factor activity of ZCCHC14 in hepatitis A virus replication.
Li Y, Lemon SM
Journal of virology 2024 Apr 16;98(4):e0005724
Journal of virology 2024 Apr 16;98(4):e0005724
PEI, a new transfection method, augments the inhibitory effect of RBM5 on prostate cancer.
Zhou X, Cao Y, Li R, Di X, Wang Y, Wang K
Biochemical and biophysical research communications 2024 Apr 16;704:149703
Biochemical and biophysical research communications 2024 Apr 16;704:149703
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
Ma Y, Chen H, Li H, Zheng M, Zuo X, Wang W, Wang S, Lu Y, Wang J, Li Y, Wang J, Qiu M
Cell reports. Medicine 2024 Apr 16;5(4):101488
Cell reports. Medicine 2024 Apr 16;5(4):101488
Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake.
Cheng Y, Zhu Y, Liu Y, Liu X, Ding Y, Li D, Zhang X, Liu Y
International journal of oral science 2024 Apr 16;16(1):31
International journal of oral science 2024 Apr 16;16(1):31
Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice.
Zheng Z, Gao W, Zhu Z, Li S, Chen X, Cravotto G, Sui Y, Zhou L
Antioxidants (Basel, Switzerland) 2024 Apr 16;13(4)
Antioxidants (Basel, Switzerland) 2024 Apr 16;13(4)
JMJD3 activation contributes to renal protection and regeneration following acute kidney injury in mice.
Yu C, Tang J, Yu J, Wang Y, Liu N, Dong Z, Zhuang S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23583
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23583
Preliminary investigation into the impact of BPA on osteoblast activity and bone development: In vitro and in vivo models.
Shi X, Wu K, Liu C, Cao K, Zhang Q, Wu W, Luo C, Huang W
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123731
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123731
Phthalate exposure aggravates periodontitis by activating NFκB pathway.
Wu W, Jiang W, Zhou Y, Zhang Z, Li G, Tang C
Ecotoxicology and environmental safety 2024 Apr 15;275:116252
Ecotoxicology and environmental safety 2024 Apr 15;275:116252
Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction.
Lin Z, Liu C, Yan Z, Cheng J, Wang X, Zhou F, Lyu X, Zhang S, Zhang D, Meng X, Zhao Y
European journal of medicinal chemistry 2024 Apr 15;270:116366
European journal of medicinal chemistry 2024 Apr 15;270:116366
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
Wang Y, Gu L, Li J, Wang R, Zhuang Y, Li X, Wang X, Zhang J, Liu Q, Wang J, Song SJ
European journal of medicinal chemistry 2024 Apr 15;270:116312
European journal of medicinal chemistry 2024 Apr 15;270:116312
A mutation in LPAR2 activates the miR-939-5p-LPAR2-PI3K/AKT axis to regulate the proliferation and apoptosis of granulosa cells in sheep.
Zhang R, Liu Y, Li W, Wang P, Liu Z, Wen Y, Chu M, Wang L
Theriogenology 2024 Apr 15;219:1-10
Theriogenology 2024 Apr 15;219:1-10
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Peng Z, Ding YN, Yang ZM, Li XJ, Zhuang Z, Lu Y, Tang QS, Hang CH, Li W
Acta biomaterialia 2024 Apr 15;179:325-339
Acta biomaterialia 2024 Apr 15;179:325-339
Live Cell Monitoring of Separase Activity, a Key Enzymatic Reaction for Chromosome Segregation, with Chimeric FRET-Based Molecular Sensor upon Cell Cycle Progression.
Rahman MS, Shindo Y, Oka K, Ikeda W, Suzuki M
Biosensors 2024 Apr 15;14(4)
Biosensors 2024 Apr 15;14(4)
Artesunate induces ferroptosis by regulating MT1G and has an additive effect with doxorubicin in diffuse large B-cell lymphoma cells.
Xiong D, Geng C, Zeng L, Yao H, Tan J, Zhang L, Liu X, Liu L
Heliyon 2024 Apr 15;10(7):e28584
Heliyon 2024 Apr 15;10(7):e28584
Endothelin-1-mediated Brainstem Glial Activation Produces Asthmatic Airway Vagal Hypertonia Via Enhanced ATP-P2X4 Receptor Signaling in Sprague-Dawley Rats.
Lin Y, Liu T, Chen H, Zeng M, Hu S, Yu X, Chen Y, Xia C, Wang J, Wang J
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Apr 13;19(1):13
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Apr 13;19(1):13
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase.
Zhang T, Zhao F, Li J, Sun X, Zhang X, Wang H, Fan P, Lai L, Li Z, Sui T
Nucleic acids research 2024 Apr 12;52(6):2776-2791
Nucleic acids research 2024 Apr 12;52(6):2776-2791
Tyrosine hydroxylase inhibits HCC progression by downregulating TGFβ/Smad signaling.
Liu G, Li M, Zeng Z, Fan Q, Ren X, Wang Z, Sun Y, He Y, Sun L, Deng Y, Liu S, Zhong C, Gao J
European journal of medical research 2024 Apr 12;29(1):228
European journal of medical research 2024 Apr 12;29(1):228
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology.
Lin K, Xia B, Wang X, He X, Zhou M, Lin Y, Qiao Y, Li R, Chen Q, Li Y, Feng J, Chen T, Chen C, Li X, Zhang H, Lu L, Liu B, Zhang X
Journal of translational medicine 2024 Apr 12;22(1):349
Journal of translational medicine 2024 Apr 12;22(1):349
Zyxin is important for the stability and function of podocytes, especially during mechanical stretch.
Kliewe F, Siegerist F, Hammer E, Al-Hasani J, Amling TRJ, Hollemann JZE, Schindler M, Drenic V, Simm S, Amann K, Daniel C, Lindenmeyer M, Hecker M, Völker U, Endlich N
Communications biology 2024 Apr 11;7(1):446
Communications biology 2024 Apr 11;7(1):446
Design, Synthesis, and Activity Evaluation of Fluorine-Containing Scopolamine Analogues as Potential Antidepressants.
Wang L, Zhu X, Wang B, Wang Y, Wang M, Yang S, Su C, Chang J, Zhu B
Journal of medicinal chemistry 2024 Apr 11;67(7):5391-5420
Journal of medicinal chemistry 2024 Apr 11;67(7):5391-5420
METTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis.
Ouyang P, Li K, Xu W, Chen C, Shi Y, Tian Y, Gong J, Bao Z
Journal of experimental & clinical cancer research : CR 2024 Apr 11;43(1):111
Journal of experimental & clinical cancer research : CR 2024 Apr 11;43(1):111
Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression.
Pan R, Wang R, Cheng F, Wang L, Cui Z, She J, Yang X
Reproductive biology and endocrinology : RB&E 2024 Apr 11;22(1):41
Reproductive biology and endocrinology : RB&E 2024 Apr 11;22(1):41
Galangin Prevents Against Ethanol-Induced Intestinal Barrier Dysfunction and NLRP3 Inflammasome Activation via NF-κB/MAPK Signaling Pathways in Mice and Caco-2 Cells.
Zhao Y, Li B, Liu J, Chen L, Teng H
Journal of agricultural and food chemistry 2024 Apr 11;
Journal of agricultural and food chemistry 2024 Apr 11;
In Vitro Comparative Analysis of the Effect and Structure-Based Influencing Factors of Flavonols on Lipid Accumulation.
Ang B, Yang T, Wang Z, Cheng Y, Chen Q, Wang Z, Zeng M, Chen J, He Z
Journal of agricultural and food chemistry 2024 Apr 10;72(14):8237-8246
Journal of agricultural and food chemistry 2024 Apr 10;72(14):8237-8246
DHCR24 Insufficiency Promotes Vascular Endothelial Cell Senescence and Endothelial Dysfunction via Inhibition of Caveolin-1/ERK Signaling.
Li H, Yang Z, Liang W, Nie H, Guan Y, Yang N, Ji T, Liu Y, Huang Y, Zhang L, Yan J, Zhang C
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Apr 1;79(4)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Apr 1;79(4)
Identification of Novel FZD4 Mutations in Familial Exudative Vitreoretinopathy and Investigating the Pathogenic Mechanisms of FZD4 Mutations.
Dai E, Liu M, Li S, Zhang X, Wang S, Zhao R, He Y, Peng L, Lv L, Xiao H, Yang M, Yang Z, Zhao P
Investigative ophthalmology & visual science 2024 Apr 1;65(4):1
Investigative ophthalmology & visual science 2024 Apr 1;65(4):1
Up-regulation of RAN by MYBL2 maintains osteosarcoma cancer stem-like cells population during heterogeneous tumor generation.
Gao W, Zhou J, Huang J, Zhang Z, Chen W, Zhang R, Kang T, Liao D, Zhong L
Cancer letters 2024 Apr 1;586:216708
Cancer letters 2024 Apr 1;586:216708
Renalase mediates macrophage-to-fibroblast crosstalk to attenuate pressure overload-induced pathological myocardial fibrosis.
Fu R, You N, Li R, Zhao X, Li Y, Li X, Jiang W
Journal of hypertension 2024 Apr 1;42(4):629-643
Journal of hypertension 2024 Apr 1;42(4):629-643
Protective role of forsythoside B in Kawasaki disease-induced cardiac injury: Inhibition of pyroptosis via the SIRT1-NF-κB-p65 signaling pathway.
Yang Y, Wang N, Wang Z, Zhao M, Chen L, Shi Z
Chemico-biological interactions 2024 Apr 1;392:110953
Chemico-biological interactions 2024 Apr 1;392:110953
KRAS Mutation Detection with (2S,4R)-4-[(18)F]FGln for Noninvasive PDAC Diagnosis.
Liu S, Liu F, Hou X, Zhang Q, Ren Y, Zhu H, Yang Z, Xu X
Molecular pharmaceutics 2024 Apr 1;21(4):2034-2042
Molecular pharmaceutics 2024 Apr 1;21(4):2034-2042
Bone marrow-derived mesenchymal stem cell-conditioned medium ameliorates diabetic foot ulcers in rats.
Xu YF, Wu YX, Wang HM, Gao CH, Xu YY, Yan Y
Clinics (Sao Paulo, Brazil) 2023;78:100181
Clinics (Sao Paulo, Brazil) 2023;78:100181
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Zhang T, Cao W, Sun H, Yu D, Zhong C
Nutrition and cancer 2023;75(3):971-979
Nutrition and cancer 2023;75(3):971-979
Ellagic acid alleviates TNBS-induced intestinal barrier dysfunction by regulating mucin secretion and maintaining tight junction integrity in rats.
Peng B, Xue L, Yu Q, Zhong T
International journal of food sciences and nutrition 2023;74(4):476-486
International journal of food sciences and nutrition 2023;74(4):476-486
Harnessing nanobodies for target protein degradation through the Affinity-directed PROtein Missile (AdPROM) system.
Carton B, Röth S, Macartney TJ, Sapkota GP
Methods in enzymology 2023;681:61-79
Methods in enzymology 2023;681:61-79
The PPARα/CYP4A14 bile acid pathway is associated with lipid metabolism disorders caused by low birth weight with high-fat diet.
Zhou F, Yang L, Sun W, Wang X, Guo N, Ma H, Yang L
Food & nutrition research 2023;67
Food & nutrition research 2023;67
The role of miR-369-3p in proliferation and differentiation of preadipocytes in Aohan fine-wool sheep.
Xue S, Liu K, Zhao L, Zhou L, Gao X, Liu L, Liu N, He J
Archives animal breeding 2023;66(1):93-102
Archives animal breeding 2023;66(1):93-102
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Shi G, Zeng L, Shi J, Chen Y
International heart journal 2023;64(3):462-469
International heart journal 2023;64(3):462-469
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Chang W, Li Y, Liu F, Zang K, Zhang P, Qu S, Zhao J, Xue J
Journal of vascular research 2023;60(4):234-244
Journal of vascular research 2023;60(4):234-244
Hepatocellular SETDB1 Regulates Hepatic Ischemia-Reperfusion Injury through Targeting Lysine Methylation of ASK1 Signal.
Xia K, Wang T, Chen Z, Guo J, Yu B, Chen Q, Qiu T, Zhou J, Zheng S
Research (Washington, D.C.) 2023;6:0256
Research (Washington, D.C.) 2023;6:0256
Preclinical study of LMP1-RNAi-based anti-tumor therapy in EBV-positive nasopharyngeal carcinoma.
Yuan Q, Chen BH, Huang DJ, Zhang R
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2023;56:e12638
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2023;56:e12638
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
Feng Q, Yang Y, Qiao Y, Zheng Y, Yu X, Liu F, Wang H, Zheng B, Pan S, Ren K, Liu D, Liu Z
The American journal of Chinese medicine 2023;51(4):997-1018
The American journal of Chinese medicine 2023;51(4):997-1018
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
Li Q, Li Z, Liu C, Xu M, Li T, Wang Y, Feng J, Yin X, Du X, Lu C
The American journal of Chinese medicine 2023;51(4):929-951
The American journal of Chinese medicine 2023;51(4):929-951
Tetrandrine Inhibits Cancer Stem Cell Characteristics and Epithelial to Mesenchymal Transition in Triple-Negative Breast Cancer via SOD1/ROS Signaling Pathway.
Liu T, Li K, Zhang Z, Peng J, Yang J, Law BYK, Liu X, Li W
The American journal of Chinese medicine 2023;51(2):425-444
The American journal of Chinese medicine 2023;51(2):425-444
Oxidative stress and cellular toxicity induced by dihydropyrazine: a comparative study with other Maillard reaction products.
Miyauchi Y, Koba H, Sawai M, Kansui H, Takechi S
The Journal of toxicological sciences 2023;48(5):263-272
The Journal of toxicological sciences 2023;48(5):263-272
A Complex of Type I Platelet-Activating Factor Acetylhydrolase (PAF-AH) Catalytic Subunits Switches from α1/α2 Heterodimer to α2/α2 Homodimer during Adipocyte Differentiation of 3T3-L1 Cells.
Nakamura Y, Kihara-Negishi F, Tanigawa K, Kiriya M, Kadowaki Y, Imagawa H, Nakanishi H, Watanabe S, Maruyama K, Karasawa K
Biological & pharmaceutical bulletin 2023;46(2):257-262
Biological & pharmaceutical bulletin 2023;46(2):257-262
Exosomal miR-133a-3p promotes the growth and metastasis of lung cancer cells following incomplete microwave ablation.
Yang X, Yu F, Huang G, Ni Y, Zhang T, Zou Z, Meng M
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2023;40(1):2190065
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2023;40(1):2190065
HMGB1 released from dead tumor cells after insufficient radiofrequency ablation promotes progression of HCC residual tumor via ERK1/2 pathway.
Zhou Y, Liu X, Zhang W, Xu Y, Zhang Q, Xiong S, Tang H, Luo B
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2023;40(1):2174709
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2023;40(1):2174709
Immunological function and prognostic value of lymphoid-specific helicase in liver hepatocellular carcinoma.
Fang Y, Tang W, Zhao D, Zhang X, Li N, Yang Y, Jin L, Li Z, Wei B, Miao Y, Zeng Z, Huang H
Cancer biomarkers : section A of Disease markers 2023;38(2):225-239
Cancer biomarkers : section A of Disease markers 2023;38(2):225-239
FKBP11 upregulation promotes proliferation and migration in hepatocellular carcinoma.
Thokerunga E, Huang F, Bongolo CC, Rugera SP, Akankwatsa G, Tu JC
Cancer biomarkers : section A of Disease markers 2023;37(2):109-120
Cancer biomarkers : section A of Disease markers 2023;37(2):109-120
Apolipoprotein C1 promotes tumor progression in gastric cancer.
Gu Q, Zhan T, Guan X, Lai C, Lu NA, Wang G, Xu L, Gao X, Zhang J
Oncology research 2023;31(3):287-297
Oncology research 2023;31(3):287-297
Sulforaphane inhibits TGF-β-induced fibrogenesis and inflammation in human Tenon's fibroblasts.
Liu Y, Huang Y, Guo Z, Yang C, Li Y, Li B, Liu Y, Zheng H
Molecular vision 2023;29:306-316
Molecular vision 2023;29:306-316
The impacts of resveratrol on the retinal degeneration in a rat model of retinitis pigmentosa induced by alkylation: an in-vivo study.
Yan W, Sun Y, Wang Y, Liang W, Xia Y, Yan W, Chen M, Chen T, Li D
Animal cells and systems 2023;27(1):138-148
Animal cells and systems 2023;27(1):138-148
Indirubin alleviates CCl(4)-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways.
Li X, Yao Y, Wei L
Iranian journal of basic medical sciences 2023;26(9):1047-1052
Iranian journal of basic medical sciences 2023;26(9):1047-1052
Static Magnetic Field Promotes Proliferation, Migration, Differentiation, and AKT Activation of Periodontal Ligament Stem Cells.
Zhang K, Ge W, Luo S, Zhou Z, Liu Y
Cells, tissues, organs 2023;212(4):317-326
Cells, tissues, organs 2023;212(4):317-326
MiR-216a reduces apoptosis of pulmonary microvascular endothelial cells in COPD by targeting DNMT1.
Lin L, Song Q, Cheng W, Liu C, Zhou A, Zhou Z, Chen P
Tobacco induced diseases 2023;21:130
Tobacco induced diseases 2023;21:130
TRIM6 Reduces Ferroptosis and Chemosensitivity by Targeting SLC1A5 in Lung Cancer.
Zhang Y, Dong P, Liu N, Yang JY, Wang HM, Geng Q
Oxidative medicine and cellular longevity 2023;2023:9808100
Oxidative medicine and cellular longevity 2023;2023:9808100
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Wen J, Tang B, Guo L, Chen W, Tang X
International journal of hypertension 2023;2023:9497716
International journal of hypertension 2023;2023:9497716
Identification of a Five Immune Term Signature for Prognosis and Therapy Options (Immunotherapy versus Targeted Therapy) for Patients with Hepatocellular Carcinoma.
Bin X, Luo Z, Wang J, Zhou S
Computational and mathematical methods in medicine 2023;2023:8958962
Computational and mathematical methods in medicine 2023;2023:8958962
Long Noncoding RNA SAMMSON Promotes Melanoma Progression by Inhibiting FOXA2 Expression.
Yang L, Zhou M, Wang S, Yi X, Xiong G, Cheng J, Sai B, Zhang Q, Yang Z, Kuang Y, Zhu Y
Stem cells international 2023;2023:8934210
Stem cells international 2023;2023:8934210
miR-135a Regulates Atrial Fibrillation by Targeting Smad3.
Fan X, Feng K, Liu Y, Yang L, Zhao Y, Tian L, Tang Y, Wang X
Cardiovascular therapeutics 2023;2023:8811996
Cardiovascular therapeutics 2023;2023:8811996
hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.
Tang Y, Si Y, Liu C, Li C, Qu L, Liu Y, Fu Q, Luo Q
Stem cells international 2023;2023:8014052
Stem cells international 2023;2023:8014052
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Chi B, Zou A, Mao L, Cai D, Xiao T, Wang Y, Wang Q, Ji Y, Sun L
Oxidative medicine and cellular longevity 2023;2023:7747727
Oxidative medicine and cellular longevity 2023;2023:7747727
Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells.
Niu H, Li J, Liang H, Wu G, Chen M
Cardiology research and practice 2023;2023:7296874
Cardiology research and practice 2023;2023:7296874
Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction.
Yang Q, Nie Z, Zhu Y, Hao M, Liu S, Ding X, Wang F, Wang F, Geng X
Oxidative medicine and cellular longevity 2023;2023:6897268
Oxidative medicine and cellular longevity 2023;2023:6897268
Huoxiang Zhengqi Oral Liquid Attenuates LPS-Induced Acute Lung Injury by Modulating Short-Chain Fatty Acid Levels and TLR4/NF-κB p65 Pathway.
Tang R, Zhang J, Zhang R, Li X, Lv R, Nan H, Liu J, Zhao Z, He W, Wang L
BioMed research international 2023;2023:6183551
BioMed research international 2023;2023:6183551
GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells.
Ning J, Ding J, Wang S, Jiang Y, Wang D, Jiang S
Journal of immunology research 2023;2023:5532617
Journal of immunology research 2023;2023:5532617
Enriched Environment Attenuates Ferroptosis after Cerebral Ischemia/Reperfusion Injury via the HIF-1α-ACSL4 Pathway.
Liu J, Luo Q, Ke J, Zhang D, Xu Y, Liao W, Chen X, Zhang X
Oxidative medicine and cellular longevity 2023;2023:5157417
Oxidative medicine and cellular longevity 2023;2023:5157417
lncRNA MEG3 Promotes PDK4/GSK-3β/β-Catenin Axis in MEFs by Targeting miR-532-5p.
Yang YY, Deng YX, Yao XT, Luo HH, He WG, Cao XL, Chen RC, He BC, Jiang HT, Wang J
Oxidative medicine and cellular longevity 2023;2023:3563663
Oxidative medicine and cellular longevity 2023;2023:3563663
Effects of Fibulin-5 Gene Silencing on Proliferation and Apoptosis of IgG4-ROD Lacrimal Gland Fibroblasts.
Wu H, Lei D, Zhang X, Wang M, Wang Y, Xia J, Chen F, Chen B, Tian Y
Stem cells international 2023;2023:2742839
Stem cells international 2023;2023:2742839
Study on the Mechanism of Jiaotai Pill Intervention on Insomnia Animal Model Based on Gut Microbiome and Metabolomics.
Yang Y, Liu J, Ou H, Ma X, Li J, Shao B, Jin R, Zhao J
Evidence-based complementary and alternative medicine : eCAM 2023;2023:2442505
Evidence-based complementary and alternative medicine : eCAM 2023;2023:2442505
HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model.
He YF, Hu XM, Khan MA, Yu BY, Sheng YC, Xiao XZ, Wan XX, Tan SP, Xiong K
Mediators of inflammation 2023;2023:2252255
Mediators of inflammation 2023;2023:2252255
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Zou R, Wang S, Cai H, Wang Y, Wang C
Cardiovascular therapeutics 2023;2023:2108584
Cardiovascular therapeutics 2023;2023:2108584
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Liu Z, Fan Z, Wang R, Li X, Chen H, Wang J
Mediators of inflammation 2023;2023:1699946
Mediators of inflammation 2023;2023:1699946
Circular RNA_HIPK3-Targeting miR-93-5p Regulates KLF9 Expression Level to Control Acute Kidney Injury.
Zhengbiao Z, Liang C, Zhi Z, Youmin P
Computational and mathematical methods in medicine 2023;2023:1318817
Computational and mathematical methods in medicine 2023;2023:1318817
STARD12/14 are diagnostic and prognostic biomarkers of lung adenocarcinoma associated with epigenetic regulation, immune infiltration and ferroptosis.
Zhang WD, Hu DM, Shi ZE, Wang QX, Zhang MY, Liu JY, Ji XL, Qu YQ
International journal of medical sciences 2023;20(11):1427-1447
International journal of medical sciences 2023;20(11):1427-1447
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
Frontiers in chemical biology 2023;2
Frontiers in chemical biology 2023;2
TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.
Sun Y, Lin P, Zhou X, Ren Y, He Y, Liang J, Zhu Z, Xu X, Mao X
International journal of biological sciences 2023;19(9):2803-2816
International journal of biological sciences 2023;19(9):2803-2816
LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2.
Liu SS, Li JS, Xue M, Wu WJ, Li X, Chen W
International journal of biological sciences 2023;19(8):2599-2612
International journal of biological sciences 2023;19(8):2599-2612
Tectorigenin targets PKACα to promote GLUT4 expression in skeletal muscle and improve insulin resistance in vitro and in vivo.
Yao X, Liu L, Shao W, Bai M, Ding X, Wang G, Wang S, Zheng L, Sun Y, Wang G, Huang Y, Yu C, Song Z, Bao Y, Yang S, Sun L
International journal of biological sciences 2023;19(5):1579-1596
International journal of biological sciences 2023;19(5):1579-1596
TNFR2 deficiency impairs the growth of mouse colon cancer.
Li P, Yang Y, Yang X, Wang Y, Chou CK, Jiang M, Zheng J, Chen F, Chen X
International journal of biological sciences 2023;19(4):1024-1035
International journal of biological sciences 2023;19(4):1024-1035
Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation.
Chen MM, Guo W, Chen SM, Guo XZ, Xu L, Ma XY, Wang YX, Xie C, Meng LH
International journal of biological sciences 2023;19(3):772-788
International journal of biological sciences 2023;19(3):772-788
BGN/FAP/STAT3 positive feedback loop mediated mutual interaction between tumor cells and mesothelial cells contributes to peritoneal metastasis of gastric cancer.
Wu H, Xiang Z, Huang G, He Q, Song J, Dou R, Yang C, Wang S, Xiong B
International journal of biological sciences 2023;19(2):465-483
International journal of biological sciences 2023;19(2):465-483
XPOT Disruption Suppresses TNBC Growth through Inhibition of Specific tRNA Nuclear Exportation and TTC19 Expression to Induce Cytokinesis Failure.
Dai H, Yang X, Sheng X, Wang Y, Zhang S, Zhang X, Hu L, Zhang Z, Dong X, Yin W, Yao L, Lu J
International journal of biological sciences 2023;19(16):5319-5336
International journal of biological sciences 2023;19(16):5319-5336
Polyphyllin VII induces CTC anoikis to inhibit lung cancer metastasis through EGFR pathway regulation.
Que Z, Luo B, Yu P, Qi D, Shangguan W, Wang P, Liu J, Li Y, Li H, Ke R, Wu E, Tian J
International journal of biological sciences 2023;19(16):5204-5217
International journal of biological sciences 2023;19(16):5204-5217
Intergenic CircRNA Circ_0007379 Inhibits Colorectal Cancer Progression by Modulating miR-320a Biogenesis in a KSRP-Dependent Manner.
Long F, Li L, Xie C, Ma M, Wu Z, Lu Z, Liu B, Yang M, Zhang F, Ning Z, Zhong C, Yu B, Liu S, Wan L, Tian B, Yang K, Guo Y, Chen M, Chou J, Li X, Hu G, Lin C, Zhang Y
International journal of biological sciences 2023;19(12):3781-3803
International journal of biological sciences 2023;19(12):3781-3803
11β-Hydroxysteroid Dehydrogenase Type 1 Facilitates Osteoporosis by Turning on Osteoclastogenesis through Hippo Signaling.
Li H, Hu S, Wu R, Zhou H, Zhang K, Li K, Lin W, Shi Q, Chen H, Lv S
International journal of biological sciences 2023;19(11):3628-3639
International journal of biological sciences 2023;19(11):3628-3639
Nicotinamide adenine dinucleotide kinase promotes lymph node metastasis of NSCLC via activating ID1 expression through BMP pathway.
Zeng Z, Gao J, Chen T, Zhang Z, Li M, Fan Q, Liu G, Li X, Li Z, Zhong C, Yao F, Sun L, Deng Y, Li M
International journal of biological sciences 2023;19(10):3184-3199
International journal of biological sciences 2023;19(10):3184-3199
Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function.
Ding Z, Gao J, Feng Y, Wang M, Zhao H, Wu R, Zheng X, Feng X, Lai M
Neuropsychiatric disease and treatment 2023;19:2657-2671
Neuropsychiatric disease and treatment 2023;19:2657-2671
M2b macrophages protect against doxorubicin induced cardiotoxicity via alternating autophagy in cardiomyocytes.
Chen S, Huang Y, Huang S, Zhou Z, Liu K, Pan J, Wu Z
PloS one 2023;18(7):e0288422
PloS one 2023;18(7):e0288422
Chaperone-mediated autophagy promotes breast cancer angiogenesis via regulation of aerobic glycolysis.
Chen R, Li P, Fu Y, Wu Z, Xu L, Wang J, Chen S, Yang M, Peng B, Yang Y, Zhang H, Han Q, Li S
PloS one 2023;18(3):e0281577
PloS one 2023;18(3):e0281577
Identification of circRNA-miRNA-mRNA regulatory network and its role in cardiac hypertrophy.
Gong K, Yang K, Xie T, Luo Y, Guo H, Tan Z, Chen J, Wu Q, Gong Y, Wei L, Luo J, Yao Y, Yang Y, Xie L
PloS one 2023;18(3):e0279638
PloS one 2023;18(3):e0279638
Electrophysiological evaluation of an anticancer drug gemcitabine on cardiotoxicity revealing down-regulation and modification of the activation gating properties in the human rapid delayed rectifier potassium channel.
Wei M, Wang P, Zhu X, Morishima M, Liu Y, Zheng M, Liu G, Osanai H, Yoshimura K, Kume S, Kurokawa T, Ono K
PloS one 2023;18(2):e0280656
PloS one 2023;18(2):e0280656
Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor.
Jia B, Hasse A, Shi F, Collins S
PloS one 2023;18(11):e0293636
PloS one 2023;18(11):e0293636
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
Downregulation of RBM17 enhances cisplatin sensitivity and inhibits cell invasion in human hypopharyngeal cancer cells.
Wang X, Chen D, Han G, Wang X, Liu X, Xu B, Liu W, Li H, Zhang M, Ma S, Han Y
Open medicine (Warsaw, Poland) 2023;18(1):20230669
Open medicine (Warsaw, Poland) 2023;18(1):20230669
Combining Porous Se@SiO(2) Nanocomposites and dECM Enhances the Myogenic Differentiation of Adipose-Derived Stem Cells.
Zhang YC, Yang YX, Liu Y, Liu XJ, Dai JH, Gao RS, Hu YY, Fei WY
International journal of nanomedicine 2023;18:7661-7676
International journal of nanomedicine 2023;18:7661-7676
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Zhang H, Zang C, Zhao W, Zhang L, Liu R, Feng Z, Wu J, Cui R
International journal of nanomedicine 2023;18:7047-7063
International journal of nanomedicine 2023;18:7047-7063
Pluronic F-127 Hydrogel Loaded with Human Adipose-Derived Stem Cell-Derived Exosomes Improve Fat Graft Survival via HIF-1α-Mediated Enhancement of Angiogenesis.
Yang F, Li Z, Cai Z, He Y, Ke C, Wang J, Lin M, Li L
International journal of nanomedicine 2023;18:6781-6796
International journal of nanomedicine 2023;18:6781-6796
MicroRNA Let-7 Induces M2 Macrophage Polarization in COPD Emphysema Through the IL-6/STAT3 Pathway.
Liu T, Zhang Z, Shen W, Wu Y, Bian T
International journal of chronic obstructive pulmonary disease 2023;18:575-591
International journal of chronic obstructive pulmonary disease 2023;18:575-591
A Pegylated Liposome Loaded with Raddeanin A for Prostate Cancer Therapy.
He K, Wang T, Chen J, Huang X, Wang Z, Yang Z, Wang K, Zhao W, Jiang J, Zhao L
International journal of nanomedicine 2023;18:4007-4021
International journal of nanomedicine 2023;18:4007-4021
Promoted Abutment-Soft Tissue Integration Around Self-Glazed Zirconia Surfaces with Nanotopography Fabricated by Additive 3D Gel Deposition.
Huang C, Miao X, Li J, Liang J, Xu J, Wu Z
International journal of nanomedicine 2023;18:3141-3155
International journal of nanomedicine 2023;18:3141-3155
Polydopamine Nanoparticles-Based Photothermal Effect Against Adhesion Formation in a Rat Model of Achilles Tendon Laceration Repair.
Zhou Z, Li S, Gong X
International journal of nanomedicine 2023;18:1765-1776
International journal of nanomedicine 2023;18:1765-1776
Combined Verapamil-Polydopamine Nanoformulation Inhibits Adhesion Formation in Achilles Tendon Injury Using Rat Model.
Li S, Gong F, Zhou Z, Gong X
International journal of nanomedicine 2023;18:115-126
International journal of nanomedicine 2023;18:115-126
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Zhu X, Wang S, Cheng Y, Gu H, Zhang X, Teng M, Zhang Y, Wang J, Hua W, Lu X
Frontiers in neuroscience 2023;17:1174455
Frontiers in neuroscience 2023;17:1174455
Icariin reduces cognitive dysfunction induced by surgical trauma in aged rats by inhibiting hippocampal neuroinflammation.
Wang L, Peng G, Chen L, Guo M, Wang B, Zhang Y, Zhou J, Zhong M, Ye J
Frontiers in behavioral neuroscience 2023;17:1162009
Frontiers in behavioral neuroscience 2023;17:1162009
17β-estradiol inhibits TGF-β-induced collagen gel contraction mediated by human Tenon fibroblasts via Smads and MAPK signaling pathways.
Yang CC, Liu MJ, Li YZ, Xu ZH, Liu Y, Guo ZH, Li BH, Yang XX
International journal of ophthalmology 2023;16(9):1441-1449
International journal of ophthalmology 2023;16(9):1441-1449
Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans.
Pan Q, Zhu G, Xu Z, Zhu J, Ouyang J, Tong Y, Zhao N, Zhang X, Cheng Y, Zhang L, Tan Y, Li J, Zhang C, Chen W, Cai SY, Boyer JL, Chai J
Cellular and molecular gastroenterology and hepatology 2023;16(2):223-242
Cellular and molecular gastroenterology and hepatology 2023;16(2):223-242
Neutrophil Extracellular Traps Induce Alveolar Macrophage Pyroptosis by Regulating NLRP3 Deubiquitination, Aggravating the Development of Septic Lung Injury.
Cui Y, Yang Y, Tao W, Peng W, Luo D, Zhao N, Li S, Qian K, Liu F
Journal of inflammation research 2023;16:861-877
Journal of inflammation research 2023;16:861-877
Noncoding RNA-Mediated High Expression of PFKFB3 Correlates with Poor Prognosis and Tumor Immune Infiltration of Lung Adenocarcinoma.
Gu X, Li X, Zhang X, Tong L, Feng R, Liu L, Sun H, Zhang Q, Bian T, Zhang J, Gao L, Zhang C, Liu J, Liu Y
OncoTargets and therapy 2023;16:767-783
OncoTargets and therapy 2023;16:767-783
Mastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis.
Yan Y, Yu L, Chen B, Cao C, Zhao H, Wang Q, Xie D, Xi Y, Zhang C, Cheng J
Journal of inflammation research 2023;16:6179-6193
Journal of inflammation research 2023;16:6179-6193
Unveiling FOS as a Potential Diagnostic Biomarker and Emetine as a Prospective Therapeutic Agent for Diabetic Nephropathy.
Lin J, Li X, Lin Y, Huang Z, He F, Xiong F
Journal of inflammation research 2023;16:6139-6153
Journal of inflammation research 2023;16:6139-6153
Electroacupuncture Alleviates Dry Eye Ocular Pain Through TNF-ɑ Mediated ERK1/2/P2X(3)R Signaling Pathway in SD Rats.
Wan MM, Jin T, Fu ZY, Lai SH, Gao WP
Journal of pain research 2023;16:4241-4252
Journal of pain research 2023;16:4241-4252
PUS1 May Be a Potential Prognostic Biomarker and Therapeutic Target for Hepatocellular Carcinoma.
Lan C, Huang X, Liao X, Zhou X, Peng K, Wei Y, Han C, Peng T, Wang J, Zhu G
Pharmacogenomics and personalized medicine 2023;16:337-355
Pharmacogenomics and personalized medicine 2023;16:337-355
High-Dose Vitamin C Alleviates Pancreatic Necrosis by Inhibiting Platelet Activation Through the CXCL12/CXCR4 Pathway in Severe Acute Pancreatitis.
Gui M, Huang J, Sheng H, Chen Y, Yang Z, Ma L, Wang D, Xu L, Sun W, Liu J, Xu Y, Chen E, Zhao B, Mao E
Journal of inflammation research 2023;16:2865-2877
Journal of inflammation research 2023;16:2865-2877
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
Zhang Y, Liu Y, Zhang X, Yong VW, Xue M
Journal of inflammation research 2023;16:2535-2548
Journal of inflammation research 2023;16:2535-2548
Construction and validation of a risk model based on the key SNARE proteins to predict the prognosis and immune microenvironment of gliomas.
Yin L, Xu Y, Yin J, Cheng H, Xiao W, Wu Y, Ji D, Gao S
Frontiers in molecular neuroscience 2023;16:1304224
Frontiers in molecular neuroscience 2023;16:1304224
Involvement of endoplasmic reticulum stress in trigeminal ganglion corneal neuron injury in dry eye disease.
Zhang J, Lin H, Li F, Wu K, Yang S, Zhou S
Frontiers in molecular neuroscience 2023;16:1083850
Frontiers in molecular neuroscience 2023;16:1083850
Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis.
Zou L, Sun L, Hua R, Wu Y, Sun L, Chen T
Journal of innate immunity 2023;15(1):428-441
Journal of innate immunity 2023;15(1):428-441
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Yuan S, Xu J, Wang M, Huang J, Ma S, Liu Y, Ke Y, Zeng X, Wu K, Wang J, Tian X, Zheng D, Yousaf T, Naz W, Sun J, Chen L, Guo D, Guo M, Sun G
Cellular and molecular gastroenterology and hepatology 2023;15(1):179-195
Cellular and molecular gastroenterology and hepatology 2023;15(1):179-195
Hsa_circ_0007823 Overexpression Suppresses the Progression of Triple-Negative Breast Cancer via Regulating miR-182-5p-FOXO1 Axis.
Yu J, Wang H, Shen W, Zhou Y, Cui J, Li H, Gao B
Breast cancer (Dove Medical Press) 2023;15:695-708
Breast cancer (Dove Medical Press) 2023;15:695-708
Beneficiary Effects of Colchicine on Inflammation and Fibrosis in a Mouse Model of Kidney Injury.
Landau D, Shukri N, Arazi E, Tobar A, Segev Y
Nephron 2023;147(11):693-700
Nephron 2023;147(11):693-700
Orlistat Induces Ferroptosis in Pancreatic Neuroendocrine Tumors by Inactivating the MAPK Pathway.
Ye M, Lu F, Chen J, Yu P, Xu Y, He N, Hu C, Zhong Y, Yan L, Gu D, Xu L, Bai J, Tian Y, Tang Q
Journal of Cancer 2023;14(8):1458-1469
Journal of Cancer 2023;14(8):1458-1469
CHAC2 promotes lung adenocarcinoma by regulating ROS-mediated MAPK pathway activation.
Peng W, Wen L, Jiang R, Deng J, Chen M
Journal of Cancer 2023;14(8):1309-1320
Journal of Cancer 2023;14(8):1309-1320
Endoplasmic Reticulum Stress Promotes Prostate Cancer Cells to Release Exosome and Up-regulate PD-L1 Expression via PI3K/Akt Signaling Pathway in Macrophages.
Xu W, Lu M, Xie S, Zhou D, Zhu M, Liang C
Journal of Cancer 2023;14(6):1062-1074
Journal of Cancer 2023;14(6):1062-1074
Dihydroartemisinin Potentiates VEGFR-TKIs Antitumorigenic Effect on Osteosarcoma by Regulating Loxl2/VEGFA Expression and Lipid Metabolism Pathway.
Ding X, Zhang Y, Liang J, Li Q, Hu H, Zhou Y, Zhang B
Journal of Cancer 2023;14(5):809-820
Journal of Cancer 2023;14(5):809-820
ZFP57 promotes ovarian cancer progression by transcriptionally regulating BRCA1 and managing G1 checkpoint.
Fan W, Xiong R, Zhou Z, Zhang C, Han Y, Shi T, Qiu J, Zhang R
Journal of Cancer 2023;14(11):2039-2050
Journal of Cancer 2023;14(11):2039-2050
An Integrated Analysis Identified TAGLN2 As an Oncogene Indicator Related to Prognosis and Immunity in Pan-Cancer.
Pan T, Wang S, Wang Z
Journal of Cancer 2023;14(10):1809-1836
Journal of Cancer 2023;14(10):1809-1836
miR-21-5p Inhibits the Proliferation, Migration, and Invasion of Glioma by Targeting S100A10.
Gao P, Wang H, Li H, Shu L, Han Z, Li S, Cheng H, Dai X
Journal of Cancer 2023;14(10):1781-1793
Journal of Cancer 2023;14(10):1781-1793
Anti-PAI-1 Monoclonal Antibody Inhibits the Metastasis and Growth of Esophageal Squamous Cell Carcinoma.
Zheng Y, Meng L, Qu L, Zhao C, Wang L, Liu C, Shou C
Journal of Cancer 2023;14(1):114-128
Journal of Cancer 2023;14(1):114-128
Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2.
Su R, Cao W, Ma G, Li W, Li Z, Liu Y, Chen L, Chen Z, Li X, Cui P, Huang G
Frontiers in pharmacology 2023;14:1326245
Frontiers in pharmacology 2023;14:1326245
Integrative analysis of disulfidptosis and immune microenvironment in hepatocellular carcinoma: a putative model and immunotherapeutic strategies.
Yang T, Liu J, Liu F, Lei J, Chen S, Ma Z, Ke P, Yang Q, Wen J, He Y, Duan J, Zeng X
Frontiers in immunology 2023;14:1294677
Frontiers in immunology 2023;14:1294677
Leveraging diverse cell-death related signature predicts the prognosis and immunotherapy response in renal clear cell carcinoma.
Wu Z, Jin M, Xin P, Zhang H
Frontiers in immunology 2023;14:1293729
Frontiers in immunology 2023;14:1293729
Investigating the role of NPR1 in dilated cardiomyopathy and its potential as a therapeutic target for glucocorticoid therapy.
Huang Y, Li T, Gao S, Li S, Zhu X, Li Y, Liu D, Li W, Yang L, Liu K, Zhang Z, Liu C
Frontiers in pharmacology 2023;14:1290253
Frontiers in pharmacology 2023;14:1290253
Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer.
Yang HW, Lan Y, Li A, Wu H, Song ZW, Wan AL, Wang Y, Li SB, Ji S, Wang ZC, Wu XY, Lan T
Frontiers in pharmacology 2023;14:1288883
Frontiers in pharmacology 2023;14:1288883
High expression of P-selectin induces neutrophil extracellular traps via the PSGL-1/Syk/Ca(2+)/PAD4 pathway to exacerbate acute pancreatitis.
Xu Q, Shi M, Ding L, Xia Y, Luo L, Lu X, Zhang X, Deng DYB
Frontiers in immunology 2023;14:1265344
Frontiers in immunology 2023;14:1265344
Evaluation and mechanism study of Pien Tze Huang against EV-A71 infection.
Wang H, Chen F, Wang S, Li Y, Liu T, Li Y, Deng H, Dong J, Pang J, Song D, Zhang D, Yu J, Wang Y
Frontiers in pharmacology 2023;14:1251731
Frontiers in pharmacology 2023;14:1251731
Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma.
Shi B, Ge F, Cai L, Yang Y, Guo X, Wu R, Fan Z, Cao B, Wang N, Si Y, Lin X, Dong W, Sun H
Frontiers in immunology 2023;14:1247288
Frontiers in immunology 2023;14:1247288
Histone ubiquitination-related gene CUL4B promotes lung adenocarcinoma progression and cisplatin resistance.
Yin Y, Zhang L, Zeng Y, Chen D, Guan H, Ran G, Du K
Frontiers in genetics 2023;14:1242137
Frontiers in genetics 2023;14:1242137
Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma.
Nguyen HP, Le AQ, Liu E, Cesarano A, DiMeo F, Perna F, Kapur R, Walker BA, Tran NT
Frontiers in immunology 2023;14:1239614
Frontiers in immunology 2023;14:1239614
Immunological characterization of stroke-heart syndrome and identification of inflammatory therapeutic targets.
Zheng J, Ma Y, Guo X, Wu J
Frontiers in immunology 2023;14:1227104
Frontiers in immunology 2023;14:1227104
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Dun Y, Hu Z, You B, Du Y, Zeng L, Zhao Y, Liu Y, Wu S, Cui N, Yang F, Liu S
Frontiers in endocrinology 2023;14:1223423
Frontiers in endocrinology 2023;14:1223423
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
Liu Q, Gao Y, Cong H, Liao L
Frontiers in pharmacology 2023;14:1214145
Frontiers in pharmacology 2023;14:1214145
YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice.
Jing-Lun Z, Shuang C, Li-Mei Z, Xiao-Dong L
Frontiers in pharmacology 2023;14:1205062
Frontiers in pharmacology 2023;14:1205062
Overexpression of DBT suppresses the aggressiveness of renal clear cell carcinoma and correlates with immune infiltration.
Zhang C, Huang G, Yang J, Jiang Y, Huang R, Ye Z, Huang Y, Hu H, Xi X
Frontiers in immunology 2023;14:1197011
Frontiers in immunology 2023;14:1197011
RNA-sequencing approach for exploring the protective mechanisms of dexmedetomidine on pancreatic injury in severe acute pancreatitis.
Yao J, Lan B, Ma C, Liu Y, Wu X, Feng K, Chen H, Wen Q
Frontiers in pharmacology 2023;14:1189486
Frontiers in pharmacology 2023;14:1189486
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
Yu K, Ding L, An X, Yang Y, Zhang X, Li L, Wang C, Bai F, Yang X
Frontiers in pharmacology 2023;14:1181435
Frontiers in pharmacology 2023;14:1181435
Brown adipose tissue-derived exosomes delay fertility decline in aging mice.
Zhang H, Fang Y, Gao Y, Zeng X, Lu Z, Liu L, Chen C, Huang J, Li Y
Frontiers in endocrinology 2023;14:1180104
Frontiers in endocrinology 2023;14:1180104
Elevated MPP6 expression correlates with an unfavorable prognosis, angiogenesis and immune evasion in hepatocellular carcinoma.
Cheng Q, Wang W, Liu J, Lv Z, Ji W, Yu J, Zhang W, Yang Y
Frontiers in immunology 2023;14:1173848
Frontiers in immunology 2023;14:1173848
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Shu H, Wang Y, Zhang H, Dong Q, Sun L, Tu Y, Liao Q, Feng L, Yao L
Frontiers in pharmacology 2023;14:1169054
Frontiers in pharmacology 2023;14:1169054
N-linoleyltyrosine resisted the growth of non-small cell lung cancer cells via the regulation of CB(1) and CB(2) involvement of PI3K and ERK pathways.
Hu Y, Zhao Z, Liu YT, Xu ZC, Li JY, Yang ZY, Rui-Wang, Yang YQ, Zhang JH, Qiu SY, He T, Wu YY, Liu S
Frontiers in pharmacology 2023;14:1164367
Frontiers in pharmacology 2023;14:1164367
Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity by targeting mitochondrial ROS-mediated ferroptosis.
Ding SB, Chu XL, Jin YX, Jiang JJ, Zhao X, Yu M
Frontiers in pharmacology 2023;14:1148814
Frontiers in pharmacology 2023;14:1148814
Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo.
Li H, Xi Y, Xin X, Feng Q, Hu Y
Frontiers in pharmacology 2023;14:1148737
Frontiers in pharmacology 2023;14:1148737
RNA methylation pattern and immune microenvironment characteristics mediated by m6A regulator in ischemic stroke.
Jia K, Xia W, Su Q, Yang S, Zhang Y, Ni X, Su Z, Meng D
Frontiers in genetics 2023;14:1148510
Frontiers in genetics 2023;14:1148510
Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice.
Huang F, Liu X, Liu J, Xie Y, Zhao L, Liu D, Zeng Z, Liu X, Zheng S, Xiao Z
Frontiers in pharmacology 2023;14:1148410
Frontiers in pharmacology 2023;14:1148410
HZ-A-018, a novel inhibitor of Bruton tyrosine kinase, exerts anti-cancer activity and sensitizes 5-FU in gastric cancer cells.
Liu D, Xu W, Lin B, Ji C, Shen M, Shen S, Ma J, Zhou X, Yan Y, Zhang B, Lin N
Frontiers in pharmacology 2023;14:1142127
Frontiers in pharmacology 2023;14:1142127
Reactivation of mutant p53 in esophageal squamous cell carcinoma by isothiocyanate inhibits tumor growth.
Guan L, Yang Y, Lu Y, Chen Y, Luo X, Xin D, Meng X, Shan Z, Jiang G, Wang F
Frontiers in pharmacology 2023;14:1141420
Frontiers in pharmacology 2023;14:1141420
Establishment and application of a high-throughput screening model for cell adhesion inhibitors.
Sun H, Wang XK, Li JR, Tang M, Li H, Lei L, Li HY, Jiang J, Li JY, Dong B, Jiang JD, Peng ZG
Frontiers in pharmacology 2023;14:1140163
Frontiers in pharmacology 2023;14:1140163
Single-cell transcriptomics reveals immune infiltrate in sepsis.
Tu X, Huang H, Xu S, Li C, Luo S
Frontiers in pharmacology 2023;14:1133145
Frontiers in pharmacology 2023;14:1133145
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
Zhang C, Liao W, Li W, Li M, Xu X, Sun H, Xue Y, Liu L, Qiu J, Zhang C, Zhang X, Ye J, Du J, Deng DYB, Deng W, Li T
Frontiers in physiology 2023;14:1131701
Frontiers in physiology 2023;14:1131701
GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy.
Li X, Liu J, Zeng M, Yang K, Zhang S, Liu Y, Yin X, Zhao C, Wang W, Xiao L
Frontiers in immunology 2023;14:1127612
Frontiers in immunology 2023;14:1127612
GPR35 antagonist CID-2745687 attenuates anchorage-independent cell growth by inhibiting YAP/TAZ activity in colorectal cancer cells.
Otkur W, Liu X, Chen H, Li S, Ling T, Lin H, Yang R, Xia T, Qi H, Piao HL
Frontiers in pharmacology 2023;14:1126119
Frontiers in pharmacology 2023;14:1126119
Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense.
Adzika GK, Mprah R, Rizvi R, Adekunle AO, Ndzie Noah ML, Wowui PI, Adzraku SY, Adu-Amankwaah J, Wang F, Lin Y, Fu L, Liu X, Xiang J, Sun H
Frontiers in immunology 2023;14:1124649
Frontiers in immunology 2023;14:1124649
Administration of protopine prevents mitophagy and acute lung injury in sepsis.
Xiao Z, Long J, Zhang J, Qiu Z, Zhang C, Liu H, Liu X, Wang K, Tang Y, Chen L, Lu Z, Zhao G
Frontiers in pharmacology 2023;14:1104185
Frontiers in pharmacology 2023;14:1104185
APOC1 as a novel diagnostic biomarker for DN based on machine learning algorithms and experiment.
Yu K, Li S, Wang C, Zhang Y, Li L, Fan X, Fang L, Li H, Yang H, Sun J, Yang X
Frontiers in endocrinology 2023;14:1102634
Frontiers in endocrinology 2023;14:1102634
Clinical and functional analyses of the novel STAR c.558C>A in a patient with classic lipoid congenital adrenal hyperplasia.
Liu J, Dai HM, Guang GP, Hu WM, Jin P
Frontiers in genetics 2023;14:1096454
Frontiers in genetics 2023;14:1096454
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway.
Katsouda A, Markou M, Zampas P, Varela A, Davos CH, Vellecco V, Cirino G, Bucci M, Papapetropoulos A
Frontiers in pharmacology 2023;14:1090654
Frontiers in pharmacology 2023;14:1090654
Investigating the role of FADS family members in breast cancer based on bioinformatic analysis and experimental validation.
Zhao T, Gao P, Li Y, Tian H, Ma D, Sun N, Chen C, Zhang Y, Qi X
Frontiers in immunology 2023;14:1074242
Frontiers in immunology 2023;14:1074242
Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels.
Wu W, Yin Y, Feng P, Chen G, Pan L, Gu P, Zhou S, Lin F, Ji S, Zheng C, Deng M
Frontiers in pharmacology 2023;14:1067665
Frontiers in pharmacology 2023;14:1067665
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Kou Y, Rong X, Tang R, Zhang Y, Yang P, Liu H, Ma W, Li M
Frontiers in pharmacology 2023;14:1067085
Frontiers in pharmacology 2023;14:1067085
Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway.
Liu Y, Mo J, Liang F, Jiang S, Xiong J, Meng X, Mo Z
Frontiers in pharmacology 2023;14:1062664
Frontiers in pharmacology 2023;14:1062664
Tachykinin receptor 3 in the lateral habenula alleviates pain and anxiety comorbidity in mice.
Zhang WW, Chen T, Li SY, Wang XY, Liu WB, Wang YQ, Mi WL, Mao-Ying QL, Wang YQ, Chu YX
Frontiers in immunology 2023;14:1049739
Frontiers in immunology 2023;14:1049739
Low-temperature plasma-activated medium enhances the chemosensitivity of colorectal cancer cells by improving hypoxia.
Xu Y, Li Y, Yang X, Lu D, Zheng Y, Tan J, Li W, Chen Q, Liu Y, Gao J, Wang S
American journal of cancer research 2023;13(5):1985-1998
American journal of cancer research 2023;13(5):1985-1998
High expression of peroxisomal D-bifunctional protein in cytosol regulates apoptosis and energy metabolism of hepatocellular carcinoma cells via PI3K/AKT pathway.
Zhang N, Wang YQ, Sun C, Shi Y, Hou LG, Yao M, Hu M, Wang XM, Ma PP, Li WJ, Jiang LL
American journal of cancer research 2023;13(5):1884-1903
American journal of cancer research 2023;13(5):1884-1903
Improving the anti-tumor effect of EGCG in colorectal cancer cells by blocking EGCG-induced YAP activation.
Wang Y, Jin SS, Li DT, Jiang XC, Afrasiyab, Khalid A, Liu X, Wang HL, Wang HY, Wang ZG, Xie ZW, Huang SJ
American journal of cancer research 2023;13(4):1407-1424
American journal of cancer research 2023;13(4):1407-1424
Circ8199 encodes a protein that inhibits the activity of OGT by JAK2-STAT3 pathway in esophageal squamous cell carcinoma.
Li CJ, Li DG, Liu EJ, Jiang GZ
American journal of cancer research 2023;13(3):1107-1117
American journal of cancer research 2023;13(3):1107-1117
GAPDH: unveiling its impact as a key hypoxia-related player in head and neck squamous cell carcinoma tumor progression, prognosis, and therapeutic potential.
Peng C, Ye H, Yi Z
American journal of cancer research 2023;13(12):5846-5867
American journal of cancer research 2023;13(12):5846-5867
iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway.
Guo Y, You Y, Shang FF, Wang X, Huang B, Zhao B, Lv D, Yang S, Xie M, Kong L, Du D, Luo S, Tian X, Xia Y
Theranostics 2023;13(12):4229-4246
Theranostics 2023;13(12):4229-4246
Inhibition of OTUB2 suppresses colorectal cancer cell growth by regulating β-Catenin signaling.
Xu X, Wu G, Han K, Cui X, Feng Y, Mei X, Yang P, You W, Yang Y
American journal of cancer research 2023;13(11):5382-5393
American journal of cancer research 2023;13(11):5382-5393
DOT1L promotes cell proliferation and invasion by epigenetically regulating STAT5B in renal cell carcinoma.
Hou Y, Huang S, Liu J, Wang L, Yuan Y, Liu H, Weng X, Chen Z, Hu J, Liu X
American journal of cancer research 2023;13(1):276-292
American journal of cancer research 2023;13(1):276-292
Combined inhibition of PARP and ATR synergistically potentiates the antitumor activity of HER2-targeting antibody-drug conjugate in HER2-positive cancers.
Li Y, Li L, Fu H, Yao Q, Wang L, Lou L
American journal of cancer research 2023;13(1):161-175
American journal of cancer research 2023;13(1):161-175
LncRNA LBX2-AS1 impacts osteosarcoma sensitivity to JQ-1 by sequestering miR-597-3p away from BRD4.
Li J, Yuan X, Ma C, Li J, Qu G, Yu B, Cai F, Peng Y, Liu L, Zeng D, Jiao Q, Zhang J, Luo X, Liao Q, Lv XB
Frontiers in oncology 2023;13:1139588
Frontiers in oncology 2023;13:1139588
FGFR inhibitors combined with nab-paclitaxel - A promising strategy to treat non-small cell lung cancer and overcome resistance.
Ma F, Zhu X, Niu Y, Nai A, Bashir S, Xiong Y, Dong Y, Li Y, Song J, Xu M
Frontiers in oncology 2023;13:1088444
Frontiers in oncology 2023;13:1088444
Triptolide inhibits the progression of Glioblastoma U251 cells via targeting PROX1.
Yuan C, Liao Y, Liao S, Huang M, Li D, Wu W, Quan Y, Li L, Yu X, Si W
Frontiers in oncology 2023;13:1077640
Frontiers in oncology 2023;13:1077640
A pan-cancer analysis of the role of argininosuccinate synthase 1 in human tumors.
Ding Q, Li R, Wang Q, Yu L, Zi F
Frontiers in oncology 2023;13:1049147
Frontiers in oncology 2023;13:1049147
BASP1 is a prognostic biomarker associated with immunotherapeutic response in head and neck squamous cell carcinoma.
Pan X, Xu X, Wang L, Zhang S, Chen Y, Yang R, Chen X, Cheng B, Xia J, Ren X
Frontiers in oncology 2023;13:1021262
Frontiers in oncology 2023;13:1021262
S100 calcium-binding protein A9 promotes skin regeneration through toll-like receptor 4 during tissue expansion.
Zhang Y, Song Y, Du J, Liu W, Dong C, Huang Z, Zhang Z, Yang L, Wang T, Xiong S, Dong L, Guo Y, Dang J, He Q, Yu Z, Ma X
Burns & trauma 2023;11:tkad030
Burns & trauma 2023;11:tkad030
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
Lv D, Xu Z, Cheng P, Hu Z, Dong Y, Rong Y, Xu H, Wang Z, Cao X, Deng W, Tang B
Burns & trauma 2023;11:tkad024
Burns & trauma 2023;11:tkad024
Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation.
Liu Y, Gao Q, Feng X, Chen G, Jiang X, Chen D, Yang Z
Gastroenterology report 2023;11:goad033
Gastroenterology report 2023;11:goad033
Fascin actin-bundling protein 1 regulates non-small cell lung cancer progression by influencing the transcription and splicing of tumorigenesis-related genes.
Sun Q, Liu R, Zhang H, Zong L, Jing X, Ma L, Li J, Zhang L
PeerJ 2023;11:e16526
PeerJ 2023;11:e16526
Sirtuin 1 alleviates alcoholic liver disease by inhibiting HMGB1 acetylation and translocation.
Fu J, Deng W, Ge J, Fu S, Li P, Wu H, Wang J, Gao Y, Gao H, Wu T
PeerJ 2023;11:e16480
PeerJ 2023;11:e16480
Identification and validation of hub genes involved in foam cell formation and atherosclerosis development via bioinformatics.
Teng D, Chen H, Jia W, Ren Q, Ding X, Zhang L, Gong L, Wang H, Zhong L, Yang J
PeerJ 2023;11:e16122
PeerJ 2023;11:e16122
Daidzein alleviates osteoporosis by promoting osteogenesis and angiogenesis coupling.
Jia J, He R, Yao Z, Su J, Deng S, Chen K, Yu B
PeerJ 2023;11:e16121
PeerJ 2023;11:e16121
TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea.
Huang Y, Liu D, Chen M, Xu S, Peng Q, Zhu Y, Long J, Liu T, Deng Z, Xie H, Li J, Liu F, Xiao W
PeerJ 2023;11:e15976
PeerJ 2023;11:e15976
Identification of iron metabolism-related genes as prognostic indicators for papillary thyroid carcinoma: a retrospective study.
Jin T, Ge L, Chen J, Wang W, Zhang L, Ge M
PeerJ 2023;11:e15592
PeerJ 2023;11:e15592
Discovery of grey matter lesion-related immune genes for diagnostic prediction in multiple sclerosis.
Zhao P, Liu X, Wang Y, Zhang X, Wang H, Du X, Du Z, Yang L, Hou J
PeerJ 2023;11:e15299
PeerJ 2023;11:e15299
Pathological mechanism of heart failure with preserved ejection fraction in rats based on iTRAQ technology.
Xu H, Gao K, Liu C, Li T, Ding Y, Ma J
PeerJ 2023;11:e15280
PeerJ 2023;11:e15280
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
Yi C, Wu S, Duan Q, Liu L, Li L, Luo Y, Wang A
PeerJ 2023;11:e15060
PeerJ 2023;11:e15060
Roles of cuproptosis-related gene DLAT in various cancers: a bioinformatic analysis and preliminary verification on pro-survival autophagy.
Yang Q, Zeng S, Liu W
PeerJ 2023;11:e15019
PeerJ 2023;11:e15019
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Tan X, Yang X, Xu X, Peng Y, Li X, Deng Y, Zhang X, Qiu W, Wu D, Ruan Y, Zhi C
Frontiers in chemistry 2023;11:1280999
Frontiers in chemistry 2023;11:1280999
Regulation of cleavage embryo genes upon DRP1 inhibition in mouse embryonic stem cells.
Guo SM, Zhang YR, Ma BX, Zhou LQ, Yin Y
Frontiers in cell and developmental biology 2023;11:1191797
Frontiers in cell and developmental biology 2023;11:1191797
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
Chen S, Wang Y, Kong L, Ji Y, Cui J, Shen W
Frontiers in cell and developmental biology 2023;11:1178045
Frontiers in cell and developmental biology 2023;11:1178045
An miRNA-mRNA integrative analysis in human placentas and mice: role of the Smad2/miR-155-5p axis in the development of fetal growth restriction.
Wu JX, Shi M, Gong BM, Ji BW, Hu CC, Wang GC, Lei L, Tang C, Sun LV, Wu XH, Wang X
Frontiers in bioengineering and biotechnology 2023;11:1159805
Frontiers in bioengineering and biotechnology 2023;11:1159805
A construct of adipose-derived mesenchymal stem cells-laden collagen scaffold for fertility restoration by inhibiting fibrosis in a rat model of endometrial injury.
Dai Y, Xin L, Hu S, Xu S, Huang D, Jin X, Chen J, Chan RWS, Ng EHY, Yeung WSB, Ma L, Zhang S
Regenerative biomaterials 2023;10:rbad080
Regenerative biomaterials 2023;10:rbad080
Micropatterned composite membrane guides oriented cell growth and vascularization for accelerating wound healing.
Li J, Liu X, Tao W, Li Y, Du Y, Zhang S
Regenerative biomaterials 2023;10:rbac108
Regenerative biomaterials 2023;10:rbac108
Feline umbilical cord-derived mesenchymal stem cells: isolation, identification, and antioxidative stress role through NF-κB signaling pathway.
Zhai ZH, Li J, You Z, Cai Y, Yang J, An J, Zhao DP, Wang HJ, Dou MM, Du R, Qin J
Frontiers in veterinary science 2023;10:1203012
Frontiers in veterinary science 2023;10:1203012
Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach.
Reivan Ortiz GG, Ciongradi CI, Chaitanya MVNL, Narayanan J, Mohany M, Al-Rejaie SS, Arias-Gonzáles JL, Sârbu I, Assefi M, Akram SV, Döğüş Y, Bahrami A, Akhavan-Sigari R
Frontiers in molecular biosciences 2023;10:1189527
Frontiers in molecular biosciences 2023;10:1189527
Ischemia/reperfusion-activated ferroptosis in the early stage triggers excessive inflammation to aggregate lung injury in rats.
Liu X, Pan B, Wang X, Xu J, Wang X, Song Z, Zhang E, Wang F, Wang W
Frontiers in medicine 2023;10:1181286
Frontiers in medicine 2023;10:1181286
Berbamine, a bioactive alkaloid, suppresses equine herpesvirus type 1 in vitro and in vivo.
Li Z, He Y, Ge L, Quan R, Chen J, Hu Y, Sa R, Liu J, Ran D, Fu Q, Shi H
Frontiers in veterinary science 2023;10:1163780
Frontiers in veterinary science 2023;10:1163780
SADS-CoV nsp1 inhibits the IFN-β production by preventing TBK1 phosphorylation and inducing CBP degradation.
Xiang Y, Mou C, Shi K, Chen X, Meng X, Bao W, Chen Z
Journal of medical virology 2023 Sep;95(9):e29104
Journal of medical virology 2023 Sep;95(9):e29104
Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study.
Sun H, Peng G, Chen K, Xiong Z, Zhuang Y, Liu M, Ning X, Yang H, Deng J
Heliyon 2023 Sep;9(9):e19975
Heliyon 2023 Sep;9(9):e19975
Hsa_circRNA_0084043 promoting tumorigenesis in glioma through miR-577 sponging.
Qian J, Chen C, Zhao C, Xu X, Xu Y, Zhang Y, Qian C
Heliyon 2023 Sep;9(9):e19219
Heliyon 2023 Sep;9(9):e19219
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization.
Qu K, Wang C, Huang L, Qin X, Zhang K, Qiu J, Wang G
APL bioengineering 2023 Sep;7(3):036104
APL bioengineering 2023 Sep;7(3):036104
EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2.
Wang B, Jin Y, Liu J, Liu Q, Shen Y, Zuo S, Yu Y
Redox biology 2023 Sep;65:102825
Redox biology 2023 Sep;65:102825
Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization.
Jiang K, Lu S, Li D, Liu M, Jin H, Lei B, Wang S, Long K, He S, Zhong F
Journal of gastroenterology 2023 Sep;58(9):894-907
Journal of gastroenterology 2023 Sep;58(9):894-907
CKBA suppresses mast cell activation via ERK signaling pathway in murine atopic dermatitis.
Tong J, Li Y, Cai X, Lou F, Sun Y, Wang Z, Zheng X, Zhou H, Zhang Z, Fang Z, Ding W, Deng S, Xu Z, Niu X, Wang H
European journal of immunology 2023 Sep;53(9):e2350374
European journal of immunology 2023 Sep;53(9):e2350374
Exosomal miR-21-5p derived from multiple myeloma cells promote renal epithelial-mesenchymal transition through targeting TGF-β/SMAD7 signalling pathway.
Liu L, Liu L, Liu R, Liu J, Cheng Q
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):711-718
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):711-718
SPAG5, the upstream protein of Wnt and the target of curcumin, inhibits hepatocellular carcinoma.
Li H, Qin Y, Huang Y, Wang J, Ren B
Oncology reports 2023 Sep;50(3)
Oncology reports 2023 Sep;50(3)
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
Wu Z, Tang W, Ibrahim FEEM, Chen X, Yan H, Tao C, Wang Z, Guo Y, Fu Y, Wang Q, Ge Y
Neurochemical research 2023 Sep;48(9):2881-2894
Neurochemical research 2023 Sep;48(9):2881-2894
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
Wei X, Huang C, Chen K, Liu S, Wang M, Yang L, Wang Y
Neurochemical research 2023 Sep;48(9):2687-2700
Neurochemical research 2023 Sep;48(9):2687-2700
Effects of photodynamic therapy using Red LED-light combined with hypocrellin B on apoptotic signaling in cutaneous squamous cell carcinoma A431 cells.
Liu Y, Cao Z, Wei G
Photodiagnosis and photodynamic therapy 2023 Sep;43:103683
Photodiagnosis and photodynamic therapy 2023 Sep;43:103683
Hyperoside prevents doxorubicin-induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway.
Wei S, Ma W, Jiang C, Liu J, Liu J, Zhang B, Li W
Phytotherapy research : PTR 2023 Sep;37(9):4196-4209
Phytotherapy research : PTR 2023 Sep;37(9):4196-4209
Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain.
Clark NE, Katolik A, Gallant P, Welch A, Murphy E, Buerer L, Schorl C, Naik N, Naik MT, Holloway SP, Cano K, Weintraub ST, Howard KM, Hart PJ, Jogl G, Damha MJ, Fairbrother WG
The Journal of biological chemistry 2023 Sep;299(9):105100
The Journal of biological chemistry 2023 Sep;299(9):105100
Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment.
Cheng S, Liu L, Wang D, Li Y, Li S, Yuan J, Huang S, Xu Z, Jia B, Li Z, Dong J
CNS neuroscience & therapeutics 2023 Sep;29(9):2690-2704
CNS neuroscience & therapeutics 2023 Sep;29(9):2690-2704
ORFV entry into host cells via clathrin-mediated endocytosis and macropinocytosis.
Tang X, Xie Y, Li G, Niyazbekova Z, Li S, Chang J, Chen D, Ma W
Veterinary microbiology 2023 Sep;284:109831
Veterinary microbiology 2023 Sep;284:109831
Resveratrol‑mediated activation of SIRT1 inhibits the PERK‑eIF2α‑ATF4 pathway and mitigates bupivacaine‑induced neurotoxicity in PC12 cells.
Luo Y, Hu N, Zhao Y, Lai J, Luo X, Liu J
Experimental and therapeutic medicine 2023 Sep;26(3):433
Experimental and therapeutic medicine 2023 Sep;26(3):433
SLC17A9 expression levels in a pan‑cancer panel and validation of the role of SLC17A9 as a novel prognostic biomarker for osteosarcoma.
Li J, Wu F, Su L, Zhu H, Yao J, Zhang M
Oncology letters 2023 Sep;26(3):383
Oncology letters 2023 Sep;26(3):383
High expression of NF-κB inducing kinase in the bulge region of hair follicle induces tumor.
Duan W, Guo S, Huang HP, Tian Y, Li Z, Bi Y, Yi L, Cao M, Guo M, Li Y, Liu Y, Li C
Immunobiology 2023 Sep;228(5):152705
Immunobiology 2023 Sep;228(5):152705
EIF4A3-regulated hsa_circ_0001445 can inhibit the progression of laryngeal squamous cell carcinoma via hsa-miR-432-5p-dependent up-regulation of RGMA expression.
Yu M, Cao H, Yang J, Liu T, Gao J, Wang B
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):2038-2056
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):2038-2056
A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance.
Hao J, Huang J, Hua C, Zuo Y, Yu W, Wu X, Li L, Xue G, Wan X, Ru L, Guo Z, Han S, Deng W, Lin F, Guo W
PLoS biology 2023 Sep;21(9):e3002256
PLoS biology 2023 Sep;21(9):e3002256
Retinal cell-targeted liposomal ginsenoside Rg3 attenuates retinal ischemia-reperfusion injury via alleviating oxidative stress and promoting microglia/macrophage M2 polarization.
Huang Y, Lu J, Zhao L, Fu X, Peng S, Zhang W, Wang R, Yuan W, Luo R, Wang X, Li Z, Zhang Z
Free radical biology & medicine 2023 Sep;206:162-179
Free radical biology & medicine 2023 Sep;206:162-179
Dexmedetomidine alleviates anxiety-like behaviors in female mice with musculoskeletal pain through SIRT1/p53 axis.
Zhou Q, Jiang N, Dong Y, Tian K
Brain research bulletin 2023 Sep;201:110698
Brain research bulletin 2023 Sep;201:110698
HPV E7-drived ALKBH5 promotes cervical cancer progression by modulating m6A modification of PAK5.
Huo FC, Zhu ZM, Du WQ, Pan YJ, Jiang X, Kang MJ, Liu BW, Mou J, Pei DS
Pharmacological research 2023 Sep;195:106863
Pharmacological research 2023 Sep;195:106863
Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing.
Yan Y, Wu L, Yuan Y, Wang H, Yin H, Li M, Chai L, Liang R, Liu Y, Zhao D, Xing J, Li P, Li X
PLoS pathogens 2023 Sep;19(9):e1011641
PLoS pathogens 2023 Sep;19(9):e1011641
Engineered Cytokine-Primed Extracellular Vesicles with High PD-L1 Expression Ameliorate Type 1 Diabetes.
Wang L, Qi C, Cao H, Zhang Y, Liu X, Qiu L, Wang H, Xu L, Wu Z, Liu J, Wang S, Kong D, Wang Y
Small (Weinheim an der Bergstrasse, Germany) 2023 Sep;19(38):e2301019
Small (Weinheim an der Bergstrasse, Germany) 2023 Sep;19(38):e2301019
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug.
Huang Y, Lin Y, Li B, Zhang F, Zhan C, Xie X, Yao Z, Wu C, Ping Y, Shen J
Asian journal of pharmaceutical sciences 2023 Sep;18(5):100844
Asian journal of pharmaceutical sciences 2023 Sep;18(5):100844
Fgfr1 deficiency in osteocytes leads to increased bone mass by enhancing Wnt/β-catenin signaling.
Tang Y, Yang P, Jin M, Huang S, Chen H, Chen L, Yang J, Su N
Bone 2023 Sep;174:116817
Bone 2023 Sep;174:116817
BLM promotes malignancy in PCa by inducing KRAS expression and RhoA suppression via its interaction with HDGF and activation of MAPK/ERK pathway.
Guo Y, Xu H, Huang M, Ruan Y
Journal of cell communication and signaling 2023 Sep;17(3):757-772
Journal of cell communication and signaling 2023 Sep;17(3):757-772
High glucose-induced IL-7/IL-7R upregulation of dermal fibroblasts inhibits angiogenesis in a paracrine way in delayed diabetic wound healing.
Gao R, Zhou P, Li Y, Li Q
Journal of cell communication and signaling 2023 Sep;17(3):1023-1038
Journal of cell communication and signaling 2023 Sep;17(3):1023-1038
Total sesquiterpenoids from Eupatorium lindleyanum DC. attenuate bleomycin-induced lung fibrosis by suppressing myofibroblast transition.
Sun X, Zhu M, Xia W, Xu X, Zhang J, Jiang X
Fitoterapia 2023 Sep;169:105567
Fitoterapia 2023 Sep;169:105567
The Chinese medicine Xin-tong-tai granule protects atherosclerosis by regulating oxidative stress through NOX/ROS/NF-κB signal pathway.
Wei JM, Yuan H, Liu CX, Wang ZY, Shi M, Guo ZH, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115200
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115200
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Degradation of histone deacetylase 6 alleviates ROS-mediated apoptosis in renal ischemia-reperfusion injury.
Xia K, Qiu T, Jian Y, Liu H, Chen H, Liu X, Chen Z, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115128
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115128
PM(2.5) induces the inflammatory response in rat spleen lymphocytes through autophagy activation of NLRP3 inflammasome.
Guan L, Shi H, Tian J, Wang X, Liu N, Wang C, Zhang Z
Molecular immunology 2023 Sep;161:74-81
Molecular immunology 2023 Sep;161:74-81
Restraint stress promotes monobenzone-induced depigmentation in mice via the activation of glucocorticoid receptor/macrophage migration inhibitory factor signaling pathway.
Tang N, Liu XT, Wen WL, Liang TS, Lv XT, Li QL, Wang GE, Wu YH
Molecular immunology 2023 Sep;161:33-43
Molecular immunology 2023 Sep;161:33-43
IL-21 induces pyroptosis of Treg cells via Akt-mTOR-NLRP3-caspase 1 axis in eosinophilic chronic rhinosinusitis.
Chang L, Wu H, Huang W, Li Y, Chen Y, Li X, Yao Z, Chen X, Lai X, Zheng R, Huang Z, Wu X, Zhang G
The Journal of allergy and clinical immunology 2023 Sep;152(3):641-655.e14
The Journal of allergy and clinical immunology 2023 Sep;152(3):641-655.e14
Discovery of potent and effective inhibitors containing sulfoxide structures targeting EML4-ALK rearrangement and EGFR mutant non-small cell lung cancer.
An B, Fan Y, Li W, Nie W, Nie H, Wang M, Feng J, Yao H, Zhang Y, Li X, Tian G
Bioorganic chemistry 2023 Sep;138:106653
Bioorganic chemistry 2023 Sep;138:106653
Inhibition of Microglial Activation by Delayed Mild Hypothermia Reduced Preoligodendrocyte Injury in a Neonatal Rat Brain Slice Model.
Liang S, Ti Y, Huang J, Li X, Zhou W
Therapeutic hypothermia and temperature management 2023 Sep;13(3):134-140
Therapeutic hypothermia and temperature management 2023 Sep;13(3):134-140
MiR-222-3p suppresses C2C12 myoblast proliferation and differentiation via the inhibition of IRS-1/PI3K/Akt pathway.
Wei X, Wang J, Sun Y, Zhao T, Luo X, Lu J, Hou W, Yu X, Xue L, Yan Y, Wang H
Journal of cellular biochemistry 2023 Sep;124(9):1379-1390
Journal of cellular biochemistry 2023 Sep;124(9):1379-1390
GPER governs the immune infiltration of gastric cancer and activates the NF-κB/ROS/Apoptosis pathway in gastric mucosal epithelium.
Yang X, Zhang J, Ma J, Huang J, Wang Y, Wang P, Wang F, Tang X
International immunopharmacology 2023 Sep;122:110641
International immunopharmacology 2023 Sep;122:110641
Artesunate alleviates intestinal ischemia/reperfusion induced acute lung injury via up-regulating AKT and HO-1 signal pathway in mice.
Ji T, Chen M, Liu Y, Jiang H, Li N, He X
International immunopharmacology 2023 Sep;122:110571
International immunopharmacology 2023 Sep;122:110571
3,4-benzo[a]pyrene aggravates myocardial infarction injury by activating NLRP3-related pyroptosis through PINK1/Parkin-mitophagy-mPTP opening axis.
Wu BS, Xiang HQ, Yu YW, Liu S, Song DY, Wu C, Lin ZH, Zhu CX, Xue YJ, Ji KT
International immunopharmacology 2023 Sep;122:110481
International immunopharmacology 2023 Sep;122:110481
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
Wei Y, Liu X, Jiang Y, Guan Q, Tian Y, Li J, Zhao P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis.
Qin T, Hasnat M, Wang Z, Hassan HM, Zhou Y, Yuan Z, Zhang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154971
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154971
Pure total flavonoids from citrus alleviate oxidative stress and inflammation in nonalcoholic fatty liver disease by regulating the miR-137-3p/NOXA2/NOX2 pathway.
Yan JB, Nie YM, Xu SM, Zhang S, Chen ZY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154944
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154944
FTZ polysaccharides ameliorate kidney injury in diabetic mice by regulating gut-kidney axis.
Lan T, Tang T, Li Y, Duan Y, Yuan Q, Liu W, Ren Y, Li N, Liu X, Zhang Y, Li X, Jin G, Wang S, Guo J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154935
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154935
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor.
Yang L, Liu T, Zhuo Y, Li D, Li D, Liu J, Gao H, Zhang L, Lin J, Wang X
Cellular signalling 2023 Sep;109:110768
Cellular signalling 2023 Sep;109:110768
Oncogenic Role of the NFATC2/NEDD4/FBP1 Axis in Cholangiocarcinoma.
Zhao W, Zhao J, Li K, Hu Y, Yang D, Tan B, Shi J
Laboratory investigation; a journal of technical methods and pathology 2023 Sep;103(9):100193
Laboratory investigation; a journal of technical methods and pathology 2023 Sep;103(9):100193
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Zhao X, Guo B, Sun W, Yu J, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
The NLRP11 Protein Bridges the Histone Lysine Acetyltransferase KAT7 to Acetylate Vimentin in the Early Stage of Lung Adenocarcinoma.
Yang R, Peng W, Shi S, Peng X, Cai Q, Zhao Z, He B, Tu G, Yin W, Chen Y, Zhang Y, Liu F, Wang X, Xiao D, Tao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2300971
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2300971
A strategy for Cas13 miniaturization based on the structure and AlphaFold.
Zhao F, Zhang T, Sun X, Zhang X, Chen L, Wang H, Li J, Fan P, Lai L, Sui T, Li Z
Nature communications 2023 Sep 8;14(1):5545
Nature communications 2023 Sep 8;14(1):5545
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Liu J, Chen Y, Chen H, Wang Y, Li D, Zhang Q, Chai L, Qiu Y, Zhang J, Shen N, Wang Q, Wang J, Li M
Respiratory research 2023 Sep 6;24(1):216
Respiratory research 2023 Sep 6;24(1):216
CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.
Chen J, Lin Y, Zheng S, Chen Q, Tang S, Zhong X
Journal of translational medicine 2023 Sep 6;21(1):600
Journal of translational medicine 2023 Sep 6;21(1):600
RGS5 augments astrocyte activation and facilitates neuroinflammation via TNF signaling.
Yin S, Ma XY, Sun YF, Yin YQ, Long Y, Zhao CL, Ma JW, Li S, Hu Y, Li MT, Hu G, Zhou JW
Journal of neuroinflammation 2023 Sep 6;20(1):203
Journal of neuroinflammation 2023 Sep 6;20(1):203
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
Xia B, Li Q, Zheng K, Wu J, Huang C, Liu K, You Q, Yuan X
European journal of pharmacology 2023 Sep 5;954:175864
European journal of pharmacology 2023 Sep 5;954:175864
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Ning J, Pei Z, Wang M, Hu H, Chen M, Liu Q, Wu M, Yang P, Geng Z, Zheng J, Du Z, Hu W, Wang Q, Pang Y, Bao L, Niu Y, Leng S, Zhang R
Journal of hazardous materials 2023 Sep 5;457:131791
Journal of hazardous materials 2023 Sep 5;457:131791
Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171.
Xiang R, Lu M, Wu T, Yang C, Jia Y, Liu X, Deng M, Ge Y, Xu J, Cai T, Ling Y, Zhou Y
European journal of medicinal chemistry 2023 Sep 5;257:115514
European journal of medicinal chemistry 2023 Sep 5;257:115514
Vascular wall microenvironment: exosomes secreted by adventitial fibroblasts induced vascular calcification.
Zheng MH, Shan SK, Lin X, Xu F, Wu F, Guo B, Li FX, Zhou ZA, Wang Y, Lei LM, Tang KX, Duan JY, Wu YY, Cao YC, Liao XB, Yuan LQ
Journal of nanobiotechnology 2023 Sep 4;21(1):315
Journal of nanobiotechnology 2023 Sep 4;21(1):315
HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunction.
Zhu C, Piao Z, Jin L
Orphanet journal of rare diseases 2023 Sep 4;18(1):266
Orphanet journal of rare diseases 2023 Sep 4;18(1):266
Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2.
Liu Q, Bi Y, Song S, Zhu K, Qiao X, Wang H, Ji G
Stem cell research & therapy 2023 Sep 4;14(1):234
Stem cell research & therapy 2023 Sep 4;14(1):234
Activation of AMPK ameliorates acute severe pancreatitis by suppressing pancreatic acinar cell necroptosis in obese mice models.
Wang K, Zhao A, Tayier D, Tan K, Song W, Cheng Q, Li X, Chen Z, Wei Q, Yuan Y, Yang Z
Cell death discovery 2023 Sep 30;9(1):363
Cell death discovery 2023 Sep 30;9(1):363
Effects of infliximab on oxidative stress and inflammation of H9c2 cells induced by H2O2.
Yang T, Hu SL, Li L, Wang Y, Jiang T
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Sep 30;69(9):213-218
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Sep 30;69(9):213-218
LINC00460 promotes angiogenesis by enhancing NF-κB-mediated VEGFA expression in cervical cancer cells.
Li F, Zhu W
Biochemical and biophysical research communications 2023 Sep 3;671:146-152
Biochemical and biophysical research communications 2023 Sep 3;671:146-152
Cla4 phosphorylates histone methyltransferase Set1 to prevent its degradation by the APC/C(Cdh1) complex.
Gong X, Wang S, Yu Q, Wang M, Ge F, Li S, Yu X
Science advances 2023 Sep 29;9(39):eadi7238
Science advances 2023 Sep 29;9(39):eadi7238
Derivation of Arbas Cashmere Goat Induced Pluripotent Stem Cells in LCDM with Trophectoderm Lineage Differentiation and Interspecies Chimeric Abilities.
Liu F, Wang J, Yue Y, Li C, Zhang X, Xiang J, Wang H, Li X
International journal of molecular sciences 2023 Sep 29;24(19)
International journal of molecular sciences 2023 Sep 29;24(19)
PLCD3 promotes malignant cell behaviors in esophageal squamous cell carcinoma via the PI3K/AKT/P21 signaling.
Wang M, Gao M, Chen Y, Wu J, Wang X, Shu Y
BMC cancer 2023 Sep 29;23(1):921
BMC cancer 2023 Sep 29;23(1):921
Identification of common genetic features and pathways involved in pulmonary lymphangioleiomyomatosis and ER-positive breast cancer.
Yang L, Xiao Y, Ren S
Medicine 2023 Sep 29;102(39):e34810
Medicine 2023 Sep 29;102(39):e34810
The Effects of Chronic Unpredictable Mild Stress and Semi-Pure Diets on the Brain, Gut and Adrenal Medulla in C57BL6 Mice.
Herselman MF, Bobrovskaya L
International journal of molecular sciences 2023 Sep 27;24(19)
International journal of molecular sciences 2023 Sep 27;24(19)
Human osteoarthritic articular cartilage stem cells suppress osteoclasts and improve subchondral bone remodeling in experimental knee osteoarthritis partially by releasing TNFAIP3.
Li ZL, Li XT, Hao RC, Wang FY, Wang YX, Zhao ZD, Li PL, Yin BF, Mao N, Ding L, Zhu H
Stem cell research & therapy 2023 Sep 27;14(1):253
Stem cell research & therapy 2023 Sep 27;14(1):253
PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C.
Xu N, Ren Y, Bao Y, Shen X, Kang J, Wang N, Wang Z, Han X, Li Z, Zuo J, Wei GH, Wang Z, Zong WX, Liu W, Xie G, Wang Y
Cell reports 2023 Sep 26;42(9):113041
Cell reports 2023 Sep 26;42(9):113041
Krüppel-like Factor 15 Suppresses Ferroptosis by Activating an NRF2/GPX4 Signal to Protect against Folic Acid-Induced Acute Kidney Injury.
Yang X, Dong S, Fan Y, Xia Y, Yang F, Chen Z, Chen D, Zhang M, Liang D, Zeng C
International journal of molecular sciences 2023 Sep 26;24(19)
International journal of molecular sciences 2023 Sep 26;24(19)
Long intergenic non-coding RNA DIO3OS promotes osteosarcoma metastasis via activation of the TGF-β signaling pathway: a potential diagnostic and immunotherapeutic target for osteosarcoma.
Yuan J, Jia J, Wu T, Du Z, Chen Q, Zhang J, Wu Z, Yuan Z, Zhao X, Liu J, Guo J, Cheng X
Cancer cell international 2023 Sep 26;23(1):215
Cancer cell international 2023 Sep 26;23(1):215
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
Luo FF, Wang J, Zhang ZF, Lin ST, Huang TJ, Liu BQ, Fan ML, Peng LX, Zheng ST, Yang CF, Huang BJ
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement.
Zhang C, Wang H, Liu Q, Dai S, Tian G, Wei X, Li X, Zhao L, Shan B
Journal of experimental & clinical cancer research : CR 2023 Sep 23;42(1):246
Journal of experimental & clinical cancer research : CR 2023 Sep 23;42(1):246
Synovium is a sensitive tissue for mapping the negative effects of systemic iron overload in osteoarthritis: identification and validation of two potential targets.
Jin Z, Zhang H, Bai L, Yue L, Zhang W, Liang J, Chang B, Yang Y, Hu Z, Chen L, Guo C
Journal of translational medicine 2023 Sep 23;21(1):661
Journal of translational medicine 2023 Sep 23;21(1):661
METTL3 exerts synergistic effects on m6A methylation and histone modification to regulate the function of VGF in lung adenocarcinoma.
Shi K, Sa R, Dou L, Wu Y, Dong Z, Fu X, Yu H
Clinical epigenetics 2023 Sep 23;15(1):153
Clinical epigenetics 2023 Sep 23;15(1):153
δ-Tocotrienol preconditioning improves the capability of bone marrow-derived mesenchymal stem cells in promoting wound healing by inhibiting BACH1-related ferroptosis.
He X, Wang D, Yi Y, Tan Y, Wu M, Wang H, Hu W, Chen H, Zhang Q, Wu Y
Cell death discovery 2023 Sep 22;9(1):349
Cell death discovery 2023 Sep 22;9(1):349
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
Sheng B, Wang W, Xia D, Qu X
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
The oncogenic miR-429 promotes triple-negative breast cancer progression by degrading DLC1.
Li Y, Meng X, Luo Y, Luo S, Li J, Zeng J, Huang X, Wang J
Aging 2023 Sep 21;15(18):9809-9821
Aging 2023 Sep 21;15(18):9809-9821
A novel risk model of three gefitinib-related genes FBP1, SBK1 and AURKA is related to the immune microenvironment and is predicting prognosis of lung adenocarcinoma patients.
Guo Q, Li K, Jiang N, Zhou R, Rao XR, Wu CY
Aging 2023 Sep 21;15(18):9633-9660
Aging 2023 Sep 21;15(18):9633-9660
M(6)A-mediated upregulation of HOXC10 promotes human hepatocellular carcinoma development through PTEN/AKT/mTOR signaling pathway.
Li M, Guo Q, Shi Q, Rao Y, Dong Y, Chen F, Qi X
Discover oncology 2023 Sep 21;14(1):175
Discover oncology 2023 Sep 21;14(1):175
Near-Infrared Light-Controlled MicroRNA-21-Loaded Upconversion Nanoparticles to Promote Bone Formation in the Midpalatal Suture.
Liu B, Wang B, Wang Z, Meng Y, Li Y, Li L, Wang J, Zhai M, Liu R, Wei F
ACS applied materials & interfaces 2023 Sep 20;15(37):43503-43514
ACS applied materials & interfaces 2023 Sep 20;15(37):43503-43514
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Dong Y, Tan H, Wang L, Liu Z
Cancer cell international 2023 Sep 2;23(1):191
Cancer cell international 2023 Sep 2;23(1):191
Hypoxia-inducible factor upregulation by roxadustat attenuates drug reward by altering brain iron homoeostasis.
Yan P, Li N, Ma M, Liu Z, Yang H, Li J, Wan C, Gao S, Li S, Zheng L, Waddington JL, Xu L, Zhen X
Signal transduction and targeted therapy 2023 Sep 18;8(1):355
Signal transduction and targeted therapy 2023 Sep 18;8(1):355
Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression.
Li XW, Yuan SC, Wang M, Su ZH, Zhao M, Li T, Zhang XM, Xue W, Li WH
Biochemical and biophysical research communications 2023 Sep 17;673:73-80
Biochemical and biophysical research communications 2023 Sep 17;673:73-80
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.
Malnar Črnigoj M, Čerček U, Yin X, Ho MT, Repic Lampret B, Neumann M, Hermann A, Rouleau G, Suter B, Mayr M, Rogelj B
Nature communications 2023 Sep 16;14(1):5764
Nature communications 2023 Sep 16;14(1):5764
Kinetin inhibits hepatic stellate cell activation and induces apoptosis via interactions with the TGF-β1/Smad signaling pathway.
Jin FC, Chen JJ, Xu QX, Zhou MH, Lin Y, Zhang QW, Zhang CC, Zhang ZG
Toxicology and applied pharmacology 2023 Sep 15;475:116655
Toxicology and applied pharmacology 2023 Sep 15;475:116655
FDX1 regulates leydig cell ferroptosis mediates PM(2.5)-induced testicular dysfunction of mice.
Li L, Pei Z, Wu R, Zhang Y, Pang Y, Hu H, Hu W, Geng Z, Feng T, Niu Y, Hao G, Zhang R
Ecotoxicology and environmental safety 2023 Sep 15;263:115309
Ecotoxicology and environmental safety 2023 Sep 15;263:115309
Activated platelets facilitate hematogenous metastasis of breast cancer by modulating the PDGFR-β/COX-2 axis.
Tang Y, Qian C, Zhou Y, Yu C, Song M, Zhang T, Min X, Wang A, Zhao Y, Lu Y
iScience 2023 Sep 15;26(9):107704
iScience 2023 Sep 15;26(9):107704
Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota.
Li D, Cheng Y, Zeng X, Li Y, Xia Z, Yang X, Ren D
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13363-13375
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13363-13375
Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus.
Hsieh YT, Chen YC, Chou YC, Kuo PY, Yen YT, Tsai HW, Wang CR
Journal of biomedical science 2023 Sep 12;30(1):78
Journal of biomedical science 2023 Sep 12;30(1):78
Protective Effects of ζ-Carotene-like Compounds against Acute UVB-Induced Skin Damage.
Zhang L, Liang S, Zhang Z, Wang K, Cao J, Yao M, Qin L, Qu C, Miao J
International journal of molecular sciences 2023 Sep 12;24(18)
International journal of molecular sciences 2023 Sep 12;24(18)
Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway.
Wei S, Qi F, Wu Y, Liu X
International journal of molecular sciences 2023 Sep 12;24(18)
International journal of molecular sciences 2023 Sep 12;24(18)
GREM1, LRPPRC and SLC39A4 as potential biomarkers of intervertebral disc degeneration: a bioinformatics analysis based on multiple microarray and single-cell sequencing data.
Zhang Z, Huo J, Ji X, Wei L, Zhang J
BMC musculoskeletal disorders 2023 Sep 12;24(1):729
BMC musculoskeletal disorders 2023 Sep 12;24(1):729
Engineered Extracellular Vesicle-Delivered CRISPR/Cas9 for Radiotherapy Sensitization of Glioblastoma.
Liu X, Cao Z, Wang W, Zou C, Wang Y, Pan L, Jia B, Zhang K, Zhang W, Li W, Hao Q, Zhang Y, Zhang W, Xue X, Lin W, Li M, Gu J
ACS nano 2023 Sep 12;17(17):16432-16447
ACS nano 2023 Sep 12;17(17):16432-16447
Robust Osteoconductive β-Tricalcium Phosphate/L-poly(lactic acid) Membrane via Orientation-Strengthening Technology.
Liu S, Chen W, Xiao L, Zhao Z, Liu F, Lu S, Chen C, Luo W, Jiang L, Li Y
ACS biomaterials science & engineering 2023 Sep 11;9(9):5293-5303
ACS biomaterials science & engineering 2023 Sep 11;9(9):5293-5303
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
Dai Y, Wei T, Huang Y, Bei Y, Lin H, Shen Z, Yu L, Yang M, Xu H, He W, Lin Z, Dai H
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
HBx induced upregulation of FATP2 promotes the development of hepatic lipid accumulation.
Lu Y, Yang X, Kuang Q, Wu Y, Tan X, Lan J, Qiang Z, Feng T
Experimental cell research 2023 Sep 1;430(1):113721
Experimental cell research 2023 Sep 1;430(1):113721
m6A-mediated upregulation of miRNA-193a aggravates cardiomyocyte apoptosis and inflammatory response in sepsis-induced cardiomyopathy via the METTL3/ miRNA-193a/BCL2L2 pathway.
Liang L, Liu S, Wu Q, Chen R, Jiang S, Yang Z
Experimental cell research 2023 Sep 1;430(1):113712
Experimental cell research 2023 Sep 1;430(1):113712
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Wang D, Wu S, He J, Sun L, Zhu H, Zhang Y, Liu S, Duan X, Wang Y, Xu T
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
RIG-I promotes cell proliferation in esophageal squamous cell carcinoma by facilitating p21 degradation.
Wang M, Zhang Y, Gao L, Zhang H, Yang Z, Liu J, Shan W, Zeng L, Zhang R, Li Y, Liu J
Medical oncology (Northwood, London, England) 2023 Sep 1;40(10):288
Medical oncology (Northwood, London, England) 2023 Sep 1;40(10):288
S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function.
Zhang J, Chen S, Xiang H, Xiao J, Zhao S, Shu Z, Chai Y, Ouyang J, Liu H, Wang X, Quan Q, Fan J, Gao P, Chen AF, Lu H
Life sciences 2023 Sep 1;328:121853
Life sciences 2023 Sep 1;328:121853
Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis.
Huang Y, Yang W, Yang L, Wang T, Li C, Yu J, Zhang P, Yin Y, Li R, Tao K
Scientific reports 2023 Sep 1;13(1):14359
Scientific reports 2023 Sep 1;13(1):14359
Knockdown of LINC00702 inhibits the growth and induces apoptosis of breast cancer through the Wnt/β-catenin pathway.
Chai D, Yang C, Liu Y, Li H, Lian B, Bai Z, Li J
Heliyon 2023 Oct;9(10):e20651
Heliyon 2023 Oct;9(10):e20651
Prognostic value and immune infiltration of ARMC10 in pancreatic adenocarcinoma via integrated bioinformatics analyses.
Li TH, Qin XH, Wang LQ, Qin C, Zhao BB, Cao HT, Yang XY, Wang YY, Li ZR, Zhou XT, Wang WB
Heliyon 2023 Oct;9(10):e20464
Heliyon 2023 Oct;9(10):e20464
In vitro Assessment of the Effects of Silybin on CYP2B6-mediated Metabolism.
Zhang W, Zhang Y, Wen C, Jiang X, Wang L
Planta medica 2023 Oct;89(13):1195-1203
Planta medica 2023 Oct;89(13):1195-1203
The Comparation of Renal Anti-Senescence Effects and Blood Metabolites between Dapagliflozin and Metformin in Non-Diabetes Environment.
Zeng L, Chen L, Gao F, Li J, Song Y, Wei L, Qu N, Li Y, Jiang H
Advanced biology 2023 Oct;7(10):e2300199
Advanced biology 2023 Oct;7(10):e2300199
Histone deacetylase MrHos3 negatively regulates the production of citrinin and pigments in Monascus ruber.
Liu Q, Zheng Y, Liu B, Tang F, Shao Y
Journal of basic microbiology 2023 Oct;63(10):1128-1138
Journal of basic microbiology 2023 Oct;63(10):1128-1138
Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation.
Kong L, Chu G, Ma W, Liang J, Liu D, Liu Q, Wei X, Jia S, Gu H, He Y, Luo W, Cao S, Zhou X, He R, Yuan Z
Journal of medical genetics 2023 Oct;60(10):939-950
Journal of medical genetics 2023 Oct;60(10):939-950
Evaluating anti-viral effect of Ivermectin on porcine epidemic diarrhea virus and analyzing the related genes and signaling pathway by RNA-seq in vitro.
Wang Y, Qin P, Zhao C, Li Y, Li S, Fan F, Li D, Huang H, Duan H, Yang X, Du W, Li Y
Virology 2023 Oct;587:109877
Virology 2023 Oct;587:109877
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
Zhu C, Yang Y, Song Y, Guo J, Yu G, Tang J, Tang Z
The European journal of neuroscience 2023 Oct;58(7):3605-3617
The European journal of neuroscience 2023 Oct;58(7):3605-3617
Hsa-miR-27b-5p suppresses the osteogenic and odontogenic differentiation of stem cells from human exfoliated deciduous teeth via targeting BMPR1A: An ex vivo study.
Guo R, Gu T, Xiao Y, Xiao T, Liu Q, Li Z, Yu J
International endodontic journal 2023 Oct;56(10):1284-1300
International endodontic journal 2023 Oct;56(10):1284-1300
The therapeutic value of adipose-derived pericyte transplantation after intracerebral hemorrhage in rats.
Zhang X, Zhou Y, Liu Q, Wang F, Fu L, Wei Y, Ye Y, Guo Y
Journal of molecular histology 2023 Oct;54(5):499-508
Journal of molecular histology 2023 Oct;54(5):499-508
Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R.
Zhou WM, Lei ZY, Shi YQ, Gong CY, Kai Z, Wei N, Wang LN, Zhang CJ, Zhang HH
Neurochemical research 2023 Oct;48(10):3099-3112
Neurochemical research 2023 Oct;48(10):3099-3112
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Wang X, Yang J, Wang W, Li Y, Yang Y
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
Interference KRT17 reverses doxorubicin resistance in triple-negative breast cancer cells by Wnt/β-catenin signaling pathway.
Wu L, Ding W, Wang X, Li X, Yang J
Genes & genomics 2023 Oct;45(10):1329-1338
Genes & genomics 2023 Oct;45(10):1329-1338
Inhibiting PI3K/Akt-Signaling Pathway Improves Neurobehavior Changes in Anti-NMDAR Encephalitis Mice by Ameliorating Blood-Brain Barrier Disruption and Neuronal Damage.
Gong Z, Lao D, Wu Y, Li T, Lv S, Mo X, Huang W
Cellular and molecular neurobiology 2023 Oct;43(7):3623-3637
Cellular and molecular neurobiology 2023 Oct;43(7):3623-3637
Hepatic transcriptome delineates the therapeutic effects of Sanren Tang on high-fat diet-induced non-alcoholic fatty liver disease.
Yixiao Y, Hao T, Yi F, Wei L, Jun W, Yiyang HU, Jinghua P
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(6):1092-1102
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(6):1092-1102
Tenofovir disoproxil fumarate mediates neuronal injury by inducing neurotoxicity.
Yang X, Zhang J, Cheng Y, Cui M, Jiang Z, Fan C, Chen J, Qi L, Liu H, Bao D
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2023 Oct;42(10):1195-1205
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2023 Oct;42(10):1195-1205
Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation.
Li T, Niu Z, Yu T, Li J, Lu X, Huang M, Wang Q, Yu X, Feng J, Xu B, Bing D, Li X, Lu L, Liang H, Yang R, Wang B, Shan H
MedComm 2023 Oct;4(5):e348
MedComm 2023 Oct;4(5):e348
Astragaloside IV-mediated inhibition of oxidative stress by upregulation of ghrelin in type 2 diabetes-induced cognitive impairment.
Zhang RH, Cao SS, Shi Y, Wang X, Shi LL, Zhang YH, Han CJ, Wang B, Feng L, Liu JP
Naunyn-Schmiedeberg's archives of pharmacology 2023 Oct;396(10):2637-2650
Naunyn-Schmiedeberg's archives of pharmacology 2023 Oct;396(10):2637-2650
Silymarin ameliorates peritoneal fibrosis by inhibiting the TGF-β/Smad signaling pathway.
Bai Y, Wang L, TingYang, Wang L, Ge W
Naunyn-Schmiedeberg's archives of pharmacology 2023 Oct;396(10):2379-2391
Naunyn-Schmiedeberg's archives of pharmacology 2023 Oct;396(10):2379-2391
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Bian Y, Yin G, Wang G, Liu T, Liang L, Yang X, Zhang W, Tang D
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Chelerythrine chloride inhibits the progression of colorectal cancer by targeting cancer-associated fibroblasts through intervention with WNT10B/β-catenin and TGFβ2/Smad2/3 axis.
Liang D, Liu L, Zheng Q, Zhao M, Zhang G, Tang S, Tang J, Chen N
Phytotherapy research : PTR 2023 Oct;37(10):4674-4689
Phytotherapy research : PTR 2023 Oct;37(10):4674-4689
Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase.
Liu L, Zhang Y, Wang L, Liu Y, Chen H, Hu Q, Xie C, Meng X, Shen X
Phytotherapy research : PTR 2023 Oct;37(10):4587-4606
Phytotherapy research : PTR 2023 Oct;37(10):4587-4606
A peptidic network antibody inhibits both angiogenesis and inflammatory response.
Zhang H, Zhang K, Zhang QS, Wang L, Gao YH, Xu GY, Long D, Wang H, Hu Y
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:715-725
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:715-725
Upregulation of miR-184 and miR-19a-3p induces endothelial dysfunction by targeting AGO2 in Kawasaki disease.
Liao J, Guo X, Fan X, Zhang X, Xu M
Cardiology in the young 2023 Oct;33(10):1962-1966
Cardiology in the young 2023 Oct;33(10):1962-1966
Human-Induced Hepatocytes-Derived Extracellular Vesicles Ameliorated Liver Fibrosis in Mice Via Suppression of TGF-β1/Smad Signaling and Activation of Nrf2/HO-1 Signaling.
Liu W, Wu J, Cao H, Ma C, Wu Z, Tian Y, Ma C, Qiu H, Pan G
Stem cells and development 2023 Oct;32(19-20):638-651
Stem cells and development 2023 Oct;32(19-20):638-651
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration.
Yu C, Ying X, Shahbazi MA, Yang L, Ma Z, Ye L, Yang W, Sun R, Gu T, Tang R, Fan S, Yao S
Biomaterials 2023 Oct;301:122266
Biomaterials 2023 Oct;301:122266
Crosstalk of ferroptosis regulators and tumor immunity in pancreatic adenocarcinoma: novel perspective to mRNA vaccines and personalized immunotherapy.
Shi Y, Wang Y, Dong H, Niu K, Zhang W, Feng K, Yang R, Zhang Y
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1423-1435
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1423-1435
Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway.
Chen G, Zhang H, Sun H, Ding X, Liu G, Yang F, Feng G, Dong X, Zhu Y, Wang X, Wang Y, Li B, Yang L
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1390-1405
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1390-1405
Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways.
Huang JL, Liang L, Xie PE, Sun WL, Wang L, Cai ZW
Experimental and therapeutic medicine 2023 Oct;26(4):484
Experimental and therapeutic medicine 2023 Oct;26(4):484
The 3'‑untranslated region of XB130 regulates its mRNA stability and translational efficiency in non‑small cell lung cancer cells.
Wang Q, Liu L, Gou X, Zhang T, Zhao Y, Xie Y, Zhou J, Liu Y, Song K
Oncology letters 2023 Oct;26(4):427
Oncology letters 2023 Oct;26(4):427
SALL1 promotes proliferation and metastasis and activates phosphorylation of p65 and JUN in colorectal cancer cells.
Yuan J, Li G, Zhong F, Liao J, Zeng Z, Ouyang S, Xie H, Deng Z, Tang H, Ou X
Pathology, research and practice 2023 Oct;250:154827
Pathology, research and practice 2023 Oct;250:154827
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Zhang Y, Peng X, Xue M, Liu J, Shang G, Jiang M, Chen D, Liu B, Wang Y, Jia X, Xu J, Zhang F, Hu Y
Biogerontology 2023 Oct;24(5):813-827
Biogerontology 2023 Oct;24(5):813-827
TMEM175 downregulation participates in impairment of the autophagy related lysosomal dynamics following neonatal hypoxic-ischemic brain injury.
Zhang H, Tian Y, Yu W, Tong D, Ji Y, Qu X, Deng T, Li X, Xu Y
Journal of cellular physiology 2023 Oct;238(10):2512-2527
Journal of cellular physiology 2023 Oct;238(10):2512-2527
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
Zhang L, Li W, Liu X, Guo J, Wu X, Wang J
Experimental eye research 2023 Oct;235:109628
Experimental eye research 2023 Oct;235:109628
EGFR suppression contributes to growth inhibitory activity of G-quadruplex ligands in non-small cell lung cancers.
Lu K, Wang HC, Tu YC, Lou PJ, Chang TC, Lin JJ
Biochemical pharmacology 2023 Oct;216:115788
Biochemical pharmacology 2023 Oct;216:115788
Sulforaphene suppresses RANKL-induced osteoclastogenesis and LPS-induced bone erosion by activating Nrf2 signaling pathway.
Yao H, Du Y, Jiang B, Liao Y, Zhao Y, Yin M, Li T, Sheng Y, Ji Y, Du M
Free radical biology & medicine 2023 Oct;207:48-62
Free radical biology & medicine 2023 Oct;207:48-62
Metformin Promotes Proliferation of Mouse Female Germline Stem Cells by Histone Acetylation Modification of Traf2.
Chen J, Wang L, Tian GG, Wang X, Li X, Wu J
Stem cell reviews and reports 2023 Oct;19(7):2329-2340
Stem cell reviews and reports 2023 Oct;19(7):2329-2340
Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway.
Zhang L, Luo P, Mao X, Sun J, Wei J, Yang Y, Zhang Y, Jiang X
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119509
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119509
Intermittent fasting alleviates type 1 diabetes-induced cognitive dysfunction by improving the frontal cortical metabolic disorder.
Xiong F, Jiang K, Wu Y, Lou C, Ding C, Zhang W, Zhang X, Li C, Zheng H, Gao H
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166725
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166725
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
Bu X, Zhang J, Sun H, Wang W, Ma X, Sun L
Journal of dental sciences 2023 Oct;18(4):1685-1692
Journal of dental sciences 2023 Oct;18(4):1685-1692
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Li W, Xu L, Cao J, Ge J, Liu X, Liu P, Teng Y, Wang S, Sun Y, Liu M, Tian L
Immunology 2023 Oct;170(2):253-269
Immunology 2023 Oct;170(2):253-269
Cocktail of three isoquinoline alkaloids derived from Glaucium grandiflorum Boiss. & A. Huet subsp. refractum (Nábelek) Mory inhibits the production of LPS-induced ROS, pro-inflammatory cytokines, and mediators through the down-regulation of p38 MAPK in BV-2 cells.
Nigdelioglu Dolanbay S, Şirin S, Aslim B
Fitoterapia 2023 Oct;170:105652
Fitoterapia 2023 Oct;170:105652
High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast.
Xie D, Wang Z, Sun B, Qu L, Zeng M, Feng L, Guo M, Wang G, Hao J, Zhou G
Frontiers of medicine 2023 Oct;17(5):907-923
Frontiers of medicine 2023 Oct;17(5):907-923
Regulatory mechanism of CaMKII δ mediated by RIPK3 on myocardial fibrosis and reversal effects of RIPK3 inhibitor GSK'872.
Zhang J, Cao J, Qian J, Gu X, Zhang W, Chen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115380
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115380
Caffeic acid's role in mitigating polycystic ovary syndrome by countering apoptosis and ER stress triggered by oxidative stress.
Chiang YF, Lin IC, Huang KC, Chen HY, Ali M, Huang YJ, Hsia SM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115327
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115327
Photocurable 3D-Printed PMBG/TCP Scaffold Coordinated with PTH (1-34) Bidirectionally Regulates Bone Homeostasis to Accelerate Bone Regeneration.
Ren Y, Kong W, Liu Y, Yang X, Xu X, Qiang L, Mi X, Zhang C, Niu H, Wang C, Wang J
Advanced healthcare materials 2023 Oct;12(25):e2300292
Advanced healthcare materials 2023 Oct;12(25):e2300292
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Yang Z, Wu G, Zhao J, Shi G, Zhou J, Zhou X
Cancer medicine 2023 Oct;12(19):19850-19865
Cancer medicine 2023 Oct;12(19):19850-19865
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Xanthatin suppresses pancreatic cancer cell growth via the ROS/RBL1 signaling pathway: In vitro and in vivo insights.
Geng Y, Liu P, Xie Y, Liu Y, Zhang X, Hou X, Zhang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155004
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155004
Systemic pharmacology reveal the mechanism by which the Qiangjin Zhuanggu Qufeng mixture inhibits LPS-induced pyroptosis of rat nucleus pulposus cells.
Wang D, Zhang L, He D, Zhang Y, Bao J, Gao W, Cheng W, Zhu C, Jin H, Zhang W, Zhu H, Pan H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154998
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154998
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
Zhang W, Sun L, Gao H, Wang S
International journal of experimental pathology 2023 Oct;104(5):258-268
International journal of experimental pathology 2023 Oct;104(5):258-268
Protective effect of TNIP2 on the inflammatory response of microglia after spinal cord injury in rats.
Fu J, Wu C, Xu G, Zhang J, Chen J, Chen C, Hong H, Xue P, Jiang J, Huang J, Ji C, Cui Z
Neuropeptides 2023 Oct;101:102351
Neuropeptides 2023 Oct;101:102351
The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons.
Wang Y, Hong Q, Xia Y, Zhang Z, Wen B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301367
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301367
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
Tong Sai granule improves AECOPD via regulation of MAPK-SIRT1-NF-κB pathway and cellular senescence alleviation.
Tao L, Lu X, Fu Z, Tian Y, Liu X, Li J, Zhao P
Journal of ethnopharmacology 2023 Oct 5;314:116622
Journal of ethnopharmacology 2023 Oct 5;314:116622
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer.
Zhou A, Zhou C, Wang D, Qian M, Huang L
Journal of ethnopharmacology 2023 Oct 5;314:116576
Journal of ethnopharmacology 2023 Oct 5;314:116576
Discovery of novel thymidylate synthase (TS) inhibitors that influence cancer angiogenesis and metabolic reprogramming in NSCLC cells.
Dong G, Li YH, Guo JS, Lin QQ, Deng MY, Xue WH, Li XY, Meng FH
European journal of medicinal chemistry 2023 Oct 5;258:115600
European journal of medicinal chemistry 2023 Oct 5;258:115600
Proteostasis is differentially modulated by inhibition of translation initiation or elongation.
Clay KJ, Yang Y, Clark C, Petrascheck M
eLife 2023 Oct 5;12
eLife 2023 Oct 5;12
GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion.
Zhao C, Liang F, Ye M, Wu S, Qin Y, Zhao L, Zhang L, He J, Cen L, Lin F
Cell death discovery 2023 Oct 4;9(1):368
Cell death discovery 2023 Oct 4;9(1):368
Synergistic induction of apoptosis in liver cancer cells: exploring the combined potential of doxorubicin and XL-888.
Kaplan Ö
Medical oncology (Northwood, London, England) 2023 Oct 4;40(11):318
Medical oncology (Northwood, London, England) 2023 Oct 4;40(11):318
A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Kumar A, Gok MO, Nguyen KN, Reese ML, Wideman JG, Muñoz-Gómez SA, Friedman JR
bioRxiv : the preprint server for biology 2023 Oct 4;
bioRxiv : the preprint server for biology 2023 Oct 4;
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.
Zhao Y, Sui L, Wu P, Li L, Liu L, Ma B, Wang W, Chi H, Wang Z-D, Wei Z, Hou Z, Zhang K, Niu J, Jin N, Li C, Zhao J, Wang G, Liu Q
Journal of virology 2023 Oct 31;97(10):e0102823
Journal of virology 2023 Oct 31;97(10):e0102823
Chick chorioallantoic membrane model to investigate role of migrasome in angiogenensis.
Zhang C, He H, Yin S, Gao M, Yu L
Biophysics reports 2023 Oct 31;9(5):241-254
Biophysics reports 2023 Oct 31;9(5):241-254
Anti-inflammatory effect of Lactiplantibacillus plantarum T1 cell-free supernatants through suppression of oxidative stress and NF-κB- and MAPK-signaling pathways.
Hao R, Liu Q, Wang L, Jian W, Cheng Y, Zhang Q, Hayer K, Kamarudin Raja Idris R, Zhang Y, Lu H, Tu Z
Applied and environmental microbiology 2023 Oct 31;89(10):e0060823
Applied and environmental microbiology 2023 Oct 31;89(10):e0060823
α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity.
Horvath JD, Casas M, Kutchukian C, Sánchez SC, Pergande MR, Cologna SM, Simó S, Dixon RE, Dickson EJ
Cell reports 2023 Oct 31;42(10):113244
Cell reports 2023 Oct 31;42(10):113244
Enzymolysis-based RNA pull-down identifies YTHDC2 as an inhibitor of antiviral innate response.
Zhu J, Liu S, Fang J, Cui Z, Wang B, Wang Y, Liu L, Wang Q, Cao X
Cell reports 2023 Oct 31;42(10):113192
Cell reports 2023 Oct 31;42(10):113192
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Li F, Zhang Z, Bai Y, Che Q, Cao H, Guo J, Su Z
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance.
Kong C, Qu X, Liu M, Xu W, Chen D, Zhang Y, Zhang S, Zhu F, Liu Z, Li J, Huang C, Wang C
Nature communications 2023 Oct 27;14(1):6860
Nature communications 2023 Oct 27;14(1):6860
BMP9 functions as a negative regulator in the myogenic differentiation of primary mouse myoblasts.
Lu X, Li L, Wu N, Chen W, Hong S, Xu M, Ding Y, Gao Y
Bioscience, biotechnology, and biochemistry 2023 Oct 25;87(11):1255-1264
Bioscience, biotechnology, and biochemistry 2023 Oct 25;87(11):1255-1264
Chlorogenic Acid from Burdock Roots Ameliorates Oleic Acid-Induced Steatosis in HepG2 Cells through AMPK/ACC/CPT-1 Pathway.
Ma K, Sheng W, Song X, Song J, Li Y, Huang W, Liu Y
Molecules (Basel, Switzerland) 2023 Oct 25;28(21)
Molecules (Basel, Switzerland) 2023 Oct 25;28(21)
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma.
Li H, Guo H, Huang Q, Wang S, Li X, Qiu M
Respiratory research 2023 Oct 25;24(1):252
Respiratory research 2023 Oct 25;24(1):252
BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas.
Gao L, Ye Z, Peng S, Lei P, Song P, Li Z, Zhou L, Hua Q, Cheng L, Wei H, Liu J, Cai Q
Aging 2023 Oct 25;15(20):11611-11638
Aging 2023 Oct 25;15(20):11611-11638
BMP7 alleviates trigeminal neuralgia by reducing oligodendrocyte apoptosis and demyelination.
Chen K, Wei X, Wang R, Yang L, Zou D, Wang Y
The journal of headache and pain 2023 Oct 24;24(1):143
The journal of headache and pain 2023 Oct 24;24(1):143
A Therapeutic DNA Vaccine Targeting HPV16 E7 in Combination with Anti-PD-1/PD-L1 Enhanced Tumor Regression and Cytotoxic Immune Responses.
Han X, Gao Z, Cheng Y, Wu S, Chen J, Zhang W
International journal of molecular sciences 2023 Oct 23;24(20)
International journal of molecular sciences 2023 Oct 23;24(20)
Effects of Insulin on Proliferation, Apoptosis, and Ferroptosis in Primordial Germ Cells via PI3K-AKT-mTOR Signaling Pathway.
Ye L, Liu X, Jin K, Niu Y, Zuo Q, Song J, Han W, Chen G, Li B
Genes 2023 Oct 22;14(10)
Genes 2023 Oct 22;14(10)
Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis.
Liu Y, Cui H, Mei C, Cui M, He Q, Wang Q, Li D, Song Y, Li J, Chen S, Zhu C
Cell death & disease 2023 Oct 21;14(10):694
Cell death & disease 2023 Oct 21;14(10):694
TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC.
Huang N, Li P, Sun X, Tong L, Dong X, Zhang X, Duan J, Sheng X, Xin H
NPJ breast cancer 2023 Oct 20;9(1):85
NPJ breast cancer 2023 Oct 20;9(1):85
[High expression of secretogranin II increases oxaliplatin resistance of colorectal cancer cells].
Deng J, Pan T, Zhou G, Gao Y, Peng W, Wei W, Lü C
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Oct 20;43(10):1657-1664
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Oct 20;43(10):1657-1664
Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling.
Huang J, Xu ZF, Liu F, Song AN, Su H, Zhang C
iScience 2023 Oct 20;26(10):107940
iScience 2023 Oct 20;26(10):107940
CircMAPK9 promotes adipogenesis through modulating hsa-miR-1322/FTO axis in obesity.
Chen S, Song P, Wang Y, Wang Z, Xue J, Jiang Y, Zhou Y, Zhao J, Tang L
iScience 2023 Oct 20;26(10):107756
iScience 2023 Oct 20;26(10):107756
Expression profiles and function prediction of tRNA-derived fragments in glioma.
Wei D, Niu B, Zhai B, Liu XB, Yao YL, Liang CC, Wang P
BMC cancer 2023 Oct 20;23(1):1015
BMC cancer 2023 Oct 20;23(1):1015
IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions.
Yan C, Chen J, Tang H, Deng C, Zhang Q, Wang X
Journal of inflammation (London, England) 2023 Oct 20;20(1):34
Journal of inflammation (London, England) 2023 Oct 20;20(1):34
Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses.
Yang ZQ, Guo LY, Xiao KW, Zhang C, Wu MH, Yan FF, Cai L
Aging 2023 Oct 20;15(20):11412-11447
Aging 2023 Oct 20;15(20):11412-11447
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D(2) Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
Sánchez-Soto M, Boldizsar NM, Schardien KA, Madaras NS, Willette BKA, Inbody LR, Dasaro C, Moritz AE, Drube J, Haider RS, Free RB, Hoffman C, Sibley DR
Biomolecules 2023 Oct 20;13(10)
Biomolecules 2023 Oct 20;13(10)
High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression.
Wei P, Lin D, Luo C, Zhang M, Deng B, Cui K, Chen Z
Scientific reports 2023 Oct 20;13(1):17910
Scientific reports 2023 Oct 20;13(1):17910
Effects of Cinnamon Powder on Glucose Metabolism in Diabetic Mice and the Molecular Mechanisms.
Liu Y, Liu F, Xing D, Wang W, Yang Q, Liao S, Li E, Pang D, Zou Y
Foods (Basel, Switzerland) 2023 Oct 20;12(20)
Foods (Basel, Switzerland) 2023 Oct 20;12(20)
African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation.
Chen Q, Li L, Liu L, Liu Z, Guo S, Tan C, Chen H, Wang X
Virus research 2023 Oct 2;335:199190
Virus research 2023 Oct 2;335:199190
Identification of Potential Mechanisms of Rk1 Combination with Rg5 in the Treatment of Type II Diabetes Mellitus by Integrating Network Pharmacology and Experimental Validation.
Liu Y, Zhang J, An C, Liu C, Zhang Q, Ding H, Ma S, Xue W
International journal of molecular sciences 2023 Oct 2;24(19)
International journal of molecular sciences 2023 Oct 2;24(19)
CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis.
Zhou X, Meng F, Xiao L, Shen H
BMC medical genomics 2023 Oct 2;16(1):228
BMC medical genomics 2023 Oct 2;16(1):228
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Cai Y, Sun H, Song X, Zhao J, Xu D, Liu M
Aging 2023 Oct 19;15(20):11471-11488
Aging 2023 Oct 19;15(20):11471-11488
miR-103-3p Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2.
He Y, Yang P, Yuan T, Zhang L, Yang G, Jin J, Yu T
International journal of molecular sciences 2023 Oct 18;24(20)
International journal of molecular sciences 2023 Oct 18;24(20)
Comprehensive Transcriptomic Profiling of m6A Modification in Age-Related Hearing Loss.
Feng M, Zhou X, Hu Y, Zhang J, Yang T, Chen Z, Yuan W
Biomolecules 2023 Oct 18;13(10)
Biomolecules 2023 Oct 18;13(10)
The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma.
Li K, Chen J, Zhang C, Cheng M, Chen S, Song W, Yang C, Ling R, Chen Z, Wang X, Xiong G, Ma J, Zhu Y, Yuan Q, Liu Q, Peng L, Chen Q, Chen D
The Journal of clinical investigation 2023 Oct 16;133(20)
The Journal of clinical investigation 2023 Oct 16;133(20)
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
Zheng X, Su F, Lei M, Li J, Zhang C, Zhang Y, Wei M, Li W, Chen S, Liu Y, Gao Q, Hao L
European journal of pharmacology 2023 Oct 15;957:175969
European journal of pharmacology 2023 Oct 15;957:175969
Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.
Zhang J, Dong Y, Liu X, Jin H, Wang S, An N, Wang L
International journal of pharmaceutics 2023 Oct 15;645:123389
International journal of pharmaceutics 2023 Oct 15;645:123389
Expression of TRPM8 in sheep reproductive tissues and brain areas important for the expression of reproductive behavior.
Sutton CM, Ziegler RL, Austin KJ, Alexander BM
Physiology & behavior 2023 Oct 15;270:114304
Physiology & behavior 2023 Oct 15;270:114304
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.
Qiu C, Shen X, Lu H, Chen Y, Xu C, Zheng P, Xia Y, Wang J, Zhang Y, Li S, Zou P, Cui R, Chen J
Cell death discovery 2023 Oct 13;9(1):375
Cell death discovery 2023 Oct 13;9(1):375
Development of a Rare Earth Nanoprobe Enables In Vivo Real-Time Detection of Sentinel Lymph Node Metastasis of Breast Cancer Using NIR-IIb Imaging.
Zhu YY, Song L, Zhang YQ, Liu WL, Chen WL, Gao WL, Zhang LX, Wang JZ, Ming ZH, Zhang Y, Zhang GJ
Cancer research 2023 Oct 13;83(20):3428-3441
Cancer research 2023 Oct 13;83(20):3428-3441
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Wu Q, Liang Z, Jiang J, Feng X, Liu J, Zhang Z, Wang H, Wang N, Gou Y, Li Z, Cao Y
Cell death & disease 2023 Oct 11;14(10):668
Cell death & disease 2023 Oct 11;14(10):668
Matrix stiffness induces Drp1-mediated mitochondrial fission through Piezo1 mechanotransduction in human intervertebral disc degeneration.
Ke W, Wang B, Liao Z, Song Y, Li G, Ma L, Wang K, Li S, Hua W, Yang C
Journal of translational medicine 2023 Oct 10;21(1):711
Journal of translational medicine 2023 Oct 10;21(1):711
SNIP1 reduces extracellular matrix degradation and inflammation via inhibiting the NF-κB signaling pathway in osteoarthritis.
Chen Y, Guo W, Lu W, Guo X, Gao W, Yin Z
Archives of biochemistry and biophysics 2023 Oct 1;747:109764
Archives of biochemistry and biophysics 2023 Oct 1;747:109764
Metformin combined with glucose starvation synergistically suppress triple-negative breast cancer by enhanced unfolded protein response.
Li Y, Zhang Q, Yang J, He W, Jiang Y, Chen Y, Wang Y
Biochemical and biophysical research communications 2023 Oct 1;675:146-154
Biochemical and biophysical research communications 2023 Oct 1;675:146-154
Dapagliflozin suppress endoplasmic reticulum stress mediated apoptosis of chondrocytes by activating Sirt1.
Liu Z, Huang J, Wang X, Deng S, Zhou J, Gong Z, Li X, Wang Y, Yang J, Hu Y
Chemico-biological interactions 2023 Oct 1;384:110724
Chemico-biological interactions 2023 Oct 1;384:110724
Chronic exposure to low-dose deltamethrin can lead to colon tissue injury through PRDX1 inactivation-induced mitochondrial oxidative stress injury and gut microbial dysbiosis.
Ma R, Sun T, Wang X, Ren K, Min T, Xie X, Wang D, Li K, Zhang Y, Zhu K, Mo C, Dang C, Yang Y, Zhang H
Ecotoxicology and environmental safety 2023 Oct 1;264:115475
Ecotoxicology and environmental safety 2023 Oct 1;264:115475
Aluminum exposure induces central nervous system impairment via activating NLRP3-medicated pyroptosis pathway.
Hao W, Zhu X, Liu Z, Song Y, Wu S, Lu X, Yang J, Jin C
Ecotoxicology and environmental safety 2023 Oct 1;264:115401
Ecotoxicology and environmental safety 2023 Oct 1;264:115401
Endoplasmic reticulum-mitochondrial calcium transport contributes to soft extracellular matrix-triggered mitochondrial dynamics and mitophagy in breast carcinoma cells.
Chen Y, Li P, Chen X, Yan R, Zhang Y, Wang M, Qin X, Li S, Zheng C, You F, Li T, Liu Y
Acta biomaterialia 2023 Oct 1;169:192-208
Acta biomaterialia 2023 Oct 1;169:192-208
Clearance of Stress-Induced Premature Senescent Cells Alleviates the Formation of Abdominal Aortic Aneurysms.
Xie J, Tang Z, Chen Q, Jia X, Li C, Jin M, Wei G, Zheng H, Li X, Chen Y, Liao W, Liao Y, Bin J, Huang S
Aging and disease 2023 Oct 1;14(5):1778-1798
Aging and disease 2023 Oct 1;14(5):1778-1798
Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression.
Song Z, Cao Q, Guo B, Zhao Y, Li X, Lou N, Zhu C, Luo G, Peng S, Li G, Chen K, Wang Y, Ruan H, Guo Y
Aging and disease 2023 Oct 1;14(5):1757-1774
Aging and disease 2023 Oct 1;14(5):1757-1774
Protective effect of GLP-1 analog liraglutide on podocytes in mice with diabetic nephropathy.
Shi S, Chen X, Yu W, Ke X, Ma T
Endocrine connections 2023 Oct 1;12(10)
Endocrine connections 2023 Oct 1;12(10)
Moutai Distiller's grains Polyphenol extracts and rutin alleviate DSS-induced colitis in mice: Modulation of gut microbiota and intestinal barrier function （R2）.
Chen JH, Zhao CL, Li YS, Yang YB, Luo JG, Zhang C, Wang L
Heliyon 2023 Nov;9(11):e22186
Heliyon 2023 Nov;9(11):e22186
The extract from Portulaca oleracea L. rehabilitates skin photoaging via adjusting miR-138-5p/Sirt1-mediated inflammation and oxidative stress.
Qu L, Wang F, Ma X
Heliyon 2023 Nov;9(11):e21955
Heliyon 2023 Nov;9(11):e21955
HuangQi ChiFeng decoction maintains gut microbiota and bile acid homeostasis through FXR signaling to improve atherosclerosis.
Fu J, Liang Y, Shi Y, Yu D, Wang Y, Chen P, Liu S, Lu F
Heliyon 2023 Nov;9(11):e21935
Heliyon 2023 Nov;9(11):e21935
FBXL19 promotes malignant behaviours by activating MAPK signalling and negatively correlates with prognosis in hepatocellular carcinoma.
Xun M, Wang J, Xie Q, Peng B, Li Z, Guo Z, Zeng Y, Su H, Yao M, Liao L, Li Y, Yuan G, Chen S, He S
Heliyon 2023 Nov;9(11):e21771
Heliyon 2023 Nov;9(11):e21771
Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS- induced depression-like behaviors through downregulation of α2δ-1.
Jiang C, Wang C, Qu W, Wang Y, Wang H, Wei X, Wang M, He Q, Wang Y, Yuan L, Gao Y
Heliyon 2023 Nov;9(11):e21743
Heliyon 2023 Nov;9(11):e21743
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
Sun W, Yue J, Xu T, Cui Y, Huang D, Shi H, Xiong J, Sun W, Yi Q
Heliyon 2023 Nov;9(11):e21282
Heliyon 2023 Nov;9(11):e21282
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
Zhang H, Gong J, Zhang S, Luo L, Luo C, Bi K, Wang L, Kan X, Tian Z, Wang X
Heliyon 2023 Nov;9(11):e21235
Heliyon 2023 Nov;9(11):e21235
BMSCs alleviate liver cirrhosis by regulating Fstl1/Wnt/β-Catenin signaling pathway.
Zhangdi H, Geng X, Li N, Xu R, Hu Y, Liu J, Zhang X, Qi J, Tian Y, Qiu J, Huang S, Cang X, Jin S
Heliyon 2023 Nov;9(11):e21010
Heliyon 2023 Nov;9(11):e21010
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
Ge M, Zhu J, Yi K, Chen Y, Cao W, Wang M, Xie C, Li X, Geng S, Wu J, Zhong C, Cao H, Jiang Z, Han H
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
Gao X, You Z, Huang C, Liu Z, Tan Z, Li J, Liu Y, Liu X, Wei F, Fan Z, Qi S, Sun J
Molecular neurobiology 2023 Nov;60(11):6676-6688
Molecular neurobiology 2023 Nov;60(11):6676-6688
Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.
Gong M, Jia J
Molecular neurobiology 2023 Nov;60(11):6598-6612
Molecular neurobiology 2023 Nov;60(11):6598-6612
Different Chronic Stress Paradigms Converge on Endogenous TDP43 Cleavage and Aggregation.
Candelise N, Caissutti D, Zenuni H, Nesci V, Scaricamazza S, Salvatori I, Spinello Z, Mattei V, Garofalo T, Ferri A, Valle C, Misasi R
Molecular neurobiology 2023 Nov;60(11):6346-6361
Molecular neurobiology 2023 Nov;60(11):6346-6361
Ketamine counteracts sevoflurane-induced depressive-like behavior and synaptic plasticity impairments through the adenosine A2A receptor/ERK pathway in rats.
Yu W, Wu Z, Li X, Ding M, Xu Y, Zhao P
Molecular neurobiology 2023 Nov;60(11):6160-6175
Molecular neurobiology 2023 Nov;60(11):6160-6175
Macrophage Sult2b1 promotes pathological neovascularization in age-related macular degeneration.
Wang Y, Liu Y, Wang Y, Wu Y, Chen Z, Wang F, Wan X, Wang F, Sun X
Life science alliance 2023 Nov;6(11)
Life science alliance 2023 Nov;6(11)
Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway.
Wei G, Li C, Jia X, Xie J, Tang Z, Jin M, Chen Q, Sun Y, He S, Li X, Chen Y, Zheng H, Liao W, Liao Y, Bin J, Huang S
Journal of advanced research 2023 Nov;53:199-218
Journal of advanced research 2023 Nov;53:199-218
Pseudolaric acid B induces apoptosis associated with the mitochondrial and PI3K/AKT/mTOR pathways in triple‑negative breast cancer.
Yang K, Wang JQ, Li K, Chen SN, Yu F
Oncology reports 2023 Nov;50(5)
Oncology reports 2023 Nov;50(5)
Pb inhibited C2C12 myoblast differentiation by regulating HDAC2.
Gu X, Shen N, Huang C, Wang HL
Toxicology 2023 Nov;499:153639
Toxicology 2023 Nov;499:153639
LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90.
Huang S, Hou D, Zhang L, Pei C, Liang J, Li J, Yang G, Yu D
Neurochemical research 2023 Nov;48(11):3457-3471
Neurochemical research 2023 Nov;48(11):3457-3471
Melatonin attenuates cholestatic liver injury via inhibition of the inflammatory response.
Tan Y, Zhao N, Xie Q, Xu Z, Chai J, Zhang X, Li Y
Molecular and cellular biochemistry 2023 Nov;478(11):2527-2537
Molecular and cellular biochemistry 2023 Nov;478(11):2527-2537
MicroRNA-122-5p alleviates endometrial fibrosis via inhibiting the TGF-β/SMAD pathway in Asherman's syndrome.
Chen S, Ma Y, Qiu X, Liu M, Zhang P, Wei C, Dai Y, Ge L, Zhu H, Zhang Y, Zhang J, Lin X
Reproductive biomedicine online 2023 Nov;47(5):103253
Reproductive biomedicine online 2023 Nov;47(5):103253
Capsaicin functions as a selective degrader of STAT3 to enhance host resistance to viral infection.
Zhang MQ, Jia X, Cheng CQ, Wang YX, Li YY, Kong LD, Li QQ, Xie F, Yu YL, He YT, Dong QT, Jia ZH, Wang Y, Xu AL
Acta pharmacologica Sinica 2023 Nov;44(11):2253-2264
Acta pharmacologica Sinica 2023 Nov;44(11):2253-2264
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.
Zhu XX, Wang X, Jiao SY, Liu Y, Shi L, Xu Q, Wang JJ, Chen YE, Zhang Q, Song YT, Wei M, Yu BQ, Fielitz J, Gonzalez FJ, Du J, Qu AJ
Acta pharmacologica Sinica 2023 Nov;44(11):2184-2200
Acta pharmacologica Sinica 2023 Nov;44(11):2184-2200
Human amnion-derived mesenchymal stem cells improve subclinical hypothyroidism by immunocompetence mediating apoptosis inhibition on thyroid cells in aged mice.
Li C, Rui Q, Dong X, Ning S, Zhou J, Wu H, Jiang C, Cui Y, Liu J, Jiang J, Qin L
Cell and tissue research 2023 Nov;394(2):309-323
Cell and tissue research 2023 Nov;394(2):309-323
Role of interleukin-36γ induced by ultraviolet radiation in chronic actinic dermatitis.
Wang L, Tu Y, Wu W, Tu Y, Yang Z, Chai Y, Yang X, He L
Photodermatology, photoimmunology & photomedicine 2023 Nov;39(6):598-606
Photodermatology, photoimmunology & photomedicine 2023 Nov;39(6):598-606
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Xu W, Li F, Zhu L, Cheng M, Cheng Y
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
The novel peptide DR4penA attenuates the bleomycin- and paraquat-induced pulmonary fibrosis by suppressing the TGF-β/Smad signaling pathway.
Wang D, Deng B, Cheng L, Li J, Guo X, Zhang J, Zhang X, Su P, Li G, Miao X, Yang W, Xie J, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23225
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23225
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
Engineering CAR-NK cell derived exosome disguised nano-bombs for enhanced HER2 positive breast cancer brain metastasis therapy.
Tao B, Du R, Zhang X, Jia B, Gao Y, Zhao Y, Liu Y
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:692-706
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:692-706
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1α pathway.
Zeng J, Wang Y, Zhu M, Wu M, Zhou Y, Wang Q, Xu Y, Lin F, Wang J, Li Y, Liang S, Wang Z, Xie L, Liu X
The FEBS journal 2023 Nov;290(22):5395-5410
The FEBS journal 2023 Nov;290(22):5395-5410
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Yang Y, Zhu J, Chiba Y, Fukumoto S, Qin M, Wang X
Oral diseases 2023 Nov;29(8):3654-3664
Oral diseases 2023 Nov;29(8):3654-3664
Periplaneta americana extract promotes osteoblast differentiation of human alveolar bone marrow mesenchymal stem cells.
Xu J, Zhao B, Lin W, Liu Y, Zhang X, Wang Y, Zhang Y, Liu W, Seriwatanachai D, Yuan Q
Oral diseases 2023 Nov;29(8):3540-3550
Oral diseases 2023 Nov;29(8):3540-3550
UBE2C promotes malignancy of cutaneous squamous cell carcinoma.
Luo R, Bai R, Guo J, Xian N, Zheng Y
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2023 Nov;29(11):e13526
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2023 Nov;29(11):e13526
Optimized infrared photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (IR-PAR-CLIP) protocol identifies novel IGF2BP3-interacting RNAs in colon cancer cells.
Anisimova AS, Karagöz GE
RNA (New York, N.Y.) 2023 Nov;29(11):1818-1836
RNA (New York, N.Y.) 2023 Nov;29(11):1818-1836
Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line chick.
Tian G, Huang C, Li Z, Lu Z, Feng C, Zhuang Y, Li G, Liu P, Hu G, Gao X, Guo X
Veterinary microbiology 2023 Nov;286:109891
Veterinary microbiology 2023 Nov;286:109891
Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.
Wang Y, Wen Q, Chen R, Gan Z, Huang X, Wang P, Cao X, Zhao N, Yang Z, Yan J
Journal of cellular and molecular medicine 2023 Nov;27(22):3614-3627
Journal of cellular and molecular medicine 2023 Nov;27(22):3614-3627
SIRT6 mediated histone H3K9ac deacetylation involves myocardial remodelling through regulating myocardial energy metabolism in TAC mice.
Wu S, Zhang J, Peng C, Ma Y, Tian X
Journal of cellular and molecular medicine 2023 Nov;27(22):3451-3464
Journal of cellular and molecular medicine 2023 Nov;27(22):3451-3464
Avicularin alleviates acute liver failure by regulation of the TLR4/MyD88/NF-κB and Nrf2/HO-1/GPX4 pathways to reduce inflammation and ferroptosis.
Shi P, Zhu W, Fu J, Liang A, Zheng T, Wen Z, Wu X, Peng Y, Yuan S, Wu X
Journal of cellular and molecular medicine 2023 Nov;27(21):3326-3338
Journal of cellular and molecular medicine 2023 Nov;27(21):3326-3338
Extracellular vesicles from bone marrow mesenchymal stem cells alleviate osteoporosis in mice through USP7-mediated YAP1 protein stability and the Wnt/β-catenin pathway.
Wang X, Zou C, Hou C, Bian Z, Jiang W, Li M, Zhu L
Biochemical pharmacology 2023 Nov;217:115829
Biochemical pharmacology 2023 Nov;217:115829
Selenium Deficiency via the ROS/NLRP3/IL-1β Signaling Pathway Leads to Pyroptosis Injury in Pig Spleen.
Song L, Jiang Z, Zhang X, Song Y, Xing Y, Wang G
Biological trace element research 2023 Nov;201(11):5192-5200
Biological trace element research 2023 Nov;201(11):5192-5200
Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils.
Jiang X, Xiao X, Li H, Gong Y, Wang M, Yang H, Zhao L, Jiang Y, Wei Y, Zhao C, Li J, Chen Y, Feng S, Deng H, Ma S, Xu Y, Liu Y, Tsokos GC, Jiang M, Zhang X
Cellular & molecular immunology 2023 Nov;20(11):1339-1351
Cellular & molecular immunology 2023 Nov;20(11):1339-1351
Sulforaphane alleviates the meiosis defects induced by 3-nitropropionic acid in mouse oocytes.
Li WJ, Zhang X, Shen M, Liu HL, Ding LR
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114083
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114083
In vitro acne disease model from inertial focusing effect for studying the interactions between sebocyte glands and macrophages.
Tang T, Xu Y, Wang L, Zhang P
Biotechnology journal 2023 Nov;18(11):e2300108
Biotechnology journal 2023 Nov;18(11):e2300108
High-intensity swimming alleviates nociception and neuroinflammation in a mouse model of chronic post-ischemia pain by activating the resolvin E1-chemerin receptor 23 axis in the spinal cord.
Jia X, Li Z, Shen X, Zhang Y, Zhang L, Zhang L
Neural regeneration research 2023 Nov;18(11):2535-2544
Neural regeneration research 2023 Nov;18(11):2535-2544
Dl-3-n-butylphthalide exerts neuroprotective effects by modulating hypoxia-inducible factor 1-alpha ubiquitination to attenuate oxidative stress-induced apoptosis.
Li S, Zhao J, Xi Y, Ren J, Zhu Y, Lu Y, Dong D
Neural regeneration research 2023 Nov;18(11):2424-2428
Neural regeneration research 2023 Nov;18(11):2424-2428
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
Shen G, Xiao H, Huang S, Yuan X, Rongrong Z, Ma Y, Qin X
Neurochemistry international 2023 Nov;170:105546
Neurochemistry international 2023 Nov;170:105546
Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2.
Ma X, Zhang L, Gao F, Jia W, Li C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115501
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115501
Keratinocyte derived HMGB1 aggravates psoriasis dermatitis via facilitating inflammatory polarization of macrophages and hyperproliferation of keratinocyte.
Chen J, Fu Y, Xiong S
Molecular immunology 2023 Nov;163:1-12
Molecular immunology 2023 Nov;163:1-12
Anti-resorption role of low-intensity pulsed ultrasound (LIPUS) during large-scale bone reconstruction using porous titanium alloy scaffolds through inhibiting osteoclast differentiation.
Luo L, Cao H, Zhou L, Zhang G, Wu L
Biomaterials advances 2023 Nov;154:213634
Biomaterials advances 2023 Nov;154:213634
STAT1 suppresses the transcriptional activity of TRIM21 in gastric cancer.
Huo C, Gu Y, Wang D, Zhang X, Tang F, Zhao B, Liu T, He W, Li Y
Journal of cancer research and clinical oncology 2023 Nov;149(17):15335-15348
Journal of cancer research and clinical oncology 2023 Nov;149(17):15335-15348
PINK1-mediated mitophagy induction protects against preeclampsia by decreasing ROS and trophoblast pyroptosis.
Sun Y, Lv D, Xie Y, Xu H, Li X, Li F, Fan Y, Zhang X, Zhang Y, Chen S, He M, Deng D
Placenta 2023 Nov;143:1-11
Placenta 2023 Nov;143:1-11
Abamectin induced brain and liver toxicity in carp: The healing potential of silybin and potential molecular mechanisms.
Wu X, Xin Y, Ma Y, Ping K, Li Q, Sun Y, Hu Z, Dong J
Fish & shellfish immunology 2023 Nov;142:109152
Fish & shellfish immunology 2023 Nov;142:109152
Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors.
Long Z, Zuo Y, Li R, Le Y, Dong Y, Yan L
Bioorganic chemistry 2023 Nov;140:106792
Bioorganic chemistry 2023 Nov;140:106792
Involvement of iNOS-induced reactive enteric glia cells in gastrointestinal motility disorders of postoperative Ileus mice.
Sun A, Hu A, Lin J, Wang L, Xie C, Shi Y, Hong Q, Zhao G
Journal of chemical neuroanatomy 2023 Nov;133:102312
Journal of chemical neuroanatomy 2023 Nov;133:102312
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Xiao C, Sun Y, Fan J, Nguyen W, Chen S, Long Y, Chen W, Zhu A, Liu B
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages.
Shen X, Chen H, Zhang H, Luo L, Wen T, Liu L, Hu Q, Wang L
International immunopharmacology 2023 Nov;124(Pt B):110965
International immunopharmacology 2023 Nov;124(Pt B):110965
Melatonin exerts a protective effect in ameliorating nephrolithiasis via targeting AMPK/PINK1-Parkin mediated mitophagy and inhibiting ferroptosis in vivo and in vitro.
Zhou J, Meng L, He Z, Song Q, Liu J, Su X, Wang C, Ke H, Dong C, Liao W, Yang S
International immunopharmacology 2023 Nov;124(Pt A):110801
International immunopharmacology 2023 Nov;124(Pt A):110801
miR-214 could promote myocardial fibrosis and cardiac mesenchymal transition in VMC mice through regulation of the p53 or PTEN-PI3K-Akt signali pathway, promoting CF proliferation and inhibiting its ng pathway.
Huang X, Zheng D, Liu C, Huang J, Chen X, Zhong J, Wang J, Lin X, Zhao C, Chen M, Su S, Chen Y, Xu C, Lin C, Huang Y, Zhang S
International immunopharmacology 2023 Nov;124(Pt A):110765
International immunopharmacology 2023 Nov;124(Pt A):110765
The efficacy and mechanism of Angelica sinensis (Oliv.) Diels root aqueous extract based on RNA sequencing and 16S rDNA sequencing in alleviating polycystic ovary syndrome.
Gao Y, Mo S, Cao H, Zhi Y, Ma X, Huang Z, Li B, Wu J, Zhang K, Jin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155013
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155013
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma.
Song M, Ma L, Shen C, Liu W, Zhang P, Bi R, Zhao C
Cellular signalling 2023 Nov;111:110828
Cellular signalling 2023 Nov;111:110828
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
An B, Nie W, Hu J, Fan Y, Nie H, Wang M, Zhao Y, Yao H, Ren Y, Zhang C, Wei M, Li W, Liu J, Yang C, Zhang Y, Li X, Tian G
Cell death & disease 2023 Nov 9;14(11):728
Cell death & disease 2023 Nov 9;14(11):728
Chitobiose exhibited a lipid-lowering effect in ob/ob(-/-) mice via butyric acid enrolled liver-gut crosstalk.
Zhuang X, Zhao M, Ji X, Yang S, Yin H, Zhao L
Bioresources and bioprocessing 2023 Nov 9;10(1):79
Bioresources and bioprocessing 2023 Nov 9;10(1):79
WISP1 Is Involved in the Pathogenesis of Kashin-Beck Disease via the Autophagy Pathway.
Li P, Cheng B, Yao Y, Yu W, Liu L, Cheng S, Zhang L, Ma M, Qi X, Liang C, Chu X, Ye J, Sun S, Jia Y, Guo X, Wen Y, Zhang F
International journal of molecular sciences 2023 Nov 7;24(22)
International journal of molecular sciences 2023 Nov 7;24(22)
Role of steroid receptor-associated and regulated protein in tumor progression and progesterone receptor signaling in endometrial cancer.
Liu J, Wang Z, Zhou J, Wang J, He X, Wang J
Chinese medical journal 2023 Nov 5;136(21):2576-2586
Chinese medical journal 2023 Nov 5;136(21):2576-2586
Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function.
Wang Y, Sun Z, Ping J, Tang J, He B, Chang T, Zhou Q, Yuan S, Tang Z, Li X, Lu Y, He R, He X, Liu Z, Yin L, Wu N
Nature communications 2023 Nov 4;14(1):7075
Nature communications 2023 Nov 4;14(1):7075
DHA and EPA inhibit porcine coronavirus replication by alleviating ER stress.
Suo X, Wang J, Wang D, Fan G, Zhu M, Fan B, Yang X, Li B
Journal of virology 2023 Nov 30;97(11):e0120923
Journal of virology 2023 Nov 30;97(11):e0120923
Hypoxia and HIF-1α promote lytic de novo KSHV infection.
Lee S-C, Naik NG, Tombácz D, Gulyás G, Kakuk B, Boldogkői Z, Hall K, Papp B, Boulant S, Toth Z
Journal of virology 2023 Nov 30;97(11):e0097223
Journal of virology 2023 Nov 30;97(11):e0097223
Effective-compound combination of Bufei Yishen formula III combined with ER suppress airway mucus hypersecretion in COPD rats: via EGFR/MAPK signaling.
Xu K, Ma J, Lu R, Shao X, Zhao Y, Cui L, Qiu Z, Tian Y, Li J
Bioscience reports 2023 Nov 30;43(11)
Bioscience reports 2023 Nov 30;43(11)
Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer.
He L, Shi M, Ren S, Zhang J, Tian Y, Yang X, Liu H
Biomolecules & biomedicine 2023 Nov 3;23(6):1026-1037
Biomolecules & biomedicine 2023 Nov 3;23(6):1026-1037
Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.
Cui D, Wang Z, Dang Q, Wang J, Qin J, Song J, Zhai X, Zhou Y, Zhao L, Lu G, Liu H, Liu G, Liu R, Shao C, Zhang X, Liu Z
Nature communications 2023 Nov 3;14(1):7032
Nature communications 2023 Nov 3;14(1):7032
Inhibition of Ferroptosis Ameliorates Photoreceptor Degeneration in Experimental Diabetic Mice.
Gao S, Gao S, Wang Y, Li N, Yang Z, Yao H, Chen Y, Cheng Y, Zhong Y, Shen X
International journal of molecular sciences 2023 Nov 29;24(23)
International journal of molecular sciences 2023 Nov 29;24(23)
SHED-derived exosomes attenuate trigeminal neuralgia after CCI of the infraorbital nerve in mice via the miR-24-3p/IL-1R1/p-p38 MAPK pathway.
Guo R, Fang Y, Zhang Y, Liu L, Li N, Wu J, Yan M, Li Z, Yu J
Journal of nanobiotechnology 2023 Nov 29;21(1):458
Journal of nanobiotechnology 2023 Nov 29;21(1):458
Lysyl oxidase inhibits BMP9-induced osteoblastic differentiation through reducing Wnt/β-catenin via HIF-1a repression in 3T3-L1 cells.
Zhang J, Ye F, Ye A, He B
Journal of orthopaedic surgery and research 2023 Nov 29;18(1):911
Journal of orthopaedic surgery and research 2023 Nov 29;18(1):911
Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway.
Mai Z, Liu J, Jiang X, Gu W, Wang W, Li S, Schmalz G, Xiao H, Zhao J
Biology direct 2023 Nov 29;18(1):81
Biology direct 2023 Nov 29;18(1):81
Role of LncMALAT1-miR-141-3p/200a-3p-NRXN1 Axis in the Impairment of Learning and Memory Capacity in ADHD.
Mu Y, Li J, Zhang S, Zhong F, Zhang X, Song J, Yuan H, Tian T, Hu Y
Physiological research 2023 Nov 28;72(5):645-656
Physiological research 2023 Nov 28;72(5):645-656
Lactoferrin Alleviates Ethanol-Induced Injury via Promoting Nrf2 Nuclear Translocation in BRL-3A Rat Liver Cells.
Li D, Ding L, Yan Y, Xing Y, Xu J, Qin L
International journal of molecular sciences 2023 Nov 28;24(23)
International journal of molecular sciences 2023 Nov 28;24(23)
Micronano Titanium Accelerates Mesenchymal Stem Cells Aging through the Activation of Senescence-Associated Secretory Phenotype.
Li X, Luo X, He Y, Xu K, Ding Y, Gao P, Tao B, Li M, Tan M, Liu S, Liu P, Cai K
ACS nano 2023 Nov 28;17(22):22885-22900
ACS nano 2023 Nov 28;17(22):22885-22900
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
Vacondio D, Nogueira Pinto H, Coenen L, Mulder IA, Fontijn R, van Het Hof B, Fung WK, Jongejan A, Kooij G, Zelcer N, Rozemuller AJ, de Vries HE, de Wit NM
Cell death & disease 2023 Nov 28;14(11):781
Cell death & disease 2023 Nov 28;14(11):781
Scleral remodeling in early adulthood: the role of FGF-2.
Qin Y, Liu T, Zhang Z, Xing S, Gong L, Ni Y
Scientific reports 2023 Nov 27;13(1):20779
Scientific reports 2023 Nov 27;13(1):20779
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Xia Y, Zhang Y, Sun Y, He L
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival.
Ye M, Liu T, Liu S, Tang R, Liu H, Zhang F, Luo S, Li M
Cell death discovery 2023 Nov 25;9(1):425
Cell death discovery 2023 Nov 25;9(1):425
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
Zhu J, Xu F, Lai H, Yuan H, Li XY, Hu J, Li W, Liu L, Wang C
Communications biology 2023 Nov 25;6(1):1201
Communications biology 2023 Nov 25;6(1):1201
FARSB Facilitates Hepatocellular Carcinoma Progression by Activating the mTORC1 Signaling Pathway.
Wang Y, Wang G, Hu S, Yin C, Zhao P, Zhou X, Shao S, Liu R, Hu W, Liu GL, Ke W, Song Z
International journal of molecular sciences 2023 Nov 24;24(23)
International journal of molecular sciences 2023 Nov 24;24(23)
Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation.
Sun S, Zheng Z, Wang J, Li F, He A, Lai K, Zhang S, Lu JH, Tian R, Tan CSH
Nature communications 2023 Nov 24;14(1):7697
Nature communications 2023 Nov 24;14(1):7697
Cell-based screen identifies porphyrins as FGFR3 activity inhibitors with therapeutic potential for achondroplasia and cancer.
Lin YW, Kao HJ, Chen WT, Kao CF, Wu JY, Chen YT, Lee YC
JCI insight 2023 Nov 22;8(22)
JCI insight 2023 Nov 22;8(22)
The role of miRNA-144-3p/Oprk1/KOR in nicotine dependence and nicotine withdrawal in male rats.
Shao J, Fei Y, Xiao J, Wang L, Zou S, Yang J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2023 Nov 22;25(12):1856-1864
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2023 Nov 22;25(12):1856-1864
The cellular trajectories of tumor-associated macrophages decipher the heterogeneity of pancreatic cancer.
Lin J, Lu F, Wu Y, Huang H, Pan Y
Functional & integrative genomics 2023 Nov 22;23(4):343
Functional & integrative genomics 2023 Nov 22;23(4):343
A prognostic risk model for programmed cell death and revealing TRIB3 as a promising apoptosis suppressor in renal cell carcinoma.
Fu Q, Yi B, Su Q, Huang Y, Wang L, Zhang Z
Aging 2023 Nov 22;15(22):13213-13238
Aging 2023 Nov 22;15(22):13213-13238
Chlorogenic Acid Alleviated AFB1-Induced Hepatotoxicity by Regulating Mitochondrial Function, Activating Nrf2/HO-1, and Inhibiting Noncanonical NF-κB Signaling Pathway.
Wang Q, Liu T, Koci M, Wang Y, Fu Y, Ma M, Ma Q, Zhao L
Antioxidants (Basel, Switzerland) 2023 Nov 22;12(12)
Antioxidants (Basel, Switzerland) 2023 Nov 22;12(12)
High-intensity interval training alleviates exhaustive exercise-induced HSP70-assisted selective autophagy in skeletal muscle.
Lu J, Zhang LM, Liu JJ, Liu YT, Lin XY, Wang XQ, Zhang Y, Tang Q, Liu L
The journal of physiological sciences : JPS 2023 Nov 21;73(1):32
The journal of physiological sciences : JPS 2023 Nov 21;73(1):32
Immunological characteristics of immunogenic cell death genes and malignant progression driving roles of TLR4 in anaplastic thyroid carcinoma.
Xu T, Zhu C, Song F, Zhang W, Yuan M, Pan Z, Huang P
BMC cancer 2023 Nov 21;23(1):1131
BMC cancer 2023 Nov 21;23(1):1131
m6A methyltransferase METTL3 contributes to sympathetic hyperactivity post-MI via promoting TRAF6-dependent mitochondrial ROS production.
Yang P, Wang Y, Ge W, Jing Y, Hu H, Yin J, Xue M, Wang Y, Li X, Li X, Shi Y, Tan J, Li Y, Yan S
Free radical biology & medicine 2023 Nov 20;209(Pt 2):342-354
Free radical biology & medicine 2023 Nov 20;209(Pt 2):342-354
SERPINE1 and SERPINB7 as potential biomarkers for intravenous vitamin C treatment in non-small-cell lung cancer.
Ou J, Liao Q, Du Y, Xi W, Meng Q, Li K, Cai Q, Pang CLK
Free radical biology & medicine 2023 Nov 20;209(Pt 1):96-107
Free radical biology & medicine 2023 Nov 20;209(Pt 1):96-107
Exosomes derived from cardiac fibroblasts with angiotensin II stimulation provoke hypertrophy and autophagy inhibition in cardiomyocytes.
Xu ST, Zhang YX, Liu SL, Liu F, Ye JT
Biochemical and biophysical research communications 2023 Nov 19;682:199-206
Biochemical and biophysical research communications 2023 Nov 19;682:199-206
Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway.
Cai T, Chen S, Wu C, Lou C, Wang W, Lin C, Jiang H, Xu X
BMC musculoskeletal disorders 2023 Nov 17;24(1):894
BMC musculoskeletal disorders 2023 Nov 17;24(1):894
MiR-184 targeting FOXO1 regulates host-cell oxidative stress induced by Chlamydia psittaci via the Wnt/β-catenin signaling pathway.
Chen L, Huang Q, Luo Y, Zhou Y, Tong T, Chen Y, Bai Q, Lu C, Li Z
Infection and immunity 2023 Nov 16;91(11):e0033723
Infection and immunity 2023 Nov 16;91(11):e0033723
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions.
Ji H, Lu X, Zhao S, Wang Q, Liao B, Bauer LG, Huber KVM, Luo R, Tian R, Tan CSH
Cell chemical biology 2023 Nov 16;30(11):1478-1487.e7
Cell chemical biology 2023 Nov 16;30(11):1478-1487.e7
USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase separation potential.
Wang Y, Mao A, Liu J, Li P, Zheng S, Tong T, Li Z, Zhang H, Ma L, Lin J, Pang Z, Han Q, Qi F, Zhang X, Chen M, He X, Zhang X, Fei T, Liu BF, Gao D, Cao L, Wang Q, Li Y, Sheng R
Cell chemical biology 2023 Nov 16;30(11):1436-1452.e10
Cell chemical biology 2023 Nov 16;30(11):1436-1452.e10
Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy.
Luo F, Yang G, Bai X, Yuan D, Li L, Wang D, Lu X, Cheng Y, Wang Y, Song X, Zhao Y
Cell chemical biology 2023 Nov 16;30(11):1390-1401.e6
Cell chemical biology 2023 Nov 16;30(11):1390-1401.e6
COL10A1 promotes tumorigenesis by modulating CD276 in pancreatic adenocarcinoma.
Xu Q, Zheng J, Su Z, Chen B, Gu S
BMC gastroenterology 2023 Nov 16;23(1):397
BMC gastroenterology 2023 Nov 16;23(1):397
Inhibition of Galectin-1 attenuates lung fibroblast activation and proliferation in lung fibrosis.
Xue J, Li S
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 15;69(11):213-218
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 15;69(11):213-218
Dimethyl fumarate attenuates cholestatic liver injury by activating the NRF2 and FXR pathways and suppressing NLRP3/GSDMD signaling in mice.
Xu Z, Tang W, Xie Q, Cao X, Zhang M, Zhang X, Chai J
Experimental cell research 2023 Nov 15;432(2):113781
Experimental cell research 2023 Nov 15;432(2):113781
Activation of the Nrf-2 pathway by pinocembrin safeguards vertebral endplate chondrocytes against apoptosis and degeneration caused by oxidative stress.
Wang H, Liu X, Yang H, Jing X, Wang W, Liu X, Zhang B, Liu X, Shao Y, Cui X
Life sciences 2023 Nov 15;333:122162
Life sciences 2023 Nov 15;333:122162
Exploring the effect and mechanism of Haizao Yuhu decoction containing three variants of glycyrrhiza on goiter using an integrated strategy of network pharmacology and RNA sequencing.
Li M, Xiu L, Liao W, Ren Y, Huo M, Liu H, Chen S, Li N, Gao Y, Yu X, Fan A, Zhong G
Journal of ethnopharmacology 2023 Nov 15;316:116750
Journal of ethnopharmacology 2023 Nov 15;316:116750
Network pharmacology-based approach uncovers the pharmacodynamic components and mechanism of Fructus Tribuli for improving endothelial dysfunction in hypertension.
Wang SY, Sun XC, Lv XY, Li JN, Han B, Liu KL, Wang S, Sheng HG, Zhang C, Guo F, Cui YD
Journal of ethnopharmacology 2023 Nov 15;316:116749
Journal of ethnopharmacology 2023 Nov 15;316:116749
Potential 'anti-cancer' effects of esketamine on proliferation, apoptosis, migration and invasion in esophageal squamous carcinoma cells.
Li C, Shi J, Wei S, Jia H
European journal of medical research 2023 Nov 15;28(1):517
European journal of medical research 2023 Nov 15;28(1):517
RhoA suppresses pseudorabies virus replication in vitro.
Li XM, Wang SP, Wang JY, Tang T, Wan B, Zeng L, Wang J, Chu BB, Yang GY, Pan JJ
Virology journal 2023 Nov 15;20(1):264
Virology journal 2023 Nov 15;20(1):264
Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth.
He K, Xie CZ, Li Y, Chen ZZ, Xu SH, Huang SQ, Yang JG, Wei ZQ, Peng XD
World journal of gastrointestinal oncology 2023 Nov 15;15(11):1936-1950
World journal of gastrointestinal oncology 2023 Nov 15;15(11):1936-1950
Grid2 interacting protein is a potential biomarker related to immune infiltration in colorectal cancer.
Zhao J, Quan J, Chen W, Xie X
European journal of medical research 2023 Nov 14;28(1):511
European journal of medical research 2023 Nov 14;28(1):511
Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins.
Dai S, Min YQ, Li Q, Feng K, Jiang Z, Wang Z, Zhang C, Ren F, Fang Y, Zhang J, Zhu Q, Wang M, Wang H, Deng F, Ning YJ
Nature communications 2023 Nov 14;14(1):7365
Nature communications 2023 Nov 14;14(1):7365
NeuroD1 administration ameliorated neuroinflammation and boosted neurogenesis in a mouse model of subarachnoid hemorrhage.
Chen P, Liu XY, Lin MH, Li YX, Kang DZ, Ye ZC, Lin QS
Journal of neuroinflammation 2023 Nov 12;20(1):261
Journal of neuroinflammation 2023 Nov 12;20(1):261
In situ visualization of m6A sites in cellular mRNAs.
Sheehan CJ, Marayati BF, Bhatia J, Meyer KD
Nucleic acids research 2023 Nov 10;51(20):e101
Nucleic acids research 2023 Nov 10;51(20):e101
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Wu M, Chen C, Lei H, Cao Z, Zhang C, Du R, Zhang C, Song Y, Qin M, Zhou J, Lu Y, Wang X, Zhang L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Low-intensity ultrasound combined with arsenic trioxide induced apoptosis of glioma via EGFR/AKT/mTOR.
Fang Y, Bai Z, Cao J, Zhang G, Li X, Li S, Yan Y, Gao P, Kong X, Zhang Z
Life sciences 2023 Nov 1;332:122103
Life sciences 2023 Nov 1;332:122103
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Zhang Y, Liang J, Gu H, Du T, Xu P, Yu T, He Q, Huang Z, Lei S, Li J
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
Carbamazepine regulates USP10 through miR-20a-5p to affect the deubiquitination of SKP2 and inhibit osteogenic differentiation.
Wang H, Liu Z, Niu D, Li H, Han Y, Peng J, Qian Q
Journal of orthopaedic surgery and research 2023 Nov 1;18(1):820
Journal of orthopaedic surgery and research 2023 Nov 1;18(1):820
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Miao Y, Zhang S, Liang Z, Wang Y, Tian D, Jin S, Guo Q, Xue H, Teng X, Xiao L, Wu Y
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Sevoflurane Preconditioning Alleviates Posttraumatic Stress Disorder-Induced Apoptosis in the Hippocampus via the EZH2-Regulated Akt/mTOR Axis and Improves Synaptic Plasticity.
Gu T, Xu C, Meng X, Gao D, Jiang G, Yin A, Liu Q, Zhang L
Journal of molecular neuroscience : MN 2023 May;73(4-5):225-236
Journal of molecular neuroscience : MN 2023 May;73(4-5):225-236
Enhanced Hypoglycemic Bioactivity via RAS/Raf-1/MEK/ERK Signaling Pathway by Combining Capsaicin and QUERCETIN from Chili Peppers.
Mi S, Zhu W, Zhang X, Wang Y, Li T, Wang X
Molecular nutrition & food research 2023 May;67(10):e2200577
Molecular nutrition & food research 2023 May;67(10):e2200577
Inhibition of endogenous hydrogen sulfide production suppresses the growth of nasopharyngeal carcinoma cells.
Wang DY, Zhang J, Li HX, Zhang YX, Jing MR, Cai CB, Wang D, Qi HW, Wang YZ, Chen HJ, Li T, Zhai YK, Ji XY, Wu DD
Molecular carcinogenesis 2023 May;62(5):652-664
Molecular carcinogenesis 2023 May;62(5):652-664
A novel lncRNA 495810 promotes the aerobic glycolysis in colorectal cancer by stabilizing pyruvate kinase isozyme M2.
Cui K, Wu H, Zhang L, Li H, Israr G, Li Z
International journal of oncology 2023 May;62(5)
International journal of oncology 2023 May;62(5)
BML-111 inhibits osteoclast differentiation by suppressing the MAPK and NF-κB pathways, alleviating deterioration of the knee joints in a CIA rat model.
Wang L, Su W, Zheng X, Lin W, Lv C, Yang S, Chen B, Zhang C
Cell biology international 2023 May;47(5):954-968
Cell biology international 2023 May;47(5):954-968
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Xi Y, Chi Z, Tao X, Zhai X, Zhao Z, Ren J, Yang S, Dong D
Environmental toxicology 2023 May;38(5):1153-1161
Environmental toxicology 2023 May;38(5):1153-1161
Comparative study of cigarette smoke, Klebsiella pneumoniae, and their combination on airway epithelial barrier function in mice.
Li K, Mei X, Xu K, Jia L, Zhao P, Tian Y, Li J
Environmental toxicology 2023 May;38(5):1133-1142
Environmental toxicology 2023 May;38(5):1133-1142
A novel mechanism of cannabidiol in suppressing ovarian cancer through LAIR-1 mediated mitochondrial dysfunction and apoptosis.
Ma L, Zhang H, Liu C, Liu M, Shangguan F, Liu Y, Yang S, Li H, An J, Song S, Cao Q, Qu G
Environmental toxicology 2023 May;38(5):1118-1132
Environmental toxicology 2023 May;38(5):1118-1132
Decreased DANCR contributes to high glucose-induced extracellular matrix accumulation in human renal mesangial cell via regulating the TGF-β/Smad signaling.
Liu F, Cao Y, Zhang C, Su H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22926
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22926
Mesenchymal stem cell exosomes as nanotherapeutics for dry age-related macular degeneration.
Tang Y, Kang Y, Zhang X, Cheng C
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:356-370
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:356-370
EIF4A3-induced circular RNA SCAP facilitates tumorigenesis and progression of non-small-cell lung cancer via miR-7/SMAD2 signaling.
Zhang Y, Qi W, Wu Y
Environmental science and pollution research international 2023 May;30(24):65237-65249
Environmental science and pollution research international 2023 May;30(24):65237-65249
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Lu Y, Liu M, Guo X, Wang P, Zeng F, Wang H, Tang J, Qin Z, Tao T
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Li L, Cao X, Huang L, Huang X, Gu J, Yu X, Zhu Y, Zhou Y, Song Y, Zhu M
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Methionine alleviates heat stress-induced ferroptosis in bovine mammary epithelial cells through the Nrf2 pathway.
Xu J, Wang XL, Zeng HF, Han ZY
Ecotoxicology and environmental safety 2023 May;256:114889
Ecotoxicology and environmental safety 2023 May;256:114889
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
Wang R, Gao D, Chen C, Fan G, Cheng H, Tao Y, Lu J, Tian J, Wang Y, Wang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 May;25(5):1425-1435
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 May;25(5):1425-1435
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Rong Y, Wang Z, Tang P, Wang J, Ji C, Chang J, Zhu Y, Ye W, Bai J, Liu W, Yin G, Yu L, Zhou X, Cai W
Bioactive materials 2023 May;23:328-342
Bioactive materials 2023 May;23:328-342
Pioglitazone can improve liver sex hormone-binding globulin levels and lipid metabolism in polycystic ovary syndrome by regulating hepatocyte nuclear factor-4α.
Zhao H, Wang D, Xing C, Lv B, Wang X, He B
The Journal of steroid biochemistry and molecular biology 2023 May;229:106265
The Journal of steroid biochemistry and molecular biology 2023 May;229:106265
Periplocin targets low density lipoprotein receptor-related protein 4 to attenuate osteoclastogenesis and protect against osteoporosis.
Zhang X, Sun Z, Zhang Y, Pan L, Jiang W, Dong H, Jin Z, Kang J, Liu R, Ning B
Biochemical pharmacology 2023 May;211:115516
Biochemical pharmacology 2023 May;211:115516
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Xu H, Wang Z, Yang H, Zhu J, Hu Z
International wound journal 2023 May;20(5):1700-1711
International wound journal 2023 May;20(5):1700-1711
Berberine attenuates sunitinib-induced cardiac dysfunction by normalizing calcium regulation disorder via SGK1 activation.
Li C, Wu W, Xing J, Yan W, Zhang J, Sun J, Zhang Z, Qiu S, Xu Y, Wang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113743
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113743
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
Chen H, Tao X, Cao H, Li B, Sun Q, Wang W, Zou Y, Mu M, Tao H, Zhao Y, Ge D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Xia G, Wen Z, Zhang L, Huang J, Wang X, Liang C, Cui X, Cao X, Wu S
Experimental gerontology 2023 May;175:112140
Experimental gerontology 2023 May;175:112140
Prophylactic effect of Tongxieyaofang polysaccharide on depressive behavior in adolescent male mice with chronic unpredictable stress through the microbiome-gut-brain axis.
Chen H, Kan Q, Zhao L, Ye G, He X, Tang H, Shi F, Zou Y, Liang X, Song X, Liu R, Luo J, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114525
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114525
Identification of MAP Kinase Kinase 3 as a protein target of myricetin in non-small cell lung cancer cells.
Gu L, Li Z, Zhang X, Chen M, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114460
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114460
Epigallocatechin-3-gallate (EGCG) based metal-polyphenol nanoformulations alleviates chondrocytes inflammation by modulating synovial macrophages polarization.
Wei H, Qin J, Huang Q, Jin Z, Zheng L, Zhao J, Qin Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114366
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114366
SMURF1 inhibits the Th17 and Th17.1 polarization and improves the Treg/Th17 imbalance in systemic lupus erythematosus through the ubiquitination of RORγt.
Zhong W, Feng L, Tian W, Qu H, Xu H, Ning K, Liu L, Liu W, Gong X, Chen H
Molecular immunology 2023 May;157:186-194
Molecular immunology 2023 May;157:186-194
Design, synthesis and bioevaluation of 1,2,4-thiadiazolidine-3,5-dione derivatives as potential GSK-3β inhibitors for the treatment of Alzheimer's disease.
Dong Y, Lu J, Zhang S, Chen L, Wen J, Wang F, Mao Y, Li L, Zhang J, Liao S, Dong L
Bioorganic chemistry 2023 May;134:106446
Bioorganic chemistry 2023 May;134:106446
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A-YTHDF2-dependent manner.
Shen D, Lin J, Xie Y, Zhuang Z, Xu G, Peng S, Tang G, Bai L, Zhu M, Zhang Y, Huang Z, Wang P, Liu X, Huang M, Luo Y, Wang X, Yu H
Clinical and translational medicine 2023 May;13(5):e1279
Clinical and translational medicine 2023 May;13(5):e1279
Sulfotransferase 1C2 promotes hepatocellular carcinoma progression by enhancing glycolysis and fatty acid metabolism.
Jiang L, Xu F, Li C, Liu T, Zhao Q, Liu Y, Zhao Y, Li Y, Zhang Z, Tang X, Zhang J
Cancer medicine 2023 May;12(9):10738-10754
Cancer medicine 2023 May;12(9):10738-10754
Intrafibrillar Mineralization and Immunomodulatory for Synergetic Enhancement of Bone Regeneration via Calcium Phosphate Nanocluster Scaffold.
Zhou Y, Hu Z, Jin W, Wu H, Zuo M, Shao C, Lan Y, Shi Y, Tang R, Chen Z, Xie Z, Shi J
Advanced healthcare materials 2023 May;12(12):e2201548
Advanced healthcare materials 2023 May;12(12):e2201548
Eriocitrin attenuates sepsis-induced acute lung injury in mice by regulating MKP1/MAPK pathway mediated-glycolysis.
Li D, Yang L, Wang W, Song C, Xiong R, Pan S, Li N, Geng Q
International immunopharmacology 2023 May;118:110021
International immunopharmacology 2023 May;118:110021
MiR-223-3p regulates the eosinophil degranulation and enhances the inflammation in allergic rhinitis by targeting FBXW7.
Wu S, Wang Z, Zhu Y, Zhu X, Guo L, Fu Y, Zhang Q, Mou X, Liu Y
International immunopharmacology 2023 May;118:110007
International immunopharmacology 2023 May;118:110007
Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation.
Zhang X, Huang S, Zhuang Z, Han X, Xie M, Yu S, Hua M, Liang Z, Meng C, Yin L, Zhuang X, Chen S
International immunopharmacology 2023 May;118:109930
International immunopharmacology 2023 May;118:109930
XinLi formula, a traditional Chinese decoction, alleviates chronic heart failure via regulating the interaction of AGTR1 and AQP1.
Wei XH, Liu WJ, Jiang W, Lan TH, Pan H, Ma MY, You LZ, Shang HC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154722
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154722
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
Zhang C, Wei S, Dai S, Li X, Wang H, Zhang H, Sun G, Shan B, Zhao L
Journal for immunotherapy of cancer 2023 May;11(5)
Journal for immunotherapy of cancer 2023 May;11(5)
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
Du C, Cheng Q, Zhao P, Wang C, Zhu Z, Wu X, Gao S, Chen B, Zou J, Huang W, Liao J
Genes & diseases 2023 May;10(3):1040-1054
Genes & diseases 2023 May;10(3):1040-1054
Spatiotemporal Characterization of Human Early Intervertebral Disc Formation at Single-Cell Resolution.
Zhou T, Chen Y, Liao Z, Zhang L, Su D, Li Z, Yang X, Ke X, Liu H, Chen Y, Weng R, Shen H, Xu C, Wan Y, Xu R, Su P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2206296
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2206296
Overexpression of Podoplanin Predicts Poor Prognosis in Patients With Glioma.
He J, Zhang G, Yuan Q, Wang S, Liu Z, Wang M, Cai H, Wan J, Zhao B
Applied immunohistochemistry & molecular morphology : AIMM 2023 May-Jun 01;31(5):295-303
Applied immunohistochemistry & molecular morphology : AIMM 2023 May-Jun 01;31(5):295-303
Structure-guided identification of novel dual-targeting estrogen receptor α degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer.
Xin L, Min J, Hu H, Li Y, Du C, Xie B, Cheng Y, Deng X, Deng X, Shen K, Huang J, Chen CC, Guo RT, Dong C, Zhou HB
European journal of medicinal chemistry 2023 May 5;253:115328
European journal of medicinal chemistry 2023 May 5;253:115328
Natural Compounds, Optimal Combination of Brusatol and Polydatin Promote Anti-Tumor Effect in Breast Cancer by Targeting Nrf2 Signaling Pathway.
Li J, Zhang J, Zhu Y, Afolabi LO, Chen L, Feng X
International journal of molecular sciences 2023 May 5;24(9)
International journal of molecular sciences 2023 May 5;24(9)
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Bu J, Zhang Y, Wu S, Li H, Sun L, Liu Y, Zhu X, Qiao X, Ma Q, Liu C, Niu N, Xue J, Chen G, Yang Y, Liu C
Nature communications 2023 May 5;14(1):2602
Nature communications 2023 May 5;14(1):2602
The Host Protein CAD Regulates the Replication of FMDV through the Function of Pyrimidines' De Novo Synthesis.
Yang P, Yuan Y, Sun Y, Lv B, Du H, Zhou Z, Yang Z, Liu X, Duan H, Shen C
Journal of virology 2023 May 31;97(5):e0036923
Journal of virology 2023 May 31;97(5):e0036923
Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43.
Huang SN, Pan YT, Zhou YP, Wang XZ, Mei MJ, Yang B, Li D, Zeng WB, Cheng S, Sun JY, Cheng H, Zhao F, Luo MH
Journal of virology 2023 May 31;97(5):e0031323
Journal of virology 2023 May 31;97(5):e0031323
Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1.
Yang R, Li L, Hou Y, Li Y, Zhang J, Yang N, Zhang Y, Ji W, Yu T, Lv L, Liang H, Li X, Li T, Shan H
Cell death & disease 2023 May 30;14(5):344
Cell death & disease 2023 May 30;14(5):344
Transcriptional coactivation by EHMT2 restricts glucocorticoid-induced insulin resistance in a study with male mice.
Lee RA, Chang M, Yiv N, Tsay A, Tian S, Li D, Poulard C, Stallcup MR, Pufall MA, Wang JC
Nature communications 2023 May 30;14(1):3143
Nature communications 2023 May 30;14(1):3143
A Potential Adhesin/Invasin STM0306 Participates in Host Cell Inflammation Induced by Salmonella enterica Serovar Typhimurium.
Ling C, Liang S, Li Y, Cao Q, Ye H, Zhang C, Dong Z, Feng D, Wang W, Zuo J
International journal of molecular sciences 2023 May 3;24(9)
International journal of molecular sciences 2023 May 3;24(9)
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
Wu M, Song D, Li H, Ahmad N, Xu H, Yang X, Wang Q, Cheng X, Deng S, Shu X
International journal of molecular sciences 2023 May 29;24(11)
International journal of molecular sciences 2023 May 29;24(11)
Integrated pan-cancer analysis of centromere protein F and experimental verification of its role and clinical significance in cholangiocarcinoma.
Cao Z, Zeng L, Wang Z, Wen X, Zhang J
Functional & integrative genomics 2023 May 29;23(2):190
Functional & integrative genomics 2023 May 29;23(2):190
Pyroptosis of Macrophages Induced by Clostridium perfringens Beta-1 Toxin.
Zhang S, Ma L, Song F, Wang D, Shi K, Li Y, Zeng J, Wang Y
Toxins 2023 May 29;15(6)
Toxins 2023 May 29;15(6)
Impairment of rigidity sensing caused by mutant TP53 gain of function in osteosarcoma.
Luo M, Huang M, Yang N, Zhu Y, Huang P, Xu Z, Wang W, Cai L
Bone research 2023 May 29;11(1):28
Bone research 2023 May 29;11(1):28
Development and validation of a novel T cell proliferation-related prognostic model for predicting survival and immunotherapy benefits in melanoma.
Chen J, Wang D, Chan S, Yang Q, Wang C, Wang X, Sun R, Gui Y, Yu S, Yang J, Zhang H, Zhang X, Tang K, Zhang H, Liu S
Aging 2023 May 24;15(10):4444-4464
Aging 2023 May 24;15(10):4444-4464
BESST: a novel LncRNA knockout strategy with less genome perturbance.
Zhang S, Chen Y, Dong K, Zhao Y, Wang Y, Wang S, Qu C, Xu N, Xie W, Zeng C, Lyu QR, Zhang Y
Nucleic acids research 2023 May 22;51(9):e49
Nucleic acids research 2023 May 22;51(9):e49
Hairy gene homolog increases nasopharyngeal carcinoma cell stemness by upregulating Bmi-1.
Lei Y, Shen HF, Li QW, Yang S, Xie HT, Li XF, Chen ML, Xia JW, Wang SC, Dai GQ, Zhou Y, Li YC, Huang SH, He DH, Zhou ZH, Cong JG, Lin XL, Lin TY, Wu AB, Xiao D, Xiao SJ, Zhang XK, Jia JS
Aging 2023 May 22;15(10):4391-4410
Aging 2023 May 22;15(10):4391-4410
Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis.
Fan P, Meng H, Hao W, Zheng Y, Li H, Zhang Z, Du L, Guo X, Wang D, Wang Y, Wu H
Food & function 2023 May 22;14(10):4905-4920
Food & function 2023 May 22;14(10):4905-4920
CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer.
Zhang X, Zheng X, Ying X, Xie W, Yin Y, Wang X
Journal of translational medicine 2023 May 20;21(1):334
Journal of translational medicine 2023 May 20;21(1):334
An ankylosing spondylitis risk variant alters osteoclast differentiation.
Wu F, Han X, Liu J, Zhang Z, Yan K, Wang B, Yang L, Zou H, Yang C, Huang W, Jin L, Wang J, Qian F, Niu Z
Rheumatology (Oxford, England) 2023 May 2;62(5):1980-1987
Rheumatology (Oxford, England) 2023 May 2;62(5):1980-1987
Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
Hill SE, Beaulieu-Abdelahad D, Lemus A, Webster JM, Ospina SR, Darling AL, Martin MD, Patel S, Bridenstine L, Swonger R, Paul S, Blackburn R, Calcul L, Dickey CA, Leahy JW, Blair LJ
ACS chemical biology 2023 May 19;18(5):1124-1135
ACS chemical biology 2023 May 19;18(5):1124-1135
Mitochondrial impairment and downregulation of Drp1 phosphorylation underlie the antiproliferative and proapoptotic effects of alantolactone on oral squamous cell carcinoma cells.
Zhang Y, Yang B, Tu C, Ping Y, Chen S, Wu T, Zhao Z, Mao Y, Yang Z, Cao Z, Li J, Huang K, Ding X, Wu G, Zou P, Deng Z, Sun X
Journal of translational medicine 2023 May 18;21(1):328
Journal of translational medicine 2023 May 18;21(1):328
Regulatory Effects of FGF9 on Dermal Papilla Cell Proliferation in Small-Tailed Han Sheep.
Jia Q, Zhang S, Wang D, Liu J, Luo X, Liu Y, Li X, Sun F, Xia G, Zhang L
Genes 2023 May 18;14(5)
Genes 2023 May 18;14(5)
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Zhang ZH, Zhou XM, Zhang X
Brain sciences 2023 May 18;13(5)
Brain sciences 2023 May 18;13(5)
A New Method for Programmable RNA Editing Using CRISPR Effector Cas13X.1.
Li L, Liu W, Zhang H, Cai Q, Wen D, Du J, Sun J, Li L, Gao C, Lin P, Wu M, Jiang J
The Tohoku journal of experimental medicine 2023 May 17;260(1):51-61
The Tohoku journal of experimental medicine 2023 May 17;260(1):51-61
Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines.
Kanna M, Nakatsu Y, Yamamotoya T, Kushiyama A, Fujishiro M, Sakoda H, Ono H, Arihiro K, Asano T
International journal of molecular sciences 2023 May 16;24(10)
International journal of molecular sciences 2023 May 16;24(10)
Esketamine ameliorates post-stroke anxiety by modulating microglial HDAC3/NF-κB/COX1 inflammatory signaling in ischemic cortex.
Huang A, Chen Y, Wang S, Du H, Guan A, Wu H, Zhai Q, Duan N, Li X, Zhao P, Zhu Y, Bai J, Xiao Y, Yang T, Wang Q, Deng B
European journal of pharmacology 2023 May 15;947:175667
European journal of pharmacology 2023 May 15;947:175667
Osthole relieves skin damage and inhibits chronic itch through modulation of Akt/ZO-3 pathway in atopic dermatitis.
Hu X, Zhou Y, Shi J, Qi M, Li X, Yang Y, Zhu C, Wang C, Tang Z, Ma Y, Yu G
European journal of pharmacology 2023 May 15;947:175649
European journal of pharmacology 2023 May 15;947:175649
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury.
Sun X, Huang N, Li P, Dong X, Yang J, Zhang X, Zong WX, Gao S, Xin H
Life sciences 2023 May 15;321:121608
Life sciences 2023 May 15;321:121608
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway.
Liu Q, Xu L, Ren G, Zhao J, Shao Y, Lu T
Life sciences 2023 May 15;321:121591
Life sciences 2023 May 15;321:121591
Persistent Degradation of HER2 Protein by Hybrid nanoPROTAC for Programmed Cell Death.
Wang Z, Tan M, Su W, Huang W, Zhang J, Jia F, Cao G, Liu X, Song H, Ran H, Nie G, Wang H
Journal of medicinal chemistry 2023 May 11;66(9):6263-6273
Journal of medicinal chemistry 2023 May 11;66(9):6263-6273
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Zhang Q, Yang X, Liu J, Song J, Zhang S, Chen L, Zhang M
Food & function 2023 May 11;14(9):4191-4203
Food & function 2023 May 11;14(9):4191-4203
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Meng Z, Gao M, Wang C, Guan S, Zhang D, Lu J
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Zeng Y, Wu R, Wang F, Li S, Li L, Li Y, Qin P, Wei M, Yang J, Wu J, Chen A, Ke G, Yan Z, Yang H, Chen Z, Wang Z, Xiao W, Jiang Y, Chen X, Zeng Z, Zhao X, Chen P, Gong S
Cell host & microbe 2023 May 10;31(5):766-780.e7
Cell host & microbe 2023 May 10;31(5):766-780.e7
Integrative multi-omics and drug-response characterization of patient-derived prostate cancer primary cells.
Wang Z, Li Y, Zhao W, Jiang S, Huang Y, Hou J, Zhang X, Zhai Z, Yang C, Wang J, Zhu J, Pan J, Jiang W, Li Z, Ye M, Tan M, Jiang H, Dang Y
Signal transduction and targeted therapy 2023 May 1;8(1):175
Signal transduction and targeted therapy 2023 May 1;8(1):175
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Yang J, Li G, Huang Y, Liu Y
Toxicology and applied pharmacology 2023 May 1;466:116458
Toxicology and applied pharmacology 2023 May 1;466:116458
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Xi T, Wang R, Pi D, Ouyang J, Yang J
Experimental cell research 2023 May 1;426(1):113556
Experimental cell research 2023 May 1;426(1):113556
Interferon regulatory factor 4 deletion protects against kidney inflammation and fibrosis in deoxycorticosterone acetate/salt hypertension.
Gao Y, Liu B, Guo X, Nie J, Zou H, Wen S, Yu W, Liang H
Journal of hypertension 2023 May 1;41(5):794-810
Journal of hypertension 2023 May 1;41(5):794-810
The circadian rhythm gene Bmal1 ameliorates acute deoxynivalenol-induced liver damage.
Yang LN, Xu S, Tang M, Zhou X, Liao Y, Nüssler AK, Liu L, Yang W
Archives of toxicology 2023 Mar;97(3):787-804
Archives of toxicology 2023 Mar;97(3):787-804
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins.
Zhang S, Ming SL, Zeng L, Wang LF, Zhang C, Zhu HS, Yang GY, Zhang GP, Chu BB, Wang J
Journal of medical virology 2023 Mar;95(3):e28591
Journal of medical virology 2023 Mar;95(3):e28591
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Wang Y, Yang X, Cao Y, Li X, Xu R, Yan J, Guo Z, Sun S, Sun X, Wu Y
Heliyon 2023 Mar;9(3):e14475
Heliyon 2023 Mar;9(3):e14475
Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome.
Fan HX, Sheng S, Li DD, Li JJ, Wang GQ, Zhang F
Bioengineering & translational medicine 2023 Mar;8(2):e10455
Bioengineering & translational medicine 2023 Mar;8(2):e10455
Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1.
Wang QD, Liu LL, Li D, Gao L, Zhang MJ
Pathology international 2023 Mar;73(3):109-119
Pathology international 2023 Mar;73(3):109-119
Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt-GSK-3β-Nrf2 pathway.
Liu X, Liu Y, Chen L, Zhang Z, Cui L, Wei T
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Mar;72(3):373-385
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Mar;72(3):373-385
Oral administration of Lactobacillus plantarum JC7 alleviates OVA-induced murine food allergy through immunoregulation and restoring disordered intestinal microbiota.
Duan C, Ma L, Yu J, Sun Y, Liu L, Ma F, Li X, Li D
European journal of nutrition 2023 Mar;62(2):685-698
European journal of nutrition 2023 Mar;62(2):685-698
Regulation of telomere silencing by the core histones-autophagy-Sir2 axis.
Mei Q, Yu Q, Li X, Chen J, Yu X
Life science alliance 2023 Mar;6(3)
Life science alliance 2023 Mar;6(3)
Regulation of BCRP expression and sulfasalazine pharmacokinetics by the nuclear receptor REV-ERBα.
Wu C, Xiao Y, Wu C, Xie D, Luo M, Yao D, Chen M, Lu D
Xenobiotica; the fate of foreign compounds in biological systems 2023 Mar;53(3):215-222
Xenobiotica; the fate of foreign compounds in biological systems 2023 Mar;53(3):215-222
The effect of occlusal disharmony on a chronic stress-induced animal model of gut microbiota dysbiosis.
Wu L, Zhang S, Zhang M, Wang X, Li S, Rausch-Fan X, Chen J
Journal of oral rehabilitation 2023 Mar;50(3):223-233
Journal of oral rehabilitation 2023 Mar;50(3):223-233
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis.
Wu YY, Xiao YF, Tian LX, He B, Liu J, Li ZB, Yang H, Chen Y, Luo Q, Li BS, Yang SM
Oncogene 2023 Mar;42(14):1144-1156
Oncogene 2023 Mar;42(14):1144-1156
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing.
Yu XM, Li SJ, Yao ZT, Xu JJ, Zheng CC, Liu ZC, Ding PB, Jiang ZL, Wei X, Zhao LP, Shi XY, Li ZG, Xu WW, Li B
Oncogene 2023 Mar;42(14):1101-1116
Oncogene 2023 Mar;42(14):1101-1116
A gene-encoded FRET fluorescent sensor designed for detecting asymmetric dimethylation levels in vitro and in living cells.
Sun X, Chen F, Zhang L, Liu D
Analytical and bioanalytical chemistry 2023 Mar;415(8):1411-1420
Analytical and bioanalytical chemistry 2023 Mar;415(8):1411-1420
CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.
Yu XZ, Yang BW, Ao MY, Wu YK, Ye H, Wang RY, Xi MR, Hou MM
The Kaohsiung journal of medical sciences 2023 Mar;39(3):234-243
The Kaohsiung journal of medical sciences 2023 Mar;39(3):234-243
CircTNPO3 promotes hepatocellular carcinoma progression by sponging miR-199b-5p and regulating STRN expression.
Liu J, Liu B
The Kaohsiung journal of medical sciences 2023 Mar;39(3):221-233
The Kaohsiung journal of medical sciences 2023 Mar;39(3):221-233
MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335-5p signaling pathway.
Zhang K, Qiu W, Li H, Li J, Wang P, Chen Z, Lin X, Qian A
Journal of orthopaedic translation 2023 Mar;39:177-190
Journal of orthopaedic translation 2023 Mar;39:177-190
GPX4 utilization by selenium is required to alleviate cadmium-induced ferroptosis and pyroptosis in sheep kidney.
Wang L, Yang F, Hu M, Chen G, Wang Y, Xue H, Fu D, Bai H, Hu G, Cao H
Environmental toxicology 2023 Mar;38(4):962-974
Environmental toxicology 2023 Mar;38(4):962-974
PLAGL2 promotes the stemness and is upregulated by transcription factor E2F1 in human lung cancer.
Lin Y, Lin P, Guo W, Huang J, Xu X, Zhuang X
Environmental toxicology 2023 Mar;38(4):941-949
Environmental toxicology 2023 Mar;38(4):941-949
OASL knockdown inhibits the progression of stomach adenocarcinoma by regulating the mTORC1 signaling pathway.
Zhao W, Yang H, Liu L, Qu X, Ding J, Yu H, Xu B, Zhao S, Xi G, Xing L, Chai J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22824
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22824
MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.
Zhuang Y, Li T, Hu X, Xie Y, Pei X, Wang C, Li Y, Liu J, Tian Z, Zhang X, Peng L, Meng B, Wu H, Yuan W, Pan Z, Lu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22797
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22797
Glycogen synthesis kinase-3β involves in the analgesic effect of liraglutide on diabetic neuropathic pain.
Zhang Y, Zhang Q, Bai Y, Zheng H, Ji L, Zhu X, Sun W, Liu X, Zhang S, Li Y, Lu B
Journal of diabetes and its complications 2023 Mar;37(3):108416
Journal of diabetes and its complications 2023 Mar;37(3):108416
RAGE signaling pathway is involved in CUS-induced depression-like behaviors by regulating the expression of NR2A and NR2B in rat hippocampus DG.
Zhang L, Luo L, Xue L, Ran D, Yang F, Tang Q, Jiang W
Experimental neurology 2023 Mar;361:114299
Experimental neurology 2023 Mar;361:114299
Resveratrol reversed ambient particulate matter exposure-perturbed oscillations of hepatic glucose metabolism by regulating SIRT1 in mice.
Jiang J, Gu Y, Ding S, Zhang G, Ding J
Environmental science and pollution research international 2023 Mar;30(11):31821-31834
Environmental science and pollution research international 2023 Mar;30(11):31821-31834
Age-related liver endothelial zonation triggers steatohepatitis by inactivating pericentral endothelium-derived C-kit.
Duan JL, Liu JJ, Ruan B, Ding J, Fang ZQ, Xu H, Song P, Xu C, Li ZW, Du W, Xu M, Ling YW, He F, Wang L
Nature aging 2023 Mar;3(3):258-274
Nature aging 2023 Mar;3(3):258-274
PPP1R14B is a diagnostic prognostic marker in patients with uterine corpus endometrial carcinoma.
He K, Wang T, Huang X, Yang Z, Wang Z, Zhang S, Sui X, Jiang J, Zhao L
Journal of cellular and molecular medicine 2023 Mar;27(6):846-863
Journal of cellular and molecular medicine 2023 Mar;27(6):846-863
LINC01012 upregulation promotes cervical cancer proliferation and migration via downregulation of CDKN2D.
Zhang K, Ni X, Ma X, Sun R, Qiu J, Luo C
Oncology letters 2023 Mar;25(3):124
Oncology letters 2023 Mar;25(3):124
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Wu T, Zhu D, Wu X, Zhang N, Zhang Q
Oncology letters 2023 Mar;25(3):119
Oncology letters 2023 Mar;25(3):119
Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.
Zheng Y, Dai H, Chen R, Zhong Y, Zhou C, Wang Y, Zhan C, Luo J
Journal of cellular physiology 2023 Mar;238(3):582-596
Journal of cellular physiology 2023 Mar;238(3):582-596
Antiviral activity of the HSP90 inhibitor VER-50589 against enterovirus 71.
Zhu G, Wu C, Wang Q, Deng D, Lin B, Hu X, Qiu F, Li Z, Huang C, Yang Q, Zhang D
Antiviral research 2023 Mar;211:105553
Antiviral research 2023 Mar;211:105553
METTL3 alleviates D-gal-induced renal tubular epithelial cellular senescence via promoting miR-181a maturation.
Zhang Y, Ni X, Wei L, Yu Y, Zhu B, Bai Y, Pei X, Gao F, Guo L, Yong Z, Zhao W
Mechanisms of ageing and development 2023 Mar;210:111774
Mechanisms of ageing and development 2023 Mar;210:111774
Exposure to Fluoride From in Utero to Puberty Alters Gonadal Structure and Steroid Hormone Expression in Offspring Rats.
Li W, Sun Z, Li M, Yue B, Zhang X, Zhao Y, Wang J
Biological trace element research 2023 Mar;201(3):1261-1273
Biological trace element research 2023 Mar;201(3):1261-1273
High concentrate diet induced inflammatory response and tight junction disruption in the mammary gland of dairy cows.
Wang Y, Wang L, Meng M, Huo R, Ma N, Chang G, Shen X
Microbial pathogenesis 2023 Mar;176:105996
Microbial pathogenesis 2023 Mar;176:105996
On-target inhibition of Cryptosporidium parvum by nitazoxanide (NTZ) and paclitaxel (PTX) validated using a novel MDR1-transgenic host cell model and algorithms to quantify the effect on the parasite target.
Yang B, Yan Y, Wang D, Zhang Y, Yin J, Zhu G
PLoS neglected tropical diseases 2023 Mar;17(3):e0011217
PLoS neglected tropical diseases 2023 Mar;17(3):e0011217
PTEN Deficiency Facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis.
Jiang TY, Shi YY, Cui XW, Pan YF, Lin YK, Feng XF, Ding ZW, Yang C, Tan YX, Dong LW, Wang HY
Gastroenterology 2023 Mar;164(3):424-438
Gastroenterology 2023 Mar;164(3):424-438
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Zhang J, Sun Y, Sun C, Shang D
Bioorganic chemistry 2023 Mar;132:106376
Bioorganic chemistry 2023 Mar;132:106376
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of (AGTR1+) CAFs in intrahepatic cholangiocarcinoma.
Li JH, Wu X, Ni X, Li YX, Xu L, Hao XY, Zhao W, Zhu XX, Yin XY
Clinical and translational medicine 2023 Mar;13(3):e1213
Clinical and translational medicine 2023 Mar;13(3):e1213
ESE1/AGR2 axis antagonizes TGF-β-induced epithelial-mesenchymal transition in low-grade pancreatic cancer.
Xu HJ, Bai J, Tian Y, Feng X, Chen AP, Wang J, Wu J, Jin XR, Zhang F, Quan MY, Chen C, Lee KY, Zhang JS
Cancer medicine 2023 Mar;12(5):5979-5993
Cancer medicine 2023 Mar;12(5):5979-5993
hsa-mir-133a-2 promotes the proliferation and invasion of cervical cancer cells by targeting the LAMB3-mediated PI3K/ATK pathway.
Sui X, Sun Y, Zhang G, Chi N, Guan Y, Wang D, Li X
Cancer medicine 2023 Mar;12(5):5874-5888
Cancer medicine 2023 Mar;12(5):5874-5888
NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
Jiang Y, Li Y, Zhang Y, Hu D, Zhang S, Wang C, Huang S, Zhang A, Jia Z, You R
International immunopharmacology 2023 Mar;116:109847
International immunopharmacology 2023 Mar;116:109847
Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss.
Guo J, Ren R, Guo Z, Sun K, He J, Shao J, Wang X
International immunopharmacology 2023 Mar;116:109820
International immunopharmacology 2023 Mar;116:109820
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Zhang P, Lei X, Ou L, Cheng Y, Miao Q, Li C, Chen Y
International immunopharmacology 2023 Mar;116:109814
International immunopharmacology 2023 Mar;116:109814
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Yang C, Lu T, Liu M, Yuan X, Li D, Zhang J, Zhou L, Xu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
TNFα stimulates the proliferation of immature Sertoli cells by attenuating UPS-degradation of cyclin D1 and leads to the delay of BTB maturation in pubertal rats.
Wu W, Hu Y, Zhang Q, Xu Y, Su W
Andrology 2023 Mar;11(3):575-590
Andrology 2023 Mar;11(3):575-590
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.
Gong Z, Huang J, Wang D, Yang S, Ma Z, Fu Y, Ma Q, Kong W
Journal of molecular medicine (Berlin, Germany) 2023 Mar;101(3):237-248
Journal of molecular medicine (Berlin, Germany) 2023 Mar;101(3):237-248
The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia.
Pang H, Lei D, Chen T, Liu Y, Fan C
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
miR-330-3p alleviates the progression of atherosclerosis by downregulating AQP9.
Shan E, Yu Y, Tang W, Wang W, Wang X, Zhou S, Gao Y
Functional & integrative genomics 2023 Mar 7;23(2):77
Functional & integrative genomics 2023 Mar 7;23(2):77
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors.
Bai Z, Shou Z, Hu K, Yu J, Meng H, Chen C
Bone & joint research 2023 Mar 7;12(3):202-211
Bone & joint research 2023 Mar 7;12(3):202-211
Roles of glutathione peroxidase 4 on the mercury-triggered ferroptosis in renal cells: implications for the antagonism between selenium and mercury.
Chen J, Ma M, Wang R, Gao M, Hu L, Liu S, Xu M
Metallomics : integrated biometal science 2023 Mar 6;15(3)
Metallomics : integrated biometal science 2023 Mar 6;15(3)
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Zhao S, Hu S, Sun K, Luo L, Zeng L
Food & function 2023 Mar 6;14(5):2313-2325
Food & function 2023 Mar 6;14(5):2313-2325
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Lin H, Han H, Yang M, Wen Z, Chen Q, Ma Y, Wang X, Wang C, Yin T, Wang X, Lu G, Chen H, Qi J, Yang Y
European journal of medicinal chemistry 2023 Mar 5;249:115166
European journal of medicinal chemistry 2023 Mar 5;249:115166
Exosome-laden injectable self-healing hydrogel based on quaternized chitosan and oxidized starch attenuates disc degeneration by suppressing nucleus pulposus senescence.
Guan M, Liu C, Zheng Q, Chu G, Wang H, Jin J, Wu H, Chen J, Huang Q, Deng Z, Wang Y
International journal of biological macromolecules 2023 Mar 31;232:123479
International journal of biological macromolecules 2023 Mar 31;232:123479
ADCY9 functions as a novel cancer suppressor gene in lung adenocarcinoma.
Tang Y, Wang T, Zhang A, Zhu J, Zhou T, Zhou YL, Shi J
Journal of thoracic disease 2023 Mar 31;15(3):1018-1035
Journal of thoracic disease 2023 Mar 31;15(3):1018-1035
Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling.
Chen X, Lv X, Gao L, Liu J, Wang W, Guo L, Frasinyuk MS, Zhang W, Watt DS, Liu C, Liu X
Cells 2023 Mar 31;12(7)
Cells 2023 Mar 31;12(7)
Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy.
Tu Z, Wang C, Hu Q, Tao C, Fang Z, Lin L, Lei K, Luo M, Sheng Y, Long X, Li J, Wu L, Huang K, Zhu X
Journal of experimental & clinical cancer research : CR 2023 Mar 30;42(1):77
Journal of experimental & clinical cancer research : CR 2023 Mar 30;42(1):77
CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation.
Lu S, Lu T, Zhang J, Gan L, Wu X, Han D, Zhang K, Xu C, Liu S, Qin W, Yang F, Wen W
BMC cancer 2023 Mar 30;23(1):290
BMC cancer 2023 Mar 30;23(1):290
Antihepatoma peptide, scolopentide, derived from the centipede scolopendra subspinipes mutilans.
Hu YX, Liu Z, Zhang Z, Deng Z, Huang Z, Feng T, Zhou QH, Mei S, Yi C, Zhou Q, Zeng PH, Pei G, Tian S, Tian XF
World journal of gastroenterology 2023 Mar 28;29(12):1875-1898
World journal of gastroenterology 2023 Mar 28;29(12):1875-1898
Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy.
Zhu Y, Yang J, Li Y, Xu J, Fang Z
Medical oncology (Northwood, London, England) 2023 Mar 27;40(5):130
Medical oncology (Northwood, London, England) 2023 Mar 27;40(5):130
Notch-RBPJ Pathway for the Differentiation of Bone Marrow Mesenchymal Stem Cells in Femoral Head Necrosis.
Liu K, Ge H, Liu C, Jiang Y, Yu Y, Zhou Z
International journal of molecular sciences 2023 Mar 27;24(7)
International journal of molecular sciences 2023 Mar 27;24(7)
BaoShenTongLuo formula protects against podocyte injury by regulating AMPK-mediated mitochondrial biogenesis in diabetic kidney disease.
Guo Y, Wang M, Liu Y, Pang Y, Tian L, Zhao J, Liu M, Shen C, Meng Y, Wang Y, Cai Z, Zhao W
Chinese medicine 2023 Mar 26;18(1):32
Chinese medicine 2023 Mar 26;18(1):32
SLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling.
Tuomivaara ST, Teo CF, Jan YN, Jan LY, Wiita AP
bioRxiv : the preprint server for biology 2023 Mar 26;
bioRxiv : the preprint server for biology 2023 Mar 26;
Scutellarin prevents acute alcohol-induced liver injury via inhibiting oxidative stress by regulating the Nrf2/HO-1 pathway and inhibiting inflammation by regulating the AKT, p38 MAPK/NF-κB pathways.
Zhang X, Dong Z, Fan H, Yang Q, Yu G, Pan E, He N, Li X, Zhao P, Fu M, Dong J
Journal of Zhejiang University. Science. B 2023 Mar 25;24(7):617-631
Journal of Zhejiang University. Science. B 2023 Mar 25;24(7):617-631
ZNF582 overexpression restrains the progression of clear cell renal cell carcinoma by enhancing the binding of TJP2 and ERK2 and inhibiting ERK2 phosphorylation.
Yang W, Zhang Z, Li L, Zhang K, Xu Y, Xia M, Zhou J, Gong Y, Chen J, Gong K
Cell death & disease 2023 Mar 25;14(3):212
Cell death & disease 2023 Mar 25;14(3):212
ZFP281 coordinates DNMT3 and TET1 for transcriptional and epigenetic control in pluripotent state transitions.
Huang X, Balmer S, Lyu C, Xiang Y, Malik V, Wang H, Zhang Y, Xie W, Hadjantonakis AK, Zhou H, Wang J
bioRxiv : the preprint server for biology 2023 Mar 25;
bioRxiv : the preprint server for biology 2023 Mar 25;
The Expression Pattern of tRNA-Derived Small RNAs in Adult Drosophila and the Function of tRF-Trp-CCA-014-H3C4 Network Analysis.
Yang D, Xiao F, Yuan Y, Li J, Wang S, Fan X, Ni Q, Li Y, Zhang M, Gu X, Yan T, Yang M, He Z
International journal of molecular sciences 2023 Mar 24;24(7)
International journal of molecular sciences 2023 Mar 24;24(7)
GAS-STING signaling plays an essential pathogenetic role in Doxorubicin-Induced Cardiotoxicity.
Xiao Z, Yu Z, Chen C, Chen R, Su Y
BMC pharmacology & toxicology 2023 Mar 24;24(1):19
BMC pharmacology & toxicology 2023 Mar 24;24(1):19
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Cui X, Liu X, Kong P, Du T, Li T, Yang G, Zhang W, Jing X, Wang W
Aging 2023 Mar 24;15(6):2275-2292
Aging 2023 Mar 24;15(6):2275-2292
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
Zhang Y, Guo C, Yang S, Elkharti M, Liu R, Sun MZ, Liu S
Journal of clinical medicine 2023 Mar 24;12(7)
Journal of clinical medicine 2023 Mar 24;12(7)
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling.
Cao X, Wu S, Wang X, Huang J, Zhang W, Liang C
Molecular medicine (Cambridge, Mass.) 2023 Mar 23;29(1):38
Molecular medicine (Cambridge, Mass.) 2023 Mar 23;29(1):38
Low-Carbohydrate Diet Modulates Glucose-Lipid Utilization in Skeletal Muscle of Diabetic Mice.
Li Y, Yang Z, Wang Y, Fan M, Nie C, Xue L, Wang L, Qian H
Nutrients 2023 Mar 21;15(6)
Nutrients 2023 Mar 21;15(6)
Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway.
Tian Y, Che H, Yang J, Jin Y, Yu H, Wang C, Fu Y, Li N, Zhang J
Toxins 2023 Mar 21;15(3)
Toxins 2023 Mar 21;15(3)
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
Luo D, Ye W, Chen L, Yuan X, Zhang Y, Chen C, Jin X, Zhou Y
Biomedicines 2023 Mar 21;11(3)
Biomedicines 2023 Mar 21;11(3)
[Wine-processed Chuanxiong Rhizoma enhances efficacy of aumolertinib against EGFRmutant non-small cell lung cancer xenografts in nude mouse brain].
Niu W, Rong X, Zhao Q, Liu X, Xu L, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Mar 20;43(3):375-382
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Mar 20;43(3):375-382
Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.
Zhou S, Liu J, Sun Y, Xu P, Liu JL, Sun S, Zhu B, Wu H
Food & function 2023 Mar 20;14(6):2881-2895
Food & function 2023 Mar 20;14(6):2881-2895
Comparative landscape of genetic dependencies in human and chimpanzee stem cells.
She R, Fair T, Schaefer NK, Saunders RA, Pavlovic BJ, Weissman JS, Pollen AA
bioRxiv : the preprint server for biology 2023 Mar 20;
bioRxiv : the preprint server for biology 2023 Mar 20;
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
Li J, Hui Y, Xu Z, Tan J, Yin K, Kuang L, Tang Y, Wei J, Zhong Q, Zheng T
iScience 2023 Mar 17;26(3):106271
iScience 2023 Mar 17;26(3):106271
Myeloid TLR4 signaling promotes post-injury withdrawal resolution of murine liver fibrosis.
Takimoto Y, Chu PS, Nakamoto N, Hagihara Y, Mikami Y, Miyamoto K, Morikawa R, Teratani T, Taniki N, Fujimori S, Suzuki T, Koda Y, Ishihara R, Ichikawa M, Honda A, Kanai T
iScience 2023 Mar 17;26(3):106220
iScience 2023 Mar 17;26(3):106220
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
You B, Zhang T, Zhang W, Pei Y, Huang D, Lei Y, Zhang S, Qiu C, Zhang J, Gu Z, Cheng L, Chen J
iScience 2023 Mar 17;26(3):106151
iScience 2023 Mar 17;26(3):106151
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Li Z, Zeng M, Geng K, Lai D, Xu Z, Zhou W
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
HPF Modulates the Differentiation of BMSCs into HLCs and Promotes the Recovery of Acute Liver Injury in Mice.
Yang B, Luo QL, Wang N, Hu YT, Zheng WX, Li H, Maierziya M, Gu J, Wang Q
International journal of molecular sciences 2023 Mar 16;24(6)
International journal of molecular sciences 2023 Mar 16;24(6)
NDFIP1 limits cellular TAZ accumulation via exosomal sorting to inhibit NSCLC proliferation.
Cheng Y, Lu X, Li F, Chen Z, Zhang Y, Han Q, Zeng Q, Wu T, Li Z, Lu S, Williams C, Xia W
Protein & cell 2023 Mar 16;14(2):123-136
Protein & cell 2023 Mar 16;14(2):123-136
Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities.
Mastrototaro G, Carullo P, Zhang J, Scellini B, Piroddi N, Nemska S, Filomena MC, Serio S, Otey CA, Tesi C, Emrich F, Linke WA, Poggesi C, Boncompagni S, Bang ML
eLife 2023 Mar 16;12
eLife 2023 Mar 16;12
ANXA2 as a novel substrate of FBXW7 promoting esophageal squamous cell carcinoma via ERK phosphorylation.
Li Z, Pan Y, Yao J, Gao Y, Qian Y, Zheng M, Ma S
Biochemical and biophysical research communications 2023 Mar 15;649:93-100
Biochemical and biophysical research communications 2023 Mar 15;649:93-100
Transcriptional activation of CSTB gene expression by transcription factor Sp3.
Zhu W, Dong X, Luo S, Guo S, Zhou W, Song W
Biochemical and biophysical research communications 2023 Mar 15;649:71-78
Biochemical and biophysical research communications 2023 Mar 15;649:71-78
Bicuculline and Bumetanide Attenuate Sevoflurane-Induced Impairment of Myelination and Cognition in Young Mice.
Fu N, Wang Y, Zhu R, Li N, Zeng S, Miao M, Yang Y, Sun M, Zhang J
ACS chemical neuroscience 2023 Mar 15;14(6):1146-1155
ACS chemical neuroscience 2023 Mar 15;14(6):1146-1155
MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors' Efficacy in Neuroblastoma Cells.
De Rosa P, Severi F, Zadran SK, Russo M, Aloisi S, Rigamonti A, Capranico G, Milazzo G, Perini G
International journal of molecular sciences 2023 Mar 12;24(6)
International journal of molecular sciences 2023 Mar 12;24(6)
ncRNAs-mediated overexpression of STIL predict unfavorable prognosis and correlated with the efficacy of immunotherapy of hepatocellular carcinoma.
Xu L, Zhang S, Feng J, Tan D, Sun H, Guo H
Cancer cell international 2023 Mar 10;23(1):44
Cancer cell international 2023 Mar 10;23(1):44
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
Wu Y, Tang L, Huang H, Yu Q, Hu B, Wang G, Ge F, Yin T, Li S, Yu X
Nature communications 2023 Mar 10;14(1):1323
Nature communications 2023 Mar 10;14(1):1323
Glyphosate-triggered hepatocyte ferroptosis via suppressing Nrf2/GSH/GPX4 axis exacerbates hepatotoxicity.
Liu J, Yang G, Zhang H
The Science of the total environment 2023 Mar 1;862:160839
The Science of the total environment 2023 Mar 1;862:160839
Ring finger protein 10 improves pirarubicin-induced cardiac inflammation by regulating the AP-1/Meox2 signaling pathway.
Duan L, Tang H, Lan Y, Shi H, Pu P, He Q
Toxicology and applied pharmacology 2023 Mar 1;462:116411
Toxicology and applied pharmacology 2023 Mar 1;462:116411
Berbamine dihydrochloride suppresses the progression of colorectal cancer via RTKs/Akt axis.
Liu L, Liang D, Zheng Q, Zhao M, Lv R, Tang J, Chen N
Journal of ethnopharmacology 2023 Mar 1;303:116025
Journal of ethnopharmacology 2023 Mar 1;303:116025
Explore bioactive ingredients and potential mechanism of Houpo Mahuang decoction for chronic bronchitis based on UHPLC-Q exactive orbitrap HRMS, network pharmacology, and experiment verification.
Gao F, Zhang T, Zhang H, Dai Z, Gu Y, Lu M, Zhang Z, Zeng Q, Shang B, Gao S, Wang N, Xu B, Lei H
Journal of ethnopharmacology 2023 Mar 1;303:115924
Journal of ethnopharmacology 2023 Mar 1;303:115924
Integrating metabolomics and network pharmacology to investigate Panax japonicus prevents kidney injury in HFD/STZ-induced diabetic mice.
Wang T, Huang X, Zhai K, Yu J, Li J, Duan H, Liu J, Lu Z, Guo J, Li F
Journal of ethnopharmacology 2023 Mar 1;303:115893
Journal of ethnopharmacology 2023 Mar 1;303:115893
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Zhang H, Xie Z, Peng Y, Xie A, Fu C, Zheng D, Cai Z, Zhong J, Ming Q, Li M, Lu R, Liu X, Chen J
Ecotoxicology and environmental safety 2023 Mar 1;252:114630
Ecotoxicology and environmental safety 2023 Mar 1;252:114630
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
Cao WS, Zhao MJ, Chen Y, Zhu JY, Xie CF, Li XT, Geng SS, Zhong CY, Fu JY, Wu JS
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
Tang XH, Diao YG, Ren ZY, Zang YY, Zhang GF, Wang XM, Duan GF, Shen JC, Hashimoto K, Zhou ZQ, Yang JJ
Neuropharmacology 2023 Mar 1;225:109383
Neuropharmacology 2023 Mar 1;225:109383
A Novel TrxR1 Inhibitor Regulates NK and CD8+ T Cell Infiltration and Cytotoxicity, Enhancing the Efficacy of Anti-PD-1 Immunotherapy against Hepatocarcinoma.
Su X, Yin H, Bai M, Liu J, Liu R, Zeng H, Wen J
Journal of immunology (Baltimore, Md. : 1950) 2023 Mar 1;210(5):681-695
Journal of immunology (Baltimore, Md. : 1950) 2023 Mar 1;210(5):681-695
Ultrasound-mediated mesoporous silica nanoparticles loaded with PDLIM5 siRNA inhibit gefitinib resistance in NSCLC cells by attenuating EMT.
Wu H, Lv WH, Zhu YY, Jia YY, Nie F
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Mar 1;182:106372
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Mar 1;182:106372
Mrhst4 gene, coding for NAD+-dependent deacetylase is involved in citrinin production of Monascus ruber.
Hu Y, Zheng Y, Liu B, Gong Y, Shao Y
Journal of applied microbiology 2023 Mar 1;134(3)
Journal of applied microbiology 2023 Mar 1;134(3)
25-hydroxycholesterol inhibits human papillomavirus infection in cervical epithelial cells by perturbing cytoskeletal remodeling.
Li B, Hua C, Tian P, Sha Y, Zhang L, Wang Q, Lu L, Jiang S, Sui L
Journal of medical virology 2023 Jun;95(6):e28834
Journal of medical virology 2023 Jun;95(6):e28834
AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin.
Cai Z, Shen Z, Zhao J, Zhang H, Guo Z, Xia Q, Liang H, Liu J, Tan L, Sheng H, Zhu S
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2023 Jun;83(4):333-345
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2023 Jun;83(4):333-345
Effect of isorhamnetin on carbonic anhydrase IX expression and tumorigenesis of bladder cancer by activating PPARγ/PTEN/AKT pathway.
Zhang P, Sun Y, Shi L, Sun D, Wang L, Feng D, Ding C
Tissue & cell 2023 Jun;82:102048
Tissue & cell 2023 Jun;82:102048
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
Chae SA, Du M, Son JS, Zhu MJ
The Journal of physiology 2023 Jun;601(12):2371-2389
The Journal of physiology 2023 Jun;601(12):2371-2389
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Yang L, Du B, Zhang S, Wang M
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
Effects of prolonged stimulation with heated tobacco products (Ploom TECH(+) ) on gingival epithelial cells.
Uehara O, Nakamoto N, Hiraki D, Paudel D, Sugiyama N, Morikawa T, Yoshida K, Kawano Y, Shimo T, Furuichi Y, Miura H, Abiko Y
Journal of periodontal research 2023 Jun;58(3):553-563
Journal of periodontal research 2023 Jun;58(3):553-563
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Liu J, Ke P, Guo H, Gu J, Liu Y, Tian X, Wang X, Xiao F
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
A Study on the Role of Wip1 in Renal Fibrosis by Modulating Macrophage Phenotype.
Jia L, Wang Y, Ma X, Wang H, Fu R
Archives of medical research 2023 Jun;54(4):332-338
Archives of medical research 2023 Jun;54(4):332-338
taVNS Alleviates Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Via Activating Basal Forebrain Cholinergic Neurons.
Zhou Q, Zheng Z, Wang X, Li W, Wang L, Yin C, Zhang Q, Wang Q
Neurochemical research 2023 Jun;48(6):1848-1863
Neurochemical research 2023 Jun;48(6):1848-1863
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy.
Wu JC, Wang XJ, Zhu JH, Huang XY, Liu M, Qiao Z, Zhang Y, Sun Y, Wang ZY, Zhan P, Zhang T, Hu HL, Liu H, Tang W, Yi F
Acta pharmacologica Sinica 2023 Jun;44(6):1206-1216
Acta pharmacologica Sinica 2023 Jun;44(6):1206-1216
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.
Li ZB, Jiang L, Ni JD, Xu YH, Liu F, Liu WM, Wang SG, Liu ZQ, Wang CY
Acta pharmacologica Sinica 2023 Jun;44(6):1191-1205
Acta pharmacologica Sinica 2023 Jun;44(6):1191-1205
1,25-Dihydroxvitamin D3 attenuates the damage of human immortalised keratinocytes caused by Ultraviolet-B.
Wang P, Liu D, Cui J, Yan S, Liang Y, Chen Q, Liu Y, Ren S, Chen P
Cutaneous and ocular toxicology 2023 Jun;42(2):74-81
Cutaneous and ocular toxicology 2023 Jun;42(2):74-81
Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p.
Fang K, Deng Y, Yang P, Zhang Y, Luo D, Wang F, Cai Z, Liu Y
Histology and histopathology 2023 Jun;38(6):681-693
Histology and histopathology 2023 Jun;38(6):681-693
Baicalin ameliorates high fat diet-induced nonalcoholic fatty liver disease in mice via adenosine monophosphate-activated protein kinase-mediated regulation of SREBP1/Nrf2/NF-κB signaling pathways.
Gao Y, Liu J, Hao Z, Sun N, Guo J, Zheng X, Sun P, Yin W, Fan K, Li H
Phytotherapy research : PTR 2023 Jun;37(6):2405-2418
Phytotherapy research : PTR 2023 Jun;37(6):2405-2418
Characterization of the Roles of Suppressor of Cytokine Signaling-3 in Esophageal Carcinoma.
Yang X, Tian M, Lin Y, Li L, Sun X, Zhang Z, Kang M, Lin J
Human gene therapy 2023 Jun;34(11-12):495-517
Human gene therapy 2023 Jun;34(11-12):495-517
Targeting HDAC11 activity by FT895 restricts EV71 replication.
Xie H, Yang E, Wang C, Peng C, Ji L
Virus research 2023 Jun;330:199108
Virus research 2023 Jun;330:199108
Tranexamic acid may promote melanocores clustering in keratinocytes through upregulation of Rab5b.
Hu Y, Chen Y, Zhao Y, Geng Q, Guan C, Xu J, Xie B, Song X
Experimental dermatology 2023 Jun;32(6):777-786
Experimental dermatology 2023 Jun;32(6):777-786
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, Yin Y, Feng G, Lu X, Mei G, Zhang Y, Wan Q, Zhang L, Chen L
Cell death and differentiation 2023 Jun;30(6):1503-1516
Cell death and differentiation 2023 Jun;30(6):1503-1516
Bifidobacterium promotes retinal ganglion cell survival by regulating the balance of retinal glial cells.
Zhao X, Xu M, Zhao Z, Wang Y, Liu Y, Zhang T, Wan X, Jiang M, Luo X, Shen Y, Chen L, Zhou M, Wang F, Sun X
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):146-160
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):146-160
Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD.
Luan W, Wright AL, Brown-Wright H, Le S, San Gil R, Madrid San Martin L, Ling K, Jafar-Nejad P, Rigo F, Walker AK
Molecular psychiatry 2023 Jun;28(6):2445-2461
Molecular psychiatry 2023 Jun;28(6):2445-2461
Myo-Inositol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy by Inhibiting PI3K/AKT Activation.
Hu X, Yang M, Li X, Gong Z, Duan J
Journal of medicinal food 2023 Jun;26(6):368-378
Journal of medicinal food 2023 Jun;26(6):368-378
Architecture and dynamics of a desmosome-endoplasmic reticulum complex.
Bharathan NK, Giang W, Hoffman CL, Aaron JS, Khuon S, Chew TL, Preibisch S, Trautman ET, Heinrich L, Bogovic J, Bennett D, Ackerman D, Park W, Petruncio A, Weigel AV, Saalfeld S, COSEM Project Team, Wayne Vogl A, Stahley SN, Kowalczyk AP
Nature cell biology 2023 Jun;25(6):823-835
Nature cell biology 2023 Jun;25(6):823-835
1,4,5,6,7,8‑Hexahydropyrido[4,3‑d]pyrimidine inhibits HepG2 cell proliferation, migration and invasion, and induces apoptosis through the upregulation of miR‑26b‑5p by targeting CDK8.
Luo H, Yang Y, Zhou Y, Bai X, Hou Y
Oncology letters 2023 Jun;25(6):260
Oncology letters 2023 Jun;25(6):260
Ameliorative Effects of Extracellular Vesicles Derived from Mesenchymal Stem Cells on Apoptosis and Differentiation of Osteoblasts Treated with CoCl(2).
Li Q, Zhang W, Deng J, Li Q, Fu X, Kou Y, Han N
Cellular reprogramming 2023 Jun;25(3):99-108
Cellular reprogramming 2023 Jun;25(3):99-108
The mechanism of acid resistance by ornithine decarboxylase in Trichinella spiralis.
Wang S, Meng S, Yang X, Zhang B, Zhang JH, Bai ZK, Song MX
Experimental parasitology 2023 Jun;249:108503
Experimental parasitology 2023 Jun;249:108503
Jinyinqingre Oral Liquid alleviates LPS-induced acute lung injury by inhibiting the NF-κB/NLRP3/GSDMD pathway.
Wang S, Lei P, Feng Y, Jiang M, Liu Z, Shen T, Ma S, Wang L, Guo X, DU S
Chinese journal of natural medicines 2023 Jun;21(6):423-435
Chinese journal of natural medicines 2023 Jun;21(6):423-435
A Silver Compound with Potential Applications as an Anticancer, Antibacterial, Antifungal, and Anti-Alzheimer's Agent.
Korkmaz N, Kısa D, Kaplan Ö, Tosun NG, Özgür A, Imamoğlu R, Karadağ A
Chemistry & biodiversity 2023 Jun;20(6):e202300038
Chemistry & biodiversity 2023 Jun;20(6):e202300038
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Xu X, Zhang H, Li Y, Liu F, Jing Z, Ren M, Chen T, Fu Y, Wu Y, Ji P, Yang S
Materials today. Bio 2023 Jun;20:100661
Materials today. Bio 2023 Jun;20:100661
Polydopamine-cladded montmorillonite micro-sheets as therapeutic platform repair the gut mucosal barrier of murine colitis through inhibiting oxidative stress.
Lin G, Yu F, Li D, Chen Y, Zhang M, Lu K, Wang N, Hu S, Zhao Y, Xu H
Materials today. Bio 2023 Jun;20:100654
Materials today. Bio 2023 Jun;20:100654
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma.
Li H, Ge N, Guan X, Han C, Li Y, Shen L, Chen M, Zhang B, Qu C, Zou W
Steroids 2023 Jun;194:109224
Steroids 2023 Jun;194:109224
Exosomes derived from mesenchymal stromal cells promote bone regeneration by delivering miR-182-5p-inhibitor.
Zhu Q, Tang Y, Zhou T, Yang L, Zhang G, Meng Y, Zhang H, Gao J, Wang C, Su YX, Ye J
Pharmacological research 2023 Jun;192:106798
Pharmacological research 2023 Jun;192:106798
Tailor-Made Autophagy Cascade Amplification Polymeric Nanoparticles for Enhanced Tumor Immunotherapy.
Long X, Wang H, Yan J, Li Y, Dong X, Tian S, Sun Y, Luo K, He B, Liang Y
Small (Weinheim an der Bergstrasse, Germany) 2023 Jun;19(24):e2207898
Small (Weinheim an der Bergstrasse, Germany) 2023 Jun;19(24):e2207898
Vancomycin Pretreatment on MPTP-Induced Parkinson's Disease Mice Exerts Neuroprotection by Suppressing Inflammation Both in Brain and Gut.
Cui C, Hong H, Shi Y, Zhou Y, Qiao CM, Zhao WJ, Zhao LP, Wu J, Quan W, Niu GY, Wu YB, Li CS, Cheng L, Hong Y, Shen YQ
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2023 Jun;18(1-2):72-89
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2023 Jun;18(1-2):72-89
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Liu H, Xu L, Zhou L, Han W, Li Z, Liu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress.
Jiang X, Ma Y, Wang T, Zhou H, Wang K, Shi W, Qin L, Guan J, Li L, Long B, Wang J, Guan X, Ye H, Yang J, Yu Z, Jiao Z
Gastroenterology 2023 Jun;164(7):1232-1247
Gastroenterology 2023 Jun;164(7):1232-1247
Mitoquinone ameliorated airway inflammation by stabilizing β-catenin destruction complex in a steroid-insensitive asthma model.
Huang J, Chen Y, Peng X, Gong Z, Wang Y, Li Y, Xu M, Ma Y, Yu C, Cai S, Zhao W, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114680
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114680
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
Kang T, Zhang C, Lei H, Luo R, Liu M, Wang S, Zhang X, Duan Q, Xiao S, Zheng Y
The Journal of investigative dermatology 2023 Jun;143(6):977-988.e2
The Journal of investigative dermatology 2023 Jun;143(6):977-988.e2
Ginsenoside Rh4 inhibits breast cancer growth through targeting histone deacetylase 2 to regulate immune microenvironment and apoptosis.
Dong F, Qu L, Duan Z, He Y, Ma X, Fan D
Bioorganic chemistry 2023 Jun;135:106537
Bioorganic chemistry 2023 Jun;135:106537
Smad3-mediated lncRNA HSALR1 enhances the non-classic signalling pathway of TGF-β1 in human bronchial fibroblasts by binding to HSP90AB1.
Yi E, Lin B, Zhang Y, Wang X, Zhang J, Liu Y, Jin J, Hong W, Lin Z, Cao W, Mei X, Bai G, Li B, Zhou Y, Ran P
Clinical and translational medicine 2023 Jun;13(6):e1292
Clinical and translational medicine 2023 Jun;13(6):e1292
Discovery of novel exceptionally potent and orally active c-MET PROTACs for the treatment of tumors with MET alterations.
Li P, Jia C, Fan Z, Hu X, Zhang W, Liu K, Sun S, Guo H, Yang N, Zhu M, Zhuang X, Xiao J, Zheng Z, Li S
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2715-2735
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2715-2735
Hypoxic lung adenocarcinoma-derived exosomal miR-1290 induces M2 macrophage polarization by targeting SOCS3.
Gu J, Yang S, Wang X, Wu Y, Wei J, Xu J
Cancer medicine 2023 Jun;12(11):12639-12652
Cancer medicine 2023 Jun;12(11):12639-12652
Parthenolide targets NLRP3 to treat inflammasome-related diseases.
Liu L, Feng L, Gao J, Hu J, Li A, Zhu Y, Zhang C, Qiu B, Shen Z
International immunopharmacology 2023 Jun;119:110229
International immunopharmacology 2023 Jun;119:110229
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198
International immunopharmacology 2023 Jun;119:110198
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
Yang G, Liu X, Jing X, Wang J, Wang H, Chen F, Wang W, Shao Y, Cui X
International immunopharmacology 2023 Jun;119:110159
International immunopharmacology 2023 Jun;119:110159
T52 attenuates oncogenic STAT3 signaling and suppresses osteosarcoma.
Tian L, Li C, Xiang L, Zeng J, Chen S, Guo W, Chen S, Wang Y, He X, Su P, Xu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154799
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154799
Isoliquiritigenin inhibits virus replication and virus-mediated inflammation via NRF2 signaling.
Wang H, Jia X, Zhang M, Cheng C, Liang X, Wang X, Xie F, Wang J, Yu Y, He Y, Dong Q, Wang Y, Xu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154786
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154786
Ellagic acid inhibits CDK12 to increase osteoblast differentiation and alleviate osteoporosis in hindlimb-unloaded and ovariectomized mice.
Wu Z, Hu L, Ru K, Zhang W, Xu X, Liu S, Liu H, Jia Y, Liang S, Chen Z, Qian A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154745
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154745
KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway.
Li Y, Wang Y, Zou Q, Li S, Zhang F
Laboratory investigation; a journal of technical methods and pathology 2023 Jun;103(6):100078
Laboratory investigation; a journal of technical methods and pathology 2023 Jun;103(6):100078
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
Gao L, Sun Y, Zhang X, Ma D, Xie A, Wang E, Cheng L, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2206606
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2206606
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
Wu B, Shi L, Wu Y
International journal of molecular sciences 2023 Jun 9;24(12)
International journal of molecular sciences 2023 Jun 9;24(12)
Inhibition of CPEB3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs, and enhances object location memory.
Chen CC, Han J, Chinn CA, Rounds JS, Li X, Nikan M, Myszka M, Tong L, Passalacqua LFM, Bredy TW, Wood MA, Lupták A
bioRxiv : the preprint server for biology 2023 Jun 9;
bioRxiv : the preprint server for biology 2023 Jun 9;
The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study.
E Y, Yu Q, Sun T, Xue H, Zhao XR, Zheng HC
BMC cancer 2023 Jun 8;23(1):520
BMC cancer 2023 Jun 8;23(1):520
Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Fan S, Yan Y, Xia Y, Zhou Z, Luo L, Zhu M, Han Y, Yao D, Zhang L, Fang M, Peng L, Yu J, Liu Y, Gao X, Guan H, Li H, Wang C, Wu X, Zhu H, Cao Y, Huang C
Nature communications 2023 Jun 8;14(1):3368
Nature communications 2023 Jun 8;14(1):3368
Curcumin Attenuates Periodontal Injury via Inhibiting Ferroptosis of Ligature-Induced Periodontitis in Mice.
Wang Y, Lin H, Huang W, Liu Z, Chen Z, Zhao X, Ding T, Qin W, Shen Y
International journal of molecular sciences 2023 Jun 7;24(12)
International journal of molecular sciences 2023 Jun 7;24(12)
MicroRNA-29a-3p prevents Schistosoma japonicum-induced liver fibrosis by targeting Roundabout homolog 1 in hepatic stellate cells.
Kong H, Song Q, Hu W, Guo S, Xiang D, Huang S, Xu X, He J, Pan L, Tao R, Yu H, Huang J
Parasites & vectors 2023 Jun 6;16(1):184
Parasites & vectors 2023 Jun 6;16(1):184
Lycopene ameliorates islet function and down-regulates the TLR4/MyD88/NF-κB pathway in diabetic mice and Min6 cells.
Liu Y, Tian Y, Dai X, Liu T, Zhang Y, Wang S, Shi H, Yin J, Xu T, Zhu R, Zhang Y, Zhao D, Gao S, Wang XD, Wang L, Zhang D
Food & function 2023 Jun 6;14(11):5090-5104
Food & function 2023 Jun 6;14(11):5090-5104
LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma.
Meng K, Lu S, Li YY, Hu LL, Zhang J, Cao Y, Wang Y, Zhang CZ, He QY
EMBO reports 2023 Jun 5;24(6):e56282
EMBO reports 2023 Jun 5;24(6):e56282
PACAP6-38 improves nitroglycerin-induced central sensitization by modulating synaptic plasticity at the trigeminal nucleus caudalis in a male rat model of chronic migraine.
Zhang L, Zhou Y, Yang L, Wang Y, Xiao Z
The journal of headache and pain 2023 Jun 5;24(1):66
The journal of headache and pain 2023 Jun 5;24(1):66
Risk signature identification and NPRL2 affects sunitinib sensitivity in clear cell renal cell carcinoma.
Du X, Zhao Z, Zhao X, Wang H, Jiang L, Tang W
Biochemical and biophysical research communications 2023 Jun 30;663:122-131
Biochemical and biophysical research communications 2023 Jun 30;663:122-131
Aspartoacylase promotes the process of tumour development and is associated with immune infiltrates in gastric cancer.
Han Y, Wang X, Xu M, Teng Z, Qin R, Tan G, Li P, Sun P, Liu H, Chen L, Jia B
BMC cancer 2023 Jun 30;23(1):604
BMC cancer 2023 Jun 30;23(1):604
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Jiang L, Liu Y, Pan Y, Tan Z, Wang J, Zheng G, Qian C, Xu S, Zhu X, Ma W, Guerrini S, Infante-Cossio P, Wu J, Ge M, Cai X
Gland surgery 2023 Jun 30;12(6):834-852
Gland surgery 2023 Jun 30;12(6):834-852
Carbonic anhydrase IX inhibitor S4 triggers release of DAMPs related to immunogenic cell death in glioma cells via endoplasmic reticulum stress pathway.
Cui J, Xu H, Shi J, Fang K, Liu J, Liu F, Chen Y, Liang H, Zhang Y, Piao H
Cell communication and signaling : CCS 2023 Jun 29;21(1):167
Cell communication and signaling : CCS 2023 Jun 29;21(1):167
Neurokinin-1 receptor drives PKCɑ-AURKA/N-Myc signaling to facilitate the neuroendocrine progression of prostate cancer.
Zhang XW, Li JY, Li L, Hu WQ, Tao Y, Gao WY, Ye ZN, Jia HY, Wang JN, Miao XK, Yang WL, Wang R, Mou LY
Cell death & disease 2023 Jun 29;14(6):384
Cell death & disease 2023 Jun 29;14(6):384
Panaxytriol upregulates CYP3A4 expression through the interaction between nuclear regulators and DNA response elements.
Yan J, Gu Q, Meng C, Liu J, Liu F, Xia C
Journal of ethnopharmacology 2023 Jun 28;310:116398
Journal of ethnopharmacology 2023 Jun 28;310:116398
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8(+) T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
Li P, Zhou D, Chen D, Cheng Y, Chen Y, Lin Z, Zhang X, Huang Z, Cai J, Huang W, Lin Y, Ke H, Long J, Zou Y, Ye S, Lan P
Journal of biomedical science 2023 Jun 28;30(1):47
Journal of biomedical science 2023 Jun 28;30(1):47
A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition.
Wang Y, Li Y, Liu D, Zheng D, Li X, Li C, Huang C, Wang Y, Wang X, Li Q, Xu J
Molecules (Basel, Switzerland) 2023 Jun 28;28(13)
Molecules (Basel, Switzerland) 2023 Jun 28;28(13)
Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis.
Liu X, Jiang L, Zhang W, Zhang J, Luan X, Zhan Y, Wang T, Da J, Liu L, Zhang S, Guo Y, Zhang K, Wang Z, Miao N, Xie X, Liu P, Li Y, Jin H, Zhang B
Journal of translational medicine 2023 Jun 27;21(1):417
Journal of translational medicine 2023 Jun 27;21(1):417
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
Dey G, Bharti R, Braley C, Alluri R, Esakov E, Crean-Tate K, McCrae K, Joehlin-Price A, Rose PG, Lathia J, Gong Z, Reizes O
Journal of ovarian research 2023 Jun 27;16(1):122
Journal of ovarian research 2023 Jun 27;16(1):122
ICP4-Associated Activation of Rap1b Facilitates Herpes Simplex Virus Type I (HSV-1) Infection in Human Corneal Epithelial Cells.
Zhang B, Ding J, Ma Z
Viruses 2023 Jun 27;15(7)
Viruses 2023 Jun 27;15(7)
Identification of TIMP1 as an inflammatory biomarker associated with temporal lobe epilepsy based on integrated bioinformatics and experimental analyses.
He Y, Zhang H, Ma L, Li J, Wang F, Zhou H, Zhang G, Wen Y
Journal of neuroinflammation 2023 Jun 26;20(1):151
Journal of neuroinflammation 2023 Jun 26;20(1):151
Identification of potential biomarkers for idiopathic pulmonary fibrosis and validation of TDO2 as a potential therapeutic target.
Wang R, Yang YM
World journal of cardiology 2023 Jun 26;15(6):293-308
World journal of cardiology 2023 Jun 26;15(6):293-308
S-Palmitoylation of the serotonin transporter promotes its cell surface expression and serotonin uptake.
Harada K, Sho R, Takakura H, Yokoyama E, Koyama R, Yamamoto Y, Adachi N, Tanaka S, Hide I, Sakai N
Biochemical and biophysical research communications 2023 Jun 25;662:58-65
Biochemical and biophysical research communications 2023 Jun 25;662:58-65
Synergism Antiproliferative Effects of Apigenin and Naringenin in NSCLC Cells.
Liu X, Zhao T, Shi Z, Hu C, Li Q, Sun C
Molecules (Basel, Switzerland) 2023 Jun 23;28(13)
Molecules (Basel, Switzerland) 2023 Jun 23;28(13)
METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing.
Wang X, Wang J, Zhao X, Wu H, Li J, Cheng Y, Guo Q, Cao X, Liang T, Sun L, Zhang G
Journal of translational medicine 2023 Jun 23;21(1):407
Journal of translational medicine 2023 Jun 23;21(1):407
Syntabulin regulates neuronal excitation/inhibition balance and epileptic seizures by transporting syntaxin 1B.
Ke P, Gu J, Liu J, Liu Y, Tian X, Ma Y, Meng Y, Xiao F
Cell death discovery 2023 Jun 22;9(1):187
Cell death discovery 2023 Jun 22;9(1):187
TNIP2 inhibits amyloidogenesis by regulating the 3'UTR of BACE1: An in vitro study.
Chen L, Wang L, Zhou GF, Liu Y, Chen X, Xie XY, Wen QX, Li CL, Yang J, Chen GJ
Neuroscience letters 2023 Jun 21;808:137265
Neuroscience letters 2023 Jun 21;808:137265
Histone Deacetylase Inhibition and Autophagy Modulation Induces a Synergistic Antiproliferative Effect and Cell Death in Cholangiocarcinoma Cells.
Yenigül M, Gencer Akçok EB
ACS omega 2023 Jun 20;8(24):21755-21768
ACS omega 2023 Jun 20;8(24):21755-21768
Microcystin-LR-Exposure-Induced Kidney Damage by Inhibiting MKK6-Mediated Mitophagy in Mice.
Yao X, Liu Y, Yang Y, Li Y, Hu N, Song F, Yang F
Toxins 2023 Jun 19;15(6)
Toxins 2023 Jun 19;15(6)
SMYD2 inhibition-mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity.
Tang M, Chen G, Tu B, Hu Z, Huang Y, DuFort CC, Wan X, Mao Z, Liu Y, Zhu WG, Lu W
Science advances 2023 Jun 16;9(24):eade6624
Science advances 2023 Jun 16;9(24):eade6624
An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay.
Lin XT, Zhang J, Xie CM
STAR protocols 2023 Jun 16;4(2):102199
STAR protocols 2023 Jun 16;4(2):102199
A novel co-target of ACY1 governing plasma membrane translocation of SphK1 contributes to inflammatory and neuropathic pain.
Liu B, Wu W, Cui L, Zheng X, Li N, Zhang X, Duan G
iScience 2023 Jun 16;26(6):106989
iScience 2023 Jun 16;26(6):106989
Antioxidant Peptides from Monkfish Swim Bladders: Ameliorating NAFLD In Vitro by Suppressing Lipid Accumulation and Oxidative Stress via Regulating AMPK/Nrf2 Pathway.
Wu MF, Xi QH, Sheng Y, Wang YM, Wang WY, Chi CF, Wang B
Marine drugs 2023 Jun 16;21(6)
Marine drugs 2023 Jun 16;21(6)
Genetically Encoded Aminocoumarin Lysine for Optical Control of Protein-Nucleotide Interactions in Zebrafish Embryos.
Brown W, Wesalo J, Samanta S, Luo J, Caldwell SE, Tsang M, Deiters A
ACS chemical biology 2023 Jun 16;18(6):1305-1314
ACS chemical biology 2023 Jun 16;18(6):1305-1314
Mettl3-mediated m(6)A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Dai G, Huang S, Li Y, Tu X, Xia J, Zhou Z, Chen W, Zhang A, Lin J, Li Y, He D, Lin T, Cong J, Lei Y, Han L, Yao Z, Liu W, Zhou Y, Li Q, Li J, Zhang Y, Wu A, Xiao D, Wang W, Zhao W, Jia J, Lin X
Aging 2023 Jun 16;15(12):5550-5568
Aging 2023 Jun 16;15(12):5550-5568
Trim65 attenuates isoproterenol-induced cardiac hypertrophy by promoting autophagy and ameliorating mitochondrial dysfunction via the Jak1/Stat1 signaling pathway.
Liu H, Zhou Z, Deng H, Tian Z, Wu Z, Liu X, Ren Z, Jiang Z
European journal of pharmacology 2023 Jun 15;949:175735
European journal of pharmacology 2023 Jun 15;949:175735
Baicalin inhibited both the Furin/TGFβ1/Smad3/TSP-1 pathway in endothelial cells and the AKT/Ca(2+)/ROS pathway in platelets to ameliorate inflammatory coagulopathy.
Wang P, Wu J, Wang Q, Zhuang S, Zhao J, Yu Y, Zhang W, Zheng Y, Liu X
European journal of pharmacology 2023 Jun 15;949:175674
European journal of pharmacology 2023 Jun 15;949:175674
Thallium exposure induces changes in B and T cell generation in mice.
Li D, Li L, Yao H, Su Q, Ye J
Toxicology 2023 Jun 15;492:153532
Toxicology 2023 Jun 15;492:153532
A multi-bioresponsive self-assembled nano drug delivery system based on hyaluronic acid and geraniol against liver cancer.
Duan S, Xia Y, Tian X, Cui J, Zhang X, Yang Q, Zhao T, Lin Y, Zhang F, Zhang X, Cen J
Carbohydrate polymers 2023 Jun 15;310:120695
Carbohydrate polymers 2023 Jun 15;310:120695
Cigarette smoke triggers calcium overload in mouse hippocampal neurons via the ΔFOSB-CACNA2D1 axis to impair cognitive performance.
Zhang H, Zhou H, Guo X, Zhang G, Xiao M, Wu S, Jin C, Yang J, Lu X
Ecotoxicology and environmental safety 2023 Jun 15;258:114996
Ecotoxicology and environmental safety 2023 Jun 15;258:114996
Perfluoroalkyl substances promote breast cancer progression via ERα and GPER mediated PI3K/Akt and MAPK/Erk signaling pathways.
Liu Q, Liu Y, Li X, Wang D, Zhang A, Pang J, He J, Chen X, Tang NJ
Ecotoxicology and environmental safety 2023 Jun 15;258:114980
Ecotoxicology and environmental safety 2023 Jun 15;258:114980
Young Sca-1(+) bone marrow stem cell-derived exosomes preserve visual function via the miR-150-5p/MEKK3/JNK/c-Jun pathway to reduce M1 microglial polarization.
Wang Y, Qin WY, Wang Q, Liu XN, Li XH, Ye XQ, Bai Y, Zhang Y, Liu P, Wang XL, Zhou YH, Yuan HP, Shao ZB
Journal of nanobiotechnology 2023 Jun 15;21(1):194
Journal of nanobiotechnology 2023 Jun 15;21(1):194
Disinhibition of Mesolimbic Dopamine Circuit by the Lateral Hypothalamus Regulates Pain Sensation.
Ma Y, Zhao W, Chen D, Zhou D, Gao Y, Bian Y, Xu Y, Xia SH, Fang T, Yang JX, Song L, Liu H, Ding HL, Zhang H, Cao JL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Jun 14;43(24):4525-4540
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Jun 14;43(24):4525-4540
cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8(+) T cell function and anti-tumor immunity.
Zhao Y, Caron C, Chan YY, Lee CK, Xu X, Zhang J, Masubuchi T, Wu C, Bui JD, Hui E
Immunity 2023 Jun 13;56(6):1187-1203.e12
Immunity 2023 Jun 13;56(6):1187-1203.e12
Sparganii Rhizoma alleviates pulmonary fibrosis by inhibiting fibroblasts differentiation and epithelial-mesenchymal transition mediated by TGF-β1/ Smad2/3 pathway.
Liu J, Gao D, Ding Q, Zhang B, Zhu W, Shi Y
Journal of ethnopharmacology 2023 Jun 12;309:116305
Journal of ethnopharmacology 2023 Jun 12;309:116305
Phase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer.
Zhao S, Zhuang W, Han B, Song Z, Guo W, Luo F, Wu L, Hu Y, Wang H, Dong X, Jiang D, Wang M, Miao L, Wang Q, Zhang J, Fu Z, Huang Y, Xu C, Hu L, Li L, Hu R, Yang Y, Li M, Yang X, Zhang L, Huang Y, Fang W
Nature communications 2023 Jun 12;14(1):3468
Nature communications 2023 Jun 12;14(1):3468
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Zhang L, Pan Q, Wu Y, Zhang P, Li S, Xu Y, Li D, Zheng M, Pei D, Wang Q
Experimental cell research 2023 Jun 1;427(1):113601
Experimental cell research 2023 Jun 1;427(1):113601
Blunting ROS/TRPML1 pathway protects AFB1-induced porcine intestinal epithelial cells apoptosis by restoring impaired autophagic flux.
Cheng X, Liang J, Wu D, Guo X, Cao H, Zhang C, Liu P, Hu R, Hu G, Zhuang Y
Ecotoxicology and environmental safety 2023 Jun 1;257:114942
Ecotoxicology and environmental safety 2023 Jun 1;257:114942
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Li X, Wang W, Hou Y, Li G, Yi H, Cui S, Zhang J, He X, Zhao H, Yang Z, Qiu Y, Liu Z, Xie J
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.
Dai L, Gao F, Wang Q, Lv X, Cheng Z, Wu Y, Chai X, Zetterberg H, Blennow K, Levey AI, Shi J, Shen Y, CANDI Consortium
Journal of neurology, neurosurgery, and psychiatry 2023 Jul;94(7):550-559
Journal of neurology, neurosurgery, and psychiatry 2023 Jul;94(7):550-559
Proteomics reveals defective peroxisomal fatty acid oxidation during the progression of acute kidney injury and repair.
Chen J, Zheng QY, Wang LM, Luo J, Chen KH, He YN
Heliyon 2023 Jul;9(7):e18134
Heliyon 2023 Jul;9(7):e18134
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes.
Yang Y, Fu X, Xia B, Zhou L, Zhang H, Li C, Ye X, Liu T
Heliyon 2023 Jul;9(7):e17891
Heliyon 2023 Jul;9(7):e17891
TEA Domain Transcription Factor 1 Inhibits Ferroptosis and Sorafenib Sensitivity of Hepatocellular Carcinoma Cells.
Li H, Lan H, Zhang M, Zhao F, An N, Yi C
Digestive diseases and sciences 2023 Jul;68(7):3070-3082
Digestive diseases and sciences 2023 Jul;68(7):3070-3082
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Kong Y, Wu M, Wan X, Sun M, Zhang Y, Wu Z, Li C, Liang X, Gao L, Ma C, Yue X
Redox biology 2023 Jul;63:102732
Redox biology 2023 Jul;63:102732
LATS-regulated nuclear-cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial-mesenchymal transition.
Zhang F, Gao J, Liu X, Sun Y, Liu L, Hu B, Wang Z, Shi J, Guo W, Zhang S
Molecular carcinogenesis 2023 Jul;62(7):963-974
Molecular carcinogenesis 2023 Jul;62(7):963-974
Ubiquitin ligase MARCH8 promotes the malignant progression of hepatocellular carcinoma through PTEN ubiquitination and degradation.
Xu Y, Zhang D, Ji J, Zhang L
Molecular carcinogenesis 2023 Jul;62(7):1062-1072
Molecular carcinogenesis 2023 Jul;62(7):1062-1072
Long noncoding RNA MAPKAPK5-AS1 promotes metastasis through regulation miR-376b-5p/ECT2 axis in hepatocellular carcinoma.
Lv E, Sheng J, Yu C, Rao D, Huang W
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Jul;55(7):945-954
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Jul;55(7):945-954
Molecular characterization of wild-type and HSAN2B-linked FAM134B.
Kanamori A, Hinaga S, Hirata Y, Amaya F, Oh-Hashi K
Molecular biology reports 2023 Jul;50(7):6005-6017
Molecular biology reports 2023 Jul;50(7):6005-6017
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.
Zou X, Liu C, Huang Z, Xiang S, Li K, Yuan Y, Hao Y, Zhou F
Molecular biology reports 2023 Jul;50(7):5667-5674
Molecular biology reports 2023 Jul;50(7):5667-5674
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.
Qian L, Li N, Lu XC, Xu M, Liu Y, Li K, Zhang Y, Hu K, Qi YT, Yao J, Wu YL, Wen W, Huang S, Chen ZJ, Yin M, Lei QY
Nature metabolism 2023 Jul;5(7):1159-1173
Nature metabolism 2023 Jul;5(7):1159-1173
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Ren G, Lv W, Ding Y, Wang L, Cui Z, Li R, Tian J, Zhang C
Journal of ginseng research 2023 Jul;47(4):543-551
Journal of ginseng research 2023 Jul;47(4):543-551
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Liang JP, He YM, Cui YL, Sun YN, He GS, Zhu ZG, Mao XL
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
Enhancement of CAR-T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins.
Qiao Y, Chen J, Wang X, Yan S, Tan J, Xia B, Chen Y, Lin K, Zou F, Liu B, He X, Zhang Y, Zhang X, Zhang H, Wu X, Lu L
Cancer communications (London, England) 2023 Jul;43(7):788-807
Cancer communications (London, England) 2023 Jul;43(7):788-807
Lysophosphatidylcholine facilitates the pathogenesis of psoriasis through activating keratinocytes and T cells differentiation via glycolysis.
Liu P, Zhou Y, Chen C, Yan B, Li L, Zhu W, Li J, Chen M, Su J, Kuang Y, Chen X, Peng C
Journal of the European Academy of Dermatology and Venereology : JEADV 2023 Jul;37(7):1344-1360
Journal of the European Academy of Dermatology and Venereology : JEADV 2023 Jul;37(7):1344-1360
Erythropoietin ameliorates cognitive dysfunction in mice with type 2 diabetes mellitus via inhibiting iron overload and ferroptosis.
Guo T, Yu Y, Yan W, Zhang M, Yi X, Liu N, Cui X, Wei X, Sun Y, Wang Z, Shang J, Cui W, Chen L
Experimental neurology 2023 Jul;365:114414
Experimental neurology 2023 Jul;365:114414
Direct Knockdown of PDZ and LIM Domain 1 Using an Adenoviral Delivery System Accelerates Osteogenesis and Fracture Healing in Mice.
Chen Z, Zhao Q, Zhang R, Chen L, Gao S, Wang Y, Li T, Xue J
Human gene therapy 2023 Jul;34(13-14):649-661
Human gene therapy 2023 Jul;34(13-14):649-661
Cathepsin B S-nitrosylation promotes ADAR1-mediated editing of its own mRNA transcript via an ADD1/MATR3 regulatory axis.
Lin Z, Zhao S, Li X, Miao Z, Cao J, Chen Y, Shi Z, Zhang J, Wang D, Chen S, Wang L, Gu A, Chen F, Yang T, Sun K, Han Y, Xie L, Chen H, Ji Y
Cell research 2023 Jul;33(7):546-561
Cell research 2023 Jul;33(7):546-561
NKAP acts with HDAC3 to prevent R-loop associated genome instability.
Zhang X, Duan J, Li Y, Jin X, Wu C, Yang X, Lu W, Ge W
Cell death and differentiation 2023 Jul;30(7):1811-1828
Cell death and differentiation 2023 Jul;30(7):1811-1828
African swine fever virus pS273R antagonizes stress granule formation by cleaving the nucleating protein G3BP1 to facilitate viral replication.
Li T, Li X, Wang X, Chen X, Zhao G, Liu C, Bao M, Song J, Li J, Huang L, Rong J, Tian K, Deng J, Zhu J, Cai X, Bu Z, Zheng J, Weng C
The Journal of biological chemistry 2023 Jul;299(7):104844
The Journal of biological chemistry 2023 Jul;299(7):104844
Co-phase separation of Y14 and RNA in vitro and its implication for DNA repair.
Yu CL, Chuang TW, Samuel SY, Lou YC, Tarn WY
RNA (New York, N.Y.) 2023 Jul;29(7):1007-1019
RNA (New York, N.Y.) 2023 Jul;29(7):1007-1019
Periostin regulates LPS-induced apoptosis via Nrf2/HO-1 pathway in periodontal ligament fibroblasts.
Jiang Y, Yang P, Li C, Lu Y, Kou Y, Liu H, Guo J, Li M
Oral diseases 2023 Jul;29(5):2188-2204
Oral diseases 2023 Jul;29(5):2188-2204
Sialin mediates submandibular gland regeneration ability by affecting polysialic acid synthesis.
Wang B, Li Z, Li J, Shao Q, Qin L
Oral diseases 2023 Jul;29(5):2096-2106
Oral diseases 2023 Jul;29(5):2096-2106
Transforming acidic coiled-coil containing protein 3 suppresses influenza A virus replication by impeding viral endosomal trafficking and nuclear import.
Deng L, Zhao L, Jin J, Qiao B, Zhang X, Chang L, Zheng L, Dankar S, Ping J
Veterinary microbiology 2023 Jul;282:109769
Veterinary microbiology 2023 Jul;282:109769
ORP5 promotes migration and invasion of cervical cancer cells by inhibiting endoplasmic reticulum stress.
Wu Y, Min L, Zhang P, Zhang L, Xu Y, Li D, Zheng M, Pei D, Wang Q
Cell stress & chaperones 2023 Jul;28(4):395-407
Cell stress & chaperones 2023 Jul;28(4):395-407
Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells.
Chen F, Cen H, Mao D, Feng R
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Analysis and validation of the potential of the MYO1E gene in pancreatic adenocarcinoma based on a bioinformatics approach.
Liu S, Liu P, Fei X, Zhu C, Hou J, Wang X, Pan Y
Oncology letters 2023 Jul;26(1):285
Oncology letters 2023 Jul;26(1):285
Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis.
Zhou YX, Wei J, Deng G, Hu A, Sun PY, Zhao X, Song BL, Luo J
Nature cell biology 2023 Jul;25(7):937-949
Nature cell biology 2023 Jul;25(7):937-949
The prognostic value of DAAM2 in lower grade glioma, liver cancer, and breast cancer.
Li Z, Wei X, Zhu Y
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Jul;25(7):2224-2238
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Jul;25(7):2224-2238
Host factor DUSP5 potently inhibits dengue virus infection by modulating cytoskeleton rearrangement.
Liang M, Li Y, Zhang K, Zhu Y, Liang J, Liu M, Zhang S, Chen D, Liang H, Liang L, An S, Zhu X, He Z
Antiviral research 2023 Jul;215:105622
Antiviral research 2023 Jul;215:105622
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Man J, Zhou W, Zuo S, Zhao X, Wang Q, Ma H, Li HY
Biochemical pharmacology 2023 Jul;213:115615
Biochemical pharmacology 2023 Jul;213:115615
Oncogenic BRAF(V600E) induces microglial proliferation through extracellular signal-regulated kinase and neuronal death through c-Jun N-terminal kinase.
Ye Q, Srivastava P, Al-Kuwari N, Chen X
Neural regeneration research 2023 Jul;18(7):1613-1622
Neural regeneration research 2023 Jul;18(7):1613-1622
Novel antiosteoporotic peptides purified from protein hydrolysates of taihe black-boned silky fowl: By larval zebrafish model and molecular docking.
Qiu Y, Ying J, Yan F, Yu H, Zhao Y, Li H, Xia S, Chen J, Zhu J
Food research international (Ottawa, Ont.) 2023 Jul;169:112850
Food research international (Ottawa, Ont.) 2023 Jul;169:112850
The Apelin/APJ system modulates seizure activity and endocytosis of the NMDA receptor GluN2B subunit.
Zhang X, Gu Y, Ma Y, Wu J, Chen Y, Tao K, Sun H, Liu Z, Wang X, Tian X
Neurochemistry international 2023 Jul;167:105545
Neurochemistry international 2023 Jul;167:105545
Tissue Inhibitor of Metalloproteinase-1 Enhances Eosinophilic Airway Inflammation in Severe Asthma.
Cao TBT, Quoc QL, Yang EM, Moon JY, Shin YS, Ryu MS, Choi Y, Park HS
Allergy, asthma & immunology research 2023 Jul;15(4):451-472
Allergy, asthma & immunology research 2023 Jul;15(4):451-472
Knockdown of Cadherin 26 Prevents the Inflammatory Responses of Allergic Rhinitis.
Liu T, Sun Y, Guo Z, Bai W
The Laryngoscope 2023 Jul;133(7):1558-1567
The Laryngoscope 2023 Jul;133(7):1558-1567
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
Xiao C, Li Q, Xiao J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2023 Jul;120:110318
International immunopharmacology 2023 Jul;120:110318
Tongue-Brain-Transported ZnO Nanoparticles Induce Abnormal Taste Perception.
Chen A, Wang R, Kang Y, Liu J, Wu J, Zhang Y, Zhang Y, Shao L
Advanced healthcare materials 2023 Jul;12(17):e2203316
Advanced healthcare materials 2023 Jul;12(17):e2203316
Myricetin improves pathological changes in 3×Tg-AD mice by regulating the mitochondria-NLRP3 inflammasome-microglia channel by targeting P38 MAPK signaling pathway.
Liu P, Zhou Y, Shi J, Wang F, Yang X, Zheng X, Wang Y, He Y, Xie X, Pang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154801
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154801
Functional recovery of myocardial infarction by specific EBP-PR1P peptides bridging injectable cardiac extracellular matrix and vascular endothelial growth factor.
Cao W, Zhang H, Zhou N, Zhou R, Zhang X, Yin J, Deng J, Ao X, Shi C
Journal of biomedical materials research. Part A 2023 Jul;111(7):995-1005
Journal of biomedical materials research. Part A 2023 Jul;111(7):995-1005
Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response.
Yang W, Wang Y, Wang T, Li C, Shi L, Zhang P, Yin Y, Tao K, Li R
Genes & diseases 2023 Jul;10(4):1552-1563
Genes & diseases 2023 Jul;10(4):1552-1563
Targeting L-Selectin Lymphocytes to Deliver Immunosuppressive Drug in Lymph Nodes for Durable Multiple Sclerosis Treatment.
Zhao Y, Zhang J, Cheng X, Huang W, Shen S, Wu S, Huang Y, Nie G, Wang H, Qiu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(20):e2300738
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(20):e2300738
Targeting Autophagy With the Synergistic Combination of Chloroquine and Rapamycin as a Novel Effective Treatment for Well-differentiated Liposarcoma.
Masaki N, Aoki Y, Obara K, Kubota Y, Bouvet M, Miyazaki J, Hoffman RM
Cancer genomics & proteomics 2023 Jul-Aug;20(4):317-322
Cancer genomics & proteomics 2023 Jul-Aug;20(4):317-322
Glucose-induced CRL4(COP1)-p53 axis amplifies glycometabolism to drive tumorigenesis.
Su Y, Luo Y, Zhang P, Lin H, Pu W, Zhang H, Wang H, Hao Y, Xiao Y, Zhang X, Wei X, Nie S, Zhang K, Fu Q, Chen H, Huang N, Ren Y, Wu M, Chow BKC, Chen X, Jin W, Wang F, Zhao L, Rao F
Molecular cell 2023 Jul 6;83(13):2316-2331.e7
Molecular cell 2023 Jul 6;83(13):2316-2331.e7
Comparative landscape of genetic dependencies in human and chimpanzee stem cells.
She R, Fair T, Schaefer NK, Saunders RA, Pavlovic BJ, Weissman JS, Pollen AA
Cell 2023 Jul 6;186(14):2977-2994.e23
Cell 2023 Jul 6;186(14):2977-2994.e23
Fibrin glue delivery system containing rhein ameliorates intervertebral disc degeneration by anti-inflammatory efficacy.
Bao J, Gao W, Zhang W, Wang D, Pan H
Journal of orthopaedic surgery and research 2023 Jul 6;18(1):485
Journal of orthopaedic surgery and research 2023 Jul 6;18(1):485
High-throughput identification of regulatory elements and functional assays to uncover susceptibility genes for nasopharyngeal carcinoma.
Wang TM, Xiao RW, He YQ, Zhang WL, Diao H, Tang M, Mai ZM, Xue WQ, Yang DW, Deng CM, Liao Y, Zhou T, Li DH, Wu YX, Chen XY, Zhang J, Li XZ, Zhang PF, Zheng XH, Zhang SD, Hu YZ, Cai Y, Zheng Y, Zhang Z, Zhou Y, Jin G, Bei J, Mai HQ, Sun Y, Ma J, Hu Z, Liu J, Lung ML, Adami HO, Ye W, Lam TH, Shen H, Jia WH
American journal of human genetics 2023 Jul 6;110(7):1162-1176
American journal of human genetics 2023 Jul 6;110(7):1162-1176
DSPE-PEG polymer enhanced berberine absorption specifically in the small intestine of rats through paracellular passway.
Gao Y, Sun J, Wang S, Huxiao L, Xu Y, Zhang H
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):931-939
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):931-939
Expression and Activity of the Transcription Factor CCAAT/Enhancer-Binding Protein β (C/EBPβ) Is Regulated by Specific Pulse-Modulated Radio Frequencies in Oligodendroglial Cells.
Huang B, Zhao W, Cai X, Zhu Y, Lu Y, Zhao J, Xiang N, Wang X, Deng H, Tang X, Liu L, Zhao Y, Shi Y
International journal of molecular sciences 2023 Jul 5;24(13)
International journal of molecular sciences 2023 Jul 5;24(13)
FTO-dependent m(6)A regulates muscle fiber remodeling in an NFATC1-YTHDF2 dependent manner.
Wang W, Du X, Luo M, Yang N
Clinical epigenetics 2023 Jul 5;15(1):109
Clinical epigenetics 2023 Jul 5;15(1):109
Development of Woolly Hair and Hairlessness in a CRISPR-Engineered Mutant Mouse Model with KRT71 Mutations.
Zhang T, Yao H, Wang H, Sui T
Cells 2023 Jul 5;12(13)
Cells 2023 Jul 5;12(13)
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
Li D, Liu Y, Zhan Q, Zeng Y, Peng Z, He Q, Tan Q, Cao W, Wang S, Wang J
Cells 2023 Jul 4;12(13)
Cells 2023 Jul 4;12(13)
LHPP suppresses proliferation, migration, and invasion in hepatocellular carcinoma and pancreatic cancer by inhibiting EGFR signaling pathway.
Zhu H, Song C, Li J, Liu Q, Liu M, Fu L
Medical oncology (Northwood, London, England) 2023 Jul 31;40(9):257
Medical oncology (Northwood, London, England) 2023 Jul 31;40(9):257
Ginsenoside-Rg1 synergized with voluntary running exercise protects against glial activation and dysregulation of neuronal plasticity in depression.
Wang W, Wang L, Wang L, Li Y, Lan T, Wang C, Chen X, Chen S, Yu S
Food & function 2023 Jul 31;14(15):7222-7239
Food & function 2023 Jul 31;14(15):7222-7239
Multi-omics reveals that green pea (Pisum sativum L.) hull supplementation ameliorates non-alcoholic fatty liver disease via the SHMT2/glycine/mTOR/PPAR-γ signaling pathway.
Guo F, Xiong H, Tsao R, Wen X, Liu J, Chen D, Jiang L, Sun Y
Food & function 2023 Jul 31;14(15):7195-7208
Food & function 2023 Jul 31;14(15):7195-7208
Sulforaphane protects microvascular endothelial cells in lower limb ischemia/reperfusion injury mice.
Chen F, Zhan J, Al Mamun A, Tao Y, Huang S, Zhao J, Zhang Y, Xu Y, Du S, Lu W, Li X, Chen Z, Xiao J
Food & function 2023 Jul 31;14(15):7176-7194
Food & function 2023 Jul 31;14(15):7176-7194
Flavinated SDHA Underlies the Change in Intrinsic Optical Properties of Oral Cancers.
Marumo T, Maduka CV, Ural E, Apu EH, Chung SJ, van den Berg NS, Zhou Q, Martin BA, Rosenthal EL, Shibahara T, Contag CH
bioRxiv : the preprint server for biology 2023 Jul 31;
bioRxiv : the preprint server for biology 2023 Jul 31;
TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.
Ye M, Hu Y, Zhao B, Mou Q, Ni Y, Luo J, Li L, Zhang H, Zhao Y
Investigative ophthalmology & visual science 2023 Jul 3;64(10):1
Investigative ophthalmology & visual science 2023 Jul 3;64(10):1
Silencing of UTX Mitigates Aging-Associated Cardiac Fibrosis via Blocking Cardiac Fibroblasts-to-Myofibroblasts Trans-Differentiation.
Li C, Lin T, Li D, Si D, Sun H, Yang S, Zhang Z, Zhang Q, Shi K
Anatolian journal of cardiology 2023 Jul 3;27(7):398-407
Anatolian journal of cardiology 2023 Jul 3;27(7):398-407
A simple and available measurement of onco-sEV dsDNA to protein ratio as a potential tumor marker.
Sun Y, Li M, Zhang X, Xu D, Wu J, Gu X, Khan A, Shen H, Li Z
BMC cancer 2023 Jul 3;23(1):614
BMC cancer 2023 Jul 3;23(1):614
Astaxanthin alleviates lipopolysaccharide-induced acute lung injury by suppressing ferroptosis.
Dong X, Li D, Fang Z, Zhang C, Wang J, Wan X
Food & function 2023 Jul 3;14(13):6115-6127
Food & function 2023 Jul 3;14(13):6115-6127
TLR4 Overexpression Aggravates Bacterial Lipopolysaccharide-Induced Apoptosis via Excessive Autophagy and NF-κB/MAPK Signaling in Transgenic Mammal Models.
Wang S, Zhang K, Song X, Huang Q, Lin S, Deng S, Qi M, Yang Y, Lu Q, Zhao D, Meng F, Li J, Lian Z, Luo C, Yao Y
Cells 2023 Jul 3;12(13)
Cells 2023 Jul 3;12(13)
NPC1-dependent alterations in K(V)2.1-Ca(V)1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease.
Casas M, Murray KD, Hino K, Vierra NC, Simó S, Trimmer JS, Dixon RE, Dickson EJ
Nature communications 2023 Jul 28;14(1):4553
Nature communications 2023 Jul 28;14(1):4553
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Bai Y, Zhang L, Zheng B, Zhang X, Zhang H, Zhao A, Yu J, Yang Z, Wen J
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
DNA framework-engineered chimeras platform enables selectively targeted protein degradation.
Zhou L, Yu B, Gao M, Chen R, Li Z, Gu Y, Bian J, Ma Y
Nature communications 2023 Jul 27;14(1):4510
Nature communications 2023 Jul 27;14(1):4510
The pharmacological mechanism of β-elemene in the treatment of esophageal cancer revealed by network pharmacology and experimental verification.
Zhou D, Wu X, Liu X, He S, Ni J, Chen B, Mu D
Scientific reports 2023 Jul 27;13(1):12160
Scientific reports 2023 Jul 27;13(1):12160
Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.
Lin XT, Zhang J, Liu ZY, Wu D, Fang L, Li CM, Yu HQ, Xie CM
Cell reports 2023 Jul 25;42(7):112812
Cell reports 2023 Jul 25;42(7):112812
NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer.
Wei W, Zhang S, Han H, Wang X, Zheng S, Wang Z, Yang C, Wang L, Ma J, Guo S, Wang J, Liu L, Choe J, Lin S
Cell reports 2023 Jul 25;42(7):112810
Cell reports 2023 Jul 25;42(7):112810
Mixed-Lineage Leukemia 1 Inhibition Enhances the Differentiation Potential of Bovine Embryonic Stem Cells by Increasing H3K4 Mono-Methylation at Active Promoters.
Li C, Han X, Wang J, Liu F, Zhang Y, Li Z, Lu Z, Yue Y, Xiang J, Li X
International journal of molecular sciences 2023 Jul 25;24(15)
International journal of molecular sciences 2023 Jul 25;24(15)
Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.
Yazar V, Kühlwein JK, Knehr A, Grozdanov V, Ekici AB, Ludolph AC, Danzer KM
Scientific reports 2023 Jul 25;13(1):12019
Scientific reports 2023 Jul 25;13(1):12019
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Wen RJ, Dong X, Zhuang HW, Pang FX, Ding SC, Li N, Mai YX, Zhou ST, Wang JY, Zhang JF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154881
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154881
Fufang Shenhua tablet inhibits renal fibrosis by inhibiting PI3K/AKT.
Li R, Shi C, Wei C, Wang C, Du H, Liu R, Wang X, Hong Q, Chen X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154873
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154873
Luteolin inhibits subretinal fibrosis and epithelial-mesenchymal transition in laser-induced mouse model via suppression of Smad2/3 and YAP signaling.
Zhang C, Zhang Y, Hu X, Zhao Z, Chen Z, Wang X, Zhang Z, Jin H, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154865
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154865
Hypoxia-based classification and prognostic signature for clinical management of hepatocellular carcinoma.
Li K, Yang Y, Ma M, Lu S, Li J
World journal of surgical oncology 2023 Jul 22;21(1):216
World journal of surgical oncology 2023 Jul 22;21(1):216
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
Zhang Z, Cui S, Fu Y, Wang J, Liu J, Wei F
Cellular & molecular biology letters 2023 Jul 21;28(1):57
Cellular & molecular biology letters 2023 Jul 21;28(1):57
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Liu J, Cao C, Jin Y, Wang Y, Ma X, Li J, Guo S, Yang J, Niu J, Liang X
iScience 2023 Jul 21;26(7):107022
iScience 2023 Jul 21;26(7):107022
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
Chen C, Ren A, Yi Q, Cai J, Khan M, Lin Y, Huang Z, Lin J, Zhang J, Liu W, Xu A, Tian Y, Yuan Y, Zheng R
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, Tan B, Chen Z, Shen C, Gao L, Small A, Wang K, Leung K, Zhang Z, Qin X, Deng X, Xia Q, Su R, Chen J
Cell 2023 Jul 20;186(15):3208-3226.e27
Cell 2023 Jul 20;186(15):3208-3226.e27
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.
Wang X, Dong FL, Wang YQ, Wei HL, Li T, Li J
Cell death & disease 2023 Jul 20;14(7):451
Cell death & disease 2023 Jul 20;14(7):451
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
bioRxiv : the preprint server for biology 2023 Jul 20;
bioRxiv : the preprint server for biology 2023 Jul 20;
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Yang S, Sun Y, Long M, Zhou X, Yuan M, Yang L, Luo W, Cheng Y, Zhang X, Jiang W, Chao J
Particle and fibre toxicology 2023 Jul 19;20(1):29
Particle and fibre toxicology 2023 Jul 19;20(1):29
Cold exposure protects against medial arterial calcification development via autophagy.
Li FX, Liu JJ, Xu F, Shan SK, Zheng MH, Lei LM, Lin X, Guo B, Li CC, Wu F, Tang KX, Cao YC, Wu YY, Duan JY, Wu YL, He SY, Chen X, Yuan LQ
Journal of nanobiotechnology 2023 Jul 17;21(1):226
Journal of nanobiotechnology 2023 Jul 17;21(1):226
PPARα is involved in high-fat diet-induced risk avoidance impairment via the regulation of hippocampal BDNF.
Zhu XY, Luo J, Wei XJ, Pan LH, Xu XF, Hu LB, Dong YB, Jiang YK, Dong FY, Xu L, Xu LM, Liu AM, Zhang XQ
Food & function 2023 Jul 17;14(14):6541-6553
Food & function 2023 Jul 17;14(14):6541-6553
Target Discovery of Matrine against PRRSV in Marc-145 Cells via Activity-Based Protein Profiling.
Ling X, Cao Z, Sun P, Zhang H, Sun Y, Zhong J, Yin W, Fan K, Zheng X, Li H, Sun N
International journal of molecular sciences 2023 Jul 16;24(14)
International journal of molecular sciences 2023 Jul 16;24(14)
A comparative study of the neuroprotective effects of dl-3-n-butylphthalide and edaravone dexborneol on cerebral ischemic stroke rats.
Zhang H, Wang L, Zhu B, Yang Y, Cai C, Wang X, Deng L, He B, Cui Y, Zhou W
European journal of pharmacology 2023 Jul 15;951:175801
European journal of pharmacology 2023 Jul 15;951:175801
Resveratrol inhibits autophagy against myocardial ischemia-reperfusion injury through the DJ-1/MEKK1/JNK pathway.
Liu S, Ren J, Liu S, Zhao X, Liu H, Zhou T, Wang X, Liu H, Tang L, Chen H
European journal of pharmacology 2023 Jul 15;951:175748
European journal of pharmacology 2023 Jul 15;951:175748
Recombinant human neuregulin-1 alleviates immobilization-induced neuromuscular dysfunction via neuregulin-1/ErbB signaling pathway in rat.
Yang J, Cao J, Min S, Li P, Lv F, Ren L
Archives of biochemistry and biophysics 2023 Jul 15;743:109631
Archives of biochemistry and biophysics 2023 Jul 15;743:109631
Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.
Xu W, Yuan Y, Tian Y, Cheng C, Chen Y, Zeng L, Yuan Y, Li D, Zheng L, Luo T
Journal of hazardous materials 2023 Jul 15;454:131470
Journal of hazardous materials 2023 Jul 15;454:131470
Antidepressant effects of repeated s-ketamine administration as NMDAR Antagonist: Involvement of CaMKIIα and mTOR signaling in the hippocampus of CUMS mice.
Liu B, Du Y, Xu C, Liu Q, Zhang L
Brain research 2023 Jul 15;1811:148375
Brain research 2023 Jul 15;1811:148375
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation.
Du J, Liu Y, Lan G, Zhou Y, Ni Y, Liao K, Zheng F, Cheng Q, Shi G, Su X
Cell death & disease 2023 Jul 15;14(7):432
Cell death & disease 2023 Jul 15;14(7):432
A novel cuproptosis-related diagnostic gene signature and differential expression validation in atherosclerosis.
Cui Y, Chen Y, Gan N, Li M, Liao W, Zhou Y, Xiang Q, Gong X, Guo Q, Hu P, Zheng XL, Shang D, Peng J, Tang Z
Molecular biomedicine 2023 Jul 14;4(1):21
Molecular biomedicine 2023 Jul 14;4(1):21
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
Qi M, Zhong H, Cheng Z, Chen S, Xiao H, Shang J, Chen L, Sun J
Journal of medicinal chemistry 2023 Jul 13;66(13):9184-9200
Journal of medicinal chemistry 2023 Jul 13;66(13):9184-9200
ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis.
Yang Z, Zou S, Zhang Y, Zhang J, Zhang P, Xiao L, Xie Y, Meng M, Feng J, Kang L, Lee MH, Fang L
Nature communications 2023 Jul 13;14(1):4193
Nature communications 2023 Jul 13;14(1):4193
Sodium Butyrate Ameliorates Deoxynivalenol-Induced Oxidative Stress and Inflammation in the Porcine Liver via NR4A2-Mediated Histone Acetylation.
Zong Q, Li K, Qu H, Hu P, Xu C, Wang H, Wu S, Wang S, Liu HY, Cai D, Bao W
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10427-10437
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10427-10437
Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability.
Zhang X, Yu Q, Wu Y, Zhang Y, He Y, Wang R, Yu X, Li S
Cell discovery 2023 Jul 11;9(1):71
Cell discovery 2023 Jul 11;9(1):71
USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis.
Liu S, Xiang Y, Wang B, Gao C, Chen Z, Xie S, Wu J, Liu Y, Zhao X, Yang C, Yue Z, Wang L, Wen X, Zhang R, Zhang F, Xu H, Zhai X, Zheng H, Zhang H, Qian M
Blood advances 2023 Jul 11;7(13):3099-3112
Blood advances 2023 Jul 11;7(13):3099-3112
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer's disease.
Zhang S, Cao F, Li W, Abumaria N
Science signaling 2023 Jul 11;16(793):eade6325
Science signaling 2023 Jul 11;16(793):eade6325
Hedgehog signaling is a potential therapeutic target for vascular calcification.
Huang A, Li L, Liu X, Lian Q, Guo G, Xu T, Lu X, Ma L, Ma H, Yu Y, Yao L
Gene 2023 Jul 1;872:147457
Gene 2023 Jul 1;872:147457
Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation to drive HCC.
Yu HQ, Li F, Xiong H, Fang L, Zhang J, Bie P, Xie CM
Hepatology communications 2023 Jul 1;7(7)
Hepatology communications 2023 Jul 1;7(7)
ATAXIA TELANGIECTASIA MUTATED PROTECTS AGAINST LIPOPOLYSACCARIDE-INDUCED BLOOD-BRAIN BARRIER DISRUPTION BY REGULATING ATK/DRP1-MEDIATED MITOCHONDRIAL HOMEOSTASIS.
Luo S, Lyu Z, Ge L, Li Y, Liu Y, Yuan Y, Zhao R, Huang L, Zhao J, Huang H, Luo Y
Shock (Augusta, Ga.) 2023 Jul 1;60(1):100-109
Shock (Augusta, Ga.) 2023 Jul 1;60(1):100-109
NF-κB pathway affects silica nanoparticle-induced fibrosis via inhibited inflammatory response and epithelial-mesenchymal transition in 3D co-culture.
Yang X, Zhang J, Xiong M, Yang Y, Yang P, Li N, Shi F, Zhu Y, Guo K, Jin Y
Toxicology letters 2023 Jul 1;383:141-151
Toxicology letters 2023 Jul 1;383:141-151
A high-fat diet increases hepatic mitochondrial turnover through restricted acetylation in a NAFLD mouse model.
Aghayev M, Arias-Alvarado A, Ilchenko S, Lepp J, Scott I, Chen YR, Zhang GF, Tsai TH, Kasumov T
American journal of physiology. Endocrinology and metabolism 2023 Jul 1;325(1):E83-E98
American journal of physiology. Endocrinology and metabolism 2023 Jul 1;325(1):E83-E98
Implications of ferroptosis in silver nanoparticle-induced cytotoxicity of macrophages.
Zheng G, Zhang J, Zhang X, Zhang Z, Liu S, Zhang S, Zhang C
Ecotoxicology and environmental safety 2023 Jul 1;259:115057
Ecotoxicology and environmental safety 2023 Jul 1;259:115057
Cataract-causing variant Q70P damages structural stability of βB1-crystallin and increases its tendency to form insoluble aggregates.
Zhang Y, Ren L, Wu W, Liu J, Tian Q, Yao K, Yu Y, Hu L, Chen X
International journal of biological macromolecules 2023 Jul 1;242(Pt 2):124722
International journal of biological macromolecules 2023 Jul 1;242(Pt 2):124722
Xanthine oxidase, a therapeutic target of realgar for non-small cell lung cancer.
Guo R, Gong X, Li K, Qiu Z, Yang L, Wan Y, Yao X, Long C, Xu J, Li K, Liu J, Liu J
Heliyon 2023 Jan;9(1):e12666
Heliyon 2023 Jan;9(1):e12666
Interleukin-19 upregulates fibronectin and collagen I expression via the NF-κB-Smad2/3 pathway in fibroblasts of patients with chronic rhinosinusitis.
Bao H, Li X, Lai X, Chen X, Li Y, Yao Z, Huang Z, Huang J, Chang L, Zhang G
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jan;72(1):43-55
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jan;72(1):43-55
CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau.
Polanco JC, Akimov Y, Fernandes A, Briner A, Hand GR, van Roijen M, Balistreri G, Götz J
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Al-Raimi HAI, Kong J, Ran Y, Zhu L, Li J, Liu X, Yang X, Qi D, Liu T
Archives of medical research 2023 Jan;54(1):27-36
Archives of medical research 2023 Jan;54(1):27-36
The expression and significance of long non-coding RNA ITGB2-AS1 in renal clear cell carcinoma.
Zhou W, Liu ZG, Wang LQ
Saudi medical journal 2023 Jan;44(1):19-28
Saudi medical journal 2023 Jan;44(1):19-28
IL-6/Stat3 suppresses osteogenic differentiation in ossification of the posterior longitudinal ligament via miR-135b-mediated BMPER reduction.
Ji N, Yu Z
Cell and tissue research 2023 Jan;391(1):145-157
Cell and tissue research 2023 Jan;391(1):145-157
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
Xu X, Feng Y, Han C, Yao Z, Liu Y, Luo C, Sheng J
Environmental toxicology 2023 Jan;38(1):205-215
Environmental toxicology 2023 Jan;38(1):205-215
Silencing circUSP48 suppresses osteosarcoma progression by regulating the miR-335/ smad nuclear interacting protein 1 pathway.
Luo Y, Yang B, Yuan X, Zheng J
Journal of clinical laboratory analysis 2023 Jan;37(2):e24828
Journal of clinical laboratory analysis 2023 Jan;37(2):e24828
Quercetin inhibits the amphiregulin/EGFR signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in obstructive nephropathy.
Wang Q, Wang F, Li X, Ma Z, Jiang D
Phytotherapy research : PTR 2023 Jan;37(1):111-123
Phytotherapy research : PTR 2023 Jan;37(1):111-123
Pathological implication of CaMKII in NF-κB pathway and SASP during cardiomyocytes senescence.
Li T, Meng Y, Ding P, Wang H, Liu J, Xia C, Chen Y, Li J
Mechanisms of ageing and development 2023 Jan;209:111758
Mechanisms of ageing and development 2023 Jan;209:111758
Targeting 7-dehydrocholesterol reductase against EV-A71 replication by upregulating interferon response.
Wang H, Cui B, Yan H, Wu S, Wang K, Yang G, Jiang J, Li Y
Antiviral research 2023 Jan;209:105497
Antiviral research 2023 Jan;209:105497
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Li M, Zhang Y, Han T, Guan L, Fan D, Wu Q, Liu J, Xu Y, Fan Y
Phytochemistry 2023 Jan;205:113487
Phytochemistry 2023 Jan;205:113487
Translational control of murine adiponectin expression by an upstream open reading frame element.
Vasu K, Ramachandiran I, Chechi A, Khan K, Khan D, Kaufman R, Fox PL
RNA biology 2023 Jan;20(1):737-749
RNA biology 2023 Jan;20(1):737-749
Eugenol attenuates ischemia-mediated oxidative stress in cardiomyocytes via acetylation of histone at H3K27.
Randhawa PK, Rajakumar A, Futuro de Lima IB, Gupta MK
Free radical biology & medicine 2023 Jan;194:326-336
Free radical biology & medicine 2023 Jan;194:326-336
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Liu D, Li X, Zeng B, Zhao Q, Chen H, Zhang Y, Chen Y, Wang J, Xing HR
Stem cell reviews and reports 2023 Jan;19(1):155-169
Stem cell reviews and reports 2023 Jan;19(1):155-169
Extracellular magnetic labeling of biomimetic hydrogel-induced human mesenchymal stem cell spheroids with ferumoxytol for MRI tracking.
Yan S, Hu K, Zhang M, Sheng J, Xu X, Tang S, Li Y, Yang S, Si G, Mao Y, Zhang Y, Zhang F, Gu N
Bioactive materials 2023 Jan;19:418-428
Bioactive materials 2023 Jan;19:418-428
BRD4 inhibitor suppresses melanoma metastasis via the SPINK6/EGFR-EphA2 pathway.
Hu R, Li Y, Guo Y, Li X, Du S, Liao M, Hou H, Sun H, Zhao S, Su J, Chen X, Yin M
Pharmacological research 2023 Jan;187:106609
Pharmacological research 2023 Jan;187:106609
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Tong F, Zhao JX, Fang ZY, Cui XT, Su DY, Liu X, Zhou JH, Wang GX, Qiu ZJ, Liu SZ, Fu JQ, Kang CS, Wang JC, Wang QX
Pharmacological research 2023 Jan;187:106606
Pharmacological research 2023 Jan;187:106606
Transforming growth factor-β1 promotes early odontoblastic differentiation of dental pulp stem cells via activating AKT, Erk1/2 and p38 MAPK pathways.
Bai Y, Cheng X, Liu X, Guo Q, Wang Z, Fu Y, He W, Yu Q
Journal of dental sciences 2023 Jan;18(1):87-94
Journal of dental sciences 2023 Jan;18(1):87-94
Circ_0004491 stimulates guanine nucleotide-binding protein alpha subunit to inhibit the malignant progression of oral squamous cell carcinoma by sponging miR-2278.
Cheng T, Huang F, Zhang Y, Zhou Z
Journal of dental sciences 2023 Jan;18(1):237-247
Journal of dental sciences 2023 Jan;18(1):237-247
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Mi Y, Wei C, Sun L, Liu H, Zhang J, Luo J, Yu X, He J, Ge H, Liu P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Pyruvate dehydrogenase kinase 4 promotes osteoblastic potential of BMP9 by boosting Wnt/β-catenin signaling in mesenchymal stem cells.
Yang YY, Luo HH, Deng YX, Yao XT, Zhang J, Su YX, He BC
The international journal of biochemistry & cell biology 2023 Jan;154:106341
The international journal of biochemistry & cell biology 2023 Jan;154:106341
Diagnostic, prognostic, and immunological roles of CD177 in cervical cancer.
Liao W, Li W, Li Y, Liu T, Wang Y, Feng D, Shen F
Journal of cancer research and clinical oncology 2023 Jan;149(1):173-189
Journal of cancer research and clinical oncology 2023 Jan;149(1):173-189
Parasympathetic-macrophages-ductal epithelial cells axis promotes female rat submandibular gland regeneration after excretory duct ligation/deligation.
Wang B, Li D, Li J, An W, Li Z, Shao Q, Qin L
Archives of oral biology 2023 Jan;145:105586
Archives of oral biology 2023 Jan;145:105586
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Hui Y, Xu Z, Li J, Kuang L, Zhong Y, Tang Y, Wei J, Zhou H, Zheng T
Metabolism: clinical and experimental 2023 Jan;138:155340
Metabolism: clinical and experimental 2023 Jan;138:155340
Co-Polymer Carrier with Dual Advantages of Cartilage-Penetrating and Targeting Improves Delivery and Efficacy of MicroRNA Treatment of Osteoarthritis.
Zhao Y, Deng X, Tan S, Zhang J, Han J, Wang X, Pei J, Li H, Deng X, Yin C, Yin D, Tian Y, Qian A
Advanced healthcare materials 2023 Jan;12(6):e2202143
Advanced healthcare materials 2023 Jan;12(6):e2202143
Development and validation of a leukocyte-associated immunoglobulin-like receptor-1 prognostic signature for lower-grade gliomas.
Fang Z, Lin L, Tu Z, Zhu X, Li J, Luo P, Huang K, Wu L
Cancer medicine 2023 Jan;12(1):712-732
Cancer medicine 2023 Jan;12(1):712-732
Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury.
Hu Z, Xuan L, Wu T, Jiang N, Liu X, Chang J, Wang T, Han N, Tian X
International immunopharmacology 2023 Jan;114:109616
International immunopharmacology 2023 Jan;114:109616
Amelioration of central neurodegeneration by docosahexaenoic acid in trigeminal neuralgia rats through the regulation of central neuroinflammation.
Mu G, Ren C, Zhang Y, Lu B, Feng J, Wu D, Xu X, Ou C
International immunopharmacology 2023 Jan;114:109544
International immunopharmacology 2023 Jan;114:109544
Huc-MSCs-derived exosomes attenuate neuropathic pain by inhibiting activation of the TLR2/MyD88/NF-κB signaling pathway in the spinal microglia by targeting Rsad2.
Gao X, Gao LF, Zhang YN, Kong XQ, Jia S, Meng CY
International immunopharmacology 2023 Jan;114:109505
International immunopharmacology 2023 Jan;114:109505
Halofuginone ameliorates systemic lupus erythematosus by targeting Blk in myeloid-derived suppressor cells.
Ni J, Li X, Tu X, Zhu H, Wang S, Hou Y, Dou H
International immunopharmacology 2023 Jan;114:109487
International immunopharmacology 2023 Jan;114:109487
Effective-compounds of Jinshui Huanxian formula ameliorates fibroblast activation in pulmonary fibrosis by inhibiting the activation of mTOR signaling.
Li J, Li K, Tian Y, Zhao P, Liu X, Li M, Bai Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154604
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154604
Shikonin triggers GSDME-mediated pyroptosis in tumours by regulating autophagy via the ROS-MAPK14/p38α axis.
Ju X, Zhang H, Wang J, Sun Z, Guo L, Wang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154596
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154596
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Zhang Q, Ren J, Wang F, Li M, Pan M, Zhang H, Qu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Neuronal differentiation drives the antitumor activity of mitogen-activated protein kinase kinase (MEK) inhibition in glioblastoma.
Khan S, Martinez-Ledesma E, Dong J, Mahalingam R, Park SY, Piao Y, Koul D, Balasubramaniyan V, de Groot JF, Yung WKA
Neuro-oncology advances 2023 Jan-Dec;5(1):vdad132
Neuro-oncology advances 2023 Jan-Dec;5(1):vdad132
Treatment with paraquat affects the expression of ferroptosis-related genes.
Ge X, Cai Q, Zhang S, Wu X, Ying P, Ke J, Yang Z
Human & experimental toxicology 2023 Jan-Dec;42:9603271231167585
Human & experimental toxicology 2023 Jan-Dec;42:9603271231167585
Immunopotentiation effects of apigenin on NK cell proliferation and killing pancreatic cancer cells.
Feng YB, Chen L, Chen FX, Yang Y, Chen GH, Zhou ZH, Xu CF
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231161174
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231161174
1,25-Dihydroxyvitamin D3: A Positive Factor for the Osteogenic Differentiation of hPDLSCs and for the Tissue Regenerative Activity of Cell Sheets.
Wang J, Guo S, Xu X, Zhang C
Cell transplantation 2023 Jan-Dec;32:9636897231202541
Cell transplantation 2023 Jan-Dec;32:9636897231202541
SUV39H1 Inhibits Angiogenesis in Limb Ischemia of Mice.
Niu W, Cao W, Wu F, Liang C
Cell transplantation 2023 Jan-Dec;32:9636897231198167
Cell transplantation 2023 Jan-Dec;32:9636897231198167
Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis.
Li H, Ren J, Cui H, Wang D, Zhao R, Liu X, Tian S, Wang J, Zhang J, Li P, Thorne RF, Duan S
Cell transplantation 2023 Jan-Dec;32:9636897231177356
Cell transplantation 2023 Jan-Dec;32:9636897231177356
Elevated Angiotensin-II Levels Contribute to the Pathogenesis of Open-Angle Glaucoma Via Inducing the Expression of Fibrosis-Related Genes in Trabecular Meshwork Cells Through a ROS/NOX4/SMAD3 Axis.
Li H, Cui H, Ren J, Wang D, Zhao R, Zhu S, Liu S, Liu X, Tian S, Zhang Y, Zhao P, Li P, Thorne RF, Duan S
Cell transplantation 2023 Jan-Dec;32:9636897231162526
Cell transplantation 2023 Jan-Dec;32:9636897231162526
Hypermethylation-Mediated lncRNA MAGI2-AS3 Downregulation Facilitates Malignant Progression of Laryngeal Squamous Cell Carcinoma via Interacting With SPT6.
Wang J, Yang C, Cao H, Yang J, Meng W, Yu M, Yu L, Wang B
Cell transplantation 2023 Jan-Dec;32:9636897231154574
Cell transplantation 2023 Jan-Dec;32:9636897231154574
DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer.
Hou Y, Liu J, Huang S, Wang L, Hu J, Liu X
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231167249
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231167249
Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1.
Liu Y, She W, Li Y, Wang M, Liu Y, Ning B, Xu T, Huang T, Wei Y
Journal of translational medicine 2023 Jan 7;21(1):7
Journal of translational medicine 2023 Jan 7;21(1):7
Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization.
Zhang H, Chen Y, Li F, Wu C, Cai W, Ye H, Su H, He M, Yang L, Wang X, Zhou K, Ni W
Journal of neuroinflammation 2023 Jan 7;20(1):6
Journal of neuroinflammation 2023 Jan 7;20(1):6
PAK1 Is Involved in the Spindle Assembly during the First Meiotic Division in Porcine Oocytes.
Peng L, He Y, Wang W, Chu Y, Lin Q, Rui R, Li Q, Ju S
International journal of molecular sciences 2023 Jan 6;24(2)
International journal of molecular sciences 2023 Jan 6;24(2)
A distal super-enhancer activates oncogenic ETS2 via recruiting MECOM in inflammatory bowel disease and colorectal cancer.
Chen Y, Ying Y, Wang M, Ma C, Jia M, Shi L, Wang S, Zheng X, Chen W, Shu XS
Cell death & disease 2023 Jan 6;14(1):8
Cell death & disease 2023 Jan 6;14(1):8
Impact of Hypermannosylation on the Structure and Functionality of the ER and the Golgi Complex.
Franzka P, Schüler SC, Kentache T, Storm R, Bock A, Katona I, Weis J, Buder K, Kaether C, Hübner CA
Biomedicines 2023 Jan 6;11(1)
Biomedicines 2023 Jan 6;11(1)
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Wei P, Lin D, Zhang M, Luo C, Wu X, Deng B, Cui K, Chen Z
European journal of pharmacology 2023 Jan 5;938:175434
European journal of pharmacology 2023 Jan 5;938:175434
Co-delivery of ibrutinib and hydroxychloroquine by albumin nanoparticles for enhanced chemotherapy of glioma.
Yang Z, Du Y, Lei L, Xia X, Wang X, Tong F, Li Y, Gao H
International journal of pharmaceutics 2023 Jan 5;630:122436
International journal of pharmaceutics 2023 Jan 5;630:122436
Human zygotic genome activation is initiated from paternal genome.
Yuan S, Zhan J, Zhang J, Liu Z, Hou Z, Zhang C, Yi L, Gao L, Zhao H, Chen ZJ, Liu J, Wu K
Cell discovery 2023 Jan 31;9(1):13
Cell discovery 2023 Jan 31;9(1):13
TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis.
Liu H, Liu Y, Jin SG, Johnson J, Xuan H, Lu D, Li J, Zhai L, Li X, Zhao Y, Liu M, Craig SEL, Floramo JS, Molchanov V, Li J, Li JD, Krawczyk C, Shi X, Pfeifer GP, Yang T
Cell reports 2023 Jan 31;42(1):112012
Cell reports 2023 Jan 31;42(1):112012
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cheng L, He Q, Liu B, Chen L, Lv F, Li X, Li Y, Liu C, Song Y, Xing Y
Cell death & disease 2023 Jan 31;14(1):74
Cell death & disease 2023 Jan 31;14(1):74
Development and validation of an inflammatory response-related prognostic model and immune infiltration analysis in glioblastoma.
Zhu W, Luo N, Li Q, Chen X, Li X, Fu M, Yang F, Chen Z, Zhang Y, Zhang Y, Peng X, Hu G
Annals of translational medicine 2023 Jan 31;11(2):69
Annals of translational medicine 2023 Jan 31;11(2):69
Network and experimental pharmacology on mechanism of Si-Wu-tang improving ovarian function in a mouse model of premature ovarian failure induced by cyclophosphamide.
Liu X, Song Y, Zhou F, Zhang C, Li F, Hu R, Ma W, Song K, Tang Z, Zhang M
Journal of ethnopharmacology 2023 Jan 30;301:115842
Journal of ethnopharmacology 2023 Jan 30;301:115842
Fufang-zhenzhu-tiaozhi formula protects islet against injury and promotes β cell regeneration in diabetic mice.
Chen X, Yin J, Zhong Q, Wang K, Zhang X, Liang M, Lin Q, Wang H, Wang W, Wang L, Hu X, Bei W, Guo J
Journal of ethnopharmacology 2023 Jan 30;301:115791
Journal of ethnopharmacology 2023 Jan 30;301:115791
Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis.
Ai G, Huang R, Xie J, Zhong L, Wu X, Qin Z, Su Z, Chen J, Yang X, Dou Y
Journal of ethnopharmacology 2023 Jan 30;301:115775
Journal of ethnopharmacology 2023 Jan 30;301:115775
Nanoparticulate MgH(2) ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
Li Z, Chen K, Shao Q, Lu H, Zhang X, Pu Y, Sun X, He H, Cao L
Journal of neuroinflammation 2023 Jan 30;20(1):16
Journal of neuroinflammation 2023 Jan 30;20(1):16
Matrine combined with Osthole inhibited the PERK apoptosis of splenic lymphocytes in PCV2-infected mice model.
Xu Y, Wan S, Sun P, Khan A, Guo J, Zheng X, Sun Y, Fan K, Yin W, Li H, Sun N
BMC veterinary research 2023 Jan 30;19(1):26
BMC veterinary research 2023 Jan 30;19(1):26
Protective effects of Lycium barbarum L. berry extracts against oxidative stress-induced damage of the retina of aging mouse and ARPE-19 cells.
Zheng HL, Li MT, Zhou T, Wang YY, Shang EX, Hua YQ, Duan JA, Zhu Y
Food & function 2023 Jan 3;14(1):399-412
Food & function 2023 Jan 3;14(1):399-412
Dietary leucine and fish oil cooperatively regulate skeletal myofiber type transformation via the CaMKII signaling pathway of pigs.
Gong S, Yin Y, Han M, Guo L, Duan Y, Guo Q, Yin J, Li F
Food & function 2023 Jan 3;14(1):133-147
Food & function 2023 Jan 3;14(1):133-147
Goat FADS2 controlling fatty acid metabolism is directly regulated by SREBP1 in mammary epithelial cells.
Wu J, Luo J, Xia Y, An X, Guo P, He Q, Tian H, Hu Q, Li C, Wang H
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Activation of autophagy inhibits the activation of NLRP3 inflammasome and alleviates sevoflurane-induced cognitive dysfunction in elderly rats.
Zhou J, Zhang C, Fang X, Zhang N, Zhang X, Zhu Z
BMC neuroscience 2023 Jan 28;24(1):9
BMC neuroscience 2023 Jan 28;24(1):9
Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction.
Lin H, Lin J, Pan T, Li T, Jiang H, Fang Y, Wang Y, Wu F, Huang J, Zhang H, Chen D, Chen Y
Cell death & disease 2023 Jan 28;14(1):68
Cell death & disease 2023 Jan 28;14(1):68
Anti-inflammatory and Chondroprotective Effects of Platelet-derived Growth Factor-BB on Osteoarthritis Rat Models.
Cai Y, Wang Z, Liao B, Sun Z, Zhu P
The journals of gerontology. Series A, Biological sciences and medical sciences 2023 Jan 26;78(1):51-59
The journals of gerontology. Series A, Biological sciences and medical sciences 2023 Jan 26;78(1):51-59
Naringenin Ameliorates Hyperuricemia by Regulating Renal Uric Acid Excretion via the PI3K/AKT Signaling Pathway and Renal Inflammation through the NF-κB Signaling Pathway.
Yang B, Xin M, Liang S, Huang Y, Li J, Wang C, Liu C, Song X, Sun J, Sun W
Journal of agricultural and food chemistry 2023 Jan 25;71(3):1434-1446
Journal of agricultural and food chemistry 2023 Jan 25;71(3):1434-1446
Master mitotic kinases regulate viral genome delivery during papillomavirus cell entry.
Rizzato M, Mao F, Chardon F, Lai KY, Villalonga-Planells R, Drexler HCA, Pesenti ME, Fiskin M, Roos N, King KM, Li S, Gamez ER, Greune L, Dersch P, Simon C, Masson M, Van Doorslaer K, Campos SK, Schelhaas M
Nature communications 2023 Jan 23;14(1):355
Nature communications 2023 Jan 23;14(1):355
Microglial activation and over pruning involved in developmental epilepsy.
Wu Q, Wang H, Liu X, Zhao Y, Su P
Journal of neuropathology and experimental neurology 2023 Jan 20;82(2):150-159
Journal of neuropathology and experimental neurology 2023 Jan 20;82(2):150-159
Inhibition of fibroblast activation protein ameliorates cartilage matrix degradation and osteoarthritis progression.
Fan A, Wu G, Wang J, Lu L, Wang J, Wei H, Sun Y, Xu Y, Mo C, Zhang X, Pang Z, Pan Z, Wang Y, Lu L, Fu G, Ma M, Zhu Q, Cao D, Qin J, Yin F, Yue R
Bone research 2023 Jan 2;11(1):3
Bone research 2023 Jan 2;11(1):3
USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.
Zhao J, Bai J, Peng F, Qiu C, Li Y, Zhong L
Cell death & disease 2023 Jan 19;14(1):40
Cell death & disease 2023 Jan 19;14(1):40
LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway.
Jiang Y, Xu CH, Zhao Y, Ji YH, Wang XT, Liu Y
European journal of histochemistry : EJH 2023 Jan 16;67(1)
European journal of histochemistry : EJH 2023 Jan 16;67(1)
Comparison of DNA targeting CRISPR editors in human cells.
Huang H, Lv W, Li J, Huang G, Tan Z, Hu Y, Ma S, Zhang X, Huang L, Lin Y
Cell & bioscience 2023 Jan 16;13(1):11
Cell & bioscience 2023 Jan 16;13(1):11
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
Wu Y, Wu Y, Yu J, Zhang Y, Li Y, Fu R, Sun Y, Zhao K, Xiao Q
European journal of pharmacology 2023 Jan 15;939:175476
European journal of pharmacology 2023 Jan 15;939:175476
Gardenoside ameliorates inflammation and inhibits ECM degradation in IL-1β-treated rat chondrocytes via suppressing NF-κB signaling pathways.
Xia T, Zhao R, He S, Wang L, Fu X, Zhao Y, Qiao S, An J
Biochemical and biophysical research communications 2023 Jan 15;640:164-172
Biochemical and biophysical research communications 2023 Jan 15;640:164-172
MiR-652-3p promotes malignancy and metastasis of cancer cells via inhibiting TNRC6A in hepatocellular carcinoma.
Chen W, Ru J, Wu T, Man D, Wu J, Wu L, Sun Y, Yu H, Li M, Zhang G, Zhu X, Tong R, Xiao H, Li Y, Yang B
Biochemical and biophysical research communications 2023 Jan 15;640:1-11
Biochemical and biophysical research communications 2023 Jan 15;640:1-11
Genetic screening of MMP1 as a potential pathogenic gene in chronic obstructive pulmonary disease.
Yi E, Cao W, Zhang J, Lin B, Wang Z, Wang X, Bai G, Mei X, Xie C, Jin J, Liu X, Li H, Wu F, Lin Z, Sun R, Li B, Zhou Y, Ran P
Life sciences 2023 Jan 15;313:121214
Life sciences 2023 Jan 15;313:121214
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Zhang J, Tang Y, Hu Z, Xu W, Ma Y, Xu P, Xing H, Niu Q
Ecotoxicology and environmental safety 2023 Jan 15;250:114511
Ecotoxicology and environmental safety 2023 Jan 15;250:114511
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
Xiao M, Zhang Y, Zhang X, Zhang G, Jin C, Yang J, Wu S, Lu X
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
Cross-talk between autophagy and ferroptosis contributes to the liver injury induced by fluoride via the mtROS-dependent pathway.
Xu W, Hu Z, Zhang J, Tang Y, Xing H, Xu P, Ma Y, Niu Q
Ecotoxicology and environmental safety 2023 Jan 15;250:114490
Ecotoxicology and environmental safety 2023 Jan 15;250:114490
Inhibition of the AKT1/mTOR pathway through SIRT6 over expression downregulated the expression of programmed death-ligand 1 and prolonged overall survival in lung adenocarcinoma.
Yuan ZF, Lin YD, Wu GS, Li L, Yang JP, Zhang JW
Annals of translational medicine 2023 Jan 15;11(1):21
Annals of translational medicine 2023 Jan 15;11(1):21
ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury.
Huo S, Wang Q, Shi W, Peng L, Jiang Y, Zhu M, Guo J, Peng D, Wang M, Men L, Huang B, Lv J, Lin L
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
Cross-Talk between N6-Methyladenosine and Their Related RNAs Defined a Signature and Confirmed m6A Regulators for Diagnosis of Endometriosis.
Wang X, Zhao X, Wang J, Wu H, Cheng Y, Guo Q, Liang T, Zhang G
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway.
Wang F, Zhan Y, Li M, Wang L, Zheng A, Liu C, Wang H, Wang T
ACS pharmacology & translational science 2023 Jan 13;6(1):76-87
ACS pharmacology & translational science 2023 Jan 13;6(1):76-87
Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification.
Xu Y, Xiong Y, Liu Y, Li G, Bai T, Zheng G, Hou X, Song J
Cell & bioscience 2023 Jan 12;13(1):7
Cell & bioscience 2023 Jan 12;13(1):7
CircZBTB46 Protects Acute Myeloid Leukemia Cells from Ferroptotic Cell Death by Upregulating SCD.
Long F, Lin Z, Long Q, Lu Z, Zhu K, Zhao M, Yang M
Cancers 2023 Jan 11;15(2)
Cancers 2023 Jan 11;15(2)
Acceleration of Oral Wound Healing under Diabetes Mellitus Conditions Using Bioadhesive Hydrogel.
Sun J, Chen T, Zhao B, Fan W, Shen Y, Wei H, Zhang M, Zheng W, Peng J, Wang J, Wang Y, Fan L, Chu Y, Chen L, Yang C
ACS applied materials & interfaces 2023 Jan 11;15(1):416-431
ACS applied materials & interfaces 2023 Jan 11;15(1):416-431
Microglia-Derived Spp1 Promotes Pathological Retinal Neovascularization via Activating Endothelial Kit/Akt/mTOR Signaling.
Bai Q, Wang X, Yan H, Wen L, Zhou Z, Ye Y, Jing Y, Niu Y, Wang L, Zhang Z, Su J, Chang T, Dou G, Wang Y, Sun J
Journal of personalized medicine 2023 Jan 11;13(1)
Journal of personalized medicine 2023 Jan 11;13(1)
LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer.
Wu T, Li X, Yan G, Tan Z, Zhao D, Liu S, Wang H, Xiang Y, Chen W, Lu H, Liao X, Li Y, Lu Z
Journal of experimental & clinical cancer research : CR 2023 Jan 10;42(1):14
Journal of experimental & clinical cancer research : CR 2023 Jan 10;42(1):14
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Xing F, Gao H, Chen G, Sun L, Sun J, Qiao X, Xue J, Liu C
Molecular cancer 2023 Jan 10;22(1):6
Molecular cancer 2023 Jan 10;22(1):6
Crosstalk between 5-methylcytosine and N(6)-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma.
Tian Y, Xiao H, Yang Y, Zhang P, Yuan J, Zhang W, Chen L, Fan Y, Zhang J, Cheng H, Deng T, Yang L, Wang W, Chen G, Wang P, Gong P, Niu X, Zhang X
Molecular cancer 2023 Jan 10;22(1):5
Molecular cancer 2023 Jan 10;22(1):5
Pseudogene TDGF1P3 regulates the proliferation and metastasis of colorectal cancer cells via the miR-338-3p-PKM2 axis.
Ni Q, An M, Luo S, Li X, He G, Shen M, Xu L, Huang J, Yan M, Fan Y, Gao Z
Biochemical and biophysical research communications 2023 Jan 1;638:7-13
Biochemical and biophysical research communications 2023 Jan 1;638:7-13
Combined therapy of GABA and sitagliptin prevents high-fat diet impairment of beta-cell function.
Wang Z, Fan L, Ni Y, Wu D, Ma A, Zhao Y, Li J, Cui Q, Zhou Y, Zhang L, Lou YR, Prud'homme GJ, Wang Q
Molecular and cellular endocrinology 2023 Jan 1;559:111755
Molecular and cellular endocrinology 2023 Jan 1;559:111755
IFI204 protects host defense against Staphylococcus aureus-induced pneumonia by promoting extracellular traps formation.
Zhang JG, Chen W, Zhou CK, Ma K, Liu ZZ, Gao Y, Lin XQ, Yang YJ
Experimental cell research 2023 Jan 1;422(1):113415
Experimental cell research 2023 Jan 1;422(1):113415
PRMT6 functionally associates with PRMT5 to promote colorectal cancer progression through epigenetically repressing the expression of CDKN2B and CCNG1.
Chen Y, Liang W, Du J, Ma J, Liang R, Tao M
Experimental cell research 2023 Jan 1;422(1):113413
Experimental cell research 2023 Jan 1;422(1):113413
Effects of chronic realgar exposure on liver lipidome in mice and identification sensitive lipid biomarker model for realgar-induced liver damage.
Huo T, Zhang W, Yang J, Li J, Zhang Y, Guo H, Wu X, Li A, Feng C, Jiang H
Toxicology letters 2023 Jan 1;372:1-13
Toxicology letters 2023 Jan 1;372:1-13
DNA methylation-mediated silencing of Neuronatin promotes hepatocellular carcinoma proliferation through the PI3K-Akt signaling pathway.
Deng Y, Lu L, Liang X, Li J, Zhu D, Huang H, Zhang Y, Zhang X, Chen Y, Liu X, Fu Y
Life sciences 2023 Jan 1;312:121266
Life sciences 2023 Jan 1;312:121266
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Xi H, Hu Z, Han S, Liu X, Wang L, Hu J
Theriogenology 2023 Jan 1;195:103-114
Theriogenology 2023 Jan 1;195:103-114
Infiltrating circulating monocytes provide an important source of BMP4 at the early stage of spinal cord injury.
Shen W, Liu S, Wei X, Wang Y, Yang L
Disease models & mechanisms 2023 Jan 1;16(1)
Disease models & mechanisms 2023 Jan 1;16(1)
Adipose-derived stem cells with miR-150-5p inhibition laden in hydroxyapatite/tricalcium phosphate ceramic powders promote osteogenesis via regulating Notch3 and activating FAK/ERK and RhoA.
Wang F, Wang Q, Zhao Y, Tian Z, Chang S, Tong H, Liu N, Bai S, Li X, Fan J
Acta biomaterialia 2023 Jan 1;155:644-653
Acta biomaterialia 2023 Jan 1;155:644-653
Suppression of lncRNA Snhg1 inhibits high glucose-induced inflammation and proliferation in mouse mesangial cells.
Sheng J, Lu C, Liao Z, Xue M, Zou Z, Feng J, Wu B
Toxicology in vitro : an international journal published in association with BIBRA 2023 Feb;86:105482
Toxicology in vitro : an international journal published in association with BIBRA 2023 Feb;86:105482
α2,6-Sialylation promotes hepatocellular carcinoma cells migration and invasion via enhancement of nSmase2-mediated exosomal miRNA sorting.
Wang L, Chen X, Meng F, Huang T, Wang S, Zheng Z, Zheng G, Li W, Zhang J, Liu Y
Journal of physiology and biochemistry 2023 Feb;79(1):19-34
Journal of physiology and biochemistry 2023 Feb;79(1):19-34
SNHG3 regulates NEIL3 via transcription factor E2F1 to mediate malignant proliferation of hepatocellular carcinoma.
Zhang F, Lu J, Yang J, Dai Q, Du X, Xu Y, Zhang C
Immunogenetics 2023 Feb;75(1):39-51
Immunogenetics 2023 Feb;75(1):39-51
Mitophagy-promoting miR-138-5p promoter demethylation inhibits pyroptosis in sepsis-associated acute lung injury.
Liu F, Yang Y, Peng W, Zhao N, Chen J, Xu Z, Cui Y, Qian K
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Feb;72(2):329-346
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Feb;72(2):329-346
GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis.
Mao Z, Wu Y, Yao P, Xing C
Neoplasma 2023 Feb;70(1):136-144
Neoplasma 2023 Feb;70(1):136-144
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
Pang H, Lei D, Huang J, Guo Y, Fan C
Molecular and cellular probes 2023 Feb;67:101896
Molecular and cellular probes 2023 Feb;67:101896
METTL21C mediates lysine trimethylation of IGF2BP1 to regulate chicken myoblast proliferation.
Wang S, Zhao J, Wang L, Zhang T, Zeng W, Lu H
British poultry science 2023 Feb;64(1):74-80
British poultry science 2023 Feb;64(1):74-80
Expression of transforming growth factor-β1 and autophagy markers in the bladder of rats with neurogenic lower urinary tract injury.
Ma L, Mu Y, Li X, Zhang M, An W, Zeng F
Spinal cord 2023 Feb;61(2):154-159
Spinal cord 2023 Feb;61(2):154-159
Silencing CircEIF3I/miR-526b-5p Axis Epigenetically Targets HGF/c-Met Signal to Hinder the Malignant Growth, Metastasis and Angiogenesis of Hepatocellular Carcinoma.
Liu Y, Xiao X, Wang J, Wang Y, Yu Y
Biochemical genetics 2023 Feb;61(1):48-68
Biochemical genetics 2023 Feb;61(1):48-68
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
Dong K, Zhou WJ, Liu ZH
Journal of periodontal & implant science 2023 Feb;53(1):54-68
Journal of periodontal & implant science 2023 Feb;53(1):54-68
DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.
Yu W, Ma L, Li X
Oncology reports 2023 Feb;49(2)
Oncology reports 2023 Feb;49(2)
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Shen M, Zheng Y, Li G, Chen Y, Huang L, Wu J, Hong C
Neurochemical research 2023 Feb;48(2):579-590
Neurochemical research 2023 Feb;48(2):579-590
Incorporation of glycyrrhizic acid and polyene phosphatidylcholine in lipid nanoparticles ameliorates acute liver injury via delivering p65 siRNA.
Yin Q, Song X, Yang P, Yang W, Li X, Wang X, Wang S
Nanomedicine : nanotechnology, biology, and medicine 2023 Feb;48:102649
Nanomedicine : nanotechnology, biology, and medicine 2023 Feb;48:102649
Tetrahydroberberrubine retards heart aging in mice by promoting PHB2-mediated mitophagy.
Wang L, Tang XQ, Shi Y, Li HM, Meng ZY, Chen H, Li XH, Chen YC, Liu H, Hong Y, Xu HH, Liu L, Zhao L, Han WN, Liu X, Zhang Y
Acta pharmacologica Sinica 2023 Feb;44(2):332-344
Acta pharmacologica Sinica 2023 Feb;44(2):332-344
Pharmacological suppression of NLRP3 inflammasome attenuated the development of autoimmune thyroiditis.
Ding H, Sun X, Xu H
Cellular immunology 2023 Feb;384:104659
Cellular immunology 2023 Feb;384:104659
The long non-coding RNA PANDAR regulates cell proliferation and epithelial-to-mesenchymal transition in glioma.
Guo J, Xiao D, Lin Z, Sui C
Histology and histopathology 2023 Feb;38(2):199-208
Histology and histopathology 2023 Feb;38(2):199-208
OGG1 inhibition suppresses African swine fever virus replication.
Fan J, Lv X, Yang S, Geng S, Yang J, Zhao Y, Zhang Z, Liu Z, Guan G, Luo J, Zeng Q, Yin H, Niu Q
Virologica Sinica 2023 Feb;38(1):96-107
Virologica Sinica 2023 Feb;38(1):96-107
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
EphA4/EphrinB2 signaling mediates pericyte-induced transient glia limitans formation as a secondary protective barrier after subarachnoid hemorrhage in mice.
Zhou J, Guo P, Duan M, Li J, Ru X, Li L, Guo Z, Zhang JH, Feng H, Chen Y, Sun X
Experimental neurology 2023 Feb;360:114293
Experimental neurology 2023 Feb;360:114293
Protective roles of tRNA-derived small RNA tRF-Ile-AAT-019 in pathological progression of psoriasis.
Zeng J, Xie Y, Zhang H, Zhang Y, Zhang Y, Liu L, Hu Q, Zhou L, Gao L, Tan W, Fu Z, Lu J
Experimental dermatology 2023 Feb;32(2):135-145
Experimental dermatology 2023 Feb;32(2):135-145
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Hu H, Li L, Zhang H, Zhang Y, Liu Q, Chen M, Ning J, Pang Y, Hu W, Niu Y, Zhang R
Chemosphere 2023 Feb;315:137749
Chemosphere 2023 Feb;315:137749
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
Wang J, Huang TJ, Mei Y, Luo FF, Xie DH, Peng LX, Liu BQ, Fan ML, Zhang JB, Zheng ST, Qian CN, Huang BJ
Cancer gene therapy 2023 Feb;30(2):375-387
Cancer gene therapy 2023 Feb;30(2):375-387
SNORD88C guided 2'-O-methylation of 28S rRNA regulates SCD1 translation to inhibit autophagy and promote growth and metastasis in non-small cell lung cancer.
Wang K, Wang S, Zhang Y, Xie L, Song X, Song X
Cell death and differentiation 2023 Feb;30(2):341-355
Cell death and differentiation 2023 Feb;30(2):341-355
Effect of stretch frequency on osteogenesis of periodontium during periodontal ligament distraction.
Wang W, Li N, Zhao Y, Wu H, Wang M, Chen X
Orthodontics & craniofacial research 2023 Feb;26(1):53-61
Orthodontics & craniofacial research 2023 Feb;26(1):53-61
IL-17A promotes endothelial cell senescence by up-regulating the expression of FTO through activating JNK signal pathway.
Li N, Luo R, Zhang W, Wu Y, Hu C, Liu M, Jiang D, Jiang Z, Zhao X, Wang Y, Li Q
Biogerontology 2023 Feb;24(1):99-110
Biogerontology 2023 Feb;24(1):99-110
lncRNA SND1-IT1 delivered via intracerebral hemorrhage-derived exosomes affect the growth of human microglia by regulating the miR-124-3p/MTF1 axis.
Wang J, Teng F, Liu S, Pan X, Yang B, Wu W
Journal of cellular physiology 2023 Feb;238(2):366-378
Journal of cellular physiology 2023 Feb;238(2):366-378
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Li Y, She W, Guo T, Huang T, Liu Y, Liu P, Xu X, Wang X, Wang M, Yu C, Liu Y, Wei Y
Biochemical pharmacology 2023 Feb;208:115404
Biochemical pharmacology 2023 Feb;208:115404
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
Chen Z, Sun X, Li X, Liu N
Biochemical pharmacology 2023 Feb;208:115379
Biochemical pharmacology 2023 Feb;208:115379
Molybdenum and Cadmium Co-induce Pyroptosis via Inhibiting Nrf2-Mediated Antioxidant Defense Response in the Brain of Ducks.
Hu Z, Nie G, Luo J, Hu R, Li G, Hu G, Zhang C
Biological trace element research 2023 Feb;201(2):874-887
Biological trace element research 2023 Feb;201(2):874-887
BMP6 regulates AMH expression via SMAD1/5/8 in goat ovarian granulosa cells.
Wang L, Wang Y, Li B, Zhang Y, Song S, Ding W, Xu D, Zhao Z
Theriogenology 2023 Feb;197:167-176
Theriogenology 2023 Feb;197:167-176
Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.
Wang XZ, Wen L, Zhou YP, Huang SN, Yang B, Cheng S, Zeng WB, Mei MJ, Sun JY, Jiang X, Cheng H, Luo MH
PLoS pathogens 2023 Feb;19(2):e1011166
PLoS pathogens 2023 Feb;19(2):e1011166
Exosomal miR-211-5p regulates glucose metabolism, pyroptosis, and immune microenvironment of melanoma through GNA15.
Zeng B, Chen Y, Chen H, Zhao Q, Sun Z, Liu D, Li X, Zhang Y, Wang J, Xing HR
Pharmacological research 2023 Feb;188:106660
Pharmacological research 2023 Feb;188:106660
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Zhu ZH, Jia F, Ahmed W, Zhang GL, Wang H, Lin CQ, Chen WH, Chen LK
Neural regeneration research 2023 Feb;18(2):404-409
Neural regeneration research 2023 Feb;18(2):404-409
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Dai Z, Xia C, Zhao T, Wang H, Tian H, Xu O, Zhu X, Zhang J, Chen P
Materials today. Bio 2023 Feb;18:100512
Materials today. Bio 2023 Feb;18:100512
Hyperlipidemia impacts osteogenesis via lipophagy.
Ji C, Zhang Z, Xu X, Song D, Zhang D
Bone 2023 Feb;167:116643
Bone 2023 Feb;167:116643
Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics.
Xu H, Bensalel J, Raju S, Capobianco E, Lu ML, Wei J
Journal of neurochemistry 2023 Feb;164(4):512-528
Journal of neurochemistry 2023 Feb;164(4):512-528
PLK1 protects intestinal barrier function in sepsis: A translational research.
Cao YY, Li J, Chen Q, Qi YP, Xu QC, He JM, Wang Z, Lu WH
Cytokine 2023 Feb;162:156113
Cytokine 2023 Feb;162:156113
Rutin ameliorates gout via reducing XOD activity, inhibiting ROS production and NLRP3 inflammasome activation in quail.
Wu H, Wang Y, Huang J, Li Y, Lin Z, Zhang B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114175
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114175
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
Tong MQ, Lu CT, Huang LT, Yang JJ, Yang ST, Chen HB, Xue PP, Luo LZ, Yao Q, Xu HL, Zhao YZ
Acta biomaterialia 2023 Feb;157:467-486
Acta biomaterialia 2023 Feb;157:467-486
NOD2 inhibits the proliferation of esophageal adenocarcinoma cells through autophagy.
Li X, Liu S, Jin L, Ma Y, Liu T
Journal of cancer research and clinical oncology 2023 Feb;149(2):639-652
Journal of cancer research and clinical oncology 2023 Feb;149(2):639-652
Tumor-derived endomucin promotes colorectal cancer proliferation and metastasis.
Huang Q, Li XM, Sun JP, Zhou Y
Cancer medicine 2023 Feb;12(3):3222-3236
Cancer medicine 2023 Feb;12(3):3222-3236
Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis.
Li Z, Chen M, Wang Z, Fan Q, Lin Z, Tao X, Wu J, Liu Z, Lin R, Zhao C
Bone & joint research 2023 Feb;12(2):91-102
Bone & joint research 2023 Feb;12(2):91-102
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages.
Mo H, Wang Z, He Z, Wan J, Lu R, Wang C, Chen A, Cheng P
Bone & joint research 2023 Feb;12(2):121-132
Bone & joint research 2023 Feb;12(2):121-132
Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy.
Gao X, Gao LF, Kong XQ, Zhang YN, Jia S, Meng CY
International immunopharmacology 2023 Feb;115:109695
International immunopharmacology 2023 Feb;115:109695
JAK2 inhibitor ameliorates the progression of experimental autoimmune myasthenia gravis and balances Th17/Treg cells via regulating the JAK2/STAT3-AKT/mTOR signaling pathway.
Lu Y, Ma Q, Yu L, Huang H, Liu X, Chen P, Ran H, Liu W
International immunopharmacology 2023 Feb;115:109693
International immunopharmacology 2023 Feb;115:109693
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Zhu D, Kong M, Chen C, Luo J, Kong L
International immunopharmacology 2023 Feb;115:109689
International immunopharmacology 2023 Feb;115:109689
Anoikis patterns exhibit distinct prognostic and immune landscapes in Osteosarcoma.
Zhang Z, Zhu Z, Fu J, Liu X, Mi Z, Tao H, Fan H
International immunopharmacology 2023 Feb;115:109684
International immunopharmacology 2023 Feb;115:109684
Indirubin protects chondrocytes and alleviates OA by inhibiting the MAPK and NF-κB pathways.
Wang X, Guo Z, Lin J, Sun K, Wang G, Hou L, Xu J, Guo J, Zhang X, Guo F, Wei Y
International immunopharmacology 2023 Feb;115:109624
International immunopharmacology 2023 Feb;115:109624
Taxifolin ameliorates cigarette smoke-induced chronic obstructive pulmonary disease via inhibiting inflammation and apoptosis.
Liu X, Ma Y, Luo L, Zeng Z, Zong D, Chen Y
International immunopharmacology 2023 Feb;115:109577
International immunopharmacology 2023 Feb;115:109577
Isothiocyanates attenuate immune checkpoint blockage therapy in gastric cancer via induction of PD-L1 expression.
Zhang Q, Cao W, Yang C, Hong L, Geng S, Han H, Zhong C
The Journal of nutritional biochemistry 2023 Feb;112:109226
The Journal of nutritional biochemistry 2023 Feb;112:109226
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Jiang X, Lu Z, Zhang Q, Yu J, Han D, Liu J, Li P, Li F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics.
Liu FJ, Chen XY, Yang J, Zhao Z, Wang QL, Li P, Jiang Y, Li HJ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154635
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154635
Progranulin deficiency suppresses allergic asthma and enhances efferocytosis via PPAR-γ/MFG-E8 regulation in macrophages.
Huang Q, Weng D, Yao S, Shen H, Gao S, Zhang Y, Huang W, Wang Y, Wang H, Xu W
Immunity, inflammation and disease 2023 Feb;11(2):e779
Immunity, inflammation and disease 2023 Feb;11(2):e779
L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism.
Xu W, Kong Y, Zhang T, Gong Z, Xiao W
Journal of the science of food and agriculture 2023 Feb;103(3):1283-1293
Journal of the science of food and agriculture 2023 Feb;103(3):1283-1293
Regulatory T Cells Overexpressing Peli1 Show Better Efficacy in Repairing Ovarian Endocrine Function in Autoimmune Premature Ovarian Insufficiency.
Wang Y, Zhuo A, Yang Y, Wang Q, Xie J, Ma W, Chen Y, Gao M, Tang L, Fu X
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100005
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100005
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Liu XM, Li Z, Xie XR, Wang JQ, Qiao X, Qiao X, Xie CZ, Xu JY
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis.
Hu Q, Lai J, Chen H, Cai Y, Yue Z, Lin H, Sun L
International journal of molecular sciences 2023 Feb 9;24(4)
International journal of molecular sciences 2023 Feb 9;24(4)
Non-Esterified Fatty Acid-Induced Apoptosis in Bovine Granulosa Cells via ROS-Activated PI3K/AKT/FoxO1 Pathway.
Lei Z, Ali I, Yang M, Yang C, Li Y, Li L
Antioxidants (Basel, Switzerland) 2023 Feb 9;12(2)
Antioxidants (Basel, Switzerland) 2023 Feb 9;12(2)
Genetic dissection of the impact of lncRNA AI662270 during the development of atherosclerosis.
Hong Y, Zhang Y, Chen H, Tang X, Zhao H, Meng Z, Jia X, Liu W, Li X, Wang L, Zhong X, Bai X, Sun H, Kopylov P, Afina B, Shchekochikhin D, Zhang Y, Liu X, Fan Y
Journal of translational medicine 2023 Feb 8;21(1):97
Journal of translational medicine 2023 Feb 8;21(1):97
Study of the inflammatory activating process in the early stage of Fusobacterium nucleatum infected PDLSCs.
Wang Y, Wang L, Sun T, Shen S, Li Z, Ma X, Gu X, Zhang X, Peng A, Xu X, Feng Q
International journal of oral science 2023 Feb 8;15(1):8
International journal of oral science 2023 Feb 8;15(1):8
Anemoside A3 Inhibits Macrophage M2-Like Polarization to Prevent Triple-Negative Breast Cancer Metastasis.
Liu P, Liu Y, Chen L, Fan Z, Luo Y, Cui Y
Molecules (Basel, Switzerland) 2023 Feb 7;28(4)
Molecules (Basel, Switzerland) 2023 Feb 7;28(4)
Administration of Huperzine A microspheres ameliorates myocardial ischemic injury via α7nAChR-dependent JAK2/STAT3 signaling pathway.
Zhang C, Li M, Xie W, Li M, You C, Wang T, Fu F
European journal of pharmacology 2023 Feb 5;940:175478
European journal of pharmacology 2023 Feb 5;940:175478
Cyclic diguanylate analogues: Facile synthesis, STING binding mode and anti-tumor immunity delivered by cytidinyl/cationic lipid.
Sun X, Yu X, Zhao Y, Xing L, Na L, Chen Z, Xiao Z, Dai H, Yu J, Long S, Wang Q, Shi X, Guan Z, Lei M, Yang Z
European journal of medicinal chemistry 2023 Feb 5;247:115053
European journal of medicinal chemistry 2023 Feb 5;247:115053
ZNF385A and ZNF346 Serve as Prognostic Biomarkers Associated with an Inflamed Immunosuppressive Tumor Microenvironment in Hepatocellular Carcinoma.
Peng Q, Li J, Wu Q, Wang P, Kang Z, Deng Y, Xiao Y, Zheng P, Ge F, Chen Y
International journal of molecular sciences 2023 Feb 5;24(4)
International journal of molecular sciences 2023 Feb 5;24(4)
Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
Amos A, Jiang N, Zong D, Gu J, Zhou J, Yin L, He X, Xu Y, Wu L
BMC cancer 2023 Feb 3;23(1):117
BMC cancer 2023 Feb 3;23(1):117
NRXN1 depletion in the medial prefrontal cortex induces anxiety-like behaviors and abnormal social phenotypes along with impaired neurite outgrowth in rat.
Wu D, Zhu J, You L, Wang J, Zhang S, Liu Z, Xu Q, Yuan X, Yang L, Wang W, Tong M, Hong Q, Chi X
Journal of neurodevelopmental disorders 2023 Feb 3;15(1):6
Journal of neurodevelopmental disorders 2023 Feb 3;15(1):6
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
Cheng M, Kanyema MM, Sun Y, Zhao W, Lu Y, Wang J, Li X, Shi C, Wang J, Wang N, Yang W, Jiang Y, Huang H, Yang G, Zeng Y, Wang C, Cao X
Journal of virology 2023 Feb 28;97(2):e0192322
Journal of virology 2023 Feb 28;97(2):e0192322
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
Li WY, Yang F, Li X, Wang LW, Wang Y
World journal of gastroenterology 2023 Feb 28;29(8):1315-1329
World journal of gastroenterology 2023 Feb 28;29(8):1315-1329
Thermoresponsive Ozone-Enriched Spray Gel for Postsurgical Treatment of Hepatocellular Carcinoma.
Zhang Y, Zhang C, Wu B, Li C, Lin J, Huang P
ACS nano 2023 Feb 28;17(4):3518-3527
ACS nano 2023 Feb 28;17(4):3518-3527
Elevated NDC1 expression predicts poor prognosis and correlates with immunity in hepatocellular carcinoma.
Liu Q, Gu L, Qiu J, Qian J
Journal of gastrointestinal oncology 2023 Feb 28;14(1):245-264
Journal of gastrointestinal oncology 2023 Feb 28;14(1):245-264
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
Ayyar BV, Ettayebi K, Salmen W, Karandikar UC, Neill FH, Tenge VR, Crawford SE, Bieberich E, Prasad BVV, Atmar RL, Estes MK
Nature communications 2023 Feb 28;14(1):1148
Nature communications 2023 Feb 28;14(1):1148
KIF2C Facilitates Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma.
Huang X, Zhao F, Wu Q, Wang Z, Ren H, Zhang Q, Wang Z, Xu J
Cancers 2023 Feb 27;15(5)
Cancers 2023 Feb 27;15(5)
Dual regulation of Akt and glutathione caused by isoalantolactone effectively triggers human ovarian cancer cell apoptosis.
Xie Z, Xu J, Xiao D, Lei J, Yu J
Acta biochimica et biophysica Sinica 2023 Feb 25;55(1):62-71
Acta biochimica et biophysica Sinica 2023 Feb 25;55(1):62-71
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Zheng W, Zhou Z, Rui Y, Ye R, Xia F, Guo F, Liu X, Su J, Lou M, Yu XF
Signal transduction and targeted therapy 2023 Feb 24;8(1):79
Signal transduction and targeted therapy 2023 Feb 24;8(1):79
The Investigation of the Molecular Mechanism of Morinda officinalis How in the Treatment of Heart Failure.
Wang A, Guo Y, Ding S, Yu Y, Yuan Z, Zhang H, Liu Y
Frontiers in bioscience (Landmark edition) 2023 Feb 24;28(2):34
Frontiers in bioscience (Landmark edition) 2023 Feb 24;28(2):34
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10.
Peng C, Tu G, Wang J, Wang Y, Wu P, Yu L, Li Z, Yu X
Cell death & disease 2023 Feb 24;14(2):155
Cell death & disease 2023 Feb 24;14(2):155
Comprehensive Analysis of Prognosis and Immune Landscapes Based on Lipid-Metabolism- and Ferroptosis-Associated Signature in Uterine Corpus Endometrial Carcinoma.
Yang P, Lu J, Zhang P, Zhang S
Diagnostics (Basel, Switzerland) 2023 Feb 24;13(5)
Diagnostics (Basel, Switzerland) 2023 Feb 24;13(5)
The pluripotency factor Tex10 finetunes Wnt signaling for PGC and male germline development.
Li D, Yang J, Ma F, Malik V, Zang R, Shi X, Huang X, Zhou H, Wang J
bioRxiv : the preprint server for biology 2023 Feb 24;
bioRxiv : the preprint server for biology 2023 Feb 24;
Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stress.
Ndzie Noah ML, Adzika GK, Mprah R, Adekunle AO, Koda S, Adu-Amankwaah J, Xu Y, Kanwore K, Wowui PI, Sun H
Cell communication and signaling : CCS 2023 Feb 23;21(1):41
Cell communication and signaling : CCS 2023 Feb 23;21(1):41
Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation.
Wang Z, Lauko J, Kijas AW, Gilbert EP, Turunen P, Yegappan R, Zou D, Mata J, Rowan AE
Nature communications 2023 Feb 23;14(1):1029
Nature communications 2023 Feb 23;14(1):1029
TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1.
Wu Z, Ge L, Ma L, Lu M, Song Y, Deng S, Duan P, Du T, Wu Y, Zhang Z, Zhang S
Cell & bioscience 2023 Feb 23;13(1):39
Cell & bioscience 2023 Feb 23;13(1):39
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Ren B, Liu R, He Q, Wu T, Song L, Wang H, Gu J
ACS applied materials & interfaces 2023 Feb 22;15(7):9099-9109
ACS applied materials & interfaces 2023 Feb 22;15(7):9099-9109
Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor.
Hu G, Shi X, Qu X, Han C, Hu A, Jia Z, Yang J, Liu H, Wu Y
International journal of molecular sciences 2023 Feb 21;24(5)
International journal of molecular sciences 2023 Feb 21;24(5)
Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia.
Guo Q, Fan Y, Wang Q, Li B, Qiu W, Qi Y, Pan Z, Zhang S, Zhao S, Yang K, Xu H, Li M, Gao Z, Xu J, Wang H, Wang S, Tang Q, Qiu J, Guo X, Deng L, Zhang P, Zhao R, Xue H, Wang C, Li G
Cell death & disease 2023 Feb 21;14(2):147
Cell death & disease 2023 Feb 21;14(2):147
LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei.
Zhu J, Chen K, Sun YH, Ye W, Liu J, Zhang D, Su N, Wu L, Kou X, Zhao Y, Wang H, Gao S, Kang L
Nature communications 2023 Feb 21;14(1):957
Nature communications 2023 Feb 21;14(1):957
[A convenient and time-saving method for primary culture of mature white adipocytes from mice].
Shentu Z, Gong X, Yang H
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Feb 20;43(2):213-218
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Feb 20;43(2):213-218
[Fibroblasts overpressing WNT2b cause impairment of intestinal mucosal barrier].
Xiao S, Cheng Y, Zhu Y, Tang R, Gu J, Lan L, He Z, Liu D, Geng L, Cheng Y, Gong S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Feb 20;43(2):206-212
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Feb 20;43(2):206-212
Tra2β Enhances Cell Proliferation by Inducing the Expression of Transcription Factor SP1 in Cervical Cancer.
Li MJ, Xiong D, Wang S, Huang H
Biomedical and environmental sciences : BES 2023 Feb 20;36(2):146-159
Biomedical and environmental sciences : BES 2023 Feb 20;36(2):146-159
YTHDF1 Attenuates TBI-Induced Brain-Gut Axis Dysfunction in Mice.
Huang P, Liu M, Zhang J, Zhong X, Zhong C
International journal of molecular sciences 2023 Feb 20;24(4)
International journal of molecular sciences 2023 Feb 20;24(4)
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis.
Zhang L, Fang Z, Cheng G, He M, Lin Y
Cell death & disease 2023 Feb 20;14(2):145
Cell death & disease 2023 Feb 20;14(2):145
ERCC6L facilitates the progression of laryngeal squamous cell carcinoma by the binding of FOXM1 and KIF4A.
Cui M, Chang Y, Wang J, Wu J, Li G, Tan J
Cell death discovery 2023 Feb 2;9(1):41
Cell death discovery 2023 Feb 2;9(1):41
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Deng L, Yang L, Zhu S, Li M, Wang Y, Cao X, Wang Q, Guo L
Cell death discovery 2023 Feb 2;9(1):40
Cell death discovery 2023 Feb 2;9(1):40
Alpha-kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway.
Cui X, Li Y, Yuan S, Huang Y, Chen X, Han Y, Liu Z, Li Z, Xiao Y, Wang Y, Sun L, Liu H, Zhu X
Biological research 2023 Feb 2;56(1):5
Biological research 2023 Feb 2;56(1):5
Malvidin-3-O-Glucoside Ameliorates Cadmium-Mediated Cell Dysfunction in the Estradiol Generation of Human Granulosa Cells.
Liang S, Li X, Liu R, Hu J, Li Y, Sun J, Bai W
Nutrients 2023 Feb 2;15(3)
Nutrients 2023 Feb 2;15(3)
Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection.
Hu YJ, Song GY, Zhang F, Zhang N, Wang F, Wang JL, Wang X, Wang TY, Li YF, Yan YD, Dou WT, Cheng CY, Xu P
iScience 2023 Feb 17;26(2):105932
iScience 2023 Feb 17;26(2):105932
LincRNA ZNF529-AS1 inhibits hepatocellular carcinoma via FBXO31 and predicts the prognosis of hepatocellular carcinoma patients.
Ma Y, Sun WL, Ma SS, Zhao G, Liu Z, Lu Z, Zhang D
BMC bioinformatics 2023 Feb 17;24(1):54
BMC bioinformatics 2023 Feb 17;24(1):54
MiR-21 Is Induced by Hypoxia and Down-Regulates RHOB in Prostate Cancer.
Angel CZ, Stafford MYC, McNally CJ, Nesbitt H, McKenna DJ
Cancers 2023 Feb 17;15(4)
Cancers 2023 Feb 17;15(4)
Oxymatrine attenuated isoproterenol-induced heart failure via the TLR4/NF-κB and MAPK pathways in vivo and in vitro.
Sun H, Bai J, Sun Y, Zhen D, Fu D, Wang Y, Wei C
European journal of pharmacology 2023 Feb 15;941:175500
European journal of pharmacology 2023 Feb 15;941:175500
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis.
Lou J, Zhang H, Huang Q, Chen C, Wang W, Niu J, Xu J, Ren T, Huang Y, Tang X, Guo W
Cell death discovery 2023 Feb 15;9(1):64
Cell death discovery 2023 Feb 15;9(1):64
Metformin regulates autophagy via LGMN to inhibit choriocarcinoma.
Tu W, Qin M, Li Y, Wu W, Tong X
Gene 2023 Feb 15;853:147090
Gene 2023 Feb 15;853:147090
RBM10 recruits METTL3 to induce N6-methyladenosine-MALAT1-dependent modification, inhibiting the invasion and migration of NSCLC.
Cao Y, Di X, Cong S, Tian C, Wang Y, Jin X, Zhao M, Zhou X, Li R, Wang K
Life sciences 2023 Feb 15;315:121359
Life sciences 2023 Feb 15;315:121359
Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.
Wang HY, Wang FZ, Chang R, Wang Q, Liu SY, Cheng ZX, Gao Q, Zhou H, Zhou YB
International journal of molecular sciences 2023 Feb 15;24(4)
International journal of molecular sciences 2023 Feb 15;24(4)
Hydrogen Sulfide Inhibited Sympathetic Activation in D-Galactose-Induced Aging Rats by Upregulating Klotho and Inhibiting Inflammation in the Paraventricular Nucleus.
Yu H, Yu Q, Mi Y, Wang P, Jin S, Xiao L, Guo Q, Wu Y
Biomedicines 2023 Feb 15;11(2)
Biomedicines 2023 Feb 15;11(2)
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Guo TT, Zhang Z, Sun Y, Zhu RY, Wang FX, Ma LJ, Jiang L, Liu HD
Nutrients 2023 Feb 13;15(4)
Nutrients 2023 Feb 13;15(4)
m6A contributes to a pro-survival state in GC-2 cells by facilitating DNA damage repair: Novel perspectives on the mechanism underlying DEHP genotoxicity in male germ cells.
Fu H, Zhu X, Di Q, Sun J, Jiang Q, Xu Q
The Science of the total environment 2023 Feb 10;859(Pt 2):160432
The Science of the total environment 2023 Feb 10;859(Pt 2):160432
To explore the regulatory role of Wnt/P53/Caspase3 signal in mouse ovarian development based on LFQ proteomics.
Ma Y, Du C, Xie X, Zhang Y, Wang C, Xu J, Xia G, Yang Y
Journal of proteomics 2023 Feb 10;272:104772
Journal of proteomics 2023 Feb 10;272:104772
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy.
Zhu TT, Wang H, Gu HW, Ju LS, Wu XM, Pan WT, Zhao MM, Yang JJ, Liu PM
Journal of nanobiotechnology 2023 Feb 10;21(1):52
Journal of nanobiotechnology 2023 Feb 10;21(1):52
HDAC Inhibitors Alleviate Uric Acid-Induced Vascular Endothelial Cell Injury by Way of the HDAC6/FGF21/PI3K/AKT Pathway.
Wang K, Zhang Y, Zhou M, Du Y, Li P, Guan C, Huang Z
Journal of cardiovascular pharmacology 2023 Feb 1;81(2):150-164
Journal of cardiovascular pharmacology 2023 Feb 1;81(2):150-164
ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries.
Ma Z, Mao C, Jia Y, Yu F, Xu P, Tan Y, Zou QH, Zhou XJ, Kong W, Fu Y
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):291-308
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):291-308
Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis.
Liu WC, Chiu HW, Chou CL, Chiu YJ, Lee YH
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120871
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120871
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Zhou G, Wang J, Ren L, Liu J, Li X, Zhang Y, Sang Y, Gao L, Li Y, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Core-shell SERS nanotags-based western blot.
Liu B, Tang H, Liu Q, Wang W, Li H, Zheng S, Sun F, Zhao X
Talanta 2023 Feb 1;253:123888
Talanta 2023 Feb 1;253:123888
Theilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor, Melanoma Differentiation-Associated Gene 5, and Impairs Double-Stranded RNA-Mediated IFN Response.
Miyamoto M, Himeda T, Ishihara K, Okuwa T, Kobayashi D, Nameta M, Karasawa Y, Chunhaphinyokul B, Yoshida Y, Tanaka N, Higuchi M, Komuro A
Journal of immunology (Baltimore, Md. : 1950) 2023 Feb 1;210(3):335-347
Journal of immunology (Baltimore, Md. : 1950) 2023 Feb 1;210(3):335-347
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
Lin D, Sun Q, Liu Z, Pan J, Zhu J, Wang S, Jia S, Zheng M, Li X, Gong F
Free radical biology & medicine 2023 Feb 1;195:199-218
Free radical biology & medicine 2023 Feb 1;195:199-218
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Chen JW, Shan TK, Wei TW, Jiang QQ, Du C, Gu LF, Yang TT, Zhou LH, Wang SB, Bao YL, Wang H, Ji Y, Xie LP, Gu AH, Sun CQ, Wang QM, Wang LS
Archives of toxicology 2023 Dec;97(12):3209-3226
Archives of toxicology 2023 Dec;97(12):3209-3226
Heat stress suppresses MnSOD expression via p53-Sp1 interaction and induces oxidative stress damage in endothelial cells: Protective effects of MitoQ10 and Pifithrin-α.
Gong J, Sun P, Li L, Zou Z, Wu Q, Sun L, Li H, Gu Z, Su L
Heliyon 2023 Dec;9(12):e22805
Heliyon 2023 Dec;9(12):e22805
Inhibited Expression of NLRP12 Promotes the Development of Triple-Negative Breast Cancer by Activating the NF-κB Pathway.
Kuang W, Gu Q, Zhou Y, Xiao X, He D, Deng Q
Cell biochemistry and biophysics 2023 Dec;81(4):727-735
Cell biochemistry and biophysics 2023 Dec;81(4):727-735
BCLAF1-induced HIF-1α accumulation under normoxia enhances PD-L1 treatment resistances via BCLAF1-CUL3 complex.
Yao B, Lu Y, Li Y, Bai Y, Wei X, Yang Y, Yao D
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4279-4292
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4279-4292
Long noncoding RNA RMRP ameliorates doxorubicin-induced apoptosis by interacting with PFN1 in a P53-Dependent manner.
Li J, Zhou L, Jiang Y, Gao H, Maierhaba T, Gong H
Molecular and cellular probes 2023 Dec;72:101937
Molecular and cellular probes 2023 Dec;72:101937
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells.
Biber JC, Sullivan A, Brazzo JA 3rd, Heo Y, Tumenbayar BI, Krajnik A, Poppenberg KE, Tutino VM, Heo SJ, Kolega J, Lee K, Bae Y
APL bioengineering 2023 Dec;7(4):046108
APL bioengineering 2023 Dec;7(4):046108
Survivin regulates intracellular stiffness and extracellular matrix production in vascular smooth muscle cells.
Krajnik A, Nimmer E, Brazzo JA 3rd, Biber JC, Drewes R, Tumenbayar BI, Sullivan A, Pham K, Krug A, Heo Y, Kolega J, Heo SJ, Lee K, Weil BR, Kim DH, Gupte SA, Bae Y
APL bioengineering 2023 Dec;7(4):046104
APL bioengineering 2023 Dec;7(4):046104
Vitamin D Receptor Activation Attenuates Olanzapine-Induced Dyslipidemia in Mice Through Alleviating Hepatic Endoplasmic Reticulum Stress.
Dang R, Wang J, Tang M, Han W, Jiang P
Advanced biology 2023 Dec;7(12):e2300228
Advanced biology 2023 Dec;7(12):e2300228
Simvastatin inhibits proliferation and promotes apoptosis of oral squamous cell carcinoma through KLF2 signal.
Kou Y, Zhang Y, Rong X, Yang P, Wang C, Zhou Q, Liu H, Liu B, Li M
Journal of oral biosciences 2023 Dec;65(4):347-355
Journal of oral biosciences 2023 Dec;65(4):347-355
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport.
Zhao N, Deng G, Yuan PX, Zhang YF, Jiang LY, Zhao X, Song BL
Journal of lipid research 2023 Dec;64(12):100465
Journal of lipid research 2023 Dec;64(12):100465
JianPi-QingHua formula attenuates nonalcoholic fatty liver disease by regulating the AMPK/SIRT1/NF-κB pathway in high-fat-diet-fed C57BL/6 mice.
Tian J, Cai M, Jin S, Chen Q, Xu J, Guo Q, Yan Z, Han X, Lu H
Pharmaceutical biology 2023 Dec;61(1):647-656
Pharmaceutical biology 2023 Dec;61(1):647-656
Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor.
Zhang J, Zhang C, Miao L, Meng Z, Gu N, Song G
Pharmaceutical biology 2023 Dec;61(1):449-458
Pharmaceutical biology 2023 Dec;61(1):449-458
Prokinetic effects of Citrus reticulata and Citrus aurantium extract with/without Bupleurum chinense using multistress-induced delayed gastric emptying models.
Gong Y, Liang X, Dai Y, Huang X, Su Q, Ma Y, Chen F, Wang S
Pharmaceutical biology 2023 Dec;61(1):345-355
Pharmaceutical biology 2023 Dec;61(1):345-355
Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway.
Lin P, Qiu F, Wu M, Xu L, Huang D, Wang C, Yang X, Ye C
Pharmaceutical biology 2023 Dec;61(1):23-29
Pharmaceutical biology 2023 Dec;61(1):23-29
Luteolin alleviated neutrophilic asthma by inhibiting IL-36γ secretion-mediated MAPK pathways.
Qiao XR, Feng T, Zhang D, Zhi LL, Zhang JT, Liu XF, Pan Y, Xu JW, Cui WJ, Dong L
Pharmaceutical biology 2023 Dec;61(1):165-176
Pharmaceutical biology 2023 Dec;61(1):165-176
Novel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/β-catenin signalling pathway.
Qi Z, Yan Z, Zhu K, Wang Y, Fan Y, Li T, Zhang J
Pharmaceutical biology 2023 Dec;61(1):1364-1373
Pharmaceutical biology 2023 Dec;61(1):1364-1373
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
Liu J, Li L, Han X, Chen Y, Diao J
Pharmaceutical biology 2023 Dec;61(1):1332-1342
Pharmaceutical biology 2023 Dec;61(1):1332-1342
miR-141-3p alleviates ulcerative colitis by targeting SUGT1 to inhibit colonic epithelial cell pyroptosis.
Yan R, Liang X, Hu J
Autoimmunity 2023 Dec;56(1):2220988
Autoimmunity 2023 Dec;56(1):2220988
Binding of berberine to PEBP1 synergizes with sorafenib to induce the ferroptosis of hepatic stellate cells.
Xie Z, Zhou Y, Lin M, Huang C
Amino acids 2023 Dec;55(12):1867-1878
Amino acids 2023 Dec;55(12):1867-1878
Astragaloside IV ameliorate acute alcohol-induced liver injury in mice via modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway.
Wu S, Wen F, Zhong X, Du W, Chen M, Wang J
Annals of medicine 2023 Dec;55(1):2216942
Annals of medicine 2023 Dec;55(1):2216942
Dexmedetomidine enables copper homeostasis in cerebral ischemia/reperfusion via ferredoxin 1.
Guo Q, Ma M, Yu H, Han Y, Zhang D
Annals of medicine 2023 Dec;55(1):2209735
Annals of medicine 2023 Dec;55(1):2209735
Study on tumour cell-derived hybrid exosomes as dasatinib nanocarriers for pancreatic cancer therapy.
Zhou X, Zhuang Y, Liu X, Gu Y, Wang J, Shi Y, Zhang L, Li R, Zhao Y, Chen H, Li J, Yao H, Li L
Artificial cells, nanomedicine, and biotechnology 2023 Dec;51(1):532-546
Artificial cells, nanomedicine, and biotechnology 2023 Dec;51(1):532-546
An impaired ubiquitin-proteasome system increases APOBEC3A abundance.
Coxon M, Dennis MA, Dananberg A, Collins CD, Wilson HE, Meekma J, Savenkova MI, Ng D, Osbron CA, Mertz TM, Goodman AG, Duttke SH, Maciejowski J, Roberts SA
NAR cancer 2023 Dec;5(4):zcad058
NAR cancer 2023 Dec;5(4):zcad058
Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC.
Song X, Wang L, Tang W, Yuan L, Liu Q, Li J, Fan D
Archives of pharmacal research 2023 Dec;46(11-12):924-938
Archives of pharmacal research 2023 Dec;46(11-12):924-938
Chitosan oligosaccharide attenuates acute kidney injury and renal interstitial fibrosis induced by ischemia-reperfusion.
Yin S, Liu J, Zhao X, Dong H, Cao Y, Zhang S, Dong X, Zhang G, Jin S, Shi W, Xiang F, Gong J, Wang Z, Han B, Zhang N, Tan X, Wang Z
Renal failure 2023 Dec;45(1):2238831
Renal failure 2023 Dec;45(1):2238831
Apelin-13 alleviates contrast-induced acute kidney injury by inhibiting endoplasmic reticulum stress.
Liu Q, Duan SB, Wang L, Luo XQ, Wang HS, Deng YH, Wu X, Wu T, Yan And P, Kang YX
Renal failure 2023 Dec;45(1):2179852
Renal failure 2023 Dec;45(1):2179852
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells.
Ding W, Wang JX, Wu JZ, Liu AC, Jiang LL, Zhang HC, Meng Y, Liu BY, Peng GJ, Lou EZ, Mao Q, Zhou H, Tang DL, Chen X, Liu JB, Shi XP
Acta pharmacologica Sinica 2023 Dec;44(12):2537-2548
Acta pharmacologica Sinica 2023 Dec;44(12):2537-2548
LOXL3 Inhibits Autophagy of Chondrocytes by Activating Rheb in Osteoarthritis.
Zheng GP, Liu C, Zhang L, Zhong Q, Zhang Y, Huang ZM
Current medical science 2023 Dec;43(6):1195-1200
Current medical science 2023 Dec;43(6):1195-1200
PPARβ/δ activation protects against hepatic ischaemia-reperfusion injury.
Qian B, Wang C, Li X, Ma P, Dong L, Shen B, Wu H, Li N, Kang K, Ma Y
Liver international : official journal of the International Association for the Study of the Liver 2023 Dec;43(12):2808-2823
Liver international : official journal of the International Association for the Study of the Liver 2023 Dec;43(12):2808-2823
Aggf1 Specifies Hemangioblasts at the Top of Regulatory Hierarchy via Npas4l and mTOR-S6K-Emp2-ERK Signaling.
Yang Z, Guo D, Zhao J, Li J, Zhang R, Zhang Y, Xu C, Ke T, Wang QK
Arteriosclerosis, thrombosis, and vascular biology 2023 Dec;43(12):2348-2368
Arteriosclerosis, thrombosis, and vascular biology 2023 Dec;43(12):2348-2368
Peripheral BDNF Regulates Somatosensory-Sympathetic Coupling in Brachial Plexus Avulsion-Induced Neuropathic Pain.
Xian H, Guo H, Liu YY, Zhang JL, Hu WC, Yu MJ, Zhao R, Xie RG, Zhang H, Cong R
Neuroscience bulletin 2023 Dec;39(12):1789-1806
Neuroscience bulletin 2023 Dec;39(12):1789-1806
Talin1 regulates glucose metabolism and endometrial receptivity via GLUT-4 in patients with polycystic ovary syndrome and insulin resistance.
Li J, Chen S, Qin R, Liu X, Fan L, Wei M, Wei J, Lin J, Zheng F
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Dec;39(1):2231085
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Dec;39(1):2231085
MiR-5195-3p functions as a tumor suppressor by targeting RHBDD1 in ovarian cancer.
Wang Z, Zhang X, Liu Y, Shi X, Li L, Jia Y, Wu F, Cui H, Li L
Histology and histopathology 2023 Dec;38(12):1403-1413
Histology and histopathology 2023 Dec;38(12):1403-1413
Activation of moderate autophagy promotes survival of fat graft.
Pei SJ, Zhu YZ, Yang JM, Zhang MC, Shi CL, Ding Y, Yi YY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23289
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23289
Periostin promotes extensive neovascularization in placenta accreta spectrum disorders via Notch signaling.
Li R, Wang W, Qiu X, He M, Tang X, Zhong M
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2023 Dec;36(2):2264447
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2023 Dec;36(2):2264447
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
Bu H, Wang B, Wu Y, Li P, Cui Y, Jiang X, Yu X, Liu B, Tang M
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
HIF-1α promotes astrocytic production of macrophage migration inhibitory factor following spinal cord injury.
Hao H, Hou Y, Li A, Niu L, Li S, He B, Zhang X, Song H, Cai R, Zhou Y, Yao C, Wang Y, Wang Y
CNS neuroscience & therapeutics 2023 Dec;29(12):3802-3814
CNS neuroscience & therapeutics 2023 Dec;29(12):3802-3814
Cystathionine γ-lyase S-sulfhydrates SIRT1 to attenuate myocardial death in isoprenaline-induced heart failure.
Wu D, Sun Y, Gu Y, Zhu D
Redox report : communications in free radical research 2023 Dec;28(1):2174649
Redox report : communications in free radical research 2023 Dec;28(1):2174649
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Wang T, Zhou Y, Bao H, Liu B, Wang M, Wang L, Pan T
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
hsa-miR-1301-3p Promotes the Proliferation and Migration of Nonsmall Cell Lung Cancer Cells and Reduces Radiosensitivity via Targeting Homeodomain-Only Protein Homeobox.
Qu M, Jin Z, Xu Y, Sun W, Luo Y, Zhang N, Huang Z, Han L, Gong Y, Xie C
Genetic testing and molecular biomarkers 2023 Dec;27(12):393-405
Genetic testing and molecular biomarkers 2023 Dec;27(12):393-405
Exploring the mechanism of resistance to vincristine in breast cancer cells using transcriptome sequencing technology.
Chen Y, Yang L, Wang C, Wang C
Oncology letters 2023 Dec;26(6):502
Oncology letters 2023 Dec;26(6):502
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
Zhao Y, Lin Y, Wang B, Liu F, Zhao D, Wang W, Ren H, Wang J, Xu Z, Yan C, Ji K
Neuromolecular medicine 2023 Dec;25(4):489-500
Neuromolecular medicine 2023 Dec;25(4):489-500
Porous gelatin microspheres implanted with adipose mesenchymal stromal cells promote angiogenesis via protein kinase B/endothelial nitric oxide synthase signaling pathway in bladder reconstruction.
Zhao J, Yang T, Zhou L, Liu J, Mao L, Jia R, Zhao F
Cytotherapy 2023 Dec;25(12):1317-1330
Cytotherapy 2023 Dec;25(12):1317-1330
Zinc Overload Induces Damage to H9c2 Cardiomyocyte Through Mitochondrial Dysfunction and ROS-Mediated Mitophagy.
Yang Y, Wang P, Guo J, Ma T, Hu Y, Huang L, Xing B, He Y, Xi J
Cardiovascular toxicology 2023 Dec;23(11-12):388-405
Cardiovascular toxicology 2023 Dec;23(11-12):388-405
BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2.
Duan B, Zhou X, Zhang X, Qiu F, Zhang S, Chen Y, Yang J, Wang J, Tan W
Biochemical pharmacology 2023 Dec;218:115877
Biochemical pharmacology 2023 Dec;218:115877
Ginsenoside Rb2 improves heart failure by down-regulating miR-216a-5p to promote autophagy and inhibit apoptosis and oxidative stress.
Peng Y, Liao B, Zhou Y, Zeng W
Journal of applied biomedicine 2023 Dec;21(4):180-192
Journal of applied biomedicine 2023 Dec;21(4):180-192
Metformin attenuates inflammation and boosts autophagy in the liver and intestine of chronologically aged rats.
Kuai Z, Chao X, He Y, Ren W
Experimental gerontology 2023 Dec;184:112331
Experimental gerontology 2023 Dec;184:112331
ZnO nanoparticles impair autophagic flux and cell viability through the TRIM16-NRF2-p62 pathway in inflammatory keratinocytes.
Wang M, Zheng H, Chen J, Tang Y, Feng M, Li L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114177
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114177
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
Xu Q, Cao Y, Zhong X, Qin X, Feng J, Peng H, Su Y, Ma Z, Zhou S
British journal of pharmacology 2023 Dec;180(23):3024-3044
British journal of pharmacology 2023 Dec;180(23):3024-3044
NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status.
Zhang H, Shan W, Yang Z, Zhang Y, Wang M, Gao L, Zeng L, Zhao Q, Liu J
Epigenetics 2023 Dec;18(1):2188667
Epigenetics 2023 Dec;18(1):2188667
Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals.
Zhao Y, Wang H, He T, Ma B, Chen G, Tzeng C
Journal of cell communication and signaling 2023 Dec;17(4):1335-1354
Journal of cell communication and signaling 2023 Dec;17(4):1335-1354
Synergistic inhibition of NUDT21 by secretory S100A11 and exosomal miR-487a-5p promotes melanoma oligo- to poly-metastatic progression.
Zeng B, Chen Y, Chen H, Zhao Q, Sun Z, Liu D, Li X, Zhang Y, Wang J, Xing HR
Molecular oncology 2023 Dec;17(12):2743-2766
Molecular oncology 2023 Dec;17(12):2743-2766
Protocatechuic aldehyde increases pericyte coverage and mitigates pericyte damage to enhance the atherosclerotic plaque stability.
Zhang L, Li Y, Yang W, Lin L, Li J, Liu D, Li C, Wu J, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115742
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115742
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression.
Liu Y, Lv B, Tang K, Qu H, Yu F, Shi Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115677
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115677
Antinociceptive and neuroprotective effect of echinacoside on peripheral neuropathic pain in mice through inhibiting P2X7R/FKN/CX3CR1 pathway.
Liu N, Zhang GX, Zhu CH, Lan XB, Tian MM, Zheng P, Peng XD, Li YX, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115675
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115675
Increasing expression of STING by ERα antagonizes LCN2 downregulation during chronic endometritis.
Chu M, He S, Zhao H, Yin S, Liu Z, Zhang W, Liu X, Bao H
Journal of reproductive immunology 2023 Dec;160:104167
Journal of reproductive immunology 2023 Dec;160:104167
Therapeutic potential and protective role of GRK6 overexpression in pulmonary arterial hypertension.
Liu C, Wan N, Wei L, Rong W, Zhu W, Xie M, Zhang Y, Liu Z, Jing Q, Lyu A
Vascular pharmacology 2023 Dec;153:107233
Vascular pharmacology 2023 Dec;153:107233
MicroRNA-367-3p directly targets RAB23 and inhibits proliferation, migration and invasion of bladder cancer cells and increases cisplatin sensitivity.
Wei X, Jiang Y, Yang G, Chang T, Sun G, Chen S, Wu S, Liu R
Journal of cancer research and clinical oncology 2023 Dec;149(20):17807-17821
Journal of cancer research and clinical oncology 2023 Dec;149(20):17807-17821
LRRC8A promotes Glaesserella parasuis cytolethal distending toxin-induced p53-dependent apoptosis in NPTr cells.
Mao W, Wang Z, Wen S, Lin Y, Gu J, Sun J, Wang H, Cao Q, Xu Y, Xu X, Cai X
Virulence 2023 Dec;14(1):2287339
Virulence 2023 Dec;14(1):2287339
Retracted Article: Exosomes from bone marrow mesenchymal stem cells promoted osteogenic differentiation by delivering miR-196a that targeted Dickkopf-1 to activate Wnt/β-catenin pathway.
Peng Z, Lu S, Lou Z, Li Z, Li S, Yang K, Li C
Bioengineered 2023 Dec;14(1):1996015
Bioengineered 2023 Dec;14(1):1996015
USP7 promotes non-small-cell lung cancer cell glycolysis and survival by stabilizing and activating c-Abl.
He Y, Jiang S, Zhong Y, Wang X, Cui Y, Liang J, Sun Y, Zhu Z, Huang Z, Mao X
Clinical and translational medicine 2023 Dec;13(12):e1509
Clinical and translational medicine 2023 Dec;13(12):e1509
Artesunate alleviates diabetic retinopathy by activating autophagy via the regulation of AMPK/SIRT1 pathway.
Li L, Chen J, Zhou Y, Zhang J, Chen L
Archives of physiology and biochemistry 2023 Dec;129(4):943-950
Archives of physiology and biochemistry 2023 Dec;129(4):943-950
In vitro and in vivo killing effects of methionine enkephalin on osteosarcoma.
Huang H, Wang X, Zhang S, Bai X, Griffin N, Shan Y, Shan F
International immunopharmacology 2023 Dec;125(Pt B):111226
International immunopharmacology 2023 Dec;125(Pt B):111226
Diabetic and nondiabetic BMSC-derived exosomes affect bone regeneration via regulating miR-17-5p/SMAD7 axis.
Li Z, Zhang B, Shang J, Wang Y, Jia L, She X, Xu X, Zhang D, Guo J, Zhang F
International immunopharmacology 2023 Dec;125(Pt B):111190
International immunopharmacology 2023 Dec;125(Pt B):111190
Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis.
Luo S, Luo R, Lu H, Zhang R, Deng G, Luo H, Yu X, Wang C, Zhang H, Zhang Y, Huang W, Sun J, Liu Y, Huang F, Lei Z
International immunopharmacology 2023 Dec;125(Pt B):111132
International immunopharmacology 2023 Dec;125(Pt B):111132
Sodium alginate combined with oxymatrine ameliorates CCl(4)-induced chemical hepatic fibrosis in mice.
He C, Wang W, Wei G, Wang Y, Wei Y, Wang J, Zhang Z
International immunopharmacology 2023 Dec;125(Pt A):111144
International immunopharmacology 2023 Dec;125(Pt A):111144
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells.
Feng Q, Hu K, Hu H, Lu Y, Zhang H, Wang G, Zhang Q, Xu Z, Gao X, Jia X, Zhu H, Song D, Yi H, Peng Y, Wu X, Li B, Zhu W, Shi J
International immunopharmacology 2023 Dec;125(Pt A):111139
International immunopharmacology 2023 Dec;125(Pt A):111139
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Liu X, Jin S, Liu J, Xu X
Acta histochemica 2023 Dec;125(8):152102
Acta histochemica 2023 Dec;125(8):152102
PGC1α deficiency reverses cholestasis-induced liver injury via attenuating hepatic inflammation and promoting bile duct remodeling.
Li D, Ye C, Liu P, Sun T, Qin Y, Wan X
Acta histochemica 2023 Dec;125(8):152097
Acta histochemica 2023 Dec;125(8):152097
ABTB1 facilitates the replication of influenza A virus by counteracting TRIM4-mediated degradation of viral NP protein.
Shi W, Shan Z, Jiang L, Wang G, Wang X, Chang Y, Hu Y, Wang B, Li Q, Wang Y, Deng G, Shi J, Jiang Y, Zeng X, Tian G, Chen H, Li C
Emerging microbes & infections 2023 Dec;12(2):2270073
Emerging microbes & infections 2023 Dec;12(2):2270073
CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis.
Chen X, Zheng J, Liu C, Li T, Wang X, Li X, Bao M, Li J, Huang L, Zhang Z, Bu Z, Weng C
Emerging microbes & infections 2023 Dec;12(2):2220575
Emerging microbes & infections 2023 Dec;12(2):2220575
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc.
Bi X, Zhang M, Zhou J, Yan X, Cheng L, Luo L, Huang C, Yin Z
Cellular signalling 2023 Dec;112:110913
Cellular signalling 2023 Dec;112:110913
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Han C, Li Z, Liu R, Zhao Z, Wang Y, Zuo X, Zhang Y, Geng Z, Huang H, Pan X, Li W
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
lncRNA GPRC5D-AS1 as a ceRNA inhibits skeletal muscle aging by regulating miR-520d-5p.
Yu M, He X, Liu T, Li J
Aging 2023 Dec 9;15(23):13980-13997
Aging 2023 Dec 9;15(23):13980-13997
Synergistic effect of cryptotanshinone and temozolomide treatment against human glioblastoma cells.
Zhu S, Guo J, Yu L, Liu J, Chen J, Xin J, Zhang Y, Luo J, Duan C
Scientific reports 2023 Dec 9;13(1):21835
Scientific reports 2023 Dec 9;13(1):21835
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression.
Wang X, Gao F, Cheng C, Zhang Y
Functional & integrative genomics 2023 Dec 8;24(1):1
Functional & integrative genomics 2023 Dec 8;24(1):1
Development of an iron overload HepG2 cell model using ferrous ammonium citrate.
Abbasi U, Abbina S, Gill A, Kizhakkedathu JN
Scientific reports 2023 Dec 8;13(1):21915
Scientific reports 2023 Dec 8;13(1):21915
CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity.
Zhang G, Jiang P, Tang W, Wang Y, Qiu F, An J, Zheng Y, Wu D, Zhou J, Neculai D, Shi Y, Sheng W
Molecular cell 2023 Dec 7;83(23):4370-4385.e9
Molecular cell 2023 Dec 7;83(23):4370-4385.e9
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Pien Tze Huang alleviates Concanavalin A-induced autoimmune hepatitis by regulating intestinal microbiota and memory regulatory T cells.
Zeng X, Liu MH, Xiong Y, Zheng LX, Guo KE, Zhao HM, Yin YT, Liu DY, Zhou BG
World journal of gastroenterology 2023 Dec 7;29(45):5988-6016
World journal of gastroenterology 2023 Dec 7;29(45):5988-6016
A chromosome-level genome assembly for the Silkie chicken resolves complete sequences for key chicken metabolic, reproductive, and immunity genes.
Zhu F, Yin ZT, Zhao QS, Sun YX, Jie YC, Smith J, Yang YZ, Burt DW, Hincke M, Zhang ZD, Yuan MD, Kaufman J, Sun CJ, Li JY, Shao LW, Yang N, Hou ZC
Communications biology 2023 Dec 6;6(1):1233
Communications biology 2023 Dec 6;6(1):1233
CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation.
Chen Z, Li Y, He K, Yang J, Deng Q, Chen Y, Fu Z
Journal of experimental & clinical cancer research : CR 2023 Dec 6;42(1):334
Journal of experimental & clinical cancer research : CR 2023 Dec 6;42(1):334
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Chen Y, He Z, Yang S, Chen C, Xiong W, He Y, Liu S
Journal of translational medicine 2023 Dec 6;21(1):886
Journal of translational medicine 2023 Dec 6;21(1):886
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
Liu C, Zhao M, Chen J, Xu L, Wang K, Li G
European journal of pharmacology 2023 Dec 5;960:176121
European journal of pharmacology 2023 Dec 5;960:176121
Shizhifang ameliorates pyroptosis of renal tubular epithelial cells in hyperuricemia through inhibiting NLRP3 inflammasome.
Zhou J, Wang C, Zhang X, Wu Z, Wu Y, Li D, Gao J
Journal of ethnopharmacology 2023 Dec 5;317:116777
Journal of ethnopharmacology 2023 Dec 5;317:116777
Anti-inflammatory effect and component analysis of Chaihu Qingwen granules.
Zhou Y, Li QX, Liao ZZ, Liu Y, Ouyang Y, Jiang WJ, Tang MT, Hu JF, Zhang W
Journal of ethnopharmacology 2023 Dec 5;317:116763
Journal of ethnopharmacology 2023 Dec 5;317:116763
The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptor.
Gao L, Zhao JX, Qin XM, Zhao J
Journal of ethnopharmacology 2023 Dec 5;317:116762
Journal of ethnopharmacology 2023 Dec 5;317:116762
A New HEK293 Cell with CR2 Region of E1A Gene Deletion Prevents the Emergence of Replication-Competent Adenovirus.
Lian X, Zhao X, Zhong J, Zhang C, Chu Y, Wang Y, Lu S, Wang Z
Cancers 2023 Dec 5;15(24)
Cancers 2023 Dec 5;15(24)
Alternative splicing of histone demethylase Kdm6bb mediates temperature-induced sex reversal in the Nile tilapia.
Yao ZL, Fang QF, Li JY, Zhou M, Du S, Chen HJ, Wang H, Jiang SJ, Wang X, Zhao Y, Ji XS
Current biology : CB 2023 Dec 4;33(23):5057-5070.e5
Current biology : CB 2023 Dec 4;33(23):5057-5070.e5
Chemokine- and chemokine receptor-based signature predicts immunotherapy response in female colorectal adenocarcinoma patients.
Zhu W, Wu C, Hu S, Liu S, Zhao S, Zhang D, Qiu G, Cheng X, Huang J
Scientific reports 2023 Dec 4;13(1):21358
Scientific reports 2023 Dec 4;13(1):21358
Choline induced cardiac dysfunction by inhibiting the production of endogenous hydrogen sulfide in spontaneously hypertensive rats.
Zhang W, Zhang Y, Xia Y, Feng G, Wang Y, Wei C, Tang A, Song K, Qiu R, Wu Y, Jin S
Physiological research 2023 Dec 31;72(6):719-730
Physiological research 2023 Dec 31;72(6):719-730
Liver proteomics analysis reveals the differentiation of lipid mechanism and antioxidant enzyme activity during chicken embryonic development.
Shen N, Li C, Yang S, Ma Y, Wang HL
International journal of biological macromolecules 2023 Dec 31;253(Pt 7):127417
International journal of biological macromolecules 2023 Dec 31;253(Pt 7):127417
Selection of goat β-casein derived ACE-inhibitory peptide SQPK and insights into its effect and regulatory mechanism on the function of endothelial cells.
Wu Y, Zhang J, Mu T, Zhang H, Cao J, Li H, Tang H, Chen L, Liu H, Xu X, Zhao K
International journal of biological macromolecules 2023 Dec 31;253(Pt 6):127312
International journal of biological macromolecules 2023 Dec 31;253(Pt 6):127312
PRRSV alters m(6)A methylation and alternative splicing to regulate immune, extracellular matrix-associated function.
Lin C, Zeng M, Song J, Li H, Feng Z, Li K, Pei Y
International journal of biological macromolecules 2023 Dec 31;253(Pt 2):126741
International journal of biological macromolecules 2023 Dec 31;253(Pt 2):126741
NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA.
Li Z, Li D, Yang T, Yao C
Cancer biology & therapy 2023 Dec 31;24(1):2274143
Cancer biology & therapy 2023 Dec 31;24(1):2274143
MiR-128-1-5p inhibits cell proliferation and induces cell apoptosis via targeting PRKCQ in colorectal cancer.
Jia Q, Liao X, Xu B, Li Y, Liang L
Cancer biology & therapy 2023 Dec 31;24(1):2226421
Cancer biology & therapy 2023 Dec 31;24(1):2226421
CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma.
Han Y, Wang H, Chen H, Tan T, Wang Y, Yang H, Ding Y, Wang S
Cancer biology & therapy 2023 Dec 31;24(1):2221879
Cancer biology & therapy 2023 Dec 31;24(1):2221879
Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia.
Sun SL, Wu JZ, Wang JJ, Zhou H, Zhang CQ, Tong ZJ, Wang YB, Sha JK, Wang QX, Liu JC, Zheng XR, Li QQ, Zhang MY, Yang J, Wei TH, Wang ZX, Yu YC, Ding N, Leng XJ, Xue X, Li HM, Dai WC, Yin XY, Yang Y, Duan JA, Li NG, Shi ZH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115905
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115905
NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells.
Zhang C, Jiao B, Cao X, Zhang W, Yu S, Zhang K, Zhang M, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115889
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115889
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Chen Y, Yin H, Sun J, Zhang G, Zhang Y, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.
Huang P, Li H, Ren L, Xie H, Chen L, Liang Y, Hu Y, Selistre-de-Araujo HS, Boussios S, Jhawar SR, Cui R, Zuo Q, Chen Q
Translational cancer research 2023 Dec 31;12(12):3703-3717
Translational cancer research 2023 Dec 31;12(12):3703-3717
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy.
Cheng J, Yan Z, Jiang K, Liu C, Xu D, Lyu X, Hu X, Zhang S, Zhou Y, Li J, Zhao Y
Journal of medicinal chemistry 2023 Dec 28;66(24):16991-17025
Journal of medicinal chemistry 2023 Dec 28;66(24):16991-17025
Luteolin Alleviates Oxidative Stress in Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke via Modulation of the TRPV1 and CYP2A13/NRF2 Signaling Pathways.
Zhou L, Jian T, Wan Y, Huang R, Fang H, Wang Y, Liang C, Ding X, Chen J
International journal of molecular sciences 2023 Dec 27;25(1)
International journal of molecular sciences 2023 Dec 27;25(1)
FHL2 Inhibits SARS-CoV-2 Replication by Enhancing IFN-β Expression through Regulating IRF-3.
Xu Z, Tian M, Tan Q, Hao P, Gao Z, Li C, Jin N
International journal of molecular sciences 2023 Dec 26;25(1)
International journal of molecular sciences 2023 Dec 26;25(1)
Exosomal ITGB6 from dormant lung adenocarcinoma cells activates cancer-associated fibroblasts by KLF10 positive feedback loop and the TGF-β pathway.
Feng X, Liu X, Xiang J, Xu J, Yin N, Wang L, Liu C, Liu Y, Zhao T, Zhao Z, Gao Y
Translational lung cancer research 2023 Dec 26;12(12):2520-2537
Translational lung cancer research 2023 Dec 26;12(12):2520-2537
Mesenchymal stem cell exosomes inhibit nucleus pulposus cell apoptosis via the miR-125b-5p/TRAF6/NF-κB pathway axis.
Duan Y, Yu C, Kuang W, Li J, Qiu S, Ni S, Chen Z
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1938-1949
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1938-1949
Endometrial stromal cell autophagy-dependent ferroptosis caused by iron overload in ovarian endometriosis is inhibited by the ATF4-xCT pathway.
Dong X, Xu L, Wang S, Jiao X, Yan S, Huang Y, Yuan M, Wang G
Molecular human reproduction 2023 Dec 24;30(1)
Molecular human reproduction 2023 Dec 24;30(1)
FT895 Impairs Mitochondrial Function in Malignant Peripheral Nerve Sheath Tumor Cells.
Huang PY, Shih IA, Liao YC, You HL, Lee MJ
International journal of molecular sciences 2023 Dec 24;25(1)
International journal of molecular sciences 2023 Dec 24;25(1)
Autophagy-related 7 proteindependent autophagy mediates resveratrol-caused upregulation of mitochondrial biogenesis and steroidogenesis in aged Leydig cell.
Lin F, Zhang S, Zhu X, Lv Z
Molecular biology reports 2023 Dec 22;51(1):28
Molecular biology reports 2023 Dec 22;51(1):28
Linoleic acid: a natural feed compound against porcine epidemic diarrhea disease.
Yang S, Huang X, Li S, Wang C, Jansen CA, Savelkoul HFJ, Liu G
Journal of virology 2023 Dec 21;97(12):e0170023
Journal of virology 2023 Dec 21;97(12):e0170023
Circular RNA MTCL1 targets SMAD3 by sponging miR-145-5p for regulation of cell proliferation and migration in Hirschsprung's disease.
Chen W, Caiyun L, Yang Y, Xinwei H, Nan L, Jiaming Y, Huirong Y, Kai W, Liucheng Y
Pediatric surgery international 2023 Dec 21;40(1):25
Pediatric surgery international 2023 Dec 21;40(1):25
Experimental validation and pan-cancer analysis identified COL10A1 as a novel oncogene and potential therapeutic target in prostate cancer.
Xu S, Liu D, Qin Z, Liang Z, Xie H, Yi B, Wang K, Lin G, Liu R, Yang K, Xu Y, Zhang H
Aging 2023 Dec 21;15(24):15134-15160
Aging 2023 Dec 21;15(24):15134-15160
Novel Antioxidant Peptides Derived from Feather Keratin Alleviate H(2)O(2)-Induced Oxidative Damage in HepG2 Cells via Keap1/Nrf2 Pathway.
Pei XD, He YN, Wu QL, Zhang YM, Li F, Jiao DQ, Liu XL, Wang CH
Journal of agricultural and food chemistry 2023 Dec 20;71(50):20062-20072
Journal of agricultural and food chemistry 2023 Dec 20;71(50):20062-20072
[m(6)A methylase WTAP participates in renal ischemia-reperfusion injury by regulating FOXO1 expression].
Zhao G, Li H, Zhang H, Xiao K, Yang H, Li Z, Fu C
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Dec 20;43(12):2035-2042
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Dec 20;43(12):2035-2042
Integrated Amino Acids and Transcriptome Analysis Reveals Arginine Transporter SLC7A2 Is a Novel Regulator of Myogenic Differentiation.
Huang T, Zhou J, Wang B, Wang X, Xiao W, Yang M, Liu Y, Wang Q, Xiang Y, Lan X
International journal of molecular sciences 2023 Dec 20;25(1)
International journal of molecular sciences 2023 Dec 20;25(1)
ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway.
Chen J, Tang Y, Qin D, Yu X, Tong H, Tang C, Tang Z
Journal of translational medicine 2023 Dec 20;21(1):923
Journal of translational medicine 2023 Dec 20;21(1):923
Elevated FBXL6 activates both wild-type KRAS and mutant KRAS(G12D) and drives HCC tumorigenesis via the ERK/mTOR/PRELID2/ROS axis in mice.
Xiong HJ, Yu HQ, Zhang J, Fang L, Wu D, Lin XT, Xie CM
Military Medical Research 2023 Dec 20;10(1):68
Military Medical Research 2023 Dec 20;10(1):68
Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.
Ding Y, Li L, Wang S, Cao Y, Yang M, Dai Y, Lin H, Li J, Liu Y, Wang Z, Liu W, Tao J
Biological research 2023 Dec 2;56(1):65
Biological research 2023 Dec 2;56(1):65
Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation.
Dai B, Liu S, Shen W, Chen L, Zhou Q, Han L, Zhang Q, Shan L
Biological research 2023 Dec 2;56(1):64
Biological research 2023 Dec 2;56(1):64
Melatonin alleviates pyroptosis by regulating the SIRT3/FOXO3α/ROS axis and interacting with apoptosis in Atherosclerosis progression.
Cong L, Liu X, Bai Y, Qin Q, Zhao L, Shi Y, Bai Y, Guo Z
Biological research 2023 Dec 2;56(1):62
Biological research 2023 Dec 2;56(1):62
Predictive Roles of ADAM17 in Patient Survival and Immune Cell Infiltration in Hepatocellular Carcinoma.
Ding T, Yu Y, Gao L, Xiang L, Xu B, Gu B, Chen H
International journal of molecular sciences 2023 Dec 2;24(23)
International journal of molecular sciences 2023 Dec 2;24(23)
The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication.
Zhang S, Zeng L, Su B-Q, Yang G-Y, Wang J, Ming S-L, Chu B-B
mBio 2023 Dec 19;14(6):e0265123
mBio 2023 Dec 19;14(6):e0265123
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.
Cheng J, Wang Y, Yin L, Liang W, Zhang J, Ma C, Zhang Y, Liu B, Wang J, Zhao W, Li M, Wei L
mBio 2023 Dec 19;14(6):e0148023
mBio 2023 Dec 19;14(6):e0148023
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease.
Li C, Liu Q, Chang Q, Xie M, Weng J, Wang X, Li M, Chen J, Huang Y, Yang X, Wang K, Zhang N, Chung KF, Adcock IM, Zhang H, Li F
Respiratory research 2023 Dec 18;24(1):319
Respiratory research 2023 Dec 18;24(1):319
GETV nsP2 plays a critical role in the interferon antagonism and viral pathogenesis.
Mou C, Meng H, Shi K, Huang Y, Liu M, Chen Z
Cell communication and signaling : CCS 2023 Dec 18;21(1):361
Cell communication and signaling : CCS 2023 Dec 18;21(1):361
LLGL2 Inhibits Ovarian Cancer Metastasis by Regulating Cytoskeleton Remodeling via ACTN1.
Gu QY, Liu YX, Wang JL, Huang XL, Li RN, Linghu H
Cancers 2023 Dec 18;15(24)
Cancers 2023 Dec 18;15(24)
DDX5 Functions as a Tumor Suppressor in Tongue Cancer.
Liu Q, Sun Y, Long M, Chen X, Zhong S, Huang C, Wei R, Luo JL
Cancers 2023 Dec 18;15(24)
Cancers 2023 Dec 18;15(24)
α5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape.
Kang G, Jiao Y, Pan P, Fan H, Li Q, Li X, Li J, Wang Y, Jia Y, Wang J, Sun H, Ma X
Carcinogenesis 2023 Dec 15;44(10-11):773-784
Carcinogenesis 2023 Dec 15;44(10-11):773-784
Quercitrin attenuates the progression of osteoarthritis via inhibiting NF-κB signaling pathways and enhance glucose transport capacity.
Qiao S, Zhao R, He S, Fu X, An J, Xia T
Experimental cell research 2023 Dec 15;433(2):113854
Experimental cell research 2023 Dec 15;433(2):113854
Protocol for preparing Thiopropyl Sepharose resin used for capturing S-nitrosylated proteins.
Seth P, Hausladen A, Premont RT, Stamler JS
STAR protocols 2023 Dec 15;4(4):102430
STAR protocols 2023 Dec 15;4(4):102430
Profibrotic role of transcription factor SP1 in cross-talk between fibroblasts and M2 macrophages.
Feng P, Che Y, Gao C, Chu X, Li Z, Li L, Li J, Gao J, Dong Y
iScience 2023 Dec 15;26(12):108484
iScience 2023 Dec 15;26(12):108484
Perfluorooctanoic acid disrupts thyroid-specific genes expression and regulation via the TSH-TSHR signaling pathway in thyroid cells.
Du Y, Chen C, Zhou G, Cai Z, Man Q, Liu B, Wang WC
Environmental research 2023 Dec 15;239(Pt 1):117372
Environmental research 2023 Dec 15;239(Pt 1):117372
Transient receptor potential-related risk model predicts prognosis of hepatocellular carcinoma patients.
Mei XC, Chen Q, Zuo S
World journal of gastrointestinal oncology 2023 Dec 15;15(12):2064-2076
World journal of gastrointestinal oncology 2023 Dec 15;15(12):2064-2076
Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice.
Sun QY, Wang XY, Huang ZP, Song J, Zheng ED, Gong FH, Huang XW
World journal of diabetes 2023 Dec 15;14(12):1824-1838
World journal of diabetes 2023 Dec 15;14(12):1824-1838
Bioinformatics-based identification and validation of hub genes associated with aging in patients with coronary artery disease.
Zhang W, Zhao M, Xin L, Qi X, Cao P, Wang J, Li X
Aging 2023 Dec 14;15(24):14830-14844
Aging 2023 Dec 14;15(24):14830-14844
Different glycosylation profiles of cystatin F alter the cytotoxic potential of natural killer cells.
Senjor E, Pirro M, Švajger U, Prunk M, Sabotič J, Jewett A, Hensbergen PJ, Perišić Nanut M, Kos J
Cellular and molecular life sciences : CMLS 2023 Dec 13;81(1):8
Cellular and molecular life sciences : CMLS 2023 Dec 13;81(1):8
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
Jian Y, Zhang L, Gong L, Ding M, Sun X, Yu X, Lv S, Li J, Yang D, Wang S
Cancer cell international 2023 Dec 12;23(1):319
Cancer cell international 2023 Dec 12;23(1):319
Alpha-defensins inhibit ERK/STAT3 signaling during monocyte-macrophage differentiation and impede macrophage function.
Lee J, Mohammad N, Lu Y, Oshins R, Aranyos A, Brantly M
Respiratory research 2023 Dec 11;24(1):309
Respiratory research 2023 Dec 11;24(1):309
A positive feedback loop between ZEB2 and ACSL4 regulates lipid metabolism to promote breast cancer metastasis.
Lin J, Zhang P, Liu W, Liu G, Zhang J, Yan M, Duan Y, Yang N
eLife 2023 Dec 11;12
eLife 2023 Dec 11;12
MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression.
Sun Y, Jin X, Meng J, Guo F, Chen T, Zhao X, Wu H, Ren D
The EMBO journal 2023 Dec 1;42(23):e114558
The EMBO journal 2023 Dec 1;42(23):e114558
Neuropilin 1 promotes unilateral ureteral obstruction-induced renal fibrosis via RACK1 in renal tubular epithelial cells.
Hou L, Du Y
American journal of physiology. Renal physiology 2023 Dec 1;325(6):F870-F884
American journal of physiology. Renal physiology 2023 Dec 1;325(6):F870-F884
The linear ANRIL transcript P14AS regulates the NF-κB signaling to promote colon cancer progression.
Ma W, Hu J
Molecular medicine (Cambridge, Mass.) 2023 Dec 1;29(1):162
Molecular medicine (Cambridge, Mass.) 2023 Dec 1;29(1):162
Chlorin e6 (Ce6)-loaded plaque-specific liposome with enhanced photodynamic therapy effect for atherosclerosis treatment.
Zou L, Zhang Y, Cheraga N, Abodunrin OD, Qu KY, Qiao L, Ma YQ, Chen LJ, Huang NP
Talanta 2023 Dec 1;265:124772
Talanta 2023 Dec 1;265:124772
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
Wang L, Yu X, Li H, He D, Zeng S, Xiang Z
Chinese medicine 2023 Dec 1;18(1):158
Chinese medicine 2023 Dec 1;18(1):158
Mitophagy-dependent cardioprotection of resistance training on heart failure.
Guo C, Wu RY, Dou JH, Song SF, Sun XL, Hu YW, Guo FS, Wei J, Lin L, Wei J
Journal of applied physiology (Bethesda, Md. : 1985) 2023 Dec 1;135(6):1390-1401
Journal of applied physiology (Bethesda, Md. : 1985) 2023 Dec 1;135(6):1390-1401
CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.
Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, Zhou Y, Gao Q, Zhang L, Yan M, Sun Z, Fang D
The Journal of clinical investigation 2023 Dec 1;133(23)
The Journal of clinical investigation 2023 Dec 1;133(23)
Markerless bacterial artificial chromosome manipulation method by red proteins of phage λ mediated homologous recombination utilizing fluorescent proteins for both positive and counter selection.
Yoshikawa T, Misu M, Kurosu T, Takamatsu Y, Sugimoto S, Shimojima M, Ebihara H, Saijo M
Heliyon 2023 Aug;9(8):e18983
Heliyon 2023 Aug;9(8):e18983
Heterophyllin B ameliorates gastric cancer tumor growth through activating ER stress.
Xue W, Sun R, Hao Z, Xing Z, Cheng H, Shao L
Tissue & cell 2023 Aug;83:102129
Tissue & cell 2023 Aug;83:102129
Soluble dipeptidyl peptidase-4 induces epithelial-mesenchymal transition through tumor growth factor-β receptor.
Huang CW, Lee SY, Du CX, Ku HC
Pharmacological reports : PR 2023 Aug;75(4):1005-1016
Pharmacological reports : PR 2023 Aug;75(4):1005-1016
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning.
Shi F, de Fatima Silva F, Liu D, Patel HU, Xu J, Zhang W, Türk C, Krüger M, Collins S
Molecular metabolism 2023 Aug;74:101753
Molecular metabolism 2023 Aug;74:101753
Exosomal PPARγ derived from macrophages suppresses LPS-induced peritonitis by negative regulation of CD14/TLR4 axis.
Meng M, Lu M, Feng J, Zhou X, Meng P, Chen L, Zou X, Liu X, Liu L, Gao X, Zhang Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Aug;72(8):1567-1581
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Aug;72(8):1567-1581
Cyclic helix B peptide alleviates proinflammatory cell death and improves functional recovery after traumatic spinal cord injury.
Xu Y, Geng Y, Wang H, Zhang H, Qi J, Li F, Hu X, Chen Y, Si H, Li Y, Wang X, Xu H, Kong J, Cai Y, Wu A, Ni W, Xiao J, Zhou K
Redox biology 2023 Aug;64:102767
Redox biology 2023 Aug;64:102767
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
He Y, Zhang B, Han D, Du Y, Zhang X, Wang H, Yue Z, Shang P
Biochemical genetics 2023 Aug;61(4):1265-1281
Biochemical genetics 2023 Aug;61(4):1265-1281
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
Wang Z, Yang Z, Qu C, Li J, Wang X
International urology and nephrology 2023 Aug;55(8):1957-1970
International urology and nephrology 2023 Aug;55(8):1957-1970
Osmotic pressure induces translocation of aquaporin-8 by P38 and JNK MAPK signaling pathways in patients with functional constipation.
Lin C, He H, Kim JJ, Zheng X, Huang Z, Dai N
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1049-1059
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1049-1059
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
Shen C, Jiang Y, Lin J, He Y, Liu Y, Fang D
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
hsa_circ_0000417 downregulation suppresses androgen receptor expression and apoptotic signals in human foreskin fibroblasts via sponging miR-6756-5p.
Huang J, Su C, Lu P, Zhao X, Liu Y, Xie Q, Chen C
Molecular biology reports 2023 Aug;50(8):6769-6781
Molecular biology reports 2023 Aug;50(8):6769-6781
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Zhong B, Zhu Q, Wang L, Wang F, Zheng Y, Lin S, Cheng X
Cell biology international 2023 Aug;47(8):1368-1380
Cell biology international 2023 Aug;47(8):1368-1380
JMJD3 ablation in myeloid cells confers renoprotection in mice with DOCA/salt-induced hypertension.
Gao Y, Yu W, Song J, Nie J, Cui Z, Wen S, Liu B, Liang H
Hypertension research : official journal of the Japanese Society of Hypertension 2023 Aug;46(8):1934-1948
Hypertension research : official journal of the Japanese Society of Hypertension 2023 Aug;46(8):1934-1948
Brain-targeted lycopene-loaded microemulsion modulates neuroinflammation, oxidative stress, apoptosis and synaptic plasticity in β-amyloid-induced Alzheimer's disease mice.
Guo Y, Fan Z, Zhao S, Yu W, Hou X, Nie S, Xu S, Zhao C, Han J, Liu X
Neurological research 2023 Aug;45(8):753-764
Neurological research 2023 Aug;45(8):753-764
AMP-activated protein kinase-farnesoid X receptor pathway contributes to oleanolic acid-induced liver injury.
Huang J, Liao S, Fu X, Wang Y, Zhou S, Lu Y
Journal of applied toxicology : JAT 2023 Aug;43(8):1201-1213
Journal of applied toxicology : JAT 2023 Aug;43(8):1201-1213
An early-onset SLE patient with a novel paternal inherited BACH2 mutation.
Zhou L, Sun G, Chen R, Chen J, Fang S, Xu Q, Tang W, Dai R, Zhang Z, An Y, Tang X, Zhao X
Journal of clinical immunology 2023 Aug;43(6):1367-1378
Journal of clinical immunology 2023 Aug;43(6):1367-1378
Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS-mediated mitochondrial pathway.
Chen Y, Zhang Y, Wang X, Qiao S
Journal of biochemical and molecular toxicology 2023 Aug;37(8):e23387
Journal of biochemical and molecular toxicology 2023 Aug;37(8):e23387
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Zhang ZT, Deng SM, Chen C, He QH, Peng XW, Liang QF, Zhuang GD, Wang SM, Tang D
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
He P, He Y, Ma J, Liu Y, Liu C, Baoping Y, Dong W
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
Mulberry leaf water extract alleviates type 2 diabetes in mice via modulating gut microbiota-host co-metabolism of branched-chain amino acid.
Zheng XX, Li DX, Li YT, Chen YL, Zhao YL, Ji S, Guo MZ, Du Y, Tang DQ
Phytotherapy research : PTR 2023 Aug;37(8):3195-3210
Phytotherapy research : PTR 2023 Aug;37(8):3195-3210
Withdrawal: CircKIAA1429 accelerates hepatocellular carcinoma advancement by miR-199b-5p/OTX1 pathway, by Bin Lu, Min Cheng, Tao Wang.
Journal of viral hepatitis 2023 Aug;30(8):713
A MAPK signaling cascade regulates the fusaric acid-induced cell death in Arabidopsis.
Xiao Z, Huang G, Lu D
Journal of plant physiology 2023 Aug;287:154049
Journal of plant physiology 2023 Aug;287:154049
Complement factor H inhibits endothelial cell migration through suppression of STAT3 signaling.
Li J, Huang H, Xu S, Fan M, Wang K, Wang X, Zhang J, Huang S, Gatt A, Liu J
Experimental and therapeutic medicine 2023 Aug;26(2):408
Experimental and therapeutic medicine 2023 Aug;26(2):408
SUV39H1 is a prognosis and immune microenvironment-related biomarker in diffuse large B-cell lymphoma.
Zhang Y, Qian S, Wen Q, Lei Y, Ge J, Kong X, Wang W, Wang Z, Hou H, Tang C, Wu S, Wang G, Li W, Zhang M, Zhang X, Chen Q
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Aug;25(8):2438-2450
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Aug;25(8):2438-2450
SOX9/NFIA promotes human ovarian cancer metastasis through the Wnt/β-catenin signaling pathway.
Lu R, Tang P, Zhang D, Lin S, Li H, Feng X, Sun M, Zhang H
Pathology, research and practice 2023 Aug;248:154602
Pathology, research and practice 2023 Aug;248:154602
Complement C3a receptor antagonist alleviates tau pathology and ameliorates cognitive deficits in P301S mice.
Yao Y, Chang Y, Li S, Zhu J, Wu Y, Jiang X, Li L, Liu R, Ma R, Li G
Brain research bulletin 2023 Aug;200:110685
Brain research bulletin 2023 Aug;200:110685
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations.
Ou J, Lewandowski EM, Hu Y, Lipinski AA, Aljasser A, Colon-Ascanio M, Morgan RT, Jacobs LMC, Zhang X, Bikowitz MJ, Langlais PR, Tan H, Wang J, Chen Y, Choy JS
PLoS pathogens 2023 Aug;19(8):e1011592
PLoS pathogens 2023 Aug;19(8):e1011592
EIF4A3-Induced Exosomal circLRRC8A Alleviates Granulosa Cells Senescence Via the miR-125a-3p/NFE2L1 axis.
Xing J, Zhang M, Zhao S, Lu M, Lin L, Chen L, Gao W, Li W, Shang J, Zhou J, Zhu X
Stem cell reviews and reports 2023 Aug;19(6):1994-2012
Stem cell reviews and reports 2023 Aug;19(6):1994-2012
Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice.
Yang LX, Yao YY, Yang JR, Cheng HL, Zhu XJ, Zhang ZJ
Neural regeneration research 2023 Aug;18(8):1763-1769
Neural regeneration research 2023 Aug;18(8):1763-1769
Piezo1 suppression reduces demyelination after intracerebral hemorrhage.
Qu J, Zong HF, Shan Y, Zhang SC, Guan WP, Yang Y, Zhao HL
Neural regeneration research 2023 Aug;18(8):1750-1756
Neural regeneration research 2023 Aug;18(8):1750-1756
Inhibition of CDCP1 by 8-isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment.
Wong SC, Yeh CC, Zhang XY, Hsieh CY, Lo CC, Kuo TT, Lin CC, Chao CH, Liu JP, Chang LC, Wang LH, Sher YP
Molecular oncology 2023 Aug;17(8):1648-1665
Molecular oncology 2023 Aug;17(8):1648-1665
p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis.
Ye Z, Xia Y, Li L, Li B, Chen L, Yu W, Ruan Y, Rao T, Zhou X, Cheng F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114925
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114925
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
Feng DD, Chen JH, Chen YF, Cao Q, Li BJ, Chen XQ, Jin R, Zhou GP
Molecular immunology 2023 Aug;160:67-79
Molecular immunology 2023 Aug;160:67-79
Emerging glyco-risk prediction model to forecast response to immune checkpoint inhibitors in colorectal cancer.
Qiu P, Chen X, Xiao C, Zhang M, Wang H, Wang C, Li D, Liu J, Chen Y, Liu L, Zhao Q
Journal of cancer research and clinical oncology 2023 Aug;149(9):6411-6434
Journal of cancer research and clinical oncology 2023 Aug;149(9):6411-6434
HPV18 E6 inhibits α-ketoglutarate-induced pyroptosis of esophageal squamous cell carcinoma cells via the P53/MDH1/ROS/GSDMC pathway.
Tang D, Zheng Y, Wang G, Sheng C, Liu Z, Wang B, Zong Q, Zhang Y, Hou X, Yao M, Zhou Z
FEBS open bio 2023 Aug;13(8):1522-1535
FEBS open bio 2023 Aug;13(8):1522-1535
Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin.
Gao F, Feng Y, Hu X, Zhang X, Li T, Wang Y, Ge S, Wang C, Chi J, Tan X, Wang N
International immunopharmacology 2023 Aug;121:110540
International immunopharmacology 2023 Aug;121:110540
The ALOX5 inhibitor Zileuton regulates tumor-associated macrophage M2 polarization by JAK/STAT and inhibits pancreatic cancer invasion and metastasis.
Hu WM, Liu SQ, Zhu KF, Li W, Yang ZJ, Yang Q, Zhu ZC, Chang J
International immunopharmacology 2023 Aug;121:110505
International immunopharmacology 2023 Aug;121:110505
GKLF, a transcriptional activator of Txnip, drives microglia activation in kainic acid-induced murine models of epileptic seizures.
Zhuo Z, Wang Y, Kong H, Fu T
International immunopharmacology 2023 Aug;121:110426
International immunopharmacology 2023 Aug;121:110426
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
Dai H, Wu R, Zhang J, Dou R, Xu M, Wang J, Wang J, Su F, Zhang T
Cancer medicine 2023 Aug;12(16):17212-17222
Cancer medicine 2023 Aug;12(16):17212-17222
Ketogenic diet alleviates renal interstitial fibrosis in UUO mice by regulating macrophage proliferation.
Hu X, Qiu Y, Cao R, Xu C, Lu C, Wang Z, Yang J
The Journal of nutritional biochemistry 2023 Aug;118:109335
The Journal of nutritional biochemistry 2023 Aug;118:109335
Low androgen levels induce ferroptosis of rat penile cavernous endothelial cells.
Shi HX, Zhao X, Yang H, Cheng Y, Jiang J, Jiang R
Sexual medicine 2023 Aug;11(4):qfad043
Sexual medicine 2023 Aug;11(4):qfad043
DNA methylation of RUNX3 promotes the progression of gallbladder cancer through repressing SLC7A11-mediated ferroptosis.
Cai C, Zhu Y, Mu J, Liu S, Yang Z, Wu Z, Zhao C, Song X, Ye Y, Gu J, Sang Y, Wu X, Gong W
Cellular signalling 2023 Aug;108:110710
Cellular signalling 2023 Aug;108:110710
Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway.
Li Y, Zhang ZH, Huang SL, Yue ZB, Yin XS, Feng ZQ, Zhang XG, Song GL
Journal of dairy science 2023 Aug;106(8):5253-5265
Journal of dairy science 2023 Aug;106(8):5253-5265
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Wang Y, Hu Y, Lan S, Chen Z, Zhang Y, Guo X, Cai L, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration.
Zhong L, Sheng X, Wang W, Li Y, Zhuo R, Wang K, Zhang L, Hu DD, Hong Y, Chen L, Rao H, Li T, Chen M, Lin Z, Zhang YW, Wang X, Yan XX, Chen X, Bu G, Chen XF
Immunity 2023 Aug 8;56(8):1794-1808.e8
Immunity 2023 Aug 8;56(8):1794-1808.e8
Loss of N-acetylglucosaminyl transferase V is involved in the impaired osteogenic differentiation of bone marrow mesenchymal stem cells.
Liu XP, Li JQ, Li RY, Cao GL, Feng YB, Zhang W
Experimental animals 2023 Aug 7;72(3):413-424
Experimental animals 2023 Aug 7;72(3):413-424
Expression and localization of α(2A)-adrenergic receptor in the rat post-natal developing cochlea.
Tian C, Yang Y, Li Y, Sun F, Qu J, Zha D
European journal of histochemistry : EJH 2023 Aug 7;67(3)
European journal of histochemistry : EJH 2023 Aug 7;67(3)
DKK1-targeting cholesterol-modified siRNA implication in hair growth regulation.
Papukashvili D, Liu C, Rcheulishvili N, Xie F, Wang X, Feng S, Sun X, Zhang C, Li Y, He Y, Wang PG
Biochemical and biophysical research communications 2023 Aug 6;668:55-61
Biochemical and biophysical research communications 2023 Aug 6;668:55-61
Inhibit ALDH3A2 reduce ovarian cancer cells survival via elevating ferroptosis sensitivity.
Dong H, He L, Sun Q, Zhan J, Li J, Xiong X, Zhuang L, Wu S, Li Y, Yin C, He Q
Gene 2023 Aug 5;876:147515
Gene 2023 Aug 5;876:147515
Inhibition of human adenovirus replication by TRIM35-mediated degradation of E1A.
Sun N, Zhang J, Zhang C, Xie T, Zhang Z, Wang X, Li W, Zhang Y, Chen Z, Zheng J, Fang L, Wang G
Journal of virology 2023 Aug 31;97(8):e0070023
Journal of virology 2023 Aug 31;97(8):e0070023
Salidroside Supplementation Affects In Vitro Maturation and Preimplantation Embryonic Development by Promoting Meiotic Resumption.
Shi S, Geng Z, Yu X, Hu B, Liu L, Chi Z, Qu L, Zhang M, Jin Y
Genes 2023 Aug 30;14(9)
Genes 2023 Aug 30;14(9)
Exploring the Therapeutic Potential of Ethyl 3-Hydroxybutyrate in Alleviating Skeletal Muscle Wasting in Cancer Cachexia.
Zhou Y, Lu R, Lin F, Chen S, He QQ, Wu G, Huang C, Lin D
Biomolecules 2023 Aug 30;13(9)
Biomolecules 2023 Aug 30;13(9)
The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis.
Shi T, Liu T, Kou Y, Rong X, Meng L, Cui Y, Gao R, Hu S, Li M
Medicina (Kaunas, Lithuania) 2023 Aug 3;59(8)
Medicina (Kaunas, Lithuania) 2023 Aug 3;59(8)
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal.
Li Y, Xue M, Deng X, Dong L, Nguyen LXT, Ren L, Han L, Li C, Xue J, Zhao Z, Li W, Qing Y, Shen C, Tan B, Chen Z, Leung K, Wang K, Swaminathan S, Li L, Wunderlich M, Mulloy JC, Li X, Chen H, Zhang B, Horne D, Rosen ST, Marcucci G, Xu M, Li Z, Wei M, Tian J, Shen B, Su R, Chen J
Cell stem cell 2023 Aug 3;30(8):1072-1090.e10
Cell stem cell 2023 Aug 3;30(8):1072-1090.e10
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner.
Shi M, Hou J, Liang W, Li Q, Shao S, Ci S, Shu C, Zhao X, Zhao S, Huang M, Wu C, Hu Z, He L, Guo Z, Pan F
EMBO reports 2023 Aug 3;24(8):e56437
EMBO reports 2023 Aug 3;24(8):e56437
METTL3-mediated m6A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial-mesenchymal transition.
Wang Y, Chen Y, Liang J, Jiang M, Zhang T, Wan X, Wu J, Li X, Chen J, Sun J, Hu Y, Huang P, Feng J, Liu T, Sun X
Journal of molecular cell biology 2023 Aug 3;15(3)
Journal of molecular cell biology 2023 Aug 3;15(3)
Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia.
Tworak A, Kolesnikov AV, Hong JD, Choi EH, Luu JC, Palczewska G, Dong Z, Lewandowski D, Brooks MJ, Campello L, Swaroop A, Kiser PD, Kefalov VJ, Palczewski K
Cell reports 2023 Aug 29;42(8):112982
Cell reports 2023 Aug 29;42(8):112982
Subcellular localization shapes the fate of RNA polymerase III.
Tian K, Wang R, Huang J, Wang H, Ji X
Cell reports 2023 Aug 29;42(8):112941
Cell reports 2023 Aug 29;42(8):112941
Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome.
Ge J, Wang Y, Chen X, Yu K, Luo ZQ, Liu X, Qiu J
Cell reports 2023 Aug 29;42(8):112817
Cell reports 2023 Aug 29;42(8):112817
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Yue L, Xu X, Dai S, Xu F, Zhao W, Gu J, Dai X, Qian X
Scientific reports 2023 Aug 28;13(1):14092
Scientific reports 2023 Aug 28;13(1):14092
MiR-297 inhibits tumour progression of liver cancer by targeting PTBP3.
Lu N, Min J, Peng L, Huang S, Chai X, Wang S, Wang J
Cell death & disease 2023 Aug 26;14(8):564
Cell death & disease 2023 Aug 26;14(8):564
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp.
Xu YC, Zheng H, Guo JC, Tan XY, Zhao T, Song YF, Wei XL, Luo Z
Antioxidants (Basel, Switzerland) 2023 Aug 23;12(9)
Antioxidants (Basel, Switzerland) 2023 Aug 23;12(9)
METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway.
Xu M, Yu J, Liu X, Jia W, Duan Y, Ma D, Ma J, Lei W, Tai W
Medical oncology (Northwood, London, England) 2023 Aug 22;40(9):274
Medical oncology (Northwood, London, England) 2023 Aug 22;40(9):274
Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis.
Xiong H, Ren S, Chen J, Yang X, Liu Y, Xu Z, Guo J, Jiang T, Yuan M, Liu Y, Zhang G, Li W, Machens HG, Chen Z
Stem cell research & therapy 2023 Aug 21;14(1):213
Stem cell research & therapy 2023 Aug 21;14(1):213
Circ_0000235 targets MCT4 to promote glycolysis and progression of bladder cancer by sponging miR-330-5p.
Zhong J, Xu A, Xu P, Su M, Wang P, Liu Z, Li B, Liu C, Jiang N
Cell death discovery 2023 Aug 2;9(1):283
Cell death discovery 2023 Aug 2;9(1):283
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Liu X, Li J, Yang X, Li X, Kong J, Qi D, Zhang F, Sun B, Liu Y, Liu T
International journal of oral science 2023 Aug 2;15(1):32
International journal of oral science 2023 Aug 2;15(1):32
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
Li MX, Wu XT, Jing WQ, Hou WK, Hu S, Yan W
Cell death & disease 2023 Aug 2;14(8):492
Cell death & disease 2023 Aug 2;14(8):492
[Characteristics and microRNA expression profile of exosomes derived from odontogenic dental pulp stem cells].
Ye YY, Yue L, Zou XY, Wang XY
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2023 Aug 18;55(4):689-696
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2023 Aug 18;55(4):689-696
Sinomenine alleviates lipopolysaccharide-induced acute lung injury via a PPARβ/δ-dependent mechanism.
Zhao L, Zhang M, Liu YW, Tan Y, Yin J, Chen Y, Chen D, Ni B
European journal of pharmacology 2023 Aug 15;953:175838
European journal of pharmacology 2023 Aug 15;953:175838
The mitochondrial-derived peptide MOTS-c suppresses ferroptosis and alleviates acute lung injury induced by myocardial ischemia reperfusion via PPARγ signaling pathway.
Lu P, Li X, Li B, Li X, Wang C, Liu Z, Ji Y, Wang X, Wen Z, Fan J, Yi C, Song M, Wang X
European journal of pharmacology 2023 Aug 15;953:175835
European journal of pharmacology 2023 Aug 15;953:175835
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
linc01515 regulates PM(2.5)-induced oxidative stress via targeting NRF2 in airway epithelial cells.
Wang X, Zhu H, Sun G, Zhou M, Zhang H, Liu H, Wang M, Zhang Z, Chu H
Environmental pollution (Barking, Essex : 1987) 2023 Aug 15;331(Pt 2):121798
Environmental pollution (Barking, Essex : 1987) 2023 Aug 15;331(Pt 2):121798
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y
Journal of translational medicine 2023 Aug 14;21(1):544
Journal of translational medicine 2023 Aug 14;21(1):544
Mitochondrial protein MPV17 promotes β-cell apoptosis in diabetogenesis.
Tang Q, Shi W, Liu M, Tang L, Ren W, Shi S
Clinical science (London, England : 1979) 2023 Aug 14;137(15):1195-1208
Clinical science (London, England : 1979) 2023 Aug 14;137(15):1195-1208
Anthraquinone metabolites isolated from the rhizosphere soil Streptomyces of Panax notoginseng (Burk.) F. H. Chen target MMP2 to inhibit cancer cell migration.
Xue JY, Wu YY, Han YL, Song XY, Zhang MY, Cheng J, Lin B, Xia MY, Zhang YX
Journal of ethnopharmacology 2023 Aug 10;312:116457
Journal of ethnopharmacology 2023 Aug 10;312:116457
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Zhou M, Gao Y, Wu S, Chen J, Ding J, Wang Y, Yang J
Biology of reproduction 2023 Aug 10;109(2):204-214
Biology of reproduction 2023 Aug 10;109(2):204-214
USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein.
Shi S, Pan X, Chen M, Zhang L, Zhang S, Wang X, Shi S, Chen Z, Lin W, Jiang Y
Hepatology communications 2023 Aug 1;7(8)
Hepatology communications 2023 Aug 1;7(8)
Molecular mechanism of kidney damage caused by abamectin in carp: Oxidative stress, inflammation, mitochondrial damage, and apoptosis.
Wu X, Ma Y, Li X, He N, Zhang T, Liu F, Feng H, Dong J
Toxicology 2023 Aug 1;494:153599
Toxicology 2023 Aug 1;494:153599
TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling.
Xu T, Yang Y, Chen Z, Wang J, Wang X, Zheng Y, Wang C, Wang Y, Zhu Z, Ding X, Zhou J, Li G, Zhang H, Zhang W, Wu Y, Song X
Journal of experimental & clinical cancer research : CR 2023 Aug 1;42(1):190
Journal of experimental & clinical cancer research : CR 2023 Aug 1;42(1):190
Ruxolitinib Alleviates Inflammation, Apoptosis, and Intestinal Barrier Leakage in Ulcerative Colitis via STAT3.
Li C, Xu Y, Gao T, Zhang S, Lin Z, Gu S, Fang Y, Yuan X, Yu S, Jiang Q, Lou Z, Zhang X, Zhang J, Wu Q, Gu M, Ding X, Sun J, Chen Y
Inflammatory bowel diseases 2023 Aug 1;29(8):1191-1201
Inflammatory bowel diseases 2023 Aug 1;29(8):1191-1201
Overlaid Transcriptional and Proteome Analyses Identify Mitotic Kinesins as Important Targets of Arylsulfonamide-Mediated RBM39 Degradation.
Coomar S, Mota P, Penson A, Schwaller J, Abdel-Wahab O, Gillingham D
Molecular cancer research : MCR 2023 Aug 1;21(8):768-778
Molecular cancer research : MCR 2023 Aug 1;21(8):768-778
MTHFD1 is critical for the negative regulation of retinoic acid receptor signalling in anencephaly.
Xie X, Li C, Yu J, Chang S, Cheng X, Wang F, Bao Y, Zhang T, Wang S
Brain : a journal of neurology 2023 Aug 1;146(8):3455-3469
Brain : a journal of neurology 2023 Aug 1;146(8):3455-3469
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Zheng Y, Zhan Y, Zhang Y, Zhang Y, Liu Y, Xie Y, Sun Y, Qian J, Ding Y, Ding Y, Fang Y
Cell death & disease 2023 Aug 1;14(8):488
Cell death & disease 2023 Aug 1;14(8):488
Houpo paiqi mixture promotes intestinal motility in constipated rats by modulating gut microbiota and activating 5-HT-cAMP-PKA signal pathway.
Wang R, Lu X, Zhao L, Zhang W, Zhang S
Journal of applied microbiology 2023 Aug 1;134(8)
Journal of applied microbiology 2023 Aug 1;134(8)
rhMYDGF Alleviates I/R-induced Kidney Injury by Inhibiting Inflammation and Apoptosis via the Akt Pathway.
Wang J, Ma R, Wang Y, Zhang S, Wang J, Zheng J, Xue W, Ding X
Transplantation 2023 Aug 1;107(8):1729-1739
Transplantation 2023 Aug 1;107(8):1729-1739
An active fraction from Spatholobus suberectus dunn inhibits the inflammatory response by regulating microglia activation, switching microglia polarization from M1 to M2 and suppressing the TLR4/MyD88/NF-κB pathway in LPS-stimulated BV2 cells.
Ban M, Su H, Zeng X, Chen C, Zhou S, Chen X, Nong Z
Heliyon 2023 Apr;9(4):e14979
Heliyon 2023 Apr;9(4):e14979
Corticostriatal Projections Relying on GABA Levels Mediate Exercise-Induced Functional Recovery in Cerebral Ischemic Mice.
Xing Y, Zhang A, Li C, Han J, Wang J, Luo L, Chang X, Tian Z, Bai Y
Molecular neurobiology 2023 Apr;60(4):1836-1853
Molecular neurobiology 2023 Apr;60(4):1836-1853
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
Wang S, Liu J, Cheng D, Ren L, Zheng L, Chen F, Zeng T
Toxicology 2023 Apr;488:153487
Toxicology 2023 Apr;488:153487
Molecular docking and in vitro experiments verified that kaempferol induced apoptosis and inhibited human HepG2 cell proliferation by targeting BAX, CDK1, and JUN.
Zhang Q, Chen L, Gao M, Wang S, Meng L, Guo L
Molecular and cellular biochemistry 2023 Apr;478(4):767-780
Molecular and cellular biochemistry 2023 Apr;478(4):767-780
Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer.
Liu C, Wang X, Qin W, Tu J, Li C, Zhao W, Ma L, Liu B, Qiu H, Yuan X
Cancer communications (London, England) 2023 Apr;43(4):435-454
Cancer communications (London, England) 2023 Apr;43(4):435-454
Inhibiting PAC1 receptor internalization and endosomal ERK pathway activation may ameliorate hyperalgesia in a chronic migraine rat model.
Zhang L, Zhou Y, Wang Y, Yang L, Wang Y, Shan Z, Liang J, Xiao Z
Cephalalgia : an international journal of headache 2023 Apr;43(4):3331024231163131
Cephalalgia : an international journal of headache 2023 Apr;43(4):3331024231163131
C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis.
Huang S, Li J, Wu S, Zheng Z, Wang C, Li H, Zhao L, Zhang X, Huang H, Huang C, Xie Q
Oncogene 2023 Apr;42(17):1333-1346
Oncogene 2023 Apr;42(17):1333-1346
L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis.
Tabata S, Kojima Y, Sakamoto T, Igarashi K, Umetsu K, Ishikawa T, Hirayama A, Kajino-Sakamoto R, Sakamoto N, Yasumoto KI, Okano K, Suzuki Y, Yachida S, Aoki M, Soga T
Oncogene 2023 Apr;42(16):1294-1307
Oncogene 2023 Apr;42(16):1294-1307
Inhibition of autophagic flux by the curcumin analog EF-24 and its antiproliferative effect on MCF-7 cancer cells.
Li J, Wang SH, Liu YT, Zhang Q, Zhou GZ
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23307
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23307
CEBPB upregulates P4HA2 to promote the malignant biological behavior in IDH1 wildtype glioma.
Wang S, Wu J, Zhao W, Li M, Li S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22848
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22848
LINC01232 promotes lung squamous cell carcinoma progression through modulating miR-181a-5p/SMAD2 axis.
Zhang D, Hua M, Zhang N
The American journal of the medical sciences 2023 Apr;365(4):386-395
The American journal of the medical sciences 2023 Apr;365(4):386-395
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos.
Zhuang J, Pan ZJ, Qin Y, Liang H, Zhang WF, Sun ZY, Shi HB
Environmental science and pollution research international 2023 Apr;30(18):54022-54034
Environmental science and pollution research international 2023 Apr;30(18):54022-54034
Integrative Analysis of ceRNA Networks in human periodontal ligament stem cells under hypoxia.
Ye Y, Fu L, Liu L, Xiao T, Cuba Manduca AG, Yu J
Oral diseases 2023 Apr;29(3):1197-1213
Oral diseases 2023 Apr;29(3):1197-1213
The enzymatic hydrolysate of fucoidan from Sargassum hemiphyllum triggers immunity in plants.
Wang R, Bai J, Yan G, Xiao Z, Chen K, Li K, Tang J, Lu D
Journal of plant physiology 2023 Apr;283:153967
Journal of plant physiology 2023 Apr;283:153967
Transcriptomic analysis of the effects of the HPV18 E6E7 gene on the cell death mode in esophageal squamous cell carcinoma.
Tang D, Wang G, Liu Z, Wang B, Yao M, Wang Q, Hou X, Zheng Y, Sheng C, Zhou Z
Oncology letters 2023 Apr;25(4):167
Oncology letters 2023 Apr;25(4):167
CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.
Zhu Y, Zuo L, Xiong H, Li S, Chen R, Liu H
Cell cycle (Georgetown, Tex.) 2023 Apr;22(8):919-938
Cell cycle (Georgetown, Tex.) 2023 Apr;22(8):919-938
CMPK2 restricts Zika virus replication by inhibiting viral translation.
Pawlak JB, Hsu JC, Xia H, Han P, Suh HW, Grove TL, Morrison J, Shi PY, Cresswell P, Laurent-Rolle M
PLoS pathogens 2023 Apr;19(4):e1011286
PLoS pathogens 2023 Apr;19(4):e1011286
Epiberberine regulates lipid synthesis through SHP (NR0B2) to improve non-alcoholic steatohepatitis.
Zhou LM, Fan JH, Xu MM, Xiong MY, Wang QJ, Chai X, Li XD, Li XG, Ye XL
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166639
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166639
Poly-L-ornithine blocks the inhibitory effects of fibronectin on oligodendrocyte differentiation and promotes myelin repair.
Xiong YJ, Soomro SH, Huang ZH, Yu PP, Ping J, Fu H
Neural regeneration research 2023 Apr;18(4):832-839
Neural regeneration research 2023 Apr;18(4):832-839
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
Cui X, Yun X, Sun M, Li R, Lyu X, Lao Y, Qin X, Yu W
Hepatology international 2023 Apr;17(2):377-392
Hepatology international 2023 Apr;17(2):377-392
lncR-GAS5 upregulates the splicing factor SRSF10 to impair endothelial autophagy, leading to atherogenesis.
Fan Y, Zhang Y, Zhao H, Liu W, Xu W, Jiang L, Xu R, Zheng Y, Tang X, Li X, Zhao L, Liu X, Hong Y, Lin Y, Chen H, Zhang Y
Frontiers of medicine 2023 Apr;17(2):317-329
Frontiers of medicine 2023 Apr;17(2):317-329
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma.
Chen R, Wang Z, Lu T, Liu Y, Ji Y, Yu Y, Tou F, Guo S
Thoracic cancer 2023 Apr;14(10):893-912
Thoracic cancer 2023 Apr;14(10):893-912
Dysregulation of alternative splicing contributes to multiple myeloma pathogenesis.
Song S, Zhang W, Li Q, Wang Z, Su Q, Zhang X, Li B, Zhuang W
British journal of cancer 2023 Apr;128(6):1086-1094
British journal of cancer 2023 Apr;128(6):1086-1094
Recombinant human p53 adenovirus injection combined with Bortezomib inhibits proliferation and promotes apoptosis in multiple myeloma.
Wang Q, Shi Q, Chen Y, Wang G, Shen L
Leukemia research 2023 Apr;127:107041
Leukemia research 2023 Apr;127:107041
TPX2 promotes ovarian tumorigenesis by interacting with Lamin A/C and affecting its stability.
Meng X, Cao J, Zheng H, Ma X, Wang Y, Tong Y, Xie S, Lu R, Guo L
Cancer medicine 2023 Apr;12(8):9738-9748
Cancer medicine 2023 Apr;12(8):9738-9748
IGFL2-AS1-induced suppression of HIF-1α degradation promotes cell proliferation and invasion in colorectal cancer by upregulating CA9.
Qin M, Liu Q, Yang W, Wang Q, Xiang Z
Cancer medicine 2023 Apr;12(7):8415-8432
Cancer medicine 2023 Apr;12(7):8415-8432
Lithium-Containing Biomaterials Stimulate Cartilage Repair through Bone Marrow Stromal Cells-Derived Exosomal miR-455-3p and Histone H3 Acetylation.
Liu L, Yu F, Chen L, Xia L, Wu C, Fang B
Advanced healthcare materials 2023 Apr;12(11):e2202390
Advanced healthcare materials 2023 Apr;12(11):e2202390
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Dong C, Song C, He Z, Song Q, Song T, Liu J, Xiong Y, Su X, Zhou J, Yang S, Liao W
International immunopharmacology 2023 Apr;117:110042
International immunopharmacology 2023 Apr;117:110042
Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats.
Mu G, Li Q, Lu B, Yu X
International immunopharmacology 2023 Apr;117:110033
International immunopharmacology 2023 Apr;117:110033
The cGAS-STING pathway promotes endometriosis by up-regulating autophagy.
Zhu S, Chen Q, Sun J, Du W, Chen Z, Yu M, Tao J, Zhou Y, Zhao Y, Zhang Q
International immunopharmacology 2023 Apr;117:109644
International immunopharmacology 2023 Apr;117:109644
Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma.
Zhang Z, Shi Y, Zhu Z, Fu J, Liu D, Liu X, Dang J, Tao H, Fan H
Cancer science 2023 Apr;114(4):1240-1255
Cancer science 2023 Apr;114(4):1240-1255
Iron-frataxin involved in the protective effect of quercetin against alcohol-induced liver mitochondrial dysfunction.
Liu J, Chen H, Lin H, Peng S, Chen L, Cheng X, Yao P, Tang Y
The Journal of nutritional biochemistry 2023 Apr;114:109258
The Journal of nutritional biochemistry 2023 Apr;114:109258
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Chen S, Lu K, Hou Y, You Z, Shu C, Wei X, Wu T, Shi N, Zhang G, Wu J, Chen S, Zhang L, Li W, Zhang D, Ju S, Chen M, Xu B
Journal for immunotherapy of cancer 2023 Apr;11(4)
Journal for immunotherapy of cancer 2023 Apr;11(4)
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Zhang Q, Liu S, Wang H, Xiao K, Lu J, Chen S, Huang M, Xie R, Lin T, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
PRPF19 facilitates colorectal cancer liver metastasis through activation of the Src-YAP1 pathway via K63-linked ubiquitination of MYL9.
Zhou R, Chen J, Xu Y, Ye Y, Zhong G, Chen T, Qiu L
Cell death & disease 2023 Apr 8;14(4):258
Cell death & disease 2023 Apr 8;14(4):258
Acetylcholine promotes chronic stress-induced lung adenocarcinoma progression via α5-nAChR/FHIT pathway.
Jiao Y, Kang G, Pan P, Fan H, Li Q, Li X, Li J, Wang Y, Jia Y, Zhang L, Sun H, Ma X
Cellular and molecular life sciences : CMLS 2023 Apr 7;80(5):119
Cellular and molecular life sciences : CMLS 2023 Apr 7;80(5):119
Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy.
Tan HY, Liang FM, Zhang WJ, Zhang Y, Cui JH, Dai YY, Qiu XM, Wang WH, Zhou Y, Chen DP, Li CP
Molecules (Basel, Switzerland) 2023 Apr 7;28(8)
Molecules (Basel, Switzerland) 2023 Apr 7;28(8)
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Gao X, Lian Q, Guan B, Liu QY, Meng M, Chen Y, Jin J, Li H, Liu X, Sun Z, Liu L, He QY, Zhang G
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Nobiletin Improves D-Galactose-Induced Aging Mice Skeletal Muscle Atrophy by Regulating Protein Homeostasis.
Wang HH, Zhang Y, Qu TQ, Sang XQ, Li YX, Ren FZ, Wen PC, Sun YN
Nutrients 2023 Apr 7;15(8)
Nutrients 2023 Apr 7;15(8)
Active ingredients screening and pharmacological mechanism research of curcumae rhizoma-sparganii rhizoma herb pair ameliorates liver fibrosis based on network pharmacology.
Hao M, Yao Z, Zhao M, Chen Z, Wang P, Sang X, Yang Q, Wang K, Han X, Cao G
Journal of ethnopharmacology 2023 Apr 6;305:116111
Journal of ethnopharmacology 2023 Apr 6;305:116111
Stearoyl-CoA Desaturases1 Accelerates Non-Small Cell Lung Cancer Metastasis by Promoting Aromatase Expression to Improve Estrogen Synthesis.
Chen J, Wang Y, Meng W, Zhao R, Lin W, Xiao H, Liao Y
International journal of molecular sciences 2023 Apr 6;24(7)
International journal of molecular sciences 2023 Apr 6;24(7)
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Zheng G, Su Y, Wei L, Yao Y, Wang Y, Luo X, Wang X, Ruan XZ, Li D, Chen Y
Cell death & disease 2023 Apr 6;14(4):249
Cell death & disease 2023 Apr 6;14(4):249
ANP32B promotes lung cancer progression by regulating VDAC1.
Li T, Wang N, Li S, Yan H, Gao S, Gao W, Xu R
Gene 2023 Apr 5;859:147200
Gene 2023 Apr 5;859:147200
TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition.
Song H, Xiao Q, Xu F, Wei Q, Wang F, Tan G
Chinese medical journal 2023 Apr 5;136(7):799-806
Chinese medical journal 2023 Apr 5;136(7):799-806
RUNX1 Upregulation Causes Mitochondrial Dysfunction via Regulating the PI3K-Akt Pathway in iPSC from Patients with Down Syndrome.
Liu Y, Zhang Y, Ren Z, Zeng F, Yan J
Molecules and cells 2023 Apr 30;46(4):219-230
Molecules and cells 2023 Apr 30;46(4):219-230
NMR-Based Metabolic Profiling of the Effects of α-Ketoglutarate Supplementation on Energy-Deficient C2C12 Myotubes.
Li Y, Zhang S, Huang C, Lin D
Molecules (Basel, Switzerland) 2023 Apr 30;28(9)
Molecules (Basel, Switzerland) 2023 Apr 30;28(9)
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling.
Xu X, Deng L, Tang Y, Li J, Zhong T, Hao X, Fan Y, Mu S
International journal of molecular sciences 2023 Apr 30;24(9)
International journal of molecular sciences 2023 Apr 30;24(9)
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Abdurahman A, Li Y, Jia SZ, Xu XW, Lin SJ, Ouyang P, Jun He Z, Zhang ZH, Liu Q, Xu Y, Song GL
Metallomics : integrated biometal science 2023 Apr 3;15(4)
Metallomics : integrated biometal science 2023 Apr 3;15(4)
Characterization of molecular subtypes based on chromatin regulators and identification of the role of NPAS2 in lung adenocarcinoma.
Huang Y, Xiao L, Daba MY, Xu D, Wang Y, Li L, Li Q, Liu B, Qin W, Zhang H, Yuan X
Clinical epigenetics 2023 Apr 29;15(1):72
Clinical epigenetics 2023 Apr 29;15(1):72
Pathophysiology of reinfection by exogenous HSV-1 is driven by heparanase dysfunction.
Suryawanshi RK, Patil CD, Agelidis A, Koganti R, Yadavalli T, Ames JM, Borase H, Shukla D
Science advances 2023 Apr 28;9(17):eadf3977
Science advances 2023 Apr 28;9(17):eadf3977
Investigation of the function of the novel tumor marker BEND5 in lung adenocarcinoma based on data mining and in vitro analysis.
Ma Y, Wu L
Journal of thoracic disease 2023 Apr 28;15(4):1749-1769
Journal of thoracic disease 2023 Apr 28;15(4):1749-1769
Establishment of a Rat Model of Liver Venous Deprivation: Simultaneous Portal and Hepatic Vein Ligation.
Zhang Y, He X, Ma P, Xiong L, Bai W, Zhang G, Xu Y, Song W, Yu K
Journal of clinical and translational hepatology 2023 Apr 28;11(2):393-404
Journal of clinical and translational hepatology 2023 Apr 28;11(2):393-404
RNF123 Mediates Ubiquitination and Degradation of SOCS1 To Regulate Type I Interferon Production during Duck Tembusu Virus Infection.
Huang S, Cui M, Huang J, Wu Z, Cheng A, Wang M, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Tian B, Sun D, Yin Z, Jing B, Jia R
Journal of virology 2023 Apr 27;97(4):e0009523
Journal of virology 2023 Apr 27;97(4):e0009523
Systemic Analyses of Cuproptosis-Related lncRNAs in Pancreatic Adenocarcinoma, with a Focus on the Molecular Mechanism of LINC00853.
Chen L, Zhang L, He H, Shao F, Gao Y, He J
International journal of molecular sciences 2023 Apr 27;24(9)
International journal of molecular sciences 2023 Apr 27;24(9)
RIPK1-Induced A1 Reactive Astrocytes in Brain in MPTP-Treated Murine Model of Parkinson's Disease.
Qiao C, Niu G, Zhao W, Quan W, Zhou Y, Zhang M, Li T, Zhou S, Huang W, Zhao L, Wu J, Cui C, Shen Y
Brain sciences 2023 Apr 27;13(5)
Brain sciences 2023 Apr 27;13(5)
Development and validation of novel prognostic models for zinc finger proteins-related genes in soft tissue sarcoma.
Li J, Zhou Q, Zhang C, Zhu H, Yao J, Zhang M
Aging 2023 Apr 26;15(8):3171-3190
Aging 2023 Apr 26;15(8):3171-3190
Isthmin-1 (Ism1) modulates renal branching morphogenesis and mesenchyme condensation during early kidney development.
Gao G, Li X, Jiang Z, Osorio L, Tang YL, Yu X, Jin G, Zhou Z
Nature communications 2023 Apr 25;14(1):2378
Nature communications 2023 Apr 25;14(1):2378
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Guo HH, Shen HR, Tang MZ, Sheng N, Ding X, Lin Y, Zhang JL, Jiang JD, Gao TL, Wang LL, Han YX
Journal of ethnopharmacology 2023 Apr 24;306:116158
Journal of ethnopharmacology 2023 Apr 24;306:116158
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Fu S, Song X, Tang X, Qian X, Du Z, Hu Y, Xu X, Zhang M
Journal of ethnopharmacology 2023 Apr 24;306:116050
Journal of ethnopharmacology 2023 Apr 24;306:116050
A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA.
Lu P, Yang J, Li M, Wen S, Zhang T, Yan C, Liu R, Xiao Y, Wang X, Jiang W
Genome biology 2023 Apr 24;24(1):92
Genome biology 2023 Apr 24;24(1):92
Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).
Duan Y, Yu J, Chen M, Lu Q, Ning F, Gan X, Liu H, Ye Y, Lu S, Lash GE
Journal of ovarian research 2023 Apr 22;16(1):81
Journal of ovarian research 2023 Apr 22;16(1):81
Human Embryonic Stem-Cell-Derived Exosomes Repress NLRP3 Inflammasome to Alleviate Pyroptosis in Nucleus Pulposus Cells by Transmitting miR-302c.
Yu Y, Li W, Xian T, Tu M, Wu H, Zhang J
International journal of molecular sciences 2023 Apr 21;24(8)
International journal of molecular sciences 2023 Apr 21;24(8)
Nuclear bodies protect phase separated proteins from degradation in stressed proteome.
Jung KH, Sun J, Hsiung CH, Lance Lian X, Liu Y, Zhang X
bioRxiv : the preprint server for biology 2023 Apr 21;
bioRxiv : the preprint server for biology 2023 Apr 21;
Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway.
Chen L, Huang J, Yao ZM, Sun XR, Tong XH, Hu M, Zhang Y, Dong SY
Molecules (Basel, Switzerland) 2023 Apr 20;28(8)
Molecules (Basel, Switzerland) 2023 Apr 20;28(8)
Ursolic Acid Alleviates Cancer Cachexia and Prevents Muscle Wasting via Activating SIRT1.
Tao W, Ouyang Z, Liao Z, Li L, Zhang Y, Gao J, Ma L, Yu S
Cancers 2023 Apr 20;15(8)
Cancers 2023 Apr 20;15(8)
Succinylation of CTBP1 mediated by KAT2A suppresses its inhibitory activity on the transcription of CDH1 to promote the progression of prostate cancer.
Zhou J, Yan X, Liu Y, Yang J
Biochemical and biophysical research communications 2023 Apr 2;650:9-16
Biochemical and biophysical research communications 2023 Apr 2;650:9-16
Pre-Protection and Mechanism of Crude Extracts from Dioscorea alata L. on H(2)O(2)-Induced IPEC-J2 Cells Oxidative Damage.
Yun Y, Shi H, Wang Y, Yang F, Zhang Y, Feng H, Chen J, Wang X
Animals : an open access journal from MDPI 2023 Apr 19;13(8)
Animals : an open access journal from MDPI 2023 Apr 19;13(8)
Antioxidant, Immunostimulatory, and Anticancer Properties of Hydrolyzed Wheat Bran Mediated through Macrophages Stimulation.
Tomé-Sánchez I, Martínez-Villaluenga C, Martín-Diana AB, Rico D, Jiménez-Pulido I, Frias J, Dia VP
International journal of molecular sciences 2023 Apr 18;24(8)
International journal of molecular sciences 2023 Apr 18;24(8)
Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2.
Zhang FL, Chen XW, Wang YF, Hu Z, Zhang WJ, Zhou BW, Ci PF, Liu KX
Journal of translational medicine 2023 Apr 18;21(1):264
Journal of translational medicine 2023 Apr 18;21(1):264
Genetic deletion of phosphodiesterase 4D in the liver improves kidney damage in high-fat fed mice: liver-kidney crosstalk.
Tao X, Chen C, Huang Z, Lei Y, Wang M, Wang S, Tian D
Cell death & disease 2023 Apr 18;14(4):273
Cell death & disease 2023 Apr 18;14(4):273
PIMT is a novel and potent suppressor of endothelial activation.
Zhang C, Guo ZF, Liu W, Kazama K, Hu L, Sun X, Wang L, Lee H, Lu L, Yang XF, Summer R, Sun J
eLife 2023 Apr 18;12
eLife 2023 Apr 18;12
STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy.
Wan W, Qian C, Wang Q, Li J, Zhang H, Wang L, Pu M, Huang Y, He Z, Zhou T, Shen HM, Liu W
The EMBO journal 2023 Apr 17;42(8):e112387
The EMBO journal 2023 Apr 17;42(8):e112387
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells.
Xie Y, Fan S, Ni D, Wan W, Xu P, Ding Y, Zhang R, Lu J, Zhang N, Zhang Y, Xiao W, Zhao K, Luo C
Bioorganic & medicinal chemistry 2023 Apr 15;84:117262
Bioorganic & medicinal chemistry 2023 Apr 15;84:117262
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Tang Y, Zhang J, Hu Z, Xu W, Xu P, Ma Y, Xing H, Niu Q
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
LDL Affects the Immunomodulatory Response of Endothelial Cells by Modulation of the Promyelocytic Leukemia Protein (PML) Expression via PKC.
Roos K, Berkholz J
International journal of molecular sciences 2023 Apr 15;24(8)
International journal of molecular sciences 2023 Apr 15;24(8)
Effects of ketamine-induced H3K9 hypoacetylation during pregnancy on cardiogenesis of mouse offspring.
Yu Y, Quan J, Zou M, Zhao W, Su Y, Xu Y
Birth defects research 2023 Apr 15;115(7):770-781
Birth defects research 2023 Apr 15;115(7):770-781
AKT Blocks SIK1-Mediated Repression of STAT3 to Promote Breast Tumorigenesis.
Sun Z, Jiang Q, Gao B, Zhang X, Bu L, Wang L, Lin Y, Xie W, Li J, Guo J
Cancer research 2023 Apr 14;83(8):1264-1279
Cancer research 2023 Apr 14;83(8):1264-1279
Protective Effects of Selenium Nanoparticles against Bisphenol A-Induced Toxicity in Porcine Intestinal Epithelial Cells.
Pan Z, Huang J, Hu T, Zhang Y, Zhang L, Zhang J, Cui D, Li L, Wang J, Wu Q
International journal of molecular sciences 2023 Apr 14;24(8)
International journal of molecular sciences 2023 Apr 14;24(8)
microRNA-660 Enhances Cisplatin Sensitivity via Decreasing SATB2 Expression in Lung Adenocarcinoma.
Wang Z, Zhou L, Chen B, Li X, Zou Q, Xu W, Fang L, Wu A, Li Z, Chen Y
Genes 2023 Apr 14;14(4)
Genes 2023 Apr 14;14(4)
Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation.
Xue S, Li Z, Ze X, Wu X, He C, Shuai W, Marlow M, Chen J, Scurr D, Zhu Z, Xu J, Xu S
Journal of medicinal chemistry 2023 Apr 13;66(7):5099-5117
Journal of medicinal chemistry 2023 Apr 13;66(7):5099-5117
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Ma Z, Liu Z, Li X, Zhang H, Han D, Xiong W, Zhou H, Yang X, Zeng Q, Ren H, Xu D
Biology 2023 Apr 11;12(4)
Biology 2023 Apr 11;12(4)
Salvianolic Acid B Reduces the Inflammation of Fat Grafts by Inhibiting the NF-Kb Signalling Pathway in Macrophages.
Sun JM, Ho CK, Gao Y, Chong CH, Liu YD, Liu YX, Zheng DN, Zhang YF, Yu L
Aesthetic surgery journal 2023 Apr 10;43(5):NP372-NP390
Aesthetic surgery journal 2023 Apr 10;43(5):NP372-NP390
The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter.
Li B, Chang X, Liang X, Liu T, Shen Y, Zhang Q, Yang X, Lyu Y, Liu L, Guo J, Wu M, Gao Y, Yan X, Wang T, Zhang W, Qiu Y, Zheng J
The Science of the total environment 2023 Apr 1;867:161416
The Science of the total environment 2023 Apr 1;867:161416
Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy.
Pu TT, Wu W, Liang PD, Du JC, Han SL, Deng XL, Du XJ
Journal of cardiovascular pharmacology 2023 Apr 1;81(4):259-269
Journal of cardiovascular pharmacology 2023 Apr 1;81(4):259-269
PM(2.5) induce myocardial injury in hyperlipidemic mice through ROS-pyroptosis signaling pathway.
Jia R, Wei M, Lei J, Meng X, Du R, Yang M, Lu X, Jiang Y, Cao R, Wang L, Song L
Ecotoxicology and environmental safety 2023 Apr 1;254:114699
Ecotoxicology and environmental safety 2023 Apr 1;254:114699
Prognostic marker C3AR1 is associated with ovarian cancer cell proliferation and immunosuppression in the tumor microenvironment.
Huang J, Zhou L, Deng K
Journal of ovarian research 2023 Apr 1;16(1):64
Journal of ovarian research 2023 Apr 1;16(1):64
Novel Experimental Mouse Model to Study Malaria-Associated Acute Kidney Injury.
Bensalel J, Roberts A, Hernandez K, Pina A, Prempeh W, Babalola BV, Cannata P, Lazaro A, Gallego-Delgado J
Pathogens (Basel, Switzerland) 2023 Apr 1;12(4)
Pathogens (Basel, Switzerland) 2023 Apr 1;12(4)
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
Liu LY, Qin TZ, Guo L, Rong-Rong H, Jing YT, Lai PP, Xue YZ, Ding GR
International journal of radiation biology 2022;98(8):1316-1329
International journal of radiation biology 2022;98(8):1316-1329
Altered mannose metabolism in chronic stress and depression is rapidly reversed by vitamin B12.
Franzka P, Turecki G, Cubillos S, Kentache T, Steiner J, Walter M, Hübner CA, Engmann O
Frontiers in nutrition 2022;9:981511
Frontiers in nutrition 2022;9:981511
Emodin from Aloe inhibits Swine acute diarrhea syndrome coronavirus in cell culture.
Zheng S, Wang X, Hu H, Xia Y, Diao X, Qiu W, Xue C, Cao Y, Xu Z
Frontiers in veterinary science 2022;9:978453
Frontiers in veterinary science 2022;9:978453
Ablation of cardiomyocyte-derived BDNF during development causes myocardial degeneration and heart failure in the adult mouse heart.
Li L, Guo H, Lai B, Liang C, Chen H, Chen Y, Guo W, Yuan Z, Huang R, Zeng Z, Liang L, Zhao H, Zheng X, Li Y, Pu Q, Qi X, Cai D
Frontiers in cardiovascular medicine 2022;9:967463
Frontiers in cardiovascular medicine 2022;9:967463
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Rui H, Zhao F, Yuhua L, Hong J
Frontiers in cardiovascular medicine 2022;9:951704
Frontiers in cardiovascular medicine 2022;9:951704
Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway.
Zheng X, Zhong T, Yu F, Duan J, Tang Y, Liu Y, Li M, Sun D, Yin D
Frontiers in cardiovascular medicine 2022;9:951463
Frontiers in cardiovascular medicine 2022;9:951463
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Liang Z, Miao Y, Teng X, Xiao L, Guo Q, Xue H, Tian D, Jin S, Wu Y
Frontiers in molecular biosciences 2022;9:947778
Frontiers in molecular biosciences 2022;9:947778
CircRNA-mediated regulation of brown adipose tissue adipogenesis.
Liu K, Liu X, Deng Y, Li Z, Tang A
Frontiers in nutrition 2022;9:926024
Frontiers in nutrition 2022;9:926024
Gypenosides ameliorate high-fat diet-induced non-alcoholic steatohepatitis via farnesoid X receptor activation.
Li H, Xi Y, Liu H, Xin X
Frontiers in nutrition 2022;9:914079
Frontiers in nutrition 2022;9:914079
Obesity by High-Fat Diet Increases Pain Sensitivity by Reprogramming Branched-Chain Amino Acid Catabolism in Dorsal Root Ganglia.
Lian N, Luo K, Xie H, Kang Y, Tang K, Lu P, Li T
Frontiers in nutrition 2022;9:902635
Frontiers in nutrition 2022;9:902635
Comparison of the Effects of Inorganic or Amino Acid-Chelated Zinc on Mouse Myoblast Growth in vitro and Growth Performance and Carcass Traits in Growing-Finishing Pigs.
Zhang L, Guo Q, Duan Y, Lin X, Ni H, Zhou C, Li F
Frontiers in nutrition 2022;9:857393
Frontiers in nutrition 2022;9:857393
Cardiac ISL1-Interacting Protein, a Cardioprotective Factor, Inhibits the Transition From Cardiac Hypertrophy to Heart Failure.
Yan Y, Long T, Su Q, Wang Y, Chen K, Yang T, Zhao G, Ma Q, Hu X, Liu C, Liao X, Min W, Li S, Zhang D, Yang Y, Pu WT, Dong Y, Wang DZ, Chen Y, Huang ZP
Frontiers in cardiovascular medicine 2022;9:857049
Frontiers in cardiovascular medicine 2022;9:857049
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Zou P, Zhang X, Zhang R, Chai X, Zhao Y, Li E, Zhang Q, Yan R, Yang J, Liao B
Frontiers in molecular biosciences 2022;9:853654
Frontiers in molecular biosciences 2022;9:853654
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
He X, Sun T, Zhang P, Xia Z, Gao C, Ren H, Ji D
Frontiers in medicine 2022;9:848938
Frontiers in medicine 2022;9:848938
Fructose Induces Insulin Resistance of Gestational Diabetes Mellitus in Mice via the NLRP3 Inflammasome Pathway.
Liu Y, Wei Y, Wu L, Lin X, Sun R, Chen H, Shen S, Deng G
Frontiers in nutrition 2022;9:839174
Frontiers in nutrition 2022;9:839174
Renal Denervation Attenuates Adverse Remodeling and Intramyocardial Inflammation in Acute Myocardial Infarction With Ischemia-Reperfusion Injury.
Wang K, Qi Y, Gu R, Dai Q, Shan A, Li Z, Gong C, Chang L, Hao H, Duan J, Xu J, Hu J, Mu D, Zhang N, Lu J, Wang L, Wu H, Li L, Kang L, Xu B
Frontiers in cardiovascular medicine 2022;9:832014
Frontiers in cardiovascular medicine 2022;9:832014
Antibiotic Therapy and Vaginal Microbiota Transplantation Reduce Endometriosis Disease Progression in Female Mice via NF-κB Signaling Pathway.
Lu F, Wei J, Zhong Y, Feng Y, Ma B, Xiong Y, Wei K, Tan B, Chen T
Frontiers in medicine 2022;9:831115
Frontiers in medicine 2022;9:831115
6-Shogaol Inhibits Oxidative Stress-Induced Rat Vascular Smooth Muscle Cell Apoptosis by Regulating OXR1-p53 Axis.
Liu J, Li B, Li W, Pan T, Diao Y, Wang F
Frontiers in molecular biosciences 2022;9:808162
Frontiers in molecular biosciences 2022;9:808162
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Song Q, Chen P, Wu SJ, Chen Y, Zhang Y
Frontiers in cardiovascular medicine 2022;9:746888
Frontiers in cardiovascular medicine 2022;9:746888
LncRNA FAM13A-AS1 Promotes Renal Carcinoma Tumorigenesis Through Sponging miR-141-3p to Upregulate NEK6 Expression.
Wang XJ, Li S, Fang J, Yan ZJ, Luo GC
Frontiers in molecular biosciences 2022;9:738711
Frontiers in molecular biosciences 2022;9:738711
Apigenin remodels the gut microbiota to ameliorate ulcerative colitis.
Fu R, Wang L, Meng Y, Xue W, Liang J, Peng Z, Meng J, Zhang M
Frontiers in nutrition 2022;9:1062961
Frontiers in nutrition 2022;9:1062961
Maternal nucleotide supplementation improves the intestinal morphology and immune function in lipopolysaccharide-challenged newborn piglets.
Li Q, Hung I, Bai K, Wang T
Frontiers in veterinary science 2022;9:1043842
Frontiers in veterinary science 2022;9:1043842
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Wang D, Yin L, Chen R, Tan W, Liang L, Xiang J, Zhang H, Zhou X, Deng H, Guo B, Wang Y
Frontiers in medicine 2022;9:1018298
Frontiers in medicine 2022;9:1018298
Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis.
Man W, Song X, Xiong Z, Gu J, Lin J, Gu X, Yu D, Li C, Jiang M, Zhang X, Yang Z, Cao Y, Zhang Y, Shu X, Wu D, Wang H, Ji G, Sun D
Frontiers in cardiovascular medicine 2022;9:1003282
Frontiers in cardiovascular medicine 2022;9:1003282
Experimental Periodontitis Deteriorates Cognitive Function and Impairs Insulin Signaling in a Streptozotocin-Induced Alzheimer's Disease Rat Model.
Duan L, Qian X, Wang Q, Huang L, Ge S
Journal of Alzheimer's disease : JAD 2022;88(1):57-74
Journal of Alzheimer's disease : JAD 2022;88(1):57-74
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
Zhang W, Zhang M, Wu Q, Shi J
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
Micro ribonucleic acid-448 regulates zinc finger e-box binding homeobox 1 to inhibit the growth of breast cancer cells and increase their sensitivity to chemotherapy.
Zhou Y, Sun L, Zhang Y, Chen K
Clinics (Sao Paulo, Brazil) 2022;77:100089
Clinics (Sao Paulo, Brazil) 2022;77:100089
MicroRNA-214-3p Ameliorates LPS-Induced Cardiomyocyte Injury by Inhibiting Cathepsin B.
Yan W, Feng Y, Lei Z, Kuang W, Long C
Folia biologica 2022;68(2):78-85
Folia biologica 2022;68(2):78-85
The involvement of hormone-sensitive lipase in all-trans retinoic acid induced cleft palate.
Zheng K, Ye QN
The International journal of developmental biology 2022;66(7-8-9):383-389
The International journal of developmental biology 2022;66(7-8-9):383-389
Effects of miR-211-3p/RHBDD1 axis on cell proliferation, cell cycle progression, and epithelial-mesenchymal transition in glioma.
Chen L, Wang X, Zhu Y, Liu F, Liu L, Jiang N
Folia neuropathologica 2022;60(2):195-209
Folia neuropathologica 2022;60(2):195-209
EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells.
Li Y, Feng J, Bian Y, Cheng W, Qiao C
Folia histochemica et cytobiologica 2022;60(1):31-43
Folia histochemica et cytobiologica 2022;60(1):31-43
Pterostilbene, a Resveratrol Derivative, Improves Ectopic Lipid Deposition in the Kidneys of Mice Induced by a High-Fat Diet.
Gu W, Yang L, Wang X, Geng J, Li X, Zheng K, Guan Y, Hou X, Wang C, Song G
Kidney & blood pressure research 2022;47(8):514-522
Kidney & blood pressure research 2022;47(8):514-522
MicroRNA-155-5p Targets NR3C2 to Promote Malignant Progression of Clear Cell Renal Cell Carcinoma.
Yan C, Wang P, Zhao C, Yin G, Meng X, Li L, Cai S, Meng B
Kidney & blood pressure research 2022;47(5):354-362
Kidney & blood pressure research 2022;47(5):354-362
Evacetrapib Elicits Antitumor Effects on Colorectal Cancer by Inhibiting the Wnt/β-Catenin Signaling Pathway and Activating the JNK Signaling Pathway.
Hu L, Dong H, He L, Shi M, Xiang N, Su Y, Wang C, Tian Y, Hu Y, Wang H, Liu H, Wen C, Yang X
Biological & pharmaceutical bulletin 2022;45(9):1238-1245
Biological & pharmaceutical bulletin 2022;45(9):1238-1245
Hyperthermia inhibits growth of nasopharyngeal carcinoma through degradation of c-Myc.
Li X, Duan S, Zheng Y, Yang Y, Wang L, Li X, Zhang Q, Thorne RF, Li W, Yang D
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):358-371
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):358-371
Tanshinone IIA ameliorates myocardial ischemia/reperfusion injury in rats by regulation of NLRP3 inflammasome activation and Th17 cells differentiation.
Li D, Yang Z, Gao S, Zhang H, Fan G
Acta cirurgica brasileira 2022;37(7):e370701
Acta cirurgica brasileira 2022;37(7):e370701
MiR-96-5p induced NDRG1 deficiency promotes prostate cancer migration and invasion through regulating the NF-κB signaling pathway.
Lian Z, Chang T, Ma S, Li J, Zhang H, Wang X, Liu R
Cancer biomarkers : section A of Disease markers 2022;35(1):83-98
Cancer biomarkers : section A of Disease markers 2022;35(1):83-98
Gallbladder Cancer Cell-Derived Exosome-Mediated Transfer of Leptin Promotes Cell Invasion and Migration by Modulating STAT3-Mediated M2 Macrophage Polarization.
Zhao S, Liu Y, He L, Li Y, Lin K, Kang Q, Liu L, Zou H
Analytical cellular pathology (Amsterdam) 2022;2022:9994906
Analytical cellular pathology (Amsterdam) 2022;2022:9994906
Irisin Ameliorates Intervertebral Disc Degeneration by Activating LATS/YAP/CTGF Signaling.
Chen T, Lin Y, Wu Z, Shi H, Hu W, Li S, Que Y, Qiu J, Li P, Qiu X, Liang T, Wang X, Gao B, Zhou H, Deng Z, Chen Y, Zhu Y, Peng Y, Liang A, Gao W, Huang D
Oxidative medicine and cellular longevity 2022;2022:9684062
Oxidative medicine and cellular longevity 2022;2022:9684062
The DeltaN p63 Promotes EMT and Metastasis in Bladder Cancer by the PTEN/AKT Signalling Pathway.
Tian YH, He YF, Tan JS, Jiang Y, Xu Q, Cheng HL
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9566055
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9566055
Transcriptional Patterns of Lower-Grade Glioma Patients with Distinct Ferroptosis Levels, Immunotherapy Response, and Temozolomide Sensitivity.
Tu Z, Li J, Long X, Wu L, Zhu X, Huang K
Oxidative medicine and cellular longevity 2022;2022:9408886
Oxidative medicine and cellular longevity 2022;2022:9408886
Downregulation of S100A9 Reverses Cisplatin-Resistance and Inhibits Proliferation and Migration in Hypopharyngeal Carcinoma.
Zeng S, Tan G, Wang T, Wang X, Zhou Z, Xiao J, Li T, Zhang G, Li W
Journal of oncology 2022;2022:9341731
Journal of oncology 2022;2022:9341731
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress.
Qiu Y, Li C, Zhang B
BioMed research international 2022;2022:9329151
BioMed research international 2022;2022:9329151
Effect and Mechanism of lncRNA CERS6-AS1 on the Biological Behavior of Prostate Cancer Cell.
Huang F, Zhou LQ
Applied bionics and biomechanics 2022;2022:9292538
Applied bionics and biomechanics 2022;2022:9292538
Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis.
He J, Wan C, Li X, Zhang Z, Yang Y, Wang H, Qi Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9122315
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9122315
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
Zhang X, Sun M, Jiao Y, Lin B, Yang Q
Oxidative medicine and cellular longevity 2022;2022:9029544
Oxidative medicine and cellular longevity 2022;2022:9029544
FKN/NR Signaling Pathway Regulates Hippocampal Inflammatory Responses: the Survival of Hippocampal Neurons in Diabetic Rats with Chronic Unpredictable Mild Stress.
Liu Z, Zhao H, Liu J, Han Y, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8980627
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8980627
circ-Katnal1 Enhances Inflammatory Pyroptosis in Sepsis-Induced Liver Injury through the miR-31-5p/GSDMD Axis.
Kang K, Li N, Gao Y, Wang C, Chen P, Meng X, Yang W, Zhao M, Yu K
Mediators of inflammation 2022;2022:8950130
Mediators of inflammation 2022;2022:8950130
The E3 Ubiquitin Ligase TRIM11 Facilitates Gastric Cancer Progression by Activating the Wnt/β-Catenin Pathway via Destabilizing Axin1 Protein.
Zhou L, Wang H, Zhong M, Fang Z, Le Y, Nie F, Zhou J, Xiong J, Xiang X, Fang Z
Journal of oncology 2022;2022:8264059
Journal of oncology 2022;2022:8264059
Long Intergenic Noncoding RNA 00641 Promotes Growth and Invasion of Colorectal Cancer through Regulating miR-450b-5p/GOLPH3 Axis.
Hong Z, Pan J, Chen M, Deng X, Chen Z, Wang C, Qiu C
Journal of oncology 2022;2022:8259135
Journal of oncology 2022;2022:8259135
In Vitro Immunomodulatory Effects of Inonotus obliquus Extracts on Resting M0 Macrophages and LPS-Induced M1 Macrophages.
Shen D, Feng Y, Zhang X, Liu J, Gong L, Liao H, Li R
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8251344
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8251344
Hypoxia Acclimation Protects against Heart Failure Postacute Myocardial Infarction via Fundc1-Mediated Mitophagy.
Li Q, Liu Y, Huang Q, Yi X, Qin F, Zhong Z, Lin L, Yang H, Gong G, Wu W
Oxidative medicine and cellular longevity 2022;2022:8192552
Oxidative medicine and cellular longevity 2022;2022:8192552
Apigenin Induced Apoptosis by Downregulating Sulfiredoxin Expression in Cutaneous Squamous Cell Carcinoma.
Wang W, Liu X, Zhang Z, Yin M, Chen X, Zhao S, Wu L
Oxidative medicine and cellular longevity 2022;2022:8172866
Oxidative medicine and cellular longevity 2022;2022:8172866
Effect of Lycium barbarum Polysaccharide on Decreasing Serum Amyloid A3 Expression through Inhibiting NF-κB Activation in a Mouse Model of Diabetic Nephropathy.
Wan F, Ma F, Wu J, Qiao X, Chen M, Li W, Ma L
Analytical cellular pathology (Amsterdam) 2022;2022:7847135
Analytical cellular pathology (Amsterdam) 2022;2022:7847135
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
Gong H, Gao M, Lin Y, Liu J, Hu Z, Liu J
Oxidative medicine and cellular longevity 2022;2022:7843863
Oxidative medicine and cellular longevity 2022;2022:7843863
UHRF1 Induces Metastasis in Thyroid Cancer.
Kuang BH, Lin GH, Liu Q, Wang BC
Journal of oncology 2022;2022:7716427
Journal of oncology 2022;2022:7716427
Protective Effects of Herba Houttuyniae Aqueous Extract against OVA-Induced Airway Hyperresponsiveness and Inflammation in Asthmatic Mice.
Yang Y, Lai Q, Wang C, Zhou G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7609785
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7609785
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
Gao Y, Feng L, Zhang L, Geng J, Zhang E
Disease markers 2022;2022:7527996
Disease markers 2022;2022:7527996
YTHDC1 Promotes Stemness Maintenance and Malignant Progression in Head and Neck Squamous Cell Carcinoma.
Weng J, Fan H, Liu H, Tang S, Zheng Y
Stem cells international 2022;2022:7494354
Stem cells international 2022;2022:7494354
Fucoxanthin Attenuates Oxidative Damage by Activating the Sirt1/Nrf2/HO-1 Signaling Pathway to Protect the Kidney from Ischemia-Reperfusion Injury.
Mao H, Wang L, Xiong Y, Jiang G, Liu X
Oxidative medicine and cellular longevity 2022;2022:7444430
Oxidative medicine and cellular longevity 2022;2022:7444430
Exploring the Potential Mechanism of Qi-Shen-Di-Huang Drug Formulary for Myasthenia Gravis (MG) based on UHPLC-QE-MS Network Pharmacology and Molecular Docking Techniques.
Zhang Y, Chang T, Lu Q, Cui Y, Zhang D, Wang B, Xu P, Lu J, Ma J, Lv Z, Wang J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7416448
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7416448
Inhibition of Angiogenesis by MiR-524-5p through Suppression of AKT and ERK Activation by Targeting CXCR7 in Colon Cancer Cells.
Li X, Li Z, Li C, Fang Y, Zhang G, Yan Y, Zhao X, Song X, Zhang Z
Journal of oncology 2022;2022:7224840
Journal of oncology 2022;2022:7224840
Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21.
Huang R, Zou C, Zhang C, Wang X, Zou X, Xiang Z, Wang Z, Gui B, Lin T, Hu H
Oxidative medicine and cellular longevity 2022;2022:7142314
Oxidative medicine and cellular longevity 2022;2022:7142314
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Wu W, Gou H, Xiang B, Geng R, Dong J, Yang X, Chen D, Dai R, Chen L, Liu J
Journal of oncology 2022;2022:7099589
Journal of oncology 2022;2022:7099589
MicroRNA-323a-3p Negatively Regulates NEK6 in Colon Adenocarcinoma Cells.
Hong Z, Chen Z, Pan J, Shi Z, Wang C, Qiu C
Journal of oncology 2022;2022:7007718
Journal of oncology 2022;2022:7007718
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Wen Y, Li Y, Yang B, Guo X, Lin L, Liang J, Zhang K, Li X, Jiang Z, Wang Y, Li Y, Wu X, Fan X, Li F, Yuan W
Disease markers 2022;2022:6993994
Disease markers 2022;2022:6993994
Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo.
Li Y, Shi D, Zhang H, Yao X, Ren K
Analytical cellular pathology (Amsterdam) 2022;2022:6984200
Analytical cellular pathology (Amsterdam) 2022;2022:6984200
Role of GLI1 in Hypoxia-Driven Endometrial Stromal Cell Migration and Invasion in Endometriosis.
Wang L, Liang J, Bi S, Li Y, Zhang W, Xiwen W, Liu Y, Liu H
Computational and mathematical methods in medicine 2022;2022:6890790
Computational and mathematical methods in medicine 2022;2022:6890790
Effects of Sodium Chlorophyllin Copper on APO-1 Expression in Bone Marrow Mesenchymal Stem Cells of Rats with Aplastic Anaemia.
Jin X, Dai G, Xuan L, Zhang M, Jiang H, Sui Y
Journal of immunology research 2022;2022:6792866
Journal of immunology research 2022;2022:6792866
Comprehensive Pan-Cancer Analysis of IRAK Family Genes Identifies IRAK1 as a Novel Oncogene in Low-Grade Glioma.
Li J, Sun Y, Ma Y, Zhao X, Sun X, Wang Y, Zhang X
Journal of oncology 2022;2022:6497241
Journal of oncology 2022;2022:6497241
Glaucocalyxin B Attenuates Ovarian Cancer Cell Growth and Cisplatin Resistance In Vitro via Activating Oxidative Stress.
Zhang T, Xu C, Zheng P, Zhang X, Qiu C, Wu F, Chen J, Xiao Z, Zhu J, Zhang J, Zou P, Ni D
Oxidative medicine and cellular longevity 2022;2022:6324292
Oxidative medicine and cellular longevity 2022;2022:6324292
Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain.
Xi P, Mao R, Wu S, Liu L, Cai C, Lu L, Zhang C, Li Y
Mediators of inflammation 2022;2022:6010952
Mediators of inflammation 2022;2022:6010952
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Zhang B, Wan S, Liu H, Qiu Q, Chen H, Chen Z, Wang L, Liu X
Oxidative medicine and cellular longevity 2022;2022:5992436
Oxidative medicine and cellular longevity 2022;2022:5992436
Metformin Exhibits an Attractive Antineoplastic Effect on Human Endometrial Cancer by Regulating the Hippo Signaling Pathway.
Wang M, Zhang Q, Li Y, Jin L, Fang Z
Journal of oncology 2022;2022:5824617
Journal of oncology 2022;2022:5824617
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Shi H, Yan Y, Yang H, Pu P, Tang H
BioMed research international 2022;2022:5623555
BioMed research international 2022;2022:5623555
miR-212 Promotes Cardiomyocyte Hypertrophy through Regulating Transcription Factor 7 Like 2.
Yuan J, Yuan G
Mediators of inflammation 2022;2022:5187218
Mediators of inflammation 2022;2022:5187218
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
Long Noncoding RNA Hotair Promotes the Progression and Immune Escape in Laryngeal Squamous Cell Carcinoma through MicroRNA-30a/GRP78/PD-L1 Axis.
Yuan X, Shen Q, Ma W
Journal of immunology research 2022;2022:5141426
Journal of immunology research 2022;2022:5141426
Network Pharmacology and Experimental Validation to Reveal Effects and Mechanisms of Icariin Combined with Nobiletin against Chronic Obstructive Pulmonary Diseases.
Lu R, Xu K, Qin Y, Shao X, Yan M, Liao Y, Wang B, Zhao J, Li J, Tian Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4838650
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4838650
MiRNA-196-5p Promotes Proliferation and Migration in Cholangiocarcinoma via HAND1/Wnt/β-Catenin Signaling Pathway.
Liu C, Li Y, Zhang L, Zhang P, Yu N, Liu X, Lu H, Du H, Hou S
Journal of oncology 2022;2022:4599676
Journal of oncology 2022;2022:4599676
Wound Healing Effects of Dracontomelon dao on Bacterial Infection Wounds in Rats and Its Potential Mechanisms under Simulated Space Environment.
Wen J, Xu Z, Ma X, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4593201
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4593201
Ferroptosis-Specific Inhibitor Ferrostatin-1 Relieves H(2)O(2)-Induced Redox Imbalance in Primary Cardiomyocytes through the Nrf2/ARE Pathway.
Sun C, Peng F, Li J, Cui X, Qiao X, Zhu W
Disease markers 2022;2022:4539932
Disease markers 2022;2022:4539932
ZNF165 Is Involved in the Regulation of Immune Microenvironment and Promoting the Proliferation and Migration of Hepatocellular Carcinoma by AhR/CYP1A1.
Liu P, Zhou Y, Dong X, Zheng B, Liang B, Liang R, Liu Z, Li L, Gong P
Journal of immunology research 2022;2022:4446805
Journal of immunology research 2022;2022:4446805
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
Tang Y, Huo X, Liu J, Tang Y, Zhang M, Xie W, Zheng Z, He J, Lian J
Cardiovascular therapeutics 2022;2022:4382999
Cardiovascular therapeutics 2022;2022:4382999
Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m(6)A Modification of MAT2A Pre-mRNA by METTL16.
Chen PB, Shi GX, Liu T, Li B, Jiang SD, Zheng XF, Jiang LS
Oxidative medicine and cellular longevity 2022;2022:4036274
Oxidative medicine and cellular longevity 2022;2022:4036274
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Peng Y, Liao B, Zhou Y, Zeng W, Zeng ZY
Cardiology research and practice 2022;2022:3972829
Cardiology research and practice 2022;2022:3972829
Ferritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2'-Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester.
Guan D, Zhou W, Wei H, Wang T, Zheng K, Yang C, Feng R, Xu R, Fu Y, Li C, Li Y, Li C
Oxidative medicine and cellular longevity 2022;2022:3920664
Oxidative medicine and cellular longevity 2022;2022:3920664
Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway.
Niu S, Jing M, Wen J, Wei S, Li H, Li X, Ma X, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3498310
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3498310
The Oral Tumor Cell Exosome miR-10b Stimulates Cell Invasion and Relocation via AKT Signaling.
Li X, Yang T, Shu C
Contrast media & molecular imaging 2022;2022:3188992
Contrast media & molecular imaging 2022;2022:3188992
CPE Regulates Proliferation and Apoptosis of Primary Myocardial Cells Mediated by Ischemia and Hypoxia Injury.
Li J, Dong Z, Pan Y, Wang L, Zhao W, Jian Zhang
Journal of healthcare engineering 2022;2022:3155171
Journal of healthcare engineering 2022;2022:3155171
Effects of Vitexin, a Natural Flavonoid Glycoside, on the Proliferation, Invasion, and Apoptosis of Human U251 Glioblastoma Cells.
Huang J, Zhou Y, Zhong X, Su F, Xu L
Oxidative medicine and cellular longevity 2022;2022:3129155
Oxidative medicine and cellular longevity 2022;2022:3129155
Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke.
Sun E, Zhang J, Deng Y, Wang J, Wu Q, Chen W, Ma X, Chen S, Xiang X, Chen Y, Wu T, Yang Y, Chen B
Oxidative medicine and cellular longevity 2022;2022:3119649
Oxidative medicine and cellular longevity 2022;2022:3119649
Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/eNOS Pathway.
Wang S, Tan J, Chen L, Wang J
Journal of oncology 2022;2022:2956888
Journal of oncology 2022;2022:2956888
Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.
Li B, Lu ZY, Jiang SD, Jiang LS, Zheng XF
Oxidative medicine and cellular longevity 2022;2022:2912276
Oxidative medicine and cellular longevity 2022;2022:2912276
Intermittent Hypoxia Inhibits Hepatic CYP1a2 Expression and Delays Aminophylline Metabolism.
Zhang XB, Chen XY, Chiu KY, He XZ, Wang JM, Zeng HQ, Zeng Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2782702
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2782702
Analysis of Therapeutic Targets of A Novel Peptide Athycaltide-1 in the Treatment of Isoproterenol-Induced Pathological Myocardial Hypertrophy.
Zheng X, Su F, Kang Z, Li J, Zhang C, Zhang Y, Hao L
Cardiovascular therapeutics 2022;2022:2715084
Cardiovascular therapeutics 2022;2022:2715084
Resveratrol Alleviates Skeletal Muscle Insulin Resistance by Downregulating Long Noncoding RNA.
Liu Z, Zhang Z, Song G, Wang X, Xing H, Wang C
International journal of endocrinology 2022;2022:2539519
International journal of endocrinology 2022;2022:2539519
Ketone Body β-Hydroxybutyrate Prevents Myocardial Oxidative Stress in Septic Cardiomyopathy.
Ji L, He Q, Liu Y, Deng Y, Xie M, Luo K, Cai X, Zuo Y, Wu W, Li Q, Zhou R, Li T
Oxidative medicine and cellular longevity 2022;2022:2513837
Oxidative medicine and cellular longevity 2022;2022:2513837
Hydroxytyrosol Ameliorates Intervertebral Disc Degeneration and Neuropathic Pain by Reducing Oxidative Stress and Inflammation.
Yu H, Zhang Z, Wei F, Hou G, You Y, Wang X, Cao S, Yang X, Liu W, Zhang S, Hu F, Zhang X
Oxidative medicine and cellular longevity 2022;2022:2240894
Oxidative medicine and cellular longevity 2022;2022:2240894
Mitochondria-Targeted Antioxidant Mitoquinone Maintains Mitochondrial Homeostasis through the Sirt3-Dependent Pathway to Mitigate Oxidative Damage Caused by Renal Ischemia/Reperfusion.
Mao H, Zhang Y, Xiong Y, Zhu Z, Wang L, Liu X
Oxidative medicine and cellular longevity 2022;2022:2213503
Oxidative medicine and cellular longevity 2022;2022:2213503
Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway.
Li S, Shi Y, Zhang S, Li H, Ye Z, Kong J, Hong W, Tu Y, Ren J, Meftah Z, Xie C, Wang X, Zhang X
Oxidative medicine and cellular longevity 2022;2022:2188145
Oxidative medicine and cellular longevity 2022;2022:2188145
Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway.
Yang Y, He B, Zhang X, Yang R, Xia X, Chen L, Li R, Shen Z, Chen P
Oxidative medicine and cellular longevity 2022;2022:2152746
Oxidative medicine and cellular longevity 2022;2022:2152746
Identification of FABP7 as a Potential Biomarker for Predicting Prognosis and Antiangiogenic Drug Efficacy of Glioma.
Hou L, Zhou H, Wang Y, Liu J, Zhang D, Li Y, Xue X
Disease markers 2022;2022:2091791
Disease markers 2022;2022:2091791
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Li C, Zhu L, Dai Y, Zhang Z, Huang L, Wang TJ, Fu P, Li Y, Wang J, Jiang C
Oxidative medicine and cellular longevity 2022;2022:1599747
Oxidative medicine and cellular longevity 2022;2022:1599747
Tanshinone IIA Accomplished Protection against Radiation-Induced Cardiomyocyte Injury by Regulating the p38/p53 Pathway.
Wang G, Ma L, Wang B, Gao F, Li J, Cai H, Wang J, Zhang T, Guo H, Xie P, Li Y
Mediators of inflammation 2022;2022:1478181
Mediators of inflammation 2022;2022:1478181
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Mao Y, Du J, Chen X, Al Mamun A, Cao L, Yang Y, Mubwandarikwa J, Zaeem M, Zhang W, Chen Y, Dai Y, Xiao J, Ye K
Oxidative medicine and cellular longevity 2022;2022:1337630
Oxidative medicine and cellular longevity 2022;2022:1337630
GNAI2 Is a Risk Factor for Gastric Cancer: Study of Tumor Microenvironment (TME) and Establishment of Immune Risk Score (IRS).
Yu H, Liu S, Wu Z, Gao F
Oxidative medicine and cellular longevity 2022;2022:1254367
Oxidative medicine and cellular longevity 2022;2022:1254367
New inhibitors of cathepsin V impair tumor cell proliferation and elastin degradation and increase immune cell cytotoxicity.
Mitrović A, Senjor E, Jukić M, Bolčina L, Prunk M, Proj M, Nanut MP, Gobec S, Kos J
Computational and structural biotechnology journal 2022;20:4667-4687
Computational and structural biotechnology journal 2022;20:4667-4687
FBXO17 Inhibits the Wnt/β-Catenin Pathway and Proliferation of Ishikawa Cells.
Zheng ZM, Wang YY, Chen M, Yang HL, Lai ZZ, Li MQ, Shao J
International journal of medical sciences 2022;19(9):1430-1441
International journal of medical sciences 2022;19(9):1430-1441
Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.
Wang Y, Wang H, Zhuo Y, Hu Y, Li X, Xu Y, Sun B, Liu M, Zou L, Liu L, Luo L, Zhao C, Li P, Zhou Q
International journal of biological sciences 2022;18(9):3676-3696
International journal of biological sciences 2022;18(9):3676-3696
Yap is essential for uterine decidualization through Rrm2/GSH/ROS pathway in response to Bmp2.
Yu HF, Yang ZQ, Xu MY, Huang JC, Yue ZP, Guo B
International journal of biological sciences 2022;18(6):2261-2276
International journal of biological sciences 2022;18(6):2261-2276
TET1s deficiency exacerbates oscillatory shear flow-induced atherosclerosis.
Qu K, Wang C, Huang L, Qin X, Zhang K, Zhong Y, Ma Q, Yan W, Li T, Peng Q, Wang Y, Gregersen H, Tang C, Qiu J, Wang G
International journal of biological sciences 2022;18(5):2163-2180
International journal of biological sciences 2022;18(5):2163-2180
4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis.
Zhang P, Wang Y, Yang W, Yin Y, Li C, Ma X, Shi L, Li R, Tao K
International journal of biological sciences 2022;18(16):6189-6209
International journal of biological sciences 2022;18(16):6189-6209
GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway.
Zhang J, Wang H, Wu J, Yuan C, Chen S, Liu S, Huo M, Zhang C, He Y
International journal of biological sciences 2022;18(16):6068-6083
International journal of biological sciences 2022;18(16):6068-6083
Anp32e promotes renal interstitial fibrosis by upregulating the expression of fibrosis-related proteins.
Wei J, Shan Y, Xiao Z, Wen L, Tao Y, Fang X, Luo H, Tang C, Li Y
International journal of biological sciences 2022;18(15):5897-5912
International journal of biological sciences 2022;18(15):5897-5912
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Li B, Chen J, Wu Y, Luo H, Ke Y
International journal of biological sciences 2022;18(13):5123-5135
International journal of biological sciences 2022;18(13):5123-5135
DNA Polymerase Gamma Recovers Mitochondrial Function and Inhibits Vascular Calcification by Interacted with p53.
Wang P, Wu B, You S, Lu S, Xiong S, Zou Y, Jia P, Guo X, Zhang Y, Cao L, Sun Y, Zhang N
International journal of biological sciences 2022;18(1):409-425
International journal of biological sciences 2022;18(1):409-425
Rab31 promotes the invasion and metastasis of cervical cancer cells by inhibiting MAPK6 degradation.
Huang Y, Liu R, Han X, Hou X, Tian Y, Zhang W
International journal of biological sciences 2022;18(1):112-123
International journal of biological sciences 2022;18(1):112-123
Vocal changes in a zebra finch model of Parkinson's disease characterized by alpha-synuclein overexpression in the song-dedicated anterior forebrain pathway.
Medina CA, Vargas E, Munger SJ, Miller JE
PloS one 2022;17(5):e0265604
PloS one 2022;17(5):e0265604
Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus.
Wen C, Yu Y, Gao C, Qi X, Cardona CJ, Xing Z
PloS one 2022;17(4):e0257408
PloS one 2022;17(4):e0257408
Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress.
Preninka AI, Kuriya K, Yazawa K, Yoshii M, Yanase Y, Jockers R, Dam J, Hosoi T, Ozawa K
PloS one 2022;17(12):e0278965
PloS one 2022;17(12):e0278965
GPC2 deficiency inhibits cell growth and metastasis in colon adenocarcinoma.
Lin L, He Y, Ni Z, Zhang M, Liu J, Mao Q, Huang B, Lin J
Open medicine (Warsaw, Poland) 2022;17(1):304-316
Open medicine (Warsaw, Poland) 2022;17(1):304-316
Dezocine inhibits cell proliferation, migration, and invasion by targeting CRABP2 in ovarian cancer.
Zhang C, Pan R, Ma S, Xu S, Wang B
Open medicine (Warsaw, Poland) 2022;17(1):2052-2061
Open medicine (Warsaw, Poland) 2022;17(1):2052-2061
β2-Adrenergic receptor expression in subchondral bone of patients with varus knee osteoarthritis.
Yang X, Liang X, Guo H, Ma L, Jian L, Zhao X, Wang J, Yang L, Meng Z, Jin Q
Open medicine (Warsaw, Poland) 2022;17(1):1031-1044
Open medicine (Warsaw, Poland) 2022;17(1):1031-1044
Superparamagnetic Iron Oxide Nanoparticles Protect Human Gingival Fibroblasts from Porphyromonas gingivalis Invasion and Inflammatory Stimulation.
Chen Y, Zhang Q, Qin X, Li J, Zhao Y, Xia Y
International journal of nanomedicine 2022;17:45-60
International journal of nanomedicine 2022;17:45-60
Exosome Derived from Mesenchymal Stem Cells Alleviates Pathological Scars by Inhibiting the Proliferation, Migration and Protein Expression of Fibroblasts via Delivering miR-138-5p to Target SIRT1.
Zhao W, Zhang R, Zang C, Zhang L, Zhao R, Li Q, Yang Z, Feng Z, Zhang W, Cui R
International journal of nanomedicine 2022;17:4023-4038
International journal of nanomedicine 2022;17:4023-4038
N-Methyl D-aspartate receptor subtype 2B/Ca(2+)/calmodulin-dependent protein kinase II signaling in the lateral habenula regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia.
Zhuang ZF, Wu HY, Song YY, Li L, Cui X, Yang J, Xu XQ, Cui WQ
Frontiers in cellular neuroscience 2022;16:981190
Frontiers in cellular neuroscience 2022;16:981190
Microglial infiltration mediates cognitive dysfunction in rat models of hypothalamic obesity via a hypothalamic-hippocampal circuit involving the lateral hypothalamic area.
Song C, Wei W, Wang T, Zhou M, Li Y, Xiao B, Huang D, Gu J, Shi L, Peng J, Jin D
Frontiers in cellular neuroscience 2022;16:971100
Frontiers in cellular neuroscience 2022;16:971100
Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death.
Yang Y, Chen X, Tian K, Tian C, Chen L, Mi W, Li Q, Qiu J, Lin Y, Zha D
Frontiers in cellular neuroscience 2022;16:783346
Frontiers in cellular neuroscience 2022;16:783346
Endothelin-1, over-expressed in SOD1(G93A) mice, aggravates injury of NSC34-hSOD1G93A cells through complicated molecular mechanism revealed by quantitative proteomics analysis.
Zhang Y, Chen L, Li Z, Li D, Wu Y, Guo Y
Frontiers in cellular neuroscience 2022;16:1069617
Frontiers in cellular neuroscience 2022;16:1069617
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
Yang X, Xu Y, Gao W, Wang L, Zhao X, Liu G, Fan K, Liu S, Hao H, Qu S, Dong R, Ma X, Ma J
Frontiers in neuroscience 2022;16:1036872
Frontiers in neuroscience 2022;16:1036872
Receptor-Interacting Protein Kinase 3 Inhibition Relieves Mechanical Allodynia and Suppresses NLRP3 Inflammasome and NF-κB in a Rat Model of Spinal Cord Injury.
Xue S, Cao ZX, Wang JN, Zhao QX, Han J, Yang WJ, Sun T
Frontiers in molecular neuroscience 2022;15:861312
Frontiers in molecular neuroscience 2022;15:861312
Adipose Dysfunction in Adulthood Insulin Resistance of Low-Birth Weight Mice: A Proteomics Study.
Wang J, Yang L, Yang L, Zhou F, Zhao H, Liu J, Ma H, Song G
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:849-862
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:849-862
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
Yang QQ, Li HN, Xia YT, Tian X, Feng F, Yang J, Xu YL, Guo J, Li XQ, Wang JY, Zeng XY
Frontiers in molecular neuroscience 2022;15:820664
Frontiers in molecular neuroscience 2022;15:820664
Beclin1 Deficiency Suppresses Epileptic Seizures.
Yang M, Lin P, Jing W, Guo H, Chen H, Chen Y, Guo Y, Gu Y, He M, Wu J, Jiang X, Zou Z, Xu X, Chen C, Xiao F, Wang X, Tian X
Frontiers in molecular neuroscience 2022;15:807671
Frontiers in molecular neuroscience 2022;15:807671
TNF-α and IL-1β Promote Renal Podocyte Injury in T2DM Rats by Decreasing Glomerular VEGF/eNOS Expression Levels and Altering Hemodynamic Parameters.
Wang J, Feng Y, Zhang Y, Liu J, Gong L, Zhang X, Liao H
Journal of inflammation research 2022;15:6657-6673
Journal of inflammation research 2022;15:6657-6673
Sodium Tanshinone IIA Sulfonate Inhibits Vascular Endothelial Cell Pyroptosis via the AMPK Signaling Pathway in Atherosclerosis.
Zhu J, Chen H, Guo J, Zha C, Lu D
Journal of inflammation research 2022;15:6293-6306
Journal of inflammation research 2022;15:6293-6306
C-X-C-Chemokine-Receptor-Type-4 Inhibitor AMD3100 Attenuates Pulmonary Inflammation and Fibrosis in Silicotic Mice.
Sun Q, Tao X, Li B, Cao H, Chen H, Zou Y, Tao H, Mu M, Wang W, Xu K
Journal of inflammation research 2022;15:5827-5843
Journal of inflammation research 2022;15:5827-5843
Genome Wide Differential Expression Profiles in Nevus Sebaceous Uncovered Low Expression of CDKN2AIP and Construction of a ceRNA Network.
Yang X, Qiao R, Ni N, Zhang Q, Zhang K, Shao X, Cheng W, Sun J, Jiang Y
Clinical, cosmetic and investigational dermatology 2022;15:519-533
Clinical, cosmetic and investigational dermatology 2022;15:519-533
Palmitate Induces Mitochondrial Energy Metabolism Disorder and Cellular Damage via the PPAR Signaling Pathway in Diabetic Cardiomyopathy.
Zhang X, Mao M, Zuo Z
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:2287-2299
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:2287-2299
Endothelial Microparticles Derived from Primary Pulmonary Microvascular Endothelial Cells Mediate Lung Inflammation in Chronic Obstructive Pulmonary Disease by Transferring microRNA-126.
Ma Y, He X, Liu X, Long Y, Chen Y
Journal of inflammation research 2022;15:1399-1411
Journal of inflammation research 2022;15:1399-1411
Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma.
Qian Y, Li Y, Chen K, Liu N, Hong X, Wu D, Xu Z, Zhou L, Xu L, Jia R, Ge YZ
Journal of inflammation research 2022;15:1099-1116
Journal of inflammation research 2022;15:1099-1116
Decitabine improves MMS-induced retinal photoreceptor cell damage by targeting DNMT3A and DNMT3B.
Ji Y, Zhao M, Qiao X, Peng GH
Frontiers in molecular neuroscience 2022;15:1057365
Frontiers in molecular neuroscience 2022;15:1057365
Pirfenidone Attenuates Renal Tubulointerstitial Fibrosis through Inhibiting miR-21.
Bi L, Huang Y, Li J, Yang X, Hou G, Zhai P, Zhang Q, Alhaji AA, Yang Y, Liu B
Nephron 2022;146(1):110-120
Nephron 2022;146(1):110-120
A novel ferroptosis-related gene signature to predict overall survival in patients with osteosarcoma.
Li J, Wu F, Xiao X, Su L, Guo X, Yao J, Zhu H
American journal of translational research 2022;14(9):6082-6094
American journal of translational research 2022;14(9):6082-6094
Probiotic Saccharomyces boulardii attenuates cardiopulmonary bypass-induced acute lung injury by inhibiting ferroptosis.
Li J, Gao PF, Xu YX, Gu H, Wang QX
American journal of translational research 2022;14(7):5003-5013
American journal of translational research 2022;14(7):5003-5013
Over-expression of miR-193a-3p regulates the apoptosis of colorectal cancer cells by targeting PAK3.
Ma T, Li H, Yang W, Liu Q, Yan H
American journal of translational research 2022;14(2):1361-1375
American journal of translational research 2022;14(2):1361-1375
Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.
Zhang FK, Ni QZ, Wang K, Cao HJ, Guan DX, Zhang EB, Ma N, Wang YK, Zheng QW, Xu S, Zhu B, Chen TW, Xia J, Qiu XS, Ding XF, Jiang H, Qiu L, Wang X, Chen W, Cheng SQ, Xie D, Li JJ
Cellular and molecular gastroenterology and hepatology 2022;14(1):101-127
Cellular and molecular gastroenterology and hepatology 2022;14(1):101-127
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Huang X, Yao Y, Hou X, Wei L, Rao Y, Su Y, Zheng G, Ruan XZ, Li D, Chen Y
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
KLF16 Downregulates the Expression of Tumor Suppressor Gene TGFBR3 to Promote Bladder Cancer Proliferation and Migration.
Chen X, Wang P, Ou T, Li J
Cancer management and research 2022;14:465-477
Cancer management and research 2022;14:465-477
METTL3 Facilitates Tumor Progression by COL12A1/MAPK Signaling Pathway in Esophageal Squamous Cell Carcinoma.
Li J, Li Z, Xu Y, Huang C, Shan B
Journal of Cancer 2022;13(6):1972-1984
Journal of Cancer 2022;13(6):1972-1984
Promoter Methylation-Mediated NPTX2 Silencing Promotes Tumor Growth in Human Prostate Cancer.
Su Y, Huang Q, Lu L, Qu H, Wang D, Qiu J, Li W, Lin M, Liu H, Wang Z, Yang X
Journal of Cancer 2022;13(2):706-714
Journal of Cancer 2022;13(2):706-714
Dietary choline, via gut microbe- generated trimethylamine-N- oxide, aggravates chronic kidney disease-induced cardiac dysfunction by inhibiting hypoxia-induced factor 1α.
Xie F, Zhen X, Liu Z, Chen X, Liu Z, Zhou M, Zhou Z, Hu Z, Zhu F, Huang Q, Zhang L, Nie J
Frontiers in physiology 2022;13:996166
Frontiers in physiology 2022;13:996166
Exploratory study of sea buckthorn enhancing QiangGuYin efficacy by inhibiting CKIP-1 and Notum activating the Wnt/β-catenin signaling pathway and analysis of active ingredients by molecular docking.
Yuan YF, Wang S, Zhou H, Tang BB, Liu Y, Huang H, He CJ, Chen TP, Fang MH, Liang BC, Mao YD, Qie FQ, Liu K, Shi XL
Frontiers in pharmacology 2022;13:994995
Frontiers in pharmacology 2022;13:994995
Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway.
Wang C, Mei X, Wu Y, Yang Y, Zeng Z
Frontiers in pharmacology 2022;13:994625
Frontiers in pharmacology 2022;13:994625
Deciphering the active constituents of Dabushen decoction of ameliorating osteoarthritis via PPARγ preservation by targeting DNMT1.
Qiu L, Zhang M, Li C, Hou Y, Liu H, Lin J, Yao J, Duan DZ, Zhang YX, Li M, Li YL, Wang P, Li JT, Jin XJ, Liu YQ
Frontiers in pharmacology 2022;13:993498
Frontiers in pharmacology 2022;13:993498
Exploring the pharmacological mechanisms of icaritin against nasopharyngeal carcinoma via network pharmacology and experimental validation.
Liu M, Hu T, Gou W, Chang H, Li Y, Li Y, Zuo D, Hou W, Jiao S
Frontiers in pharmacology 2022;13:993022
Frontiers in pharmacology 2022;13:993022
Signature construction and molecular subtype identification based on cuproptosis-related genes to predict the prognosis and immune activity of patients with hepatocellular carcinoma.
Peng X, Zhu J, Liu S, Luo C, Wu X, Liu Z, Li Y, Yuan R
Frontiers in immunology 2022;13:990790
Frontiers in immunology 2022;13:990790
Indentification of novel MSTO1 compound heterozygous mutations in a Chinese family with recessive cerebellar atrophy and ataxia.
Chen J, Xiao J, Chen G, Xu Q, Wu X, Tian L, Huang Z, Xin C, Zhao Y, Guo Z, Zou Y, Wu Q
Frontiers in neurology 2022;13:988519
Frontiers in neurology 2022;13:988519
Comprehensive analysis for cellular senescence-related immunogenic characteristics and immunotherapy prediction of acute myeloid leukemia.
Mao Y, Xu J, Xu X, Qiu J, Hu Z, Jiang F, Zhou G
Frontiers in pharmacology 2022;13:987398
Frontiers in pharmacology 2022;13:987398
DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress.
Zhang H, Wang L, Yang Y, Cai C, Wang X, Deng L, He B, Zhou W, Cui Y
Frontiers in pharmacology 2022;13:987293
Frontiers in pharmacology 2022;13:987293
Acacetin protects against depression-associated dry eye disease by regulating ubiquitination of NLRP3 through gp78 signal.
Xie M, Wang H, Peng J, Qing D, Zhang X, Guo D, Meng P, Luo Z, Wang X, Peng Q
Frontiers in pharmacology 2022;13:984475
Frontiers in pharmacology 2022;13:984475
Identification of prognostic gene expression signatures based on the tumor microenvironment characterization of gastric cancer.
Sang Q, Dai W, Yu J, Chen Y, Fan Z, Liu J, Li F, Li J, Wu X, Hou J, Yu B, Feng H, Zhu ZG, Su L, Li YY, Liu B
Frontiers in immunology 2022;13:983632
Frontiers in immunology 2022;13:983632
Macrophage malfunction in Triptolide-induced indirect hepatotoxicity.
Qin T, Hasnat M, Zhou Y, Yuan Z, Zhang W
Frontiers in pharmacology 2022;13:981996
Frontiers in pharmacology 2022;13:981996
Combinatorial suicide gene strategies for the safety of cell therapies.
Falcon C, Smith L, Al-Obaidi M, Abu Zaanona M, Purvis K, Minagawa K, Athar M, Salzman D, Bhatia R, Goldman F, Di Stasi A
Frontiers in immunology 2022;13:975233
Frontiers in immunology 2022;13:975233
LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2.
Zhang C, Kang T, Wang X, Wang J, Liu L, Zhang J, Liu X, Li R, Wang J, Zhang J
Frontiers in pharmacology 2022;13:968223
Frontiers in pharmacology 2022;13:968223
Screening and identification of tissue-infiltrating immune cells and genes for patients with emphysema phenotype of COPD.
Wang D, Chen B, Bai S, Zhao L
Frontiers in immunology 2022;13:967357
Frontiers in immunology 2022;13:967357
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
Luo Q, Ling Y, Li Y, Qu X, Shi Q, Zheng S, Li Y, Huang Y, Zhou X
Frontiers in pharmacology 2022;13:964829
Frontiers in pharmacology 2022;13:964829
Integrating network pharmacology and experimental validation to clarify the anti-hyperuricemia mechanism of cortex phellodendri in mice.
Xu L, Cheng J, Lu J, Lin G, Yu Q, Li Y, Chen J, Xie J, Su Z, Zhou Q
Frontiers in pharmacology 2022;13:964593
Frontiers in pharmacology 2022;13:964593
Shenkang injection improves chronic kidney disease by inhibiting multiple renin-angiotensin system genes by blocking the Wnt/β-catenin signalling pathway.
Wang YN, Liu HJ, Ren LL, Suo P, Zou L, Zhang YM, Yu XY, Zhao YY
Frontiers in pharmacology 2022;13:964370
Frontiers in pharmacology 2022;13:964370
Identification of nine signature proteins involved in periodontitis by integrated analysis of TMT proteomics and transcriptomics.
Liu W, Qiu W, Huang Z, Zhang K, Wu K, Deng K, Chen Y, Guo R, Wu B, Chen T, Fang F
Frontiers in immunology 2022;13:963123
Frontiers in immunology 2022;13:963123
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis.
Li F, Wang Y, Tian J, Zhou Z, Yin W, Qin X, Wang H, Zeng T, Li A, Jiang J
Frontiers in pharmacology 2022;13:962770
Frontiers in pharmacology 2022;13:962770
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Hexavalent Chromium Exposure Induces Intestinal Barrier Damage via Activation of the NF-κB Signaling Pathway and NLRP3 Inflammasome in Ducks.
Xing C, Yang F, Lin Y, Shan J, Yi X, Ali F, Zhu Y, Wang C, Zhang C, Zhuang Y, Cao H, Hu G
Frontiers in immunology 2022;13:952639
Frontiers in immunology 2022;13:952639
Aging-related features predict prognosis and immunotherapy efficacy in hepatocellular carcinoma.
Hong T, Su W, Pan Y, Tian C, Lei G
Frontiers in immunology 2022;13:951459
Frontiers in immunology 2022;13:951459
Autoinducer-2 promotes Pseudomonas aeruginosa PAO1 acute lung infection via the IL-17A pathway.
Li H, Li X, Ai Q, Tan L
Frontiers in microbiology 2022;13:948646
Frontiers in microbiology 2022;13:948646
Class IIa histone deacetylase inhibition ameliorates acute kidney injury by suppressing renal tubular cell apoptosis and enhancing autophagy and proliferation.
Li J, Yu C, Shen F, Cui B, Liu N, Zhuang S
Frontiers in pharmacology 2022;13:946192
Frontiers in pharmacology 2022;13:946192
Pharmacological suppression of Nedd4-2 rescues the reduction of Kv11.1 channels in pathological cardiac hypertrophy.
Zhang H, Fu T, Sun J, Zou S, Qiu S, Zhang J, Su S, Shi C, Li DP, Xu Y
Frontiers in pharmacology 2022;13:942769
Frontiers in pharmacology 2022;13:942769
Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects.
Liu Z, Tu M, Shi J, Zhou H, Meng G, Gu J, Wang Y
Frontiers in pharmacology 2022;13:939317
Frontiers in pharmacology 2022;13:939317
Involvement of integrin αvβ3 in thyroid hormone-induced dendritogenesis.
Ariyani W, Miyazaki W, Amano I, Koibuchi N
Frontiers in endocrinology 2022;13:938596
Frontiers in endocrinology 2022;13:938596
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Shao Y, Sun L, Yang G, Wang W, Liu X, Du T, Chen F, Jing X, Cui X
Frontiers in pharmacology 2022;13:937502
Frontiers in pharmacology 2022;13:937502
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Li B, Wang HY, Huang JH, Xu WF, Feng XJ, Xiong ZP, Dong YJ, Li LZ, He X, Wu HS, Zhang K, Su J, Yu QX, Jiang NH, Lv GY, Chen SH
Frontiers in pharmacology 2022;13:935714
Frontiers in pharmacology 2022;13:935714
High Expression of ATP6V1C2 Predicts Unfavorable Overall Survival in Patients With Colon Adenocarcinoma.
Li G, Huang J, Chen S, He Y, Wang Z, Peng J
Frontiers in genetics 2022;13:930876
Frontiers in genetics 2022;13:930876
Salusin-β, a TOR2A gene product, promotes proliferation, migration, fibrosis, and calcification of smooth muscle cells and accelerates the imbalance of vasomotor function and vascular remodeling in monocrotaline-induced pulmonary hypertensive rats.
Wang X, Chen A, Hu R, Zhang F, Liang S, Bao C, Liu X, Tang H, Han Y
Frontiers in pharmacology 2022;13:928834
Frontiers in pharmacology 2022;13:928834
GSK3β-dependent lysosome biogenesis: An effective pathway to mitigate renal fibrosis with LM49.
Ren J, Wei H, Sun J, Feng X, Zhang Y, Yuan H, Miao J, Qi X, Qiao Y, Xiao B, Li Q
Frontiers in pharmacology 2022;13:925489
Frontiers in pharmacology 2022;13:925489
Jian-Pi-Yi-Shen Formula Improves Adenine-Induced Chronic Kidney Disease via Regulating Tryptophan Metabolism and Aryl Hydrocarbon Receptor Signaling.
Liu X, Deng R, Chen Y, Huang S, Lu J, Zheng L, Xiong G, Li S
Frontiers in pharmacology 2022;13:922707
Frontiers in pharmacology 2022;13:922707
Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation.
Xia B, Li Q, Wu J, Yuan X, Wang F, Lu X, Huang C, Zheng K, Yang R, Yin L, Liu K, You Q
Frontiers in pharmacology 2022;13:922484
Frontiers in pharmacology 2022;13:922484
Dao-Chi Powder Ameliorates Pancreatitis-Induced Intestinal and Cardiac Injuries via Regulating the Nrf2-HO-1-HMGB1 Signaling Pathway in Rats.
Yao J, Miao Y, Zhang Y, Zhu L, Chen H, Wu X, Yang Y, Dai X, Hu Q, Wan M, Tang W
Frontiers in pharmacology 2022;13:922130
Frontiers in pharmacology 2022;13:922130
Clostridium butyricum Protects Against Pancreatic and Intestinal Injury After Severe Acute Pancreatitis via Downregulation of MMP9.
Yan Q, Jia L, Wen B, Wu Y, Zeng Y, Wang Q
Frontiers in pharmacology 2022;13:919010
Frontiers in pharmacology 2022;13:919010
Persistent Activation of Autophagy After Cisplatin Nephrotoxicity Promotes Renal Fibrosis and Chronic Kidney Disease.
Fu Y, Xiang Y, Wu W, Cai J, Tang C, Dong Z
Frontiers in pharmacology 2022;13:918732
Frontiers in pharmacology 2022;13:918732
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Wang X, Yan K, Fu M, Liang S, Zhao H, Fu C, Yang L, Song Z, Sun D, Wan C
Frontiers in microbiology 2022;13:900919
Frontiers in microbiology 2022;13:900919
Establishment and Phenotypic Analysis of the Novel Gaucher Disease Mouse Model With the Partially Humanized Gba1 Gene and F213I Mutation.
Guo JN, Guan M, Jiang N, Li N, Li YJ, Zhang J, Ma D
Frontiers in genetics 2022;13:892457
Frontiers in genetics 2022;13:892457
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Li MT, Liu LL, Zhou Q, Huang LX, Shi YX, Hou JB, Lu HT, Yu B, Chen W, Guo ZY
Frontiers in pharmacology 2022;13:891788
Frontiers in pharmacology 2022;13:891788
Dihydroarteannuin Ameliorates Collagen-Induced Arthritis Via Inhibiting B Cell Activation by Activating the FcγRIIb/Lyn/SHP-1 Pathway.
Hu C, Wu D, Yu J, Xu J, Liu L, Zhang M, Jiao W, Chen G
Frontiers in pharmacology 2022;13:883835
Frontiers in pharmacology 2022;13:883835
C/EBPα Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus.
Qu H, Zong Q, Wang H, Wu S, Cai D, Bao W
Frontiers in immunology 2022;13:881289
Frontiers in immunology 2022;13:881289
NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen Species.
Harijith A, Basa P, Ha A, Thomas J, Jafri A, Fu P, MacFarlane PM, Raffay TM, Natarajan V, Sudhadevi T
Frontiers in pharmacology 2022;13:880878
Frontiers in pharmacology 2022;13:880878
Theabrownin and Poria cocos Polysaccharide Improve Lipid Metabolism via Modulation of Bile Acid and Fatty Acid Metabolism.
Wang J, Zheng D, Huang F, Zhao A, Kuang J, Ren Z, Chen T, Lei J, Lin J, Wang X, Jia W, Xie G, Zheng X
Frontiers in pharmacology 2022;13:875549
Frontiers in pharmacology 2022;13:875549
Emodin Ameliorates Acute Pancreatitis-Associated Lung Injury Through Inhibiting the Alveolar Macrophages Pyroptosis.
Wu X, Yao J, Hu Q, Kang H, Miao Y, Zhu L, Li C, Zhao X, Li J, Wan M, Tang W
Frontiers in pharmacology 2022;13:873053
Frontiers in pharmacology 2022;13:873053
Long-Acting β(2) Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis.
Xu R, Feng S, Ao Z, Chen Y, Su C, Feng X, Fu Q, Yang X
Frontiers in pharmacology 2022;13:865715
Frontiers in pharmacology 2022;13:865715
MiR-103a-3p Promotes Zika Virus Replication by Targeting OTU Deubiquitinase 4 to Activate p38 Mitogen-Activated Protein Kinase Signaling Pathway.
Ye H, Kang L, Yan X, Li S, Huang Y, Mu R, Duan X, Chen L
Frontiers in microbiology 2022;13:862580
Frontiers in microbiology 2022;13:862580
RGMa Participates in the Blood-Brain Barrier Dysfunction Through BMP/BMPR/YAP Signaling in Multiple Sclerosis.
Zhang L, Tang S, Ma Y, Liu J, Monnier P, Li H, Zhang R, Yu G, Zhang M, Li Y, Feng J, Qin X
Frontiers in immunology 2022;13:861486
Frontiers in immunology 2022;13:861486
Comprehensive Analysis of circRNAs, miRNAs, and mRNAs Expression Profiles and ceRNA Networks in Decidua of Unexplained Recurrent Spontaneous Abortion.
Liu X, Wu J, Nie H, Zhu X, Song G, Han L, Qin W
Frontiers in genetics 2022;13:858641
Frontiers in genetics 2022;13:858641
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Luo S, Li Y, Li S, Jiang R, Deng F, Liu G, Zhang J
Frontiers in physiology 2022;13:856427
Frontiers in physiology 2022;13:856427
Prognostic Biomarker KIF18A and Its Correlations With Immune Infiltrates and Mitosis in Glioma.
Tao BY, Liu YY, Liu HY, Zhang ZH, Guan YQ, Wang H, Shi Y, Zhang J
Frontiers in genetics 2022;13:852049
Frontiers in genetics 2022;13:852049
Identification of Polysaccharides From Dipsacus asperoides and Their Effects on Osteoblast Proliferation and Differentiation in a High-Glucose Environment.
Xu D, Liu J, Zheng W, Gao Q, Gao Y, Leng X
Frontiers in pharmacology 2022;13:851956
Frontiers in pharmacology 2022;13:851956
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Shi B, Xu FF, Xiang CP, Li CY, Fan P, Wang H
Frontiers in pharmacology 2022;13:851401
Frontiers in pharmacology 2022;13:851401
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
Sun J, Pan Y, Li X, Wang L, Liu M, Tu P, Wu C, Xiao J, Han Q, Da W, Ma Y, Guo Y
Frontiers in endocrinology 2022;13:849544
Frontiers in endocrinology 2022;13:849544
The Role of P4HA1 in Multiple Cancer Types and its Potential as a Target in Renal Cell Carcinoma.
Li Y, Ge YZ, Qian Y, Chen K, Zhao F, Qin Z, Zhou L, Xu L, Xu Z, Dou Q, Jia R
Frontiers in genetics 2022;13:848456
Frontiers in genetics 2022;13:848456
Dendrobium Nobile Lindl. Alkaloid Suppresses NLRP3-Mediated Pyroptosis to Alleviate LPS-Induced Neurotoxicity.
Li DD, Fan HX, Yang R, Li YY, Zhang F, Shi JS
Frontiers in pharmacology 2022;13:846541
Frontiers in pharmacology 2022;13:846541
Pan-cancer analysis of ASB3 and the potential clinical implications for immune microenvironment of glioblastoma multiforme.
Mu L, Han Z, Yu S, Wang A, Chen D, Kong S, Gu Y, Xu L, Liu A, Sun R, Long Y
Frontiers in immunology 2022;13:842524
Frontiers in immunology 2022;13:842524
Vitamin D Deficiency Impacts Exposure and Response of Pravastatin in Male Rats by Altering Hepatic OATPs.
Peng J, Yang G, Huang Z
Frontiers in pharmacology 2022;13:841954
Frontiers in pharmacology 2022;13:841954
SHP2 Inhibitors Show Anti-Myeloma Activity and Synergize With Bortezomib in the Treatment of Multiple Myeloma.
Zhou P, Xiao M, Li W, Sun X, Bai Y, Meng F, Zhu Z, Yuan W, Sun K
Frontiers in pharmacology 2022;13:841308
Frontiers in pharmacology 2022;13:841308
Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.
Guo H, Liu R, He J, Yao W, Zheng W
Frontiers in physiology 2022;13:841149
Frontiers in physiology 2022;13:841149
Cyclophosphamide Induces the Ferroptosis of Tumor Cells Through Heme Oxygenase-1.
Shi H, Hou B, Li H, Zhou H, Du B
Frontiers in pharmacology 2022;13:839464
Frontiers in pharmacology 2022;13:839464
Protein Disulfide-Isomerase A3 Is a Robust Prognostic Biomarker for Cancers and Predicts the Immunotherapy Response Effectively.
Tu Z, Ouyang Q, Long X, Wu L, Li J, Zhu X, Huang K
Frontiers in immunology 2022;13:837512
Frontiers in immunology 2022;13:837512
Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4.
Miyauchi Y, Kimura A, Sawai M, Fujimoto K, Hirota Y, Tanaka Y, Takechi S, Mackenzie PI, Ishii Y
Frontiers in pharmacology 2022;13:832931
Frontiers in pharmacology 2022;13:832931
Acute Administration of Metformin Protects Against Neuronal Apoptosis Induced by Cerebral Ischemia-Reperfusion Injury via Regulation of the AMPK/CREB/BDNF Pathway.
Liu K, Li L, Liu Z, Li G, Wu Y, Jiang X, Wang M, Chang Y, Jiang T, Luo J, Zhu J, Li H, Wang Y
Frontiers in pharmacology 2022;13:832611
Frontiers in pharmacology 2022;13:832611
The Role of the Negative Regulation of Microglia-Mediated Neuroinflammation in Improving Emotional Behavior After Epileptic Seizures.
Wu Q, Wang H, Liu X, Zhao Y, Zhang J
Frontiers in neurology 2022;13:823908
Frontiers in neurology 2022;13:823908
Cochlear Marginal Cell Pyroptosis Is Induced by Cisplatin via NLRP3 Inflammasome Activation.
Yu W, Zong S, Zhou P, Wei J, Wang E, Ming R, Xiao H
Frontiers in immunology 2022;13:823439
Frontiers in immunology 2022;13:823439
Baohuoside I Inhibits Tumor Angiogenesis in Multiple Myeloma via the Peroxisome Proliferator-Activated Receptor γ/Vascular Endothelial Growth Factor Signaling Pathway.
Chen Y, Zhang L, Zang X, Shen X, Li J, Chen L
Frontiers in pharmacology 2022;13:822082
Frontiers in pharmacology 2022;13:822082
Tanreqing Injection Attenuates Macrophage Activation and the Inflammatory Response via the lncRNA-SNHG1/HMGB1 Axis in Lipopolysaccharide-Induced Acute Lung Injury.
Hu C, Li J, Tan Y, Liu Y, Bai C, Gao J, Zhao S, Yao M, Lu X, Qiu L, Xing L
Frontiers in immunology 2022;13:820718
Frontiers in immunology 2022;13:820718
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Yuan Y, Hu Q, Liu L, Xie F, Yang L, Li Y, Zhang C, Chen H, Tang J, Shen X
Frontiers in pharmacology 2022;13:817596
Frontiers in pharmacology 2022;13:817596
Role of Suprabasin in the Dedifferentiation of Follicular Epithelial Cell-Derived Thyroid Cancer and Identification of Related Immune Markers.
Tan H, Wang L, Liu Z
Frontiers in genetics 2022;13:810681
Frontiers in genetics 2022;13:810681
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps.
Dong C, Chen Z, Zhu L, Bsoul N, Wu H, Jiang J, Chen X, Lai Y, Yu G, Gu Y, Guo X, Gao W
Frontiers in pharmacology 2022;13:809034
Frontiers in pharmacology 2022;13:809034
Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopausal Mice.
Chen Y, Zhang L, Li Z, Wu Z, Lin X, Li N, Shen R, Wei G, Yu N, Gong F, Rui G, Xu R, Ji G
Frontiers in pharmacology 2022;13:803880
Frontiers in pharmacology 2022;13:803880
Pan-Cancer Analysis Reveals a Distinct Neutrophil Extracellular Trap-Associated Regulatory Pattern.
Shen XT, Xie SZ, Xu J, Yang LY, Qin LX
Frontiers in immunology 2022;13:798022
Frontiers in immunology 2022;13:798022
Atractylenolide III Attenuates Angiogenesis in Gastric Precancerous Lesions Through the Downregulation of Delta-Like Ligand 4.
Gao Y, Wang J, Zhao M, Xia T, Liu Q, Chen N, Liao W, Zeng Z, You F, Zeng J
Frontiers in pharmacology 2022;13:797805
Frontiers in pharmacology 2022;13:797805
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Deng Y, Li H, Song Y, Cen J, Zhang Y, Sui Y, Cui D, Li TC, Xu Y, Wang CC, Chung PWJ, Tang T
Frontiers in endocrinology 2022;13:781149
Frontiers in endocrinology 2022;13:781149
Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway.
Peng L, Chen Y, Li Y, Feng P, Zheng Y, Dong Y, Yang Y, Wang R, Li A, Yan J, Shang F, Tang P, Chen D, Gao Y, Huang W
Frontiers in pharmacology 2022;13:767705
Frontiers in pharmacology 2022;13:767705
NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.
Chen J, Ge J, Zhang W, Xie X, Zhong X, Tang S
Frontiers in genetics 2022;13:764957
Frontiers in genetics 2022;13:764957
Natural product manoalide promotes EGFR-TKI sensitivity of lung cancer cells by KRAS-ERK pathway and mitochondrial Ca(2+) overload-induced ferroptosis.
Ni Y, Liu J, Zeng L, Yang Y, Liu L, Yao M, Chai L, Zhang L, Li Y, Zhang L, Li W
Frontiers in pharmacology 2022;13:1109822
Frontiers in pharmacology 2022;13:1109822
Desmosterol: A natural product derived from macroalgae modulates inflammatory response and oxidative stress pathways in intestinal epithelial cells.
Qu H, Zong Q, Hu P, Li Z, Wang H, Wu S, Liu HY, Bao W, Cai D
Frontiers in immunology 2022;13:1101643
Frontiers in immunology 2022;13:1101643
Exploration and validation of a combined immune and metabolism gene signature for prognosis prediction of colorectal cancer.
Xiao Y, Zhang G, Wang L, Liang M
Frontiers in endocrinology 2022;13:1069528
Frontiers in endocrinology 2022;13:1069528
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells.
Qu N, Qu J, Huang N, Zhang K, Ye T, Shi J, Chen B, Kan C, Zhang J, Han F, Hou N, Sun X, Pan R
Frontiers in pharmacology 2022;13:1056687
Frontiers in pharmacology 2022;13:1056687
Calcitriol-enhanced autophagy in gingival epithelium attenuates periodontal inflammation in rats with type 2 diabetes mellitus.
Wang Y, Huang M, Xu W, Li F, Ma C, Tang X
Frontiers in endocrinology 2022;13:1051374
Frontiers in endocrinology 2022;13:1051374
ADAR1 promotes systemic sclerosis via modulating classic macrophage activation.
Sun C, Cai D, Chen SY
Frontiers in immunology 2022;13:1051254
Frontiers in immunology 2022;13:1051254
MLN2238 exerts its anti-tumor effects via regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma.
Xu H, Xu G, Xu Q, Xu C, Zhou X, Bai Y, Yin L, Ding Y, Wang W
Frontiers in pharmacology 2022;13:1040847
Frontiers in pharmacology 2022;13:1040847
Berberine prevents lethal EV71 neurological infection in newborn mice.
Cui G, Wang H, Yang C, Zhou X, Wang J, Wang T, Ma T
Frontiers in pharmacology 2022;13:1027566
Frontiers in pharmacology 2022;13:1027566
Ginsenoside Rg1 interferes with the progression of diabetic osteoporosis by promoting type H angiogenesis modulating vasculogenic and osteogenic coupling.
Chen W, Jin X, Wang T, Bai R, Shi J, Jiang Y, Tan S, Wu R, Zeng S, Zheng H, Jia H, Li S
Frontiers in pharmacology 2022;13:1010937
Frontiers in pharmacology 2022;13:1010937
Effects of scoparone on non-alcoholic fatty liver disease revealed by RNA sequencing.
Huang X, Gao Y, Cao H, Li J, Mo S, Li T, Wu J, Guo K, Wei R, Zhang K
Frontiers in endocrinology 2022;13:1004284
Frontiers in endocrinology 2022;13:1004284
Characterization and subcellular localization of Alongshan virus proteins.
Zhao Y, Wu P, Liu L, Ma B, Pan M, Huang Y, Du N, Yu H, Sui L, Wang ZD, Hou Z, Liu Q
Frontiers in microbiology 2022;13:1000322
Frontiers in microbiology 2022;13:1000322
Fibroblast activation protein α activatable theranostic pro-photosensitizer for accurate tumor imaging and highly-specific photodynamic therapy.
Luo Y, Zeng Z, Shan T, Xu X, Chen J, He Y, Zhang T, Huang Z, Chai G, Huang Y, Zhao Y, Zhao C
Theranostics 2022;12(8):3610-3627
Theranostics 2022;12(8):3610-3627
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
Yang S, Zhang Y, Guo C, Liu R, Elkharti M, Ge Z, Liu Q, Liu S, Sun MZ
American journal of cancer research 2022;12(6):2492-2525
American journal of cancer research 2022;12(6):2492-2525
A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway.
Huang PY, Shih IA, Liao YC, You HL, Lee MJ
American journal of cancer research 2022;12(2):873-892
American journal of cancer research 2022;12(2):873-892
RNA N(6) -methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer.
Tan B, Zhou K, Liu W, Prince E, Qing Y, Li Y, Han L, Qin X, Su R, Pokharel SP, Yang L, Zhao Z, Shen C, Li W, Chen Z, Zhang Z, Deng X, Small A, Wang K, Leung K, Chen CW, Shen B, Chen J
Theranostics 2022;12(13):5727-5743
Theranostics 2022;12(13):5727-5743
CPSF1 positively regulates NSDHL by alternative polyadenylation and promotes gastric cancer progression.
Kang W, Yang Y, Chen C, Yu C
American journal of cancer research 2022;12(10):4566-4583
American journal of cancer research 2022;12(10):4566-4583
WWOX-rs13338697 genotype predicts therapeutic efficacy of ADI-PEG 20 for patients with advanced hepatocellular carcinoma.
Chu YD, Liu HF, Chen YC, Chou CH, Yeh CT
Frontiers in oncology 2022;12:996820
Frontiers in oncology 2022;12:996820
Combined treatment of marizomib and cisplatin modulates cervical cancer growth and invasion and enhances antitumor potential in vitro and in vivo.
Zhang Z, Zhang S, Lin B, Wang Q, Nie X, Shi Y
Frontiers in oncology 2022;12:974573
Frontiers in oncology 2022;12:974573
PKIB involved in the metastasis and survival of osteosarcoma.
Wan R, Yang G, Liu Q, Fu X, Liu Z, Miao H, Liu H, Huang W
Frontiers in oncology 2022;12:965838
Frontiers in oncology 2022;12:965838
A comprehensive role evaluation and mechanism exploration of POGLUT2 in pan-cancer.
Xu X, Xie G, Xie M, Liu Q
Frontiers in oncology 2022;12:962540
Frontiers in oncology 2022;12:962540
Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11.
Gao H, He Z, Gao C, Liu N, Zhang Z, Niu W, Niu J, Peng C
Frontiers in oncology 2022;12:936507
Frontiers in oncology 2022;12:936507
The Novel LncRNA WASH5P Inhibits Colorectal Cancer Carcinogenesis via Targeting AKT Signaling Pathway.
Wei H, Mao T, Zhang Q, Ren K, Qi X, Zhang Y, Cao B, Jin Y, Tian Z, Ren L
Frontiers in oncology 2022;12:923425
Frontiers in oncology 2022;12:923425
FOSL1 promotes tumor growth and invasion in ameloblastoma.
Xiong G, Ouyang S, Xie N, Xie J, Wang W, Yi C, Zhang M, Xu X, Chen D, Wang C
Frontiers in oncology 2022;12:900108
Frontiers in oncology 2022;12:900108
Cold Atmospheric Plasma Conveys Selectivity Against Hepatocellular Carcinoma Cells via Triggering EGFR(Tyr1068)-Mediated Autophagy.
Wang D, Zhang J, Cai L, Dai X
Frontiers in oncology 2022;12:895106
Frontiers in oncology 2022;12:895106
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
Wen X, Chen S, Chen X, Qiu H, Wang W, Zhang N, Liu W, Wang T, Ding X, Zhang L
Frontiers in oncology 2022;12:887068
Frontiers in oncology 2022;12:887068
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Xie W, Yu J, Yin Y, Zhang X, Zheng X, Wang X
Frontiers in oncology 2022;12:876257
Frontiers in oncology 2022;12:876257
Integrative Proteo-Genomic Analysis for Recurrent Survival Prognosis in Colon Adenocarcinoma.
Ai F, Wang W, Liu S, Zhang D, Yang Z, Liu F
Frontiers in oncology 2022;12:871568
Frontiers in oncology 2022;12:871568
A miR-137-XIAP axis contributes to the sensitivity of TRAIL-induced cell death in glioblastoma.
Geng F, Yang F, Liu F, Zhao J, Zhang R, Hu S, Zhang J, Zhang X
Frontiers in oncology 2022;12:870034
Frontiers in oncology 2022;12:870034
Establishment of a Transient and Stable Transfection System for Babesia duncani Using a Homologous Recombination Strategy.
Wang S, Li D, Chen F, Jiang W, Luo W, Zhu G, Zhao J, He L
Frontiers in cellular and infection microbiology 2022;12:844498
Frontiers in cellular and infection microbiology 2022;12:844498
Agonists Specific for κ-Opioid Receptor Induces Apoptosis of HCC Cells Through Enhanced Endoplasmic Reticulum Stress.
Tan M, Wang H, Gao C, Jiang Z, Yin Y, Xing R, Hu L, Xu J, Zhang M, Xie Y
Frontiers in oncology 2022;12:844214
Frontiers in oncology 2022;12:844214
The Novel lncRNA RP9P Promotes Colorectal Cancer Progression by Modulating miR-133a-3p/FOXQ1 Axis.
Jin Z, Liu B, Lin B, Yang R, Wu C, Xue W, Zou X, Qian J
Frontiers in oncology 2022;12:843064
Frontiers in oncology 2022;12:843064
MiR-29b-3p Inhibits Migration and Invasion of Papillary Thyroid Carcinoma by Downregulating COL1A1 and COL5A1.
Wang C, Wang Y, Fu Z, Huang W, Yu Z, Wang J, Zheng K, Zhang S, Li S, Chen J
Frontiers in oncology 2022;12:837581
Frontiers in oncology 2022;12:837581
Cyclin-Dependent Kinase Inhibitors Function as Potential Immune Regulators via Inducing Pyroptosis in Triple Negative Breast Cancer.
Xu T, Wang Z, Liu J, Wang G, Zhou D, Du Y, Li X, Xia Y, Gao Q
Frontiers in oncology 2022;12:820696
Frontiers in oncology 2022;12:820696
LncRNA SNHG1 Promotes the Progression of Pancreatic Cancer by Regulating FGFR1 Expression via Competitively Binding to miR-497.
Chen S, Guo W, Meng M, Wu D, Zhou T, Wang L, Xu J
Frontiers in oncology 2022;12:813850
Frontiers in oncology 2022;12:813850
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Zu F, Chen H, Liu Q, Zang H, Li Z, Tan X
Frontiers in oncology 2022;12:790788
Frontiers in oncology 2022;12:790788
GNG12 as A Novel Molecular Marker for the Diagnosis and Treatment of Glioma.
Liu R, Liu Z, Zhao Y, Cheng X, Liu B, Wang Y, Wang J, Lian X, Zhu Y, Gao Y
Frontiers in oncology 2022;12:726556
Frontiers in oncology 2022;12:726556
A mitochondria-related signature for predicting immune microenvironment and therapeutic response in osteosarcoma.
Zhang L, Wu S, Huang J, Shi Y, Yin Y, Cao X
Frontiers in oncology 2022;12:1085065
Frontiers in oncology 2022;12:1085065
High expression of RARG accelerates ovarian cancer progression by regulating cell proliferation.
Xiu L, Zhao Y, Li N, Zeng J, Liu J, Fu Y, Gao Q, Wu L
Frontiers in oncology 2022;12:1063031
Frontiers in oncology 2022;12:1063031
NUF2 overexpression contributes to epithelial ovarian cancer progression via ERBB3-mediated PI3K-AKT and MAPK signaling axes.
Leng R, Meng Y, Sun X, Zhao Y
Frontiers in oncology 2022;12:1057198
Frontiers in oncology 2022;12:1057198
Establishment and experimental validation of a novel cuproptosis-related gene signature for prognostic implication in cholangiocarcinoma.
Chen J, Yu X, Tong H, Tang C, Tang Z
Frontiers in oncology 2022;12:1054063
Frontiers in oncology 2022;12:1054063
BTG2 suppresses renal cell carcinoma progression through N6-methyladenosine.
Qi F, Liu W, Tan B, Zhang J, Ma Y, Cao C, Ma F, Zhu B, Yang J, Liu X
Frontiers in oncology 2022;12:1049928
Frontiers in oncology 2022;12:1049928
PUS1 is a novel biomarker for predicting poor outcomes and triple-negative status in breast cancer.
Fang Z, Shen HY, Xu Q, Zhou HL, Li L, Yang SY, Zhu Z, Tang JH
Frontiers in oncology 2022;12:1030571
Frontiers in oncology 2022;12:1030571
Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo.
Yuan X, Duan X, Li Z, Yao B, Enhejirigala, Song W, Kong Y, Wang Y, Zhang F, Liang L, Zhu S, Zhang M, Zhang C, Huang S, Fu X
Burns & trauma 2022;10:tkac035
Burns & trauma 2022;10:tkac035
IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability.
Li W, Wang Z, Wang H, Zhang J, Wang X, Xing S, Chen S
PeerJ 2022;10:e14201
PeerJ 2022;10:e14201
Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer.
Weng M, Shi C, Han H, Zhu H, Xiao Y, Guo H, Yu Z, Wu C
PeerJ 2022;10:e14042
PeerJ 2022;10:e14042
G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice.
Yun D, Zhou L, Shi J, Li X, Wu X, Sun F
PeerJ 2022;10:e13532
PeerJ 2022;10:e13532
Long noncoding RNA Gm31629 promotes bone regeneration by maintaining bone marrow mesenchymal stem cells activity.
Cai G, Xiao Y, Yang M, Guo Q, Su T, Liu Y, Jiang T, Li C
PeerJ 2022;10:e13475
PeerJ 2022;10:e13475
Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress.
Zhou X, Huang N, Hou X, Zhu L, Xie Y, Ba Z, Luo Y
PeerJ 2022;10:e13256
PeerJ 2022;10:e13256
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
Huang Z, Gao H, Qing L, Wang B, He C, Luo N, Lu C, Fan S, Gu P, Zhao H
PeerJ 2022;10:e13220
PeerJ 2022;10:e13220
ATP11A promotes EMT by regulating Numb PRR(L) in pancreatic cancer cells.
Chen L, Tang J, Sheng W, Sun J, Ma Y, Dong M
PeerJ 2022;10:e13172
PeerJ 2022;10:e13172
7,8-Dihydroxyflavone protects neurons against oxygen-glucose deprivation induced apoptosis and activates the TrkB/Akt pathway.
Zhou Q, Tang H, Bai D, Kong Y
PeerJ 2022;10:e12886
PeerJ 2022;10:e12886
Long-term environmental exposure of darkness induces hyperandrogenism in PCOS via melatonin receptor 1A and aromatase reduction.
Chu W, Li S, Geng X, Wang D, Zhai J, Lu G, Chan WY, Chen ZJ, Du Y
Frontiers in cell and developmental biology 2022;10:954186
Frontiers in cell and developmental biology 2022;10:954186
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Wang Z, Zhang P, Zhao Y, Yu F, Wang S, Liu K, Cheng X, Shi J, He Q, Xia Y, Cheng L
Frontiers in bioengineering and biotechnology 2022;10:883118
Frontiers in bioengineering and biotechnology 2022;10:883118
Inflammatory Microenvironment Accelerates Bone Marrow Mesenchymal Stem Cell Aging.
Peng X, Zhou X, Yin Y, Luo B, Liu Y, Yang C
Frontiers in bioengineering and biotechnology 2022;10:870324
Frontiers in bioengineering and biotechnology 2022;10:870324
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Feng KL, Diao N, Zhou ZW, Fang CK, Wang JN, Zhang Y, Luo R, Zhong C
Frontiers in cell and developmental biology 2022;10:850708
Frontiers in cell and developmental biology 2022;10:850708
Identification of KIF23 as a Prognostic Biomarker Associated With Progression of Clear Cell Renal Cell Carcinoma.
Wu Z, Song Y, Wu Y, Ge L, Liu Z, Du T, Zhang S, Ma L
Frontiers in cell and developmental biology 2022;10:839821
Frontiers in cell and developmental biology 2022;10:839821
Potassium Titanate Assembled Titanium Dioxide Nanotube Arrays Endow Titanium Implants Excellent Osseointegration Performance and Nerve Formation Potential.
Zhao H, Liu F, Yin Y, Wang S
Frontiers in chemistry 2022;10:839093
Frontiers in chemistry 2022;10:839093
A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia.
Shu L, Wang C, Ding Z, Tang J, Zhu Y, Wu L, Wang Z, Zhang T, Wang T, Xu Y, Sun L
Frontiers in cell and developmental biology 2022;10:837000
Frontiers in cell and developmental biology 2022;10:837000
Stimulator of Interferon Genes (STING) Promotes Staphylococcus aureus-Induced Extracellular Traps Formation via the ROS-ERK Signaling Pathway.
Liu ZZ, Chen W, Zhou CK, Ma K, Gao Y, Yang YJ
Frontiers in cell and developmental biology 2022;10:836880
Frontiers in cell and developmental biology 2022;10:836880
HIF-1α Regulates Osteogenesis of Periosteum-Derived Stem Cells Under Hypoxia Conditions via Modulating POSTN Expression.
Zhuang Y, Zhao Z, Cheng M, Li M, Si J, Lin K, Yu H
Frontiers in cell and developmental biology 2022;10:836285
Frontiers in cell and developmental biology 2022;10:836285
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Peng X, Ding C, Zhao Y, Hao M, Liu W, Yang M, Xiao F, Zheng Y
Frontiers in bioengineering and biotechnology 2022;10:831007
Frontiers in bioengineering and biotechnology 2022;10:831007
Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis.
Hu Q, Wei W, Wu D, Huang F, Li M, Li W, Yin J, Peng Y, Lu Y, Zhao Q, Liu L
Frontiers in cell and developmental biology 2022;10:810327
Frontiers in cell and developmental biology 2022;10:810327
Tetrahydropalmatine induces the polarization of M1 macrophages to M2 to relieve limb ischemia-reperfusion-induced lung injury via inhibiting the TLR4/NF-κB/NLRP3 signaling pathway.
Wen H, Lu D, Chen H, Zhu Y, Xie Q, Zhang Z, Wu Z
Drug development research 2022 Sep;83(6):1362-1372
Drug development research 2022 Sep;83(6):1362-1372
Phospholipase A/acyltransferase 4 is a prognostic biomarker and correlated with immune infiltrates in pancreatic cancer.
Li TH, Wang YY, Zhao BB, Qin C, Li ZR, Wang WB
Heliyon 2022 Sep;8(9):e10416
Heliyon 2022 Sep;8(9):e10416
JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia.
Qi D, Wang J, Zhao Y, Yang Y, Wang Y, Wang H, Wang L, Wang Z, Xu X, Hu Z
Leukemia & lymphoma 2022 Sep;63(9):2149-2160
Leukemia & lymphoma 2022 Sep;63(9):2149-2160
Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway.
Zhao L, Lan Z, Peng L, Wan L, Liu D, Tan X, Tang C, Chen G, Liu H
Cell proliferation 2022 Sep;55(9):e13278
Cell proliferation 2022 Sep;55(9):e13278
HIF‑1α and MBP1 are associated with the progression of breast cancer cells by repressing β‑catenin transcription.
Zhuang Y, Li X, Zhan P, Pi G, Wen G
Oncology reports 2022 Sep;48(3)
Oncology reports 2022 Sep;48(3)
Establishment and application of a human osteosarcoma U-2OS cell line that can stably express Cas9 protein.
Zhou Y, Li Y, Zhang Y, Yi Z, Jiang M
Molecular and cellular biochemistry 2022 Sep;477(9):2183-2191
Molecular and cellular biochemistry 2022 Sep;477(9):2183-2191
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
Zhai J, Li S, Sen S, Vallvé-Juanico J, Irwin JC, Vo KC, Wan J, Du Y, Chen ZJ, Giudice LC
Reproductive biomedicine online 2022 Sep;45(3):519-530
Reproductive biomedicine online 2022 Sep;45(3):519-530
Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway.
Yang X, Yang P, Zhang J, Yang Y, Xiong M, Shi F, Li N, Jin Y
Environmental toxicology 2022 Sep;37(9):2291-2301
Environmental toxicology 2022 Sep;37(9):2291-2301
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
Dai Y, Yu T, Yu C, Lu T, Zhou L, Cheng C, Ni H
Environmental toxicology 2022 Sep;37(9):2133-2142
Environmental toxicology 2022 Sep;37(9):2133-2142
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhu C, Tian M, Liu N, Ma L, Lan X, Yang J, Du J, Ma H, Li Y, Zheng P, Yu J, Peng X
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
LINC01140 regulates osteosarcoma proliferation and invasion by targeting the miR-139-5p/HOXA9 axis.
Zhang S, Chen R
Biochemistry and biophysics reports 2022 Sep;31:101301
Biochemistry and biophysics reports 2022 Sep;31:101301
Overexpression of MCAM induced by SMYD2-H3K36me2 in breast cancer stem cell properties.
Li X, Wang Y, Zhang Y, Liu B
Breast cancer (Tokyo, Japan) 2022 Sep;29(5):854-868
Breast cancer (Tokyo, Japan) 2022 Sep;29(5):854-868
E3 ubiquitin ligase RNF6 promotes antiviral immune responses through enhancing the expression of interferon stimulated genes in myeloid cells.
Sun W, Hua X, Gu Y, Xu Q, Zhu S, Lv T, Song Y
Clinical immunology (Orlando, Fla.) 2022 Sep;242:109099
Clinical immunology (Orlando, Fla.) 2022 Sep;242:109099
Protective effects of budesonide on LPS-induced podocyte injury by modulating macrophage M1/M2 polarization: Evidence from in vitro and in silico studies.
Zhang X, Wang G, Shen D, Feng Y, Zhang Y, Zhang C, Li Y, Liao H
Experimental and therapeutic medicine 2022 Sep;24(3):589
Experimental and therapeutic medicine 2022 Sep;24(3):589
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Wang W, Jing X, Du T, Ren J, Liu X, Chen F, Shao Y, Sun S, Yang G, Cui X
Free radical biology & medicine 2022 Sep;190:234-246
Free radical biology & medicine 2022 Sep;190:234-246
TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus.
Zhao L, Liu Q, Huang J, Lu Y, Zhao Y, Ping J
PLoS pathogens 2022 Sep;18(9):e1010835
PLoS pathogens 2022 Sep;18(9):e1010835
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Zhang S, Xie Y, Yan F, Zhang Y, Yang Z, Chen Z, Zhao Y, Huang Z, Cai L, Deng Z
Autophagy 2022 Sep;18(9):2229-2245
Autophagy 2022 Sep;18(9):2229-2245
Lactate inhibits osteogenic differentiation of human periodontal ligament stem cells via autophagy through the MCT1-mTOR signaling pathway.
Luo Y, Gou H, Chen X, Li L, Wang X, Xu Y
Bone 2022 Sep;162:116444
Bone 2022 Sep;162:116444
Hylocereus undatus flower extract suppresses OVA-induced allergic asthma in BALb/c mice by reducing airway inflammation and modulating gut microbiota.
Liao W, Liu W, Yan Y, Li L, Tong J, Huang Y, Guo S, Jiang W, Fu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113476
Complement factor B inhibitor LNP023 improves lupus nephritis in MRL/lpr mice.
Chen K, Deng Y, Shang S, Tang L, Li Q, Bai X, Chen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113433
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113433
NLRP3 inflammasome contributes to endothelial dysfunction in angiotensin II-induced hypertension in mice.
Li X, Zhang Z, Luo M, Cheng Z, Wang R, Liu Q, Lv D, Yan J, Shang F, Luo S, Xia Y
Microvascular research 2022 Sep;143:104384
Microvascular research 2022 Sep;143:104384
Increased IRF9-STAT2 Signaling Leads to Adaptive Resistance toward Targeted Therapy in Melanoma by Restraining GSDME-Dependent Pyroptosis.
Wang D, Fu Z, Gao L, Zeng J, Xiang Y, Zhou L, Tong X, Wang XQ, Lu J
The Journal of investigative dermatology 2022 Sep;142(9):2476-2487.e9
The Journal of investigative dermatology 2022 Sep;142(9):2476-2487.e9
The pH sensor and ion binding of NhaD Na(+) /H(+) antiporter from IT superfamily.
Lv P, Li Y, Wang R, Zhang Y, Wang W, Liu Y, Shang Y, Su D, Wang W, Yang C
Molecular microbiology 2022 Sep;118(3):244-257
Molecular microbiology 2022 Sep;118(3):244-257
FEK self-assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening.
He T, Qiao S, Ma C, Peng Z, Wu Z, Ma C, Han L, Deng Q, Zhang T, Zhu Y, Pan G
Journal of biomedical materials research. Part B, Applied biomaterials 2022 Sep;110(9):2015-2027
Journal of biomedical materials research. Part B, Applied biomaterials 2022 Sep;110(9):2015-2027
Shexiang Baoxin Pill attenuates myocardial ischemia/reperfusion injury by activating autophagy via modulating the ceRNA-Map3k8 pathway.
Yu YW, Liu S, Zhou YY, Huang KY, Wu BS, Lin ZH, Zhu CX, Xue YJ, Ji KT
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154336
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154336
Novel mutations of PMFBP1 in a man with acephalic spermatozoa defects.
Nie H, Tang Y, Zhang X, Tan Y, Qin W
Molecular genetics & genomic medicine 2022 Sep;10(9):e2020
Molecular genetics & genomic medicine 2022 Sep;10(9):e2020
Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37.
Qin S, Yuan Y, Huang X, Tan Z, Hu X, Liu H, Pu Y, Ding YQ, Su Z, He C
Nucleic acids research 2022 Sep 9;50(16):9319-9338
Nucleic acids research 2022 Sep 9;50(16):9319-9338
1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway.
Fan Y, Lu J, Yu Z, Qu X, Guan S
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10847-10857
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10847-10857
ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli.
Huang W, Liu H, Tan W, Wang J
Medical oncology (Northwood, London, England) 2022 Sep 7;39(12):188
Medical oncology (Northwood, London, England) 2022 Sep 7;39(12):188
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model.
Lu Y, Zhang J, Zeng F, Wang P, Guo X, Wang H, Qin Z, Tao T
Journal of neuroinflammation 2022 Sep 7;19(1):221
Journal of neuroinflammation 2022 Sep 7;19(1):221
PIM1 promotes hepatic conversion by suppressing reprogramming-induced ferroptosis and cell cycle arrest.
Yuan Y, Wang C, Zhuang X, Lin S, Luo M, Deng W, Zhou J, Liu L, Mao L, Peng W, Chen J, Wang Q, Shu Y, Xue Y, Huang P
Nature communications 2022 Sep 6;13(1):5237
Nature communications 2022 Sep 6;13(1):5237
Multimodal cotranslational interactions direct assembly of the human multi-tRNA synthetase complex.
Khan K, Long B, Gogonea V, Deshpande GM, Vasu K, Fox PL
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 6;119(36):e2205669119
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 6;119(36):e2205669119
HDAC3 of dorsal hippocampus induces postoperative cognitive dysfunction in aged mice.
Yang L, Hao JR, Gao Y, Yang X, Shen XR, Wang HY, Sun N, Gao C
Behavioural brain research 2022 Sep 5;433:114002
Behavioural brain research 2022 Sep 5;433:114002
Hawk Tea Flavonoids as Natural Hepatoprotective Agents Alleviate Acute Liver Damage by Reshaping the Intestinal Microbiota and Modulating the Nrf2 and NF-κB Signaling Pathways.
Xu T, Hu S, Liu Y, Sun K, Luo L, Zeng L
Nutrients 2022 Sep 5;14(17)
Nutrients 2022 Sep 5;14(17)
MicroRNA-20a-5p regulates the epithelial-mesenchymal transition of human hepatocellular carcinoma by targeting RUNX3.
Wang X, Wei P, Yang L, Liu F, Tong X, Yang X, Su L
Chinese medical journal 2022 Sep 5;135(17):2089-2097
Chinese medical journal 2022 Sep 5;135(17):2089-2097
Emodin regulates the autophagy via the miR-371a-5p/PTEN axis to inhibit hepatic malignancy.
Wu W, Lu P, Huang Y, Zhu Z, Li C, Liu Y
Biochemical and biophysical research communications 2022 Sep 3;619:1-8
Biochemical and biophysical research communications 2022 Sep 3;619:1-8
Effects of Let-7c on the processing of hepatitis B virus associated liver diseases.
Zhang L, Jiang X, Wang G, Kanda T, Yokosuka O, Zhai C, Zhang L, Liu P, Zhao Z, Li Z
Infectious agents and cancer 2022 Sep 3;17(1):46
Infectious agents and cancer 2022 Sep 3;17(1):46
Expression and Prognostic Value of Chromobox Family Proteins in Esophageal Cancer.
Liu J, Shen H, Chen X, Ding Y, Wang H, Xu N, Teng L
Genes 2022 Sep 3;13(9)
Genes 2022 Sep 3;13(9)
Boosting cisplatin chemotherapy by nanomotor-enhanced tumor penetration and DNA adducts formation.
Xu L, Zhang K, Ma X, Li Y, Jin Y, Liang C, Wang Y, Duan W, Zhang H, Zhang Z, Shi J, Liu J, Wang Y, Li W
Journal of nanobiotechnology 2022 Sep 29;20(1):429
Journal of nanobiotechnology 2022 Sep 29;20(1):429
Transmissible Gastroenteritis Virus Infection Promotes the Self-Renewal of Porcine Intestinal Stem Cells via Wnt/β-Catenin Pathway.
Yang N, Zhang Y, Fu Y, Li Y, Yang S, Chen J, Liu G
Journal of virology 2022 Sep 28;96(18):e0096222
Journal of virology 2022 Sep 28;96(18):e0096222
Duck Tembusu Virus Inhibits Type I Interferon Production through the JOSD1-SOCS1-IRF7 Negative-Feedback Regulation Pathway.
Huang S, Huang J, Cui M, Wu X, Wang M, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Yu Y, Tian B, Liu Y, Zhang L, Yin Z, Jing B, Chen X, Cheng A, Jia R
Journal of virology 2022 Sep 28;96(18):e0093022
Journal of virology 2022 Sep 28;96(18):e0093022
Identification of Host Factors Differentially Induced by Clinically Diverse Strains of Tick-Borne Encephalitis Virus.
Goonawardane N, Upstone L, Harris M, Jones IM
Journal of virology 2022 Sep 28;96(18):e0081822
Journal of virology 2022 Sep 28;96(18):e0081822
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.
Wang X, Liu Y, Xue C, Hu Y, Zhao Y, Cai K, Li M, Luo Z
Nature communications 2022 Sep 28;13(1):5685
Nature communications 2022 Sep 28;13(1):5685
Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy.
Yu Q, Gong X, Tong Y, Wang M, Duan K, Zhang X, Ge F, Yu X, Li S
Nature communications 2022 Sep 27;13(1):5675
Nature communications 2022 Sep 27;13(1):5675
ACACB is a novel metabolism-related biomarker in the prediction of response to cetuximab therapy inmetastatic colorectal cancer.
Hong HJ, Shao Y, Zhang S, Yang G, Jia H, Yang X, Huang L, Li S, Aikemu B, Zhang L, Ma J, Zang L, Sun J, Zheng M
Acta biochimica et biophysica Sinica 2022 Sep 25;54(11):1671-1683
Acta biochimica et biophysica Sinica 2022 Sep 25;54(11):1671-1683
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Zhao X, Xia Z, Wang Z, Zhou M, Qiu X, Wang C, Xu T, Fang Q, Ming Z, Dong H
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology.
Zhang Y, Lv W, Li H, Dong T, Wu H, Su C, Shu H, Nie F
Cancer cell international 2022 Sep 25;22(1):293
Cancer cell international 2022 Sep 25;22(1):293
A novel 2B4 receptor leads to worse pregnancy outcomes by facilitating TNF-α and IFN-γ production in dNK cells during Toxoplasma gondii infection.
Xu X, Zheng G, Ren Y, He X, Peng B, Hu X, Liu W
Parasites & vectors 2022 Sep 24;15(1):337
Parasites & vectors 2022 Sep 24;15(1):337
Co-Targeting ErbB Receptors and the PI3K/AKT Axis in Androgen-Independent Taxane-Sensitive and Taxane-Resistant Human Prostate Cancer Cells.
Adediran S, Wang L, Khan MA, Guang W, Fan X, Dan H, Qi J, Jay SM, Carrier F, Hussain A
Cancers 2022 Sep 23;14(19)
Cancers 2022 Sep 23;14(19)
Realgar Alleviated Neuroinflammation Induced by High Protein and High Calorie Diet in Rats via the Microbiota-Gut-Brain Axis.
Feng C, Li A, Yin C, Wang S, Jin W, Liu Y, Huo T, Jiang H
Nutrients 2022 Sep 23;14(19)
Nutrients 2022 Sep 23;14(19)
Effects of Moderate-Intensity Continuous Training and High-Intensity Interval Training on Testicular Oxidative Stress, Apoptosis and m6A Methylation in Obese Male Mice.
Xu Z, Qin Y, Lv B, Tian Z, Zhang B
Antioxidants (Basel, Switzerland) 2022 Sep 21;11(10)
Antioxidants (Basel, Switzerland) 2022 Sep 21;11(10)
Effects of plant-based medicinal food on postoperative recurrence and lung metastasis of gastric cancer regulated by Wnt/β-catenin-EMT signaling pathway and VEGF-C/D-VEGFR-3 cascade in a mouse model.
Tian L, Chen X, Cao L, Zhang L, Chen J
BMC complementary medicine and therapies 2022 Sep 2;22(1):233
BMC complementary medicine and therapies 2022 Sep 2;22(1):233
The Immune Subtypes and Landscape of Advanced-Stage Ovarian Cancer.
Zhang M, Shi M, Yu Y, Sang J, Wang H, Shi J, Duan P, Ge R
Vaccines 2022 Sep 2;10(9)
Vaccines 2022 Sep 2;10(9)
The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma.
Shi Y, Cui X, Jiang T, Pan Y, Lin Y, Feng X, Ding Z, Yang C, Tan Y, Wang H, Dong L
Cell death & disease 2022 Sep 19;13(9):799
Cell death & disease 2022 Sep 19;13(9):799
Isosteviol sodium attenuates high fat/high cholesterol-induced myocardial dysfunction by regulating the Sirt1/AMPK pathway.
Mei Y, Hu H, Deng L, Sun X, Tan W
Biochemical and biophysical research communications 2022 Sep 17;621:80-87
Biochemical and biophysical research communications 2022 Sep 17;621:80-87
R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization.
Myers B, Sechrest ER, Hamner G, Motipally SI, Murphy J, Kolandaivelu S
International journal of molecular sciences 2022 Sep 16;23(18)
International journal of molecular sciences 2022 Sep 16;23(18)
Proteomic analysis reveals that ACSL4 activation during reflux esophagitis contributes to ferroptosis-mediated esophageal mucosal damage.
Liu S, Tang Y, Liu L, Yang L, Li P, Liu X, Yin H
European journal of pharmacology 2022 Sep 15;931:175175
European journal of pharmacology 2022 Sep 15;931:175175
Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.
Kang JB, Chen L, Leng XJ, Wang JJ, Cheng Y, Wu SH, Ma YY, Yang LJ, Cao YH, Yang X, Tong ZJ, Wu JZ, Wang YB, Zhou H, Liu JC, Ding N, Dai WC, Yu YC, Xue X, Sun SL, Dai XB, Chang L, Wang XL, Li NG, Shi ZH
Bioorganic & medicinal chemistry 2022 Sep 15;70:116937
Bioorganic & medicinal chemistry 2022 Sep 15;70:116937
Study of differential proteomics in granulosa cells of premature ovarian insufficiency (POI) and the roles and mechanism of RAC1 in granulosa cells.
Zhang QY, Li X, Zhou XY, Li Y, Zhang J, Zhang XF, Liu YD, Chen YX, Wu XM, Ma LZ, Chen X, Chen SL
Molecular and cellular endocrinology 2022 Sep 15;555:111719
Molecular and cellular endocrinology 2022 Sep 15;555:111719
Small extracellular vesicles derived from hypoxic mesenchymal stem cells promote vascularized bone regeneration through the miR-210-3p/EFNA3/PI3K pathway.
Zhuang Y, Cheng M, Li M, Cui J, Huang J, Zhang C, Si J, Lin K, Yu H
Acta biomaterialia 2022 Sep 15;150:413-426
Acta biomaterialia 2022 Sep 15;150:413-426
African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.
Li L, Fu J, Li J, Guo S, Chen Q, Zhang Y, Liu Z, Tan C, Chen H, Wang X
Journal of virology 2022 Sep 14;96(17):e0094422
Journal of virology 2022 Sep 14;96(17):e0094422
Sinomenine Hydrochloride Promotes TSHR-Dependent Redifferentiation in Papillary Thyroid Cancer.
Zhang J, Zhao A, Jia X, Li X, Liang Y, Liu Y, Xie X, Qu X, Wang Q, Zhang Y, Gao R, Yu Y, Yang A
International journal of molecular sciences 2022 Sep 14;23(18)
International journal of molecular sciences 2022 Sep 14;23(18)
Construction of tandem diabody (IL-6/CD20)-secreting human umbilical cord mesenchymal stem cells and its experimental treatment on diffuse large B cell lymphoma.
Zhang J, Zhong M, Zhong W, Lan Y, Yuan Z, Duan Y, Wei Y
Stem cell research & therapy 2022 Sep 14;13(1):473
Stem cell research & therapy 2022 Sep 14;13(1):473
NMR-Based Metabolomic Analysis for the Effects of Trimethylamine N-Oxide Treatment on C2C12 Myoblasts under Oxidative Stress.
Zou H, Huang C, Zhou L, Lu R, Zhang Y, Lin D
Biomolecules 2022 Sep 13;12(9)
Biomolecules 2022 Sep 13;12(9)
Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy.
Yan W, Zheng L, Xu X, Hao Z, Zhang Y, Lu J, Sun Z, Dai J, Shi D, Guo B, Jiang Q
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 13;119(37):e2203557119
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 13;119(37):e2203557119
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas.
Tu Z, Ji Q, Han Q, Long X, Li J, Wu L, Huang K, Zhu X
BMC cancer 2022 Sep 12;22(1):973
BMC cancer 2022 Sep 12;22(1):973
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
Li H, Li J, Zhang T, Xie X, Gong J
Biochemical and biophysical research communications 2022 Sep 10;620:56-62
Biochemical and biophysical research communications 2022 Sep 10;620:56-62
RO4929097, a Selective γ-Secretase Inhibitor, Inhibits Subretinal Fibrosis Via Suppressing Notch and ERK1/2 Signaling in Laser-Induced Mouse Model.
Zhang C, Qin S, Xie H, Qiu Q, Wang H, Zhang J, Luo D, Zhang J
Investigative ophthalmology & visual science 2022 Sep 1;63(10):14
Investigative ophthalmology & visual science 2022 Sep 1;63(10):14
PLIN2 promotes HCC cells proliferation by inhibiting the degradation of HIF1α.
Liu W, Liu X, Liu Y, Ling T, Chen D, Otkur W, Zhao H, Ma M, Ma K, Dong B, Yang Z, Piao HL, Liang R, Dong C
Experimental cell research 2022 Sep 1;418(1):113244
Experimental cell research 2022 Sep 1;418(1):113244
Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells.
Flamand MN, Ke K, Tamming R, Meyer KD
Genes & development 2022 Sep 1;36(17-18):1002-1015
Genes & development 2022 Sep 1;36(17-18):1002-1015
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
Xue L, Li X, Zhu X, Zhang J, Zhou S, Tang W, Chen D, Chen Y, Dai J, Wu M, Wu M, Wang S
Ecotoxicology and environmental safety 2022 Sep 1;242:113859
Ecotoxicology and environmental safety 2022 Sep 1;242:113859
The Prevention and Reversal of a Phenytoin-Resistant Model by N-acetylcysteine Therapy Involves the Nrf2/P-Glycoprotein Pathway at the Blood-Brain Barrier.
Liu Q, Wang Y, Tan D, Liu Y, Zhang P, Ma L, Liang M, Chen Y
Journal of molecular neuroscience : MN 2022 Oct;72(10):2125-2135
Journal of molecular neuroscience : MN 2022 Oct;72(10):2125-2135
Growth hormone inhibits adipogenic differentiation and induces browning in bovine subcutaneous adipocytes.
Li T, Bai H, Fang H, Yang L, Yan P
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2022 Oct;66:101498
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2022 Oct;66:101498
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2.
Qian C, Wang Y, Ji Y, Chen D, Wang C, Zhang G, Wang Y
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia.
He Y, Chang Y, Peng Y, Zhu J, Liu K, Chen J, Wu Y, Ji Z, Lin Z, Wang S, Gupta S, Zang N, Pan S, Huang K
Molecular neurobiology 2022 Oct;59(10):6590-6607
Molecular neurobiology 2022 Oct;59(10):6590-6607
Hippocampal Inhibitory Synapsis Deficits Induced by α5-Containing GABA(A) Receptors Mediate Chronic Neuropathic Pain-Related Cognitive Impairment.
Cai X, Qiu L, Wang C, Yang H, Zhou Z, Mao M, Zhu Y, Wen Y, Cai W, Zhu W, Sun J
Molecular neurobiology 2022 Oct;59(10):6049-6061
Molecular neurobiology 2022 Oct;59(10):6049-6061
Expression patterns and correlation analyses of muscle-specific genes in the process of sheep myoblast differentiation.
Wang H, Dou M, Li J, Cao P, Li J, Guo T, Zhao D, Khan A, Li Y, Li B, Qin J, Du R
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):798-809
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):798-809
Ferroportin-dependent ferroptosis induced by ellagic acid retards liver fibrosis by impairing the SNARE complexes formation.
Li L, Wang K, Jia R, Xie J, Ma L, Hao Z, Zhang W, Mo J, Ren F
Redox biology 2022 Oct;56:102435
Redox biology 2022 Oct;56:102435
TGF-β1 peptide-based inhibitor P144 ameliorates renal fibrosis after ischemia-reperfusion injury by modulating alternatively activated macrophages.
Li D, Zhang J, Yuan S, Wang C, Chang J, Tong Y, Liu R, Sang T, Li L, Li J, Ouyang Q, Chen X
Cell proliferation 2022 Oct;55(10):e13299
Cell proliferation 2022 Oct;55(10):e13299
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.
Pan C, Qin H, Jin H, Chen W, Guo H, Han X
Toxicology 2022 Oct;480:153326
Toxicology 2022 Oct;480:153326
Comparison of DNA stability and its related genes of neurons derived from induced pluripotent stem cells and primary retinal neurons.
Yu N, Qiu J, Li K, Luo Q, Liu X, Yang Y, Jiang Z, He S, He A, Chen S, Chen X, Li Y, Ge J, Zhuang J, Yu K
Cell biology international 2022 Oct;46(10):1625-1636
Cell biology international 2022 Oct;46(10):1625-1636
Dapagliflozin Alleviates Coxsackievirus B3-induced Acute Viral Myocarditis by Regulating the Macrophage Polarization Through Stat3-related Pathways.
Yan P, Song X, Tran J, Zhou R, Cao X, Zhao G, Yuan H
Inflammation 2022 Oct;45(5):2078-2090
Inflammation 2022 Oct;45(5):2078-2090
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Zhao X, Shu D, Sun W, Si S, Ran W, Guo B, Cui L
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Circadian clock gene BMAL1 inhibits the proliferation and tumor-formation ability of nasopharyngeal carcinoma cells and increases the sensitivity of radiotherapy.
Zhao C, Meng X, Li Y, Liu L, He Q, Jiang J, Chen Y, Li X, Li Y, Tang Y, Zhou D, Zhou J, Jin F
Chronobiology international 2022 Oct;39(10):1340-1351
Chronobiology international 2022 Oct;39(10):1340-1351
Rottlerin plays an antiviral role at early and late steps of Zika virus infection.
Zhou S, Lin Q, Huang C, Luo X, Tian X, Liu C, Zhang P
Virologica Sinica 2022 Oct;37(5):685-694
Virologica Sinica 2022 Oct;37(5):685-694
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Guan S, Zhang R, Zhao Y, Meng Z, Lu J
Environmental toxicology 2022 Oct;37(10):2515-2528
Environmental toxicology 2022 Oct;37(10):2515-2528
The influence of different proton pump inhibitors and potassium-competitive acid blockers on indomethacin-induced small intestinal injury.
Li K, Cheng X, Jin R, Han T, Li J
Journal of gastroenterology and hepatology 2022 Oct;37(10):1935-1945
Journal of gastroenterology and hepatology 2022 Oct;37(10):1935-1945
ICAT promotes colorectal cancer metastasis via binding to JUP and activating the NF-κB signaling pathway.
Wang Z, Hu J, Chen J, Zhang J, Li W, Tian Y, Liu H, Yang X
Journal of clinical laboratory analysis 2022 Oct;36(10):e24678
Journal of clinical laboratory analysis 2022 Oct;36(10):e24678
A single-beam of light priming the immune responses and boosting cancer photoimmunotherapy.
Sun Y, Han R, Wang J, Qin Y, Ren Z, Feng X, Liu Q, Wang X
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:734-747
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:734-747
Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway.
Zhou S, Li P, Qin L, Huang S, Dang N
Experimental dermatology 2022 Oct;31(10):1563-1578
Experimental dermatology 2022 Oct;31(10):1563-1578
TSP1 promotes fibroblast proliferation and extracellular matrix deposition via the IL6/JAK2/STAT3 signalling pathway in keloids.
Feng QL, Gu JJ, Chen JY, Zheng WY, Pan HH, Xu XY, Deng CC, Yang B
Experimental dermatology 2022 Oct;31(10):1533-1542
Experimental dermatology 2022 Oct;31(10):1533-1542
Peptide OM-LV20 protects astrocytes against oxidative stress via the 'PAC1R/JNK/TPH1' axis.
Yin S, Pang A, Liu C, Li Y, Liu N, Li S, Li C, Sun H, Fu Z, Wang Y, Zhang Y, Yang M, Sun J, Wang Y, Yang X
The Journal of biological chemistry 2022 Oct;298(10):102429
The Journal of biological chemistry 2022 Oct;298(10):102429
Downregulation of EZH2 in Trophoblasts Induces Decidual M1 Macrophage Polarization: a Potential Cause of Recurrent Spontaneous Abortion.
Shang Y, Wu S, Li S, Qin X, Chen J, Ding J, Yang J
Reproductive sciences (Thousand Oaks, Calif.) 2022 Oct;29(10):2820-2828
Reproductive sciences (Thousand Oaks, Calif.) 2022 Oct;29(10):2820-2828
The HN1/HMGB1 axis promotes the proliferation and metastasis of hepatocellular carcinoma and attenuates the chemosensitivity to oxaliplatin.
Wang R, Fu Y, Yao M, Cui X, Zhao Y, Lu X, Li Y, Lin Y, He S
The FEBS journal 2022 Oct;289(20):6400-6419
The FEBS journal 2022 Oct;289(20):6400-6419
SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.
Chen S, Li QH, Chen X, Bao HJ, Wu W, Shen F, Lu BF, Jiang RQ, Zong ZH, Zhao Y
Journal of cellular and molecular medicine 2022 Oct;26(20):5150-5164
Journal of cellular and molecular medicine 2022 Oct;26(20):5150-5164
Syce1 and Syce3 regulate testosterone and dihydrotestosterone synthesis via steroidogenic pathways in mouse Sertoli and Leydig cells.
Wang Q, Yan Q, Nan J, Wang J, Zhang Y, Zhao X
The Journal of steroid biochemistry and molecular biology 2022 Oct;223:106135
The Journal of steroid biochemistry and molecular biology 2022 Oct;223:106135
The SIRT1 activator SRT2104 promotes BMP9-induced osteogenic and angiogenic differentiation in mesenchymal stem cells.
Lu Y, Ma ZX, Deng R, Jiang HT, Chu L, Deng ZL
Mechanisms of ageing and development 2022 Oct;207:111724
Mechanisms of ageing and development 2022 Oct;207:111724
Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin α7 is counteracted by TBK1-p62 axis-mediated autophagy.
Wang X, Jiang L, Wang G, Shi W, Hu Y, Wang B, Zeng X, Tian G, Deng G, Shi J, Liu L, Li C, Chen H
Cellular & molecular immunology 2022 Oct;19(10):1168-1184
Cellular & molecular immunology 2022 Oct;19(10):1168-1184
Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid-β oligomers.
Zhou J, Zhang Z, Yang Y, Liao F, Zhou P, Wang Y, Zhang H, Jiang H, Alinejad T, Shan G, Wu S
Journal of neurochemistry 2022 Oct;163(1):8-25
Journal of neurochemistry 2022 Oct;163(1):8-25
The anti-inflammatory effect of vasoactive peptides from soybean protein hydrolysates by mediating serum extracellular vesicles-derived miRNA-19b/CYLD/TRAF6 axis in the vascular microenvironment of SHRs.
Song T, Zhou M, Li W, Lv M, Zheng L, Zhao M
Food research international (Ottawa, Ont.) 2022 Oct;160:111742
Food research international (Ottawa, Ont.) 2022 Oct;160:111742
Black mulberry (Morus nigra) fruit extract alleviated AD-Like symptoms induced by toxic Aβ protein in transgenic Caenorhabditis elegans via insulin DAF-16 signaling pathway.
Wang E, Wang N, Zou Y, Fahim M, Zhou Y, Yang H, Liu Y, Li H
Food research international (Ottawa, Ont.) 2022 Oct;160:111696
Food research international (Ottawa, Ont.) 2022 Oct;160:111696
Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway.
Fu C, Qiu Z, Huang Y, Lin Q, Jin L, Tu H, Ye J, Zheng C, Zhong W, Ma D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113551
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113551
Electroacupuncture at PC6 (Neiguan) Attenuates Angina Pectoris in Rats with Myocardial Ischemia-Reperfusion Injury Through Regulating the Alternative Splicing of the Major Inhibitory Neurotransmitter Receptor GABRG2.
Qi W, Fu H, Luo X, Ren Y, Liu X, Dai H, Zheng Q, Liang F
Journal of cardiovascular translational research 2022 Oct;15(5):1176-1191
Journal of cardiovascular translational research 2022 Oct;15(5):1176-1191
Long non-coding RNA VAL facilitates PKM2 enzymatic activity to promote glycolysis and malignancy of gastric cancer.
Dai T, Zhang X, Zhou X, Hu X, Huang X, Xing F, Tian H, Li Y
Clinical and translational medicine 2022 Oct;12(10):e1088
Clinical and translational medicine 2022 Oct;12(10):e1088
Emodin attenuates severe acute pancreatitis-associated acute lung injury by suppressing pancreatic exosome-mediated alveolar macrophage activation.
Hu Q, Yao J, Wu X, Li J, Li G, Tang W, Liu J, Wan M
Acta pharmaceutica Sinica. B 2022 Oct;12(10):3986-4003
Acta pharmaceutica Sinica. B 2022 Oct;12(10):3986-4003
Frequently expressed glypican-3 as a promising novel therapeutic target for osteosarcomas.
Nie JH, Yang T, Li H, Li S, Li TT, Ye HS, Lu MD, Chu X, Zhong GQ, Zhou JL, Wu ML, Zhang Y, Liu J
Cancer science 2022 Oct;113(10):3618-3632
Cancer science 2022 Oct;113(10):3618-3632
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Cai R, Wang P, Zhao X, Lu X, Deng R, Wang X, Hong C, Lin J
Cancer science 2022 Oct;113(10):3593-3607
Cancer science 2022 Oct;113(10):3593-3607
Investigation into the anti-airway inflammatory role of the PI3Kγ inhibitor JN-PK1: An in vitro and in vivo study.
Xiong W, Jia L, Liang J, Cai Y, Chen Y, Nie Y, Jin J, Zhu J
International immunopharmacology 2022 Oct;111:109102
International immunopharmacology 2022 Oct;111:109102
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
Lin H, Ma X, Yang X, Chen Q, Wen Z, Yang M, Fu J, Yin T, Lu G, Qi J, Han H, Yang Y
International immunopharmacology 2022 Oct;111:109097
International immunopharmacology 2022 Oct;111:109097
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
Zheng Z, Lei C, Liu H, Jiang M, Zhou Z, Zhao Y, Yu CY, Wei H
Advanced healthcare materials 2022 Oct;11(19):e2200990
Advanced healthcare materials 2022 Oct;11(19):e2200990
Investigation of novel de novo KCNC2 variants causing severe developmental and early-onset epileptic encephalopathy.
Li L, Liu Z, Yang H, Li Y, Zeng Q, Chen L, Liu Y, Chen Y, Zhu F, Cao D, Hu J, Shen X
Seizure 2022 Oct;101:218-224
Seizure 2022 Oct;101:218-224
The propofol-induced mitochondrial damage in fetal rat hippocampal neurons via the AMPK/P53 signaling pathway.
Xiao F, Qin Y, Chen J, Li C, Qin Y, Wei Y, Xie Y
Annals of translational medicine 2022 Oct;10(20):1106
Annals of translational medicine 2022 Oct;10(20):1106
Nobiletin Prevents D-Galactose-Induced C2C12 Cell Aging by Improving Mitochondrial Function.
Wang HH, Sun YN, Qu TQ, Sang XQ, Zhou LM, Li YX, Ren FZ
International journal of molecular sciences 2022 Oct 8;23(19)
International journal of molecular sciences 2022 Oct 8;23(19)
ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer.
Yu P, Luo S, Cai J, Li J, Peng C
Aging 2022 Oct 8;14(19):7941-7958
Aging 2022 Oct 8;14(19):7941-7958
Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice.
Xu RC, Miao WT, Xu JY, Xu WX, Liu MR, Ding ST, Jian YX, Lei YH, Yan N, Liu HD
Nutrients 2022 Oct 7;14(19)
Nutrients 2022 Oct 7;14(19)
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cui X, Pei X, Wang H, Feng P, Qin H, Liu S, Yan Q, Liu J
Cells 2022 Oct 6;11(19)
Cells 2022 Oct 6;11(19)
HDAC1 in the Ovarian Granulosa Cells of Tan Sheep Improves Cumulus Cell Expansion and Oocyte Maturation Independently of the EGF-like Growth Factors.
Xu Y, Fan S, Liu Y, Shi J, Xie X, Wang X, Wang C, Liu X, Xia G
Biology 2022 Oct 6;11(10)
Biology 2022 Oct 6;11(10)
Transcriptomic Analysis Reveals Lactobacillus reuteri Alleviating Alcohol-Induced Liver Injury in Mice by Enhancing the Farnesoid X Receptor Signaling Pathway.
Cheng Y, Xiang X, Liu C, Cai T, Li T, Chen Y, Bai J, Shi H, Zheng T, Huang M, Fu W
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12550-12564
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12550-12564
Haizao Yuhu decoctions including three species of glycyrrhiza protected against propylthiouracil-induced goiter with hypothyroidism in rats via the AMPK/mTOR pathway.
Li N, Li M, Xiu L, Liao W, Ren Y, Liu H, Chen S, Chen F, Yu X, Fan A, Huo M, He J, Zhong G
Journal of ethnopharmacology 2022 Oct 5;296:115443
Journal of ethnopharmacology 2022 Oct 5;296:115443
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
Hao W, Meng H, Li H, Zheng Y, Song C, Jiang Z, Bai X, Zhang Z, Du L, Liu P, Wu H
Nutrients 2022 Oct 5;14(19)
Nutrients 2022 Oct 5;14(19)
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
Ramani K, Mavila N, Abeynayake A, Tomasi ML, Wang J, Matsuda M, Seki E
eLife 2022 Oct 4;11
eLife 2022 Oct 4;11
IGF2BP2 Promotes Epithelial to Mesenchymal Transition and Metastasis through Stabilizing HMGA1 mRNA in Gastric Cancer.
Ouyang J, Li J, Li D, Jiang J, Hao T, Xia Y, Lu X, Zhang C, He Y
Cancers 2022 Oct 31;14(21)
Cancers 2022 Oct 31;14(21)
Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss.
Hou W, Chen M, Ye C, Chen E, Li W, Zhang W
Biomolecules 2022 Oct 31;12(11)
Biomolecules 2022 Oct 31;12(11)
CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment.
Pan Z, Xu T, Bao L, Hu X, Jin T, Chen J, Chen J, Qian Y, Lu X, Li L, Zheng G, Zhang Y, Zou X, Song F, Zheng C, Jiang L, Wang J, Tan Z, Huang P, Ge M
Molecular cancer 2022 Oct 3;21(1):190
Molecular cancer 2022 Oct 3;21(1):190
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Liu Z, Liu R, Wang R, Dai J, Chen H, Wang J, Li X
Food & function 2022 Oct 3;13(19):9973-9987
Food & function 2022 Oct 3;13(19):9973-9987
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
He H, Liu M, He R, Zhao W
Food & function 2022 Oct 3;13(19):10265-10274
Food & function 2022 Oct 3;13(19):10265-10274
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
Zhou C, Li S, Bin K, Qin G, Pan P, Ren D, Zhao Y, Xia W, Chen J, Liu J, Wu H, Zhou Y
Cancer letters 2022 Oct 28;547:215855
Cancer letters 2022 Oct 28;547:215855
Integrated multi-omics approach revealed cellular senescence landscape.
Song Q, Hou Y, Zhang Y, Liu J, Wang Y, Fu J, Zhang C, Cao M, Cui Y, Zhang X, Wang X, Zhang J, Liu C, Zhang Y, Wang P
Nucleic acids research 2022 Oct 28;50(19):10947-10963
Nucleic acids research 2022 Oct 28;50(19):10947-10963
A network pharmacology-based study on the mechanism of astragaloside IV alleviating renal fibrosis through the AKT1/GSK-3β pathway.
Yu X, Xiao Q, Yu X, Cheng Y, Lin H, Xiang Z
Journal of ethnopharmacology 2022 Oct 28;297:115535
Journal of ethnopharmacology 2022 Oct 28;297:115535
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Ba T, Zhao D, Chen Y, Zeng C, Zhang C, Niu S, Dai H
Nutrients 2022 Oct 28;14(21)
Nutrients 2022 Oct 28;14(21)
Equus β-Defensin-1 Regulates Innate IMMUNE Response in S. aureus-Infected Mouse Monocyte Macrophage.
Pei L, Liu K, Wei W, Su H, Li F, Feng Y, Wang D, Li X, Hou Y, Cao G
Animals : an open access journal from MDPI 2022 Oct 27;12(21)
Animals : an open access journal from MDPI 2022 Oct 27;12(21)
Long-Term Protein Restriction Modulates Lipid Metabolism in White Adipose Tissues and Alters Colonic Microbiota of Shaziling Pigs.
Zheng J, Duan Y, Zheng C, Yu J, Li F, Guo Q, Yin Y
Animals : an open access journal from MDPI 2022 Oct 26;12(21)
Animals : an open access journal from MDPI 2022 Oct 26;12(21)
Berberine mitigates hepatic insulin resistance by enhancing mitochondrial architecture via the SIRT1/Opa1 signalling pathway.
Xu J, Zhang Y, Yu Z, Guan Y, Lv Y, Zhang M, Zhang M, Chen L, Lv X, Guan F
Acta biochimica et biophysica Sinica 2022 Oct 25;54(10):1464-1475
Acta biochimica et biophysica Sinica 2022 Oct 25;54(10):1464-1475
A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis.
Stomberski CT, Venetos NM, Zhou HL, Qian Z, Collison BR, Field SJ, Premont RT, Stamler JS
Cell reports 2022 Oct 25;41(4):111538
Cell reports 2022 Oct 25;41(4):111538
Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1.
Xie X, Hu L, Mi B, Xue H, Hu Y, Panayi AC, Endo Y, Chen L, Yan C, Lin Z, Li H, Zhou W, Liu G
Cell communication and signaling : CCS 2022 Oct 25;20(1):165
Cell communication and signaling : CCS 2022 Oct 25;20(1):165
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
Sun M, Zhang X, Bi F, Wang D, Zhou X, Li X, Yang Q
Cancers 2022 Oct 25;14(21)
Cancers 2022 Oct 25;14(21)
DDX17 promotes the growth and metastasis of lung adenocarcinoma.
Liu X, Li L, Geng C, Wen S, Zhang C, Deng C, Gao X, Zhang G, He QY, Liu L
Cell death discovery 2022 Oct 22;8(1):425
Cell death discovery 2022 Oct 22;8(1):425
Analysis of RIOK2 Functions in Mediating the Toxic Effects of Deoxynivalenol in Porcine Intestinal Epithelial Cells.
Gao Z, Xu C, Fan H, Wang H, Wu Z, Wu S, Bao W
International journal of molecular sciences 2022 Oct 22;23(21)
International journal of molecular sciences 2022 Oct 22;23(21)
Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity.
Li Y, Huang J, Zhu J, Bao L, Wang H, Jiang Y, Tian K, Wang R, Zheng H, Duan W, Lai W, Yi X, Zhu Y, Guo T, Ji X
Molecular cell 2022 Oct 20;82(20):3943-3959.e11
Molecular cell 2022 Oct 20;82(20):3943-3959.e11
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Zhang X, Tian L, Li Z, Liu R, Yu J, Liu B
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Lack of NPR1 Increases Vascular Endothelial Adhesion through Induction of Integrin Beta 4.
Liu H, Liu J, Long C, Chen L, Zhan W, Xiao W, Gong X, Liu M, Tian XL, Chen S
International journal of molecular sciences 2022 Oct 20;23(20)
International journal of molecular sciences 2022 Oct 20;23(20)
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
Zhou GP, Li SP, Jiang YZ, Sun J, Tan YL, Zeng ZG, Wei L, Qu W, Sun LY, Zhu ZJ
Journal of translational medicine 2022 Oct 20;20(1):479
Journal of translational medicine 2022 Oct 20;20(1):479
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Zhan Y, Zhang Z, Liu Y, Fang Y, Xie Y, Zheng Y, Li G, Liang L, Ding Y
BMC medicine 2022 Oct 19;20(1):365
BMC medicine 2022 Oct 19;20(1):365
Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice.
Yin H, Feng Y, Duan Y, Ma S, Guo Z, Wei Y
Journal of inflammation (London, England) 2022 Oct 17;19(1):16
Journal of inflammation (London, England) 2022 Oct 17;19(1):16
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Zou L, Bao W, Gao Y, Chen M, Wu Y, Wang S, Li C, Zhang J, Zhang D, Wang Q, Zhu A
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
Zhu X, Peng J, Yang L, Guo Y, Wang P, Liu K, Zhu J, Deng S, Liang M
European journal of pharmacology 2022 Oct 15;933:175268
European journal of pharmacology 2022 Oct 15;933:175268
Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis.
Wang L, Zhang Y, Ren Y, Yang X, Ben H, Zhao F, Yang S, Wang L, Qing J
European journal of pharmacology 2022 Oct 15;932:175241
European journal of pharmacology 2022 Oct 15;932:175241
MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats.
Zhang F, Gou Z, Zhou Y, Huang L, Shao C, Wang M, Wu C, Lu L
Brain research bulletin 2022 Oct 15;189:139-150
Brain research bulletin 2022 Oct 15;189:139-150
KLK12 Regulates MMP-1 and MMP-9 via Bradykinin Receptors: Biomarkers for Differentiating Latent and Active Bovine Tuberculosis.
Wang Y, Qu M, Liu Y, Wang H, Dong Y, Zhou X
International journal of molecular sciences 2022 Oct 14;23(20)
International journal of molecular sciences 2022 Oct 14;23(20)
Transcriptional Responses of Copper-Transport-Related Genes ctr1, ctr2 and atox1 and Their Roles in the Regulation of Cu Homeostasis in Yellow Catfish Pelteobagrus fulvidraco.
Yang H, Zhong C, Tan X, Chen G, He Y, Liu S, Luo Z
International journal of molecular sciences 2022 Oct 13;23(20)
International journal of molecular sciences 2022 Oct 13;23(20)
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H(2)O(2)-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Xiong L, Wu H, Zhong T, Luo F, Li Q, Li M, Fan Y
Antioxidants (Basel, Switzerland) 2022 Oct 12;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 12;11(10)
The Mixture of Ferulic Acid and P-Coumaric Acid Suppresses Colorectal Cancer through lncRNA 495810/PKM2 Mediated Aerobic Glycolysis.
Cui K, Wu H, Fan J, Zhang L, Li H, Guo H, Yang R, Li Z
International journal of molecular sciences 2022 Oct 11;23(20)
International journal of molecular sciences 2022 Oct 11;23(20)
MicroRNA-223 negatively regulates the osteogenic differentiation of periodontal ligament derived cells by directly targeting growth factor receptors.
Zhang Z, Wang M, Zheng Y, Dai Y, Chou J, Bian X, Wang P, Li C, Shen J
Journal of translational medicine 2022 Oct 11;20(1):465
Journal of translational medicine 2022 Oct 11;20(1):465
Accelerated Bone Regeneration by an Astaxanthin-Modified Antioxidant Aerogel through Relieving Oxidative Stress via the NRF2 Signaling Pathway.
Guo J, Yang X, Chen J, Wang C, Kang Y, Jiang T, Chen M, Li W, Zhou C, Chen Z
ACS biomaterials science & engineering 2022 Oct 10;8(10):4524-4534
ACS biomaterials science & engineering 2022 Oct 10;8(10):4524-4534
Stain-Free total-protein normalization enhances the reproducibility of Western blot data.
Maloy A, Alexander S, Andreas A, Nyunoya T, Chandra D
Analytical biochemistry 2022 Oct 1;654:114840
Analytical biochemistry 2022 Oct 1;654:114840
NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.
Cai Y, Zhu Y, Zheng J, Zhang Y, Chen W
Biochemical and biophysical research communications 2022 Oct 1;623:140-147
Biochemical and biophysical research communications 2022 Oct 1;623:140-147
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Li X, Liu D, Chen H, Zeng B, Zhao Q, Zhang Y, Chen Y, Wang J, Xing HR
Biological research 2022 Oct 1;55(1):29
Biological research 2022 Oct 1;55(1):29
Neutrophil extracellular traps accelerate vascular smooth muscle cell proliferation via Akt/CDKN1b/TK1 accompanying with the occurrence of hypertension.
Fang X, Ma L, Wang Y, Ren F, Yu Y, Yuan Z, Wei H, Zhang H, Sun Y
Journal of hypertension 2022 Oct 1;40(10):2045-2057
Journal of hypertension 2022 Oct 1;40(10):2045-2057
Pharmacological inhibition of the cGAS-STING signaling pathway suppresses microglial M1-polarization in the spinal cord and attenuates neuropathic pain.
Wu W, Zhang X, Wang S, Li T, Hao Q, Li S, Yao W, Sun R
Neuropharmacology 2022 Oct 1;217:109206
Neuropharmacology 2022 Oct 1;217:109206
CPNE1 silencing inhibits cell proliferation and accelerates apoptosis in human gastric cancer.
Li Y, Li L, Liu H, Zhou T
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2022 Oct 1;177:106278
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2022 Oct 1;177:106278
MORC3 restricts human cytomegalovirus infection by suppressing the major immediate-early promoter activity.
Ma XH, Yao YX, Wang XZ, Zhou YP, Huang SN, Li D, Mei MJ, Wu JP, Pan YT, Cheng S, Jiang X, Sun JY, Zeng WB, Gong S, Cheng H, Luo MH, Yang B
Journal of medical virology 2022 Nov;94(11):5492-5506
Journal of medical virology 2022 Nov;94(11):5492-5506
The mitochondrial enzyme FAHD1 regulates complex II activity in breast cancer cells and is indispensable for basal BT-20 cells in vitro.
Holzknecht M, Guerrero-Navarro L, Petit M, Albertini E, Damisch E, Simonini A, Schmitt F, Parson W, Fiegl H, Weiss A, Jansen-Duerr P
FEBS letters 2022 Nov;596(21):2781-2794
FEBS letters 2022 Nov;596(21):2781-2794
Pathogenic effects of Desulfovibrio in the gut on fatty liver in diet-induced obese mice and children with obesity.
Lin YC, Lin HF, Wu CC, Chen CL, Ni YH
Journal of gastroenterology 2022 Nov;57(11):913-925
Journal of gastroenterology 2022 Nov;57(11):913-925
Long noncoding RNA SNHG8 promotes chemoresistance in gastric cancer via binding with hnRNPA1 and stabilizing TROY expression.
Zhu W, Tan L, Ma T, Yin Z, Gao J
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Nov;54(11):1573-1582
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Nov;54(11):1573-1582
[Effects of Long-Term Ethanol Consumption on Learning-Memory Functions in Mice and the Mechanisms Involved].
Zhou J, Wu W, Ji LW, Li Q, Liang Y, Li T, Yang L
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2022 Nov;53(6):1049-1054
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2022 Nov;53(6):1049-1054
Expression analysis and functional characterization of thioredoxin domain-containing protein 11.
Murase R, Yamamoto A, Hirata Y, Oh-Hashi K
Molecular biology reports 2022 Nov;49(11):10541-10556
Molecular biology reports 2022 Nov;49(11):10541-10556
RNA-Seq approach to investigate the effects of melatonin on bone marrow-derived dendritic cells from dextran sodium sulfate-induced colitis mice.
Feng S, Xu Z, Zhang Z, Mo Y, Deng Y, Li L, Fei S, Wu J, Wang K, Zhang Q, Song J, Zhou R
Toxicology 2022 Nov;481:153354
Toxicology 2022 Nov;481:153354
Impaired autophagy and mitochondrial dynamics are involved in Sorafenib-induced cardiomyocyte apoptosis.
Liang F, Zhang K, Ma W, Zhan H, Sun Q, Xie L, Zhao Z
Toxicology 2022 Nov;481:153348
Toxicology 2022 Nov;481:153348
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Wang T, Liu J, Huang X, Zhang C, Shangguan M, Chen J, Wu S, Chen M, Yang Z, Zhao S
Oncology reports 2022 Nov;48(5)
Oncology reports 2022 Nov;48(5)
Estrogen receptor variant ER-α36 facilitates estrogen signaling via EGFR in glioblastoma.
Qu C, Wang C, Li H, Li Y, Han C, Tao X, Guan X, Zhang Y, Chen M, Liu J, Zou W
Cell biology international 2022 Nov;46(11):1759-1774
Cell biology international 2022 Nov;46(11):1759-1774
Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis.
Zheng XJ, Chen WL, Yi J, Li W, Liu JY, Fu WQ, Ren LW, Li S, Ge BB, Yang YH, Zhang YZ, Yang H, Du GH, Wang Y, Wang JH
Acta pharmacologica Sinica 2022 Nov;43(11):2977-2992
Acta pharmacologica Sinica 2022 Nov;43(11):2977-2992
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Wang C, Long Q, Fu Q, Xu Q, Fu D, Li Y, Gao L, Guo J, Zhang X, Lam EW, Campisi J, Sun Y
Oncogene 2022 Nov;41(45):4941-4959
Oncogene 2022 Nov;41(45):4941-4959
Roles of C/EBP-homologous protein and histone H3 lysine 4 methylation in arsenic-induced mitochondrial apoptosis in hepatocytes.
Liang C, Xie RJ, Wang JL, Zhang YW, Zhang JY, Yang Q, Han B
Toxicology and industrial health 2022 Nov;38(11):745-756
Toxicology and industrial health 2022 Nov;38(11):745-756
Cadmium exposure induces autophagy via PLC-IP(3) -IP(3) R signaling pathway in duck renal tubular epithelial cells.
Guo H, Huang B, Cui T, Chu X, Pu W, Huang G, Xing C, Zhang C
Environmental toxicology 2022 Nov;37(11):2660-2672
Environmental toxicology 2022 Nov;37(11):2660-2672
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Shen J, Wu X, Zhu P, Zhuang J, Qin B, Sun F, Yuan W, Fan X, Jiang Z, Li F, Li Y, Wang Y, Zhao M
Human cell 2022 Nov;35(6):1722-1735
Human cell 2022 Nov;35(6):1722-1735
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment.
Xu A, Yang R, Zhang M, Wang X, Di Y, Jiang B, Di Y, Zhou Z, Zhou L
Journal of drug targeting 2022 Nov;30(9):961-972
Journal of drug targeting 2022 Nov;30(9):961-972
Metabolomic Analysis Reveals that SPHK1 Promotes Oral Squamous Cell Carcinoma Progression through NF-κB Activation.
Hou CX, Mao GY, Sun QW, Meng Y, Zhu QH, Tang YT, Han W, Sun NN, Song XM, Wang CX, Ye JH
Annals of surgical oncology 2022 Nov;29(12):7386-7399
Annals of surgical oncology 2022 Nov;29(12):7386-7399
Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFβ/SMADs signaling pathway.
Jin Z, Tian L, Zhang Y, Zhang X, Kang J, Dong H, Huang N, Pan L, Ning B
CNS neuroscience & therapeutics 2022 Nov;28(11):1883-1894
CNS neuroscience & therapeutics 2022 Nov;28(11):1883-1894
SIRT3 expression alleviates microglia activation‑induced dopaminergic neuron injury through the mitochondrial pathway.
Jiang DQ, Zang QM, Jiang LL, Lu CS, Zhao SH, Xu LC
Experimental and therapeutic medicine 2022 Nov;24(5):662
Experimental and therapeutic medicine 2022 Nov;24(5):662
Human gingival mesenchymal stem cells improve movement disorders and tyrosine hydroxylase neuronal damage in Parkinson disease rats.
Lei T, Xiao Z, Zhang X, Cai S, Bi W, Yang Y, Wang D, Li Q, Du H
Cytotherapy 2022 Nov;24(11):1105-1120
Cytotherapy 2022 Nov;24(11):1105-1120
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Lin S, Li Q, Xu Z, Chen Z, Tao Y, Tong Y, Wang T, Chen S, Wang P
Psychopharmacology 2022 Nov;239(11):3657-3677
Psychopharmacology 2022 Nov;239(11):3657-3677
Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease.
Ruf WP, Palmer A, Dörfer L, Wiesner D, Buck E, Grozdanov V, Kassubek J, Dimou L, Ludolph AC, Huber-Lang M, Danzer KM
Neurobiology of disease 2022 Nov;174:105877
Neurobiology of disease 2022 Nov;174:105877
Galactosylceramidase deficiency and pathological abnormalities in cerebral white matter of Krabbe disease.
Iacono D, Koga S, Peng H, Manavalan A, Daiker J, Castanedes-Casey M, Martin NB, Herdt AR, Gelb MH, Dickson DW, Lee CW
Neurobiology of disease 2022 Nov;174:105862
Neurobiology of disease 2022 Nov;174:105862
Maizediterpene D from the roots of Zea mays L. alleviates hydrogen peroxide induced oxidative stress and improves cell survival by activation of TrkB/IGF-1R crosstalk pathways.
Fan Y, Wu H, Xiong L, Luo F, Li Q, Wang D, Zhong T
Fitoterapia 2022 Nov;163:105314
Fitoterapia 2022 Nov;163:105314
Elevated Notch-1 expression promotes the lymph node metastasis of gastric cancer and the Notch-1-PTEN-ERK1/2 signalling axis promotes the progression of gastric cancer.
Ma H, Li N, Mo Z
Cytokine 2022 Nov;159:156013
Cytokine 2022 Nov;159:156013
1-Deoxynojirimycin attenuates septic cardiomyopathy by regulating oxidative stress, apoptosis, and inflammation via the JAK2/STAT6 signaling pathway.
Jiang L, Zhang L, Yang J, Shi H, Zhu H, Zhai M, Lu L, Wang X, Li XY, Yu S, Liu J, Duan W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113648
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113648
Postnatal state transition of cardiomyocyte as a primary step in heart maturation.
Li Z, Yao F, Yu P, Li D, Zhang M, Mao L, Shen X, Ren Z, Wang L, Zhou B
Protein & cell 2022 Nov;13(11):842-862
Protein & cell 2022 Nov;13(11):842-862
Astragalin mitigates inflammatory osteolysis by negatively modulating osteoclastogenesis via ROS and MAPK signaling pathway.
Xing F, Geng L, Guan H, Liu D, Li Y, Zeng L, Chen Y, Tian R, Li Z, Cao R, Zhao Y, Yan P, Qiang H, Kong N, Wang K, Yang P
International immunopharmacology 2022 Nov;112:109278
International immunopharmacology 2022 Nov;112:109278
Grossamide attenuates inflammation by balancing macrophage polarization through metabolic reprogramming of macrophages in mice.
Zhao W, Xu D, Hong W, Zhang L, Wu Q, Gao M, Wang J
International immunopharmacology 2022 Nov;112:109190
International immunopharmacology 2022 Nov;112:109190
Long non-coding RNA DLGAP1-AS1 modulates the development of non-small-cell lung cancer via the microRNA-193a-5p/DTL axis.
Pan X, Chen S, Ye L, Xu S, Wang L, Sun Y
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1182-1191
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1182-1191
Effect of crosstalk between Th17 and Th9 cells on the activation of dermal vascular smooth muscle cells in systemic scleroderma and regulation of tanshinone IIA.
Liu M
Anais brasileiros de dermatologia 2022 Nov-Dec;97(6):716-728
Anais brasileiros de dermatologia 2022 Nov-Dec;97(6):716-728
Meiotic nuclear divisions 1 promotes proliferation and metastasis in hepatocellular carcinoma and is a potential diagnostic and therapeutic target gene.
Tan K, Wang K, Zhao A, Liu Z, Song W, Cheng Q, Li X, Chen Z, Yuan Y, Yang Z
Medical oncology (Northwood, London, England) 2022 Nov 9;40(1):14
Medical oncology (Northwood, London, England) 2022 Nov 9;40(1):14
Pirfenidone-loaded exosomes derived from pancreatic ductal adenocarcinoma cells alleviate fibrosis of premetastatic niches to inhibit liver metastasis.
Zhao J, Zhu Y, Li Z, Liang J, Zhang Y, Zhou S, Zhang Y, Fan Z, Shen Y, Liu Y, Zhang F, Shen S, Xu G, Wang L, Lv Y, Zhang S, Zou X
Biomaterials science 2022 Nov 8;10(22):6614-6626
Biomaterials science 2022 Nov 8;10(22):6614-6626
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Qin C, Li T, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cancer cell international 2022 Nov 7;22(1):340
Cancer cell international 2022 Nov 7;22(1):340
SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.
Tian Y, Liu R, Hou X, Gao Z, Liu X, Zhang W
Cell death & disease 2022 Nov 7;13(11):935
Cell death & disease 2022 Nov 7;13(11):935
The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia.
Bai X, Qi Z, Zhu M, Lu Z, Zhao X, Zhang L, Song G
Stem cell research & therapy 2022 Nov 4;13(1):512
Stem cell research & therapy 2022 Nov 4;13(1):512
FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway.
Sun Y, Ying X, Li R, Weng M, Shi J, Chen Z
Biomolecules 2022 Nov 4;12(11)
Biomolecules 2022 Nov 4;12(11)
Vaccination with a shared oncogenic tumor-self antigen elicits a population of CD8+ T cells with a regulatory phenotype.
Elizondo CR, Bright JD, Bright RK
Human vaccines & immunotherapeutics 2022 Nov 30;18(6):2108656
Human vaccines & immunotherapeutics 2022 Nov 30;18(6):2108656
Dipsacoside B Inhibits the Migration and Proliferation of VSMCs and Blunts Neointimal Formation by Upregulating PTEN Expression.
Quan W, Huo Y, Chen Y, Yang D, Xie J, Shi Z, Liao D, Tuo Q
Frontiers in bioscience (Landmark edition) 2022 Nov 3;27(11):299
Frontiers in bioscience (Landmark edition) 2022 Nov 3;27(11):299
Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation.
Chen C, Zhang W, Zhou T, Liu Q, Han C, Huang Z, Chen S, Mei Q, Zhang C, Zhang K, Ma H, Zhou R, Jiang W, Pan W, Zhu S
Cell reports 2022 Nov 29;41(9):111741
Cell reports 2022 Nov 29;41(9):111741
Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study.
Chang GH, Yang PR, Cheng YC, Hsu KH, Wu CY, Yang YH, Lin YS, Hsu CM, Tsai MS, Tsai YT, Chang PJ
BMC complementary medicine and therapies 2022 Nov 29;22(1):313
BMC complementary medicine and therapies 2022 Nov 29;22(1):313
An RNAi screen of RNA helicases identifies eIF4A3 as a regulator of embryonic stem cell identity.
Li D, Yang J, Malik V, Huang Y, Huang X, Zhou H, Wang J
Nucleic acids research 2022 Nov 28;50(21):12462-12479
Nucleic acids research 2022 Nov 28;50(21):12462-12479
Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway.
Lin L, Gao Y, Hu X, Ouyang J, Liu C
BMC women's health 2022 Nov 24;22(1):470
BMC women's health 2022 Nov 24;22(1):470
Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats.
Wang C, Li Y, Yi Y, Liu G, Guo R, Wang L, Lan T, Wang W, Chen X, Chen S, Yu SY
Journal of neuroinflammation 2022 Nov 24;19(1):283
Journal of neuroinflammation 2022 Nov 24;19(1):283
Bombesin receptor-activated protein exacerbates cisplatin-induced AKI by regulating the degradation of SIRT2.
Peng L, Liu D, Liu H, Xia M, Wan L, Li M, Zhao J, Tang C, Chen G, Qu X, Dong Z, Liu H
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2022 Nov 23;37(12):2366-2385
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2022 Nov 23;37(12):2366-2385
VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway.
Zhang X, Zhou K, Tian K, Zhu Q, Liu W, Liu Z, An X, Tian C, Li Y, Lu F, Sun F, Zha D
Cells 2022 Nov 23;11(23)
Cells 2022 Nov 23;11(23)
Antitumor Activity and Mechanism of Action of the Antimicrobial Peptide AMP-17 on Human Leukemia K562 Cells.
Tian Z, Yang L, Huang M, Sun C, Chen M, Zhao W, Peng J, Guo G
Molecules (Basel, Switzerland) 2022 Nov 21;27(22)
Molecules (Basel, Switzerland) 2022 Nov 21;27(22)
The Crosstalk between HepG2 and HMC-III Cells: In Vitro Modulation of Gene Expression with Conditioned Media.
Koshal P, Matera I, Abruzzese V, Ostuni A, Bisaccia F
International journal of molecular sciences 2022 Nov 21;23(22)
International journal of molecular sciences 2022 Nov 21;23(22)
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Han P, Wang X, Zhou T, Cheng J, Wang C, Sun F, Zhao X
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Follicle-Stimulating Hormone Promotes the Development of Endometrial Cancer In Vitro and In Vivo.
Sheng S, Liu W, Xue Y, Pan Z, Zhao L, Wang F, Qi X
International journal of environmental research and public health 2022 Nov 20;19(22)
International journal of environmental research and public health 2022 Nov 20;19(22)
Trpc5-regulated AMPKα/mTOR autophagy pathway is associated with glucose metabolism disorders in low birth weight mice under overnutrition.
Zhou F, Yang L, Yang L, Wang X, Guo N, Sun W, Ma H
Biochemical and biophysical research communications 2022 Nov 19;630:1-7
Biochemical and biophysical research communications 2022 Nov 19;630:1-7
Dual Inhibition of BRAF-MAPK and STAT3 Signaling Pathways in Resveratrol-Suppressed Anaplastic Thyroid Cancer Cells with BRAF Mutations.
Lu MD, Li H, Nie JH, Li S, Ye HS, Li TT, Wu ML, Liu J
International journal of molecular sciences 2022 Nov 19;23(22)
International journal of molecular sciences 2022 Nov 19;23(22)
Self-assembly of DNA nanostructure containing cell-specific aptamer as a precise drug delivery system for cancer therapy in non-small cell lung cancer.
Wang N, Yu C, Xu T, Yao D, Zhu L, Shen Z, Huang X
Journal of nanobiotechnology 2022 Nov 19;20(1):486
Journal of nanobiotechnology 2022 Nov 19;20(1):486
TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals.
Liudkovska V, Krawczyk PS, Brouze A, Gumińska N, Wegierski T, Cysewski D, Mackiewicz Z, Ewbank JJ, Drabikowski K, Mroczek S, Dziembowski A
Science advances 2022 Nov 18;8(46):eadd9468
Science advances 2022 Nov 18;8(46):eadd9468
JMJD1C Regulates Megakaryopoiesis in In Vitro Models through the Actin Network.
Wang J, Liu X, Wang H, Qin L, Feng A, Qi D, Wang H, Zhao Y, Kong L, Wang H, Wang L, Hu Z, Xu X
Cells 2022 Nov 18;11(22)
Cells 2022 Nov 18;11(22)
Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci.
Stein CB, Field AR, Mimoso CA, Zhao C, Huang KL, Wagner EJ, Adelman K
Molecular cell 2022 Nov 17;82(22):4232-4245.e11
Molecular cell 2022 Nov 17;82(22):4232-4245.e11
SOX4 Mediates ATRA-Induced Differentiation in Neuroblastoma Cells.
Zhang D, Gong B, Zhao Q, Li Z, Tan X, Hua Z
Cancers 2022 Nov 17;14(22)
Cancers 2022 Nov 17;14(22)
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Liu Y, Azizian NG, Sullivan DK, Li Y
Nature communications 2022 Nov 17;13(1):7047
Nature communications 2022 Nov 17;13(1):7047
WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC.
Wang R, Zhao J, Jin J, Tian Y, Lan L, Wang X, Zhu L, Wang J
Lipids in health and disease 2022 Nov 16;21(1):121
Lipids in health and disease 2022 Nov 16;21(1):121
"All-in-One" Exosome Engineering Strategy for Effective Therapy of Familial Hypercholesterolemia.
Mei R, Wan Z, Li Z, Wei M, Qin W, Yuan L, Liu L, Yang G
ACS applied materials & interfaces 2022 Nov 16;14(45):50626-50636
ACS applied materials & interfaces 2022 Nov 16;14(45):50626-50636
The long noncoding RNA TINCR promotes self-renewal of human liver cancer stem cells through autophagy activation.
Shi J, Guo C, Li Y, Ma J
Cell death & disease 2022 Nov 16;13(11):961
Cell death & disease 2022 Nov 16;13(11):961
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
Wang J, Wen J, Ma X, Yang J, Zhang Z, Xie S, Wei S, Jing M, Li H, Lang L, Zhou X, Zhao Y
European journal of pharmacology 2022 Nov 15;935:175331
European journal of pharmacology 2022 Nov 15;935:175331
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Hu S, Hu C, Luo L, Zhang H, Zhao S, Liu Z, Zeng L
Food chemistry 2022 Nov 15;394:133500
Food chemistry 2022 Nov 15;394:133500
Jatrorrhizine from Rhizoma Coptidis exerts an anti-obesity effect in db/db mice.
He H, Deng J, Yang M, An L, Ye X, Li X
Journal of ethnopharmacology 2022 Nov 15;298:115529
Journal of ethnopharmacology 2022 Nov 15;298:115529
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Pan Z, Chen Y, Pang H, Wang X, Zhang Y, Xie X, He G
European journal of medicinal chemistry 2022 Nov 15;242:114674
European journal of medicinal chemistry 2022 Nov 15;242:114674
Luteolin can ameliorate renal interstitial fibrosis-induced renal anaemia through the SIRT1/FOXO3 pathway.
Li F, Wei R, Huang M, Chen J, Li P, Ma Y, Chen X
Food & function 2022 Nov 14;13(22):11896-11914
Food & function 2022 Nov 14;13(22):11896-11914
Lactate Activates AMPK Remodeling of the Cellular Metabolic Profile and Promotes the Proliferation and Differentiation of C2C12 Myoblasts.
Zhou Y, Liu X, Huang C, Lin D
International journal of molecular sciences 2022 Nov 13;23(22)
International journal of molecular sciences 2022 Nov 13;23(22)
Stress-induced reduction of Na(+)/H(+) exchanger isoform 1 promotes maladaptation of neuroplasticity and exacerbates depressive behaviors.
Li Y, Fan C, Wang C, Wang L, Yi Y, Mao X, Chen X, Lan T, Wang W, Yu SY
Science advances 2022 Nov 11;8(45):eadd7063
Science advances 2022 Nov 11;8(45):eadd7063
Brca1 Is Regulated by the Transcription Factor Gata3, and Its Silencing Promotes Neural Differentiation in Retinal Neurons.
Zhuang J, Chen P, Wu Y, Luo Q, Wang Q, Chen S, Chen X, Jiang Z, Qiu J, Li Y, Yuan Z, Zhuang J
International journal of molecular sciences 2022 Nov 10;23(22)
International journal of molecular sciences 2022 Nov 10;23(22)
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway.
Yu J, Wang K, Yang S, Li G
Toxicology and applied pharmacology 2022 Nov 1;454:116232
Toxicology and applied pharmacology 2022 Nov 1;454:116232
G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway.
Yuan Z, Ren R, Xu Z
Anti-cancer drugs 2022 Nov 1;33(10):1004-1011
Anti-cancer drugs 2022 Nov 1;33(10):1004-1011
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
Molecular and functional characterization of teleost-specific Interleukin-17N in yellow catfish (Pelteobagrus fulvidraco).
Zhou X, Jiang XX, Zhang GR, Ji W, Shi ZC, Ma XF, Wei KJ
International journal of biological macromolecules 2022 Nov 1;220:493-509
International journal of biological macromolecules 2022 Nov 1;220:493-509
MiR-18 inhibitor promotes the differentiation of bovine skeletal muscle-derived satellite cells by increasing MEF2D expression.
Meng B, Jiang D, Kong D, Yan Y, Nie Y, Teng CB, Liang Y
Journal of animal science 2022 Nov 1;100(11)
Journal of animal science 2022 Nov 1;100(11)
Salidroside inhibits doxorubicin-induced cardiomyopathy by modulating a ferroptosis-dependent pathway.
Chen H, Zhu J, Le Y, Pan J, Liu Y, Liu Z, Wang C, Dou X, Lu D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153964
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153964
Trillin inhibits myoblast differentiation via increasing autophagy.
Dai W, Liu K, Li R, Cao Y, Shen M, Tao J, Liu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153962
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153962
Mechanical force-sensitive lncRNA SNHG8 inhibits osteogenic differentiation by regulating EZH2 in hPDLSCs.
Zhang Z, He Q, Yang S, Zhao X, Li X, Wei F
Cellular signalling 2022 May;93:110285
Cellular signalling 2022 May;93:110285
TREM2 ameliorates anesthesia and surgery-induced cognitive impairment by regulating mitophagy and NLRP3 inflammasome in aged C57/BL6 mice.
Jiang W, Liu F, Li H, Wang K, Cao X, Xu X, Zhou Y, Zou J, Zhang X, Cui X
Neurotoxicology 2022 May;90:216-227
Neurotoxicology 2022 May;90:216-227
Role of thioredoxin-interacting protein in mediating endothelial dysfunction in hypertension.
Wang R, Guo Y, Li L, Luo M, Peng L, Lv D, Cheng Z, Xue Q, Wang L, Huang J
Genes & diseases 2022 May;9(3):753-765
Genes & diseases 2022 May;9(3):753-765
Cadmium exposure suppresses insulin secretion through mtROS-mediated mitochondrial dysfunction and inflammatory response in pancreatic beta cells.
Hong H, He H, Lin X, Hayuehashi T, Xu J, Zhang J, Xu Y, Tong T, Lu Y, Zhou Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2022 May;71:126952
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2022 May;71:126952
Exosomes derived from olfactory ensheathing cells provided neuroprotection for spinal cord injury by switching the phenotype of macrophages/microglia.
Fan H, Chen Z, Tang HB, Shan LQ, Chen ZY, Wang XH, Huang DG, Liu SC, Chen X, Yang H, Hao D
Bioengineering & translational medicine 2022 May;7(2):e10287
Bioengineering & translational medicine 2022 May;7(2):e10287
Effects of BMAL1 on dentinogenic differentiation of dental pulp stem cells via PI3K/Akt/mTOR pathway.
Xu H, Zhao J, Chen G, Yuan Z, Liu J
International endodontic journal 2022 May;55(5):505-516
International endodontic journal 2022 May;55(5):505-516
Heterozygote loss-of-function variants in the LRP5 gene cause familial exudative vitreoretinopathy.
Zhao R, Wang S, Zhao P, Dai E, Zhang X, Peng L, He Y, Yang M, Li S, Yang Z
Clinical & experimental ophthalmology 2022 May;50(4):441-448
Clinical & experimental ophthalmology 2022 May;50(4):441-448
CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling.
Chen D, Zhang Y, Ji L, Wu Y
Cell biology international 2022 May;46(5):849-860
Cell biology international 2022 May;46(5):849-860
Neuregulin-1 promotes the proliferation, migration, and angiogenesis of human periodontal ligament stem cells in vitro.
Li L, Shang L, Kang W, Du L, Ge S
Cell biology international 2022 May;46(5):792-805
Cell biology international 2022 May;46(5):792-805
Guanylate-binding Protein 2 Expression Is Associated With Poor Survival and Malignancy in Clear-cell Renal Cell Carcinoma.
Liu Q, Hoffman RM, Song J, Miao S, Zhang J, Ding D, Wang D
Anticancer research 2022 May;42(5):2341-2354
Anticancer research 2022 May;42(5):2341-2354
Activated Phosphoinositide 3-Kinase δ Syndrome: a Large Pediatric Cohort from a Single Center in China.
Qiu L, Wang Y, Tang W, Yang Q, Zeng T, Chen J, Chen X, Zhang L, Zhou L, Zhang Z, An Y, Tang X, Zhao X
Journal of clinical immunology 2022 May;42(4):837-850
Journal of clinical immunology 2022 May;42(4):837-850
Polyvinylamine with moderate binding affinity as a highly effective vehicle for RNA delivery.
Tian Y, Zhao Y, Yin C, Tan S, Wang X, Yang C, Zhang TD, Zhang X, Ye F, Xu J, Wu X, Ding L, Zhang J, Pei J, Wang XT, Zhang RX, Xu J, Wang W, Filipe CDM, Hoare T, Yin DC, Qian A, Deng X
Journal of controlled release : official journal of the Controlled Release Society 2022 May;345:20-37
Journal of controlled release : official journal of the Controlled Release Society 2022 May;345:20-37
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy.
Liu F, Dai Z, Cheng Q, Xu L, Huang L, Liu Z, Li X, Wang N, Wang G, Wang L, Wang Z
Biomaterials 2022 May;284:121485
Biomaterials 2022 May;284:121485
Combination of ruthenium (II) polypyridyl complex Δ-Ru1 and Taxol enhances the anti-cancer effect on Taxol-resistant cancer cells through Caspase-1/GSDMD-mediated pyroptosis.
Chen D, Guo S, Tang X, Rong Y, Bo H, Shen H, Zhao Z, Qiao A, Shen J, Wang J
Journal of inorganic biochemistry 2022 May;230:111749
Journal of inorganic biochemistry 2022 May;230:111749
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
Yang L, Liu S, Yang L, Xu B, Wang M, Kong X, Song Z
Oncology letters 2022 May;23(5):162
Oncology letters 2022 May;23(5):162
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Gong J, Shen Y, Jiang F, Wang Y, Chu L, Sun J, Shen P, Chen M
Oncology letters 2022 May;23(5):148
Oncology letters 2022 May;23(5):148
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J
Biological trace element research 2022 May;200(5):2329-2337
Biological trace element research 2022 May;200(5):2329-2337
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Qin S, Wang R, Tang D, Qin S, Guo Y, Shi Z
Biological trace element research 2022 May;200(5):2312-2320
Biological trace element research 2022 May;200(5):2312-2320
Diminished Piezo2-Dependent Tactile Sensitivity Occurs in Aging Human Gut and Slows Gastrointestinal Transit in Mice.
Jones LA, Jin B, Martin AM, Wei L, Flinders Gastrointestinal Consortium, Ro S, Keating DJ
Gastroenterology 2022 May;162(6):1755-1757.e2
Gastroenterology 2022 May;162(6):1755-1757.e2
Naringenin promoted spinal microglia M2 polarization in rat model of cancer-induced bone pain via regulating AMPK/PGC-1α signaling axis.
Ge MM, Li DY, Wang L, Zhang LQ, Liu DQ, Tian YK, Ye DW, Liu ZH, Zhou YQ, Yang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112912
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112912
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Zhang D, Zheng N, Fu X, Shi J, Zhang J
Journal of thoracic disease 2022 May;14(5):1651-1662
Journal of thoracic disease 2022 May;14(5):1651-1662
Long non-coding RNA H19 alleviates hippocampal damage in convulsive status epilepticus rats through the nuclear factor-kappaB signaling pathway.
Xie Y, Wang M, Deng X, Chen Y
Bioengineered 2022 May;13(5):12783-12793
Bioengineered 2022 May;13(5):12783-12793
Chemokine (C-C motif) ligand 18/membrane-associated 3/forkhead box O1 axis promotes the proliferation, migration, and invasion of intrahepatic cholangiocarcinoma.
Wang C, Liang H, Li Y, Tang Z, Zhang Y
Bioengineered 2022 May;13(5):12738-12748
Bioengineered 2022 May;13(5):12738-12748
Methyltransferase like 7B is upregulated in sepsis and modulates lipopolysaccharide-induced inflammatory response and macrophage polarization.
Huang D, Yan H
Bioengineered 2022 May;13(5):11753-11766
Bioengineered 2022 May;13(5):11753-11766
Disheveled binding antagonist of β-catenin 1 interacted with β-catenin and connexin 43 in human-induced pluripotent stem cells-derived cardiomyocytes.
Hou J, Huang S, Long Y, Feng K, Shang L, Zhou Z, Yue Y, Huang X, Chen G, Wu Z
Bioengineered 2022 May;13(5):11594-11601
Bioengineered 2022 May;13(5):11594-11601
SNF5 promotes cell proliferation and immune evasion in non-small cell lung cancer.
Chen Y, Zhao M, Shen D, Yi Q, Tang L
Bioengineered 2022 May;13(5):11530-11540
Bioengineered 2022 May;13(5):11530-11540
Elevated BTG2 improves the radiosensitivity of non-small cell lung cancer (NSCLC) through apoptosis.
Zhu C, Zhang S, Xue A, Feng G, Fan S
Thoracic cancer 2022 May;13(10):1441-1448
Thoracic cancer 2022 May;13(10):1441-1448
miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway.
Xiao W, Jiang Z, Wan W, Pan W, Xu J
Annals of translational medicine 2022 May;10(10):571
Annals of translational medicine 2022 May;10(10):571
m6A and YTHDF proteins contribute to the localization of select neuronal mRNAs.
Flamand MN, Meyer KD
Nucleic acids research 2022 May 6;50(8):4464-4483
Nucleic acids research 2022 May 6;50(8):4464-4483
ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling.
Liu J, Wu Z, Liu Y, Zhan Z, Yang L, Wang C, Jiang Q, Ran H, Li P, Wang Z
Journal of nanobiotechnology 2022 May 6;20(1):213
Journal of nanobiotechnology 2022 May 6;20(1):213
The anti-tumor effect of proteasome inhibitor MG132 for human adenoid cystic carcinoma: correlate with the emerging role of Nrf2/Keap1 signaling pathway.
Xu J, Wu H, Sun J, Gong Z, Lu X, Yang E, Chen Z, Huang S, Nong X, Zhang D
Head & face medicine 2022 May 6;18(1):15
Head & face medicine 2022 May 6;18(1):15
Maelstrom promotes tumor metastasis through regulation of FGFR4 and epithelial-mesenchymal transition in epithelial ovarian cancer.
He WP, Yang GP, Yang ZX, Shen HW, You ZS, Yang GF
Journal of ovarian research 2022 May 6;15(1):55
Journal of ovarian research 2022 May 6;15(1):55
Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1.
Xu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W
Nature communications 2022 May 5;13(1):2467
Nature communications 2022 May 5;13(1):2467
Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.
Ding P, Xu Y, Li L, Lv X, Li L, Chen J, Zhou D, Wang X, Wang Q, Zhang W, Liao T, Ji QH, Lei QY, Hu W
Cell reports 2022 May 31;39(9):110851
Cell reports 2022 May 31;39(9):110851
Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.
Zhu X, Li K, Gao Y
Biochemical and biophysical research communications 2022 May 28;606:121-127
Biochemical and biophysical research communications 2022 May 28;606:121-127
GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer.
Shen Z, Li Z, Liu Y, Li Y, Feng X, Zhan Y, Lin M, Fang C, Fang Y, Deng H
Cancer letters 2022 May 28;534:215617
Cancer letters 2022 May 28;534:215617
CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells.
Yadavalli T, Sharma P, Wu D, Kapoor D, Shukla D
Viruses 2022 May 28;14(6)
Viruses 2022 May 28;14(6)
Inhibition of the P2X7/NLRP3 Inflammasome Signaling Pathway by Deacetylgedunin from Toona sinensis.
Li Q, Tang P, Zhang P, Cui L, Li Y, Li J, Kong L, Luo J
Journal of natural products 2022 May 27;85(5):1388-1397
Journal of natural products 2022 May 27;85(5):1388-1397
del Nido cardioplegia better preserves cardiac diastolic function but histidine-tryptophan-ketoglutarate is better for endothelial function.
Xue HM, Hou HT, Sun WT, Wang SF, Guo S, Yang Q, He GW
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2022 May 27;61(6):1368-1378
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2022 May 27;61(6):1368-1378
Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.
Yang G, Lu S, Jiang J, Weng J, Zeng X
International journal of molecular sciences 2022 May 27;23(11)
International journal of molecular sciences 2022 May 27;23(11)
GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome.
Qin Z, Song J, Lin A, Yang W, Zhang W, Zhong F, Huang L, Lü Y, Yu W
Journal of neuroinflammation 2022 May 27;19(1):121
Journal of neuroinflammation 2022 May 27;19(1):121
Alanyl-Glutamine Protects against Lipopolysaccharide-Induced Liver Injury in Mice via Alleviating Oxidative Stress, Inhibiting Inflammation, and Regulating Autophagy.
Hu J, Ying H, Zheng Y, Ma H, Li L, Zhao Y
Antioxidants (Basel, Switzerland) 2022 May 27;11(6)
Antioxidants (Basel, Switzerland) 2022 May 27;11(6)
Neural Stem Cell-Derived Exosomal Netrin1 Contributes to Neuron Differentiation of Mesenchymal Stem Cells in Therapy of Spinal Bifida Aperta.
Ma L, Wei X, Ma W, Liu Y, Wang Y, He Y, Jia S, Wang Y, Luo W, Liu D, Huang T, Yan J, Gu H, Bai Y, Yuan Z
Stem cells translational medicine 2022 May 27;11(5):539-551
Stem cells translational medicine 2022 May 27;11(5):539-551
Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages.
Arnan C, Ullrich S, Pulido-Quetglas C, Nurtdinov R, Esteban A, Blanco-Fernandez J, Aparicio-Prat E, Johnson R, Pérez-Lluch S, Guigó R
BMC genomics 2022 May 26;23(1):402
BMC genomics 2022 May 26;23(1):402
Resveratrol pretreatment protects neurons from oxygen-glucose deprivation/reoxygenation and ischemic injury through inhibiting ferroptosis.
Zhu H, Huang J, Chen Y, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Bioscience, biotechnology, and biochemistry 2022 May 24;86(6):704-716
Bioscience, biotechnology, and biochemistry 2022 May 24;86(6):704-716
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Meng Z, Zhu B, Gao M, Wang G, Zhou H, Lu J, Guan S
Food & function 2022 May 23;13(10):5559-5570
Food & function 2022 May 23;13(10):5559-5570
Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia.
Hao C, You J, Qiu H, Zhou O, Liu J, Zou W, Yang K, Fu Z, Zou L
Biochemical and biophysical research communications 2022 May 21;605:111-118
Biochemical and biophysical research communications 2022 May 21;605:111-118
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
Tao X, Zhang R, Du R, Yu T, Yang H, Li J, Wang Y, Liu Q, Zuo S, Wang X, Lazarus M, Zhou L, Wang B, Yu Y, Shen Y
The Journal of experimental medicine 2022 May 2;219(5)
The Journal of experimental medicine 2022 May 2;219(5)
Increased expression of prokineticin 2 and its receptor in endometrium of recurrent implantation failure patients decreased the expression of MMP9 important for decidualization.
Zhai J, Ma L, Chang Z, Yu T
Reproductive biology and endocrinology : RB&E 2022 May 2;20(1):76
Reproductive biology and endocrinology : RB&E 2022 May 2;20(1):76
Chlamydia psittaci Induces Autophagy in Human Bronchial Epithelial Cells via PERK and IRE1α, but Not ATF6 Pathway.
Chen L, Huang Q, Bai Q, Tong T, Zhou Y, Li Z, Xiao C, Chen L
Infection and immunity 2022 May 19;90(5):e0007922
Infection and immunity 2022 May 19;90(5):e0007922
α5-nAChR associated with Ly6E modulates cell migration via TGF-β1/Smad signaling in non-small cell lung cancer.
Zhang Q, Jia Y, Pan P, Zhang X, Jia Y, Zhu P, Chen X, Jiao Y, Kang G, Zhang L, Ma X
Carcinogenesis 2022 May 19;43(4):393-404
Carcinogenesis 2022 May 19;43(4):393-404
G-CSF upregulates the expression of aquaporin-9 through CEBPB to enhance the cytotoxic activity of arsenic trioxide to acute myeloid leukemia cells.
Fu W, Zhu G, Xu L, Liu J, Han X, Wang J, Wang X, Hou J, Zhao H, Zhong H
Cancer cell international 2022 May 19;22(1):195
Cancer cell international 2022 May 19;22(1):195
Comparative Proteomic Analysis Reveals the Effect of Selenoprotein W Deficiency on Oligodendrogenesis in Fear Memory.
Situ J, Huang X, Zuo M, Huang Y, Ren B, Liu Q
Antioxidants (Basel, Switzerland) 2022 May 19;11(5)
Antioxidants (Basel, Switzerland) 2022 May 19;11(5)
Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations.
Ren ZL, Zhang HB, Li L, Yang ZL, Jiang L
Zoological research 2022 May 18;43(3):442-456
Zoological research 2022 May 18;43(3):442-456
Hippocampal NR6A1 impairs CREB-BDNF signaling and leads to the development of depression-like behaviors in mice.
Tan P, Xue T, Wang Y, Hu Z, Su J, Yang R, Ji J, Ye M, Chen Z, Huang C, Lu X
Neuropharmacology 2022 May 15;209:108990
Neuropharmacology 2022 May 15;209:108990
Molecular cloning, characterization, and expression analysis of TIPE1 in chicken (Gallus gallus): Its applications in fatty liver hemorrhagic syndrome.
Cheng X, Liu J, Zhu Y, Guo X, Liu P, Zhang C, Cao H, Xing C, Zhuang Y, Hu G
International journal of biological macromolecules 2022 May 15;207:905-916
International journal of biological macromolecules 2022 May 15;207:905-916
Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration.
Wang M, Zhang Z, Liu J, Song M, Zhang T, Chen Y, Hu H, Yang P, Li B, Song X, Pang J, Xing Y, Cao Z, Guo W, Yang H, Wang J, Yang J, Wang C
Signal transduction and targeted therapy 2022 May 13;7(1):157
Signal transduction and targeted therapy 2022 May 13;7(1):157
Extracellular vesicles from the inflammatory microenvironment regulate the osteogenic and odontogenic differentiation of periodontal ligament stem cells by miR-758-5p/LMBR1/BMP2/4 axis.
Yan C, Li N, Xiao T, Ye X, Fu L, Ye Y, Xu T, Yu J
Journal of translational medicine 2022 May 13;20(1):208
Journal of translational medicine 2022 May 13;20(1):208
Xiao-Luo-Wan treats propylthiouracil-induced goiter with hypothyroidism in rats through the PI3K-AKT/RAS pathways based on UPLC/MS and network pharmacology.
Dong S, Liu Q, Jiang M, Ma Q, Huang Q, Liu T, Li Y, Ni L, Shi Y
Journal of ethnopharmacology 2022 May 10;289:115045
Journal of ethnopharmacology 2022 May 10;289:115045
Network pharmacology analysis uncovers the effect on apoptotic pathway by Bu-Fei formula for COPD treatment.
Zhang LX, Tian YG, Zhao P, Feng SX, Han XX, Li JS
Journal of ethnopharmacology 2022 May 10;289:115022
Journal of ethnopharmacology 2022 May 10;289:115022
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Wang R, Ren Q, Gao D, Paudel YN, Li X, Wang L, Zhang P, Wang B, Shang X, Jin M
Journal of ethnopharmacology 2022 May 10;289:115018
Journal of ethnopharmacology 2022 May 10;289:115018
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Lai R, Ji L, Zhang X, Xu Y, Zhong Y, Chen L, Hu H, Wang L
Molecular and cellular endocrinology 2022 May 1;547:111598
Molecular and cellular endocrinology 2022 May 1;547:111598
Novel variant of ETFDH leading to multiple acyl-CoA dehydrogenase deficiency by promoting protein degradation via ubiquitin proteasome pathway.
Zhang B, Zhao Y
Clinica chimica acta; international journal of clinical chemistry 2022 May 1;530:104-112
Clinica chimica acta; international journal of clinical chemistry 2022 May 1;530:104-112
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Han X, Tang Y, Zhang Y, Zhang J, Hu Z, Xu W, Xu S, Niu Q
Ecotoxicology and environmental safety 2022 May 1;236:113500
Ecotoxicology and environmental safety 2022 May 1;236:113500
Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma.
Feng X, Guo J, An G, Wu Y, Liu Z, Meng B, He N, Zhao X, Chen S, Zhu Y, Xia J, Li X, Yu Z, Li R, Ren G, Chen J, Wu M, He Y, Qiu L, Zhou J, Zhou W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(9):e2104491
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(9):e2104491
Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid.
Liu W, Luo H, Wei Q, Liu J, Wu J, Zhang Y, Chen L, Ren W, Shao L
Bioactive materials 2022 Mar;9:92-104
Bioactive materials 2022 Mar;9:92-104
CD14 Involvement in Third-degree Skin Burn-induced Myocardial Injury via the MAPK Signaling Pathway.
Zhu Z, Zou B, Gao S, Zhang D, Guo J, Chen B, Hou H, Zhu X
Cell biochemistry and biophysics 2022 Mar;80(1):139-150
Cell biochemistry and biophysics 2022 Mar;80(1):139-150
Repair of Spinal Cord Injury by Inhibition of PLK4 Expression Through Local Delivery of siRNA-Loaded Nanoparticles.
Gu Y, Zhang R, Jiang B, Xu X, Guan JJ, Jiang XJ, Zhou Y, Zhou YL, Chen X
Journal of molecular neuroscience : MN 2022 Mar;72(3):544-554
Journal of molecular neuroscience : MN 2022 Mar;72(3):544-554
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.
Meng B, Abdullahi A, Ferreira IATM, Goonawardane N, Saito A, Kimura I, Yamasoba D, Gerber PP, Fatihi S, Rathore S, Zepeda SK, Papa G, Kemp SA, Ikeda T, Toyoda M, Tan TS, Kuramochi J, Mitsunaga S, Ueno T, Shirakawa K, Takaori-Kondo A, Brevini T, Mallery DL, Charles OJ, CITIID-NIHR BioResource COVID-19 Collaboration, Genotype to Phenotype Japan (G2P-Japan) Consortium, Ecuador-COVID19 Consortium, Bowen JE, Joshi A, Walls AC, Jackson L, Martin D, Smith KGC, Bradley J, Briggs JAG, Choi J, Madissoon E, Meyer KB, Mlcochova P, Ceron-Gutierrez L, Doffinger R, Teichmann SA, Fisher AJ, Pizzuto MS, de Marco A, Corti D, Hosmillo M, Lee JH, James LC, Thukral L, Veesler D, Sigal A, Sampaziotis F, Goodfellow IG, Matheson NJ, Sato K, Gupta RK
Nature 2022 Mar;603(7902):706-714
Nature 2022 Mar;603(7902):706-714
Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression.
Chen J, Li K, Chen J, Wang X, Ling R, Cheng M, Chen Z, Chen F, He Q, Li S, Zhang C, Jiang Y, Chen Q, Wang A, Chen D
Cancer communications (London, England) 2022 Mar;42(3):223-244
Cancer communications (London, England) 2022 Mar;42(3):223-244
M(6)A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression.
Lv D, Ding S, Zhong L, Tu J, Li H, Yao H, Zou Y, Zeng Z, Liao Y, Wan X, Wen L, Xie X
Oncogene 2022 Mar;41(12):1727-1741
Oncogene 2022 Mar;41(12):1727-1741
2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis in mice by interfering with the ER-Nrf1-Tfam-mitochondria pathway.
Huang S, Xia J, Zhang X, Zhou T, Wang J, Liu T, Xu S, Liang G
Toxicology and industrial health 2022 Mar;38(3):182-191
Toxicology and industrial health 2022 Mar;38(3):182-191
Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy.
Huang X, Wu W, Jing D, Yang L, Guo H, Wang L, Zhang W, Pu F, Shao Z
Journal of controlled release : official journal of the Controlled Release Society 2022 Mar;343:107-117
Journal of controlled release : official journal of the Controlled Release Society 2022 Mar;343:107-117
Acetylation-dependent SAGA complex dimerization promotes nucleosome acetylation and gene transcription.
Huang J, Dai W, Xiao D, Xiong Q, Liu C, Hu J, Ge F, Yu X, Li S
Nature structural & molecular biology 2022 Mar;29(3):261-273
Nature structural & molecular biology 2022 Mar;29(3):261-273
SRSF3 facilitates replication of influenza A virus via binding and promoting the transport of viral mRNA.
Zhao L, Li Y, Zhao Y, Liu Q, Lu Y, Ping J
Veterinary microbiology 2022 Mar;266:109343
Veterinary microbiology 2022 Mar;266:109343
Lysophosphatidic acid receptor 6 regulated by miR-27a-3p attenuates tumor proliferation in breast cancer.
Lei J, Guo S, Li K, Tian J, Zong B, Ai T, Peng Y, Zhang Y, Liu S
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Mar;24(3):503-516
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Mar;24(3):503-516
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Xu Y, Shi H, Wang M, Huang P, Xu M, Han S, Li H, Wang Y
Experimental and therapeutic medicine 2022 Mar;23(3):247
Experimental and therapeutic medicine 2022 Mar;23(3):247
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
Lin T, Tao J, Chen Y, Zhang Y, Li F, Zhang Y, Han X, Zhao Z, Liu G, Li H
Biological trace element research 2022 Mar;200(3):1127-1139
Biological trace element research 2022 Mar;200(3):1127-1139
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Ren X, Lv J, Wang N, Liu J, Gao C, Wu X, Yu Y, Teng Q, Dong W, Kong H, Kong L
Diabetes research and clinical practice 2022 Mar;185:109788
Diabetes research and clinical practice 2022 Mar;185:109788
Immune-responsive gene 1 protects against liver injury caused by concanavalin A via the activation Nrf2/HO-1 pathway and inhibition of ROS activation pathways.
Yang W, Wang Y, Zhang P, Sun X, Chen X, Yu J, Shi L, Yin Y, Tao K, Li R
Free radical biology & medicine 2022 Mar;182:108-118
Free radical biology & medicine 2022 Mar;182:108-118
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
Li Y, Jiang Y, Zhou W, Wu Y, Zhang S, Ding G, Zhang Y, Zhang A, Huang S, Jia Z, You R
Free radical biology & medicine 2022 Mar;181:270-287
Free radical biology & medicine 2022 Mar;181:270-287
Inhibition of ROCK2 kinase activity improved behavioral deficits and reduced neuron damage in a DEACMP rat model.
Xu L, Liu X, Guo C, Wang C, Zhao J, Zhang X, Li W, Zhang P, Gu R
Brain research bulletin 2022 Mar;180:24-30
Brain research bulletin 2022 Mar;180:24-30
SNF5, a core subunit of SWI/SNF complex, regulates melanoma cancer cell growth, metastasis, and immune escape in response to matrix stiffness.
Chen Y, Zhao M, Zhang L, Shen D, Xu X, Yi Q, Tang L
Translational oncology 2022 Mar;17:101335
Translational oncology 2022 Mar;17:101335
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression.
Ren D, Sun Y, Li D, Wu H, Jin X
Molecular oncology 2022 Mar;16(5):1200-1217
Molecular oncology 2022 Mar;16(5):1200-1217
Secreted gingipains from Porphyromonas gingivalis increase permeability in human cerebral microvascular endothelial cells through intracellular degradation of tight junction proteins.
Nonaka S, Kadowaki T, Nakanishi H
Neurochemistry international 2022 Mar;154:105282
Neurochemistry international 2022 Mar;154:105282
Caecal microbiota could effectively increase chicken growth performance by regulating fat metabolism.
Zhang X, Hu Y, Ansari AR, Akhtar M, Chen Y, Cheng R, Cui L, Nafady AA, Elokil AA, Abdel-Kafy EM, Liu H
Microbial biotechnology 2022 Mar;15(3):844-861
Microbial biotechnology 2022 Mar;15(3):844-861
Ablation of Plasma Prekallikrein Decreases Low-Density Lipoprotein Cholesterol by Stabilizing Low-Density Lipoprotein Receptor and Protects Against Atherosclerosis.
Wang JK, Li Y, Zhao XL, Liu YB, Tan J, Xing YY, Adi D, Wang YT, Fu ZY, Ma YT, Liu SM, Liu Y, Wang Y, Shi XJ, Lu XY, Song BL, Luo J
Circulation 2022 Mar;145(9):675-687
Circulation 2022 Mar;145(9):675-687
Rab31 promotes activation of hepatic stellate cells by accelerating TGF-β receptor II complex endocytosis.
Qiu C, Liu Y, Huang S, Ning B, He S, Zhong L
The international journal of biochemistry & cell biology 2022 Mar;144:106170
The international journal of biochemistry & cell biology 2022 Mar;144:106170
IL-10 Dysregulation Underlies Chemokine Insufficiency, Delayed Macrophage Response, and Impaired Healing in Diabetic Wounds.
Roy R, Zayas J, Mohamed MF, Aboonabi A, Delgado K, Wallace J, Bayat M, Kuzel TM, Reiser J, Shafikhani SH
The Journal of investigative dermatology 2022 Mar;142(3 Pt A):692-704.e14
The Journal of investigative dermatology 2022 Mar;142(3 Pt A):692-704.e14
Corresponding Changes of Autophagy-Related Genes and Proteins in Different Stages of Knee Osteoarthritis: An Animal Model Study.
Zhang SL, Zhang KS, Wang JF, Wang YC, Zhang H, Tang C, Pei Z, Guan ZP
Orthopaedic surgery 2022 Mar;14(3):595-604
Orthopaedic surgery 2022 Mar;14(3):595-604
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Li H, You S, Yang X, Liu S, Hu L
Biomaterials advances 2022 Mar;134:112715
Biomaterials advances 2022 Mar;134:112715
Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2.
Wang Z, Qi G, Li Z, Cui X, Guo S, Zhang Y, Cai P, Wang X
Bioengineered 2022 Mar;13(3):5064-5078
Bioengineered 2022 Mar;13(3):5064-5078
The effects of modified RNA-binding proteins HuR on the biological behavior of the bladder cancer T24 cell line.
Ma Q, Xu C, Han X, Wang X, Zhang W, Liu Z, Wu R, Wu F, Liu X, Zhang T, Su Y, Zheng K, Wang Y
Translational andrology and urology 2022 Mar;11(3):348-357
Translational andrology and urology 2022 Mar;11(3):348-357
Dopamine D3 receptor in the nucleus accumbens alleviates neuroinflammation in a mouse model of depressive-like behavior.
Wang J, Lai S, Wang R, Zhou T, Dong N, Zhu L, Chen T, Zhang X, Chen Y
Brain, behavior, and immunity 2022 Mar;101:165-179
Brain, behavior, and immunity 2022 Mar;101:165-179
Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn's disease.
Xie X, Qu P, Wu H, Liu P, Luo J, Chi J, Liu X, Chen X, Xu C
Annals of translational medicine 2022 Mar;10(5):258
Annals of translational medicine 2022 Mar;10(5):258
Peritoneal dialysis effluent-derived exosomal miR-432-5p: an assessment tool for peritoneal dialysis efficacy.
Tong Y, Fang JY, Song AH, Deng H, Li P, Huang ZH, Ji OY, Ge XL, Zhu TY, Liu YL
Annals of translational medicine 2022 Mar;10(5):242
Annals of translational medicine 2022 Mar;10(5):242
Trimetazidine and exercise offer analogous improvements to the skeletal muscle insulin resistance of mice through Nrf2 signaling.
Zhang W, Dun Y, You B, Qiu L, Ripley-Gonzalez JW, Cheng J, Fu S, Li C, Liu S
BMJ open diabetes research & care 2022 Mar;10(2)
BMJ open diabetes research & care 2022 Mar;10(2)
Novel insights into the mechanisms by which lncRNA HOTAIR regulates migration and invasion in HeLa cells.
Zheng P, Wu Y, Chen Y, Chen Z, Zhang T
Cell cycle (Georgetown, Tex.) 2022 Mar-Mar;21(6):602-617
Cell cycle (Georgetown, Tex.) 2022 Mar-Mar;21(6):602-617
Human Cytomegalovirus Hijacks WD Repeat Domain 11 for Virion Assembly Compartment Formation and Virion Morphogenesis.
Yang B, Yao Y, Cheng H, Wang XZ, Zhou YP, Huang SN, Ma X, Yang H, Wu J, Jiang X, Cheng S, Sun JY, Zeng WB, Chen J, Zhang FK, Shen HJ, Gu JY, McVoy MA, Britt WJ, Gong S, Luo MH
Journal of virology 2022 Mar 9;96(5):e0182721
Journal of virology 2022 Mar 9;96(5):e0182721
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8(+) T cell responses.
Banta KL, Xu X, Chitre AS, Au-Yeung A, Takahashi C, O'Gorman WE, Wu TD, Mittman S, Cubas R, Comps-Agrar L, Fulzele A, Bennett EJ, Grogan JL, Hui E, Chiang EY, Mellman I
Immunity 2022 Mar 8;55(3):512-526.e9
Immunity 2022 Mar 8;55(3):512-526.e9
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Wang T, Xu J, Xu Y, Xiao J, Bi N, Gu X, Wang HL
Cell reports 2022 Mar 8;38(10):110478
Cell reports 2022 Mar 8;38(10):110478
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Zeng L, Jiang H, Ashraf GM, Liu J, Wang L, Zhao K, Liu M, Li Z, Liu R
Molecular therapy. Nucleic acids 2022 Mar 8;27:256-275
Molecular therapy. Nucleic acids 2022 Mar 8;27:256-275
Bergamottin promotes osteoblast differentiation and bone formation via activating the Wnt/β-catenin signaling pathway.
Wang X, Tian Y, Liang X, Yin C, Huai Y, Zhao Y, Huang Q, Chu X, Wang W, Qian A
Food & function 2022 Mar 7;13(5):2913-2924
Food & function 2022 Mar 7;13(5):2913-2924
Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 male mice.
Cui Y, Yin Y, Li S, Wu Z, Xie Y, Qian Q, Yang H, Li X
Food & function 2022 Mar 7;13(5):2805-2822
Food & function 2022 Mar 7;13(5):2805-2822
Bisphenol A drives di(2-ethylhexyl) phthalate promoting thyroid tumorigenesis via regulating HDAC6/PTEN and c-MYC signaling.
Zhang X, Guo N, Jin H, Liu R, Zhang Z, Cheng C, Fan Z, Zhang G, Xiao M, Wu S, Zhao Y, Lu X
Journal of hazardous materials 2022 Mar 5;425:127911
Journal of hazardous materials 2022 Mar 5;425:127911
Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.
Tian C, Zhang G, Xia Z, Chen N, Yang S, Li L
European journal of medicinal chemistry 2022 Mar 5;231:114122
European journal of medicinal chemistry 2022 Mar 5;231:114122
Loss of NPPA-AS1 promotes heart regeneration by stabilizing SFPQ-NONO heteromer-induced DNA repair.
Fu W, Ren H, Shou J, Liao Q, Li L, Shi Y, Jose PA, Zeng C, Wang WE
Basic research in cardiology 2022 Mar 5;117(1):10
Basic research in cardiology 2022 Mar 5;117(1):10
miR-30a targets STOX2 to increase cell proliferation and metastasis in hydatidiform moles via ERK, AKT, and P38 signaling pathways.
Guo Z, Zhu C, Wang Y, Li Z, Wang L, Fan J, Xu Y, Zou N, Kong Y, Li D, Sui L
Cancer cell international 2022 Mar 4;22(1):103
Cancer cell international 2022 Mar 4;22(1):103
Mdivi-1 alleviates cardiac fibrosis post myocardial infarction at infarcted border zone, possibly via inhibition of Drp1-Activated mitochondrial fission and oxidative stress.
Ding J, Zhang Z, Li S, Wang W, Du T, Fang Q, Wang Y, Wang DW
Archives of biochemistry and biophysics 2022 Mar 30;718:109147
Archives of biochemistry and biophysics 2022 Mar 30;718:109147
N-methyl-D-aspartic acid increases tight junction protein destruction in brain endothelial cell via caveolin-1-associated ERK1/2 signaling.
Mao F, Huang F, Nong W, Lao D, Gong Z, Huang W
Toxicology 2022 Mar 30;470:153139
Toxicology 2022 Mar 30;470:153139
Gene knockdown of CCR3 reduces eosinophilic inflammation and the Th2 immune response by inhibiting the PI3K/AKT pathway in allergic rhinitis mice.
Yuan J, Liu Y, Yu J, Dai M, Zhu Y, Bao Y, Peng H, Liu K, Zhu X
Scientific reports 2022 Mar 30;12(1):5411
Scientific reports 2022 Mar 30;12(1):5411
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex.
Han C, Sun LY, Luo XQ, Pan Q, Sun YM, Zeng ZC, Chen TQ, Huang W, Fang K, Wang WT, Chen YQ
Cell reports 2022 Mar 29;38(13):110421
Cell reports 2022 Mar 29;38(13):110421
Integrative analysis of DNA methylation and gene expression reveals key molecular signatures in acute myocardial infarction.
Luo X, Hu Y, Shen J, Liu X, Wang T, Li L, Li J
Clinical epigenetics 2022 Mar 27;14(1):46
Clinical epigenetics 2022 Mar 27;14(1):46
The "LLQY" Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles.
Du S, Xu W, Wang Y, Li L, Hao P, Tian M, Wang M, Li T, Wu S, Liu Q, Bai J, Qu X, Jin N, Zhou B, Liao M, Li C
Journal of virology 2022 Mar 23;96(6):e0189721
Journal of virology 2022 Mar 23;96(6):e0189721
Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells.
Liu C, Lin C, Wang D, Wang J, Tao Y, Li Y, Chen X, Bai L, Jia Y, Chen J, Zeng YA
Cell reports 2022 Mar 22;38(12):110548
Cell reports 2022 Mar 22;38(12):110548
Antibody-drug conjugates targeting CD248 inhibits liver fibrosis through specific killing on myofibroblasts.
Liu S, Han D, Xu C, Yang F, Li Y, Zhang K, Zhao X, Zhang J, Lu T, Lu S, Shi C, Zhang R, Yang AG, Zhao A, Qin W, Yang B, Wen W
Molecular medicine (Cambridge, Mass.) 2022 Mar 22;28(1):37
Molecular medicine (Cambridge, Mass.) 2022 Mar 22;28(1):37
A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling.
Tanuma SI, Oyama T, Okazawa M, Yamazaki H, Takao K, Sugita Y, Amano S, Abe T, Sakagami H
International journal of molecular sciences 2022 Mar 22;23(7)
International journal of molecular sciences 2022 Mar 22;23(7)
CRISPR-iPAS: a novel dCAS13-based method for alternative polyadenylation interference.
Tian S, Zhang B, He Y, Sun Z, Li J, Li Y, Yi H, Zhao Y, Zou X, Li Y, Cui H, Fang L, Gao X, Hu Y, Chen W
Nucleic acids research 2022 Mar 21;50(5):e26
Nucleic acids research 2022 Mar 21;50(5):e26
Excess iodide-induced reactive oxygen species elicit iodide efflux via β-tubulin-associated ClC-3 in thyrocytes.
Yu M, Wei Y, Wang P, Deng Z, Mao J, Zhu L, Chen L, Peng S, Wang L
The Biochemical journal 2022 Mar 18;479(5):629-640
The Biochemical journal 2022 Mar 18;479(5):629-640
Long noncoding RNA Lnc-DIF inhibits bone formation by sequestering miR-489-3p.
Yin C, Tian Y, Li D, Yu Y, Jiang S, Hou Y, Deng M, Zheng K, Zhang Y, Deng X, Chen Z, Miao Z, Hao Q, Li Y, Qian A
iScience 2022 Mar 18;25(3):103949
iScience 2022 Mar 18;25(3):103949
Cholesterol promotes EGFR-TKIs resistance in NSCLC by inducing EGFR/Src/Erk/SP1 signaling-mediated ERRα re-expression.
Pan Z, Wang K, Wang X, Jia Z, Yang Y, Duan Y, Huang L, Wu ZX, Zhang JY, Ding X
Molecular cancer 2022 Mar 18;21(1):77
Molecular cancer 2022 Mar 18;21(1):77
USP49-Mediated Histone H2B Deubiquitination Regulates HCT116 Cell Proliferation through MDM2-p53 Axis.
Shi L, Shen X, Shen Y
Molecular and cellular biology 2022 Mar 17;42(3):e0043421
Molecular and cellular biology 2022 Mar 17;42(3):e0043421
Hsa_circ_0001666 promotes non-small cell lung cancer migration and invasion through miR-1184/miR-548I/AGO1 axis.
Wang X, Li R, Feng L, Wang J, Qi Q, Wei W, Yu Z
Molecular therapy oncolytics 2022 Mar 17;24:597-611
Molecular therapy oncolytics 2022 Mar 17;24:597-611
Risk subtyping and prognostic assessment of prostate cancer based on consensus genes.
Meng J, Guan Y, Wang B, Chen L, Chen J, Zhang M, Liang C
Communications biology 2022 Mar 15;5(1):233
Communications biology 2022 Mar 15;5(1):233
The role of α5-nicotinic acetylcholine receptor/NLRP3 signaling pathway in lung adenocarcinoma cell proliferation and migration.
Jia Y, Zhang Q, Liu Z, Pan P, Jia Y, Zhu P, Jiao Y, Kang G, Ma X
Toxicology 2022 Mar 15;469:153120
Toxicology 2022 Mar 15;469:153120
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Shi H, Zhang Y, Wang Y, Fang P, Liu Y, Li W
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Protective role of mRNA demethylase FTO on axon guidance molecules of nigro-striatal projection system in manganese-induced parkinsonism.
Qi Z, Wang S, Li J, Wen Y, Cui R, Zhang K, Liu Y, Yang X, Zhang L, Xu B, Liu W, Xu Z, Deng Y
Journal of hazardous materials 2022 Mar 15;426:128099
Journal of hazardous materials 2022 Mar 15;426:128099
Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.
Jiao Y, Nan J, Mu B, Zhang Y, Zhou N, Yang S, Zhang S, Lin W, Wang F, Xia A, Cao Z, Chen P, Pan Z, Lin G, Pan S, Bin H, Li L, Yang S
European journal of medicinal chemistry 2022 Mar 15;232:114194
European journal of medicinal chemistry 2022 Mar 15;232:114194
Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.
Ye N, Lv Z, Huang Z, Cheng Y, Wei Q, Shi F
Theriogenology 2022 Mar 15;181:8-15
Theriogenology 2022 Mar 15;181:8-15
LMBR1L regulates the proliferation and migration of endothelial cells through Norrin/β-catenin signaling.
Liu W, Jiang X, Li X, Sun K, Yang Y, Yang M, Li S, Zhu X
Journal of cell science 2022 Mar 15;135(6)
Journal of cell science 2022 Mar 15;135(6)
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
He Z, Cai K, Zeng Z, Lei S, Cao W, Li X
Cell death & disease 2022 Mar 14;13(3):233
Cell death & disease 2022 Mar 14;13(3):233
Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer.
Zhang Y, Sun L, Li H, Ai L, Ma Q, Qiao X, Yang J, Zhang H, Ou X, Wang Y, Chen G, Xue J, Zhu X, Zhao Y, Yang Y, Liu C
eLife 2022 Mar 14;11
eLife 2022 Mar 14;11
Inhibition of microRNA-448 suppresses CD4(+) T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus.
Zhang J, Guo Y, Sun Y, Chang L, Wang X
Biochemical and biophysical research communications 2022 Mar 12;596:88-96
Biochemical and biophysical research communications 2022 Mar 12;596:88-96
CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT.
Mohamed MF, Gupta K, Goldufsky JW, Roy R, Callaghan LT, Wetzel DM, Kuzel TM, Reiser J, Shafikhani SH
Nature communications 2022 Mar 11;13(1):1295
Nature communications 2022 Mar 11;13(1):1295
LncRNA RP5-998N21.4 promotes immune defense through upregulation of IFIT2 and IFIT3 in schizophrenia.
Guo B, Jiang T, Wu F, Ni H, Ye J, Wu X, Ni C, Jiang M, Ye L, Li Z, Zheng X, Li S, Yang Q, Wang Z, Huang X, Zhao C
Schizophrenia (Heidelberg, Germany) 2022 Mar 1;8(1):11
Schizophrenia (Heidelberg, Germany) 2022 Mar 1;8(1):11
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
Zhang Y, Wu Z, Huang Z, Liu Y, Chen X, Zhao X, He H, Deng Y
Brain research 2022 Mar 1;1778:147768
Brain research 2022 Mar 1;1778:147768
PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence.
Singh CK, Denu RA, Nihal M, Shabbir M, Garvey DR, Huang W, Iczkowski KA, Ahmad N
The Prostate 2022 Jun;82(9):957-969
The Prostate 2022 Jun;82(9):957-969
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Xie M, Xiong Z, Yin S, Xiong J, Li X, Jin L, Zhang F, Chen H, Lan P, Lian L
Digestive diseases and sciences 2022 Jun;67(6):2232-2243
Digestive diseases and sciences 2022 Jun;67(6):2232-2243
Inclisiran inhibits oxidized low-density lipoprotein-induced foam cell formation in Raw264.7 macrophages via activating the PPARγ pathway.
Wang Z, Chen X, Liu J, Wang Y, Zhang S
Autoimmunity 2022 Jun;55(4):223-232
Autoimmunity 2022 Jun;55(4):223-232
The nuclear receptor REV-ERBα regulates CYP2E1 expression and acetaminophen hepatotoxicity.
Zhang L, Zhang F, Xiao Y, Du J, Zhang X, Chen M, Wu B
Xenobiotica; the fate of foreign compounds in biological systems 2022 Jun;52(6):633-643
Xenobiotica; the fate of foreign compounds in biological systems 2022 Jun;52(6):633-643
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Wu WY, Wang ZX, Li TS, Ding XQ, Liu ZH, Yang J, Fang L, Kong LD
Redox biology 2022 Jun;52:102303
Redox biology 2022 Jun;52:102303
Novel insights for PI3KC3 in mediating lipid accumulation in yellow catfish Pelteobagrus fulvidraco.
Zhuo MQ, Chen J, Wu ML, Wang WB
Fish physiology and biochemistry 2022 Jun;48(3):571-583
Fish physiology and biochemistry 2022 Jun;48(3):571-583
In Vivo and In Vitro Fibroblasts' Behavior and Capsular Formation in Correlation with Smooth and Textured Silicone Surfaces.
Huang SQ, Chen Y, Zhu Q, Zhang YM, Lei ZY, Zhou X, Fan DL
Aesthetic plastic surgery 2022 Jun;46(3):1164-1177
Aesthetic plastic surgery 2022 Jun;46(3):1164-1177
TRIM32 Inhibition Attenuates Apoptosis, Oxidative Stress, and Inflammatory Injury in Podocytes Induced by High Glucose by Modulating the Akt/GSK-3β/Nrf2 Pathway.
Chen Z, Tian L, Wang L, Ma X, Lei F, Chen X, Fu R
Inflammation 2022 Jun;45(3):992-1006
Inflammation 2022 Jun;45(3):992-1006
Histone H3K9 methyltransferase SETDB1 augments invadopodia formation to promote tumor metastasis.
Ueshima S, Fang J
Oncogene 2022 Jun;41(24):3370-3380
Oncogene 2022 Jun;41(24):3370-3380
LncRNA small nucleolar RNA host gene 16 reduces sepsis-induced myocardial damage by regulating miR-421/suppressor of cytokine signaling 5 axis.
Yu M, Xie D, Hu CY, Cui Y
The Kaohsiung journal of medical sciences 2022 Jun;38(6):517-529
The Kaohsiung journal of medical sciences 2022 Jun;38(6):517-529
Restraint of FAM60A has a cancer-inhibiting role in pancreatic carcinoma via the effects on the Akt/GSK-3β/β-catenin signaling pathway.
Zhang Y, Li JH, Yuan QG, Yang WB
Environmental toxicology 2022 Jun;37(6):1432-1444
Environmental toxicology 2022 Jun;37(6):1432-1444
Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.
Hao W, Zhu X, Liu Z, Song Y, Wu S, Lu X, Yang J, Jin C
Environmental toxicology 2022 Jun;37(6):1373-1381
Environmental toxicology 2022 Jun;37(6):1373-1381
Protective effect of C-phycocyanin and apo-phycocyanin subunit on programmed necrosis of GC-1 spg cells induced by H(2) O(2).
Dong X, Yang F, Xu X, Zhu F, Liu G, Xu F, Chen G, Cao C, Teng L, Li X, Wang L, Li B
Environmental toxicology 2022 Jun;37(6):1275-1287
Environmental toxicology 2022 Jun;37(6):1275-1287
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Wang Z, Liang M, Liu B, Yang L
Food science and biotechnology 2022 Jun;31(6):745-758
Food science and biotechnology 2022 Jun;31(6):745-758
MicroRNA-139-5p negatively regulates NME1 expression in hepatocellular carcinoma cells.
Yang J, Li Z, Pang Y, Zhou T, Sun J, Cheng XY, Zheng WV
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jun;31(6):655-670
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jun;31(6):655-670
Microtubule depolymerization limits porcine betacoronavirus PHEV replication.
Zhou Q, Lan Y, Tang Y, Guan J, Zhao K, Gao F, He W, Li Z
Veterinary microbiology 2022 Jun;269:109448
Veterinary microbiology 2022 Jun;269:109448
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Wu Y, Qian J, Li K, Li W, Yin W, Jiang H
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice.
Zhang H, Wu X, Tao Y, Lu G
Experimental and therapeutic medicine 2022 Jun;23(6):371
Experimental and therapeutic medicine 2022 Jun;23(6):371
Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis.
Wang Y, Liao S, Pan Z, Jiang S, Fan J, Yu S, Xue L, Yang J, Ma S, Liu T, Zhang J, Chen Y
Free radical biology & medicine 2022 Jun;186:1-16
Free radical biology & medicine 2022 Jun;186:1-16
Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion mice.
Zhu J, Jin Z, Yang L, Zhao C, Hu J, Chen J, Han Y, Yu P, Luo J, Kong L, Zhang C
Pharmacological research 2022 Jun;180:106240
Pharmacological research 2022 Jun;180:106240
Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival.
Song Y, Ge X, Chen Y, Hussain T, Liang Z, Dong Y, Wang Y, Tang C, Zhou X
Autophagy 2022 Jun;18(6):1401-1415
Autophagy 2022 Jun;18(6):1401-1415
The crucial role of thioredoxin interacting protein in the liver insulin resistance induced by di (2-ethylhexyl) phthalates.
Zhang W, Xu P, Li JY
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113045
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113045
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Ren K, He J, Qiu Y, Xu Z, Wang X, Li J, Zang S, Yang Y, Li J, Long Y, Zhang Z, Li M, He Q
Acta biomaterialia 2022 Jun;145:185-199
Acta biomaterialia 2022 Jun;145:185-199
Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.
Yu Y, Bian Y, Shi JX, Gu Y, Yuan DP, Yu B, Shi L, Dou DH
Bioengineered 2022 Jun;13(6):14616-14631
Bioengineered 2022 Jun;13(6):14616-14631
Identity of MMP1 and its effects on tumor progression in head and neck squamous cell carcinoma.
Zhang G, Li T, Tan G, Song Y, Liu Q, Wang K, Ai J, Zhou Z, Li W
Cancer medicine 2022 Jun;11(12):2516-2530
Cancer medicine 2022 Jun;11(12):2516-2530
α(1) -Adrenoceptors activate the NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation.
Chen L, Wang W, Peng X, Liu L, Zhang A, Li X, Ma K, Wang L
Experimental physiology 2022 Jun;107(6):589-600
Experimental physiology 2022 Jun;107(6):589-600
Exercise training improves cardiac function and regulates myocardial mitophagy differently in ischaemic and pressure-overload heart failure mice.
Guo C, Chen MJ, Zhao JR, Wu RY, Zhang Y, Li QQ, Zhao H, Dou JH, Song SF, Wei J
Experimental physiology 2022 Jun;107(6):562-574
Experimental physiology 2022 Jun;107(6):562-574
SIRT1 alleviates IL-1β induced nucleus pulposus cells pyroptosis via mitophagy in intervertebral disc degeneration.
Ma Z, Tang P, Dong W, Lu Y, Tan B, Zhou N, Hao J, Shen J, Hu Z
International immunopharmacology 2022 Jun;107:108671
International immunopharmacology 2022 Jun;107:108671
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Zhong T, Li M, Wu H, Wang D, Liu J, Xu Y, Fan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
A novel frameshift variant in the TSPAN12 gene causes autosomal dominant FEVR.
Peng L, Dai E, Xiao H, Zhao R, He Y, Li S, Yang M, Yang Z, Zhao P
Molecular genetics & genomic medicine 2022 Jun;10(6):e1949
Molecular genetics & genomic medicine 2022 Jun;10(6):e1949
Interleukin-20 is involved in dry eye disease and is a potential therapeutic target.
Wang HH, Chen WY, Huang YH, Hsu SM, Tsao YP, Hsu YH, Chang MS
Journal of biomedical science 2022 Jun 9;29(1):36
Journal of biomedical science 2022 Jun 9;29(1):36
A Single Amino Acid Substitution in RFC4 Leads to Endoduplication and Compromised Resistance to DNA Damage in Arabidopsis thaliana.
Cui K, Qin L, Tang X, Nong J, Chen J, Wu N, Gong X, Yi L, Yang C, Xia S
Genes 2022 Jun 9;13(6)
Genes 2022 Jun 9;13(6)
Suppression of axonal attractant netrin-1 injured dopaminergic neuronal and motor function of mice during manganese overexposure.
Wen Y, Qi Z, Li J, Zhang L, Wang S, Cui R, Xu B, Liu W, Xu Z, Deng Y
Metallomics : integrated biometal science 2022 Jun 8;14(6)
Metallomics : integrated biometal science 2022 Jun 8;14(6)
A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency.
Huang X, Bashkenova N, Hong Y, Lyu C, Guallar D, Hu Z, Malik V, Li D, Wang H, Shen X, Zhou H, Wang J
Cell reports 2022 Jun 7;39(10):110928
Cell reports 2022 Jun 7;39(10):110928
Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ.
Ouyang M, Ouyang X, Peng Z, Liu M, Xu G, Zou Z, Zhang M, Shang Q
Journal of nanobiotechnology 2022 Jun 7;20(1):263
Journal of nanobiotechnology 2022 Jun 7;20(1):263
Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis.
Zhou Z, Shu Y, Bao H, Han S, Liu Z, Zhao N, Yuan W, Jian C, Shu X
Journal of translational medicine 2022 Jun 7;20(1):262
Journal of translational medicine 2022 Jun 7;20(1):262
The Molecular Mechanism of Long Non-Coding RNA MALAT1-Mediated Regulation of Chondrocyte Pyroptosis in Ankylosing Spondylitis.
Chen W, Wang F, Wang J, Chen F, Chen T
Molecules and cells 2022 Jun 30;45(6):365-375
Molecules and cells 2022 Jun 30;45(6):365-375
G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation.
Zhang F, Lei L, Huang J, Wang W, Su Q, Yan H, Chen C, Zheng S, Ren H, Li Z, Jose PA, Hu Y, Si L, Zeng C, Yang J
Clinical science (London, England : 1979) 2022 Jun 30;136(12):989-1003
Clinical science (London, England : 1979) 2022 Jun 30;136(12):989-1003
Postnatal Cytomegalovirus Infection May Increase the Susceptibility of Tuberous Sclerosis Complex to Autism Spectrum Disorders.
Yang XY, Wang YY, Zhou YP, He J, Mei MJ, Zhang MN, Wang B, Zhou WJ, Luo MH, Wang QH, Li ZY, Xu Y, Lu Q, Zou LP
Microbiology spectrum 2022 Jun 29;10(3):e0186421
Microbiology spectrum 2022 Jun 29;10(3):e0186421
DDX5/METTL3-METTL14/YTHDF2 Axis Regulates Replication of Influenza A Virus.
Zhao L, Zhao Y, Liu Q, Huang J, Lu Y, Ping J
Microbiology spectrum 2022 Jun 29;10(3):e0109822
Microbiology spectrum 2022 Jun 29;10(3):e0109822
GALNT12 is associated with the malignancy of glioma and promotes glioblastoma multiforme in vitro by activating Akt signaling.
Zheng Y, Liang M, Wang B, Kang L, Yuan Y, Mao Y, Wang S
Biochemical and biophysical research communications 2022 Jun 25;610:99-106
Biochemical and biophysical research communications 2022 Jun 25;610:99-106
CaMKII and Kalirin, a Rac1-GEF, regulate Akt phosphorylation involved in contraction-induced glucose uptake in skeletal muscle cells.
Liu S, Zhang J, Qi R, Deng B, Ni Y, Zhang C, Niu W
Biochemical and biophysical research communications 2022 Jun 25;610:170-175
Biochemical and biophysical research communications 2022 Jun 25;610:170-175
The Expression and Role Analysis of Methylation-Regulated Differentially Expressed Gene UBE2C in Pan-Cancer, Especially for HGSOC.
Li J, Sun Y, Zhi X, Li Q, Yao L, Chen M
Cancers 2022 Jun 25;14(13)
Cancers 2022 Jun 25;14(13)
CRISPR/Cas13 effectors have differing extents of off-target effects that limit their utility in eukaryotic cells.
Ai Y, Liang D, Wilusz JE
Nucleic acids research 2022 Jun 24;50(11):e65
Nucleic acids research 2022 Jun 24;50(11):e65
Alu RNA induces NLRP3 expression through TLR7 activation in α-1-antitrypsin-deficient macrophages.
Lee J, Mohammad N, Lu Y, Kang K, Han K, Brantly M
JCI insight 2022 Jun 22;7(12)
JCI insight 2022 Jun 22;7(12)
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.
Chen Z, Wu H, Yang J, Li B, Ding J, Cheng S, Bsoul N, Zhang C, Li J, Liu H, Lin D, Gao W
Communications biology 2022 Jun 22;5(1):616
Communications biology 2022 Jun 22;5(1):616
Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
Terry BK, Park R, Cho SH, Crino PB, Kim S
Human molecular genetics 2022 Jun 22;31(12):1979-1996
Human molecular genetics 2022 Jun 22;31(12):1979-1996
Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells.
Jin M, Shirazinejad C, Wang B, Yan A, Schöneberg J, Upadhyayula S, Xu K, Drubin DG
Nature communications 2022 Jun 22;13(1):3578
Nature communications 2022 Jun 22;13(1):3578
Structural characterization of a dimerization interface in the CD28 transmembrane domain.
Wu H, Cao R, Wen M, Xue H, OuYang B
Structure (London, England : 1993) 2022 Jun 2;30(6):803-812.e5
Structure (London, England : 1993) 2022 Jun 2;30(6):803-812.e5
Perfluorooctane sulfonate induces mitochondrial calcium overload and early hepatic insulin resistance via autophagy/detyrosinated alpha-tubulin-regulated IP3R2-VDAC1-MICU1 interaction.
Dong Z, Wang J, Qiu T, Wu J, An Y, Shi X, Sun X, Jiang L, Liu X, Yang G, Cao J, Yao X
The Science of the total environment 2022 Jun 15;825:153933
The Science of the total environment 2022 Jun 15;825:153933
Inhibition of Nicotinamide adenine dinucleotide phosphate oxidase 4 attenuates cell apoptosis and oxidative stress in a rat model of polycystic ovary syndrome through the activation of Nrf-2/HO-1 signaling pathway.
Li Y, Xu J, Li L, Bai L, Wang Y, Zhang J, Wang H
Molecular and cellular endocrinology 2022 Jun 15;550:111645
Molecular and cellular endocrinology 2022 Jun 15;550:111645
The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM(2.5) exposure-induced pulmonary fibrosis of mice.
Zhang Y, Liu Q, Ning J, Jiang T, Kang A, Li L, Pang Y, Zhang B, Huang X, Wang Q, Bao L, Niu Y, Zhang R
Journal of hazardous materials 2022 Jun 15;432:128655
Journal of hazardous materials 2022 Jun 15;432:128655
Ambient particulate matter exposure plus a high-fat diet exacerbate renal injury by activating the NLRP3 inflammasome and TGF-β1/Smad2 signaling pathway in mice.
Jiang J, Ding S, Zhang G, Dong Y
Ecotoxicology and environmental safety 2022 Jun 15;238:113571
Ecotoxicology and environmental safety 2022 Jun 15;238:113571
GM130 protects against blood-brain barrier disruption and brain injury after intracerebral hemorrhage by regulating autophagy formation.
Deng S, Hu Q, Chen X, Lei Q, Lu W
Experimental gerontology 2022 Jun 15;163:111772
Experimental gerontology 2022 Jun 15;163:111772
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Chen H, Dong L, Chen X, Ding C, Hao M, Peng X, Zhang Y, Zhu H, Liu W
Experimental gerontology 2022 Jun 15;163:111769
Experimental gerontology 2022 Jun 15;163:111769
Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice.
Noda S, Sato S, Fukuda T, Ueno S, Tada N, Hattori N
Molecular brain 2022 Jun 14;15(1):54
Molecular brain 2022 Jun 14;15(1):54
Comparative and mechanistic study of pharmacodynamic difference in anti-breast cancer activity between water and liquor extracts of Xiaojin Pills.
Liu H, Cao B, Li C, Han L, Xu H, Lin J, Zhang D, Xu R
Journal of ethnopharmacology 2022 Jun 12;291:115104
Journal of ethnopharmacology 2022 Jun 12;291:115104
p38α Deficiency in T Cells Ameliorates Diet-Induced Obesity, Insulin Resistance, and Adipose Tissue Senescence.
Meng D, Zhang B, Wang Y, Zheng T, Hu R, Wang B, Otsu K, Wang Y, Huang G
Diabetes 2022 Jun 1;71(6):1205-1217
Diabetes 2022 Jun 1;71(6):1205-1217
A signature of circadian rhythm genes in driving anaplastic thyroid carcinoma malignant progression.
Xu T, Jin T, Lu X, Pan Z, Tan Z, Zheng C, Liu Y, Hu X, Ba L, Ren H, Chen J, Zhu C, Ge M, Huang P
Cellular signalling 2022 Jul;95:110332
Cellular signalling 2022 Jul;95:110332
Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Tang X, Zhang Y, Wang G, Zhang C, Wang F, Shi J, Zhang T, Ding J
Science advances 2022 Jul;8(26):eabn3868
Science advances 2022 Jul;8(26):eabn3868
PPARγ Dysfunction in the Medial Prefrontal Cortex Mediates High-Fat Diet-Induced Depression.
Fu CC, Zhang XY, Xu L, Huang HX, Xu S, Wu QQ, Wang Z, Gu X, Lin LF, Lin S, Fang YY, Cao X, Wang X
Molecular neurobiology 2022 Jul;59(7):4030-4043
Molecular neurobiology 2022 Jul;59(7):4030-4043
NLRP3 inflammasome triggers interleukin-37 release from human monocytes.
Gritsenko A, Díaz-Pino R, López-Castejón G
European journal of immunology 2022 Jul;52(7):1141-1157
European journal of immunology 2022 Jul;52(7):1141-1157
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Huang X, Jiang L, Lu S, Yuan M, Lin H, Li B, Wen Z, Zhong Y
Oncology reports 2022 Jul;48(1)
Oncology reports 2022 Jul;48(1)
Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.
Yuan D, Lin L, Peng Y, Zhou Y, Li L, Xiao W, Gong Z
Journal of food biochemistry 2022 Jul;46(7):e14140
Journal of food biochemistry 2022 Jul;46(7):e14140
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Zheng X, Liu Z, Zhong J, Zhou L, Chen J, Zheng L, Li Z, Zhang R, Pan J, Wu Y, Liu Z, Kang T
Oncogene 2022 Jul;41(28):3587-3598
Oncogene 2022 Jul;41(28):3587-3598
Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain.
Chase R, de la Peña JB, Smith PR, Lawson J, Lou TF, Stanowick AD, Black BJ, Campbell ZT
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22422
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22422
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.
Xie Y, Zou X, Han J, Zhang Z, Feng Z, Ouyang Q, Hua S, Liu Z, Li C, Cai Y, Zou Y, Tang Y, Jiang X
Experimental neurology 2022 Jul;353:114081
Experimental neurology 2022 Jul;353:114081
The α5-nAChR/PD-L1 axis facilitates lung adenocarcinoma cell migration and invasion.
Zhu P, Kang G, Jiao Y, Gui C, Fan H, Li X, Jia Y, Zhang L, Ma X
Human cell 2022 Jul;35(4):1207-1218
Human cell 2022 Jul;35(4):1207-1218
Rapid synthesis of 'yolk-shell'-like nanosystem for MR molecular and chemo-radio sensitization.
Hou M, Zhu K, Hu H, Zheng S, Wu Z, Ren Y, Wu B, Qi L, Wu D, Xu Y, Yan C, Zhao B
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:55-67
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:55-67
Molybdenum and cadmium co-exposure induces endoplasmic reticulum stress-mediated apoptosis by Th1 polarization in Shaoxing duck (Anas platyrhyncha) spleens.
Guo H, Hu R, Huang G, Pu W, Chu X, Xing C, Zhang C
Chemosphere 2022 Jul;298:134275
Chemosphere 2022 Jul;298:134275
Genome-wide transcriptional profiling and functional analysis reveal miR-330-MAPK15 axis involving in cellular responses to deoxynivalenol exposure.
Wang H, Zhou Y, Xu C, Cao Y, Xiao Y, Cai D, Uemoto Y, Wu S, Bao W
Chemosphere 2022 Jul;298:134199
Chemosphere 2022 Jul;298:134199
Melatonin inhibits osteoclastogenesis via RANKL/OPG suppression mediated by Rev-Erbα in osteoblasts.
Tian Y, Ming J
Journal of cellular and molecular medicine 2022 Jul;26(14):4032-4047
Journal of cellular and molecular medicine 2022 Jul;26(14):4032-4047
A racemosin B derivative, C25, suppresses breast cancer growth via lysosomal membrane permeabilization and inhibition of autophagic flux.
Xiao X, Chung PED, Xu M, Hu A, Ju Y, Yang X, Song J, Song J, Wang C, Zacksenhaus E, Liu S, He Z, Ben-David Y
Biochemical pharmacology 2022 Jul;201:115060
Biochemical pharmacology 2022 Jul;201:115060
The BDNF-TrkB signaling pathway in the rostral anterior cingulate cortex is involved in the development of pain aversion in rats with bone cancer via NR2B and ERK-CREB signaling.
Li J, Wang X, Wang H, Wang R, Guo Y, Xu L, Zhang G, Wu J, Wang G
Brain research bulletin 2022 Jul;185:18-27
Brain research bulletin 2022 Jul;185:18-27
Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy.
Liu Y, Wei CH, Li C, Chen WZ, Zhu Y, Xu RS
Neural regeneration research 2022 Jul;17(7):1609-1616
Neural regeneration research 2022 Jul;17(7):1609-1616
Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.
Liu Y, Sun R, Lin X, Wu L, Chen H, Shen S, Li Y, Wei Y, Deng G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113078
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113078
Role of TRPA1/TRPV1 in acute ozone exposure induced murine model of airway inflammation and bronchial hyperresponsiveness.
Li C, Zhang H, Wei L, Liu Q, Xie M, Weng J, Wang X, Chung KF, Adcock IM, Chen Y, Li F
Journal of thoracic disease 2022 Jul;14(7):2698-2711
Journal of thoracic disease 2022 Jul;14(7):2698-2711
ER stress-related protein, CHOP, may serve as a biomarker of mechanical asphyxia: a primary study.
Hu Y, Tian L, Ma K, Han L, Li W, Hu L, Fei G, Zhang T, Yu D, Xu L, Wang F, Xiao B, Chen L
International journal of legal medicine 2022 Jul;136(4):1091-1104
International journal of legal medicine 2022 Jul;136(4):1091-1104
MicroRNA-mediated high expression of PDIA3 was correlated with poor prognosis of patients with LUAD.
Gu X, Li X, Zhang X, Feng R, Zheng M, Liu L, Yang J, Sun H, Zhang Q, Bian T, Zhao H, Liu Y
Genomics 2022 Jul;114(4):110417
Genomics 2022 Jul;114(4):110417
GRSF1 predicts an unfavorable prognosis and promotes tumorigenesis in lung adenocarcinoma based on bioinformatics analysis and in vitro validation.
Huang R, Xu L, Chen Q, Tuersuntuoheti A, Su L, Xu F, Bi Y, Deng Y, Song W, Zhao H, Che X
Annals of translational medicine 2022 Jul;10(13):747
Annals of translational medicine 2022 Jul;10(13):747
Maternal High-Fat Diet Reduces Type-2 Neural Stem Cells and Promotes Premature Neuronal Differentiation during Early Postnatal Development.
Hu X, An J, Ge Q, Sun M, Zhang Z, Cai Z, Tan R, Ma T, Lu H
Nutrients 2022 Jul 8;14(14)
Nutrients 2022 Jul 8;14(14)
Cyclosporin A up-regulated thromboxane A(2) receptor through activation of MAPK and NF-κB pathways in rat mesenteric artery.
Wang C, Han L, Wang T, Wang Y, Liu J, Wang B, Xu CB
European journal of pharmacology 2022 Jul 5;926:175034
European journal of pharmacology 2022 Jul 5;926:175034
Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice.
Liang Q, Xu H, Liu M, Qian L, Yan J, Yang G, Chen L
Journal of the American Heart Association 2022 Jul 5;11(13):e025021
Journal of the American Heart Association 2022 Jul 5;11(13):e025021
Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARγ pathway.
Song CC, Pantopoulos K, Chen GH, Zhong CC, Zhao T, Zhang DG, Luo Z
Cellular and molecular life sciences : CMLS 2022 Jul 4;79(7):394
Cellular and molecular life sciences : CMLS 2022 Jul 4;79(7):394
Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.
Li DM, Wu YX, Hu ZQ, Wang TC, Zhang LL, Zhou Y, Tong X, Xu JY, Qin LQ
Antioxidants (Basel, Switzerland) 2022 Jul 31;11(8)
Antioxidants (Basel, Switzerland) 2022 Jul 31;11(8)
Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice.
Shimizu S, Kasai S, Yamazaki H, Tatara Y, Mimura J, Engler MJ, Tanji K, Nikaido Y, Inoue T, Suganuma H, Wakabayashi K, Itoh K
International journal of molecular sciences 2022 Jul 29;23(15)
International journal of molecular sciences 2022 Jul 29;23(15)
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
Wang P, Liu D, Yan S, Liang Y, Cui J, Guo L, Ren S, Chen P
Toxics 2022 Jul 29;10(8)
Toxics 2022 Jul 29;10(8)
Endoplasmic reticulum stress contributes to cisplatin-induced chronic kidney disease via the PERK-PKCδ pathway.
Shu S, Wang H, Zhu J, Fu Y, Cai J, Chen A, Tang C, Dong Z
Cellular and molecular life sciences : CMLS 2022 Jul 27;79(8):452
Cellular and molecular life sciences : CMLS 2022 Jul 27;79(8):452
MiR-152-5p suppresses osteogenic differentiation of mandible mesenchymal stem cells by regulating ATG14-mediated autophagy.
Li S, Gao L, Zhang W, Yu Y, Zheng J, Liang X, Xin S, Ren W, Zhi K
Stem cell research & therapy 2022 Jul 26;13(1):359
Stem cell research & therapy 2022 Jul 26;13(1):359
miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure.
Qu Q, Liu L, Cui Y, Liu H, Yi J, Bing W, Liu C, Jiang D, Bi Y
Stem cell research & therapy 2022 Jul 26;13(1):352
Stem cell research & therapy 2022 Jul 26;13(1):352
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma.
Huang K, Wang H, Xu J, Xu R, Liu Z, Li Y, Xu Z
Biology 2022 Jul 26;11(8)
Biology 2022 Jul 26;11(8)
Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer.
Liu Y, Wang F, Li Z, Mu Y, Yong VW, Xue M
Biomolecules 2022 Jul 22;12(8)
Biomolecules 2022 Jul 22;12(8)
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Xu Y, Wang X, Han D, Wang J, Luo Z, Jin T, Shi C, Zhou X, Lin L, Shan J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology.
Shao D, Liu X, Wu J, Zhang A, Bai Y, Zhao P, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154177
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154177
ACSL4 promotes colorectal cancer and is a potential therapeutic target of emodin.
Dai G, Wang D, Ma S, Hong S, Ding K, Tan X, Ju W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154149
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154149
Inhibition of TWEAK/Tnfrsf12a axis protects against acute liver failure by suppressing RIPK1-dependent apoptosis.
Li Z, Wang H, Zhu J, Nan N, Lin Y, Zhuang X, Li L, Zhang Y, Huang P
Cell death discovery 2022 Jul 19;8(1):328
Cell death discovery 2022 Jul 19;8(1):328
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Zhong X, Wu Q, Wang Z, Zhang M, Zheng S, Shi F, Chen Y, Che Y, Yuan S, Xing K
Food & function 2022 Jul 18;13(14):7666-7683
Food & function 2022 Jul 18;13(14):7666-7683
Quantitative Proteome Analysis Reveals Melissa officinalis Extract Targets Mitochondrial Respiration in Colon Cancer Cells.
Kuo TT, Lin LC, Chang HY, Chiang PJ, Wu HY, Chen TY, Hsia SM, Huang TC
Molecules (Basel, Switzerland) 2022 Jul 15;27(14)
Molecules (Basel, Switzerland) 2022 Jul 15;27(14)
SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway.
Fang K, Du S, Shen D, Xiong Z, Jiang K, Liang D, Wang J, Xu H, Hu L, Zhai X, Jiang Y, Xia Z, Xie C, Jin D, Cheng W, Meng S, Wang Y
iScience 2022 Jul 15;25(7):104618
iScience 2022 Jul 15;25(7):104618
Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity.
Hayashi Y, Shimizu I, Yoshida Y, Ikegami R, Suda M, Katsuumi G, Fujiki S, Ozaki K, Abe M, Sakimura K, Okuda S, Hayano T, Nakamura K, Walsh K, Jespersen NZ, Nielsen S, Scheele C, Minamino T
iScience 2022 Jul 15;25(7):104547
iScience 2022 Jul 15;25(7):104547
lncRNA SNHG1 regulates odontogenic differentiation of human dental pulp stem cells via miR-328-3p/Wnt/β-catenin pathway.
Fu T, Liu Y, Huang X, Guo Y, Shen J, Shen H
Stem cell research & therapy 2022 Jul 15;13(1):311
Stem cell research & therapy 2022 Jul 15;13(1):311
Procyanidin B2 Alleviates Heat-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
Wang H, Hao W, Yang L, Li T, Zhao C, Yan P, Wei S
International journal of molecular sciences 2022 Jul 14;23(14)
International journal of molecular sciences 2022 Jul 14;23(14)
Metformin protects against pericyte apoptosis and promotes neurogenesis through suppressing JNK p38 MAPK signalling activation in ischemia/reperfusion injury.
Liu C, Zhang D, Lu Z, Man J, Zhang Z, Fu X, Cui K, Wang J
Neuroscience letters 2022 Jul 13;783:136708
Neuroscience letters 2022 Jul 13;783:136708
A novel nitidine chloride nanoparticle overcomes the stemness of CD133(+)EPCAM(+) Huh7 hepatocellular carcinoma cells for liver cancer therapy.
Li D, Zhang Q, Zhou Y, Zhu H, Li T, Du F
BMC pharmacology & toxicology 2022 Jul 12;23(1):48
BMC pharmacology & toxicology 2022 Jul 12;23(1):48
The Capillary Morphogenesis Gene 2 Triggers the Intracellular Hallmarks of Collagen VI-Related Muscular Dystrophy.
Castroflorio E, Pérez Berná AJ, López-Márquez A, Badosa C, Loza-Alvarez P, Roldán M, Jiménez-Mallebrera C
International journal of molecular sciences 2022 Jul 11;23(14)
International journal of molecular sciences 2022 Jul 11;23(14)
The miR-199a-5p/PD-L1 axis regulates cell proliferation, migration and invasion in follicular thyroid carcinoma.
Lin J, Qiu Y, Zheng X, Dai Y, Xu T
BMC cancer 2022 Jul 11;22(1):756
BMC cancer 2022 Jul 11;22(1):756
Selective sphingosine-1-phosphate receptor 1 modulator attenuates blood-brain barrier disruption following traumatic brain injury by inhibiting vesicular transcytosis.
Zhang Y, Wang L, Pan Q, Yang X, Cao Y, Yan J, Wang Y, Tao Y, Fan R, Sun X, Li L
Fluids and barriers of the CNS 2022 Jul 11;19(1):57
Fluids and barriers of the CNS 2022 Jul 11;19(1):57
Cytokine receptor gp130 promotes postnatal proliferation of cardiomyocytes required for the normal functional development of the heart.
Kawagishi H, Nakada T, Numaga-Tomita T, Larrañaga M, Guo A, Song LS, Yamada M
American journal of physiology. Heart and circulatory physiology 2022 Jul 1;323(1):H103-H120
American journal of physiology. Heart and circulatory physiology 2022 Jul 1;323(1):H103-H120
Early-life exposure to bisphenol A induces dysregulation of lipid homeostasis by the upregulation of SCD1 in male mice.
Fang R, Yang S, Gu X, Li C, Bi N, Wang HL
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119201
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119201
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Yu G, Ji S, Yun Y, Cheng K, Zhang H, Jia P, Wang T, Zhang L
Journal of animal science 2022 Jul 1;100(7)
Journal of animal science 2022 Jul 1;100(7)
Genomic polymorphisms at the crhr2 locus improve feed conversion efficiency through alleviation of hypothalamus-pituitary-interrenal axis activity in gibel carp (Carassius gibelio).
Shi C, Lou Q, Fu B, Jin J, Huang J, Lu Y, Jin X, He J, Zhai G, Xie S, Tong J, Gui J, Yin Z
Science China. Life sciences 2022 Jan;65(1):206-214
Science China. Life sciences 2022 Jan;65(1):206-214
MELAS-associated m.5541C>T mutation caused instability of mitochondrial tRNA(Trp) and remarkable mitochondrial dysfunction.
Ji K, Lin Y, Xu X, Wang W, Wang D, Zhang C, Li W, Zhao Y, Yan C
Journal of medical genetics 2022 Jan;59(1):79-87
Journal of medical genetics 2022 Jan;59(1):79-87
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Hao X, Bu W, Lv G, Xu L, Hou D, Wang J, Liu X, Yang T, Zhang X, Liu Q, Gong Y, Shao C
Oncogene 2022 Jan;41(3):427-443
Oncogene 2022 Jan;41(3):427-443
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Li Z, Xu Q, Huangfu N, Chen X, Zhu J
Journal of clinical laboratory analysis 2022 Jan;36(1):e24019
Journal of clinical laboratory analysis 2022 Jan;36(1):e24019
African swine fever virus cysteine protease pS273R inhibits pyroptosis by noncanonically cleaving gasdermin D.
Zhao G, Li T, Liu X, Zhang T, Zhang Z, Kang L, Song J, Zhou S, Chen X, Wang X, Li J, Huang L, Li C, Bu Z, Zheng J, Weng C
The Journal of biological chemistry 2022 Jan;298(1):101480
The Journal of biological chemistry 2022 Jan;298(1):101480
G-alpha interacting protein interacting protein, C terminus 1 regulates epileptogenesis by increasing the expression of metabotropic glutamate receptor 7.
Liu Y, Wang Y, Yang J, Xu T, Tan C, Zhang P, Liu Q, Chen Y
CNS neuroscience & therapeutics 2022 Jan;28(1):126-138
CNS neuroscience & therapeutics 2022 Jan;28(1):126-138
LOXL1-AS1 communicating with TIAR modulates vasculogenic mimicry in glioma via regulation of the miR-374b-5p/MMP14 axis.
Yi B, Li H, Cai H, Lou X, Yu M, Li Z
Journal of cellular and molecular medicine 2022 Jan;26(2):475-490
Journal of cellular and molecular medicine 2022 Jan;26(2):475-490
miR‑30a‑5p induces the adipogenic differentiation of bone marrow mesenchymal stem cells by targeting FAM13A/Wnt/β‑catenin signaling in aplastic anemia.
Wang E, Zhang Y, Ding R, Wang X, Zhang S, Li X
Molecular medicine reports 2022 Jan;25(1)
Molecular medicine reports 2022 Jan;25(1)
The Apolipoprotein C1 is involved in breast cancer progression via EMT and MAPK/JNK pathway.
Zhang H, Wang Y, Liu C, Li W, Zhou F, Wang X, Zheng J
Pathology, research and practice 2022 Jan;229:153746
Pathology, research and practice 2022 Jan;229:153746
Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells.
Oyama T, Ogawa H, Shirai Y, Abe H, Kamiya T, Abe T, Tanuma SI
Biochimie 2022 Jan;192:13-21
Biochimie 2022 Jan;192:13-21
Cyclic helix B peptide promotes random-pattern skin flap survival via TFE3-mediated enhancement of autophagy and reduction of ROS levels.
Lou J, Zhang H, Qi J, Xu Y, Wang X, Jiang J, Hu X, Ni L, Cai Y, Wang X, Gao W, Xiao J, Zhou K
British journal of pharmacology 2022 Jan;179(2):301-321
British journal of pharmacology 2022 Jan;179(2):301-321
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Ma C, Wu H, Yang G, Xiang J, Feng K, Zhang J, Hua Y, Kang L, Fan G, Yang S
British journal of pharmacology 2022 Jan;179(2):252-269
British journal of pharmacology 2022 Jan;179(2):252-269
Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats.
Ren Z, Wang M, Aldhabi M, Zhang R, Liu Y, Liu S, Tang R, Chen Z
Neurobiology of stress 2022 Jan;16:100422
Neurobiology of stress 2022 Jan;16:100422
Irisin lowers blood pressure in Zucker diabetic rats by regulating the functions of renal angiotensin II type 1 receptor via the inhibition of the NF-κB signaling pathway.
Huang Y, Chen Q, Jiang Q, Zhao Z, Fang J, Chen L
Peptides 2022 Jan;147:170688
Peptides 2022 Jan;147:170688
Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway.
Ao L, Gao H, Jia L, Liu S, Guo J, Liu B, Dong Q
Molecular immunology 2022 Jan;141:13-20
Molecular immunology 2022 Jan;141:13-20
The role of KLF4 in melanogenesis and homeostasis in sheep melanocytes.
Qin H, Chen Y, Wang S, Ge S, Pang Q
Acta histochemica 2022 Jan;124(1):151839
Acta histochemica 2022 Jan;124(1):151839
Fe(III)-Shikonin Supramolecular Nanomedicine for Combined Therapy of Tumor via Ferroptosis and Necroptosis.
Feng W, Shi W, Liu S, Liu H, Liu Y, Ge P, Zhang H
Advanced healthcare materials 2022 Jan;11(2):e2101926
Advanced healthcare materials 2022 Jan;11(2):e2101926
Baicalin ameliorates APEC-induced intestinal injury in chicks by inhibiting the PI3K/AKT-mediated NF-κB signaling pathway.
Cheng X, Cao Z, Luo J, Hu R, Cao H, Guo X, Xing C, Yang F, Zhuang Y, Hu G
Poultry science 2022 Jan;101(1):101572
Poultry science 2022 Jan;101(1):101572
Quxie Capsule Alleviates Colitis-associated Colorectal Cancer Through Modulating the Gut Microbiota and Suppressing A. fumigatus-induced Aerobic Glycolysis.
Zhang Z, Chen Y, Zheng Y, Wang L, Shen S, Yang G, Yang Y, Wang T
Integrative cancer therapies 2022 Jan-Dec;21:15347354221138534
Integrative cancer therapies 2022 Jan-Dec;21:15347354221138534
Combined Effects of Tanshinone IIA and an Autophagy Inhibitor on the Apoptosis of Leukemia Cells via p53, Apoptosis-Related Proteins and Oxidative Stress Pathways.
Song YC, Kuo CC, Liu CT, Wu TC, Kuo YT, Yen HR
Integrative cancer therapies 2022 Jan-Dec;21:15347354221117776
Integrative cancer therapies 2022 Jan-Dec;21:15347354221117776
Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis.
Zhang Y, Zhang L, Zheng S, Li M, Xu C, Jia D, Qi Y, Hou T, Wang L, Wang B, Li A, Chen S, Si J, Zhuo W
Gut microbes 2022 Jan-Dec;14(1):2038852
Gut microbes 2022 Jan-Dec;14(1):2038852
REV-ERBs negatively regulate mineralization of the cementoblasts.
Fu L, Wang M, Zhu G, Zhao Z, Sun H, Cao Z, Xia H
Biochemical and biophysical research communications 2022 Jan 8;587:9-15
Biochemical and biophysical research communications 2022 Jan 8;587:9-15
Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis.
Xu P, Hu K, Zhang P, Sun ZG, Zhang N
Cancer cell international 2022 Jan 7;22(1):13
Cancer cell international 2022 Jan 7;22(1):13
Intermittent Fasting Improves High-Fat Diet-Induced Obesity Cardiomyopathy via Alleviating Lipid Deposition and Apoptosis and Decreasing m6A Methylation in the Heart.
Xu Z, Qin Y, Lv B, Tian Z, Zhang B
Nutrients 2022 Jan 7;14(2)
Nutrients 2022 Jan 7;14(2)
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
Yuan Y, Miao Y, Ren T, Huang F, Qian L, Chen X, Zuo Y, Zhang HG, He J, Qiao C, Du Q, Wu Q, Zhang W, Zhu C, Xu Y, Wu D, Shi W, Jiang J, Xu G, Zheng H
EMBO reports 2022 Jan 5;23(1):e53466
EMBO reports 2022 Jan 5;23(1):e53466
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Jin Y, Wang H
Journal of ovarian research 2022 Jan 4;15(1):3
Journal of ovarian research 2022 Jan 4;15(1):3
Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Jiang H, Xu F, Zeng L, Li C, Chen Y, Wang L, Li Z, Liu R
Journal of ethnopharmacology 2022 Jan 30;283:114714
Journal of ethnopharmacology 2022 Jan 30;283:114714
Lycium barbarum polysaccharides attenuates high glucose-induced diabetic retinal angiogenesis by rescuing the expression of miR-15a-5p in RF/6A cells.
Zhu Y, Zhao Q, Jiang Y
Journal of ethnopharmacology 2022 Jan 30;283:114652
Journal of ethnopharmacology 2022 Jan 30;283:114652
Kampo formulas alleviate aging-related emotional disturbances and neuroinflammation in male senescence-accelerated mouse prone 8 mice.
Ito N, Maruko A, Oshima K, Yoshida M, Honma K, Sugiyama C, Nagai T, Kobayashi Y, Odaguchi H, Okada N
Aging 2022 Jan 3;14(1):109-142
Aging 2022 Jan 3;14(1):109-142
DNAJC10 correlates with tumor immune characteristics and predicts the prognosis of glioma patients.
Liu F, Tu Z, Liu J, Long X, Xiao B, Fang H, Huang K, Zhu X
Bioscience reports 2022 Jan 28;42(1)
Bioscience reports 2022 Jan 28;42(1)
iTRAQ-Based Proteomics Analysis of Human Cytomegalovirus Latency and Reactivation in T98G Cells.
Cheng S, Zhao F, Wen L, Yang B, Wang XZ, Huang SN, Jiang X, Zeng WB, Sun JY, Zhang FK, Shen HJ, Fortunato E, Luo MH, Cheng H
Journal of virology 2022 Jan 26;96(2):e0147621
Journal of virology 2022 Jan 26;96(2):e0147621
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Liu W, Ren D, Xiong W, Jin X, Zhu L
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Upregulation of CENPM facilitates lung adenocarcinoma progression via PI3K/AKT/mTOR signaling pathway.
Liu C, Wang Y, Dao Y, Wang S, Hou F, Yang Z, Liu P, Lv J, Lv L, Li G, Zhou Y, Deng Z
Acta biochimica et biophysica Sinica 2022 Jan 25;54(1):99-112
Acta biochimica et biophysica Sinica 2022 Jan 25;54(1):99-112
IKKε protects against starvation-induced NLRP3 inflammasome and pyroptosis in H9c2 cells by alleviating mitochondrial injury.
Chen G, Xu Y, Fan R, Liu Y, Yao Y, Jiang H, Wu Q, Li L, Chen W, Chen X
Biochemical and biophysical research communications 2022 Jan 22;589:267-274
Biochemical and biophysical research communications 2022 Jan 22;589:267-274
BMP7 Functions to Regulate Proliferation of Dermal Papilla Cells in Hu Sheep.
Li Y, Lv X, Wang S, Cao X, Yuan Z, Getachew T, Mwacharo JM, Haile A, Sun W
Genes 2022 Jan 22;13(2)
Genes 2022 Jan 22;13(2)
Single-Base Resolution Mapping Reveals Distinct 5-Formylcytidine in Saccharomyces cerevisiae mRNAs.
Wang Y, Chen Z, Zhang X, Weng X, Deng J, Yang W, Wu F, Han S, Xia C, Zhou Y, Chen Y, Zhou X
ACS chemical biology 2022 Jan 21;17(1):77-84
ACS chemical biology 2022 Jan 21;17(1):77-84
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
Sun S, Gao T, Pang B, Su X, Guo C, Zhang R, Pang Q
Cell death & disease 2022 Jan 21;13(1):73
Cell death & disease 2022 Jan 21;13(1):73
The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease.
Li C, Zheng Y, Liu Y, Jin GH, Pan H, Yin F, Wu J
Aging 2022 Jan 20;14(2):800-810
Aging 2022 Jan 20;14(2):800-810
Bisphenol-A exposure leads to neurotoxicity through upregulating the expression of histone deacetylase 2 in vivo and in vitro.
Bi N, Gu X, Fan A, Li D, Wang M, Zhou R, Sun QC, Wang HL
Toxicology 2022 Jan 15;465:153052
Toxicology 2022 Jan 15;465:153052
Type-III interferon stimulated gene TRIM31 mutation in an HBV patient blocks its ability in promoting HBx degradation.
Xu F, Song H, Xiao Q, Wei Q, Pang X, Gao Y, Tan G
Virus research 2022 Jan 15;308:198650
Virus research 2022 Jan 15;308:198650
Regioselective hydroxylation of carbendazim by mammalian cytochrome P450: A combined experimental and computational study.
Lv X, Li JX, Wang JY, Tian XG, Feng L, Sun CP, Ning J, Wang C, Zhao WY, Li YC, Ma XC
Environmental pollution (Barking, Essex : 1987) 2022 Jan 15;293:118523
Environmental pollution (Barking, Essex : 1987) 2022 Jan 15;293:118523
The role of polypeptide PDTLN1 in suppression of PI3K/AKT signaling causes cardiogenetic disorders in vitro and in vivo.
Yu B, Yao S, Liu L, Li H, Zhu J, Li M, Han S, Yu Z
Life sciences 2022 Jan 15;289:120244
Life sciences 2022 Jan 15;289:120244
Synthesis and structure-activity relationship study of new biaryl amide derivatives and their inhibitory effects against hepatitis C virus.
Liu Y, Li J, Gu Y, Ma L, Cen S, Peng Z, Hu L
European journal of medicinal chemistry 2022 Jan 15;228:114033
European journal of medicinal chemistry 2022 Jan 15;228:114033
Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain.
Rodriguez Ospina S, Blazier DM, Criado-Marrero M, Gould LA, Gebru NT, Beaulieu-Abdelahad D, Wang X, Remily-Wood E, Chaput D, Stevens S, Uversky VN, Bickford PC, Dickey CA, Blair LJ
International journal of molecular sciences 2022 Jan 13;23(2)
International journal of molecular sciences 2022 Jan 13;23(2)
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Qin M, Xin Y, Bian Y, Yang X, Xi T, Xiong J
Cells 2022 Jan 13;11(2)
Cells 2022 Jan 13;11(2)
Short-term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy.
Zhi W, Li S, Wan Y, Wu F, Hong L
Cancer cell international 2022 Jan 11;22(1):18
Cancer cell international 2022 Jan 11;22(1):18
Insight into Shenqi Jiangtang Granule on the improved insulin sensitivity by integrating in silico and in vivo approaches.
Shi S, Sun M, Liu Y, Jiang J, Li F
Journal of ethnopharmacology 2022 Jan 10;282:114672
Journal of ethnopharmacology 2022 Jan 10;282:114672
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
He M, Li L, Wei X, Geng D, Jiang H, Xiangxiang G, Zhang Y, Du H
Journal of ethnopharmacology 2022 Jan 10;282:114580
Journal of ethnopharmacology 2022 Jan 10;282:114580
miR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy.
Zhou Y, Wang C, Ding J, Chen Y, Sun Y, Cheng Z
Cancer cell international 2022 Jan 10;22(1):15
Cancer cell international 2022 Jan 10;22(1):15
Neurokinin-1 receptor promotes non-small cell lung cancer progression through transactivation of EGFR.
Zhang XW, Li L, Hu WQ, Hu MN, Tao Y, Hu H, Miao XK, Yang WL, Zhu Q, Mou LY
Cell death & disease 2022 Jan 10;13(1):41
Cell death & disease 2022 Jan 10;13(1):41
The Role of RAD6B and PEDF in Retinal Degeneration.
Ye Q, Wang J, Liu X, Liu Z, BaZong L, Ma J, Shen R, Ye W, Zhang W, Wang D
Neuroscience 2022 Jan 1;480:19-31
Neuroscience 2022 Jan 1;480:19-31
Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection.
Patil CD, Suryawanshi R, Ames J, Koganti R, Agelidis A, Kapoor D, Yadavalli T, Koujah L, Tseng HC, Shukla D
Journal of immunology (Baltimore, Md. : 1950) 2022 Jan 1;208(1):63-73
Journal of immunology (Baltimore, Md. : 1950) 2022 Jan 1;208(1):63-73
Reassessment of the Proteomic Composition and Function of Extracellular Vesicles in the Seminal Plasma.
Wang H, Zhu Y, Tang C, Zhou Z, Wang Z, Li Z, Zheng X, Chen S, Zhou Y, Liang A, Li Y, Lin Y, Sun F
Endocrinology 2022 Jan 1;163(1)
Endocrinology 2022 Jan 1;163(1)
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Huang L, Han Y, Zhou Q, Sun Z, Yan J
Translational neuroscience 2022 Jan 1;13(1):301-308
Translational neuroscience 2022 Jan 1;13(1):301-308
Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
Fan JH, Xu MM, Zhou LM, Gui ZW, Huang L, Li XG, Ye XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153881
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153881
Novel variant in BRAT1 with the lethal neonatal rigidity and multifocal seizure syndrome.
Li W, Wu S, Xu H, Zhao X, Pan Y, Huang H, Lv H, Zhu X, Liu Y
Pediatric research 2022 Feb;91(3):565-571
Pediatric research 2022 Feb;91(3):565-571
Extracellular domain of semaphorin 5A serves a tumor‑suppressing role by activating interferon signaling pathways in lung adenocarcinoma cells.
Chen MZ, Su LY, Ko PH, Hsu MH, Chuang LL, Chen LH, Lu TP, Chuang EY, Chow LP, Tsai MH, Hsu HH, Lai LC
International journal of oncology 2022 Feb;60(2)
International journal of oncology 2022 Feb;60(2)
The Role of Ferroptosis Signature in Overall Survival and Chemotherapy of Pancreatic Adenocarcinoma.
Wei W, Hu Q, Li W, Li M, Dong S, Peng Y, Yin J, Lu Y, Liu L, Zhao Q
DNA and cell biology 2022 Feb;41(2):116-127
DNA and cell biology 2022 Feb;41(2):116-127
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Ayesha M, Majid A, Zhao D, Greenaway FT, Yan N, Liu Q, Liu S, Sun MZ
Journal of advanced research 2022 Feb;36:147-161
Journal of advanced research 2022 Feb;36:147-161
MiR-195 promotes pancreatic β-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.
Xu Y, Tang Z, Dai H, Hou J, Li F, Tang Z, Zhang D
Obesity (Silver Spring, Md.) 2022 Feb;30(2):447-459
Obesity (Silver Spring, Md.) 2022 Feb;30(2):447-459
Tumor necrosis factor α upregulates the bile acid efflux transporter OATP3A1 via multiple signaling pathways in cholestasis.
Li M, Wang W, Cheng Y, Zhang X, Zhao N, Tan Y, Xie Q, Chai J, Pan Q
The Journal of biological chemistry 2022 Feb;298(2):101543
The Journal of biological chemistry 2022 Feb;298(2):101543
RNA-binding protein RBM28 can translocate from the nucleolus to the nucleoplasm to inhibit the transcriptional activity of p53.
Lin X, Zhou L, Zhong J, Zhong L, Zhang R, Kang T, Wu Y
The Journal of biological chemistry 2022 Feb;298(2):101524
The Journal of biological chemistry 2022 Feb;298(2):101524
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)
Molecular medicine reports 2022 Feb;25(2)
Extracellular matrix stiffness controls VEGF(165) secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis.
Bao M, Chen Y, Liu JT, Bao H, Wang WB, Qi YX, Lv F
Angiogenesis 2022 Feb;25(1):71-86
Angiogenesis 2022 Feb;25(1):71-86
Immune-related gene expression in skin, inflamed and keloid tissue from patients with keloids.
Shan M, Liu H, Song K, Liu S, Hao Y, Wang Y
Oncology letters 2022 Feb;23(2):72
Oncology letters 2022 Feb;23(2):72
Altered transsulfuration pathway enzymes and redox homeostasis in inherited retinal degenerative diseases.
Badiei A, Beltran WA, Aguirre GD
Experimental eye research 2022 Feb;215:108902
Experimental eye research 2022 Feb;215:108902
PI3K/Akt Signaling Pathway Ameliorates Oxidative Stress-Induced Apoptosis upon Manganese Exposure in PC12 Cells.
Tan Y, Cheng H, Su C, Chen P, Yang X
Biological trace element research 2022 Feb;200(2):749-760
Biological trace element research 2022 Feb;200(2):749-760
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Mu J, Que Y, Li X, Zhou F, Jin L, Li S, Zhu C
Vascular pharmacology 2022 Feb;142:106941
Vascular pharmacology 2022 Feb;142:106941
Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.
Pei Y, Cheng F, Li W, Yu Q, Ma C, Zou Y, Xu T, Liu S, Zhang S, Wang Q
Journal of bioscience and bioengineering 2022 Feb;133(2):146-154
Journal of bioscience and bioengineering 2022 Feb;133(2):146-154
Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice.
Song H, Zhang X, Zhai R, Liang H, Song G, Yuan Y, Xu Y, Yan Y, Qiu L, Sun T
Bioengineered 2022 Feb;13(2):4598-4609
Bioengineered 2022 Feb;13(2):4598-4609
Bone marrow mesenchymal stem cells-derived exosomal microRNA-124-3p attenuates hypoxic-ischemic brain damage through depressing tumor necrosis factor receptor associated factor 6 in newborn rats.
Min W, Wu Y, Fang Y, Hong B, Dai D, Zhou Y, Liu J, Li Q
Bioengineered 2022 Feb;13(2):3194-3206
Bioengineered 2022 Feb;13(2):3194-3206
tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).
Zhang Z, Liu Z, Zhao W, Zhao X, Tao Y
Bioengineered 2022 Feb;13(2):2087-2098
Bioengineered 2022 Feb;13(2):2087-2098
Protective effects of agrimonolide on hypoxia-induced H9c2 cell injury by maintaining mitochondrial homeostasis.
Wang C, Qi C, Liu M, Wang L, Cheng G, Li L, Xing Y, Zhao X, Liu J
Journal of cellular biochemistry 2022 Feb;123(2):306-321
Journal of cellular biochemistry 2022 Feb;123(2):306-321
Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.
Liao W, Xu N, Zhang H, Liao W, Wang Y, Wang S, Zhang S, Jiang Y, Xie W, Zhang Y
Clinical and translational medicine 2022 Feb;12(2):e699
Clinical and translational medicine 2022 Feb;12(2):e699
Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis.
Li XY, Wang DP, Li S, Xue WH, Qian XH, Liu KL, Li YH, Lin QQ, Dong G, Meng FH, Jian LY
Bioorganic chemistry 2022 Feb;119:105469
Bioorganic chemistry 2022 Feb;119:105469
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Guo D, Yin TL, Wang SJ, Yang J
Placenta 2022 Feb;118:20-31
Placenta 2022 Feb;118:20-31
Resveratrol attenuates inflammation and apoptosis through alleviating endoplasmic reticulum stress via Akt/mTOR pathway in fungus-induced allergic airways inflammation.
Wang S, Gong L, Mo Y, Zhang J, Jiang Z, Tian Z, Shao C
International immunopharmacology 2022 Feb;103:108489
International immunopharmacology 2022 Feb;103:108489
Resveratrol regulates intestinal barrier function in cyclophosphamide-induced immunosuppressed mice.
Song X, Liu L, Peng S, Liu T, Chen Y, Jia R, Zou Y, Li L, Zhao X, Liang X, Tang H, Yin Z
Journal of the science of food and agriculture 2022 Feb;102(3):1205-1215
Journal of the science of food and agriculture 2022 Feb;102(3):1205-1215
Phycocyanin inhibits Helicobacter pylori-induced hyper-proliferation in AGS cells via activation of the ROS/MAPK signaling pathway.
Bi Y, Wu D, Wu X, Wang F, Yu H, Liu P, Cui G, Chen Z
Annals of translational medicine 2022 Feb;10(4):176
Annals of translational medicine 2022 Feb;10(4):176
CPNE1 is a potential prognostic biomarker, associated with immune infiltrates and promotes progression of hepatocellular carcinoma.
Su J, Huang Y, Wang Y, Li R, Deng W, Zhang H, Xiong H
Cancer cell international 2022 Feb 9;22(1):67
Cancer cell international 2022 Feb 9;22(1):67
Therapeutic effect of adipose stromal vascular fraction spheroids for partial bladder outlet obstruction induced underactive bladder.
Liu J, Zhou L, Zhao F, Zhou C, Yang T, Xu Z, Wang X, Xu L, Xu Z, Ge Y, Wu R, Jia R
Stem cell research & therapy 2022 Feb 9;13(1):68
Stem cell research & therapy 2022 Feb 9;13(1):68
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Tang H, Li J, Zhou Q, Li S, Xie C, Niu L, Ma J, Li C
Cell death discovery 2022 Feb 8;8(1):54
Cell death discovery 2022 Feb 8;8(1):54
Treatment of bladder cancer by geoinspired synthetic chrysotile nanocarrier-delivered circPRMT5 siRNA.
Yu C, Zhang Y, Wang N, Wei W, Cao K, Zhang Q, Ma P, Xie D, Wu P, Liu B, Liu J, Xiang W, Hu X, Liu X, Xie J, Tang J, Long Z, Wang L, Zeng H, Liu J
Biomaterials research 2022 Feb 5;26(1):6
Biomaterials research 2022 Feb 5;26(1):6
CTRP3 alleviates cardiac ischemia/reperfusion injury via LAMP1/JIP2/JNK signaling pathway.
Song Y, Zhang Y, Wan Z, Pan J, Gao F, Li F, Zhou J, Chen J
Aging 2022 Feb 3;14(3):1321-1335
Aging 2022 Feb 3;14(3):1321-1335
Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound.
Roy R, Zayas J, Singh SK, Delgado K, Wood SJ, Mohamed MF, Frausto DM, Albalawi YA, Price TP, Estupinian R, Giurini EF, Kuzel TM, Zloza A, Reiser J, Shafikhani SH
eLife 2022 Feb 3;11
eLife 2022 Feb 3;11
Deregulated expression and subcellular localization of CPSF6, a circRNA-binding protein, promote malignant development of esophageal squamous cell carcinoma.
Guo S, Wang G, Zhao Z, Li D, Song Y, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2022 Feb 28;34(1):11-27
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2022 Feb 28;34(1):11-27
Tamoxifen Exerts Anticancer Effects on Pituitary Adenoma Progression via Inducing Cell Apoptosis and Inhibiting Cell Migration.
Lv T, Zhang Z, Yu H, Ren S, Wang J, Li S, Sun L
International journal of molecular sciences 2022 Feb 28;23(5)
International journal of molecular sciences 2022 Feb 28;23(5)
Dietary selenium sources differentially regulate selenium concentration, mRNA and protein expression of representative selenoproteins in various tissues of yellow catfish Pelteobagrus fulvidraco.
Xu XJ, Zhang DG, Zhao T, Xu YH, Luo Z
The British journal of nutrition 2022 Feb 28;127(4):490-502
The British journal of nutrition 2022 Feb 28;127(4):490-502
TJ-M2010-5, A self-developed MyD88 inhibitor, attenuates liver fibrosis by inhibiting the NF-κB pathway.
Xie Y, Du D, Zhang L, Yang Y, Zou Z, Li Z, Zhou L, Shang R, Zhou P
Chemico-biological interactions 2022 Feb 25;354:109839
Chemico-biological interactions 2022 Feb 25;354:109839
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.
Liang L, Liu L, Zhou W, Yang C, Mai G, Li H, Chen Y
Clinical science (London, England : 1979) 2022 Feb 25;136(4):291-307
Clinical science (London, England : 1979) 2022 Feb 25;136(4):291-307
Gata3 Silencing Is Involved in Neuronal Differentiation and Its Abnormal Expression Impedes Neural Activity in Adult Retinal Neurocytes.
Chen P, Wu Y, Zhuang J, Liu X, Luo Q, Wang Q, Jiang Z, He A, Chen S, Chen X, Qiu J, Li Y, Yang Y, Yu K, Zhuang J
International journal of molecular sciences 2022 Feb 24;23(5)
International journal of molecular sciences 2022 Feb 24;23(5)
Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.
Zuo L, Zhu Y, Han J, Liu H
Aging 2022 Feb 24;14(4):1891-1909
Aging 2022 Feb 24;14(4):1891-1909
Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner.
Zhuang J, Cheng G, Huang J, Guo H, Lai Y, Wang J, Shan Z, Zheng S
BMC cardiovascular disorders 2022 Feb 23;22(1):69
BMC cardiovascular disorders 2022 Feb 23;22(1):69
Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer.
Sheng W, Tang J, Cao R, Shi X, Ma Y, Dong M
Cell death & disease 2022 Feb 23;13(2):173
Cell death & disease 2022 Feb 23;13(2):173
Overexpressed integrin alpha 2 inhibits the activation of the transforming growth factor β pathway in pancreatic cancer via the TFCP2-SMAD2 axis.
Cai H, Guo F, Wen S, Jin X, Wu H, Ren D
Journal of experimental & clinical cancer research : CR 2022 Feb 22;41(1):73
Journal of experimental & clinical cancer research : CR 2022 Feb 22;41(1):73
Curcumin alleviates hepatic steatosis by improving mitochondrial function in postnatal overfed rats and fatty L02 cells through the SIRT3 pathway.
Du S, Zhu X, Zhou N, Zheng W, Zhou W, Li X
Food & function 2022 Feb 21;13(4):2155-2171
Food & function 2022 Feb 21;13(4):2155-2171
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Wang N, Feng BN, Hu B, Cheng YL, Guo YH, Qian H
Food & function 2022 Feb 21;13(4):2019-2032
Food & function 2022 Feb 21;13(4):2019-2032
Blocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization.
Liu H, Zhao D, Li H, Zhang W, Lin Q, Wang X, Zheng S, Zhang L, Li L, Hu S, Hu Y
Cell death & disease 2022 Feb 21;13(2):166
Cell death & disease 2022 Feb 21;13(2):166
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway.
Chen GH, Song CC, Pantopoulos K, Wei XL, Zheng H, Luo Z
Free radical biology & medicine 2022 Feb 20;180:95-107
Free radical biology & medicine 2022 Feb 20;180:95-107
METTL3-m(6)A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Peng Z, Gong Y, Wang X, He W, Wu L, Zhang L, Xiong L, Huang Y, Su L, Shi P, Cao X, Liu R, Li Y, Xiao H
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Feb 2;30(2):932-946
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Feb 2;30(2):932-946
Nanog mediated by FAO/ACLY signaling induces cellular dormancy in colorectal cancer cells.
Zhang M, Peng R, Wang H, Yang Z, Zhang H, Zhang Y, Wang M, Wang H, Lin J, Zhao Q, Liu J
Cell death & disease 2022 Feb 17;13(2):159
Cell death & disease 2022 Feb 17;13(2):159
Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice.
Zhang M, Zhong H, Cao T, Huang Y, Ji X, Fan GC, Peng T
International journal of molecular sciences 2022 Feb 16;23(4)
International journal of molecular sciences 2022 Feb 16;23(4)
Integrated single-cell multiomics analysis reveals novel candidate markers for prognosis in human pancreatic ductal adenocarcinoma.
Fan X, Lu P, Wang H, Bian S, Wu X, Zhang Y, Liu Y, Fu D, Wen L, Hao J, Tang F
Cell discovery 2022 Feb 15;8(1):13
Cell discovery 2022 Feb 15;8(1):13
Mitochondria-Dependent Oxidative Stress Mediates ZnO Nanoparticle (ZnO NP)-Induced Mitophagy and Lipotoxicity in Freshwater Teleost Fish.
Chen GH, Song CC, Zhao T, Hogstrand C, Wei XL, Lv WH, Song YF, Luo Z
Environmental science & technology 2022 Feb 15;56(4):2407-2420
Environmental science & technology 2022 Feb 15;56(4):2407-2420
A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins.
Mu M, Yu Q, Zhang Q, Guo J, Wang X, Sun X, Yu J
Cancer cell international 2022 Feb 14;22(1):80
Cancer cell international 2022 Feb 14;22(1):80
Chicoric Acid Prevents Neuroinflammation and Neurodegeneration in a Mouse Parkinson's Disease Model: Immune Response and Transcriptome Profile of the Spleen and Colon.
Wang N, Li R, Feng B, Cheng Y, Guo Y, Qian H
International journal of molecular sciences 2022 Feb 12;23(4)
International journal of molecular sciences 2022 Feb 12;23(4)
Design, Synthesis, and Biological Evaluation of 2-((4-Bisarylmethyl-piperazin-1-yl)methyl)benzonitrile Derivatives as HCV Entry Inhibitors.
Wang Y, Li J, Tan J, Yang B, Quan Y, Peng Z, Li Y, Li Z
Journal of medicinal chemistry 2022 Feb 10;65(3):2107-2121
Journal of medicinal chemistry 2022 Feb 10;65(3):2107-2121
RNA-seq Analysis Reveals Potential Molecular Mechanisms of ZNF580/ZFP580 Promoting Neuronal Survival and Inhibiting Apoptosis after Hypoxic-ischemic Brain damage.
Yin C, Ji Y, Ma N, Chen K, Zhang W, Bai D, Jia X, Xia S, Yin H
Neuroscience 2022 Feb 10;483:52-65
Neuroscience 2022 Feb 10;483:52-65
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
Xu T, Wang X, Ma C, Ji J, Xu W, Shao Q, Liao X, Li Y, Cheng F, Wang Q
Journal of ethnopharmacology 2022 Feb 10;284:114773
Journal of ethnopharmacology 2022 Feb 10;284:114773
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study.
Wang J, Wang B, Zhou B, Chen J, Qi J, Shi L, Yu S, Chen G, Kang M, Jin X, Wang L, Xu J, Zhu L, Chen J
Cancer cell international 2022 Feb 10;22(1):69
Cancer cell international 2022 Feb 10;22(1):69
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
Zhang X, Li T, Yang M, Du Q, Wang R, Fu B, Tan Y, Cao M, Chen Y, Wang Q, Hu R
Cell death & disease 2022 Feb 10;13(2):138
Cell death & disease 2022 Feb 10;13(2):138
Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).
Xu YC, Liu GH, Xu YH, Zhao T, Zheng H, Tan XY
The Science of the total environment 2022 Feb 1;806(Pt 3):151290
The Science of the total environment 2022 Feb 1;806(Pt 3):151290
Cytokine Profile From the Ligamentum Flavum in Patients with Ossification of the Posterior Longitudinal Ligament in the Cervical Spine.
Yayama T, Mori K, Saito H, Fujikawa H, Kitagawa M, Okumura N, Nishizawa K, Nakamura A, Kumagai K, Mimura T, Imai S
Spine 2022 Feb 1;47(3):277-285
Spine 2022 Feb 1;47(3):277-285
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Han QJ, Han G, Peng J, Tang Z
Free radical biology & medicine 2022 Feb 1;179:416-417
Free radical biology & medicine 2022 Feb 1;179:416-417
Tetrahydroxy stilbene glycoside attenuates endothelial cell premature senescence induced by H(2)O(2) through the microRNA-34a/SIRT1 pathway.
Zhang L, Guo Y, Shi S, Zhuge Y, Chen N, Ding Z, Jin B
Scientific reports 2022 Feb 1;12(1):1708
Scientific reports 2022 Feb 1;12(1):1708
Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.
Kong L, Zhang W, Liu S, Zhong Z, Zheng G
Plant foods for human nutrition (Dordrecht, Netherlands) 2022 Dec;77(4):529-537
Plant foods for human nutrition (Dordrecht, Netherlands) 2022 Dec;77(4):529-537
miR-550a-5p promotes the proliferation and migration of hepatocellular carcinoma by targeting GNE via the Wnt/β-catenin signaling pathway.
Li CM, Wu W, Zhu Z, Lu PL, Gong JP, Ma R
Neoplasma 2022 Dec;69(6):1359-1372
Neoplasma 2022 Dec;69(6):1359-1372
DNA2 mutation causing multisystemic disorder with impaired mitochondrial DNA maintenance.
Sun J, Su W, Deng J, Qin Y, Wang Z, Liu Y
Journal of human genetics 2022 Dec;67(12):691-699
Journal of human genetics 2022 Dec;67(12):691-699
Qushi Huayu decoction attenuated hepatic lipid accumulation via JAK2/STAT3/CPT-1A-related fatty acid β-oxidation in mice with non-alcoholic steatohepatitis.
Sun Q, Wang X, Xin X, An Z, Hu Y, Feng Q
Pharmaceutical biology 2022 Dec;60(1):2124-2133
Pharmaceutical biology 2022 Dec;60(1):2124-2133
Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.
Tian J, Wang XL, Wang LC, Chen F, Tian Y, Ma L, Pan CY, Wang YP
Pharmaceutical biology 2022 Dec;60(1):1331-1340
Pharmaceutical biology 2022 Dec;60(1):1331-1340
Nanoparticle endothelial delivery of PGC-1α attenuates hypoxia-induced pulmonary hypertension by attenuating EndoMT-caused vascular wall remodeling.
Cai D, Chen SY
Redox biology 2022 Dec;58:102524
Redox biology 2022 Dec;58:102524
CCK regulates osteogenic differentiation through TNFα/NF-κB in peri-implantitis.
Chou L, Chang Y, Lan K, Liu M, Lu Y, Li X, Li P, Xu Y
The Journal of international medical research 2022 Dec;50(12):3000605221141312
The Journal of international medical research 2022 Dec;50(12):3000605221141312
Mahonia Alkaloids (MA) Ameliorate Depression Induced Gap Junction Dysfunction by miR-205/Cx43 Axis.
He J, Li D, Wei J, Wang S, Chu S, Zhang Z, He F, Wei D, Li Y, Xie J, Lai K, Chen N, Wei G
Neurochemical research 2022 Dec;47(12):3761-3776
Neurochemical research 2022 Dec;47(12):3761-3776
HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks.
Lu L, Jin C, Dong PF, Wang ZY
Veterinary research communications 2022 Dec;46(4):1023-1032
Veterinary research communications 2022 Dec;46(4):1023-1032
Ethanolic extract of root from Arctium lappa L ameliorates obesity and hepatic steatosis in rats by regulating the AMPK/ACC/CPT-1 pathway.
Ma K, Sheng W, Gao R, Feng J, Huang W, Cui L, Liu J, Li Y
Journal of food biochemistry 2022 Dec;46(12):e14455
Journal of food biochemistry 2022 Dec;46(12):e14455
ITGA2 induces STING expression in pancreatic cancer by inducing DNMT1 degradation.
Meng J, Cai H, Sun Y, Wen S, Wu H, Ren D
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1421-1434
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1421-1434
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Zhang Q, Gao Y, Zhang Y, Jing M, Wang D, Wang Y, Khattak S, Qi H, Cai C, Zhang J, Ngowi EE, Khan NH, Li T, Ji A, Jiang Q, Ji X, Li Y, Wu D
Oncogene 2022 Dec;41(49):5238-5252
Oncogene 2022 Dec;41(49):5238-5252
Involvement of LARP7 in Activation of SIRT1 to Inhibit NF-κB Signaling Protects Microglia from Acrylamide-Induced Neuroinflammation.
Guo J, Xue H, Zhong H, Sun W, Zhao S, Meng J, Jiang P
Neurotoxicity research 2022 Dec;40(6):2016-2026
Neurotoxicity research 2022 Dec;40(6):2016-2026
circRNA-MSR regulates the expression of FBXO21 to inhibit chondrocyte autophagy by targeting miR-761 in osteoarthritis.
Jia Z, Liu J, Wang J
The Kaohsiung journal of medical sciences 2022 Dec;38(12):1168-1177
The Kaohsiung journal of medical sciences 2022 Dec;38(12):1168-1177
Cyclophilin A binds to AKT1 and facilitates the tumorigenicity of Epstein-Barr virus by mediating the activation of AKT/mTOR/NF-κB positive feedback loop.
Xin S, Liu L, Li Y, Yang J, Zuo L, Cao P, Yan Q, Li S, Yang L, Cui T, Lu J
Virologica Sinica 2022 Dec;37(6):913-921
Virologica Sinica 2022 Dec;37(6):913-921
A novel IFNbeta-induced long non-coding RNA ZAP-IT1 interrupts Zika virus replication in A549 cells.
Huang Y, Su Y, Shen L, Huo Z, Chen C, Sun T, Tian X, Li N, Yang C
Virologica Sinica 2022 Dec;37(6):904-912
Virologica Sinica 2022 Dec;37(6):904-912
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Gao Y, Zheng X, Chang B, Lin Y, Huang X, Wang W, Ding S, Zhan W, Wang S, Xiao B, Huo L, Yu Y, Chen Y, Gong R, Wu Y, Zhang R, Zhong L, Wang X, Chen Q, Gao S, Jiang Z, Wei D, Kang T
Cell research 2022 Dec;32(12):1086-1104
Cell research 2022 Dec;32(12):1086-1104
miR-1275 Inhibits Human Omental Adipose-Derived Stem Cells Differentiation Toward the Beige Phenotype via PRDM16.
Lin C, He X, Chen X, Liu L, Guan H, Xiao H, Li Y
Stem cells and development 2022 Dec;31(23-24):799-809
Stem cells and development 2022 Dec;31(23-24):799-809
Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy.
Li J, Chen M, Lu L, Wang J, Tan L
Respiratory physiology & neurobiology 2022 Dec;306:103961
Respiratory physiology & neurobiology 2022 Dec;306:103961
Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation.
Espinoza MF, Nguyen KK, Sycks MM, Lyu Z, Quanrud GM, Montoya MR, Genereux JC
The Journal of biological chemistry 2022 Dec;298(12):102597
The Journal of biological chemistry 2022 Dec;298(12):102597
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Xie W, Guo D, Li J, Yue L, Kang Q, Chen G, Zhou T, Wang H, Zhuang K, Leng L, Li H, Chen Z, Gao W, Zhang J
Cell death and differentiation 2022 Dec;29(12):2417-2428
Cell death and differentiation 2022 Dec;29(12):2417-2428
Salivary non-apoptotic tumoral microvesicles: A potential progressive marker in oral cancer patients.
Man QW, Li RF, Bu LL, Zhao Y, Liu B
Journal of cellular and molecular medicine 2022 Dec;26(24):5955-5965
Journal of cellular and molecular medicine 2022 Dec;26(24):5955-5965
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
Glucocorticoid Receptor Contributes to Electroacupuncture-Induced Analgesia by Inhibiting Nav1.7 Expression in Rats With Inflammatory Pain Induced by Complete Freund's Adjuvant.
Luo H, Zhang Y, Zhang J, Shao J, Ren X, Zang W, Cao J, Xu B
Neuromodulation : journal of the International Neuromodulation Society 2022 Dec;25(8):1393-1402
Neuromodulation : journal of the International Neuromodulation Society 2022 Dec;25(8):1393-1402
Therapeutic effects of JLX001 on neuronal necroptosis after cerebral ischemia-reperfusion in rats.
Li W, Gou X, Xu D, Zhou L, Li F, Ye A, Hu Y, Li Y
Experimental brain research 2022 Dec;240(12):3167-3182
Experimental brain research 2022 Dec;240(12):3167-3182
Inhibition of protein disulfide isomerase with PACMA-31 regulates monocyte tissue factor through transcriptional and posttranscriptional mechanisms.
Beckmann L, Mäder J, Voigtlaender M, Klingler F, Schulenkorf A, Lehr C, Regenhardt J, Bokemeyer C, Ruf W, Rolling C, Langer F
Thrombosis research 2022 Dec;220:48-59
Thrombosis research 2022 Dec;220:48-59
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
Zheng Q, Liu M, Fu J
Reproductive biology 2022 Dec;22(4):100706
Reproductive biology 2022 Dec;22(4):100706
Study on the correlation of high expression level of HuD with seborrheic keratosis and skin aging.
Chen J, Liu J, Wang Z, Xu J, Tao J, Li H
Journal of cosmetic dermatology 2022 Dec;21(12):7043-7049
Journal of cosmetic dermatology 2022 Dec;21(12):7043-7049
Spermidine Alleviates Intrauterine Hypoxia-Induced Offspring Newborn Myocardial Mitochondrial Damage in Rats by Inhibiting Oxidative Stress and Regulating Mitochondrial Quality Control.
Chai N, Zheng H, Zhang H, Li L, Yu X, Wang L, Bi X, Yang L, Niu T, Liu X, Zhao Y, Dong L
Iranian journal of pharmaceutical research : IJPR 2022 Dec;21(1):e133776
Iranian journal of pharmaceutical research : IJPR 2022 Dec;21(1):e133776
Putative targeting by BX795 causes decrease in protein kinase C protein levels and inhibition of HSV1 infection.
Suryawanshi RK, Patil CD, Wu D, Panda PK, Singh SK, Volety I, Ahuja R, Mishra YK, Shukla D
Antiviral research 2022 Dec;208:105454
Antiviral research 2022 Dec;208:105454
Necrosulfonamide ameliorates intestinal inflammation via inhibiting GSDMD-medicated pyroptosis and MLKL-mediated necroptosis.
Yang W, Tao K, Wang Y, Huang Y, Duan C, Wang T, Li C, Zhang P, Yin Y, Gao J, Li R
Biochemical pharmacology 2022 Dec;206:115338
Biochemical pharmacology 2022 Dec;206:115338
Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction.
Butterworth S, Torelli F, Lockyer EJ, Wagener J, Song OR, Broncel M, Russell MRG, Moreira-Souza ACA, Young JC, Treeck M
PLoS pathogens 2022 Dec;18(12):e1011021
PLoS pathogens 2022 Dec;18(12):e1011021
Polysaccharide ORP-1 isolated from Oudemansiella raphanipes ameliorates age-associated intestinal epithelial barrier dysfunction in Caco-2 cells monolayer.
Pan WJ, Shi LL, Ren YR, Yao CY, Lu YM, Chen Y
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112038
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112038
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744
Nutrition research and practice 2022 Dec;16(6):729-744
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Liu L, Li X, Bu W, Jin N, Meng Y, Wang Y, Wang D, Xu X, Zhou D, Sun H
Materials today. Bio 2022 Dec;16:100344
Materials today. Bio 2022 Dec;16:100344
Hepatic inhibitors expression profiling of venom-challenged Sinonatrix annularis and antidotal activities.
Lian Q, Zhong L, Fu K, Ji Y, Zhang X, Liu C, Huang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113900
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113900
Notum leads to potential pro-survival of OSCC through crosstalk between Shh and Wnt/β-catenin signaling via p-GSK3β.
Yang P, Li C, Zhou Q, Zhang X, Kou Y, Feng Q, Wang H, Su R, Hasegawa T, Liu H, Li M
The international journal of biochemistry & cell biology 2022 Dec;153:106316
The international journal of biochemistry & cell biology 2022 Dec;153:106316
Extracellular trap can be trained as a memory response.
Gao Y, Zhang JG, Liu ZZ, Ma K, Lin XQ, Zhang JB, Chen W, Yang YJ
Virulence 2022 Dec;13(1):471-482
Virulence 2022 Dec;13(1):471-482
Prokineticin 2 promotes macrophages-mediated antibacterial host defense against bacterial pneumonia.
Tu Q, Yu X, Xie W, Luo Y, Tang H, Chen K, Ruan Y, Li Y, Zhou J, Yin Y, Chen D, Song Z
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Dec;125:103-113
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Dec;125:103-113
Candida tropicalis induces NLRP3 inflammasome activation via glycogen metabolism-dependent glycolysis and JAK-STAT1 signaling pathway in myeloid-derived suppressor cells to promote colorectal carcinogenesis.
Zhang Z, Chen Y, Yin Y, Chen Y, Chen Q, Bing Z, Zheng Y, Hou Y, Shen S, Chen Y, Wang T
International immunopharmacology 2022 Dec;113(Pt B):109430
International immunopharmacology 2022 Dec;113(Pt B):109430
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Cai W, Zhang Y, Jin W, Wei S, Chen J, Zhong C, Zhong Y, Tu C, Peng H
International immunopharmacology 2022 Dec;113(Pt A):109336
International immunopharmacology 2022 Dec;113(Pt A):109336
MAC mediates mammary duct epithelial cell injury in plasma cell mastitis and granulomatous mastitis.
Zhang HJ, Ding PP, Zhang XS, Wang XC, Sun DW, Bu QA, Li XQ
International immunopharmacology 2022 Dec;113(Pt A):109303
International immunopharmacology 2022 Dec;113(Pt A):109303
SPRY4 promotes adipogenic differentiation of human mesenchymal stem cells through the MEK-ERK1/2 signaling pathway.
Li N, Chen Y, Wang H, Li J, Zhao RC
Adipocyte 2022 Dec;11(1):588-600
Adipocyte 2022 Dec;11(1):588-600
Bioinformatics analysis to obtain critical genes regulated in subcutaneous adipose tissue after bariatric surgery.
Chen S, Jiang Y, Qi X, Song P, Tang L, Liu H
Adipocyte 2022 Dec;11(1):550-561
Adipocyte 2022 Dec;11(1):550-561
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Wang H, Yao J, Chen Y, Wang Y, Liu Y, Liao Y, Liang Z, Dong YH, Qu M, Ge X, Zhou X
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Mdivi-1 improves postoperative neurocognitive disorders in aged rats undergoing splenectomy by inhibiting dynamin-related protein-1.
Lin N, Jin JW, Lai ZM, Zhang DF, Chen Y, Guo HG, Liu JL
Annals of translational medicine 2022 Dec;10(24):1338
Annals of translational medicine 2022 Dec;10(24):1338
Heat shock protein 40 of Streptococcus pneumoniae induces immune response of human dendritic cells via TLR4-dependent p38 MAPK and JNK signaling pathways.
Liu JJ, Lin JC, Chen LN
Immunity, inflammation and disease 2022 Dec;10(12):e735
Immunity, inflammation and disease 2022 Dec;10(12):e735
Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation.
Zhou Y, Yang JJ, Cheng Y, Feng GX, Yang RH, Yuan Y, Wang LY, Wang M, Kong L
Cells 2022 Dec 9;11(24)
Cells 2022 Dec 9;11(24)
Molecular profiling identifies distinct subtypes across TP53 mutant tumors.
Chen X, Liu T, Wu J, Zhu C, Guan G, Zou C, Guo Q, Ren X, Li C, Cheng P, Cheng W, Wu A
JCI insight 2022 Dec 8;7(23)
JCI insight 2022 Dec 8;7(23)
Intestinal Stem Cells Damaged by Deoxycholic Acid via AHR Pathway Contributes to Mucosal Barrier Dysfunction in High-Fat Feeding Mice.
Liu L, Xu J, Xu X, Mao T, Niu W, Wu X, Lu L, Zhou H
International journal of molecular sciences 2022 Dec 8;23(24)
International journal of molecular sciences 2022 Dec 8;23(24)
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Zhou Y, Zhao Y, Ma W, Zhang L, Jiang Y, Dong W
Discover oncology 2022 Dec 8;13(1):136
Discover oncology 2022 Dec 8;13(1):136
Pan-cancer analysis of the prognostic and immunological role of PAQR4.
Wang K, Meng J, Wang X, Yan M, Liu S, Yang S, Xu S, Liu D, Li C, Yang K
Scientific reports 2022 Dec 8;12(1):21268
Scientific reports 2022 Dec 8;12(1):21268
Opuntia dillenii Haw. Polysaccharide Promotes Cholesterol Efflux in THP-1-Derived Foam Cells via the PPARγ-LXRα Signaling Pathway.
Li H, Huang Z, Zeng F
Molecules (Basel, Switzerland) 2022 Dec 7;27(24)
Molecules (Basel, Switzerland) 2022 Dec 7;27(24)
Role of Epidermal Growth Factor Receptor-Specific CAR-T Cells in the Suppression of Esophageal Squamous Cell Carcinoma.
Cheng C, Cui H, Liu H, Wu Y, Ding N, Weng Y, Zhang W, Cui Y
Cancers 2022 Dec 7;14(24)
Cancers 2022 Dec 7;14(24)
Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway.
Ma T, Wang X, Qu W, Yang L, Jing C, Zhu B, Zhang Y, Xie W
Molecules (Basel, Switzerland) 2022 Dec 6;27(23)
Molecules (Basel, Switzerland) 2022 Dec 6;27(23)
SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing.
He F, Yu Q, Wang M, Wang R, Gong X, Ge F, Yu X, Li S
Nature communications 2022 Dec 6;13(1):7526
Nature communications 2022 Dec 6;13(1):7526
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Li P, Wu J, Liu S, Lu R, Jiang H, Wang N, Luo M, Guo L, Xiao J, Bu L, Liu L, Xing F, Peng H, Li C, Ma L, Zhao B, Zhou Z, Guo D
Proceedings of the National Academy of Sciences of the United States of America 2022 Dec 6;119(49):e2205013119
Proceedings of the National Academy of Sciences of the United States of America 2022 Dec 6;119(49):e2205013119
Dendritic lipopeptide liposomes decorated with dual-targeted proteins.
Zhou S, Li C, Yuan Y, Jiang L, Chen W, Jiang X
Biomaterials science 2022 Dec 6;10(24):7032-7041
Biomaterials science 2022 Dec 6;10(24):7032-7041
Synthesis and anticancer activity of novel histone deacetylase inhibitors that inhibit autophagy and induce apoptosis.
Mo H, Zhang R, Chen Y, Li S, Wang Y, Zou W, Lin Q, Zhao DG, Du Y, Zhang K, Ma YY
European journal of medicinal chemistry 2022 Dec 5;243:114705
European journal of medicinal chemistry 2022 Dec 5;243:114705
Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model.
Li Q, Shi Y, Li X, Yang Y, Zhang X, Xu L, Ma Z, Wang J, Fan L, Wu L
International journal of molecular sciences 2022 Dec 4;23(23)
International journal of molecular sciences 2022 Dec 4;23(23)
A high efficient FVIII variant corrects bleeding in hemophilia A mouse model.
Mashausi DS, Roy D, Mangukiya HB, Merugu SB, Raza G, Yunus FU, Liu GS, Negi H, Li D
Biochemical and biophysical research communications 2022 Dec 31;637:358-364
Biochemical and biophysical research communications 2022 Dec 31;637:358-364
Baicalin regulates TLR4/IκBα/NFκB signaling pathway to alleviate inflammation in Doxorubicin related cardiotoxicity.
Feng P, Yang Y, Liu N, Wang S
Biochemical and biophysical research communications 2022 Dec 31;637:1-8
Biochemical and biophysical research communications 2022 Dec 31;637:1-8
Construction and validation of a prognostic model for osteosarcoma patients based on autophagy-related genes.
Ning B, Liu Y, Xu T, Li Y, Wei D, Huang T, Wei Y
Discover oncology 2022 Dec 31;13(1):146
Discover oncology 2022 Dec 31;13(1):146
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma.
Wei J, Yao J, Yang C, Mao Y, Zhu D, Xie Y, Liu P, Yan M, Ren L, Lin Y, Zheng Q, Li X
Journal of translational medicine 2022 Dec 3;20(1):555
Journal of translational medicine 2022 Dec 3;20(1):555
Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviors.
Wang J, Lai S, Zhou T, Xia Z, Li W, Sha W, Liu J, Chen Y
Journal of neuroinflammation 2022 Dec 29;19(1):318
Journal of neuroinflammation 2022 Dec 29;19(1):318
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Chen CC, Xie XM, Zhao XK, Zuo S, Li HY
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
A novel glycosylation-related gene signature predicts survival in patients with lung adenocarcinoma.
Liang JX, Chen Q, Gao W, Chen D, Qian XY, Bi JQ, Lin XC, Han BB, Liu JS
BMC bioinformatics 2022 Dec 27;23(1):562
BMC bioinformatics 2022 Dec 27;23(1):562
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Wu Y, Bao W, Ren J, Li C, Chen M, Zhang D, Zhu A
Genes 2022 Dec 27;14(1)
Genes 2022 Dec 27;14(1)
CPSF4 promotes tumor-initiating phenotype by enhancing VEGF/NRP2/TAZ signaling in lung cancer.
Song Y, Sun K, Gong L, Shi L, Qin T, Wang S, Deng W, Chen W, Zheng F, Li G
Medical oncology (Northwood, London, England) 2022 Dec 26;40(1):62
Medical oncology (Northwood, London, England) 2022 Dec 26;40(1):62
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
Cheng H, Guo Q, Zhao H, Liu K, Kang H, Gao F, Guo J, Yuan X, Hu S, Li F, Yang Q, Fang Z
International journal of molecular sciences 2022 Dec 26;24(1)
International journal of molecular sciences 2022 Dec 26;24(1)
Curcumol inhibits EMCV replication by activating CH25H and inhibiting the formation of ROs.
Zheng J, Sun P, Sun N, Hao Z, Fan K, Yin W, Khan A, Guo J, Zheng X, Li H
BMC veterinary research 2022 Dec 26;18(1):453
BMC veterinary research 2022 Dec 26;18(1):453
Peroxiredoxin 4 secreted by cumulus cells ameliorates the maturation of oocytes in vitro.
Dai W, Zou X, Jia H, Peng Y, La B, Yan Z, Gao L, Qin L, Diao F, Ma X, Meng Y, Cui Y, Liu J
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):155-161
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):155-161
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells.
Wang J, Li G, Lin M, Lin S, Wu L
BMC molecular and cell biology 2022 Dec 23;23(1):60
BMC molecular and cell biology 2022 Dec 23;23(1):60
Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets.
Zong Q, Qu H, Zhao Y, Liu H, Wu S, Wang S, Bao W, Cai D
Journal of animal science and biotechnology 2022 Dec 23;13(1):133
Journal of animal science and biotechnology 2022 Dec 23;13(1):133
Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation.
Koganti R, Yadavalli T, Sutar Y, Mallick S, Date A, Shukla D
iScience 2022 Dec 22;25(12):105682
iScience 2022 Dec 22;25(12):105682
Effect of Biodentine on Odonto/Osteogenic Differentiation of Human Dental Pulp Stem Cells.
Wang X, Cai Y, Zhang M, Xu J, Zhang C, Li J
Bioengineering (Basel, Switzerland) 2022 Dec 21;10(1)
Bioengineering (Basel, Switzerland) 2022 Dec 21;10(1)
Ruthenium red attenuates acute pancreatitis by inhibiting MCU and improving mitochondrial function.
Yu X, Dai C, Zhao X, Huang Q, He X, Zhang R, Lin Z, Shen Y
Biochemical and biophysical research communications 2022 Dec 20;635:236-243
Biochemical and biophysical research communications 2022 Dec 20;635:236-243
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
Shi X, Li X, Xu Z, Shen L, Ding Y, Chen S, Mao L, Liu W, Xu J
mBio 2022 Dec 20;13(6):e0228922
mBio 2022 Dec 20;13(6):e0228922
A lipid-polymer hybrid nanoparticle (LPN)-loaded dissolving microneedle patch for promoting hair regrowth by transdermal miR-218 delivery.
Zhao Y, Tian Y, Ye W, Wang X, Huai Y, Huang Q, Chu X, Deng X, Qian A
Biomaterials science 2022 Dec 20;11(1):140-152
Biomaterials science 2022 Dec 20;11(1):140-152
Distribution and characterization of extrachromosomal circular DNA in colorectal cancer.
Chen Z, Qi Y, He J, Xu C, Ge Q, Zhuo W, Si J, Chen S
Molecular biomedicine 2022 Dec 2;3(1):38
Molecular biomedicine 2022 Dec 2;3(1):38
CD59-Regulated Ras Compartmentalization Orchestrates Antitumor T-cell Immunity.
Li L, Ding P, Lv X, Xie S, Li L, Chen J, Zhou D, Wang X, Wang Q, Zhang W, Xu Y, Lu R, Hu W
Cancer immunology research 2022 Dec 2;10(12):1475-1489
Cancer immunology research 2022 Dec 2;10(12):1475-1489
Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance.
Dai M, Hua C, Wang M, Gao L, Jiang L, Liu Y
European journal of medical research 2022 Dec 19;27(1):299
European journal of medical research 2022 Dec 19;27(1):299
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
Xin Y, Wang J, Chu T, Zhou Y, Liu C, Xu A
Brain sciences 2022 Dec 17;12(12)
Brain sciences 2022 Dec 17;12(12)
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Qi Y, Xue HL, Zheng YJ, Yin YF, Xu WL, Xu JH, Wu M, Chen L, Xu LX
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Verteporfin inhibits the dedifferentiation of tubular epithelial cells via TGF-β1/Smad pathway but induces podocyte loss in diabetic nephropathy.
Qi C, Hu Y, Zeng M, Chen H, Shi J, Jue H, Zhao Z, Liu J, Zhang Z, Xu Y, Wu H
Life sciences 2022 Dec 15;311(Pt B):121186
Life sciences 2022 Dec 15;311(Pt B):121186
Complementary protective effects of autophagy and oxidative response against graphene oxide toxicity in Caenorhabditis elegans.
Dou T, Chen J, Wang R, Pu X, Wu H, Zhao Y
Ecotoxicology and environmental safety 2022 Dec 15;248:114289
Ecotoxicology and environmental safety 2022 Dec 15;248:114289
Developing a Naïve Bayesian Classification Model with PI3Kγ structural features for virtual screening against PI3Kγ: Combining molecular docking and pharmacophore based on multiple PI3Kγ conformations.
Jiang Y, Xiong W, Jia L, Xu L, Cai Y, Chen Y, Jin J, Gao M, Zhu J
European journal of medicinal chemistry 2022 Dec 15;244:114824
European journal of medicinal chemistry 2022 Dec 15;244:114824
Inhibition of BRD4 decreases fibrous scarring after ischemic stroke in rats by inhibiting the phosphorylation of Smad2/3.
Li X, Zhu H, Wen J, Huang J, Chen Y, Tian M, Ren J, Zhou L, Yang Q
Brain research 2022 Dec 15;1797:148126
Brain research 2022 Dec 15;1797:148126
Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes.
Cui L, Wang Y, Ren L, Li Z, Jiang Y, Wang C, Liu X, Ren Y, Hu X
Parasites & vectors 2022 Dec 13;15(1):464
Parasites & vectors 2022 Dec 13;15(1):464
Microalgae oil from Schizochytrium sp. alleviates obesity and modulates gut microbiota in high-fat diet-fed mice.
Ran L, Yu J, Ma R, Yao Q, Wang M, Bi Y, Yu Z, Wu Y
Food & function 2022 Dec 13;13(24):12799-12813
Food & function 2022 Dec 13;13(24):12799-12813
FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells.
Zhang Y, Yao E, Liu Y, Zhang Y, Ding M, Liu J, Chen X, Fan S
Cells 2022 Dec 13;11(24)
Cells 2022 Dec 13;11(24)
Effect of CTP-mediated PTEN on 5637 bladder cancer cells and the underlying molecular mechanism.
Yu B, Huang Y, Yang Y, Hu H, Yang J
BMC urology 2022 Dec 10;22(1):200
BMC urology 2022 Dec 10;22(1):200
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
Xue Y, Luo M, Hu X, Li X, Shen J, Zhu W, Huang L, Hu Y, Guo Y, Liu L, Wang L, Luo S
Communications biology 2022 Dec 1;5(1):1316
Communications biology 2022 Dec 1;5(1):1316
LPCAT1 functions as an oncogene in cervical cancer through mediating JAK2/STAT3 signaling.
Gao F, Chen J, Zhang T, Liu N
Experimental cell research 2022 Dec 1;421(1):113360
Experimental cell research 2022 Dec 1;421(1):113360
Novel indole-guanidine hybrids as potential anticancer agents: Design, synthesis and biological evaluation.
Li J, Si R, Zhang Q, Li Y, Zhang J, Shan Y
Chemico-biological interactions 2022 Dec 1;368:110242
Chemico-biological interactions 2022 Dec 1;368:110242
Glyphosate-induced mitochondrial reactive oxygen species overproduction activates parkin-dependent mitophagy to inhibit testosterone synthesis in mouse leydig cells.
Lu L, Liu JB, Wang JQ, Lian CY, Wang ZY, Wang L
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120314
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120314
Structural and functional insights into CST tethering in Tetrahymena thermophila telomerase.
Ma Y, Huang C, Tang T, Wu B, Xue H, Cao Y, Wu J, Wan B, Lei M
Structure (London, England : 1993) 2022 Dec 1;30(12):1565-1572.e4
Structure (London, England : 1993) 2022 Dec 1;30(12):1565-1572.e4
Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells.
Chen W, Yasen M, Wang H, Zhuang C, Wang Z, Lu S, Jiang L, Lin H
BMC pharmacology & toxicology 2022 Dec 1;23(1):90
BMC pharmacology & toxicology 2022 Dec 1;23(1):90
Optimisation and characterization of α-D-glucan produced by Bacillus velezensis RSDM1 and evaluation of its protective effect on oxidative stress in Tetrahymena thermophila induced by H(2)O(2).
Derdak R, Sakoui S, Pop OL, Vodnar DC, Addoum B, Teleky BE, Elemer S, Elmakssoudi A, Suharoschi R, Soukri A, El Khalfi B
International journal of biological macromolecules 2022 Dec 1;222(Pt B):3229-3242
International journal of biological macromolecules 2022 Dec 1;222(Pt B):3229-3242
Soybean soluble polysaccharide prevents obesity in high-fat diet-induced rats via lipid metabolism regulation.
He H, Chen C, Zhao W
International journal of biological macromolecules 2022 Dec 1;222(Pt B):3057-3065
International journal of biological macromolecules 2022 Dec 1;222(Pt B):3057-3065
Gastrodin improves neuroinflammation-induced cognitive dysfunction in rats by regulating NLRP3 inflammasome.
Zheng X, Gong T, Tang C, Zhong Y, Shi L, Fang X, Chen D, Zhu Z
BMC anesthesiology 2022 Dec 1;22(1):371
BMC anesthesiology 2022 Dec 1;22(1):371
FGF21 at physiological concentrations regulates vascular endothelial cell function through multiple pathways.
Yang N, Zhang Y, Huang Y, Yan J, Qian Z, Li H, Luo P, Yang Z, Luo M, Wei X, Nie H, Ruan L, Hao Y, Gao S, Zheng K, Zhang C, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166558
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166558
Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.
Yu D, Zhao XY, Meng QP, Teng D, Deng K, Lin N
Brain research 2022 Dec 1;1796:148109
Brain research 2022 Dec 1;1796:148109
IL-18BP Improves Early Graft Function and Survival in Lewis-Brown Norway Rat Orthotopic Liver Transplantation Model.
Meng Q, Wu W, Zhang W, Yuan J, Yang L, Zhang X, Tao K
Biomolecules 2022 Dec 1;12(12)
Biomolecules 2022 Dec 1;12(12)
METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma.
Li HB, Huang G, Tu J, Lv DM, Jin QL, Chen JK, Zou YT, Lee DF, Shen JN, Xie XB
EBioMedicine 2022 Aug;82:104142
EBioMedicine 2022 Aug;82:104142
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.
Wang JQ, Li LL, Hu A, Deng G, Wei J, Li YF, Liu YB, Lu XY, Qiu ZP, Shi XJ, Zhao X, Luo J, Song BL
Nature 2022 Aug;608(7922):413-420
Nature 2022 Aug;608(7922):413-420
LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis.
Zhang Y, Zheng M, Zhang L, Yuan P, Zhou J, Wang Y, Wang H
Biochemical genetics 2022 Aug;60(4):1298-1312
Biochemical genetics 2022 Aug;60(4):1298-1312
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Li J, Bu Y, Li B, Zhang H, Guo J, Hu J, Zhang Y
Journal of molecular histology 2022 Aug;53(4):713-727
Journal of molecular histology 2022 Aug;53(4):713-727
Enzymatic hydrolysate of porphyra enhances the intestinal mucosal functions in obese mice.
Li C, Cheng X, Cao W, Wang Y, Xue C, Tang Q
Journal of food biochemistry 2022 Aug;46(8):e14175
Journal of food biochemistry 2022 Aug;46(8):e14175
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Chen S, Huang Y, Su H, Zhu W, Wei Y, Long Y, Shi Y, Wei J
Inflammation 2022 Aug;45(4):1780-1799
Inflammation 2022 Aug;45(4):1780-1799
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Liu C, Li Y, Wang X
Inflammation 2022 Aug;45(4):1520-1533
Inflammation 2022 Aug;45(4):1520-1533
Farnesoid X receptor contributes to oleanolic acid-induced cholestatic liver injury in mice.
Feng H, Hu Y, Zhou S, Lu Y
Journal of applied toxicology : JAT 2022 Aug;42(8):1323-1336
Journal of applied toxicology : JAT 2022 Aug;42(8):1323-1336
Electroacupuncture attenuates pulmonary vascular remodeling in a rat model of chronic obstructive pulmonary disease via the VEGF/PI3K/Akt pathway.
Zhang L, Tian Y, Zhao P, Jin F, Miao Y, Liu Y, Li J
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2022 Aug;40(4):389-400
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2022 Aug;40(4):389-400
Electroacupuncture alleviates anxiety and modulates amygdala CRH/CRHR1 signaling in single prolonged stress mice.
Zhu J, Wang C, Wang Y, Guo C, Lu P, Mou F, Shao S
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2022 Aug;40(4):369-378
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2022 Aug;40(4):369-378
FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells.
Zhao F, Ge F, Xie M, Li Z, Zang C, Kong L, Pu Y, Zheng X, Tan Y
Clinical & experimental metastasis 2022 Aug;39(4):623-639
Clinical & experimental metastasis 2022 Aug;39(4):623-639
KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B.
Liu Y, Tian X, Ke P, Gu J, Ma Y, Guo Y, Xu X, Chen Y, Yang M, Wang X, Xiao F
Neuroscience bulletin 2022 Aug;38(8):841-856
Neuroscience bulletin 2022 Aug;38(8):841-856
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
Jiang J, Cheng Y, Dai S, Zou B, Guo X
Environmental toxicology 2022 Aug;37(8):1944-1956
Environmental toxicology 2022 Aug;37(8):1944-1956
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis.
Fang Q, Liu J, Chen L, Chen Q, Wang Y, Li Z, Fu W, Liu Y
Metabolic brain disease 2022 Aug;37(6):2077-2088
Metabolic brain disease 2022 Aug;37(6):2077-2088
DDX3X alleviates doxorubicin-induced cardiotoxicity by regulating Wnt/β-catenin signaling pathway in an in vitro model.
Feng D, Li J, Guo L, Liu J, Wang S, Ma X, Song Y, Liu J, Hao E
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23077
Journal of biochemical and molecular toxicology 2022 Aug;36(8):e23077
Extracellular HSP90α promotes cellular senescence by modulating TGF-β signaling in pulmonary fibrosis.
Zhong W, Chen W, Liu Y, Zhang J, Lu Y, Wan X, Qiao Y, Huang H, Zeng Z, Li W, Meng X, Zhao H, Zou M, Cai S, Dong H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Aug;36(8):e22475
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Aug;36(8):e22475
NEAT1 in bone marrow mesenchymal stem cell-derived extracellular vesicles promotes melanoma by inducing M2 macrophage polarization.
Yang Y, Ma S, Ye Z, Zheng Y, Zheng Z, Liu X, Zhou X
Cancer gene therapy 2022 Aug;29(8-9):1228-1239
Cancer gene therapy 2022 Aug;29(8-9):1228-1239
CDK12 activates MYC to repress miR-28-5p/EZH2 and amplifies tonic BCR signaling to promote the development of diffuse large B-cell lymphoma.
Liu QH, Dai GR, Wang XN, Wang L, Li LL, Wu ZS, Xia RX
Cancer gene therapy 2022 Aug;29(8-9):1207-1216
Cancer gene therapy 2022 Aug;29(8-9):1207-1216
Interaction between gut microbiota dysbiosis and lung infection as gut-lung axis caused by Streptococcus suis in mouse model.
Yang W, Ansari AR, Niu X, Zou W, Lu M, Dong L, Li F, Chen Y, Yang K, Song H
Microbiological research 2022 Aug;261:127047
Microbiological research 2022 Aug;261:127047
A novel 7‑hypoxia‑related long non‑coding RNA signature associated with prognosis and proliferation in melanoma.
Luo Y, Li T, Zhao H, Chen A
Molecular medicine reports 2022 Aug;26(2)
Molecular medicine reports 2022 Aug;26(2)
Skeletal muscle MiR-210 expression is associated with mitochondrial function in peripheral artery disease patients.
Ismaeel A, Fletcher E, Miserlis D, Wechsler M, Papoutsi E, Haynatzki G, Smith RS, Bohannon WT, Koutakis P
Translational research : the journal of laboratory and clinical medicine 2022 Aug;246:66-77
Translational research : the journal of laboratory and clinical medicine 2022 Aug;246:66-77
Long non-coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR-326/PKM2 axis.
Wang Y, Yang F, Peng Q, Mei K, He H, Yang Q
The journal of gene medicine 2022 Aug;24(8):e3440
The journal of gene medicine 2022 Aug;24(8):e3440
Protective role of Achyranthes bidentata polysaccharides against chondrocyte extracellular matrix degeneration through lncRNA GAS5 in osteoarthritis.
Fu C, Qiu Z, Huang Y, Mei Y, Lin Q, Zeng J, Zhong W, Ma D
Experimental and therapeutic medicine 2022 Aug;24(2):532
Experimental and therapeutic medicine 2022 Aug;24(2):532
PVT1 promotes resistance to 5-FU in colon cancer via the miR-486-5p/CDK4 axis.
Luo Z, Chen R, Hu S, Huang X, Huang Z
Oncology letters 2022 Aug;24(2):280
Oncology letters 2022 Aug;24(2):280
miR-let-7c-3p targeting on Egr-1 contributes to the committed differentiation of leukemia cells into monocyte/macrophages.
Qi F, Wang X, Zhao S, Wang C, Sun R, Wang H, Du P, Wang J, Wang X, Jiang G
Oncology letters 2022 Aug;24(2):273
Oncology letters 2022 Aug;24(2):273
In vitro experimental study on the formation of microRNA-34a loaded exosomes and their inhibitory effect in oral squamous cell carcinoma.
Deng W, Meng Y, Wang B, Wang CX, Hou CX, Zhu QH, Tang YT, Ye JH
Cell cycle (Georgetown, Tex.) 2022 Aug;21(16):1775-1783
Cell cycle (Georgetown, Tex.) 2022 Aug;21(16):1775-1783
High VHL Expression Reverses Warburg Phenotype and Enhances Immunogenicity in Kidney Tumor Cells.
Zhu S, Ding W, Chen Y, Wang W, Xu R, Liu C, Liu X, Deng H
Genomics, proteomics & bioinformatics 2022 Aug;20(4):657-669
Genomics, proteomics & bioinformatics 2022 Aug;20(4):657-669
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes.
Yan B, Liu P, Yi X, Li J, Liu N, Zhu W, Kuang Y, Chen X, Peng C
Pharmacological research 2022 Aug;182:106318
Pharmacological research 2022 Aug;182:106318
Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
Wei W, Li Y, Wang C, Gao S, Zhao Y, Yang Z, Wang H, Gao Z, Jiang Y, He Y, Zhao L, Gao H, Yao X, Hu Y
Pharmacological research 2022 Aug;182:106285
Pharmacological research 2022 Aug;182:106285
Zinc-doped Prussian blue nanoparticles for mutp53-carrying tumor ion interference and photothermal therapy.
Jin Q, Zuo W, Lin Q, Wu T, Liu C, Liu N, Liu J, Zhu X
Asian journal of pharmaceutical sciences 2022 Aug;17(5):767-777
Asian journal of pharmaceutical sciences 2022 Aug;17(5):767-777
α-Terthienyl induces prostate cancer cell death through inhibiting androgen receptor expression.
Gan X, Huang H, Wen J, Liu K, Yang Y, Li X, Fang G, Liu Y, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113266
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113266
Dioscin alleviates Alzheimer's disease through regulating RAGE/NOX4 mediated oxidative stress and inflammation.
Guan L, Mao Z, Yang S, Wu G, Chen Y, Yin L, Qi Y, Han L, Xu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113248
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113248
β-cryptoxanthin alleviates myocardial ischaemia/reperfusion injury by inhibiting NF-κB-mediated inflammatory signalling in rats.
Zhang F, Shi D, Wang X, Zhang Y, Duan W, Li Y
Archives of physiology and biochemistry 2022 Aug;128(4):1128-1135
Archives of physiology and biochemistry 2022 Aug;128(4):1128-1135
Circulating Exosomes from Mice with LPS-Induced Bone Loss Inhibit Osteoblast Differentiation.
Wang Y, Zhang L, Wang K, Zhou H, Li G, Xu L, Hu Z, Cao X, Shi F, Zhang S
Calcified tissue international 2022 Aug;111(2):185-195
Calcified tissue international 2022 Aug;111(2):185-195
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
Bao C, Liu C, Liu Q, Hua L, Hu J, Li Z, Xu S
International immunopharmacology 2022 Aug;109:108770
International immunopharmacology 2022 Aug;109:108770
IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation.
Wu X, Ming B, Wu T, Gao R, Hu P, Tang J, Zhong J, Zheng F, Dong L
Journal of dermatological science 2022 Aug;107(2):95-104
Journal of dermatological science 2022 Aug;107(2):95-104
Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.
Yong T, Liang D, Chen S, Xiao C, Gao X, Wu Q, Xie Y, Huang L, Hu H, Li X, Liu Y, Cai M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154256
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154256
Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer.
Queiroz AL, Dantas E, Ramsamooj S, Murthy A, Ahmed M, Zunica ERM, Liang RJ, Murphy J, Holman CD, Bare CJ, Ghahramani G, Wu Z, Cohen DE, Kirwan JP, Cantley LC, Axelrod CL, Goncalves MD
Nature communications 2022 Aug 8;13(1):4633
Nature communications 2022 Aug 8;13(1):4633
A yeast-based system to study SARS-CoV-2 M (pro) structure and to identify nirmatrelvir resistant mutations.
Ou J, Lewandowski EM, Hu Y, Lipinski AA, Morgan RT, Jacobs LMC, Zhang X, Bikowitz MJ, Langlais P, Tan H, Wang J, Chen Y, Choy JS
bioRxiv : the preprint server for biology 2022 Aug 8;
bioRxiv : the preprint server for biology 2022 Aug 8;
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson's Disease Model.
Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J
Molecules (Basel, Switzerland) 2022 Aug 6;27(15)
Molecules (Basel, Switzerland) 2022 Aug 6;27(15)
Discovery of highly potent and selective CRBN-recruiting EGFR(L858R/T790M) degraders in vivo.
Zhang W, Li P, Sun S, Jia C, Yang N, Zhuang X, Zheng Z, Li S
European journal of medicinal chemistry 2022 Aug 5;238:114509
European journal of medicinal chemistry 2022 Aug 5;238:114509
Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance.
Xu G, Chen H, Wu S, Chen J, Zhang S, Shao G, Sun L, Mu Y, Liu K, Pan Q, Li N, An X, Lin S, Chen W
Cell death & disease 2022 Aug 5;13(8):683
Cell death & disease 2022 Aug 5;13(8):683
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
Xu B, Wei Y, Liu F, Li L, Zhou S, Peng Y, Li B
Cell death discovery 2022 Aug 4;8(1):348
Cell death discovery 2022 Aug 4;8(1):348
RBM45 is an m(6)A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs.
Choi SH, Flamand MN, Liu B, Zhu H, Hu M, Wang M, Sewell J, Holley CL, Al-Hashimi HM, Meyer KD
Cell reports 2022 Aug 30;40(9):111293
Cell reports 2022 Aug 30;40(9):111293
Upregulation of Spinal miR-155-5p Contributes to Mechanical Hyperalgesia by Promoting Inflammatory Activation of Microglia in Bone Cancer Pain Rats.
Jian Y, Song Z, Ding Z, Wang J, Wang R, Hou X
Life (Basel, Switzerland) 2022 Aug 30;12(9)
Life (Basel, Switzerland) 2022 Aug 30;12(9)
Intestinal Klebsiella pneumoniae Contributes to Pneumonia by Synthesizing Glutamine in Multiple Myeloma.
Wang Y, Yang Q, Zhu Y, Jian X, Guo J, Zhang J, Kuang C, Feng X, An G, Qiu L, Li G, He Y, Zhou W
Cancers 2022 Aug 29;14(17)
Cancers 2022 Aug 29;14(17)
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Liu D, Sun H, Li K, Zhao Z, Liu Z, Zhang G, Ge Y, Zhang J, Wang D, Leng Y
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs.
Wang Q, Cao Y, Shen L, Xiao T, Cao R, Wei S, Tang M, Du L, Wu H, Wu B, Yu Y, Wang S, Wen M, OuYang B
Science advances 2022 Aug 26;8(34):eabq4722
Science advances 2022 Aug 26;8(34):eabq4722
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Liu M, Yue Z, Zhang B, Li F, Liu L, Li F
Metabolites 2022 Aug 25;12(9)
Metabolites 2022 Aug 25;12(9)
Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.
Hu H, Yang X, He Y, Duan C, Sun N
Journal of neuroinflammation 2022 Aug 24;19(1):208
Journal of neuroinflammation 2022 Aug 24;19(1):208
Enhancing Tumor Therapy of Fe(III)-Shikonin Supramolecular Nanomedicine via Triple Ferroptosis Amplification.
Feng W, Shi W, Wang Z, Cui Y, Shao X, Liu S, Rong L, Liu Y, Zhang H
ACS applied materials & interfaces 2022 Aug 24;14(33):37540-37552
ACS applied materials & interfaces 2022 Aug 24;14(33):37540-37552
Alteration of E2F2 Expression in Governing Endothelial Cell Senescence.
Liu H, Chen L, Xiao W, Liu J, Long C, Zhan W, Cui C, Yang L, Chen S
Genes 2022 Aug 24;13(9)
Genes 2022 Aug 24;13(9)
Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway.
Feng S, Xie X, Chen C, Zuo S, Zhao X, Li H
Nutrition & metabolism 2022 Aug 23;19(1):57
Nutrition & metabolism 2022 Aug 23;19(1):57
Role of dual specificity phosphatases (DUSPs) in melanoma cellular plasticity and drug resistance.
Singh MK, Altameemi S, Lares M, Newton MA, Setaluri V
Scientific reports 2022 Aug 23;12(1):14395
Scientific reports 2022 Aug 23;12(1):14395
The mechanism on Prevotella melaninogenica promoting the inflammatory progression of oral lichen planus.
Xu P, Shao RR, Zhang S, Tan ZW, Guo YT, He Y
Clinical and experimental immunology 2022 Aug 19;209(2):215-224
Clinical and experimental immunology 2022 Aug 19;209(2):215-224
Plasma Proteomic Profiling Reveals the Regulatory Factors of Milk Protein Synthesis in Holstein Cows.
Wang X, Xu J, Han Z
Biology 2022 Aug 19;11(8)
Biology 2022 Aug 19;11(8)
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Wang J, He Z, Liu X, Xu J, Jiang X, Quan G, Jiang J
Cell death & disease 2022 Aug 18;13(8):718
Cell death & disease 2022 Aug 18;13(8):718
Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy.
Sun X, Yang Y, Sun X, Meng H, Hao W, Yin J, Ma F, Guo X, Du L, Sun L, Wu H
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9865-9876
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9865-9876
PGE(2) -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase.
Tao X, Du R, Guo S, Feng X, Yu T, OuYang Q, Chen Q, Fan X, Wang X, Guo C, Li X, Xue F, Chen S, Tong M, Lazarus M, Zuo S, Yu Y, Shen Y
The EMBO journal 2022 Aug 16;41(16):e110439
The EMBO journal 2022 Aug 16;41(16):e110439
SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity.
Meng B, Datir R, Choi J, CITIID-NIHR Bioresource COVID-19 Collaboration, Bradley JR, Smith KGC, Lee JH, Gupta RK
Cell reports 2022 Aug 16;40(7):111220
Cell reports 2022 Aug 16;40(7):111220
Matrine induces autophagy in human neuroblastoma cells via blocking the AKT-mTOR pathway.
Liu N, Yang C, Yang L, Li T, Gong M, Wang H, Zhang J, Zhao H, Zou L, He X
Medical oncology (Northwood, London, England) 2022 Aug 16;39(11):167
Medical oncology (Northwood, London, England) 2022 Aug 16;39(11):167
A novel mutation located in the intermembrane space domain of AFG3L2 causes dominant optic atrophy through decreasing the stability of the encoded protein.
Yang L, Jin X, Li Y, Guo Q, Yang M, You Y, Yao S, Zhang X, Wang Z, Lei B
Cell death discovery 2022 Aug 15;8(1):361
Cell death discovery 2022 Aug 15;8(1):361
Tri-n-butyl phosphate delays tissue repair by dysregulating neutrophil function in zebrafish.
Wang Y, Cheng Z, Zhang H, Li S, Pan Y, Zhang W, Huang S, He X, Zou F, Yuan Z, Yan W, Huang H
Toxicology and applied pharmacology 2022 Aug 15;449:116114
Toxicology and applied pharmacology 2022 Aug 15;449:116114
Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling.
Zhu P, Jin Z, Kang G, Jia Y, Liu D, Zhang Q, Guo F, Jia Y, Jiao Y, Li J, Sun H, Ma X
Cell communication and signaling : CCS 2022 Aug 15;20(1):121
Cell communication and signaling : CCS 2022 Aug 15;20(1):121
Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats.
Yan W, Hao F, Zhe X, Wang Y, Liu D
BMC veterinary research 2022 Aug 15;18(1):313
BMC veterinary research 2022 Aug 15;18(1):313
Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verification.
Chen W, Lin Y, Jiang M, Wang Q, Shu Q
Journal of translational medicine 2022 Aug 12;20(1):355
Journal of translational medicine 2022 Aug 12;20(1):355
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
Li C, Zheng H, Xiong J, Huang Y, Li H, Jin H, Ai S, Wang Y, Su T, Sun G, Xiao X, Fu T, Wang Y, Gao X, Liang P
Cell death & disease 2022 Aug 12;13(8):699
Cell death & disease 2022 Aug 12;13(8):699
Characterization of Mesothelin Glycosylation in Pancreatic Cancer: Decreased Core Fucosylated Glycoforms in Pancreatic Cancer Patients' Sera.
Duran A, Guerrero PE, Ortiz MR, Pérez Del Campo D, Castro E, Garcia-Velasco A, Fort E, de Llorens R, Saldova R, Llop E, Peracaula R
Biomedicines 2022 Aug 10;10(8)
Biomedicines 2022 Aug 10;10(8)
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Overexpression of MLF1IP promotes colorectal cancer cell proliferation through BRCA1/AKT/p27 signaling pathway.
Xu Y, Zhang L, Wang Q, Zheng M
Cellular signalling 2022 Apr;92:110273
Cellular signalling 2022 Apr;92:110273
Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer.
Liu F, Li X, Yan H, Wu J, Yang Y, He J, Chen J, Jiang Z, Wu F, Jiang Z
Cellular signalling 2022 Apr;92:110267
Cellular signalling 2022 Apr;92:110267
Activation of microglial GPR109A alleviates thermal hyperalgesia in female lupus mice by suppressing IL-18 and glutamatergic synaptic activity.
Viatchenko-Karpinski V, Kong L, Weng HR
Glia 2022 Apr;70(4):634-649
Glia 2022 Apr;70(4):634-649
Letrozole promotes the expression of integrin αvβ3 and HOXA10 in endometrium of endometriosis.
Zhang J, Wang L, Li C, Zhang H, Li R, Li M
Systems biology in reproductive medicine 2022 Apr;68(2):121-128
Systems biology in reproductive medicine 2022 Apr;68(2):121-128
COP1 Acts as a Ubiquitin Ligase for PCDH9 Ubiquitination and Degradation in Human Glioma.
Zhou K, Wang L, Sun Z, Liu Y, Zhu Y, Liu Z, Zhang B, Shi H
Molecular neurobiology 2022 Apr;59(4):2378-2388
Molecular neurobiology 2022 Apr;59(4):2378-2388
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
Yu K, Tan Z, Xin Y
Molecular biology reports 2022 Apr;49(4):2785-2793
Molecular biology reports 2022 Apr;49(4):2785-2793
NLRP2 inhibits cell proliferation and migration by regulating EMT in lung adenocarcinoma cells.
Li T, Li X, Mao R, Pan L, Que Y, Zhu C, Jin L, Li S
Cell biology international 2022 Apr;46(4):588-598
Cell biology international 2022 Apr;46(4):588-598
Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma.
Han P, Wu S, Li L, Li D, Zhao J, Zhang H, Wang Y, Zhong X, Zhang Z, Li P, Matskova L, Zhou X
Genes & genomics 2022 Apr;44(4):487-497
Genes & genomics 2022 Apr;44(4):487-497
Inhibiting uptake activity of organic anion transporter 2 by bile acids.
Wang Y, Hu H, Nie J, Zhou H, Yu L, Zeng S
Drug metabolism and pharmacokinetics 2022 Apr;43:100448
Drug metabolism and pharmacokinetics 2022 Apr;43:100448
C1q/tumor necrosis factor-related protein 9 protects cultured chondrocytes from IL-1β-induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis.
Wang B, Li Y, Hu S, Peng K
Environmental toxicology 2022 Apr;37(4):889-898
Environmental toxicology 2022 Apr;37(4):889-898
FAM83A has a pro-tumor function in ovarian cancer by affecting the Akt/Wnt/β-catenin pathway.
Zhao J, Zhao F, Yang T, Tian S, Zhao M, Wang S, Yang X
Environmental toxicology 2022 Apr;37(4):695-707
Environmental toxicology 2022 Apr;37(4):695-707
Hsa_circRNA_0017620 regulated cell progression of non-small-cell lung cancer via miR-520a-5p/KRT5 axis.
Chen S, Hong K, Zhou L, Ran R, Huang J, Zheng Y, Xing M, Cai Y
Journal of clinical laboratory analysis 2022 Apr;36(4):e24347
Journal of clinical laboratory analysis 2022 Apr;36(4):e24347
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway.
Hu W, Cai C, Li Y, Kang F, Chu T, Dong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22243
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22243
Phylogenetic convergence of phase separation and mitotic function in the disordered protein BuGZ.
Chin AF, Zheng Y, Hilser VJ
Protein science : a publication of the Protein Society 2022 Apr;31(4):822-834
Protein science : a publication of the Protein Society 2022 Apr;31(4):822-834
Circadian rhythm modulates endochondral bone formation via MTR1/AMPKβ1/BMAL1 signaling axis.
Yu S, Tang Q, Chen G, Lu X, Yin Y, Xie M, Long Y, Zheng W, Guo F, Shao L, Shi A, Chen L
Cell death and differentiation 2022 Apr;29(4):874-887
Cell death and differentiation 2022 Apr;29(4):874-887
DEC1 promotes progression of Helicobacter pylori-positive gastric cancer by regulating Akt/NF-κB pathway.
Jia Y, Liu Y, Zhu J, Liu L, Ma X, Liu D, Han S, Zhang L, Ling ZQ, Wang Y
Journal of cellular and molecular medicine 2022 Apr;26(7):1943-1954
Journal of cellular and molecular medicine 2022 Apr;26(7):1943-1954
Apatinib inhibits tumour progression and promotes antitumour efficacy of cytotoxic drugs in oesophageal squamous cell carcinoma.
Chi Y, Wang F, Zhang Y, Shan Z, Tao W, Lian Y, Xin D, Fan Q, Sun Y
Journal of cellular and molecular medicine 2022 Apr;26(7):1905-1917
Journal of cellular and molecular medicine 2022 Apr;26(7):1905-1917
Apelin-13/APJ induces cardiomyocyte hypertrophy by activating the Pannexin-1/P2X7 axis and FAM134B-dependent reticulophagy.
Yang Y, Zhang K, Huang S, Chen W, Mao H, Ouyang X, Chen L, Li L
Journal of cellular physiology 2022 Apr;237(4):2230-2248
Journal of cellular physiology 2022 Apr;237(4):2230-2248
Salidroside suppresses the activation of nasopharyngeal carcinoma cells via targeting miR-4262/GRP78 axis.
Liu S, Li Y, Li Z
Cell cycle (Georgetown, Tex.) 2022 Apr;21(7):720-729
Cell cycle (Georgetown, Tex.) 2022 Apr;21(7):720-729
Glucagon-like peptide-1 receptor agonist attenuates diabetic neuropathic pain via inhibition of NOD-like receptor protein 3 inflammasome in brain microglia.
Zhang Q, Li Q, Liu S, Zheng H, Ji L, Yi N, Bao W, Zhu X, Sun W, Liu X, Zhang S, Zuo C, Li Y, Xiong Q, Lu B
Diabetes research and clinical practice 2022 Apr;186:109806
Diabetes research and clinical practice 2022 Apr;186:109806
PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence.
Wang G, Zhao Y, Zhou Y, Jiang L, Liang L, Kong F, Yan Y, Wang X, Wang Y, Wen X, Zeng X, Tian G, Deng G, Shi J, Liu L, Chen H, Li C
PLoS pathogens 2022 Apr;18(4):e1010446
PLoS pathogens 2022 Apr;18(4):e1010446
Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy.
Wang L, Zhao C, Zheng T, Zhang Y, Liu H, Wang X, Tang X, Zhao B, Liu P
Autophagy 2022 Apr;18(4):765-782
Autophagy 2022 Apr;18(4):765-782
GALNT4 primes monocytes adhesion and transmigration by regulating O-Glycosylation of PSGL-1 in atherosclerosis.
Ye Z, Guo H, Wang L, Li Y, Xu M, Zhao X, Song X, Chen Z, Huang R
Journal of molecular and cellular cardiology 2022 Apr;165:54-63
Journal of molecular and cellular cardiology 2022 Apr;165:54-63
PI3K inhibitor 3-MA promotes the antiproliferative activity of esomeprazole in gastric cancer cells by downregulating EGFR via the PI3K/FOXO3a pathway.
Du J, Xu Q, Zhao H, Jia X, Ba N, Peng F, Zhang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112665
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112665
MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2.
Zhang Y, Lin W, Jiang W, Wang Z
Bioengineered 2022 Apr;13(4):9959-9972
Bioengineered 2022 Apr;13(4):9959-9972
Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9.
Wang C, Wang Y, Liu C, Meng X, Hang Z
Bioengineered 2022 Apr;13(4):9495-9507
Bioengineered 2022 Apr;13(4):9495-9507
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
Liu Z, Xu B, Ding Y, Ding X, Yang Z
Bioengineered 2022 Apr;13(4):9357-9368
Bioengineered 2022 Apr;13(4):9357-9368
Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2.
Cao W, Tian R, Pan R, Sun B, Xiao C, Chen Y, Zeng Z, Lei S
Bioengineered 2022 Apr;13(4):8643-8656
Bioengineered 2022 Apr;13(4):8643-8656
Fat mass and obesity associated (FTO)-mediated N6-methyladenosine modification of Krüppel-like factor 3 (KLF3) promotes osteosarcoma progression.
Shan HJ, Gu WX, Duan G, Chen HL
Bioengineered 2022 Apr;13(4):8038-8050
Bioengineered 2022 Apr;13(4):8038-8050
MEK1/2 inhibitor inhibits neointima formation by activating miR-126-3p/ C-X-C motif chemokine ligand 12 (CXCL12)/C-X-C motif chemokine receptor 4 (CXCR4) axis.
Yan Y, Zhu M, Ma J, He X, Yang X, Xu H, Jiang M, Zhang S, Duan Y, Han J, Chen Y
Bioengineered 2022 Apr;13(4):11214-11227
Bioengineered 2022 Apr;13(4):11214-11227
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Chen G, Lian D, Zhao L, Wang Z, Wuyun Q, Zhang N
Bioengineered 2022 Apr;13(4):11083-11095
Bioengineered 2022 Apr;13(4):11083-11095
Heat shock factor 2-binding protein promotes tumor progression via activation of MAPK signaling pathway in lung adenocarcinoma.
Liu J, Zhang Y, Tao J, Yu T, Zhang T
Bioengineered 2022 Apr;13(4):10324-10334
Bioengineered 2022 Apr;13(4):10324-10334
Long non-coding RNA NRAV enhances proliferation and invasion of hepatocellular carcinoma cells by modulating the Wnt/β-catenin signaling pathway.
Wang Q, Tang Y, Ge Y, Zhang S, Zheng M
Bioengineered 2022 Apr;13(4):10026-10037
Bioengineered 2022 Apr;13(4):10026-10037
Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy.
Yao Y, Chen H, Tan N
Acta pharmaceutica Sinica. B 2022 Apr;12(4):2103-2119
Acta pharmaceutica Sinica. B 2022 Apr;12(4):2103-2119
PLOD3 regulates the expression of YAP1 to affect the progression of non-small cell lung cancer via the PKCδ/CDK1/LIMD1 signaling pathway.
Li WH, Huang K, Wen FB, Cui GH, Guo HZ, Zhao S
Laboratory investigation; a journal of technical methods and pathology 2022 Apr;102(4):440-451
Laboratory investigation; a journal of technical methods and pathology 2022 Apr;102(4):440-451
miR-21 antagonist alleviates colitis and angiogenesis via the PTEN/PI3K/AKT pathway in colitis mice induced by TNBS.
Xie X, Liu P, Wu H, Li H, Tang Y, Chen X, Xu C, Liu X, Dai G
Annals of translational medicine 2022 Apr;10(7):413
Annals of translational medicine 2022 Apr;10(7):413
MPZ gene variant site in Chinese patients with Charcot-Marie-Tooth disease.
Hao X, Li C, Lv Y, Zhou T, Tian H, Ma Y, Ding J, Li X, Wang Y, Wang L, Yang P
Molecular genetics & genomic medicine 2022 Apr;10(4):e1890
Molecular genetics & genomic medicine 2022 Apr;10(4):e1890
Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer.
Lin F, Li X, Wang X, Sun H, Wang Z, Wang X
Journal of experimental & clinical cancer research : CR 2022 Apr 7;41(1):129
Journal of experimental & clinical cancer research : CR 2022 Apr 7;41(1):129
Gadolinium-based contrast agent accelerates the migration of astrocyte via integrin αvβ3 signaling pathway.
Ariyani W, Miyazaki W, Tsushima Y, Koibuchi N
Scientific reports 2022 Apr 7;12(1):5850
Scientific reports 2022 Apr 7;12(1):5850
Architecture of the human NALCN channelosome.
Zhou L, Liu H, Zhao Q, Wu J, Yan Z
Cell discovery 2022 Apr 6;8(1):33
Cell discovery 2022 Apr 6;8(1):33
Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway.
Qin X, Chen X, Guo L, Liu J, Yang Y, Zeng Y, Li C, Liu W, Ma W
BMC complementary medicine and therapies 2022 Apr 6;22(1):100
BMC complementary medicine and therapies 2022 Apr 6;22(1):100
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma.
Jia X, Li L, Wang F, Xue Y, Wu T, Jia Q, Li Y, Wu C, Chen Y, Wu J, Su Y, Wang X, Zhuang T, Dong X, Ling J, Yuan J, Li Q
Cell death discovery 2022 Apr 5;8(1):166
Cell death discovery 2022 Apr 5;8(1):166
M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation.
Lv C, Li S, Zhao J, Yang P, Yang C
ACS omega 2022 Apr 5;7(13):11405-11414
ACS omega 2022 Apr 5;7(13):11405-11414
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease.
Šušnjar U, Škrabar N, Brown AL, Abbassi Y, Phatnani H, NYGC ALS Consortium, Cortese A, Cereda C, Bugiardini E, Cardani R, Meola G, Ripolone M, Moggio M, Romano M, Secrier M, Fratta P, Buratti E
Communications biology 2022 Apr 5;5(1):314
Communications biology 2022 Apr 5;5(1):314
Male infertility-associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery.
Zhao H, Sun J, Insinna C, Lu Q, Wang Z, Nagashima K, Stauffer J, Andresson T, Specht S, Perera S, Daar IO, Westlake CJ
EMBO reports 2022 Apr 5;23(4):e52775
EMBO reports 2022 Apr 5;23(4):e52775
ATP6AP2 knockdown in cardiomyocyte deteriorates heart function via compromising autophagic flux and NLRP3 inflammasome activation.
Li L, Cui YJ, Liu Y, Li HX, Su YD, Li SN, Wang LL, Zhao YW, Wang SX, Yan F, Dong B
Cell death discovery 2022 Apr 4;8(1):161
Cell death discovery 2022 Apr 4;8(1):161
Effect of allisartan on blood pressure and left ventricular hypertrophy through Kv1.5 channels in hypertensive rats.
Xu C, Zhao Z, Yuan W, Fengping Z, Zhiqiang Y, Xiaoqin Z
Clinical and experimental hypertension (New York, N.Y. : 1993) 2022 Apr 3;44(3):199-207
Clinical and experimental hypertension (New York, N.Y. : 1993) 2022 Apr 3;44(3):199-207
Structure-Based Discovery of MDM2/4 Dual Inhibitors that Exert Antitumor Activities against MDM4-Overexpressing Cancer Cells.
Zhang S, Yan Z, Li Y, Gong Y, Lyu X, Lou J, Zhang D, Meng X, Zhao Y
Journal of medicinal chemistry 2022 Apr 28;65(8):6207-6230
Journal of medicinal chemistry 2022 Apr 28;65(8):6207-6230
Mechanical stimulation promotes enthesis injury repair by mobilizing Prrx1(+) cells via ciliary TGF-β signaling.
Xiao H, Zhang T, Li C, Cao Y, Wang L, Chen H, Li S, Guan C, Hu J, Chen D, Chen C, Lu H
eLife 2022 Apr 27;11
eLife 2022 Apr 27;11
Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages.
Qian Z, Liu C, Li H, Yang H, Wu J, Liu J, Li Y, Chen X, Xu J, Li X
Biomedicines 2022 Apr 27;10(5)
Biomedicines 2022 Apr 27;10(5)
EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism.
Yu PW, Fu PF, Zeng L, Qi YL, Li XQ, Wang Q, Yang GY, Li HW, Wang J, Chu BB, Wang MD
Microbiology spectrum 2022 Apr 27;10(2):e0227621
Microbiology spectrum 2022 Apr 27;10(2):e0227621
IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis.
Gou X, Xu W, Liu Y, Peng Y, Xu W, Yin Y, Zhang X
Microbiology spectrum 2022 Apr 27;10(2):e0204921
Microbiology spectrum 2022 Apr 27;10(2):e0204921
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Wang T, Chen Z, Chen H, Yu X, Wang L, Liu X
Journal of ethnopharmacology 2022 Apr 24;288:115020
Journal of ethnopharmacology 2022 Apr 24;288:115020
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
Zhang ZH, Cao XC, Peng JY, Huang SL, Chen C, Jia SZ, Ni JZ, Song GL
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
[Protective effect of Epothilone D against traumatic optic nerve injury in rats].
Wang P, Luo S, Shen C, Yu Z, Nie Z, Li Z, Wen J, Li M, Cao X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Apr 20;42(4):575-583
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Apr 20;42(4):575-583
Relationship between Neuroprotective Effects and Structure of Procyanidins.
Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J
Molecules (Basel, Switzerland) 2022 Apr 2;27(7)
Molecules (Basel, Switzerland) 2022 Apr 2;27(7)
The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors.
Liu W, Zhang B, Zhang D, Guo F, Ye K, Zhu L, Jin X
Cell death & disease 2022 Apr 2;13(4):295
Cell death & disease 2022 Apr 2;13(4):295
Indole alkaloids of Alstonia scholaris (L.) R. Br. alleviated nonalcoholic fatty liver disease in mice fed with high-fat diet.
Sun SF, Zhong HJ, Zhao YL, Ma XY, Luo JB, Zhu L, Zhang YT, Wang WX, Luo XD, Geng JW
Natural products and bioprospecting 2022 Apr 2;12(1):14
Natural products and bioprospecting 2022 Apr 2;12(1):14
Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
Božič J, Motaln H, Janež AP, Markič L, Tripathi P, Yamoah A, Aronica E, Lee YB, Heilig R, Fischer R, Thompson AJ, Goswami A, Rogelj B
Brain : a journal of neurology 2022 Apr 18;145(2):684-699
Brain : a journal of neurology 2022 Apr 18;145(2):684-699
Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation.
Hou M, Shao Z, Zhang S, Liu X, Fan P, Jiang M, Zhao Y, Xiao R, Yuan H
Cell death & disease 2022 Apr 18;13(4):362
Cell death & disease 2022 Apr 18;13(4):362
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Zeng HF, Xu J, Wang XL, Li SJ, Han ZY
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.
Zhao Y, Xue P, Lin G, Tong M, Yang J, Zhang Y, Ran K, Zhuge D, Yao Q, Xu H
Acta biomaterialia 2022 Apr 15;143:233-252
Acta biomaterialia 2022 Apr 15;143:233-252
A Single Amino Acid Residue R144 of SNX16 Affects Its Ability to Inhibit the Replication of Influenza A Virus.
Shi W, Jiang L, Ye M, Wang B, Chang Y, Shan Z, Wang X, Hu Y, Chen H, Li C
Viruses 2022 Apr 15;14(4)
Viruses 2022 Apr 15;14(4)
MFSD4A inhibits the malignant progression of nasopharyngeal carcinoma by targeting EPHA2.
Yang H, Qin G, Luo Z, Kong X, Gan C, Zhang R, Jiang W
Cell death & disease 2022 Apr 11;13(4):332
Cell death & disease 2022 Apr 11;13(4):332
Neurturin promotes tumor cell motility and angiogenesis in colorectal cancer.
Wang S, Nie L, Song Y, Zhang F, Chen X, Shi W, Yang Z, Sun Y, Dang Q, Gao A
Experimental cell research 2022 Apr 1;413(1):113049
Experimental cell research 2022 Apr 1;413(1):113049
CircSCAP interacts with SF3A3 to inhibit the malignance of non-small cell lung cancer by activating p53 signaling.
Chen D, Zhou H, Cai Z, Cai K, Liu J, Wang W, Miao H, Li H, Li R, Li X, Chen Y, Wang HY, Wen Z
Journal of experimental & clinical cancer research : CR 2022 Apr 1;41(1):120
Journal of experimental & clinical cancer research : CR 2022 Apr 1;41(1):120
Rho kinase inhibition ameliorates vascular remodeling and blood pressure elevations in a rat model of apatinib-induced hypertension.
Li C, Ma L, Wang Q, Shao X, Guo L, Chen J, Wang W, Yu J
Journal of hypertension 2022 Apr 1;40(4):675-684
Journal of hypertension 2022 Apr 1;40(4):675-684
Identification of a heterozygous variant of ZP2 as a novel cause of empty follicle syndrome in humans and mice.
Shen Y, Guo J, Zhang X, Wang X, Zhu S, Chen D, Xiong W, Lu G, Liu X, Dai C, Gong F, Wang Y, Lin G, Wang Z, Xu W
Human reproduction (Oxford, England) 2022 Apr 1;37(4):859-872
Human reproduction (Oxford, England) 2022 Apr 1;37(4):859-872
UBE2E3 regulates cellular senescence and osteogenic differentiation of BMSCs during aging.
Liu Y, Cai G, Chen P, Jiang T, Xia Z
PeerJ 2021;9:e12253
PeerJ 2021;9:e12253
Icaritin protects SH-SY5Y cells transfected with TDP-43 by alleviating mitochondrial damage and oxidative stress.
Zhou Y, Huang N, Li Y, Ba Z, Zhou Y, Luo Y
PeerJ 2021;9:e11978
PeerJ 2021;9:e11978
High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study.
Li P, Sun J, Ruan Y, Song L
PeerJ 2021;9:e11551
PeerJ 2021;9:e11551
NFIB promotes the migration and progression of kidney renal clear cell carcinoma by regulating PINK1 transcription.
Wang N, Yuan J, Liu F, Wei J, Liu Y, Xue M, Dong R
PeerJ 2021;9:e10848
PeerJ 2021;9:e10848
Role of GDNF, GFRα1 and GFAP in a Bifidobacterium-Intervention Induced Mouse Model of Intestinal Neuronal Dysplasia.
Liu W, Zhou T, Tian J, Yu X, Ren C, Cao Z, Hou P, Zhang Q, Li A
Frontiers in pediatrics 2021;9:795678
Frontiers in pediatrics 2021;9:795678
GLIS Family Zinc Finger 1 was First Linked With Preaxial Polydactyly I in Humans by Stepwise Genetic Analysis.
Jin JY, Wu PF, Luo FM, Guo BB, Zeng L, Fan LL, Tang JY, Xiang R
Frontiers in cell and developmental biology 2021;9:781388
Frontiers in cell and developmental biology 2021;9:781388
Estrogen Attenuates Chronic Stress-Induced Cardiomyopathy by Adaptively Regulating Macrophage Polarizations via β(2)-Adrenergic Receptor Modulation.
Hou H, Adzika GK, Wu Q, Ma T, Ma Y, Geng J, Shi M, Fu L, Rizvi R, Gong Z, Sun H
Frontiers in cell and developmental biology 2021;9:737003
Frontiers in cell and developmental biology 2021;9:737003
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adzraku SY, Li K, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, Shang W, Ma T, Koda S, Ma X, Sun H
Frontiers in cell and developmental biology 2021;9:719351
Frontiers in cell and developmental biology 2021;9:719351
SYMPK Is Required for Meiosis and Involved in Alternative Splicing in Male Germ Cells.
Wu R, Zhan J, Zheng B, Chen Z, Li J, Li C, Liu R, Zhang X, Huang X, Luo M
Frontiers in cell and developmental biology 2021;9:715733
Frontiers in cell and developmental biology 2021;9:715733
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
Meihe L, Shan G, Minchao K, Xiaoling W, Peng A, Xili W, Jin Z, Huimin D
Frontiers in cell and developmental biology 2021;9:707959
Frontiers in cell and developmental biology 2021;9:707959
LncRNA NEAT1 Promotes Gastric Cancer Progression Through miR-17-5p/TGFβR2 Axis Up-Regulated Angiogenesis.
Xu Y, Li Y, Qiu Y, Sun F, Zhu G, Sun J, Cai G, Lin W, Fu Y, Wu H, Jiang S, Wen Z, Feng F, Luo J, Yang Y, Zhang Q
Frontiers in cell and developmental biology 2021;9:705697
Frontiers in cell and developmental biology 2021;9:705697
IRE1-mTOR-PERK Axis Coordinates Autophagy and ER Stress-Apoptosis Induced by P2X7-Mediated Ca(2+) Influx in Osteoarthritis.
Li Z, Huang Z, Zhang H, Lu J, Wei Y, Yang Y, Bai L
Frontiers in cell and developmental biology 2021;9:695041
Frontiers in cell and developmental biology 2021;9:695041
NR2F1-AS1/miR-190a/PHLDB2 Induces the Epithelial-Mesenchymal Transformation Process in Gastric Cancer by Promoting Phosphorylation of AKT3.
Lv J, Zhang S, Liu Y, Li C, Guo T, Zhang S, Li Z, Jiao Z, Sun H, Zhang Y, Xu L
Frontiers in cell and developmental biology 2021;9:688949
Frontiers in cell and developmental biology 2021;9:688949
GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis.
Zhu HZ, Zhang LY, Zhai ME, Xia L, Cao Y, Xu L, Li KF, Jiang LQ, Shi H, Li X, Zhou YN, Ding W, Wang DX, Gao EH, Liu JC, Yu SQ, Duan WX
Frontiers in cell and developmental biology 2021;9:686848
Frontiers in cell and developmental biology 2021;9:686848
CircGNG4 Promotes the Progression of Prostate Cancer by Sponging miR-223 to Enhance EYA3/c-myc Expression.
Xu S, Lian Z, Zhang S, Xu Y, Zhang H
Frontiers in cell and developmental biology 2021;9:684125
Frontiers in cell and developmental biology 2021;9:684125
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
SMARCC1 Suppresses Tumor Progression by Inhibiting the PI3K/AKT Signaling Pathway in Prostate Cancer.
Xiao ZM, Lv DJ, Yu YZ, Wang C, Xie T, Wang T, Song XL, Zhao SC
Frontiers in cell and developmental biology 2021;9:678967
Frontiers in cell and developmental biology 2021;9:678967
PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks.
Tan YY, Zhang Y, Li B, Ou YW, Xie SJ, Chen PP, Mei SQ, Huang QJ, Zheng LL, Qu LH
Frontiers in cell and developmental biology 2021;9:670435
Frontiers in cell and developmental biology 2021;9:670435
Bhlhe40/Sirt1 Axis-Regulated Mitophagy Is Implicated in All-Trans Retinoic Acid-Induced Spina Bifida Aperta.
Zhao L, Liu D, Ma W, Gu H, Wei X, Luo W, Yuan Z
Frontiers in cell and developmental biology 2021;9:644346
Frontiers in cell and developmental biology 2021;9:644346
Tea Polyphenols Prevent Sepsis-Induced Lung Injury via Promoting Translocation of DJ-1 to Mitochondria.
Jia CM, Zhang FW, Wang SJ, Wang W, Li Y
Frontiers in cell and developmental biology 2021;9:622507
Frontiers in cell and developmental biology 2021;9:622507
Schwann Cell-Derived Exosomes Induce the Differentiation of Human Adipose-Derived Stem Cells Into Schwann Cells.
Zhou N, Xu Z, Li X, Ren S, Chen J, Xiong H, Wang C, Guo J, Kang Y, Chen Z, Li W, Yang X, Zhang X, Xu X
Frontiers in molecular biosciences 2021;8:835135
Frontiers in molecular biosciences 2021;8:835135
MCC Regulator of WNT Signaling Pathway (MCC) Is a Podocyte Essential Gene.
Song H, Zhuang L, Xu X, Shi J, Hu W, Liu Z, Shi S
Frontiers in medicine 2021;8:777563
Frontiers in medicine 2021;8:777563
Sodium-Glucose Co-transporter-2 Inhibitor of Dapagliflozin Attenuates Myocardial Ischemia/Reperfusion Injury by Limiting NLRP3 Inflammasome Activation and Modulating Autophagy.
Yu YW, Que JQ, Liu S, Huang KY, Qian L, Weng YB, Rong FN, Wang L, Zhou YY, Xue YJ, Ji KT
Frontiers in cardiovascular medicine 2021;8:768214
Frontiers in cardiovascular medicine 2021;8:768214
Establishment of a Dihydrofolate Reductase Gene Knock-In Zebrafish Strain to Aid Preliminary Analysis of Congenital Heart Disease Mechanisms.
Gong K, Xie T, Yang Y, Luo Y, Deng Y, Chen K, Tan Z, Guo H, Xie L
Frontiers in cardiovascular medicine 2021;8:763851
Frontiers in cardiovascular medicine 2021;8:763851
Caspase-1 Inhibitor Reduces Pyroptosis Induced by Brain Death in Kidney.
Liu W, Yang D, Shi J, Wen P, Zhang J, Wang Z, Hu B, Shi X, Cao S, Guo W, Zhang S
Frontiers in surgery 2021;8:760989
Frontiers in surgery 2021;8:760989
Chromatin-Associated Protein Sugp2 Involved in mRNA Alternative Splicing During Mouse Spermatogenesis.
Zhan J, Li J, Wu Y, Wu P, Yu Z, Cui P, Zhou M, Xu Y, Jin T, Du Z, Luo M, Liu C
Frontiers in veterinary science 2021;8:754021
Frontiers in veterinary science 2021;8:754021
Isoproterenol-Induced Cardiomyopathy Recovery Intervention: Amlexanox and Forskolin Enhances the Resolution of Catecholamine Stress-Induced Maladaptive Myocardial Remodeling.
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adu-Amankwaah J, Shang W, Li K, Deng QM, Mprah R, Ndzie Noah ML, Sun H
Frontiers in cardiovascular medicine 2021;8:719805
Frontiers in cardiovascular medicine 2021;8:719805
Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway.
Jiao W, Bai M, Yin H, Liu J, Sun J, Su X, Zeng H, Wen J
Frontiers in molecular biosciences 2021;8:690170
Frontiers in molecular biosciences 2021;8:690170
Taurine Protects C2C12 Myoblasts From Impaired Cell Proliferation and Myotube Differentiation Under Cisplatin-Induced ROS Exposure.
Zhou L, Lu R, Huang C, Lin D
Frontiers in molecular biosciences 2021;8:685362
Frontiers in molecular biosciences 2021;8:685362
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.
Yang W, Feng Q, Li M, Su J, Wang P, Wang X, Yin Y, Wang X, Zhao M
Frontiers in molecular biosciences 2021;8:684262
Frontiers in molecular biosciences 2021;8:684262
Inhibition of Peptidyl Arginine Deiminase 4-Dependent Neutrophil Extracellular Trap Formation Reduces Angiotensin II-Induced Abdominal Aortic Aneurysm Rupture in Mice.
Wei M, Wang X, Song Y, Zhu D, Qi D, Jiao S, Xie G, Liu Y, Yu B, Du J, Wang Y, Qu A
Frontiers in cardiovascular medicine 2021;8:676612
Frontiers in cardiovascular medicine 2021;8:676612
Pilose Antler Peptide-3.2KD Ameliorates Adriamycin-Induced Myocardial Injury Through TGF-β/SMAD Signaling Pathway.
Xu Y, Qu X, Zhou J, Lv G, Han D, Liu J, Liu Y, Chen Y, Qu P, Huang X
Frontiers in cardiovascular medicine 2021;8:659643
Frontiers in cardiovascular medicine 2021;8:659643
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Li X, Gao M, Zhu S, Yin L, Zhang B, Qi Y, Zhao Y, Yu Y, Xu L
Frontiers in nutrition 2021;8:635232
Frontiers in nutrition 2021;8:635232
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Xie X, Chen C, Feng S, Zuo S, Zhao X, Li H
Journal of hepatocellular carcinoma 2021;8:1623-1641
Journal of hepatocellular carcinoma 2021;8:1623-1641
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167
Nutrition and cancer 2021;73(7):1157-1167
Renal NKCC2 Is Dual Regulated by the Synergy of 20-HETE and High-Fat Diet in CYP4F2 Transgenic Mice.
Wu J, Lai G, Chen F, Zhang B, Zhao Y
Kidney & blood pressure research 2021;46(5):601-612
Kidney & blood pressure research 2021;46(5):601-612
Molecular mechanism of dihydropyrazine-induced cytotoxicity: the possibility of an independent pathway from the receptor for advanced glycation end products.
Miyauchi Y, Sawai M, Ishida T, Kansui H, Takechi S
The Journal of toxicological sciences 2021;46(11):509-514
The Journal of toxicological sciences 2021;46(11):509-514
KCNN4 promotes the progression of lung adenocarcinoma by activating the AKT and ERK signaling pathways.
Xu P, Mo X, Xia R, Jiang L, Zhang C, Xu H, Sun Q, Zhou G, Zhang Y, Wang Y, Xia H
Cancer biomarkers : section A of Disease markers 2021;31(2):187-201
Cancer biomarkers : section A of Disease markers 2021;31(2):187-201
Contribution of Growth Arrest-Specific 5/miR-674 to the Hypothalamus Pituitary Adrenal Axis Regulation Effect by Electroacupuncture following Trauma.
Zhu J, Guo C, Lu P, Shao S, Tu B
Neuroimmunomodulation 2021;28(3):137-149
Neuroimmunomodulation 2021;28(3):137-149
Comparative proteome analysis of form-deprivation myopia in sclera with iTRAQ-based quantitative proteomics.
Yuan Y, Zhu C, Liu M, Ke B
Molecular vision 2021;27:494-505
Molecular vision 2021;27:494-505
Analysis of Key Distinct Biological Characteristics of Human Placenta-Derived Mesenchymal Stromal Cells and Individual Heterogeneity Attributing to Donors.
Tai C, Wang L, Xie Y, Gao T, Huang F, Wang B
Cells, tissues, organs 2021;210(1):45-57
Cells, tissues, organs 2021;210(1):45-57
Nucleolin Promotes Cisplatin Resistance in Cervical Cancer by the YB1-MDR1 Pathway.
Ke J, Gu C, Zhang H, Liu Y, Zhang W, Rao H, Li S, Wu F
Journal of oncology 2021;2021:9992218
Journal of oncology 2021;2021:9992218
Protective Role of 4-Octyl Itaconate in Murine LPS/D-GalN-Induced Acute Liver Failure via Inhibiting Inflammation, Oxidative Stress, and Apoptosis.
Li R, Yang W, Yin Y, Zhang P, Wang Y, Tao K
Oxidative medicine and cellular longevity 2021;2021:9932099
Oxidative medicine and cellular longevity 2021;2021:9932099
Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation.
Ding R, Jiao L, Sang S, Yin Y, Wang Y, Gong Y, Xu L, Bi L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9930082
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9930082
Escin Sodium Improves the Prognosis of Acute Pancreatitis via Promoting Cell Apoptosis by Suppression of the ERK/STAT3 Signaling Pathway.
Zhang Q, Zhao C, Zhang L, Sun K, Yu L, Wang X, Ren L, Zhang N, Chen C, Liu J, Wang H, Tian H
Oxidative medicine and cellular longevity 2021;2021:9921839
Oxidative medicine and cellular longevity 2021;2021:9921839
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury.
Dou Q, Tong H, Yang Y, Zhang H, Gan H
BioMed research international 2021;2021:9884297
BioMed research international 2021;2021:9884297
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Wang B, Ke W, Wang K, Li G, Ma L, Lu S, Xiang Q, Liao Z, Luo R, Song Y, Hua W, Wu X, Zhang Y, Zeng X, Yang C
Oxidative medicine and cellular longevity 2021;2021:8884922
Oxidative medicine and cellular longevity 2021;2021:8884922
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Zhang Y, Chen G, Zhuang X, Guo M
Oxidative medicine and cellular longevity 2021;2021:8807676
Oxidative medicine and cellular longevity 2021;2021:8807676
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
Liu T, Xu P, Qi S, Ke S, Hu Q, Zhao P, Li J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity.
Song S, Li R, Cao B, Zhang J, Kim Y, Kim B, Yu X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8631475
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8631475
Paeoniflorin Protects against ANIT-Induced Cholestatic Liver Injury in Rats via the Activation of SIRT1-FXR Signaling Pathway.
Chen L, Wei S, Liu H, Li J, Jing M, Tong Y, Li R, Wen J, Zhan H, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8479868
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8479868
GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation.
Xu Y, Hu X, Li F, Zhang H, Lou J, Wang X, Wang H, Yin L, Ni W, Kong J, Wang X, Li Y, Zhou K, Xu H
Oxidative medicine and cellular longevity 2021;2021:8186877
Oxidative medicine and cellular longevity 2021;2021:8186877
lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis.
Wang SZ, Jia J, Chen CH
Stem cells international 2021;2021:7690006
Stem cells international 2021;2021:7690006
Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene.
Huo S, Shi W, Ma H, Yan D, Luo P, Guo J, Li C, Lin J, Zhang C, Li S, Lv J, Lin L
Oxidative medicine and cellular longevity 2021;2021:6699054
Oxidative medicine and cellular longevity 2021;2021:6699054
Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration.
Hu S, Zhang C, Qian T, Bai Y, Chen L, Chen J, Huang C, Xie C, Wang X, Jin H
Oxidative medicine and cellular longevity 2021;2021:6694964
Oxidative medicine and cellular longevity 2021;2021:6694964
TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38(-/-) Sepsis Mice.
Zhang H, Du Y, Guo Y, Wang Z, Li H, Lv Z, Zeng L, Chen Y, Xie Z, Li R
Journal of immunology research 2021;2021:6687555
Journal of immunology research 2021;2021:6687555
High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.
Pi T, Wei S, Jiang Y, Shi JS
Behavioural neurology 2021;2021:6683318
Behavioural neurology 2021;2021:6683318
ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling.
Tang J, Fang K, Li C, Chang X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6683264
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6683264
Tilianin Ameliorates Cognitive Dysfunction and Neuronal Damage in Rats with Vascular Dementia via p-CaMKII/ERK/CREB and ox-CaMKII-Dependent MAPK/NF-κB Pathways.
Jiang H, Ashraf GM, Liu M, Zhao K, Wang Y, Wang L, Xing J, Alghamdi BS, Li Z, Liu R
Oxidative medicine and cellular longevity 2021;2021:6673967
Oxidative medicine and cellular longevity 2021;2021:6673967
Follistatin-Like 1 Attenuation Suppresses Intervertebral Disc Degeneration in Mice through Interacting with TNF-α and Smad Signaling Pathway.
Wang S, Wei J, Shi J, He Q, Zhou X, Gao X, Cheng L
Oxidative medicine and cellular longevity 2021;2021:6640751
Oxidative medicine and cellular longevity 2021;2021:6640751
Electroacupuncture Inhibits Autophagy of Neuron Cells in Postherpetic Neuralgia by Increasing the Expression of miR-223-3p.
Zou J, Dong X, Wang K, Shi J, Sun N
BioMed research international 2021;2021:6637693
BioMed research international 2021;2021:6637693
Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway.
Yu H, Hou G, Cao J, Yin Y, Zhao Y, Cheng L
Oxidative medicine and cellular longevity 2021;2021:6632786
Oxidative medicine and cellular longevity 2021;2021:6632786
Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy.
Zhang S, Liang W, Abulizi Y, Xu T, Cao R, Xun C, Zhang J, Sheng W
BioMed research international 2021;2021:6631562
BioMed research international 2021;2021:6631562
Glucagon-like Peptide-1 Improves Fatty Liver and Enhances Thermogenesis in Brown Adipose Tissue via Inhibiting BMP4-Related Signaling Pathway in High-Fat-Diet-Induced Obese Mice.
Wang X, Ma B, Chen J, You H, Sheng C, Yang P, Qu S
International journal of endocrinology 2021;2021:6620289
International journal of endocrinology 2021;2021:6620289
Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway.
Wang Y, Bai B, Hu Y, Wang H, Liu N, Li Y, Li P, Zhou G, Zhou Q
Stem cells international 2021;2021:5626487
Stem cells international 2021;2021:5626487
FTZ Ameliorates Diabetic Cardiomyopathy by Inhibiting Inflammation and Cardiac Fibrosis in the Streptozotocin-Induced Model.
Wang L, Wu H, Deng Y, Zhang S, Wei Q, Yang Q, Piao S, Bei W, Rong X, Guo J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582567
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582567
Pharmic Activation of PKG2 Alleviates Diabetes-Induced Osteoblast Dysfunction by Suppressing PLCβ1-Ca(2+)-Mediated Endoplasmic Reticulum Stress.
Jia T, Wang YN, Feng Y, Wang C, Zhang D, Xu X
Oxidative medicine and cellular longevity 2021;2021:5552530
Oxidative medicine and cellular longevity 2021;2021:5552530
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
Su X, Yang Y, Guo C, Zhang R, Sun S, Wang Y, Qiao Q, Fu Y, Pang Q
Oxidative medicine and cellular longevity 2021;2021:5549047
Oxidative medicine and cellular longevity 2021;2021:5549047
UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway.
Yang Z, Li H, Luo P, Yan D, Yang N, Zhang Y, Huang Y, Liu Y, Zhang L, Yan J, Zhang C
Oxidative medicine and cellular longevity 2021;2021:5546711
Oxidative medicine and cellular longevity 2021;2021:5546711
Shen Shuai II Recipe Attenuates Renal Interstitial Fibrosis by Improving Hypoxia via the IL-1β/c-Myc Pathway.
Yang L, Wang M, Zhou Y, Yang J, Ye C, Wang C
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5539584
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5539584
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Wan Y, Song M, Xie X, Chen Z, Gao Z, Wu X, Huang R, Chen M
Mediators of inflammation 2021;2021:5522291
Mediators of inflammation 2021;2021:5522291
miR-381-3p Involves in Glioma Progression by Suppressing Tumor-Promoter Factor ANTXR1.
Dong Z, Zhang J, Niu L, Hou G, Gao Z, Yang Q
Computational and mathematical methods in medicine 2021;2021:4883509
Computational and mathematical methods in medicine 2021;2021:4883509
YQHX Alleviates H/R-Induced Cardiomyocyte Apoptosis by Downregulating miR-1.
Ge L, Fan Y, Fu L, Guo M, Cao P, Peng C, Wu L, Han L, Wu H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4852406
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4852406
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Wu R, Jian T, Ding X, Lv H, Meng X, Ren B, Li J, Chen J, Li W
Oxidative medicine and cellular longevity 2021;2021:4706410
Oxidative medicine and cellular longevity 2021;2021:4706410
Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways.
Che X, Zhan J, Zhao F, Zhong Z, Chen M, Han R, Wang Y
BioMed research international 2021;2021:4340950
BioMed research international 2021;2021:4340950
ARHGAP11A Promotes the Malignant Progression of Gastric Cancer by Regulating the Stability of Actin Filaments through TPM1.
Guan X, Guan X, Qin J, Qin L, Shi W, Jiao Z
Journal of oncology 2021;2021:4146910
Journal of oncology 2021;2021:4146910
miR-19a-3p Promotes Tumor-Relevant Behaviors in Bladder Urothelial Carcinoma via Targeting THBS1.
Xu G, Li J, Yu L
Computational and mathematical methods in medicine 2021;2021:2710231
Computational and mathematical methods in medicine 2021;2021:2710231
Huanglian Jiedu Decoction Exerts Antipyretic Effect by Inhibiting MAPK Signaling Pathway.
Li X, Wei S, Ma X, Li H, Jing M, Liu H, Niu S, Tong Y, Chen L, Wei Y, Ren S, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2209574
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2209574
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
Xin Y, Shang X, Sun X, Liu Y, Xu G, Xue G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells.
Li ZX, Wang LX, Zhang Y, Chen W, Zeng YQ
BioMed research international 2021;2021:1086206
BioMed research international 2021;2021:1086206
PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosis.
Du P, Luo K, Li G, Zhu J, Xiao Q, Li Y, Zhang X
International journal of medical sciences 2021;18(15):3588-3598
International journal of medical sciences 2021;18(15):3588-3598
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway.
Ke J, Zhao F, Luo Y, Deng F, Wu X
International journal of biological sciences 2021;17(8):2099-2111
International journal of biological sciences 2021;17(8):2099-2111
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Bai R, Yuan C, Sun W, Zhang J, Luo Y, Gao Y, Li Y, Gong Y, Xie C
International journal of biological sciences 2021;17(8):1995-2008
International journal of biological sciences 2021;17(8):1995-2008
UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185.
Zheng Z, Zhang B, Yu H, Li S, Song N, Jin X, Li J
International journal of biological sciences 2021;17(12):3024-3035
International journal of biological sciences 2021;17(12):3024-3035
SEC23A Inhibit Melanoma Metastatic through Secretory PF4 Cooperation with SPARC to Inhibit MAPK Signaling Pathway.
Zeng B, Sun Z, Zhao Q, Liu D, Chen H, Li X, Xing HR, Wang J
International journal of biological sciences 2021;17(12):3000-3012
International journal of biological sciences 2021;17(12):3000-3012
ACE2 Correlated With Immune Infiltration Serves As A Novel Prognostic Biomarker In Clear Cell Renal Cell Carcinoma: Implication For COVID-19.
Yang W, Li L, Zhang K, Ma K, Xie H, Gong Y, Zhou J, Gong K
International journal of biological sciences 2021;17(1):20-31
International journal of biological sciences 2021;17(1):20-31
Vagal Nerve Stimulation Protects Against Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis.
Zhang LN, Zhang XW, Li CQ, Guo J, Chen YP, Chen SL
Neuropsychiatric disease and treatment 2021;17:905-913
Neuropsychiatric disease and treatment 2021;17:905-913
LINC00958 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of oesophageal squamous cell carcinoma cells.
Wang B, Tang D, Liu Z, Wang Q, Xue S, Zhao Z, Feng D, Sheng C, Li J, Zhou Z
PloS one 2021;16(5):e0251797
PloS one 2021;16(5):e0251797
Bioinformatics analysis for the role of CALR in human cancers.
Li Y, Liu X, Chen H, Xie P, Ma R, He J, Zhang H
PloS one 2021;16(12):e0261254
PloS one 2021;16(12):e0261254
Prognostic role of oxytocin receptor in colon adenocarcinoma.
Sun J, Xu Z, Mao Y, Zhang T, Qin Y, Hua D
Open medicine (Warsaw, Poland) 2021;16(1):1762-1776
Open medicine (Warsaw, Poland) 2021;16(1):1762-1776
Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Sui M, Xiong M, Li Y, Zhou Q, Shen X, Jia D, Gou M, Sun Q
International journal of nanomedicine 2021;16:2833-2847
International journal of nanomedicine 2021;16:2833-2847
Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species.
Dou J, Li L, Guo M, Mei F, Zheng D, Xu H, Xue R, Bao X, Zhao F, Zhang Y
International journal of nanomedicine 2021;16:1231-1244
International journal of nanomedicine 2021;16:1231-1244
Expression of the ACE2 Virus Entry Protein in the Nervus Terminalis Reveals the Potential for an Alternative Route to Brain Infection in COVID-19.
Bilinska K, von Bartheld CS, Butowt R
Frontiers in cellular neuroscience 2021;15:674123
Frontiers in cellular neuroscience 2021;15:674123
Gut Microbial Metabolite Short-Chain Fatt Acids Partially Reverse Surgery and Anesthesia-Induced Behavior Deficits in C57BL/6J Mice.
Xu X, Wang K, Cao X, Li Z, Zhou Y, Ren J, Liu F
Frontiers in neuroscience 2021;15:664641
Frontiers in neuroscience 2021;15:664641
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
Xing Y, Zhang M, Wang MM, Feng YS, Dong F, Zhang F
Frontiers in cellular neuroscience 2021;15:633280
Frontiers in cellular neuroscience 2021;15:633280
High-Dose Dexmedetomidine Promotes Apoptosis in Fetal Rat Hippocampal Neurons.
Wei Q, Chen J, Xiao F, Tu Y, Zhong Y, Xie Y
Drug design, development and therapy 2021;15:2433-2444
Drug design, development and therapy 2021;15:2433-2444
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
Yang Y, Yi J, Pan M, Hu B, Duan H
Drug design, development and therapy 2021;15:1409-1422
Drug design, development and therapy 2021;15:1409-1422
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Luo W, Yang Z, Zhang W, Zhou D, Guo X, Wang S, He F, Wang Y
Frontiers in molecular neuroscience 2021;14:785938
Frontiers in molecular neuroscience 2021;14:785938
Aberrant Fluid Shear Stress Contributes to Articular Cartilage Pathogenesis via Epigenetic Regulation of ZBTB20 by H3K4me3.
Jin Y, Li Z, Wu Y, Li H, Liu Z, Liu L, Ouyang N, Zhou T, Fang B, Xia L
Journal of inflammation research 2021;14:6067-6083
Journal of inflammation research 2021;14:6067-6083
Effects of UV Induced-Photoaging on the Hair Follicle Cycle of C57BL6/J Mice.
Zhai X, Gong M, Peng Y, Yang D
Clinical, cosmetic and investigational dermatology 2021;14:527-539
Clinical, cosmetic and investigational dermatology 2021;14:527-539
ILT4 in Colorectal Cancer Cells Induces Suppressive T Cell Contexture and Disease Progression.
Yang Z, Gao A, Shi W, Wang J, Zhang X, Xu Z, Xu T, Zheng Y, Sun Y, Yang F
OncoTargets and therapy 2021;14:4239-4254
OncoTargets and therapy 2021;14:4239-4254
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J
Journal of inflammation research 2021;14:3489-3500
Journal of inflammation research 2021;14:3489-3500
The ALDOA Metabolism Pathway as a Potential Target for Regulation of Prostate Cancer Proliferation.
Kuang Q, Liang Y, Zhuo Y, Cai Z, Jiang F, Xie J, Zheng Y, Zhong W
OncoTargets and therapy 2021;14:3353-3366
OncoTargets and therapy 2021;14:3353-3366
Store-Operated Calcium Channels Contribute to Remifentanil-Induced Postoperative Hyperalgesia via Phosphorylation of CaMKIIα in Rats.
Zhou Z, Mao M, Cai X, Zhu W, Sun J
Journal of pain research 2021;14:3289-3299
Journal of pain research 2021;14:3289-3299
Downregulation of TAF9B by miR-7-5p Inhibits the Progression of Osteosarcoma.
Gu W, Chen P, Ren P, Wang Y, Li X, Gong M
OncoTargets and therapy 2021;14:2917-2927
OncoTargets and therapy 2021;14:2917-2927
MicroRNA-302s Might Regulate ARL4C-Mediated Gastric Cancer Progression via p53 Signaling: Bioinformatics Analysis and Experiments Validation.
Xie N, Pan Y, Wu J, Bai Y, Xiao C, Gao X, Wang J, Liu N
OncoTargets and therapy 2021;14:2541-2553
OncoTargets and therapy 2021;14:2541-2553
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and therapy 2021;14:2339-2348
OncoTargets and therapy 2021;14:2339-2348
ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes.
Li RZ, Li YY, Qin H, Li SS
OncoTargets and therapy 2021;14:199-211
OncoTargets and therapy 2021;14:199-211
Prognostic Value and Biological Functions of RNA Binding Proteins in Stomach Adenocarcinoma.
Li J, Zhou W, Wei J, Xiao X, An T, Wu W, He Y
OncoTargets and therapy 2021;14:1689-1705
OncoTargets and therapy 2021;14:1689-1705
Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study.
Hu X, Li R, Sun M, Kong Y, Zhu H, Wang F, Wan Q
Journal of inflammation research 2021;14:1403-1414
Journal of inflammation research 2021;14:1403-1414
Hydrogen (H(2)) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway.
Lu H, Wang W, Kang X, Lin Z, Pan J, Cheng S, Zhang J
Journal of inflammation research 2021;14:1387-1402
Journal of inflammation research 2021;14:1387-1402
MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats.
Feng X, Hu J, Zhan F, Luo D, Hua F, Xu G
Journal of inflammation research 2021;14:1125-1143
Journal of inflammation research 2021;14:1125-1143
Ulinastatin protects against acetaminophen-induced liver injury by alleviating ferroptosis via the SIRT1/NRF2/HO-1 pathway.
Wang C, Liu T, Tong Y, Cui R, Qu K, Liu C, Zhang J
American journal of translational research 2021;13(6):6031-6042
American journal of translational research 2021;13(6):6031-6042
Nox2 contributes to reactive oxygen species-induced redox imbalance in cancer-induced bone pain.
Xu BY, Sun J, Chen SP, Wang XM, Chen N, Li DY, Chen G, Mei W, Tian YK, Zhou YQ, Ye DW
American journal of translational research 2021;13(3):1269-1279
American journal of translational research 2021;13(3):1269-1279
Analysis of m6A-Related lncRNAs for Prognosis Value and Response to Immune Checkpoint Inhibitors Therapy in Hepatocellular Carcinoma.
Wang Y, Li N, Tian D, Zhou CW, Wang YH, Yang C, Zeng MS
Cancer management and research 2021;13:6451-6471
Cancer management and research 2021;13:6451-6471
Circ_0006174 Accelerates Colorectal Cancer Progression Through Regulating miR-138-5p/MACC1 Axis.
Wei J, Lin Y, Wang Z, Liu Y, Guo W
Cancer management and research 2021;13:1673-1686
Cancer management and research 2021;13:1673-1686
LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process.
Sun Z, Shao B, Liu Z, Dang Q, Guo Y, Chen C, Guo Y, Chen Z, Liu J, Hu S, Yuan W, Zhou Q
Journal of Cancer 2021;12(9):2723-2734
Journal of Cancer 2021;12(9):2723-2734
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Wang L, Huang Y, Liu C, Guo M, Ma Z, He J, Wang A, Sun X, Liu Z
Journal of Cancer 2021;12(3):860-873
Journal of Cancer 2021;12(3):860-873
Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway.
Zhang J, Li P, Li T, Zhou Z, Wu H, Zhang L
Journal of Cancer 2021;12(24):7465-7476
Journal of Cancer 2021;12(24):7465-7476
RNA-binding Protein MBNL2 regulates Cancer Cell Metastasis through MiR-182-MBNL2-AKT Pathway.
Lin G, Li J, Cai J, Zhang H, Xin Q, Wang N, Xie W, Zhang Y, Xu N
Journal of Cancer 2021;12(22):6715-6726
Journal of Cancer 2021;12(22):6715-6726
BZW2/5MP1 acts as a promising target in hepatocellular carcinoma.
Li G, Lu A, Chen A, Geng S, Xu Y, Chen X, Yang J
Journal of Cancer 2021;12(17):5125-5135
Journal of Cancer 2021;12(17):5125-5135
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697
Journal of Cancer 2021;12(15):4686-4697
Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p.
Qian J, Xu Y, Xu X, Tao Z, Luo Y, Xu Y, Zhang Y, Qian C
Journal of Cancer 2021;12(11):3249-3256
Journal of Cancer 2021;12(11):3249-3256
HnRNP-F promotes the proliferation of bladder cancer cells mediated by PI3K/AKT/FOXO1.
Li F, Xie W, Fang Y, Xie K, Liu W, Hou L, Tan W
Journal of Cancer 2021;12(1):281-291
Journal of Cancer 2021;12(1):281-291
A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway.
Cao HJ, Zhou W, Xian XL, Sun SJ, Ding PJ, Tian CY, Tian FL, Jiang CH, Fu TT, Zhao S, Dai JY
Frontiers in pharmacology 2021;12:821485
Frontiers in pharmacology 2021;12:821485
Cordyceps cicadae Ameliorates Renal Hypertensive Injury and Fibrosis Through the Regulation of SIRT1-Mediated Autophagy.
Cai Y, Feng Z, Jia Q, Guo J, Zhang P, Zhao Q, Wang YX, Liu YN, Liu WJ
Frontiers in pharmacology 2021;12:801094
Frontiers in pharmacology 2021;12:801094
Shenkang Injection and Its Three Anthraquinones Ameliorates Renal Fibrosis by Simultaneous Targeting IƙB/NF-ƙB and Keap1/Nrf2 Signaling Pathways.
Luo LP, Suo P, Ren LL, Liu HJ, Zhang Y, Zhao YY
Frontiers in pharmacology 2021;12:800522
Frontiers in pharmacology 2021;12:800522
Cang-Ai Volatile Oil Ameliorates Depressive Behavior Induced by Chronic Stress Through IDO-Mediated Tryptophan Degradation Pathway.
Zhang K, Lei N, Li M, Li J, Li C, Shen Y, Guo P, Xiong L, Xie Y
Frontiers in psychiatry 2021;12:791991
Frontiers in psychiatry 2021;12:791991
HOTAIR Up-Regulation Activates NF-κB to Induce Immunoescape in Gliomas.
Wang Y, Yi K, Liu X, Tan Y, Jin W, Li Y, Zhou J, Wang H, Kang C
Frontiers in immunology 2021;12:785463
Frontiers in immunology 2021;12:785463
Melatonin Mitigates Oxazolone-Induced Colitis in Microbiota-Dependent Manner.
Zhao ZX, Yuan X, Cui YY, Liu J, Shen J, Jin BY, Feng BC, Zhai YJ, Zheng MQ, Kou GJ, Zhou RC, Li LX, Zuo XL, Li SY, Li YQ
Frontiers in immunology 2021;12:783806
Frontiers in immunology 2021;12:783806
The Zebrafish Antiapoptotic Protein BIRC2 Promotes Edwardsiella piscicida Infection by Inhibiting Caspases and Accumulating p53 in a p53 Transcription-Dependent and -Independent Manner.
Cao L, Yan D, Xiao J, Feng H, Chang MX
Frontiers in immunology 2021;12:781680
Frontiers in immunology 2021;12:781680
Herb-Drug Interaction Between Xiyanping Injection and Lopinavir/Ritonavir, Two Agents Used in COVID-19 Pharmacotherapy.
Ye L, Cheng L, Deng Y, Liu H, Wu X, Wang T, Chang Q, Zhang Y, Wang D, Li Z, Yang X
Frontiers in pharmacology 2021;12:773126
Frontiers in pharmacology 2021;12:773126
The Role of Estrogen Receptor α in Response to Longitudinal Bone Growth in ob/ob Mice.
Jin LY, Guo C, Xu S, Liu HY, Li XF
Frontiers in endocrinology 2021;12:749449
Frontiers in endocrinology 2021;12:749449
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Yu HX, Lin W, Yang K, Wei LJ, Chen JL, Liu XY, Zhong K, Chen X, Pei M, Yang HT
Frontiers in pharmacology 2021;12:741801
Frontiers in pharmacology 2021;12:741801
Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT.
Zheng YW, Miao XY, Xiong L, Chen B, Kong FH, Zhou JJ, Liu ZT, Wen Y, Zhang ZJ, Zou H
Frontiers in pharmacology 2021;12:723488
Frontiers in pharmacology 2021;12:723488
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Su W, Feng M, Liu Y, Cao R, Liu Y, Tang J, Pan K, Lan R, Mao Z
Frontiers in pharmacology 2021;12:721471
Frontiers in pharmacology 2021;12:721471
Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway.
Jia Z, Wang K, Zhang Y, Duan Y, Xiao K, Liu S, Ding X
Frontiers in pharmacology 2021;12:720387
Frontiers in pharmacology 2021;12:720387
PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma.
Song Q, Zheng Y, Wu J, Wang S, Meng L, Yao Q, Li Z, Lian S
Frontiers in immunology 2021;12:717688
Frontiers in immunology 2021;12:717688
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Zhang S, Ding J, Wang J, Yin T, Zhang Y, Yang J
Frontiers in immunology 2021;12:717483
Frontiers in immunology 2021;12:717483
Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis.
Chen LJ, He JT, Pan M, Liu JL, Zhang KK, Li JH, Wang LB, Xu LL, Chen YK, Zhang QY, Li DR, Xu JT, Xie XL
Frontiers in pharmacology 2021;12:716703
Frontiers in pharmacology 2021;12:716703
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Yang W, Su J, Li M, Li T, Wang X, Zhao M, Hu X
Frontiers in pharmacology 2021;12:709526
Frontiers in pharmacology 2021;12:709526
Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3'UTR in Gastric Cancer Cells.
Shi X, Ding K, Zhao Q, Li P, Kang Y, Tan S, Sun J
Frontiers in genetics 2021;12:707644
Frontiers in genetics 2021;12:707644
Pimpinellin Inhibits Collagen-induced Platelet Aggregation and Activation Through Inhibiting Granule Secretion and PI3K/Akt Pathway.
Liu G, Yuan Z, Tian X, Xiong X, Guo F, Lin Z, Qin Z
Frontiers in pharmacology 2021;12:706363
Frontiers in pharmacology 2021;12:706363
Clemastine Fumarate Attenuates Myocardial Ischemia Reperfusion Injury Through Inhibition of Mast Cell Degranulation.
Meng S, Sun X, Juan Z, Wang M, Wang R, Sun L, Li Y, Xin A, Li S, Li Y
Frontiers in pharmacology 2021;12:704852
Frontiers in pharmacology 2021;12:704852
Reynoutrin Improves Ischemic Heart Failure in Rats Via Targeting S100A1.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in pharmacology 2021;12:703962
Frontiers in pharmacology 2021;12:703962
Neuropathic Injury-Induced Plasticity of GABAergic System in Peripheral Sensory Ganglia.
Wang C, Hao H, He K, An Y, Pu Z, Gamper N, Zhang H, Du X
Frontiers in pharmacology 2021;12:702218
Frontiers in pharmacology 2021;12:702218
Function of Chick Subcutaneous Adipose Tissue During the Embryonic and Posthatch Period.
Zhao H, Wu M, Tang X, Li Q, Yi X, Wang S, Jia C, Wei Z, Sun X
Frontiers in physiology 2021;12:684426
Frontiers in physiology 2021;12:684426
Salidroside Inhibits CCl(4)-Induced Liver Fibrosis in Mice by Reducing Activation and Migration of HSC Induced by Liver Sinusoidal Endothelial Cell-Derived Exosomal SphK1.
Ye Q, Zhou Y, Zhao C, Xu L, Ping J
Frontiers in pharmacology 2021;12:677810
Frontiers in pharmacology 2021;12:677810
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
Chen P, Wen Z, Shi W, Li Z, Chen X, Gao Y, Xu S, Gong Q, Deng J
Frontiers in pharmacology 2021;12:674570
Frontiers in pharmacology 2021;12:674570
The Application of Functional Magnetic Resonance Imaging in Type 2 Diabetes Rats With Contrast-Induced Acute Kidney Injury and the Associated Innate Immune Response.
Li Y, Shi D, Zhang H, Yao X, Wang S, Wang R, Ren K
Frontiers in physiology 2021;12:669581
Frontiers in physiology 2021;12:669581
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Ye R, Wang C, Sun P, Bai S, Zhao L
Frontiers in pharmacology 2021;12:669403
Frontiers in pharmacology 2021;12:669403
Downregulated MicroRNA-327 Attenuates Oxidative Stress-Mediated Myocardial Ischemia Reperfusion Injury Through Regulating the FGF10/Akt/Nrf2 Signaling Pathway.
Zheng T, Yang J, Zhang J, Yang C, Fan Z, Li Q, Zhai Y, Liu H, Yang J
Frontiers in pharmacology 2021;12:669146
Frontiers in pharmacology 2021;12:669146
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
Zhou F, Zhang X, Jiang L, Li S, Chen Y, Wu J
Frontiers in pharmacology 2021;12:667524
Frontiers in pharmacology 2021;12:667524
Synergic Neuroprotection Between Ligusticum Chuanxiong Hort and Borneol Against Ischemic Stroke by Neurogenesis via Modulating Reactive Astrogliosis and Maintaining the Blood-Brain Barrier.
Yu B, Yao Y, Zhang X, Ruan M, Zhang Z, Xu L, Liang T, Lu J
Frontiers in pharmacology 2021;12:666790
Frontiers in pharmacology 2021;12:666790
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Liu Y, Fu X, Chen Z, Luo T, Zhu C, Ji Y, Bian Z
Frontiers in pharmacology 2021;12:665894
Frontiers in pharmacology 2021;12:665894
Maternal Nicotine Exposure Alters Hippocampal Microglia Polarization and Promotes Anti-inflammatory Signaling in Juvenile Offspring in Mice.
Zhou L, Tao X, Pang G, Mu M, Sun Q, Liu F, Hu Y, Tao H, Li B, Xu K
Frontiers in pharmacology 2021;12:661304
Frontiers in pharmacology 2021;12:661304
MicroLet-7b Regulates Neutrophil Function and Dampens Neutrophilic Inflammation by Suppressing the Canonical TLR4/NF-κB Pathway.
Chen B, Han J, Chen S, Xie R, Yang J, Zhou T, Zhang Q, Xia R
Frontiers in immunology 2021;12:653344
Frontiers in immunology 2021;12:653344
SIRT1 Deacetylates TET2 and Promotes Its Ubiquitination Degradation to Achieve Neuroprotection Against Parkinson's Disease.
Li X, Liu T, Wu TT, Feng Y, Peng SJ, Yin H, Wu YC
Frontiers in neurology 2021;12:652882
Frontiers in neurology 2021;12:652882
The Arachidonic Acid Metabolism Mechanism Based on UPLC-MS/MS Metabolomics in Recurrent Spontaneous Abortion Rats.
Li M, Haixia Y, Kang M, An P, Wu X, Dang H, Xu X
Frontiers in endocrinology 2021;12:652807
Frontiers in endocrinology 2021;12:652807
Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer.
Peng HH, Wang JN, Xiao LF, Yan M, Chen SP, Wang L, Yang K
Frontiers in genetics 2021;12:651647
Frontiers in genetics 2021;12:651647
4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response.
Li R, Yang W, Yin Y, Ma X, Zhang P, Tao K
Frontiers in pharmacology 2021;12:651444
Frontiers in pharmacology 2021;12:651444
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
Dai H, Zhao N, Liu H, Zheng Y, Zhao L
Frontiers in pharmacology 2021;12:647124
Frontiers in pharmacology 2021;12:647124
STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis.
Liu ZZ, Yang YJ, Zhou CK, Yan SQ, Ma K, Gao Y, Chen W
Frontiers in immunology 2021;12:636861
Frontiers in immunology 2021;12:636861
Identification of miRNA in Sheep Intramuscular Fat and the Role of miR-193a-5p in Proliferation and Differentiation of 3T3-L1.
Han F, Zhou L, Zhao L, Wang L, Liu L, Li H, Qiu J, He J, Liu N
Frontiers in genetics 2021;12:633295
Frontiers in genetics 2021;12:633295
Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles.
Kumar P, Zadjali F, Yao Y, Siroky B, Astrinidis A, Gross KW, Bissler JJ
Frontiers in physiology 2021;12:630933
Frontiers in physiology 2021;12:630933
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock.
Dong R, Xue Z, Fan G, Zhang N, Wang C, Li G, Da Y
Frontiers in immunology 2021;12:620238
Frontiers in immunology 2021;12:620238
Proteomic Analysis of Red Ginseng on Prolonging the Life Span of Male Drosophila melanogaster.
Hou W, Pei J
Frontiers in pharmacology 2021;12:618123
Frontiers in pharmacology 2021;12:618123
Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in Rats.
Lv L, Chang Y, Li Y, Chen H, Yao J, Xie Y, Liang X, Yang X, Zhang M, Liu G
Frontiers in pharmacology 2021;12:616803
Frontiers in pharmacology 2021;12:616803
Fuyuan Xingnao Decoction Promotes Angiogenesis Through the Rab1/AT1R Pathway in Diabetes Mellitus Complicated With Cerebral Infarction.
Deng D, Qu Y, Sun L, Jia L, Bu J, Ye M, Chen Z, Geng Y, Zhou S, Fang B
Frontiers in pharmacology 2021;12:616165
Frontiers in pharmacology 2021;12:616165
Precise Investigation of the Efficacy of Multicomponent Drugs Against Pneumonia Infected With Influenza Virus.
Wei J, Sun J, Zeng J, Ji E, Xu J, Tang C, Huo H, Zhang Y, Li H, Yang H
Frontiers in pharmacology 2021;12:604009
Frontiers in pharmacology 2021;12:604009
Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development.
Lai MC, Zhu QQ, Xu J, Zhang WJ
American journal of cancer research 2021;11(9):4175-4198
American journal of cancer research 2021;11(9):4175-4198
3'untranslated regions (3'UTR) of Gelsolin mRNA displays anticancer effects in non-small cell lung cancer (NSCLC) cells.
Liu X, Huang X, Ma J, Li L, Hu H, Feng J, Gao X, Zhang Y, Liu L
American journal of cancer research 2021;11(8):3857-3876
American journal of cancer research 2021;11(8):3857-3876
Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma.
Cheng WC, Chang CY, Lo CC, Hsieh CY, Kuo TT, Tseng GC, Wong SC, Chiang SF, Huang KC, Lai LC, Lu TP, Chao KSC, Sher YP
Theranostics 2021;11(8):3661-3675
Theranostics 2021;11(8):3661-3675
Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer.
Zhu Y, Lam AKY, Shum DKY, Cui D, Zhang J, Yan DD, Li B, Xu WW, Lee NPY, Chan KT, Law S, Tsao SW, Cheung ALM
Theranostics 2021;11(6):2722-2741
Theranostics 2021;11(6):2722-2741
βKlotho, a direct target of miR-206, contributes to the growth of hepatoblastoma through augmenting PI3K/Akt/mTOR signaling.
Chen T, Chen J, Zhao X, Zhou J, Sheng Q, Zhu L, Lv Z
American journal of cancer research 2021;11(5):1982-2004
American journal of cancer research 2021;11(5):1982-2004
(125)I seed implantation brachytherapy for glottic carcinoma: an experimental and clinical study.
Jiao D, Zhou X, Yao Y, Chen J, Lei Q, Ren J, Han X
American journal of cancer research 2021;11(4):1321-1334
American journal of cancer research 2021;11(4):1321-1334
Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.
Lee MJ, Lee JC, Hsieh JH, Lin MY, Shih IA, You HL, Wang K
American journal of cancer research 2021;11(4):1247-1266
American journal of cancer research 2021;11(4):1247-1266
Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis.
Pan T, Zhou Q, Miao K, Zhang L, Wu G, Yu J, Xu Y, Xiong W, Li Y, Wang Y
Theranostics 2021;11(3):1192-1206
Theranostics 2021;11(3):1192-1206
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3.
Zhou L, Song Z, Hu J, Liu L, Hou Y, Zhang X, Yang X, Chen K
Theranostics 2021;11(2):841-860
Theranostics 2021;11(2):841-860
Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.
Liu J, Nie C, Xue L, Yan Y, Liu S, Sun J, Fan M, Qian H, Ying H, Wang L, Li Y
Theranostics 2021;11(17):8283-8300
Theranostics 2021;11(17):8283-8300
Fiber scaffold bioartificial liver therapy relieves acute liver failure and extrahepatic organ injury in pigs.
Weng J, Han X, Zeng F, Zhang Y, Feng L, Cai L, Liang K, Liu S, Li S, Fu G, Zeng M, Gao Y
Theranostics 2021;11(16):7620-7639
Theranostics 2021;11(16):7620-7639
Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.
Zhao H, Yang H, Geng C, Chen Y, Tang Y, Li Z, Pang J, Shu T, Nie Y, Liu Y, Jia K, Wang J
Theranostics 2021;11(15):7600-7615
Theranostics 2021;11(15):7600-7615
Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion.
Ding J, Zhang Y, Cai X, Zhang Y, Yan S, Wang J, Zhang S, Yin T, Yang C, Yang J
Theranostics 2021;11(12):5813-5830
Theranostics 2021;11(12):5813-5830
FAM21C Promotes Hepatocellular Carcinoma Invasion and Metastasis by Driving Actin Cytoskeleton Remodeling via Inhibiting Capping Ability of CAPZA1.
Lu Y, Huang D, Wang B, Zheng B, Liu J, Song J, Zheng S
Frontiers in oncology 2021;11:809195
Frontiers in oncology 2021;11:809195
CD248(+) Cancer-Associated Fibroblasts: A Novel Prognostic and Therapeutic Target for Renal Cell Carcinoma.
Xu C, Zhang K, Yang F, Zhou X, Liu S, Li Y, Ma S, Zhao X, Lu T, Lu S, Zhang J, Li H, Han D, Wen W, Qin W
Frontiers in oncology 2021;11:773063
Frontiers in oncology 2021;11:773063
Identification and Validation of TYMS as a Potential Biomarker for Risk of Metastasis Development in Hepatocellular Carcinoma.
Li S, Zhao J, Lv L, Dong D
Frontiers in oncology 2021;11:762821
Frontiers in oncology 2021;11:762821
Positive Reciprocal Feedback of lncRNA ZEB1-AS1 and HIF-1α Contributes to Hypoxia-Promoted Tumorigenesis and Metastasis of Pancreatic Cancer.
Jin Y, Zhang Z, Yu Q, Zeng Z, Song H, Huang X, Kong Q, Hu H, Xia Y
Frontiers in oncology 2021;11:761979
Frontiers in oncology 2021;11:761979
Novel Natural Inhibitors Targeting Enhancer of Zeste Homolog 2: A Comprehensive Structural Biology Research.
Li W, Ding Z, Zhao Y, Jiang M, Zhang S, Zhao H, Lei K, Xu R, Zhao Y, Wang D, Chao M, Yin Y, Yang C, Wang L, Yan M
Frontiers in oncology 2021;11:741403
Frontiers in oncology 2021;11:741403
Integrin Alpha-2 as a Potential Prognostic and Predictive Biomarker for Patients With Lower-Grade Glioma.
Lin L, Huang K, Tu Z, Zhu X, Li J, Lei K, Luo M, Wang P, Gong C, Long X, Wu L
Frontiers in oncology 2021;11:738651
Frontiers in oncology 2021;11:738651
CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
Li H, Weng Y, Wang S, Wang F, Wang Y, Kong P, Zhang L, Cheng C, Cui H, Xu E, Wei S, Guo D, Chen F, Bi Y, Meng Y, Cheng X, Cui Y
Frontiers in oncology 2021;11:734655
Frontiers in oncology 2021;11:734655
CK-3, A Novel Methsulfonyl Pyridine Derivative, Suppresses Hepatocellular Carcinoma Proliferation and Invasion by Blocking the PI3K/AKT/mTOR and MAPK/ERK Pathways.
Wu Q, Liu TY, Hu BC, Li X, Wu YT, Sun XT, Jiang XW, Wang S, Qin XC, Ding HW, Zhao QC
Frontiers in oncology 2021;11:717626
Frontiers in oncology 2021;11:717626
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Xie Q, Zhao S, Liu W, Cui Y, Li F, Li Z, Guo T, Yu W, Guo W, Deng W, Gu C
Frontiers in oncology 2021;11:702491
Frontiers in oncology 2021;11:702491
Hypoxia-Induced LncRNA-MIR210HG Promotes Cancer Progression By Inhibiting HIF-1α Degradation in Ovarian Cancer.
Liu P, Huang H, Qi X, Bian C, Cheng M, Liu L, Xue L, Zhao X, Yi T, Quan Y
Frontiers in oncology 2021;11:701488
Frontiers in oncology 2021;11:701488
TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma.
Bao S, Jiang X, Jin S, Tu P, Lu J
Frontiers in oncology 2021;11:694145
Frontiers in oncology 2021;11:694145
Downregulation of ATXN3 Enhances the Sensitivity to AKT Inhibitors (Perifosine or MK-2206), but Decreases the Sensitivity to Chemotherapeutic Drugs (Etoposide or Cisplatin) in Neuroblastoma Cells.
Gong B, Zhang J, Hua Z, Liu Z, Thiele CJ, Li Z
Frontiers in oncology 2021;11:686898
Frontiers in oncology 2021;11:686898
AUF1 Promotes Proliferation and Invasion of Thyroid Cancer via Downregulation of ZBTB2 and Subsequent TRIM58.
Du X, Wang JM, Zhang DL, Wu T, Zeng XY, Jiang JY, Du ZX
Frontiers in oncology 2021;11:681736
Frontiers in oncology 2021;11:681736
Prognostic and Predictive Value of Immune-Related Gene Pair Signature in Primary Lower-Grade Glioma Patients.
Lei K, Li J, Tu Z, Liu F, Ye M, Wu M, Zhu Y, Luo M, Lin L, Tao C, Huang K, Zhu X
Frontiers in oncology 2021;11:665870
Frontiers in oncology 2021;11:665870
DDX60 Is Associated With Glioma Malignancy and Serves as a Potential Immunotherapy Biomarker.
Zhang J, Fu M, Zhang M, Zhang J, Du Z, Zhang H, Hua W, Mao Y
Frontiers in oncology 2021;11:665360
Frontiers in oncology 2021;11:665360
Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma.
Li TH, Qin C, Zhao BB, Cao HT, Yang XY, Wang YY, Li ZR, Zhou XT, Wang WB
Frontiers in oncology 2021;11:665192
Frontiers in oncology 2021;11:665192
Targeting Mutated p53 Dependency in Triple-Negative Breast Cancer Cells Through CDK7 Inhibition.
Peng J, Yang M, Bi R, Wang Y, Wang C, Wei X, Zhang Z, Xie X, Wei W
Frontiers in oncology 2021;11:664848
Frontiers in oncology 2021;11:664848
The LncRNA CASC11 Promotes Colorectal Cancer Cell Proliferation and Migration by Adsorbing miR-646 and miR-381-3p to Upregulate Their Target RAB11FIP2.
Zhang W, Li X, Zhang W, Lu Y, Lin W, Yang L, Zhang Z, Li X
Frontiers in oncology 2021;11:657650
Frontiers in oncology 2021;11:657650
FOXP3 Inhibits the Metastasis of Breast Cancer by Downregulating the Expression of MTA1.
Liu C, Han J, Li X, Huang T, Gao Y, Wang B, Zhang K, Wang S, Zhang W, Li W, Hao Q, Li M, Zhang Y, Zhang C
Frontiers in oncology 2021;11:656190
Frontiers in oncology 2021;11:656190
Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer.
Gao C, Quan MY, Chen QJ, Yang R, Wu Y, Liu JY, Lin ZY, Li X, Cai JT, Jiang TF, Xu L, Mossahebi-Mohammadi M, Guo Q, Zhang JS
Frontiers in oncology 2021;11:649290
Frontiers in oncology 2021;11:649290
Molecular and Clinical Characterization of UBE2S in Glioma as a Biomarker for Poor Prognosis and Resistance to Chemo-Radiotherapy.
Hu L, Cheng X, Binder Z, Han Z, Yin Y, O'Rourke DM, Wang S, Feng Y, Weng C, Wu A, Lin Z
Frontiers in oncology 2021;11:640910
Frontiers in oncology 2021;11:640910
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Nisar MA, Zheng Q, Saleem MZ, Ahmmed B, Ramzan MN, Ud Din SR, Tahir N, Liu S, Yan Q
Frontiers in oncology 2021;11:618839
Frontiers in oncology 2021;11:618839
Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma.
Zhou W, Li J, Lu X, Liu F, An T, Xiao X, Kuo ZC, Wu W, He Y
Frontiers in oncology 2021;11:617289
Frontiers in oncology 2021;11:617289
MiR-338-5p Inhibits EGF-Induced EMT in Pancreatic Cancer Cells by Targeting EGFR/ERK Signaling.
Sun J, Chen L, Dong M
Frontiers in oncology 2021;11:616481
Frontiers in oncology 2021;11:616481
The Human Cytomegalovirus US31 Gene Predicts Favorable Survival and Regulates the Tumor Microenvironment in Gastric Cancer.
Ye S, Hu Y, Chen C, Chen S, Tong X, Zhu H, Deng B, Hu X, Sun X, Chen X, Shi X, Gu R, Xie W, Guo G, Xing D, Shen X, Xue X, Shen S
Frontiers in oncology 2021;11:614925
Frontiers in oncology 2021;11:614925
STAM Prolongs Clear Cell Renal Cell Carcinoma Patients' Survival via Inhibiting Cell Growth and Invasion.
Deng T, He Z, Duan X, Gu D, Cai C, Wu W, Liu Y, Zeng G
Frontiers in oncology 2021;11:611081
Frontiers in oncology 2021;11:611081
Canagliflozin Improves Liver Function in Rats by Upregulating Asparagine Synthetase.
Wang S, Ding Y, Dong R, Wang H, Yin L, Meng S
Pharmacology 2021;106(11-12):606-615
Pharmacology 2021;106(11-12):606-615
Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway.
Liu Q, Zheng B, Zhang Y, Huang W, Hong Q, Meng Y
Canadian journal of physiology and pharmacology 2021 Sep;99(9):885-893
Canadian journal of physiology and pharmacology 2021 Sep;99(9):885-893
Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage.
Liu J, He J, Huang Y, Ge L, Xiao H, Zeng L, Jiang Z, Lu M, Hu Z
Annals of translational medicine 2021 Sep;9(17):1362
Annals of translational medicine 2021 Sep;9(17):1362
Hyperoxia-induced S1P(1) signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia.
Sudhadevi T, Jafri A, Ha AW, Basa P, Thomas JM, Fu P, Wary K, Mehta D, Natarajan V, Harijith A
Cell biochemistry and biophysics 2021 Sep;79(3):561-573
Cell biochemistry and biophysics 2021 Sep;79(3):561-573
Melatonin and other indoles show antiviral activities against swine coronaviruses in vitro at pharmacological concentrations.
Zhai X, Wang N, Jiao H, Zhang J, Li C, Ren W, Reiter RJ, Su S
Journal of pineal research 2021 Sep;71(2):e12754
Journal of pineal research 2021 Sep;71(2):e12754
Secretions released from mesenchymal stem cells improve spermatogenesis restoration of cytotoxic treatment with busulfan in azoospermia mice.
Cai YT, Xiong CL, Liu TS, Shen SL, Rao JP, Qiu F
Andrologia 2021 Sep;53(8):e14144
Andrologia 2021 Sep;53(8):e14144
Diurnal hepatic CYP3A11 contributes to chronotoxicity of the pyrrolizidine alkaloid retrorsine in mice.
Guo L, Zhang L, Xu H, Yu P, Wang Z, Lu D, Chen M, Wu B
Xenobiotica; the fate of foreign compounds in biological systems 2021 Sep;51(9):1019-1028
Xenobiotica; the fate of foreign compounds in biological systems 2021 Sep;51(9):1019-1028
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Tsai WC, Yu TY, Chang GJ, Chang HN, Lin LP, Lin MS, Pang JS
The American journal of sports medicine 2021 Sep;49(11):3102-3112
The American journal of sports medicine 2021 Sep;49(11):3102-3112
Long noncoding RNA HOTAIR functions as ceRNA to regulate MMP2 in paraquat induced lung epithelial-mesenchymal transition.
Jia R, Li T, Wang N
Toxicology 2021 Sep;461:152891
Toxicology 2021 Sep;461:152891
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Zhang H, Qi J, Guo J, Wang Y, Guan Y, Fan J, Sui L, Xu Y, Kong L, Yan B, Kong Y
Cell biology international 2021 Sep;45(9):1957-1965
Cell biology international 2021 Sep;45(9):1957-1965
Retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGA1.
Liu Y, Wang Y, Xiao Y, Li X, Ruan S, Luo X, Wan X, Wang F, Sun X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21859
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21859
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
Wu J, Wu C, Xing F, Cao L, Zeng W, Guo L, Li P, Zhong Y, Jiang H, Luo M, Shi G, Bu L, Ji Y, Hou P, Peng H, Huang J, Li C, Guo D
Cell research 2021 Sep;31(9):998-1010
Cell research 2021 Sep;31(9):998-1010
Morinda citrifolia (Noni) Juice Suppresses A549 Human Lung Cancer Cells via Inhibiting AKT/Nuclear Factor-κ B Signaling Pathway.
Ma LD, Lin GB, Yang LB, Cao JL, Wang J, Chen QD, Li WQ, Zhong WJ
Chinese journal of integrative medicine 2021 Sep;27(9):688-695
Chinese journal of integrative medicine 2021 Sep;27(9):688-695
Yes-associated protein regulates the hepatoprotective effect of vitamin D receptor activation through promoting adaptive bile duct remodeling in cholestatic mice.
Xie J, Fan Y, Jia R, Yang F, Ma L, Li L
The Journal of pathology 2021 Sep;255(1):95-106
The Journal of pathology 2021 Sep;255(1):95-106
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Zhang Y, Su H, Wudu M, Ren H, Xu Y, Zhang Q, Jiang J, Wang Q, Jiang X, Zhang B, Liu Z, Zou Z, Qiu X
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity.
Li P, Jiang M, Li K, Li H, Zhou Y, Xiao X, Xu Y, Krishfield S, Lipsky PE, Tsokos GC, Zhang X
Nature immunology 2021 Sep;22(9):1107-1117
Nature immunology 2021 Sep;22(9):1107-1117
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment.
Ren X, Lv J, Fu Y, Zhang N, Zhang C, Dong Z, Chudhary M, Zhong S, Kong L, Kong H
Diabetes research and clinical practice 2021 Sep;179:109025
Diabetes research and clinical practice 2021 Sep;179:109025
Bone mesenchymal stem cells attenuate resiniferatoxin-induced neuralgia via inhibiting TRPA1-PKCδ-P38/MAPK-p-P65 pathway in mice.
Li NQ, Peng Z, Xu WW, An K, Wan L
Brain research bulletin 2021 Sep;174:92-102
Brain research bulletin 2021 Sep;174:92-102
Role of the SENP1-SIRT1 pathway in hyperoxia-induced alveolar epithelial cell injury.
Dong W, Zhu X, Liu X, Zhao X, Lei X, Kang L, Liu L
Free radical biology & medicine 2021 Sep;173:142-150
Free radical biology & medicine 2021 Sep;173:142-150
Genetic association scan of 32 osteoarthritis susceptibility genes identified TP63 associated with an endemic osteoarthritis, Kashin-Beck disease.
Cheng B, Liang C, Yang X, Li P, Liu L, Cheng S, Jia Y, Zhang L, Ma M, Qi X, Yao Y, Chu X, Ye J, Lu C, Guo X, Wen Y, Zhang F
Bone 2021 Sep;150:115997
Bone 2021 Sep;150:115997
Hsa_circ_0001021 regulates intestinal epithelial barrier function via sponging miR-224-5p in ulcerative colitis.
Li B, Li Y, Li L, Yu Y, Gu X, Liu C, Long X, Yu Y, Zuo X
Epigenomics 2021 Sep;13(17):1385-1401
Epigenomics 2021 Sep;13(17):1385-1401
Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration.
Yu H, Yang X, Xiao X, Xu M, Yang Y, Xue C, Li X, Wang S, Zhao RC
Aging and disease 2021 Sep;12(6):1423-1437
Aging and disease 2021 Sep;12(6):1423-1437
[ANXA8 Regulates Proliferation of Human Non-Small Lung Cancer Cells A549 via EGFR-AKT-mTOR Signaling Pathway].
Zhou GZ, Sun YH, Shi YY, Zhang Q, Zhang L, Cui LQ, Sun GC
Molekuliarnaia biologiia 2021 Sep-Oct;55(5):870-880
Molekuliarnaia biologiia 2021 Sep-Oct;55(5):870-880
Dipeptidyl peptidase-4 (DPP4) inhibitor sitagliptin alleviates liver inflammation of diabetic mice by acting as a ROS scavenger and inhibiting the NFκB pathway.
Wang X, Ke J, Zhu YJ, Cao B, Yin RL, Wang Y, Wei LL, Zhang LJ, Yang LY, Zhao D
Cell death discovery 2021 Sep 7;7(1):236
Cell death discovery 2021 Sep 7;7(1):236
Circβ-catenin promotes tumor growth and Warburg effect of gallbladder cancer by regulating STMN1 expression.
Wang S, Su T, Tong H, Zhou D, Ma F, Ding J, Hao Y, Shi W, Quan Z
Cell death discovery 2021 Sep 6;7(1):233
Cell death discovery 2021 Sep 6;7(1):233
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
Du Y, Zhang M, Liu X, Li Z, Hu M, Tian Y, Lv L, Zhang X, Liu Y, Zhang P, Zhou Y
EMBO reports 2021 Sep 6;22(9):e52576
EMBO reports 2021 Sep 6;22(9):e52576
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Zeng S, Chen L, Sun Q, Zhao H, Yang H, Ren S, Liu M, Meng X, Xu H
European journal of pharmacology 2021 Sep 5;906:174253
European journal of pharmacology 2021 Sep 5;906:174253
iTRAQ-based proteome analysis of porcine group A rotavirus-infected porcine IPEC-J2 intestinal epithelial cells.
Zhou J, Huang S, Fan B, Niu B, Guo R, Gu J, Gao S, Li B
Journal of proteomics 2021 Sep 30;248:104354
Journal of proteomics 2021 Sep 30;248:104354
The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe(-/-) Mice through Modulating Macrophage Functions.
Qian Z, Yang H, Li H, Liu C, Yang L, Qu Z, Li X
Biomedicines 2021 Sep 3;9(9)
Biomedicines 2021 Sep 3;9(9)
LncRNA MEG3 inhibits the proliferation of neural stem cells after ischemic stroke via the miR-493-5P/MIF axis.
Zhao F, Xing Y, Jiang P, Hu L, Deng S
Biochemical and biophysical research communications 2021 Sep 3;568:186-192
Biochemical and biophysical research communications 2021 Sep 3;568:186-192
Penetration Cascade of Size Switchable Nanosystem in Desmoplastic Stroma for Improved Pancreatic Cancer Therapy.
Zhao X, Yang X, Wang X, Zhao X, Zhang Y, Liu S, Anderson GJ, Kim SJ, Li Y, Nie G
ACS nano 2021 Sep 28;15(9):14149-14161
ACS nano 2021 Sep 28;15(9):14149-14161
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Zhang W, You B, Qi D, Qiu L, Ripley-Gonzalez JW, Zheng F, Fu S, Li C, Dun Y, Liu S
Scientific reports 2021 Sep 27;11(1):19116
Scientific reports 2021 Sep 27;11(1):19116
The dysfunction of parvalbumin interneurons mediated by microglia contributes to cognitive impairment induced by lipopolysaccharide challenge.
Mao M, Zhou Z, Sun M, Wang C, Sun J
Neuroscience letters 2021 Sep 25;762:136133
Neuroscience letters 2021 Sep 25;762:136133
Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer.
Sun Y, Ren D, Zhou Y, Shen J, Wu H, Jin X
Cell death & disease 2021 Sep 25;12(10):878
Cell death & disease 2021 Sep 25;12(10):878
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Ma S, Quan P, Yu C, Fan X, Yang S, Jia W, Zhang L, Wang F, Liu F, Yang L, Qin W, Yang X
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma.
Huang Y, Yang Q, Zheng Y, Lin L, Xu X, Xu XE, Silva TC, Hazawa M, Peng L, Cao H, Ding Y, Lu D, Berman BP, Xu LY, Li EM, Yin D
Nucleic acids research 2021 Sep 20;49(16):9246-9263
Nucleic acids research 2021 Sep 20;49(16):9246-9263
18β-Glycyrrhetinic acid inhibits IL-1β-induced inflammatory response in mouse chondrocytes and prevents osteoarthritic progression by activating Nrf2.
Chen B, Zhu D, Xie C, Shi Y, Ni L, Zhang H, Li S, Lu J, Xiao J, Xia W, Huang C, Wang X
Food & function 2021 Sep 20;12(18):8399-8410
Food & function 2021 Sep 20;12(18):8399-8410
Melatonin as Immune Potentiator for Enhancing Subunit Vaccine Efficacy against Bovine Viral Diarrhea Virus.
Wang YX, Yang GH, Zhang LL, Wang J, Wang JF
Vaccines 2021 Sep 18;9(9)
Vaccines 2021 Sep 18;9(9)
LHX9, a p53-binding protein, inhibits the progression of glioma by suppressing glycolysis.
Luo X, Ge J, Chen T, Liu J, Liu Z, Bi C, Lan S
Aging 2021 Sep 17;13(18):22109-22119
Aging 2021 Sep 17;13(18):22109-22119
Salvianolic acid-B improves fat graft survival by promoting proliferation and adipogenesis.
Sun JM, Ho CK, Gao Y, Chong CH, Zheng DN, Zhang YF, Yu L
Stem cell research & therapy 2021 Sep 17;12(1):507
Stem cell research & therapy 2021 Sep 17;12(1):507
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
Huang Y, Zhang H, Wang L, Liu C, Guo M, Tan H, Liu Z
Cancer cell international 2021 Sep 16;21(1):494
Cancer cell international 2021 Sep 16;21(1):494
Protective effects of dioscin against isoproterenol-induced cardiac hypertrophy via adjusting PKCε/ERK-mediated oxidative stress.
Li R, Qi Y, Yuan Q, Xu L, Gao M, Xu Y, Han X, Yin L, Liu C
European journal of pharmacology 2021 Sep 15;907:174277
European journal of pharmacology 2021 Sep 15;907:174277
TRAIL produced by SAM-1-activated CD4(+) and CD8(+) subgroup T cells induces apoptosis in human tumor cells through upregulation of death receptors.
Zhang G, Xu M, Zhang X, Ma L, Zhang H
Toxicology and applied pharmacology 2021 Sep 15;427:115656
Toxicology and applied pharmacology 2021 Sep 15;427:115656
LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling.
Guo S, Zhang Y, Wang S, Yang T, Ma B, Li X, Zhang Y, Jiang X
Toxicology letters 2021 Sep 15;348:50-58
Toxicology letters 2021 Sep 15;348:50-58
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
Zhang H, Li L, Hao M, Chen K, Lu Y, Qi J, Chen W, Ren L, Cai X, Chen C, Liu Z, Zhao B, Li Z, Hou P
Journal of ethnopharmacology 2021 Sep 15;277:114254
Journal of ethnopharmacology 2021 Sep 15;277:114254
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Zhu X, Yu Z, Feng L, Deng L, Fang Z, Liu Z, Li Y, Wu X, Qin L, Guo R, Zheng Y
Carbohydrate polymers 2021 Sep 15;268:118237
Carbohydrate polymers 2021 Sep 15;268:118237
Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness.
Lu X, Zhang H, Wang M, Qu F, Li J, Li R, Yan X
Ecotoxicology and environmental safety 2021 Sep 15;221:112440
Ecotoxicology and environmental safety 2021 Sep 15;221:112440
N-Myc promotes angiogenesis and therapeutic resistance of prostate cancer by TEM8.
Li M, Fang L, Kwantwi LB, He G, Luo W, Yang L, Huang Y, Yin S, Cai Y, Ma W, Zhan H, Tong Z, Zhang L, Liang C, Yin Y
Medical oncology (Northwood, London, England) 2021 Sep 14;38(10):127
Medical oncology (Northwood, London, England) 2021 Sep 14;38(10):127
Gypenoside Inhibits Bovine Viral Diarrhea Virus Replication by Interfering with Viral Attachment and Internalization and Activating Apoptosis of Infected Cells.
Yang G, Zhang J, Wang S, Wang J, Wang J, Zhu Y, Wang J
Viruses 2021 Sep 12;13(9)
Viruses 2021 Sep 12;13(9)
Hsa_circ_0001361 facilitates the progress of lung adenocarcinoma cells via targeting miR-525-5p/VMA21 axis.
Shen HY, Shi LX, Wang L, Fang LP, Xu W, Xu JQ, Fan BQ, Fan WF
Journal of translational medicine 2021 Sep 10;19(1):389
Journal of translational medicine 2021 Sep 10;19(1):389
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
Wu Z, Zhang Y, Liu Y, Chen X, Huang Z, Zhao X, He H, Deng Y
Life (Basel, Switzerland) 2021 Sep 10;11(9)
Life (Basel, Switzerland) 2021 Sep 10;11(9)
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
Yu P, Wang L, Tang F, Guo S, Liao H, Fan C, Yang Q
Life sciences 2021 Sep 1;280:119715
Life sciences 2021 Sep 1;280:119715
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
Hu S, Li Y, Wang B, Peng K
International immunopharmacology 2021 Oct;99:108048
International immunopharmacology 2021 Oct;99:108048
NRF2 deficiency sensitizes human keratinocytes to zinc oxide nanoparticles-induced autophagy and cytotoxicity.
Yin Y, Peng H, Shao J, Zhang J, Li Y, Pi J, Guo J
Environmental toxicology and pharmacology 2021 Oct;87:103721
Environmental toxicology and pharmacology 2021 Oct;87:103721
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming.
Tao L, Moreno-Smith M, Ibarra-García-Padilla R, Milazzo G, Drolet NA, Hernandez BE, Oh YS, Patel I, Kim JJ, Zorman B, Patel T, Kamal AHM, Zhao Y, Hicks J, Vasudevan SA, Putluri N, Coarfa C, Sumazin P, Perini G, Parchem RJ, Uribe RA, Barbieri E
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Oct;8(19):e2005047
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Oct;8(19):e2005047
CG223, a novel BET inhibitor, exerts TGF-β1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis.
Kaneshita S, Kida T, Yoshioka M, Nishioka K, Raje M, Sakashita A, Hirano A, Sagawa T, Kasahara A, Inoue T, Fujioka K, Nagahara H, Wada M, Kohno M, Strovel JW, Fletcher S, Ashihara E, Kawahito Y
Pulmonary pharmacology & therapeutics 2021 Oct;70:102057
Pulmonary pharmacology & therapeutics 2021 Oct;70:102057
A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury.
Sun H, Peng J, Cai S, Nie Q, Li T, Kellum JA, Eliaz I, Peng Z
Journal of critical care 2021 Oct;65:192-199
Journal of critical care 2021 Oct;65:192-199
W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34.
Nagaraja RY, Sherry DM, Fessler JL, Stiles MA, Li F, Multani K, Orock A, Ahmad M, Brush RS, Anderson RE, Agbaga MP, Deák F
Molecular neurobiology 2021 Oct;58(10):4921-4943
Molecular neurobiology 2021 Oct;58(10):4921-4943
Prednisolone induces osteocytes apoptosis by promoting Notum expression and inhibiting PI3K/AKT/GSK3β/β-catenin pathway.
Li C, Yang P, Liu B, Bu J, Liu H, Guo J, Hasegawa T, Si H, Li M
Journal of molecular histology 2021 Oct;52(5):1081-1095
Journal of molecular histology 2021 Oct;52(5):1081-1095
Downregulation of fibronectin 1 attenuates ATRA-induced inhibition of cell migration and invasion in neuroblastoma cells.
Tan X, Gong W, Chen B, Gong B, Hua Z, Zhang S, Chen Y, Li Q, Li Z
Molecular and cellular biochemistry 2021 Oct;476(10):3601-3612
Molecular and cellular biochemistry 2021 Oct;476(10):3601-3612
Pgc-1α Promotes Phosphorylation, Inflammation, and Apoptosis in H9c2 Cells During the Early Stage of Lipopolysaccharide Induction.
Huang Q, Liu DH, Chen CF, Han Y, Huang ZQ, Zhang JW, Zeng XM
Inflammation 2021 Oct;44(5):1771-1781
Inflammation 2021 Oct;44(5):1771-1781
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
Deng YJ, Lin XP, Li XQ, Lu PF, Cai Y, Liu LL, Pei GC, Han M
Current medical science 2021 Oct;41(5):880-887
Current medical science 2021 Oct;41(5):880-887
CCL2 is a critical mechano-responsive mediator in crosstalk between osteoblasts and bone mesenchymal stromal cells.
Yao Z, Chen P, Fan L, Chen P, Zhang X, Yu B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21851
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21851
The protective effect and potential mechanism of NRXN1 on learning and memory in ADHD rat models.
Zhang S, Wu D, Xu Q, You L, Zhu J, Wang J, Liu Z, Yang L, Tong M, Hong Q, Chi X
Experimental neurology 2021 Oct;344:113806
Experimental neurology 2021 Oct;344:113806
5-IP(7) is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Zhang X, Li N, Zhang J, Zhang Y, Yang X, Luo Y, Zhang B, Xu Z, Zhu Z, Yang X, Yan Y, Lin B, Wang S, Chen D, Ye C, Ding Y, Lou M, Wu Q, Hou Z, Zhang K, Liang Z, Wei A, Wang B, Wang C, Jiang N, Zhang W, Xiao G, Ma C, Ren Y, Qi X, Han W, Wang C, Rao F
Nature metabolism 2021 Oct;3(10):1400-1414
Nature metabolism 2021 Oct;3(10):1400-1414
POSTN Promotes the Proliferation of Spermatogonial Cells by Activating the Wnt/β-Catenin Signaling Pathway.
Li C, Cheng D, Xu P, Nie H, Zhang T, Pang X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2906-2915
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2906-2915
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
Wang TD, Xu SL, Yu ZY, Ni SB, Zhang C, Jiao ZX
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes.
Choy J, Kan Y, Cifelli S, Johnson J, Chen M, Shiao LL, Zhou H, Previs S, Lei Y, Johnstone R, Liaw A, Saigal A, Hu L, Ramos R, Visconti R, McElroy WT, Kreamer A, Wildey MJ, Peier A, Shin MK, Imbriglio J, Ren Z, Hoek M, Weinglass A, Ai X
SLAS discovery : advancing life sciences R & D 2021 Oct;26(9):1225-1237
SLAS discovery : advancing life sciences R & D 2021 Oct;26(9):1225-1237
Adiponectin regulates osteocytic MLO-Y4 cell apoptosis in a high-glucose environment through the AMPK/FoxO3a signaling pathway.
Zeng Y, Liang H, Guo Y, Feng Y, Yao Q
Journal of cellular physiology 2021 Oct;236(10):7088-7096
Journal of cellular physiology 2021 Oct;236(10):7088-7096
ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway.
Yu S, Wang S, Sun X, Wu Y, Zhao J, Liu J, Yang D, Jiang Y
Oncology letters 2021 Oct;22(4):736
Oncology letters 2021 Oct;22(4):736
Comprehensive analysis of differentially expressed genes reveals the promotive effects of UBE2T on colorectal cancer cell proliferation.
Luo M, Zhou Y
Oncology letters 2021 Oct;22(4):714
Oncology letters 2021 Oct;22(4):714
Gardnerella vaginalis induces NLRP3 inflammasome-mediated pyroptosis in macrophages and THP-1 monocytes.
Xiang N, Yin T, Chen T
Experimental and therapeutic medicine 2021 Oct;22(4):1174
Experimental and therapeutic medicine 2021 Oct;22(4):1174
Prophylactic treatment with BX795 blocks activation of AKT and its downstream targets to protect vaginal keratinocytes and vaginal epithelium from HSV-2 infection.
Madavaraju K, Yadavalli T, Singh SK, Qatanani F, Shukla D
Antiviral research 2021 Oct;194:105145
Antiviral research 2021 Oct;194:105145
Exogenous extracellular matrix proteins decrease cardiac fibroblast activation in stiffening microenvironment through CAPG.
Wang X, Pierre V, Liu C, Senapati S, Park PS, Senyo SE
Journal of molecular and cellular cardiology 2021 Oct;159:105-119
Journal of molecular and cellular cardiology 2021 Oct;159:105-119
Study on the potential nephrotoxicity and mutagenicity of aristolochic acid IVa and its mechanism.
Xian Z, Tian J, Zhang Y, Meng J, Zhao Y, Li C, Yi Y, Han J, Liu S, Wang L, Pan C, Wang D, Wang F, Liang A
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112081
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112081
The polypeptide OP3-4 induced osteogenic differentiation of bone marrow mesenchymal stem cells via protein kinase B/glycogen synthase kinase 3β/β-catenin pathway and promoted mandibular defect bone regeneration.
Li C, Yang P, Kou Y, Zhang D, Li M
Archives of oral biology 2021 Oct;130:105243
Archives of oral biology 2021 Oct;130:105243
Notum suppresses the osteogenic differentiation of periodontal ligament stem cells through the Wnt/Beta catenin signaling pathway.
Yang P, Li C, Kou Y, Jiang Y, Li D, Liu S, Lu Y, Hasegawa T, Li M
Archives of oral biology 2021 Oct;130:105211
Archives of oral biology 2021 Oct;130:105211
Arsenic sulfide reverses cisplatin resistance in non-small cell lung cancer in vitro and in vivo through targeting PD-L1.
Tian W, Sun Y, Cheng Y, Ma X, Du W, Shi W, Guo Q
Thoracic cancer 2021 Oct;12(19):2551-2563
Thoracic cancer 2021 Oct;12(19):2551-2563
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
Yang Y, Wu M, Cao D, Yang C, Jin J, Wu L, Hong X, Li W, Lu L, Li J, Wang X, Meng X, Zhang Z, Cheng J, Ye Y, Xiao H, Yu J, Deng L
Science advances 2021 Oct 8;7(41):eabf6290
Science advances 2021 Oct 8;7(41):eabf6290
PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation.
Li D, Taylor DH, van Wolfswinkel JC
Cell reports 2021 Oct 5;37(1):109776
Cell reports 2021 Oct 5;37(1):109776
Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD(+) to alleviate mitochondrial disease.
Liu S, Fu S, Wang G, Cao Y, Li L, Li X, Yang J, Li N, Shan Y, Cao Y, Ma Y, Dong M, Liu Q, Jiang H
Cell metabolism 2021 Oct 5;33(10):1974-1987.e9
Cell metabolism 2021 Oct 5;33(10):1974-1987.e9
Dietary curcumin supplementation promotes browning and energy expenditure in postnatal overfed rats.
Zhu X, Du S, Yan Q, Min C, Zhou N, Zhou W, Li X
Nutrition & metabolism 2021 Oct 30;18(1):97
Nutrition & metabolism 2021 Oct 30;18(1):97
Reciprocal regulation between ER stress and autophagy in renal tubular fibrosis and apoptosis.
Shu S, Wang H, Zhu J, Liu Z, Yang D, Wu W, Cai J, Chen A, Tang C, Dong Z
Cell death & disease 2021 Oct 29;12(11):1016
Cell death & disease 2021 Oct 29;12(11):1016
SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.
Ren D, Sun Y, Zhang D, Li D, Liu Z, Jin X, Wu H
Cancer letters 2021 Oct 28;519:277-288
Cancer letters 2021 Oct 28;519:277-288
TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway.
Lin DC, Zheng SY, Zhang ZG, Luo JH, Zhu ZL, Li L, Chen LS, Lin X, Sham JSK, Lin MJ, Zhou RX
Cancer letters 2021 Oct 28;519:211-225
Cancer letters 2021 Oct 28;519:211-225
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception.
Qin NX, Zhao YR, Shi WH, Zhou ZY, Zou KX, Yu CJ, Liu X, Dong ZH, Mao YT, Zhou CL, Yu JL, Liu XM, Sheng JZ, Ding GL, Zhao WL, Wu YT, Huang HF
Reproduction (Cambridge, England) 2021 Oct 28;162(6):437-448
Reproduction (Cambridge, England) 2021 Oct 28;162(6):437-448
Constructing a passive targeting and long retention therapeutic nanoplatform based on water-soluble, non-toxic and highly-stable core-shell poly(amino acid) nanocomplexes.
Wang X, Deng B, Yu M, Zeng T, Chen Y, Hu J, Wu Q, Li A
Biomaterials science 2021 Oct 26;9(21):7065-7075
Biomaterials science 2021 Oct 26;9(21):7065-7075
ZBTB38 suppresses prostate cancer cell proliferation and migration via directly promoting DKK1 expression.
Ding G, Lu W, Zhang Q, Li K, Zhou H, Wang F, Zhao C, Fan C, Wang J
Cell death & disease 2021 Oct 25;12(11):998
Cell death & disease 2021 Oct 25;12(11):998
DLX6-AS1 activated by H3K4me1 enhanced secondary cisplatin resistance of lung squamous cell carcinoma through modulating miR-181a-5p/miR-382-5p/CELF1 axis.
Zhao X, Wang J, Zhu R, Zhang J, Zhang Y
Scientific reports 2021 Oct 25;11(1):21014
Scientific reports 2021 Oct 25;11(1):21014
Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase.
Raghubir M, Azeem SM, Hasnat R, Rahman CN, Wong L, Yan S, Huang YQ, Zhagui R, Blyufer A, Tariq I, Tam C, Lhamo S, Cecilio L, Chowdhury Y, ChandThakuri S, Mahajan SS
Scientific reports 2021 Oct 25;11(1):20974
Scientific reports 2021 Oct 25;11(1):20974
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
Liang T, Shen L, Ji Y, Jia L, Dou Y, Guo L
Genes 2021 Oct 21;12(11)
Genes 2021 Oct 21;12(11)
Hepatic P38 Activation Modulates Systemic Metabolism Through Fgf21-Mediated Interorgan Communication.
Liu W, Sun C, Yan Y, Cao H, Niu Z, Shen S, Liu S, Wu Y, Li Y, Hui L, Li Y, Zhao L, Hu C, Ding Q, Jiang J, Ying H
Diabetes 2021 Oct 21;
Diabetes 2021 Oct 21;
Chromatin Accessibility and Transcriptomic Alterations in Murine Ovarian Granulosa Cells upon Deoxynivalenol Exposure.
Fan H, Ren Z, Xu C, Wang H, Wu Z, Rehman ZU, Wu S, Sun MA, Bao W
Cells 2021 Oct 20;10(11)
Cells 2021 Oct 20;10(11)
Deficiency of ER Ca(2+) sensor STIM1 in AgRP neurons confers protection against dietary obesity.
Chen Z, Pan S, Yin K, Zhang Y, Yuan X, Wang S, Yang S, Shen Q, Tang Y, Li J, Wang Y, Lu Y, Zhang G
Cell reports 2021 Oct 19;37(3):109868
Cell reports 2021 Oct 19;37(3):109868
Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling.
Tower RJ, Li Z, Cheng YH, Wang XW, Rajbhandari L, Zhang Q, Negri S, Uytingco CR, Venkatesan A, Zhou FQ, Cahan P, James AW, Clemens TL
Proceedings of the National Academy of Sciences of the United States of America 2021 Oct 19;118(42)
Proceedings of the National Academy of Sciences of the United States of America 2021 Oct 19;118(42)
The Role of Nrf2 Transcription Factor and Sp1-Nrf2 Protein Complex in Glutamine Transporter SN1 Regulation in Mouse Cortical Astrocytes Exposed to Ammonia.
Dąbrowska K, Skowrońska K, Popek M, Albrecht J, Zielińska M
International journal of molecular sciences 2021 Oct 18;22(20)
International journal of molecular sciences 2021 Oct 18;22(20)
Non-stoichiometric cobalt sulfide nanodots enhance photothermal and chemodynamic therapies against solid tumor.
Zhao L, Yang Q, Guo W, Zhang F, Yu K, Yang C, Qu F
Journal of colloid and interface science 2021 Oct 15;600:390-402
Journal of colloid and interface science 2021 Oct 15;600:390-402
Regulation of survivin protein stability by USP35 is evolutionarily conserved.
Wang W, Lin H, Zheng E, Hou Z, Liu Y, Huang W, Chen D, Feng J, Li J, Li L
Biochemical and biophysical research communications 2021 Oct 15;574:48-55
Biochemical and biophysical research communications 2021 Oct 15;574:48-55
Sulourea-coordinated Pd nanocubes for NIR-responsive photothermal/H(2)S therapy of cancer.
Guo X, Liu J, Jiang L, Gong W, Wu H, He Q
Journal of nanobiotechnology 2021 Oct 14;19(1):321
Journal of nanobiotechnology 2021 Oct 14;19(1):321
mTORC2 confers neuroprotection and potentiates immunity during virus infection.
Suryawanshi RK, Patil CD, Agelidis A, Koganti R, Ames JM, Koujah L, Yadavalli T, Madavaraju K, Shantz LM, Shukla D
Nature communications 2021 Oct 14;12(1):6020
Nature communications 2021 Oct 14;12(1):6020
An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.
Wang R, Liu J, Li K, Yang G, Chen S, Wu J, Xie X, Ren H, Pang Y
Journal of experimental & clinical cancer research : CR 2021 Oct 13;40(1):318
Journal of experimental & clinical cancer research : CR 2021 Oct 13;40(1):318
Selenium Restores Synaptic Deficits by Modulating NMDA Receptors and Selenoprotein K in an Alzheimer's Disease Model.
Zhang ZH, Chen C, Jia SZ, Cao XC, Liu M, Tian J, Hoffmann PR, Xu HX, Ni JZ, Song GL
Antioxidants & redox signaling 2021 Oct 10;35(11):863-884
Antioxidants & redox signaling 2021 Oct 10;35(11):863-884
Hydrogel loading functionalized PAMAM/shRNA complex for postsurgical glioblastoma treatment.
Song J, Zhang H, Wang D, Wang J, Zhou J, Zhang Z, Wang J, Hu Y, Xu Q, Xie C, Lu W, Liu M
Journal of controlled release : official journal of the Controlled Release Society 2021 Oct 10;338:583-592
Journal of controlled release : official journal of the Controlled Release Society 2021 Oct 10;338:583-592
Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways.
Okubo Y, Ohtake F, Igarashi K, Yasuhiko Y, Hirabayashi Y, Saga Y, Kanno J
Development (Cambridge, England) 2021 Oct 1;148(19)
Development (Cambridge, England) 2021 Oct 1;148(19)
Inclusion of a short hairpin RNA targeting BCL11A into a β-globin expressing vector allows concurrent synthesis of curative adult and fetal hemoglobin.
Pires Lourenco S, Jarocha D, Ghiaccio V, Guerra A, Abdulmalik O, La P, Zezulin A, Smith-Whitley K, Kwiatkowski JL, Guzikowski V, Nakamura Y, Raabe T, Breda L, Rivella S
Haematologica 2021 Oct 1;106(10):2740-2745
Haematologica 2021 Oct 1;106(10):2740-2745
Long non-coding RNA SNHG16 regulates E2F1 expression by sponging miR-20a-5p and aggravating proliferative diabetic retinopathy.
Li X, Guo C, Chen Y, Yu F
Canadian journal of physiology and pharmacology 2021 Nov;99(11):1207-1216
Canadian journal of physiology and pharmacology 2021 Nov;99(11):1207-1216
LncRNA 4344 promotes NLRP3-related neuroinflammation and cognitive impairment by targeting miR-138-5p.
Feng X, Zhan F, Luo D, Hu J, Wei G, Hua F, Xu G
Brain, behavior, and immunity 2021 Nov;98:283-298
Brain, behavior, and immunity 2021 Nov;98:283-298
The relationship between liver pathological inflammation degree and pyroptosis in chronic hepatitis B patients.
Wang Y, Li X, Chen Q, Jiao F, Shi C, Pei M, Wang L, Gong Z
Journal of medical virology 2021 Nov;93(11):6229-6235
Journal of medical virology 2021 Nov;93(11):6229-6235
Sulfuretin exerts diversified functions in the processing of amyloid precursor protein.
Chen J, Luo B, Zhong BR, Li KY, Wen QX, Song L, Xiang XJ, Zhou GF, Hu LT, Deng XJ, Ma YL, Chen GJ
Genes & diseases 2021 Nov;8(6):867-881
Genes & diseases 2021 Nov;8(6):867-881
The m(6) A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.
Yu J, She Y, Yang L, Zhuang M, Han P, Liu J, Lin X, Wang N, Chen M, Jiang C, Zhang Y, Yuan Y, Ji SJ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov;8(22):e2101329
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov;8(22):e2101329
Lactate anions participate in T cell cytokine production and function.
Wen J, Cheng S, Zhang Y, Wang R, Xu J, Ling Z, Ma L, Ai X, Sun B
Science China. Life sciences 2021 Nov;64(11):1895-1905
Science China. Life sciences 2021 Nov;64(11):1895-1905
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.
Chen Q, Liu S, Zhang K, Yu B, Zhang W, Zhang H, Chen X
Leukemia & lymphoma 2021 Nov;62(11):2648-2656
Leukemia & lymphoma 2021 Nov;62(11):2648-2656
P-element Induced WImpy protein-like RNA-mediated gene silencing 2 regulates tumor cell progression, apoptosis, and metastasis in oral squamous cell carcinoma.
Zhou S, Yang S, Li F, Hou J, Chang H
The Journal of international medical research 2021 Nov;49(11):3000605211053158
The Journal of international medical research 2021 Nov;49(11):3000605211053158
Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway.
Jia SZ, Xu XW, Zhang ZH, Chen C, Chen YB, Huang SL, Liu Q, Hoffmann PR, Song GL
Redox biology 2021 Nov;47:102154
Redox biology 2021 Nov;47:102154
Effect of Interleukin-1β on Gene Expression Signatures in Schwann Cells Associated with Neuropathic Pain.
Ma Y, Sun H, An S, Wang Z
Neurochemical research 2021 Nov;46(11):2958-2968
Neurochemical research 2021 Nov;46(11):2958-2968
AMOTL2 restrains transforming growth factor-β1-induced proliferation and extracellular matrix deposition of airway smooth muscle cells via the down-regulation of YAP1 activation.
Fang P, Deng WJ, Fan N, Shi J, Shi HY, Ou L, Pan JL, Yang SY
Environmental toxicology 2021 Nov;36(11):2225-2235
Environmental toxicology 2021 Nov;36(11):2225-2235
Autophagy coordinates chondrocyte development and early joint formation in zebrafish.
Moss JJ, Wirth M, Tooze SA, Lane JD, Hammond CL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e22002
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e22002
A luciferase-based approach for measuring HBGA blockade antibody titers against human norovirus.
van Loben Sels JM, Meredith LW, Sosnovtsev SV, de Graaf M, Koopmans MPG, Lindesmith LC, Baric RS, Green KY, Goodfellow IG
Journal of virological methods 2021 Nov;297:114196
Journal of virological methods 2021 Nov;297:114196
G protein-coupled estrogen receptor in the rostral ventromedial medulla contributes to the chronification of postoperative pain.
Xu JJ, Gao P, Wu Y, Yin SQ, Zhu L, Xu SH, Tang D, Cheung CW, Jiao YF, Yu WF, Li YH, Yang LQ
CNS neuroscience & therapeutics 2021 Nov;27(11):1313-1326
CNS neuroscience & therapeutics 2021 Nov;27(11):1313-1326
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E(2) Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
Chen Q, Li Z, Xu Z, Chen C, Wang J, Zhu J, Dong Z
Biological trace element research 2021 Nov;199(11):4119-4128
Biological trace element research 2021 Nov;199(11):4119-4128
Dynamic changes of activated AHR in microglia and astrocytes in the substantia nigra-striatum system in an MPTP-induced Parkinson's disease mouse model.
Zhou Y, Zhao WJ, Quan W, Qiao CM, Cui C, Hong H, Shi Y, Niu GY, Zhao LP, Shen YQ
Brain research bulletin 2021 Nov;176:174-183
Brain research bulletin 2021 Nov;176:174-183
Proteomic analysis of the influence of CO(2) pneumoperitoneum in cervical cancer cells.
Lv H, Zhou T, Rong F
Journal of cancer research and therapeutics 2021 Nov;17(5):1253-1260
Journal of cancer research and therapeutics 2021 Nov;17(5):1253-1260
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Hao W, Hao C, Wu C, Xu Y, Wu S, Lu X, Yang J, Jin C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
Modified citrus pectin prevents isoproterenol-induced cardiac hypertrophy associated with p38 signalling and TLR4/JAK/STAT3 pathway.
Li Y, Zhou WW, Sun JH, Yang HX, Xu GR, Zhang Y, Song QH, Zhang C, Liu WZ, Liu XC, Li AY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112178
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112178
Apatinib combined with Keytruda treatment induces apoptosis of gastric carcinoma cells through CES4/miR-616-5p/DUSP2 axis.
Zhang F, Yin Y, Xu W, Zhou Z, Sun X, Li P
Basic & clinical pharmacology & toxicology 2021 Nov;129(5):345-356
Basic & clinical pharmacology & toxicology 2021 Nov;129(5):345-356
Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway.
Zheng X, Li W, Xu H, Liu J, Ren L, Yang Y, Li S, Wang J, Ji T, Du G
Acta pharmaceutica Sinica. B 2021 Nov;11(11):3465-3480
Acta pharmaceutica Sinica. B 2021 Nov;11(11):3465-3480
CXCR4 promotes gefitinib resistance of Huh7 cells by activating the c-Met signaling pathway.
Zhao D, Yang Z, Chen C, Zhang Z, Yu Y, Li Z
FEBS open bio 2021 Nov;11(11):3115-3125
FEBS open bio 2021 Nov;11(11):3115-3125
Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway.
Wang XL, Chen F, Shi H, Zhang M, Yan L, Pei XY, Peng XD
International immunopharmacology 2021 Nov;100:108139
International immunopharmacology 2021 Nov;100:108139
An anaphase surveillance mechanism prevents micronuclei formation from frequent chromosome segregation errors.
Orr B, De Sousa F, Gomes AM, Afonso O, Ferreira LT, Figueiredo AC, Maiato H
Cell reports 2021 Nov 9;37(6):109783
Cell reports 2021 Nov 9;37(6):109783
LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis.
Zhou M, Wang S, Liu D, Zhou J
ACS biomaterials science & engineering 2021 Nov 8;7(11):5255-5268
ACS biomaterials science & engineering 2021 Nov 8;7(11):5255-5268
African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis.
Li T, Zhao G, Zhang T, Zhang Z, Chen X, Song J, Wang X, Li J, Huang L, Wen L, Li C, Zhao D, He X, Bu Z, Zheng J, Weng C
Viruses 2021 Nov 8;13(11)
Viruses 2021 Nov 8;13(11)
Dietary Nano-ZnO Is Absorbed via Endocytosis and ZIP Pathways, Upregulates Lipogenesis, and Induces Lipotoxicity in the Intestine of Yellow Catfish.
Chen SW, Lv WH, Wu K, Chen GH, Chen F, Song CC, Luo Z
International journal of molecular sciences 2021 Nov 7;22(21)
International journal of molecular sciences 2021 Nov 7;22(21)
Rotigotine-loaded microspheres exerts the antinociceptive effect via central dopaminergic system.
Li T, Wang L, Zhang L, Li B, Wang D, Zhang L, Wang T, Fu F
European journal of pharmacology 2021 Nov 5;910:174443
European journal of pharmacology 2021 Nov 5;910:174443
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.
Sun L, Wang W, Han C, Huang W, Sun Y, Fang K, Zeng Z, Yang Q, Pan Q, Chen T, Luo X, Chen Y
Molecular cell 2021 Nov 4;81(21):4493-4508.e9
Molecular cell 2021 Nov 4;81(21):4493-4508.e9
Degradation of WTAP blocks antiviral responses by reducing the m(6) A levels of IRF3 and IFNAR1 mRNA.
Ge Y, Ling T, Wang Y, Jia X, Xie X, Chen R, Chen S, Yuan S, Xu A
EMBO reports 2021 Nov 4;22(11):e52101
EMBO reports 2021 Nov 4;22(11):e52101
Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression.
Sales-Gil R, Kommer DC, de Castro IJ, Amin HA, Vinciotti V, Sisu C, Vagnarelli P
EMBO reports 2021 Nov 4;22(11):e52061
EMBO reports 2021 Nov 4;22(11):e52061
Local activation of α2 adrenergic receptors is required for vagus nerve stimulation induced motor cortical plasticity.
Tseng CT, Gaulding SJ, Dancel CLE, Thorn CA
Scientific reports 2021 Nov 4;11(1):21645
Scientific reports 2021 Nov 4;11(1):21645
Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors.
Xu X, Masubuchi T, Cai Q, Zhao Y, Hui E
eLife 2021 Nov 4;10
eLife 2021 Nov 4;10
KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.
Pang L, Tian H, Gao X, Wang W, Wang X, Zhang Z
Bioscience reports 2021 Nov 26;41(11)
Bioscience reports 2021 Nov 26;41(11)
Polyethylenimine-Poly(lactic-co-glycolic acid)(2) Nanoparticles Show an Innate Targeting Ability to the Submandibular Salivary Gland via the Muscarinic 3 Receptor.
Xu J, Wan K, Wang H, Shi X, Wang J, Zhong Y, Gao C, Zhang Y, Nie G
ACS central science 2021 Nov 24;7(11):1938-1948
ACS central science 2021 Nov 24;7(11):1938-1948
Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Smith PR, Loerch S, Kunder N, Stanowick AD, Lou TF, Campbell ZT
Nature communications 2021 Nov 23;12(1):6789
Nature communications 2021 Nov 23;12(1):6789
CircMYOF triggers progression and facilitates glycolysis via the VEGFA/PI3K/AKT axis by absorbing miR-4739 in pancreatic ductal adenocarcinoma.
Zheng D, Huang X, Peng J, Zhuang Y, Li Y, Qu J, Zhang S, Huang F
Cell death discovery 2021 Nov 22;7(1):362
Cell death discovery 2021 Nov 22;7(1):362
Genome-wide map of N(6)-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis.
Wu J, Yuan XH, Jiang W, Lu YC, Huang QL, Yang Y, Qie HJ, Liu JT, Sun HY, Tang LJ
World journal of gastroenterology 2021 Nov 21;27(43):7530-7545
World journal of gastroenterology 2021 Nov 21;27(43):7530-7545
A novel endoplasmic stress mediator, Kelch domain containing 7B (KLHDC7B), increased Harakiri (HRK) in the SubAB-induced apoptosis signaling pathway.
Yahiro K, Ogura K, Tsutsuki H, Iyoda S, Ohnishi M, Moss J
Cell death discovery 2021 Nov 19;7(1):360
Cell death discovery 2021 Nov 19;7(1):360
Blue Light Activated Rapamycin for Optical Control of Protein Dimerization in Cells and Zebrafish Embryos.
Courtney TM, Darrah KE, Horst TJ, Tsang M, Deiters A
ACS chemical biology 2021 Nov 19;16(11):2434-2443
ACS chemical biology 2021 Nov 19;16(11):2434-2443
Targeting Ferroptosis by Polydopamine Nanoparticles Protects Heart against Ischemia/Reperfusion Injury.
Zhang Y, Ren X, Wang Y, Chen D, Jiang L, Li X, Li T, Huo M, Li Q
ACS applied materials & interfaces 2021 Nov 17;13(45):53671-53682
ACS applied materials & interfaces 2021 Nov 17;13(45):53671-53682
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Xi H, Ren F, Li Y, Du Y, Wang L, Hu J
Biology of reproduction 2021 Nov 15;105(5):1344-1354
Biology of reproduction 2021 Nov 15;105(5):1344-1354
Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation.
Lin XT, Yu HQ, Fang L, Tan Y, Liu ZY, Wu D, Zhang J, Xiong HJ, Xie CM
eLife 2021 Nov 15;10
eLife 2021 Nov 15;10
Ochratoxin A Induces Steatosis via PPARγ-CD36 Axis.
Zheng QW, Ding XF, Cao HJ, Ni QZ, Zhu B, Ma N, Zhang FK, Wang YK, Xu S, Chen TW, Xia J, Qiu XS, Yu DZ, Xie D, Li JJ
Toxins 2021 Nov 13;13(11)
Toxins 2021 Nov 13;13(11)
BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2.
Sutar Y, Yadavalli T, Paul SK, Mallick S, Koganti R, Chauhan H, Date AA, Shukla D
Pharmaceutics 2021 Nov 12;13(11)
Pharmaceutics 2021 Nov 12;13(11)
Overexpression of miR-224-5p alleviates allergic rhinitis in mice via the TLR4/MyD88/NF-κB pathway.
Wu J, Wu L, Zhang L, Xu H, Wang M, Wang L, Chen J, Sun K
Experimental animals 2021 Nov 10;70(4):440-449
Experimental animals 2021 Nov 10;70(4):440-449
Moderate-intensity exercise alleviates pyroptosis by promoting autophagy in osteoarthritis via the P2X7/AMPK/mTOR axis.
Li Z, Huang Z, Zhang H, Lu J, Tian Y, Piao S, Lin Z, Bai L
Cell death discovery 2021 Nov 10;7(1):346
Cell death discovery 2021 Nov 10;7(1):346
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Xu X, Sun X, Wan X, Chen X, Jiang X
Toxicology letters 2021 Nov 1;352:61-69
Toxicology letters 2021 Nov 1;352:61-69
Malignant transformation of human bronchial epithelial cells induced by benzo [a] pyrene suggests a negative feedback of TP53 to PPP1R13L via binding a possible enhancer element.
Zhang G, Yu T, Zhang Q, Zhang H, Xiao M, Cui S, Zhao Y, Lu X
Chemico-biological interactions 2021 Nov 1;349:109683
Chemico-biological interactions 2021 Nov 1;349:109683
Lipoxin A4 inhibits ovalbumin-induced airway inflammation and airway remodeling in a mouse model of asthma.
Liu Y, Wei L, He C, Chen R, Meng L
Chemico-biological interactions 2021 Nov 1;349:109660
Chemico-biological interactions 2021 Nov 1;349:109660
Selenite induced breast cancer MCF7 cells apoptosis through endoplasmic reticulum stress and oxidative stress pathway.
Cao L, Zhang J, Du Y, Sun M, Xiang Y, Sheng Y, Ren X, Shao J
Chemico-biological interactions 2021 Nov 1;349:109651
Chemico-biological interactions 2021 Nov 1;349:109651
Anti-glioblastoma effects of nanomicelle-curcumin plus erlotinib.
Bagherian A, Roudi B, Masoudian N, Mirzaei H
Food & function 2021 Nov 1;12(21):10926-10937
Food & function 2021 Nov 1;12(21):10926-10937
IDO1 as a new immune biomarker for diabetic nephropathy and its correlation with immune cell infiltration.
Yu K, Li D, Xu F, Guo H, Feng F, Ding Y, Wan X, Sun N, Zhang Y, Fan J, Liu L, Yang H, Yang X
International immunopharmacology 2021 May;94:107446
International immunopharmacology 2021 May;94:107446
Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways.
Tao Y, Sun Y, Wu B, Xu D, Yang J, Gu L, Du C
International immunopharmacology 2021 May;94:107427
International immunopharmacology 2021 May;94:107427
Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.
Wu K, Chen GH, Hogstrand C, Ling SC, Wu LX, Luo Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
Myeloid TBK1 Deficiency Induces Motor Deficits and Axon Degeneration Through Inflammatory Cell Infiltration.
Duan W, Yi L, Tian Y, Huang HP, Li Z, Bi Y, Guo M, Li Y, Liu Y, Ma Y, Song X, Liu Y, Li C
Molecular neurobiology 2021 May;58(5):2435-2446
Molecular neurobiology 2021 May;58(5):2435-2446
Postnatal deletion of Bmal1 in mice protects against obstructive renal fibrosis via suppressing Gli2 transcription.
Zhang J, Liu C, Liang Q, Zheng F, Guan Y, Yang G, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21530
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21530
The Role of Autophagy in Murine Cytomegalovirus Hepatitis.
Zhang LL, Zhang XY, Lu YY, Bi YD, Liu XL, Fang F
Viral immunology 2021 May;34(4):241-255
Viral immunology 2021 May;34(4):241-255
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Guo C, Li N, Dong C, Wang L, Li Z, Liu Q, Ma Q, Greenaway FT, Tian Y, Hao L, Liu S, Sun MZ
Journal of advanced research 2021 May;30:85-102
Journal of advanced research 2021 May;30:85-102
Effect of Kangquan Recipe () on BAMBI Expression in Hypothalamic-Pituitary-Prostate in Rats with Benign Prostatic Hyperplasia.
Chen WF, Yang ZB, Peng AX, Huang XQ, Su H, Chen TT, Huang YP
Chinese journal of integrative medicine 2021 May;27(5):361-368
Chinese journal of integrative medicine 2021 May;27(5):361-368
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Gu X, Li X, Jin Y, Zhang Z, Li M, Liu D, Wei F
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Qin X, Lin X, Liu L, Li Y, Li X, Deng Z, Chen H, Chen H, Niu Z, Li Z, Hu Y
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Berberine ameliorates the LPS-induced imbalance of osteogenic and adipogenic differentiation in rat bone marrow-derived mesenchymal stem cells.
Zhou R, Chen F, Liu H, Zhu X, Wen X, Yu F, Shang G, Qi S, Xu Y
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF‑κB signaling.
Ma B, Wang X, Zhang R, Niu S, Rong Z, Ni L, Di X, Han Q, Liu C
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Galectin‑3 facilitates the proliferation and migration of nasopharyngeal carcinoma cells via activation of the ERK1/2 and Akt signaling pathways, and is positively correlated with the inflammatory state of nasopharyngeal carcinoma.
Li M, Chen YB, Liu F, Qu JQ, Ren LC, Chai J, Tang CE
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway.
Wang Y, Chang T, Wu T, Ye W, Wang Y, Dou G, Du H, Hui Y, Guo C
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Wang HL, Xing GD, Qian Y, Sun XF, Zhong JF, Chen KL
Ecotoxicology and environmental safety 2021 May;214:112078
Ecotoxicology and environmental safety 2021 May;214:112078
IRF2BP2 prevents ox-LDL-induced inflammation and EMT in endothelial cells via regulation of KLF2.
Jiang Y, Shen Q
Experimental and therapeutic medicine 2021 May;21(5):481
Experimental and therapeutic medicine 2021 May;21(5):481
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Wang C, Wang X, Han A, Wang Y, Jiang H
Experimental and therapeutic medicine 2021 May;21(5):470
Experimental and therapeutic medicine 2021 May;21(5):470
MicroRNA-365b-3p represses the proliferation and promotes the apoptosis of non-small cell lung cancer cells by targeting PPP5C.
Zhang X, Wang J, Pan Y, Zhao J, Pan Y, Yan Y, Shen Z
Oncology letters 2021 May;21(5):389
Oncology letters 2021 May;21(5):389
Knockdown of CLN5 inhibits the tumorigenic properties of glioblastoma cells via the Akt/mTOR signaling pathway.
Xing J, Li Y, Zhao H
Oncology letters 2021 May;21(5):387
Oncology letters 2021 May;21(5):387
Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.
Xu S, Jiang N, Nawaz W, Liu B, Zhang F, Liu Y, Wu X, Wu Z
PLoS pathogens 2021 May;17(5):e1009587
PLoS pathogens 2021 May;17(5):e1009587
A Ran-binding protein facilitates nuclear import of human papillomavirus type 16.
Lai KY, Rizzato M, Aydin I, Villalonga-Planells R, Drexler HCA, Schelhaas M
PLoS pathogens 2021 May;17(5):e1009580
PLoS pathogens 2021 May;17(5):e1009580
Pannexin 1, a large-pore membrane channel, contributes to hypotonicity-induced ATP release in Schwann cells.
Wei ZY, Qu HL, Dai YJ, Wang Q, Ling ZM, Su WF, Zhao YY, Shen WX, Chen G
Neural regeneration research 2021 May;16(5):899-904
Neural regeneration research 2021 May;16(5):899-904
miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF.
Tong L, Li MD, Nie PY, Chen Y, Chen YL, Ji LL
Neurobiology of stress 2021 May;14:100311
Neurobiology of stress 2021 May;14:100311
Effects of saikosaponin-d on CYP3A4 in HepaRG cell and protein-ligand docking study.
Li H, Tang Y, Wei W, Yin C, Tang F
Basic & clinical pharmacology & toxicology 2021 May;128(5):661-668
Basic & clinical pharmacology & toxicology 2021 May;128(5):661-668
Downregulation of long non-coding RNA LOC101928477 correlates with tumor progression by regulating the epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Kong D, Long D, Liu B, Pei D, Cao N, Zhang G, Xia Z, Luo M
Thoracic cancer 2021 May;12(9):1303-1311
Thoracic cancer 2021 May;12(9):1303-1311
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Sun F, Wang Z, Wang X
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7.
Yan J, Yang Y, Fan X, Tang Y, Tang Z
Genes 2021 May 8;12(5)
Genes 2021 May 8;12(5)
Long non-coding RNA TP73-AS1 promotes pancreatic cancer growth and metastasis through miRNA-128-3p/GOLM1 axis.
Wang B, Sun X, Huang KJ, Zhou LS, Qiu ZJ
World journal of gastroenterology 2021 May 7;27(17):1993-2014
World journal of gastroenterology 2021 May 7;27(17):1993-2014
Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis.
Wang YP, Sharda A, Xu SN, van Gastel N, Man CH, Choi U, Leong WZ, Li X, Scadden DT
Cell metabolism 2021 May 4;33(5):1027-1041.e8
Cell metabolism 2021 May 4;33(5):1027-1041.e8
Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis.
Liu T, Liu B, Liu Y, Feng X, Jiang X, Long J, Gao Q, Yang Z
Cancer cell international 2021 May 31;21(1):287
Cancer cell international 2021 May 31;21(1):287
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Zhang C, Li Q, Qin G, Zhang Y, Li C, Han L, Wang R, Wang S, Chen H, Liu K, He C
Chinese medicine 2021 May 31;16(1):41
Chinese medicine 2021 May 31;16(1):41
FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
Criado-Marrero M, Gebru NT, Gould LA, Blazier DM, Vidal-Aguiar Y, Smith TM, Abdelmaboud SS, Shelton LB, Wang X, Dahrendorff J, Beaulieu-Abdelahad D, Dickey CA, Blair LJ
NPJ aging and mechanisms of disease 2021 May 3;7(1):9
NPJ aging and mechanisms of disease 2021 May 3;7(1):9
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Ren M, Xu H, Xia H, Tang Q, Bi F
Cell death discovery 2021 May 29;7(1):125
Cell death discovery 2021 May 29;7(1):125
Integrated analysis of long non-coding RNAs (lncRNAs) and mRNA expression profiles identifies lncRNA PRKG1-AS1 playing important roles in skeletal muscle aging.
Zheng Y, Liu T, Li Q, Li J
Aging 2021 May 29;13(11):15044-15060
Aging 2021 May 29;13(11):15044-15060
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients.
Ren S, Xiong H, Chen J, Yang X, Liu Y, Guo J, Jiang T, Xu Z, Yuan M, Liu Y, Zhou N, Chen H, Li W, Machens HG, Chen Z
Stem cell research & therapy 2021 May 29;12(1):313
Stem cell research & therapy 2021 May 29;12(1):313
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Ma Y, Wang L, He F, Yang J, Ding Y, Ge S, Fan X, Zhou Y, Xu X, Jia R
Cancer letters 2021 May 28;506:67-82
Cancer letters 2021 May 28;506:67-82
LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.
Huang Y, Lin Y, Song X, Wu D
Carcinogenesis 2021 May 28;42(5):733-741
Carcinogenesis 2021 May 28;42(5):733-741
Validation of the functions and prognostic values of synapse-associated proteins in lower-grade glioma.
Lin H, Yang Y, Hou C, Huang Y, Zhou L, Zheng J, Lv G, Mao R, Chen S, Xu P, Zhou Y, Wang P, Zhou D
Bioscience reports 2021 May 28;41(5)
Bioscience reports 2021 May 28;41(5)
Nuclear exosome HMGB3 secreted by nasopharyngeal carcinoma cells promotes tumour metastasis by inducing angiogenesis.
Zhang K, Liu D, Zhao J, Shi S, He X, Da P, You Y, You B
Cell death & disease 2021 May 28;12(6):554
Cell death & disease 2021 May 28;12(6):554
Effects of increasing intake of soybean oil on synthesis of testosterone in Leydig cells.
Su Y, Tian Z, Qi X, Luo D, Liu L, Liu S, Zheng D, Wei F, He Z, Guan Q
Nutrition & metabolism 2021 May 26;18(1):53
Nutrition & metabolism 2021 May 26;18(1):53
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
Yin W, Zhu H, Tan J, Xin Z, Zhou Q, Cao Y, Wu Z, Wang L, Zhao M, Jiang X, Ren C, Tang G
Cancer cell international 2021 May 25;21(1):276
Cancer cell international 2021 May 25;21(1):276
MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation.
Zhang B, Xiao J, Cheng X, Liu T
Biochemical and biophysical research communications 2021 May 21;554:63-70
Biochemical and biophysical research communications 2021 May 21;554:63-70
[Development and functional validation of a nano-delivery system of miR-16/polypeptide targeting ovarian cancer cells].
Li Q, Cen B, Huang W, Chen J, Chen Z, Pang J, Fu W, He S, Ji A
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 May 20;41(5):736-746
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 May 20;41(5):736-746
GSDMD contributes to host defence against Staphylococcus aureus skin infection by suppressing the Cxcl1-Cxcr2 axis.
Liu ZZ, Yang YJ, Zhou FH, Ma K, Lin XQ, Yan SQ, Gao Y, Chen W
Veterinary research 2021 May 19;52(1):71
Veterinary research 2021 May 19;52(1):71
The small-molecule protein ligand interface stabiliser E7820 induces differential cell line specific responses of integrin α2 expression.
Hülskamp MD, Kronenberg D, Stange R
BMC cancer 2021 May 18;21(1):571
BMC cancer 2021 May 18;21(1):571
Histone chaperone CAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies.
Ma X, Chen T, Peng Z, Wang Z, Liu J, Yang T, Wu L, Liu G, Zhou M, Tong M, Guan Y, Zhang X, Lin Y, Tang X, Li L, Tang Z, Pan T, Zhang H
The EMBO journal 2021 May 17;40(10):e106632
The EMBO journal 2021 May 17;40(10):e106632
Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.
Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J, Li D
Molecules (Basel, Switzerland) 2021 May 17;26(10)
Molecules (Basel, Switzerland) 2021 May 17;26(10)
CD157 in bone marrow mesenchymal stem cells mediates mitochondrial production and transfer to improve neuronal apoptosis and functional recovery after spinal cord injury.
Li J, Li H, Cai S, Bai S, Cai H, Zhang X
Stem cell research & therapy 2021 May 17;12(1):289
Stem cell research & therapy 2021 May 17;12(1):289
Long noncoding RNA LYPLAL1-AS1 regulates adipogenic differentiation of human mesenchymal stem cells by targeting desmoplakin and inhibiting the Wnt/β-catenin pathway.
Yang Y, Fan J, Xu H, Fan L, Deng L, Li J, Li D, Li H, Zhang F, Zhao RC
Cell death discovery 2021 May 15;7(1):105
Cell death discovery 2021 May 15;7(1):105
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Lai X, Wang M, Zhu Y, Feng X, Liang H, Wu J, Nie L, Li L, Shao L
Journal of hazardous materials 2021 May 15;410:124566
Journal of hazardous materials 2021 May 15;410:124566
HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
Song D, Guo M, Xu S, Song X, Bai B, Li Z, Chen J, An Y, Nie Y, Wu K, Wang S, Zhao Q
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):170
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):170
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Long Y, Wang Z, Fan J, Yuan L, Tong C, Zhao Y, Liu B
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
Zhang J, Huang F, Xia B, Yuan Y, Yu F, Wang G, Chen Q, Wang Q, Li Y, Li R, Song Z, Pan T, Chen J, Lu G, Zhang H
Signal transduction and targeted therapy 2021 May 12;6(1):189
Signal transduction and targeted therapy 2021 May 12;6(1):189
CircRNA_30032 promotes renal fibrosis in UUO model mice via miRNA-96-5p/HBEGF/KRAS axis.
Yi L, Ai K, Li H, Qiu S, Li Y, Wang Y, Li X, Zheng P, Chen J, Wu D, Xiang X, Chai X, Yuan Y, Zhang D
Aging 2021 May 11;13(9):12780-12799
Aging 2021 May 11;13(9):12780-12799
IFIT5 Negatively Regulates the Type I IFN Pathway by Disrupting TBK1-IKKε-IRF3 Signalosome and Degrading IRF3 and IKKε.
Zhang N, Shi H, Yan M, Liu G
Journal of immunology (Baltimore, Md. : 1950) 2021 May 1;206(9):2184-2197
Journal of immunology (Baltimore, Md. : 1950) 2021 May 1;206(9):2184-2197
Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway.
Xiao Y, Deng J, Li C, Gong X, Gui Z, Huang J, Zhang Y, Liu Y, Ye X, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153488
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153488
Tak1 in the astrocytes of mediobasal hypothalamus regulates anxiety-like behavior in mice.
Zhao F, Zhang T, Shen Q, Yin K, Wang Y, Zhang G
Glia 2021 Mar;69(3):609-618
Glia 2021 Mar;69(3):609-618
Curcumin combined with low-intensity ultrasound suppresses the growth of glioma cells via inhibition of the AKT pathway.
Shi G, Zhang Z, Fang Y, Bian D, Bai Z
Neoplasma 2021 Mar;68(2):290-297
Neoplasma 2021 Mar;68(2):290-297
Stromal cell-derived factor-1/Exendin-4 cotherapy facilitates the proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells in vitro and promotes periodontal bone regeneration in vivo.
Liang Q, Du L, Zhang R, Kang W, Ge S
Cell proliferation 2021 Mar;54(3):e12997
Cell proliferation 2021 Mar;54(3):e12997
SREBP1 suppresses the differentiation and epithelial function of hiPSC-derived endothelial cells by inhibiting the microRNA199b-5p pathway.
Qian X, Guo X, Ni Q, Wang H, Ye M, Zhang L
Stem cell research 2021 Mar;51:102174
Stem cell research 2021 Mar;51:102174
miR-132 Regulates PTSD-like Behaviors in Rats Following Single-Prolonged Stress Through Fragile X-Related Protein 1.
Nie PY, Ji LL, Fu CH, Peng JB, Wang ZY, Tong L
Cellular and molecular neurobiology 2021 Mar;41(2):327-340
Cellular and molecular neurobiology 2021 Mar;41(2):327-340
Cordyceps acid alleviates lung cancer in nude mice.
Wang J, Chen H, Li W, Shan L
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling.
Li D, Cui Y, Wang X, Liu F, Li X
Phytotherapy research : PTR 2021 Mar;35(3):1416-1431
Phytotherapy research : PTR 2021 Mar;35(3):1416-1431
Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis.
Shao Z, Wang B, Shi Y, Xie C, Huang C, Chen B, Zhang H, Zeng G, Liang H, Wu Y, Zhou Y, Tian N, Wu A, Gao W, Wang X, Zhang X
Osteoarthritis and cartilage 2021 Mar;29(3):413-422
Osteoarthritis and cartilage 2021 Mar;29(3):413-422
Caveolae/rafts protect human cerebral microvascular endothelial cells from Streptococcus suis serotype 2 α-enolase-mediated injury.
Jiang H, Wu T, Liu J, Yu X, Liu H, Bao C, Liu M, Ji Y, Feng X, Gu J, Han W, Li N, Lei L
Veterinary microbiology 2021 Mar;254:108981
Veterinary microbiology 2021 Mar;254:108981
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction.
Zhu X, Wang F, Lei X, Dong W
Experimental biology and medicine (Maywood, N.J.) 2021 Mar;246(5):596-606
Experimental biology and medicine (Maywood, N.J.) 2021 Mar;246(5):596-606
RPL41 sensitizes retinoblastoma cells to chemotherapeutic drugs via ATF4 degradation.
Geng W, Ren J, Shi H, Qin F, Xu X, Xiao S, Jiao Y, Wang A
Journal of cellular physiology 2021 Mar;236(3):2214-2225
Journal of cellular physiology 2021 Mar;236(3):2214-2225
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
Wu J, Li Y, Liu J, Xu Y
The journal of gene medicine 2021 Mar;23(3):e3293
The journal of gene medicine 2021 Mar;23(3):e3293
MiR-205 Inhibits Sporadic Vestibular Schwannoma Cell Proliferation by Targeting Cyclin-Dependent Kinase 14.
Yin X, Huo Z, Yan S, Wang Z, Yang T, Wu H, Zhang Z
World neurosurgery 2021 Mar;147:e25-e31
World neurosurgery 2021 Mar;147:e25-e31
Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver.
Tamai Y, Chen Z, Wu Y, Okabe J, Kobayashi Y, Chiba H, Hui SP, Eguchi A, Iwasa M, Ito M, Takei Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111181
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111181
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Gao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Journal of extracellular vesicles 2021 Mar;10(5):e12060
CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing.
Tosat-Bitrián C, Avis-Bodas A, Porras G, Borrego-Hernández D, García-Redondo A, Martín-Requero A, Palomo V
Nanomaterials (Basel, Switzerland) 2021 Mar 9;11(3)
Nanomaterials (Basel, Switzerland) 2021 Mar 9;11(3)
Effects of PI3K/AKT/mTOR pathway regulation of HIF-1α on Lanthanum-induced neurotoxicity in rats.
Ding Z, Zhang J, Hu Y, Li N, Yu S, Zheng L, Lin L
Brain research 2021 Mar 9;:147400
Brain research 2021 Mar 9;:147400
Exosomal miR-365a-5p derived from HUC-MSCs regulates osteogenesis in GIONFH through the Hippo signaling pathway.
Kuang MJ, Zhang KH, Qiu J, Wang AB, Che WW, Li XM, Shi DL, Wang DC
Molecular therapy. Nucleic acids 2021 Mar 5;23:565-576
Molecular therapy. Nucleic acids 2021 Mar 5;23:565-576
The RNA-Binding Protein CELF2 Inhibits Ovarian Cancer Progression by Stabilizing FAM198B.
Guo Q, Wu Y, Guo X, Cao L, Xu F, Zhao H, Zhu J, Wen H, Ju X, Wu X
Molecular therapy. Nucleic acids 2021 Mar 5;23:169-184
Molecular therapy. Nucleic acids 2021 Mar 5;23:169-184
Cerebral Cavernous Malformation 1 Determines YAP/TAZ Signaling-Dependent Metastatic Hallmarks of Prostate Cancer Cells.
Park S, Lee HY, Kim J, Park H, Ju YS, Kim EG, Kim J
Cancers 2021 Mar 5;13(5)
Cancers 2021 Mar 5;13(5)
Sildenafil improves right ventricular remodelling in monocrotaline-induced rats by decreasing myocardial apoptosis and activating peroxisome proliferator-activated receptors.
Li YL, Li YQ, Zeng FQ, Lin XY, Li XT, Ren XQ, Yang DL
The Journal of pharmacy and pharmacology 2021 Mar 4;73(2):145-151
The Journal of pharmacy and pharmacology 2021 Mar 4;73(2):145-151
PTEN deficiency facilitates the therapeutic vulnerability to proteasome inhibitor bortezomib in gallbladder cancer.
Jiang TY, Feng XF, Fang Z, Cui XW, Lin YK, Pan YF, Yang C, Ding ZW, Zhang YJ, Tan YX, Wang HY, Dong LW
Cancer letters 2021 Mar 31;501:187-199
Cancer letters 2021 Mar 31;501:187-199
Construction of PD1/CD28 chimeric-switch receptor enhances anti-tumor ability of c-Met CAR-T in gastric cancer.
Chen C, Gu YM, Zhang F, Zhang ZC, Zhang YT, He YD, Wang L, Zhou N, Tang FT, Liu HJ, Li YM
Oncoimmunology 2021 Mar 31;10(1):1901434
Oncoimmunology 2021 Mar 31;10(1):1901434
Selenite Inhibits Notch Signaling in Cells and Mice.
Powers M, Liu L, Deemer D, Chen S, Scholl A, Yoshinaga M, Liu Z
International journal of molecular sciences 2021 Mar 3;22(5)
International journal of molecular sciences 2021 Mar 3;22(5)
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation.
Wei L, Lin Q, Lu Y, Li G, Huang L, Fu Z, Chen R, Zhou Q
Cell death & disease 2021 Mar 29;12(4):334
Cell death & disease 2021 Mar 29;12(4):334
Dietary Marginal and Excess Selenium Increased Triglycerides Deposition, Induced Endoplasmic Reticulum Stress and Differentially Influenced Selenoproteins Expression in the Anterior and Middle Intestines of Yellow Catfish Pelteobagrus fulvidraco.
Zhang DG, Zhao T, Xu XJ, Lv WH, Luo Z
Antioxidants (Basel, Switzerland) 2021 Mar 29;10(4)
Antioxidants (Basel, Switzerland) 2021 Mar 29;10(4)
Inhibition of chikusetsusaponin IVa on inflammatory responses in RAW264.7 cell line via MAPK pathway.
Xu G, Lei H, Yuan Q, Chen H, Su J
Zeitschrift fur Naturforschung. C, Journal of biosciences 2021 Mar 26;76(3-4):103-110
Zeitschrift fur Naturforschung. C, Journal of biosciences 2021 Mar 26;76(3-4):103-110
Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.
Chen Y, Xu T, Li M, Li C, Ma Y, Chen G, Sun Y, Zheng H, Wu G, Liao W, Liao Y, Chen Y, Bin J
Clinical science (London, England : 1979) 2021 Mar 26;135(6):811-828
Clinical science (London, England : 1979) 2021 Mar 26;135(6):811-828
A nuclear export sequence promotes CRM1-dependent targeting of the nucleoporin Nup214 to the nuclear pore complex.
Hamed M, Caspar B, Port SA, Kehlenbach RH
Journal of cell science 2021 Mar 26;134(6)
Journal of cell science 2021 Mar 26;134(6)
Silencing long non-coding RNA MIAT ameliorates myocardial dysfunction induced by myocardial infarction via MIAT/miR-10a-5p/EGR2 axis.
Cao X, Ma Q, Wang B, Qian Q, Liu N, Liu T, Dong X
Aging 2021 Mar 26;13(8):11188-11206
Aging 2021 Mar 26;13(8):11188-11206
Localization of the WD repeat-containing protein 5 to the Virion Assembly Compartment Facilitates Human Cytomegalovirus Assembly.
Yang B, Yao Y, Wu H, Yang H, Ma XH, Li D, Wang XZ, Huang SN, Jiang X, Cheng S, Sun JY, Huang ZL, Zhao C, McVoy MA, Ahn JH, Zeng WB, Britt WJ, Gong S, Luo MH
Journal of virology 2021 Mar 25;95(8)
Journal of virology 2021 Mar 25;95(8)
Long non-coding RNA LNC_000641 regulates pseudorabies virus replication.
Fang L, Gao Y, Liu X, Bai J, Jiang P, Wang X
Veterinary research 2021 Mar 25;52(1):52
Veterinary research 2021 Mar 25;52(1):52
RNAi-mediated silencing of Trichinella spiralis glutaminase results in reduced muscle larval infectivity.
Gao Y, Meng X, Yang X, Meng S, Han C, Li X, Wang S, Li W, Song M
Veterinary research 2021 Mar 25;52(1):51
Veterinary research 2021 Mar 25;52(1):51
A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating β-TrCP E3 Ubiquitin Ligase.
Peng T, Wonganan O, Zhang Z, Yu J, Xi R, Cao Y, Suksamrarn A, Zhang G, Wang F
International journal of molecular sciences 2021 Mar 25;22(7)
International journal of molecular sciences 2021 Mar 25;22(7)
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase.
Liang RJ, Taylor S, Nahiyaan N, Song J, Murphy CJ, Dantas E, Cheng S, Hsu TW, Ramsamooj S, Grover R, Hwang SK, Ngo B, Cantley LC, Rhee KY, Goncalves MD
Cancer & metabolism 2021 Mar 24;9(1):12
Cancer & metabolism 2021 Mar 24;9(1):12
A Unique Anti-Cancer 3-Styrylchromone Suppresses Inflammatory Response via HMGB1-RAGE Signaling.
Abe H, Okazawa M, Oyama T, Yamazaki H, Yoshimori A, Kamiya T, Tsukimoto M, Takao K, Sugita Y, Sakagami H, Abe T, Tanuma SI
Medicines (Basel, Switzerland) 2021 Mar 24;8(4)
Medicines (Basel, Switzerland) 2021 Mar 24;8(4)
FGF1(ΔHBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Wang D, Yin Y, Wang S, Zhao T, Gong F, Zhao Y, Wang B, Huang Y, Cheng Z, Zhu G, Wang Z, Wang Y, Ren J, Liang G, Li X, Huang Z
Signal transduction and targeted therapy 2021 Mar 24;6(1):133
Signal transduction and targeted therapy 2021 Mar 24;6(1):133
Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirus.
Li S, Liu W, Chen Y, Wang L, An W, An X, Song L, Tong Y, Fan H, Lu C
Briefings in bioinformatics 2021 Mar 22;22(2):1378-1386
Briefings in bioinformatics 2021 Mar 22;22(2):1378-1386
SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis.
Shangguan X, He J, Ma Z, Zhang W, Ji Y, Shen K, Yue Z, Li W, Xin Z, Zheng Q, Cao Y, Pan J, Dong B, Cheng J, Wang Q, Xue W
Nature communications 2021 Mar 22;12(1):1812
Nature communications 2021 Mar 22;12(1):1812
Structure of the catalytic core of the Integrator complex.
Pfleiderer MM, Galej WP
Molecular cell 2021 Mar 18;81(6):1246-1259.e8
Molecular cell 2021 Mar 18;81(6):1246-1259.e8
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model.
Zhao D, Pan Y, Yu N, Bai Y, Ma R, Mo F, Zuo J, Chen B, Jia Q, Zhang D, Liu J, Jiang G, Gao S
Royal Society open science 2021 Mar 17;8(3):200974
Royal Society open science 2021 Mar 17;8(3):200974
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Zhang S, Shao Z, Liu X, Hou M, Cheng F, Lei D, Yuan H
Cell death discovery 2021 Mar 15;7(1):49
Cell death discovery 2021 Mar 15;7(1):49
Clock knockdown attenuated reactive oxygen species-mediated senescence of chondrocytes through restoring autophagic flux.
Zhong J, Wang B, Wu B, Shang J, Jiang N, Cui A, Chen Y, Xu X, Lu H
Life sciences 2021 Mar 15;269:119036
Life sciences 2021 Mar 15;269:119036
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Zhang X, Xia H, Wang J, Leng R, Zhou X, Gao Q, He K, Liu D, Huang B
Food & function 2021 Mar 15;12(5):2044-2057
Food & function 2021 Mar 15;12(5):2044-2057
SOCS6 promotes radiosensitivity and decreases cancer cell stemness in esophageal squamous cell carcinoma by regulating c-Kit ubiquitylation.
Sun X, Sun Y, Li J, Zhao X, Shi X, Gong T, Pan S, Zheng Z, Zhang X
Cancer cell international 2021 Mar 12;21(1):165
Cancer cell international 2021 Mar 12;21(1):165
Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.
Xue D, Zhou X, Qiu J
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):98-109
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):98-109
Clock gene Bmal1 controls diurnal rhythms in expression and activity of intestinal carboxylesterase 1.
Chen X, Yu F, Guo X, Su C, Li SS, Wu B
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):52-59
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):52-59
Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.
Su W, Zhu S, Chen K, Yang H, Tian M, Fu Q, Shi G, Feng S, Ren D, Jin X, Yang C
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):88
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):88
Jinfukang regulates integrin/Src pathway and anoikis mediating circulating lung cancer cells migration.
Que ZJ, Yang Y, Liu HT, Shang-Guan WJ, Yu P, Zhu LH, Li HG, Liu HM, Tian JH
Journal of ethnopharmacology 2021 Mar 1;267:113473
Journal of ethnopharmacology 2021 Mar 1;267:113473
A robust platform for expansion and genome editing of primary human natural killer cells.
Huang RS, Lai MC, Shih HA, Lin S
The Journal of experimental medicine 2021 Mar 1;218(3)
The Journal of experimental medicine 2021 Mar 1;218(3)
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817
Food & function 2021 Mar 1;12(4):1803-1817
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation.
Zhang J, Wang C, Wang H, Li X, Xu J, Yu K
International immunopharmacology 2021 Jun;95:107529
International immunopharmacology 2021 Jun;95:107529
Alpinetin protects against hepatic ischemia/reperfusion injury in mice by inhibiting the NF-κB/MAPK signaling pathways.
Pan J, Chen S, Guo W, Cao S, Shi X, Zhang J, Zhang H, Zhang S
International immunopharmacology 2021 Jun;95:107527
International immunopharmacology 2021 Jun;95:107527
Deciphering the synergistic network regulation of active components from SiNiSan against irritable bowel syndrome via a comprehensive strategy: Combined effects of synephrine, paeoniflorin and naringin.
Cai T, Wang X, Li B, Xiong F, Wu H, Yang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jun;86:153527
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jun;86:153527
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1.
Liu H, Qin H, Zhou Y, Yuan Y, Liu Y, Chen Y, Yang Y, Ni H, Xi T, Zheng L
Molecular carcinogenesis 2021 Jun;60(6):413-426
Molecular carcinogenesis 2021 Jun;60(6):413-426
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
Liu Y, Sun B, Zhang S, Li J, Qi J, Bai C, Zhang J, Liang S
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
ODAM promotes junctional epithelium-related gene expression via activation of WNT1 signaling pathway in an ameloblast-like cell line ALC.
Song D, Yang S, Tan T, Wang R, Ma Z, Wang Y, Wang L
Journal of periodontal research 2021 Jun;56(3):482-491
Journal of periodontal research 2021 Jun;56(3):482-491
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Chen L, Mei G, Jiang C, Cheng X, Li D, Zhao Y, Chen H, Wan C, Yao P, Gao C, Tang Y
Cell proliferation 2021 Jun;54(6):e13052
Cell proliferation 2021 Jun;54(6):e13052
Acetylation-stabilized chloride intracellular channel 1 exerts a tumor-promoting effect on cervical cancer cells by activating NF-κB.
Wang W, Li X, Xu Y, Guo W, Yu H, Zhang L, Wang Y, Chen X
Cellular oncology (Dordrecht, Netherlands) 2021 Jun;44(3):557-568
Cellular oncology (Dordrecht, Netherlands) 2021 Jun;44(3):557-568
Targeted inhibition of calpain in mitochondria alleviates oxidative stress-induced myocardial injury.
Zheng D, Cao T, Zhang LL, Fan GC, Qiu J, Peng TQ
Acta pharmacologica Sinica 2021 Jun;42(6):909-920
Acta pharmacologica Sinica 2021 Jun;42(6):909-920
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
Wang S, Yi M, Zhang X, Zhang T, Jiang L, Cao L, Zhou Y, Fang X
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
Generation of A Stable GFP-reporter Zika Virus System for High-throughput Screening of Zika Virus Inhibitors.
Zhang JW, Wang H, Liu J, Ma L, Hua RH, Bu ZG
Virologica Sinica 2021 Jun;36(3):476-489
Virologica Sinica 2021 Jun;36(3):476-489
A novel nonsense variant in MT-CO3 causes MELAS syndrome.
Wang W, Sun Y, Lin Y, Xu X, Zhao D, Ji K, Li W, Zhao Y, Yan C
Neuromuscular disorders : NMD 2021 Jun;31(6):558-565
Neuromuscular disorders : NMD 2021 Jun;31(6):558-565
Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives.
Li X, Wang X, Miao L, Liu Y, Lin X, Guo Y, Yuan R, Tian H
Journal of cellular and molecular medicine 2021 Jun;25(12):5470-5485
Journal of cellular and molecular medicine 2021 Jun;25(12):5470-5485
Dihydroartemisinin prompts amplification of photodynamic therapy-induced reactive oxygen species to exhaust Na/H exchanger 1-mediated glioma cells invasion and migration.
Hou K, Liu J, Du J, Mi S, Ma S, Ba Y, Ji H, Li B, Hu S
Journal of photochemistry and photobiology. B, Biology 2021 Jun;219:112192
Journal of photochemistry and photobiology. B, Biology 2021 Jun;219:112192
Transforming growth factor-β1-induced podocyte injury is associated with increased microRNA-155 expression, enhanced inflammatory responses and MAPK pathway activation.
Zheng X, Zhong Q, Lin X, Gu X, Ling X, Liang Z, Qin Q, Du X
Experimental and therapeutic medicine 2021 Jun;21(6):620
Experimental and therapeutic medicine 2021 Jun;21(6):620
IGF2BP2 knockdown inhibits LPS-induced pyroptosis in BEAS-2B cells by targeting caspase 4, a crucial molecule of the non-canonical pyroptosis pathway.
Wang J, Yuan X, Ding N
Experimental and therapeutic medicine 2021 Jun;21(6):593
Experimental and therapeutic medicine 2021 Jun;21(6):593
MicroRNA-133a-3p suppresses malignant behavior of non-small cell lung cancer cells by negatively regulating ERBB2.
Xu Y, Zhang L, Xia L, Zhu X
Oncology letters 2021 Jun;21(6):457
Oncology letters 2021 Jun;21(6):457
PCTP contributes to human platelet activation by enhancing dense granule secretion.
Abraham S, Ma L, Kong X, Askari S, Edelstein LC, McKenzie SE
Thrombosis research 2021 Jun;202:67-73
Thrombosis research 2021 Jun;202:67-73
TGF-β1-activated cancer-associated fibroblasts promote breast cancer invasion, metastasis and epithelial-mesenchymal transition by autophagy or overexpression of FAP-α.
Huang M, Fu M, Wang J, Xia C, Zhang H, Xiong Y, He J, Liu J, Liu B, Pan S, Liu F
Biochemical pharmacology 2021 Jun;188:114527
Biochemical pharmacology 2021 Jun;188:114527
Shengxuening Extracted from Silkworm Excrement Mitigates Myelosuppression via SCF-Mediated JAK2/STAT3 Signaling.
Ding L, Tan Y, Xu L, Jin Y, Liu Y, Tu H, Zhang D, Wu B, Chen Y, Shen H, Liu L, Huang T, Zhou F
Chemistry & biodiversity 2021 Jun;18(6):e2100139
Chemistry & biodiversity 2021 Jun;18(6):e2100139
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Li J, Sun BX, Wang DL, Liu Y, Qi JJ, Nie XW, Bai CY, Zhang JB, Liang S
Theriogenology 2021 Jun;167:67-76
Theriogenology 2021 Jun;167:67-76
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Zhou L, Zhang C, Yang X, Liu L, Hu J, Hou Y, Tao H, Sugimura H, Chen Z, Wang L, Chen K
Clinical and translational medicine 2021 Jun;11(6):e449
Clinical and translational medicine 2021 Jun;11(6):e449
COL5A1 Variants Cause Aortic Dissection by Activating TGF-β-Signaling Pathway.
Chen P, Yu B, Li Z, Chen Y, Sun Y, Wang DW
Journal of the American Heart Association 2021 Jun;10(11):e019276
Journal of the American Heart Association 2021 Jun;10(11):e019276
Niclosamide ethanolamine ameliorates diabetes-related muscle wasting by inhibiting autophagy.
Cai Y, Zhan H, Weng W, Wang Y, Han P, Yu X, Shao M, Sun H
Skeletal muscle 2021 Jun 9;11(1):15
Skeletal muscle 2021 Jun 9;11(1):15
Expression of the ACE2 virus entry protein in the nervus terminalis reveals the potential for an alternative route to brain infection in COVID-19.
Bilinska K, von Bartheld CS, Butowt R
bioRxiv : the preprint server for biology 2021 Jun 7;
bioRxiv : the preprint server for biology 2021 Jun 7;
Expression of deubiquitinases in human gingiva and cultured human gingival fibroblasts.
Fu YW, Xu HZ
BMC oral health 2021 Jun 6;21(1):290
BMC oral health 2021 Jun 6;21(1):290
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
Liu W, Wang Y, Xie Y, Dai T, Fan M, Li C, Zou Y
Cell death discovery 2021 Jun 5;7(1):136
Cell death discovery 2021 Jun 5;7(1):136
NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving.
Pu ZQ, Yu TF, Liu D, Jin CW, Sadiq E, Qiao X, Li X, Chen Y, Zhang J, Tian M, Li S, Zhao RX, Wang XD
Cell death discovery 2021 Jun 4;7(1):133
Cell death discovery 2021 Jun 4;7(1):133
CircMAPK1 promotes the proliferation and migration of vascular smooth muscle cells through miR-22-3p/ methyl-CpG binding protein 2 axis.
Fu X, Niu T, Yang T, Li X
Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 Jun 30;31(7):2189-2198
Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 Jun 30;31(7):2189-2198
STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose.
Yang X, Bao M, Fang Y, Yu X, Ji J, Ding X
Journal of translational medicine 2021 Jun 30;19(1):283
Journal of translational medicine 2021 Jun 30;19(1):283
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.
Meng B, Kemp SA, Papa G, Datir R, Ferreira IATM, Marelli S, Harvey WT, Lytras S, Mohamed A, Gallo G, Thakur N, Collier DA, Mlcochova P, COVID-19 Genomics UK (COG-UK) Consortium, Duncan LM, Carabelli AM, Kenyon JC, Lever AM, De Marco A, Saliba C, Culap K, Cameroni E, Matheson NJ, Piccoli L, Corti D, James LC, Robertson DL, Bailey D, Gupta RK
Cell reports 2021 Jun 29;35(13):109292
Cell reports 2021 Jun 29;35(13):109292
Melatonin Ameliorates the Toxicity Induced by Deoxynivalenol in Murine Ovary Granulosa Cells by Antioxidative and Anti-Inflammatory Effects.
Fan H, Wang S, Wang H, Sun M, Wu S, Bao W
Antioxidants (Basel, Switzerland) 2021 Jun 29;10(7)
Antioxidants (Basel, Switzerland) 2021 Jun 29;10(7)
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146
Journal of neuroinflammation 2021 Jun 28;18(1):146
Long noncoding RNA LINC00284 facilitates cell proliferation in papillary thyroid cancer via impairing miR-3127-5p targeted E2F7 suppression.
Zhou B, Ge Y, Shao Q, Yang L, Chen X, Jiang G
Cell death discovery 2021 Jun 26;7(1):156
Cell death discovery 2021 Jun 26;7(1):156
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease.
Ning XL, Li YZ, Huo C, Deng J, Gao C, Zhu KR, Wang M, Wu YX, Yu JL, Ren YL, Luo ZY, Li G, Chen Y, Wang SY, Peng C, Yang LL, Wang ZY, Wu Y, Qian S, Li GB
Journal of medicinal chemistry 2021 Jun 24;64(12):8303-8332
Journal of medicinal chemistry 2021 Jun 24;64(12):8303-8332
Apple Polyphenol Extract Improves High-Fat Diet-Induced Hepatic Steatosis by Regulating Bile Acid Synthesis and Gut Microbiota in C57BL/6 Male Mice.
Li D, Cui Y, Wang X, Liu F, Li X
Journal of agricultural and food chemistry 2021 Jun 23;69(24):6829-6841
Journal of agricultural and food chemistry 2021 Jun 23;69(24):6829-6841
Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection.
Zhao J, Wan S, Sun N, Sun P, Sun Y, Khan A, Guo J, Zheng X, Fan K, Yin W, Li H
Veterinary research 2021 Jun 23;52(1):93
Veterinary research 2021 Jun 23;52(1):93
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.
Shen Y, Tang K, Chen D, Hong M, Sun F, Wang S, Ke Y, Wu T, Sun R, Qian J, Du Y
Cell reports 2021 Jun 22;35(12):109272
Cell reports 2021 Jun 22;35(12):109272
Mobile element insertions and associated structural variants in longitudinal breast cancer samples.
Steely CJ, Russell KL, Feusier JE, Qiao Y, Tavtigian SV, Marth G, Jorde LB
Scientific reports 2021 Jun 22;11(1):13020
Scientific reports 2021 Jun 22;11(1):13020
Human amnion-derived mesenchymal stem cells improved the reproductive function of age-related diminished ovarian reserve in mice through Ampk/FoxO3a signaling pathway.
Liu H, Jiang C, La B, Cao M, Ning S, Zhou J, Yan Z, Li C, Cui Y, Ma X, Wang M, Chen L, Yu Y, Chen F, Zhang Y, Wu H, Liu J, Qin L
Stem cell research & therapy 2021 Jun 2;12(1):317
Stem cell research & therapy 2021 Jun 2;12(1):317
DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury.
Bao Y, Bai M, Zhu H, Yuan Y, Wang Y, Zhang Y, Wang J, Xie X, Yao X, Mao J, Fu X, Chen J, Yang Y, Lin W
Cell death discovery 2021 Jun 17;7(1):167
Cell death discovery 2021 Jun 17;7(1):167
Hollow PtCo alloy nanospheres as a high-Z and oxygen generating nanozyme for radiotherapy enhancement in non-small cell lung cancer.
Li S, Sun W, Luo Y, Gao Y, Jiang X, Yuan C, Han L, Cao K, Gong Y, Xie C
Journal of materials chemistry. B 2021 Jun 16;9(23):4643-4653
Journal of materials chemistry. B 2021 Jun 16;9(23):4643-4653
NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.
Zhao X, Jiang L, Hu D, Tang Y, Zhao G, Du X, Luo S, Tang W
Experimental cell research 2021 Jun 15;403(2):112614
Experimental cell research 2021 Jun 15;403(2):112614
Chlorogenic Acid Promotes Osteogenic Differentiation of Human Dental Pulp Stem Cells Through Wnt Signaling.
Hu X, Wang L, He Y, Wei M, Yan H, Zhu H
Stem cells and development 2021 Jun 15;30(12):641-650
Stem cells and development 2021 Jun 15;30(12):641-650
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation.
Brazzo JA, Biber JC, Nimmer E, Heo Y, Ying L, Zhao R, Lee K, Krause M, Bae Y
Journal of cell science 2021 Jun 15;134(12)
Journal of cell science 2021 Jun 15;134(12)
Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.
Hsu JC, Laurent-Rolle M, Pawlak JB, Wilen CB, Cresswell P
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 15;118(24)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 15;118(24)
Small extracellular ring domain is necessary for CD82/KAI1'anti-metastasis function.
Ma X, He X, Wang C, Huang X, Li Y, Ma K
Biochemical and biophysical research communications 2021 Jun 11;557:110-116
Biochemical and biophysical research communications 2021 Jun 11;557:110-116
PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.
Wang W, Wei J, Zhang H, Zheng X, Zhou H, Luo Y, Yang J, Deng Q, Huang S, Fu Z
Cell death & disease 2021 Jun 11;12(6):605
Cell death & disease 2021 Jun 11;12(6):605
Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.
Lin Z, Zhao C, Lei Z, Zhang Y, Huang R, Lin B, Dong Y, Zhang H, Li J, Li X
Stem cell research & therapy 2021 Jun 10;12(1):341
Stem cell research & therapy 2021 Jun 10;12(1):341
Tryptanthrin exerts anti-breast cancer effects both in vitro and in vivo through modulating the inflammatory tumor microenvironment.
Zeng Q, Luo C, Cho J, Lai D, Shen X, Zhang X, Zhou W
Acta pharmaceutica (Zagreb, Croatia) 2021 Jun 1;71(2):245-266
Acta pharmaceutica (Zagreb, Croatia) 2021 Jun 1;71(2):245-266
Mitochondrial DNA enables AIM2 inflammasome activation and hepatocyte pyroptosis in nonalcoholic fatty liver disease.
Xu L, Zhou J, Che J, Wang H, Yang W, Zhou W, Zhao H
American journal of physiology. Gastrointestinal and liver physiology 2021 Jun 1;320(6):G1034-G1044
American journal of physiology. Gastrointestinal and liver physiology 2021 Jun 1;320(6):G1034-G1044
Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis.
Liu W, Peng L, Tian W, Li Y, Zhang P, Sun K, Yang Y, Li X, Li G, Zhu X
Disease models & mechanisms 2021 Jun 1;14(6)
Disease models & mechanisms 2021 Jun 1;14(6)
Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2-STAT3 pathway.
Yang S, Song Y, Wang Q, Liu Y, Wu Z, Duan X, Zhang Y, Bi X, Geng Y, Chen S, Zhu C
Scientific reports 2021 Jun 1;11(1):11491
Scientific reports 2021 Jun 1;11(1):11491
Modeling Cone/Cone-Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina.
Wang Y, Li X, Yu Y, Liang J, Liu Y, Chen Y, Bai X, Chen J, Wang F, Luo X, Sun X
Translational vision science & technology 2021 Jun 1;10(7):25
Translational vision science & technology 2021 Jun 1;10(7):25
Lipopolysaccharide/D-galactosamine-induced acute liver injury could be attenuated by dopamine receptor agonist rotigotine via regulating NF-κB signaling pathway.
Yue S, Wang T, Yang Y, Fan Y, Zhou L, Li M, Fu F
International immunopharmacology 2021 Jul;96:107798
International immunopharmacology 2021 Jul;96:107798
Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis.
Zhu Z, Hu R, Li J, Xing X, Chen J, Zhou Q, Sun J
International immunopharmacology 2021 Jul;96:107660
International immunopharmacology 2021 Jul;96:107660
MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer.
Wu SY, Xiao Y, Wei JL, Xu XE, Jin X, Hu X, Li DQ, Jiang YZ, Shao ZM
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
Low androgen status inhibits erectile function by increasing pyroptosis in rat corpus cavernosum.
Chen ZB, Li G, Lin H, Jiang J, Jiang R
Andrology 2021 Jul;9(4):1264-1274
Andrology 2021 Jul;9(4):1264-1274
Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation.
Luo S, Ai Y, Xiao S, Wang B, Wang Y
Annals of translational medicine 2021 Jul;9(13):1087
Annals of translational medicine 2021 Jul;9(13):1087
Apoptotic caspases suppress Mycobacterium bovis-induced IFN-β production in murine macrophage.
Song Y, Dong Y, Liao Y, Liang Z, Yao J, Zhou X
The Journal of infection 2021 Jul;83(1):61-68
The Journal of infection 2021 Jul;83(1):61-68
Knockdown of USP9X reverses cisplatin resistance by decreasing β-catenin expression in nasopharyngeal carcinoma cells.
Lu WX, Gan GS, Yang B
Neoplasma 2021 Jul;68(4):810-822
Neoplasma 2021 Jul;68(4):810-822
MDM2 induces EMT via the B‑Raf signaling pathway through 14‑3‑3.
Ou M, Xu X, Chen Y, Li L, Zhang L, Liao Y, Sun W, Quach C, Feng J, Tang L
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
Ou W, Liang Y, Qin Y, Wu W, Xie M, Zhang Y, Zhang Y, Ji L, Yu H, Li T
Redox biology 2021 Jul;43:101994
Redox biology 2021 Jul;43:101994
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
Zhao X, Sun Y, Sun X, Li J, Shi X, Liang Z, Ma Y, Zhang X
DNA and cell biology 2021 Jul;40(7):895-905
DNA and cell biology 2021 Jul;40(7):895-905
High-fat diet exacerbates lead-induced blood-brain barrier disruption by disrupting tight junction integrity.
Li C, Shi L, Wang Y, Peng C, Wu L, Zhang Y, Du Z
Environmental toxicology 2021 Jul;36(7):1412-1421
Environmental toxicology 2021 Jul;36(7):1412-1421
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Chen W, Yu X, Wu Y, Tang J, Yu Q, Lv X, Zha Z, Hu B, Li X, Chen J, Ma L, Workman JL, Li S
Nature metabolism 2021 Jul;3(7):983-1000
Nature metabolism 2021 Jul;3(7):983-1000
Biliary excretion of excess iron in mice requires hepatocyte iron import by Slc39a14.
Prajapati M, Conboy HL, Hojyo S, Fukada T, Budnik B, Bartnikas TB
The Journal of biological chemistry 2021 Jul;297(1):100835
The Journal of biological chemistry 2021 Jul;297(1):100835
The antiviral enzyme viperin inhibits cholesterol biosynthesis.
Grunkemeyer TJ, Ghosh S, Patel AM, Sajja K, Windak J, Basrur V, Kim Y, Nesvizhskii AI, Kennedy RT, Marsh ENG
The Journal of biological chemistry 2021 Jul;297(1):100824
The Journal of biological chemistry 2021 Jul;297(1):100824
The stabilization of yes-associated protein by TGFβ-activated kinase 1 regulates the self-renewal and oncogenesis of gastric cancer stem cells.
Wang G, Sun Q, Zhu H, Bi Y, Zhu H, Xu A
Journal of cellular and molecular medicine 2021 Jul;25(14):6584-6601
Journal of cellular and molecular medicine 2021 Jul;25(14):6584-6601
MACF1 alleviates aging-related osteoporosis via HES1.
Yin C, Tian Y, Hu L, Yu Y, Wu Z, Zhang Y, Wang X, Miao Z, Qian A
Journal of cellular and molecular medicine 2021 Jul;25(13):6242-6257
Journal of cellular and molecular medicine 2021 Jul;25(13):6242-6257
CDCA2 promotes tumorigenesis and induces radioresistance in oesophageal squamous cell carcinoma cells.
Xu B, Chen H, Xu Z, Yao X, Sun X, Cheng H
Molecular medicine reports 2021 Jul;24(1)
Molecular medicine reports 2021 Jul;24(1)
MFGE8 mitigates brain injury in a rat model of SAH by maintaining vascular endothelial integrity via TIGβ5/PI3K/CXCL12 signaling.
Wang J, Wang Y, Zuo Y, Duan J, Pan A, Li JM, Yan XX, Liu F
Experimental brain research 2021 Jul;239(7):2193-2205
Experimental brain research 2021 Jul;239(7):2193-2205
CXCL6 fuels the growth and metastases of esophageal squamous cell carcinoma cells both in vitro and in vivo through upregulation of PD-L1 via activation of STAT3 pathway.
Zheng S, Shen T, Liu Q, Liu T, Tuerxun A, Zhang Q, Yang L, Han X, Lu X
Journal of cellular physiology 2021 Jul;236(7):5373-5386
Journal of cellular physiology 2021 Jul;236(7):5373-5386
The alterations of miRNA and mRNA expression profile and their integration analysis induced by silica nanoparticles in spermatocyte cells.
Zhou G, Ren L, Yin H, Liu J, Li X, Wang J, Li Y, Sang Y, Zhao Y, Zhou X, Sun Z
NanoImpact 2021 Jul;23:100348
NanoImpact 2021 Jul;23:100348
Hirsutanol A inhibits T-acute lymphocytic leukemia Jurkat cell viability through cell cycle arrest and p53-dependent induction of apoptosis.
Zhong F, Yang Y, Ren D, Long S, Qin X, Liu J, Zeng Y, Lan W, Ma W, Liu W
Experimental and therapeutic medicine 2021 Jul;22(1):741
Experimental and therapeutic medicine 2021 Jul;22(1):741
Dihydroartemisinin inhibits endothelial cell migration via the TGF-β1/ALK5/SMAD2 signaling pathway.
Guo L, Wen X, Hou Y, Sun R, Zhang L, Liu F, Liu J
Experimental and therapeutic medicine 2021 Jul;22(1):709
Experimental and therapeutic medicine 2021 Jul;22(1):709
MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and in vitro experiments.
Li M, Zhou L, Li S, Fang L, Yang L, Wu X, Yang C, Bao Y, Lan S, Tong Z, Zheng S, Tang B, Zeng E, Xie S, Chen C, Hong T
Oncology letters 2021 Jul;22(1):536
Oncology letters 2021 Jul;22(1):536
miR-590-5p targets RMND5A and promotes migration in pancreatic adenocarcinoma cell lines.
Chen S, Chen Y, Wen Y, Cai W, Zhu P, Yuan W, Li Y, Fan X, Wan Y, Li F, Zhuang J, Jiang Z, Wu X, Wang Y
Oncology letters 2021 Jul;22(1):532
Oncology letters 2021 Jul;22(1):532
Entry receptor bias in evolutionarily distant HSV-1 clinical strains drives divergent ocular and nervous system pathologies.
Koujah L, Allaham M, Patil CD, Ames JM, Suryawanshi RK, Yadavalli T, Agelidis A, Mun C, Surenkhuu B, Jain S, Shukla D
The ocular surface 2021 Jul;21:238-249
The ocular surface 2021 Jul;21:238-249
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
Liu J, Zhang N, Zhang M, Yin H, Zhang X, Wang X, Wang X, Zhao Y
Experimental eye research 2021 Jul;208:108595
Experimental eye research 2021 Jul;208:108595
miR-665 inhibits epithelial-to-mesenchymal transition in bladder cancer via the SMAD3/SNAIL axis.
Wang W, Ying Y, Xie H, Li J, Ma X, He L, Xu M, Chen S, Shen H, Zheng X, Liu B, Wang X, Xie L
Cell cycle (Georgetown, Tex.) 2021 Jul;20(13):1242-1252
Cell cycle (Georgetown, Tex.) 2021 Jul;20(13):1242-1252
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
Zhang W, Yang X, Chen L, Liu YY, Venkatarangan V, Reist L, Hanson P, Xu H, Wang Y, Li M
PLoS biology 2021 Jul;19(7):e3001361
PLoS biology 2021 Jul;19(7):e3001361
Metabolomic profiling of single enlarged lysosomes.
Zhu H, Li Q, Liao T, Yin X, Chen Q, Wang Z, Dai M, Yi L, Ge S, Miao C, Zeng W, Qu L, Ju Z, Huang G, Cang C, Xiong W
Nature methods 2021 Jul;18(7):788-798
Nature methods 2021 Jul;18(7):788-798
Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis.
Jia H, Liu M, Wang X, Jiang Q, Wang S, Santhanam RK, Lv C, Zhao Q, Lu J
Pharmacological research 2021 Jul;169:105686
Pharmacological research 2021 Jul;169:105686
Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.
Jia X, Zhang A, Li Z, Peng X, Tian X, Gao F
Journal of neurochemistry 2021 Jul;158(2):373-390
Journal of neurochemistry 2021 Jul;158(2):373-390
A genetic variant conferred high expression of CAV2 promotes pancreatic cancer progression and associates with poor prognosis.
Zhu Y, Tian J, Peng X, Wang X, Yang N, Ying P, Wang H, Li B, Li Y, Zhang M, Cai Y, Lu Z, Niu S, Li Y, Zhong R, Chang J, Miao X
European journal of cancer (Oxford, England : 1990) 2021 Jul;151:94-105
European journal of cancer (Oxford, England : 1990) 2021 Jul;151:94-105
Long noncoding RNA IL6-AS1 is highly expressed in chronic obstructive pulmonary disease and is associated with interleukin 6 by targeting miR-149-5p and early B-cell factor 1.
Yi E, Zhang J, Zheng M, Zhang Y, Liang C, Hao B, Hong W, Lin B, Pu J, Lin Z, Huang P, Li B, Zhou Y, Ran P
Clinical and translational medicine 2021 Jul;11(7):e479
Clinical and translational medicine 2021 Jul;11(7):e479
Levosimendan in rats decreases acute kidney injury after cardiopulmonary resuscitation by improving mitochondrial dysfunction.
Zhao L, Tian L, Wang S, Yang W, Lu X, Zhu C
Translational andrology and urology 2021 Jul;10(7):3010-3020
Translational andrology and urology 2021 Jul;10(7):3010-3020
Activation of Interleukin-1β Release and Pyroptosis by Transmissible Gastroenteritis Virus Is Dependent on the NOD-Like Receptor Protein 3 Inflammasome in Porcine Intestinal Epithelial Cell Line.
Wei G, Luo S, Wu W, Hu J, Zhou R
Viral immunology 2021 Jul-Aug;34(6):401-409
Viral immunology 2021 Jul-Aug;34(6):401-409
Discovery of Potent Phosphodiesterase-9 Inhibitors for the Treatment of Hepatic Fibrosis.
Wu Y, Wang Q, Jiang MY, Huang YY, Zhu Z, Han C, Tian YJ, Zhang B, Luo HB
Journal of medicinal chemistry 2021 Jul 8;64(13):9537-9549
Journal of medicinal chemistry 2021 Jul 8;64(13):9537-9549
7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis.
Xue F, Zhao Z, Gu Y, Han J, Ye K, Zhang Y
eLife 2021 Jul 6;10
eLife 2021 Jul 6;10
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Liu J, Jin Y, Wang B, Wang Y, Zuo S, Zhang J
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3.
Li HN, Yang QQ, Wang WT, Tian X, Feng F, Zhang ST, Xia YT, Wang JX, Zou YW, Wang JY, Zeng XY
Journal of neuroinflammation 2021 Jul 5;18(1):150
Journal of neuroinflammation 2021 Jul 5;18(1):150
Alpha Enolase 1 Ubiquitination and Degradation Mediated by Ehrlichia chaffeensis TRP120 Disrupts Glycolytic Flux and Promotes Infection.
Zhu B, McBride JW
Pathogens (Basel, Switzerland) 2021 Jul 30;10(8)
Pathogens (Basel, Switzerland) 2021 Jul 30;10(8)
Upregulation of ARNTL2 is associated with poor survival and immune infiltration in clear cell renal cell carcinoma.
Wang S, Ma X, Ying Y, Sun J, Yang Z, Li J, Jin K, Wang X, Xie B, Zheng X, Liu B, Xie L
Cancer cell international 2021 Jul 3;21(1):341
Cancer cell international 2021 Jul 3;21(1):341
Obesity increases neuropathic pain via the AMPK-ERK-NOX4 pathway in rats.
Fu CN, Wei H, Gao WS, Song SS, Yue SW, Qu YJ
Aging 2021 Jul 29;13(14):18606-18619
Aging 2021 Jul 29;13(14):18606-18619
EGR2-mediated regulation of m(6)A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization.
Ying Y, Ma X, Fang J, Chen S, Wang W, Li J, Xie H, Wu J, Xie B, Liu B, Wang X, Zheng X, Xie L
Cell death & disease 2021 Jul 29;12(8):750
Cell death & disease 2021 Jul 29;12(8):750
Comprehensive Analysis of Lysine Lactylation in Rice (Oryza sativa) Grains.
Meng X, Baine JM, Yan T, Wang S
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8287-8297
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8287-8297
miR-139-5p mediates the palmitate-induced inhibition of insulin secretion by targeting neuronal pentraxin 1 in INS-1 cells.
Zhang K, Zhang Y, Chen C, Yuan Y, Jiang X, Yuan X, Wang Y
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1017-1026
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):1017-1026
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Luo W, Li J, Li Z, Lin T, Zhang L, Yang W, Mai Y, Liu R, Chen M, Dai C, Yang H, Lu J, Li H, Guan G, Huang M, Liu P, Li Z
Cell death & disease 2021 Jul 26;12(8):738
Cell death & disease 2021 Jul 26;12(8):738
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) and Treadmill Training on Recovery of Motor Function in a Rat Model of Partial Spinal Cord Injury.
Wang P, Yin R, Wang S, Zhou T, Zhang Y, Xiao M, Wang H, Xu G
Medical science monitor : international medical journal of experimental and clinical research 2021 Jul 25;27:e931601
Medical science monitor : international medical journal of experimental and clinical research 2021 Jul 25;27:e931601
MYOC Promotes the Differentiation of C2C12 Cells by Regulation of the TGF-β Signaling Pathways via CAV1.
Zhang Y, Li S, Wen X, Tong H, Li S, Yan Y
Biology 2021 Jul 20;10(7)
Biology 2021 Jul 20;10(7)
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats.
Tan B, Chen J, Qin S, Liao C, Zhang Y, Wang D, Li S, Zhang Z, Zhang P, Xu F
Chemical research in toxicology 2021 Jul 19;34(7):1759-1768
Chemical research in toxicology 2021 Jul 19;34(7):1759-1768
METTL7B is a novel prognostic biomarker of lower-grade glioma based on pan-cancer analysis.
Jiang Z, Yin W, Zhu H, Tan J, Guo Y, Xin Z, Zhou Q, Cao Y, Wu Z, Kuang Y, Li C, Xie D, Huang H, Zhao M, Jiang X, Wang L, Ren C
Cancer cell international 2021 Jul 19;21(1):383
Cancer cell international 2021 Jul 19;21(1):383
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Yang B, Li L, Tong G, Zeng Z, Tan J, Su Z, Liu Z, Lin J, Gao W, Chen J, Zeng S, Wu G, Li L, Zhu S, Liu Q, Lin L
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Tang H, Zhang P, Zeng L, Zhao Y, Xie L, Chen B
Stem cell research & therapy 2021 Jul 16;12(1):409
Stem cell research & therapy 2021 Jul 16;12(1):409
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
He ZY, Huang MT, Cui X, Zhou ST, Wu Y, Zhang PH, Zhou J
Molecular and cellular endocrinology 2021 Jul 15;532:111283
Molecular and cellular endocrinology 2021 Jul 15;532:111283
Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma.
Li Y, Qiao L, Bai Y, Xiao C, Wu J, Gao X, Qiao C, Shi Y, Hou W, Wang J, Xie N, Liu N
Life sciences 2021 Jul 15;277:119592
Life sciences 2021 Jul 15;277:119592
Early-senescent bone marrow mesenchymal stem cells promote C2C12 cell myogenic differentiation by preventing the nuclear translocation of FOXO3.
Che J, Xu C, Wu Y, Jia P, Han Q, Ma Y, Wang X, Du Y, Zheng Y
Life sciences 2021 Jul 15;277:119520
Life sciences 2021 Jul 15;277:119520
Zuojin Pill ameliorates inflammation in indomethacin-induced gastric injury via inhibition of MAPK pathway.
Wei Y, Wang R, Ren S, Liu X, Jing M, Li R, Tong Y, Wen J, Yang T, Wang J, Zhao Y
Journal of ethnopharmacology 2021 Jul 15;275:114103
Journal of ethnopharmacology 2021 Jul 15;275:114103
Retinoblastoma cell-derived exosomes promote angiogenesis of human vesicle endothelial cells through microRNA-92a-3p.
Chen S, Chen X, Luo Q, Liu X, Wang X, Cui Z, He A, He S, Jiang Z, Wu N, Chen P, Yu K, Zhuang J
Cell death & disease 2021 Jul 13;12(7):695
Cell death & disease 2021 Jul 13;12(7):695
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes.
Kutchukian C, Vivas O, Casas M, Jones JG, Tiscione SA, Simó S, Ory DS, Dixon RE, Dickson EJ
The EMBO journal 2021 Jul 1;40(13):e105990
The EMBO journal 2021 Jul 1;40(13):e105990
HMGB1: an important regulator of myeloid differentiation and acute myeloid leukemia as well as a promising therapeutic target.
Liu L, Zhang J, Zhang X, Cheng P, Liu L, Huang Q, Liu H, Ren S, Wei P, Wang C, Dou C, Chen L, Liu X, Zhang H, Chen M
Journal of molecular medicine (Berlin, Germany) 2021 Jan;99(1):107-118
Journal of molecular medicine (Berlin, Germany) 2021 Jan;99(1):107-118
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization.
Ding J, Yang C, Cheng Y, Wang J, Zhang S, Yan S, He F, Yin T, Yang J
International immunopharmacology 2021 Jan;90:106788
International immunopharmacology 2021 Jan;90:106788
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Liu D, Han Y, Liu L, Ren X, Zhang H, Fan S, Qin T, Li L
International journal of oncology 2021 Jan;58(1):100-110
International journal of oncology 2021 Jan;58(1):100-110
Effect of acetate, β-hydroxybutyrate and their interaction on lipogenic gene expression, triglyceride contents and lipid droplet formation in dairy cow mammary epithelial cells.
Ali I, Li C, Li L, Kuang M, Shafiq M, Wang Y, Yang M, Wang G
In vitro cellular & developmental biology. Animal 2021 Jan;57(1):66-75
In vitro cellular & developmental biology. Animal 2021 Jan;57(1):66-75
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Lin J, Deng H, Zhang Y, Zou L, Fu Z, Dai J
Pediatric pulmonology 2021 Jan;56(1):129-137
Pediatric pulmonology 2021 Jan;56(1):129-137
Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis.
He Z, Liao W, Song Q, Li B, Liu J, Xiong Y, Song C, Yang S
International journal of molecular medicine 2021 Jan;47(1):289-301
International journal of molecular medicine 2021 Jan;47(1):289-301
YAP and Wnt3a independently promote AECIIs proliferation and differentiation by increasing nuclear β‑catenin expression in experimental bronchopulmonary dysplasia.
Jia X, Wu B, Huang J, Fan L, Yang M, Xu W
International journal of molecular medicine 2021 Jan;47(1):195-206
International journal of molecular medicine 2021 Jan;47(1):195-206
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
Hu XQ, Tang Y, Ju Y, Zhang XY, Yan JJ, Wang CM, Yang Y, Zhu C, Tang ZX, Zhou Y, Yu G
Clinical and experimental dermatology 2021 Jan;46(1):74-81
Clinical and experimental dermatology 2021 Jan;46(1):74-81
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Chen S, Chen X, Qiu J, Chen P, Han X, Wu Y, Zhuang J, Yang M, Wu C, Wu N, Yang Y, Ge J, Yu K, Zhuang J
Oncology reports 2021 Jan;45(1):278-290
Oncology reports 2021 Jan;45(1):278-290
Microarray expression profile analysis of circular RNAs and their potential regulatory role in bladder carcinoma.
Li S, Zhao Y, Chen X
Oncology reports 2021 Jan;45(1):239-253
Oncology reports 2021 Jan;45(1):239-253
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Lin X, Li Y, Zhang X, Wei Y, Wen S, Lu Z, Huang Q, Wei J
Cell biochemistry and function 2021 Jan;39(1):77-87
Cell biochemistry and function 2021 Jan;39(1):77-87
A rare mutant of OFD1 gene responsible for Joubert syndrome with significant phenotype variation.
Zhang YW, Qu HB, Long N, Leng XY, Liu YQ, Yang Y
Molecular genetics and genomics : MGG 2021 Jan;296(1):33-40
Molecular genetics and genomics : MGG 2021 Jan;296(1):33-40
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.
Zhang J, Chen Y, Chen X, Zhang W, Zhao L, Weng L, Tian H, Wu Z, Tan X, Ge X, Wang P, Fang L
Cell death and differentiation 2021 Jan;28(1):139-155
Cell death and differentiation 2021 Jan;28(1):139-155
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
Sun D, Ding D, Li Q, Xie M, Xu Y, Liu X
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
Upregulation Sestrin2 protects against hydrogen peroxide-induced oxidative damage bovine mammary epithelial cells via a Keap1-Nrf2/ARE pathway.
Chen M, Xi Y, Chen K, Xiao P, Li S, Sun X, Han Z
Journal of cellular physiology 2021 Jan;236(1):392-404
Journal of cellular physiology 2021 Jan;236(1):392-404
MicroRNA‑744‑5p is downregulated in colorectal cancer and targets SEPT2 to suppress the malignant phenotype.
Zhang W, Liao K, Liu D
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
CSN1 facilitates proliferation and migration of hepatocellular carcinoma cells by upregulating cyclin A2 expression.
Fu H, Zhang Y, Chen Y, Chen J, Chen P
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Regulation of ABCG2 expression by Wnt5a through FZD7 in human pancreatic cancer cells.
Zhang Z, Gao S, Xu Y, Zhao C
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Exogenous sodium hydrosulfide protects against high glucose‑induced injury and inflammation in human umbilical vein endothelial cells by inhibiting necroptosis via the p38 MAPK signaling pathway.
Lin J, Li X, Lin Y, Huang Z, Wu W
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
Journal of inorganic biochemistry 2021 Jan;214:111269
Journal of inorganic biochemistry 2021 Jan;214:111269
Naringin attenuates renal interstitial fibrosis by regulating the TGF-β/Smad signaling pathway and inflammation.
Wang R, Wu G, Dai T, Lang Y, Chi Z, Yang S, Dong D
Experimental and therapeutic medicine 2021 Jan;21(1):66
Experimental and therapeutic medicine 2021 Jan;21(1):66
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Wang P, Wang C, Liu C
Oncology letters 2021 Jan;21(1):59
Oncology letters 2021 Jan;21(1):59
Long noncoding RNA AK039312 and AK079370 inhibits bone formation via miR-199b-5p.
Yin C, Tian Y, Yu Y, Li D, Miao Z, Su P, Zhao Y, Wang X, Pei J, Zhang K, Qian A
Pharmacological research 2021 Jan;163:105230
Pharmacological research 2021 Jan;163:105230
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z
Free radical biology & medicine 2021 Jan;162:181-190
Free radical biology & medicine 2021 Jan;162:181-190
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Zhang Y, Han X, Nie G
Nature protocols 2021 Jan;16(1):405-430
Nature protocols 2021 Jan;16(1):405-430
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling.
Xu Y, Wang P, Li M, Wu Z, Li X, Shen J, Xu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111054
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111054
The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
Baade I, Hutten S, Sternburg EL, Pörschke M, Hofweber M, Dormann D, Kehlenbach RH
The Journal of biological chemistry 2021 Jan-Jun;296:100659
The Journal of biological chemistry 2021 Jan-Jun;296:100659
Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice.
Sasaki T, Watanabe Y, Kuboyama A, Oikawa A, Shimizu M, Yamauchi Y, Sato R
The Journal of biological chemistry 2021 Jan-Jun;296:100131
The Journal of biological chemistry 2021 Jan-Jun;296:100131
Clonal Architectures Predict Clinical Outcome in Gastric Adenocarcinoma Based on Genomic Variation, Tumor Evolution, and Heterogeneity.
Ren C, Wu C, Wang N, Lian C, Yang C
Cell transplantation 2021 Jan-Dec;30:963689721989606
Cell transplantation 2021 Jan-Dec;30:963689721989606
Overexpression of ICAT Inhibits the Progression of Colorectal Cancer by Binding with β-Catenin in the Cytoplasm.
Hu J, Wang Z, Chen J, Yu Z, Zhang J, Li W, Lin M, Yang X, Liu H
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211041253
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211041253
S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.
Wang H, Yin M, Ye L, Gao P, Mao X, Tian X, Xu Z, Dai X, Cheng H
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211011961
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211011961
Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization.
Zhou F, Wang X, Han B, Tang X, Liu R, Ji Q, Zhou Z, Zhang L
Molecular pain 2021 Jan-Dec;17:1744806921996520
Molecular pain 2021 Jan-Dec;17:1744806921996520
Suppression of TCAB1 expression induced cellular senescence by lessening proteasomal degradation of p21 in cancer cells.
Niu J, Gao RQ, Cui MT, Zhang CG, Li ST, Cheng S, Ding W
Cancer cell international 2021 Jan 7;21(1):26
Cancer cell international 2021 Jan 7;21(1):26
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Zhang HT, Zeng Q, Wu B, Lu J, Tong KL, Lin J, Liu QY, Xu L, Yang J, Liu X, Liu W, Zhang YF, Lian Q, Liu L, Gao X
Cell death & disease 2021 Jan 6;12(1):21
Cell death & disease 2021 Jan 6;12(1):21
Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension.
Sun X, Zhou M, Wen G, Huang Y, Wu J, Peng L, Jiang W, Yuan H, Lu Y, Cai J
Journal of the American Heart Association 2021 Jan 5;10(1):e016364
Journal of the American Heart Association 2021 Jan 5;10(1):e016364
C1QTNF6 regulates cell proliferation and apoptosis of NSCLC in vitro and in vivo.
Zhang W, Feng G
Bioscience reports 2021 Jan 29;41(1)
Bioscience reports 2021 Jan 29;41(1)
Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation.
Zhang S, Yu X, Zhang Y, Xue X, Yu Q, Zha Z, Gogol M, Workman JL, Li S
Nature communications 2021 Jan 26;12(1):594
Nature communications 2021 Jan 26;12(1):594
Lectin-Mediated Binding of Engineered Lactococcus lactis to Cancer Cells.
Plavec TV, Zahirović A, Zadravec P, Sabotič J, Berlec A
Microorganisms 2021 Jan 22;9(2)
Microorganisms 2021 Jan 22;9(2)
Peptide OM-LV20 exerts neuroprotective effects against cerebral ischemia/reperfusion injury in rats.
Yin S, Yang M, Li Y, Li S, Fu Z, Liu N, Wang Y, Hu Y, Xie C, Shu L, Pang A, Gu Y, Wang Y, Sun J, Yang X
Biochemical and biophysical research communications 2021 Jan 22;537:36-42
Biochemical and biophysical research communications 2021 Jan 22;537:36-42
ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase.
Zhang X, Tang L, Zhang Z
Biochemical and biophysical research communications 2021 Jan 22;537:15-21
Biochemical and biophysical research communications 2021 Jan 22;537:15-21
TGFβ-1 Induced Cross-Linking of the Extracellular Matrix of Primary Human Dermal Fibroblasts.
Semkova ME, Hsuan JJ
International journal of molecular sciences 2021 Jan 20;22(3)
International journal of molecular sciences 2021 Jan 20;22(3)
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Hu Z, Mao C, Wang H, Zhang Z, Zhang S, Luo H, Tang M, Yang J, Yuan Y, Wang Y, Liu Y, Fan L, Zhang Q, Yao D, Liu F, Schisler JC, Shi C, Xu Y
Aging 2021 Jan 2;13(1):1458-1472
Aging 2021 Jan 2;13(1):1458-1472
Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53.
Wang J, Liu D, Sun Z, Ye T, Li J, Zeng B, Zhao Q, Rosie Xing H
Cell death & disease 2021 Jan 19;12(1):98
Cell death & disease 2021 Jan 19;12(1):98
Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer.
Wu S, Luo M, To KKW, Zhang J, Su C, Zhang H, An S, Wang F, Chen D, Fu L
Molecular cancer 2021 Jan 18;20(1):17
Molecular cancer 2021 Jan 18;20(1):17
Stability of Smyd1 in endothelial cells is controlled by PML-dependent SUMOylation upon cytokine stimulation.
Becker S, Steinemann G, Karle W, Roos K, Liem CH, Muralikumar S, Volkamer A, Munz B, Zakrzewicz A, Berkholz J
The Biochemical journal 2021 Jan 15;478(1):217-234
The Biochemical journal 2021 Jan 15;478(1):217-234
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Duan S, Li H, Zhang Y, Yang S, Chen Y, Qiu B, Huang C, Wang J, Li J, Zhu X, Yan X
The EMBO journal 2021 Jan 15;40(2):e105499
The EMBO journal 2021 Jan 15;40(2):e105499
Structural basis of GABARAP-mediated GABA(A) receptor trafficking and functions on GABAergic synaptic transmission.
Ye J, Zou G, Zhu R, Kong C, Miao C, Zhang M, Li J, Xiong W, Wang C
Nature communications 2021 Jan 12;12(1):297
Nature communications 2021 Jan 12;12(1):297
Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection.
Huang KY, Lin MS, Kuo TC, Chen CL, Lin CC, Chou YC, Chao TL, Pang YH, Kao HC, Huang RS, Lin S, Chang SY, Yang PC
EMBO molecular medicine 2021 Jan 11;13(1):e12828
EMBO molecular medicine 2021 Jan 11;13(1):e12828
Protective effect of thioredoxin reductase 1 in Parkinson's disease.
Liu Z, Ye Q, Wang F, Guo Y, Cui R, Wang J, Wang D
Neuroscience letters 2021 Jan 10;741:135457
Neuroscience letters 2021 Jan 10;741:135457
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Qiu Y, Ren K, Zhao W, Yu Q, Guo R, He J, Mei L, Liu Y, Tang J, Xu S, Li J, Wei J, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Sun Z, Zhang L, Li L, Shao C, Liu J, Zhou M, Wang Z
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
Exosome carrying PSGR promotes stemness and epithelial-mesenchymal transition of low aggressive prostate cancer cells.
Li Y, Li Q, Li D, Gu J, Qian D, Qin X, Chen Y
Life sciences 2021 Jan 1;264:118638
Life sciences 2021 Jan 1;264:118638
Deficiency of NEAT1 prevented MPP(+)-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277-5p/ARHGAP26 axis.
Zhou S, Zhang D, Guo J, Chen Z, Chen Y, Zhang J
Brain research 2021 Jan 1;1750:147156
Brain research 2021 Jan 1;1750:147156
Dietary alpha-lipoic acid supplementation improves spermatogenesis and semen quality via antioxidant and anti-apoptotic effects in aged breeder roosters.
Ye N, Lv Z, Dai H, Huang Z, Shi F
Theriogenology 2021 Jan 1;159:20-27
Theriogenology 2021 Jan 1;159:20-27
Disruption of P2X4 purinoceptor and suppression of the inflammation associated with cerebral aneurysm formation.
Fukuda M, Fukuda S, Ando J, Yamamoto K, Yonemoto N, Suzuki T, Niwa Y, Inoue T, Satoh-Asahara N, Hasegawa K, Shimatsu A, Tsukahara T
Journal of neurosurgery 2021 Jan 1;134(1):102-114
Journal of neurosurgery 2021 Jan 1;134(1):102-114
Tripchlorolide attenuates β-amyloid generation by inducing NEP activity in N2a/APP695 cells.
Zeng Y, Li Y, Shen H, Lin N, Zhang J
Translational neuroscience 2021 Jan 1;12(1):301-308
Translational neuroscience 2021 Jan 1;12(1):301-308
Vitamin D3 reduces hippocampal NR2A and anxiety in nicotine withdrawal mice.
Wu B, Tao X, Liu C, Li H, Jiang T, Chen Z, Wang Q, Liu F, Mu M, Chen Z
Translational neuroscience 2021 Jan 1;12(1):273-281
Translational neuroscience 2021 Jan 1;12(1):273-281
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Gong X, Li T, Wan R, Sha L
International immunopharmacology 2021 Feb;91:107173
International immunopharmacology 2021 Feb;91:107173
Integrative identification of the pathogenic role of a novel G6PD missense mutation c.697G>C.
Zhang H, Peng D, Shu Y, Zhu D, Hu W, Yu C, Zhang J, Liu S, Wan K, Yuan Z, Liu H, Wang D, Jiang T, Yu J, Zhang P, Zou L
Annals of translational medicine 2021 Feb;9(3):194
Annals of translational medicine 2021 Feb;9(3):194
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Jiao Y, Zhao D, Gao F, Hu X, Hu X, Li M, Cui Y, Wei X, Xie C, Zhao Y, Gao Y
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/β-catenin signaling.
Zhao R, Wang S, Liu J, Xu C, Zhang S, Shao Y, Duan X
Journal of bioenergetics and biomembranes 2021 Feb;53(1):85-96
Journal of bioenergetics and biomembranes 2021 Feb;53(1):85-96
Meningioma-associated protein 30 accelerates the proliferation and invasion of hepatocellular carcinoma by modulating Wnt/GSK-3β/β-catenin signaling.
Zhang Y, Li H, Wang J, Geng X, Hai J
Journal of bioenergetics and biomembranes 2021 Feb;53(1):73-83
Journal of bioenergetics and biomembranes 2021 Feb;53(1):73-83
BRCC36 functions noncatalytically to promote antiviral response by maintaining STAT1 protein stability.
Cheng Q, Feng Q, Xu Y, Zuo Y, Liu J, Yuan Y, Miao Y, Liu Y, Lei L, Guo T, Zhang L, Wu D, Zheng H
European journal of immunology 2021 Feb;51(2):296-310
European journal of immunology 2021 Feb;51(2):296-310
DNA methylation determines the regulation of pregnane X receptor on CYP3A4 expression.
Wang X, Wei L, Yang J, Wang Y, Chen S, Yang K, Meng X, Zhang L
Clinical and experimental pharmacology & physiology 2021 Feb;48(2):250-259
Clinical and experimental pharmacology & physiology 2021 Feb;48(2):250-259
Melatonin inhibits RANKL‑induced osteoclastogenesis through the miR‑882/Rev‑erbα axis in Raw264.7 cells.
Tian Y, Gong Z, Zhao R, Zhu Y
International journal of molecular medicine 2021 Feb;47(2):633-642
International journal of molecular medicine 2021 Feb;47(2):633-642
Effect of claudin 1 on cell proliferation, migration and apoptosis in human cervical squamous cell carcinoma.
Shen Z, Song W, Qian L, Zhu J, Li Y, Li M, Zhang T, Zhao W, Zhou Y, Yang X
Oncology reports 2021 Feb;45(2):606-618
Oncology reports 2021 Feb;45(2):606-618
Primary Cutaneous Aspergillosis in a Patient with CARD9 Deficiency and Aspergillus Susceptibility of Card9 Knockout Mice.
Zhang Y, Huang C, Song Y, Ma Y, Wan Z, Zhu X, Wang X, Li R
Journal of clinical immunology 2021 Feb;41(2):427-440
Journal of clinical immunology 2021 Feb;41(2):427-440
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Wo X, Yuan Y, Xu Y, Chen Y, Wang Y, Zhao S, Lin L, Zhong X, Wang Y, Zhong Z, Zhao W
Virologica Sinica 2021 Feb;36(1):95-103
Virologica Sinica 2021 Feb;36(1):95-103
Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible role in preeclampsia.
Sun M, Gao J, Meng T, Liu S, Chen H, Liu Q, Xing X, Zhao C, Luo Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21169
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21169
Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting the activation of cardiac fibroblasts.
Li T, Zhuang Y, Yang W, Xie Y, Shang W, Su S, Dong X, Wu J, Jiang W, Zhou Y, Li Y, Zhou X, Zhang M, Lu Y, Pan Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21162
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21162
RAB31 marks and controls an ESCRT-independent exosome pathway.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, Zhang R, Wu Y, Gao S, Kang T
Cell research 2021 Feb;31(2):157-177
Cell research 2021 Feb;31(2):157-177
Overexpression of thioredoxin reductase 1 can reduce DNA damage, mitochondrial autophagy and endoplasmic reticulum stress in Parkinson's disease.
Liu Z, Ye Q, Wang F, Guo Y, Cui R, Wang J, Wang D
Experimental brain research 2021 Feb;239(2):475-490
Experimental brain research 2021 Feb;239(2):475-490
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Gu M, Zhou X, Sohn JH, Zhu L, Jie Z, Yang JY, Zheng X, Xie X, Yang J, Shi Y, Brightbill HD, Kim JB, Wang J, Cheng X, Sun SC
Nature immunology 2021 Feb;22(2):193-204
Nature immunology 2021 Feb;22(2):193-204
α-ketoglutarate delays age-related fertility decline in mammals.
Zhang Z, He C, Gao Y, Zhang L, Song Y, Zhu T, Zhu K, Lv D, Wang J, Tian X, Ma T, Ji P, Cui W, Liu G
Aging cell 2021 Feb;20(2):e13291
Aging cell 2021 Feb;20(2):e13291
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Wang Y, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J
Biological trace element research 2021 Feb;199(2):703-711
Biological trace element research 2021 Feb;199(2):703-711
Imperatorin ameliorates mast cell-mediated allergic airway inflammation by inhibiting MRGPRX2 and CamKII/ERK signaling pathway.
Wang N, Wang J, Zhang Y, Zeng Y, Hu S, Bai H, Hou Y, Wang C, He H, He L
Biochemical pharmacology 2021 Feb;184:114401
Biochemical pharmacology 2021 Feb;184:114401
Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission.
Li J, Liang L, Jiang L, Wang Q, Wen X, Zhao Y, Cui P, Zhang Y, Wang G, Li Q, Deng G, Shi J, Tian G, Zeng X, Jiang Y, Liu L, Chen H, Li C
PLoS pathogens 2021 Feb;17(2):e1009336
PLoS pathogens 2021 Feb;17(2):e1009336
A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome.
Yoshikawa T, Taniguchi S, Kato H, Iwata-Yoshikawa N, Tani H, Kurosu T, Fujii H, Omura N, Shibamura M, Watanabe S, Egawa K, Inagaki T, Sugimoto S, Phanthanawiboon S, Harada S, Yamada S, Fukushi S, Morikawa S, Nagata N, Shimojima M, Saijo M
PLoS pathogens 2021 Feb;17(2):e1008859
PLoS pathogens 2021 Feb;17(2):e1008859
Enhanced UV-B radiation affects AUR1 regulation of mitotic spindle morphology leading to aberrant mitosis.
Wang J, Yan X, Chen H, Feng J, Han R
Plant physiology and biochemistry : PPB 2021 Feb;159:160-170
Plant physiology and biochemistry : PPB 2021 Feb;159:160-170
G-Rh4 improves pancreatic β-cells dysfunction in vivo and in vitro by increased expression of Nrf2 and its target genes.
Liu Y, Deng J, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111925
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111925
Yishen-tongbi decoction inhibits excessive activation of B cells by activating the FcγRIIb/Lyn/SHP-1 pathway and attenuates the inflammatory response in CIA rats.
Hu C, Peng S, Zhao L, Li M, Liu M, Xu Y, Chen G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111166
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111166
Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.
Liu X, Chu B, Jin S, Li M, Xu Y, Yang H, Feng Z, Bi J, Wang P
The International journal of neuroscience 2021 Feb;131(2):154-162
The International journal of neuroscience 2021 Feb;131(2):154-162
Targeted-delivery of siRNA via a polypeptide-modified liposome for the treatment of gp96 over-expressed breast cancer.
Liang Z, Du L, Zhang E, Zhao Y, Wang W, Ma P, Dai M, Zhao Q, Xu H, Zhang S, Zhen Y
Materials science & engineering. C, Materials for biological applications 2021 Feb;121:111847
Materials science & engineering. C, Materials for biological applications 2021 Feb;121:111847
A newly identified small molecular compound acts as a protein kinase inhibitor to suppress metastasis of colorectal cancer.
Qi L, Zhang Y, Song F, Han Y, Ding Y
Bioorganic chemistry 2021 Feb;107:104625
Bioorganic chemistry 2021 Feb;107:104625
MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1α/PPAR-γ pathway.
Wang W, Xu RL, He P, Chen R
Journal of inflammation (London, England) 2021 Feb 8;18(1):8
Journal of inflammation (London, England) 2021 Feb 8;18(1):8
Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation.
Wang X, Chen L, Xu Y, Wang W, Wang Y, Zhang Z, Zheng J, Bao H
European journal of pharmacology 2021 Feb 5;892:173734
European journal of pharmacology 2021 Feb 5;892:173734
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
Zhou K, Xu Y, Wang Q, Dong L
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Veenstra JP, Vemu B, Tocmo R, Nauman MC, Johnson JJ
Nutrients 2021 Feb 27;13(3)
Nutrients 2021 Feb 27;13(3)
Downregulation of IRAK3 by miR-33b-3p relieves chondrocyte inflammation and apoptosis in an in vitro osteoarthritis model.
Tao T, Zhang Y, Wei H, Heng K
Bioscience, biotechnology, and biochemistry 2021 Feb 24;85(3):545-552
Bioscience, biotechnology, and biochemistry 2021 Feb 24;85(3):545-552
Inhibition of Protein N-Glycosylation Blocks SARS-CoV-2 Infection.
Casas-Sanchez A, Romero-Ramirez A, Hargreaves E, Ellis CC, Grajeda BI, Estevao IL, Patterson EI, Hughes GL, Almeida IC, Zech T, Acosta-Serrano Á
mBio 2021 Feb 22;13(1):e0371821
mBio 2021 Feb 22;13(1):e0371821
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
Li MJ, Xiong D, Huang H, Wen ZY
Biomedical and environmental sciences : BES 2021 Feb 20;34(2):139-151
Biomedical and environmental sciences : BES 2021 Feb 20;34(2):139-151
Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.
Gu X, Liu Y, Wang N, Zhen J, Zhang B, Hou S, Cui Z, Wan Q, Feng H
Free radical biology & medicine 2021 Feb 20;164:329-340
Free radical biology & medicine 2021 Feb 20;164:329-340
SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.
Malnar M, Rogelj B
Journal of cell science 2021 Feb 19;134(4)
Journal of cell science 2021 Feb 19;134(4)
CALM1 promotes progression and dampens chemosensitivity to EGFR inhibitor in esophageal squamous cell carcinoma.
Liu T, Han X, Zheng S, Liu Q, Tuerxun A, Zhang Q, Yang L, Lu X
Cancer cell international 2021 Feb 18;21(1):121
Cancer cell international 2021 Feb 18;21(1):121
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Ni C, Gao S, Zheng Y, Liu P, Zhai Y, Huang W, Jiang H, Lv Q, Kong D, Jiang Y
Infection and immunity 2021 Feb 16;89(3)
Infection and immunity 2021 Feb 16;89(3)
Hippocampal LASP1 ameliorates chronic stress-mediated behavioral responses in a mouse model of unpredictable chronic mild stress.
Cui YH, Fu A, Wang XQ, Tu BX, Chen KZ, Wang YK, Hu QG, Wang LF, Hu ZL, Pan PH, Li F, Bi FF, Li CQ
Neuropharmacology 2021 Feb 15;184:108410
Neuropharmacology 2021 Feb 15;184:108410
Down-regulation of the Sp1 transcription factor by an increase of microRNA-4497 in human placenta is associated with early recurrent miscarriage.
Tang H, Pan L, Xiong Y, Wang L, Cui Y, Liu J, Tang L
Reproductive biology and endocrinology : RB&E 2021 Feb 12;19(1):21
Reproductive biology and endocrinology : RB&E 2021 Feb 12;19(1):21
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Wang R, Peng L, Lv D, Shang F, Yan J, Li G, Li D, Ouyang J, Yang J
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X.
So LY, Miller JE
Behavioural brain research 2021 Feb 1;398:112955
Behavioural brain research 2021 Feb 1;398:112955
Liraglutide preconditioning attenuates myocardial ischemia/ reperfusion injury via homer1 activation.
Cui X, Liang H, Hao C, Jing X
Aging 2021 Feb 1;13(5):6625-6633
Aging 2021 Feb 1;13(5):6625-6633
Dehydroevodiamine ameliorates indomethacin-induced gastric injury via inhibition of ERK and p38 signaling pathway.
Wei Y, Ren S, Wang J, Wang Y, Cui Y, Tian M, Wang R, Liu H, Zhao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153764
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153764
CQMUH-011 mitigates autoimmune hepatitis via inhibiting the function of T lymphocytes.
Ling Q, Hu X, Jiang R, Liu H, Qiu H, Jiang X, Zubreri A, Zhu H, Wan J, Liu Y
Drug development research 2021 Dec;82(8):1111-1123
Drug development research 2021 Dec;82(8):1111-1123
Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway.
Shi W, Men L, Pi X, Jiang T, Peng D, Huo S, Luo P, Wang M, Guo J, Jiang Y, Peng L, Lin L, Li S, Lv J
International journal of oncology 2021 Dec;59(6)
International journal of oncology 2021 Dec;59(6)
Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice.
Cheng L, Wang X, Ma X, Xu H, Yang Y, Zhang D
Pharmaceutical biology 2021 Dec;59(1):557-564
Pharmaceutical biology 2021 Dec;59(1):557-564
Hypouricaemic and nephroprotective effects of Poria cocos in hyperuricemic mice by up-regulating ATP-binding cassette super-family G member 2.
Liang D, Yong T, Diao X, Chen S, Chen D, Xiao C, Zuo D, Xie Y, Zhou X, Hu H
Pharmaceutical biology 2021 Dec;59(1):275-286
Pharmaceutical biology 2021 Dec;59(1):275-286
CircRNA Lrp6 promotes cementoblast differentiation via miR-145a-5p/Zeb2 axis.
Li M, Du M, Wang Y, Zhu J, Pan J, Cao Z, He H
Journal of periodontal research 2021 Dec;56(6):1200-1212
Journal of periodontal research 2021 Dec;56(6):1200-1212
Semaphorin 3A promotes the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells in inflammatory environments by suppressing the Wnt/β-catenin signaling pathway.
Sun Z, Yan K, Liu S, Yu X, Xu J, Liu J, Li S
Journal of molecular histology 2021 Dec;52(6):1245-1255
Journal of molecular histology 2021 Dec;52(6):1245-1255
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.
Du L, Xie Y, Zheng K, Wang N, Gao M, Yu T, Cao L, Shao Q, Zou Y, Xia W, Fang Q, Zhao B, Guo D, Peng X, Pan JA
Redox biology 2021 Dec;48:102199
Redox biology 2021 Dec;48:102199
miR-483-3p Promotes IL-33 Production from Fibroblast-Like Synoviocytes by Regulating ERK Signaling in Rheumatoid Arthritis.
Zhang K, Fu W, Zhao S, Jiao T, Wu D, Wang Y
Inflammation 2021 Dec;44(6):2302-2308
Inflammation 2021 Dec;44(6):2302-2308
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Li TH, Zhao BB, Qin C, Wang YY, Li ZR, Cao HT, Yang XY, Zhou XT, Wang WB
Cellular oncology (Dordrecht, Netherlands) 2021 Dec;44(6):1425-1437
Cellular oncology (Dordrecht, Netherlands) 2021 Dec;44(6):1425-1437
Hypoxia Inhibits Proliferation of Human Dermal Lymphatic Endothelial Cells via Downregulation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 Expression.
Xie Q, Shang TY, Feng S, Zhan RC, Liang J, Fan MG, Zhang L, Liu J
Current medical science 2021 Dec;41(6):1192-1197
Current medical science 2021 Dec;41(6):1192-1197
HDAC9 in the Injury of Vascular Endothelial Cell Mediated by P38 MAPK Pathway.
Kuang X, Chen S, Lao J, Chen Y, Jia D, Tu L, Ma L, Liao X, Zhao W, Li Q
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Dec;41(12):439-449
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Dec;41(12):439-449
Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induces p53-Mediated Apoptosis.
Li P, Jiang H, Peng H, Zeng W, Zhong Y, He M, Xie L, Chen J, Guo D, Wu J, Li CM
Virologica Sinica 2021 Dec;36(6):1411-1420
Virologica Sinica 2021 Dec;36(6):1411-1420
Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms.
Zhu R, Yan T, Feng Y, Liu Y, Cao H, Peng G, Yang Y, Xu Z, Liu J, Hou W, Wang X, Li Z, Deng L, Wang S, Li J, Han Q, Li H, Shan G, Cao Y, An X, Yan J, Zhang Z, Li H, Qu X, Zhu J, Zhou S, Wang J, Zhang F, Gao J, Jin R, Xu D, Ma YQ, Huang T, Peng S, Zheng Z, Stambler I, Gilson E, Lim LW, Moskalev A, Cano A, Chakrabarti S, Ulfhake B, Su H, Xu H, Xu S, Wei F, Brown-Borg HM, Min KJ, Ellison-Hughes G, Caruso C, Jin K, Zhao RC
Cell research 2021 Dec;31(12):1244-1262
Cell research 2021 Dec;31(12):1244-1262
LncRNA HLA-F-AS1 promotes colorectal cancer metastasis by inducing PFN1 in colorectal cancer-derived extracellular vesicles and mediating macrophage polarization.
Zhang J, Li S, Zhang X, Li C, Zhang J, Zhou W
Cancer gene therapy 2021 Dec;28(12):1269-1284
Cancer gene therapy 2021 Dec;28(12):1269-1284
Neferine improves oxidative stress and apoptosis in benign prostate hyperplasia via Nrf2-ARE pathway.
Jahan N, Chowdhury A, Li T, Xu K, Wei F, Wang S
Redox report : communications in free radical research 2021 Dec;26(1):1-9
Redox report : communications in free radical research 2021 Dec;26(1):1-9
Baicalein pre-treatment alleviates hepatic ischemia/reperfusion injury in mice by regulating the Nrf2/ARE pathway.
Zhou Y, Tan Z, Huang H, Zeng Y, Chen S, Wei J, Huang G, Qian C, Yuan G, He S
Experimental and therapeutic medicine 2021 Dec;22(6):1380
Experimental and therapeutic medicine 2021 Dec;22(6):1380
Expression and role of interleukin-1β and associated biomarkers in deep vein thrombosis.
Pai RZ, Fang Q, Tian G, Zhu B, Ge X
Experimental and therapeutic medicine 2021 Dec;22(6):1366
Experimental and therapeutic medicine 2021 Dec;22(6):1366
Knockdown of RREB1 inhibits cell proliferation via enhanced p16 expression in gastric cancer.
Gao Q, Wu Y, Lu C, Kai W, Xie W, Wang Q, Wang L, Liu S, Pan Y
Cell cycle (Georgetown, Tex.) 2021 Dec;20(23):2465-2475
Cell cycle (Georgetown, Tex.) 2021 Dec;20(23):2465-2475
β2-adrenoreceptor agonist ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of mitochondrial biogenesis.
Chen N, Ge MM, Li DY, Wang XM, Liu DQ, Ye DW, Tian YK, Zhou YQ, Chen JP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112331
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112331
Inflammatory arthritis increases the susceptibility to acute immune-mediated hepatitis in mice through enhancing leptin expression in T cells.
Wang Y, Wang P, Xu Q, Dong L, Liu Y, Chen Y, Zhou J, Lu X, Zuo D, Chen Q
Molecular immunology 2021 Dec;140:97-105
Molecular immunology 2021 Dec;140:97-105
A polydopamine-assisted strontium-substituted apatite coating for titanium promotes osteogenesis and angiogenesis via FAK/MAPK and PI3K/AKT signaling pathways.
Sun Y, Li Y, Zhang Y, Wang T, Lin K, Liu J
Materials science & engineering. C, Materials for biological applications 2021 Dec;131:112482
Materials science & engineering. C, Materials for biological applications 2021 Dec;131:112482
Downregulation of Insulin-Like Growth Factor-1 Receptor Mediates Chondrocyte Death and Matrix Degradation in Kashin-Beck Disease.
Zhang M, Wang W, Wang H, Liu Y, Li Z, Yi C, Shi Y, Ma T, Chen J
Cartilage 2021 Dec;13(1_suppl):809S-817S
Cartilage 2021 Dec;13(1_suppl):809S-817S
MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.
Xu W, Ye L, Wu H
Bioengineered 2021 Dec;12(2):9411-9423
Bioengineered 2021 Dec;12(2):9411-9423
Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.
Xu Q, Liu Z, Zhu ZQ, Fan Y, Chen R, Xie XH, Cheng M
Bioengineered 2021 Dec;12(2):12179-12190
Bioengineered 2021 Dec;12(2):12179-12190
Proto-oncogene tyrosine-protein kinase SRC (Src) inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models.
Cai Y, Xu J, Cheng Q
Bioengineered 2021 Dec;12(2):11390-11398
Bioengineered 2021 Dec;12(2):11390-11398
HIG1 domain family member 1A disrupts proliferation, migration, and invasion of colon adenocarcinoma cells.
Xu Z, Sun J, Mao Y, Chen Y, Zhang T, Qin Y, Hua D
Bioengineered 2021 Dec;12(2):10501-10511
Bioengineered 2021 Dec;12(2):10501-10511
MicroRNA-582-5p promotes triple-negative breast cancer invasion and metastasis by antagonizing CMTM8.
Zeng X, Ma X, Guo H, Wei L, Zhang Y, Sun C, Han N, Sun S, Zhang N
Bioengineered 2021 Dec;12(2):10126-10135
Bioengineered 2021 Dec;12(2):10126-10135
MicroRNA-301b-3p facilitates cell proliferation and migration in colorectal cancer by targeting HOXB1.
Xiong J, Zhang L, Tang R, Zhu Z
Bioengineered 2021 Dec;12(1):5839-5849
Bioengineered 2021 Dec;12(1):5839-5849
All-trans-retinoic acid suppresses rat embryo hindlimb bud mesenchymal chondrogenesis by modulating HoxD9 expression.
Hong Q, Li XD, Xie P, Du SX
Bioengineered 2021 Dec;12(1):3900-3911
Bioengineered 2021 Dec;12(1):3900-3911
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, Tan C, Chen H, Wang X
Virulence 2021 Dec;12(1):2296-2313
Virulence 2021 Dec;12(1):2296-2313
Inhibition of micro RNA miR-122-5p prevents lipopolysaccharide-induced myocardial injury by inhibiting oxidative stress, inflammation and apoptosis via targeting GIT1.
Song W, Zhang T, Yang N, Zhang T, Wen R, Liu C
Bioengineered 2021 Dec;12(1):1902-1915
Bioengineered 2021 Dec;12(1):1902-1915
Long non-coding RNA MCM3AP-AS1 protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced inflammation via regulating miR-138-5p/SIRT1.
Shi J, Cao F, Chang Y, Xin C, Jiang X, Xu J, Lu S
Bioengineered 2021 Dec;12(1):1445-1456
Bioengineered 2021 Dec;12(1):1445-1456
Bushen Yijing Decoction (BSYJ) exerts an anti-systemic sclerosis effect via regulating MicroRNA-26a /FLI1 axis.
Cheng Z, Zhang J, Deng W, Lin S, Li D, Zhu K, Qi Q
Bioengineered 2021 Dec;12(1):1212-1225
Bioengineered 2021 Dec;12(1):1212-1225
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Zhang L, Zhu T, He F, Li X
International immunopharmacology 2021 Dec;101(Pt B):108238
International immunopharmacology 2021 Dec;101(Pt B):108238
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Li L, Ji Y, Zhang L, Cai H, Ji Z, Gu L, Yang S
International immunopharmacology 2021 Dec;101(Pt B):108222
International immunopharmacology 2021 Dec;101(Pt B):108222
MicroRNA-30d target TIMP3 induces pituitary tumor cell growth and invasion.
Sun B, Dai C, Zhao S, Dong H, Liu H, Li Y, Wang R, Kang J
Gland surgery 2021 Dec;10(12):3314-3323
Gland surgery 2021 Dec;10(12):3314-3323
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M
International journal of molecular sciences 2021 Dec 9;22(24)
International journal of molecular sciences 2021 Dec 9;22(24)
Screening and Identification of Differential Ovarian Proteins before and after Induced Ovulation via Seminal Plasma in Bactrian Camels.
Wang Q, Zhang Q, Li Y, Zhao X, Zhang Y
Animals : an open access journal from MDPI 2021 Dec 9;11(12)
Animals : an open access journal from MDPI 2021 Dec 9;11(12)
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability.
Ruggiano A, Vaz B, Kilgas S, Popović M, Rodriguez-Berriguete G, Singh AN, Higgins GS, Kiltie AE, Ramadan K
Cell reports 2021 Dec 7;37(10):110080
Cell reports 2021 Dec 7;37(10):110080
Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway.
Zhong T, Feng M, Su M, Wang D, Li Q, Jia S, Luo F, Wang H, Hu E, Yang X, Fan Y
Journal of ethnopharmacology 2021 Dec 5;281:114458
Journal of ethnopharmacology 2021 Dec 5;281:114458
Rapamycin Suppresses Penile NADPH Oxidase Activity to Preserve Erectile Function in Mice Fed a Western Diet.
La Favor JD, Pierre CJ, Bivalacqua TJ, Burnett AL
Biomedicines 2021 Dec 30;10(1)
Biomedicines 2021 Dec 30;10(1)
MicroRNA-7-5p Inhibits Migration, Invasion and Metastasis of Intrahepatic Cholangiocarcinoma by Inhibiting MyD88.
Tang Y, Tang Z, Yang J, Liu T, Tang Y
Journal of clinical and translational hepatology 2021 Dec 28;9(6):809-817
Journal of clinical and translational hepatology 2021 Dec 28;9(6):809-817
Cordycepin augments the chemosensitivity of osteosarcoma to cisplatin by activating AMPK and suppressing the AKT signaling pathway.
Li HB, Chen JK, Su ZX, Jin QL, Deng LW, Huang G, Shen JN
Cancer cell international 2021 Dec 25;21(1):706
Cancer cell international 2021 Dec 25;21(1):706
Host cells with transient overexpression of MDR1 as a novel in vitro model for evaluating on-target effect for activity against the epicellular Cryptosporidium parasite.
Yang B, Wang D, Liu M, Wu X, Yin J, Zhu G
The Journal of antimicrobial chemotherapy 2021 Dec 24;77(1):124-134
The Journal of antimicrobial chemotherapy 2021 Dec 24;77(1):124-134
Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression.
Lv W, Tan Y, Xiong M, Zhao C, Wang Y, Wu M, Wu Y, Zhang Q
Journal of translational medicine 2021 Dec 24;19(1):527
Journal of translational medicine 2021 Dec 24;19(1):527
Identification of the Key Genes Associated with the Yak Hair Follicle Cycle.
Zhang X, Bao P, Ye N, Zhou X, Zhang Y, Liang C, Guo X, Chu M, Pei J, Yan P
Genes 2021 Dec 23;13(1)
Genes 2021 Dec 23;13(1)
Ferroptosis-related gene signature correlates with the tumor immune features and predicts the prognosis of glioma patients.
Hu Y, Tu Z, Lei K, Huang K, Zhu X
Bioscience reports 2021 Dec 22;41(12)
Bioscience reports 2021 Dec 22;41(12)
Anti-Inflammatory Effects and Mechanisms of Pudilan Antiphlogistic Oral Liquid.
Tian G, Gu X, Bao K, Yu X, Zhang Y, Xu Y, Zheng J, Hong M
ACS omega 2021 Dec 21;6(50):34512-34524
ACS omega 2021 Dec 21;6(50):34512-34524
Heparanase-Induced Activation of AKT Stabilizes β-Catenin and Modulates Wnt/β-Catenin Signaling during Herpes Simplex Virus 1 Infection.
Koujah L, Madavaraju K, Agelidis AM, Patil CD, Shukla D
mBio 2021 Dec 21;12(6):e0279221
mBio 2021 Dec 21;12(6):e0279221
A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment.
Chen J, Han S, Chen J, Hu P, Zeng Z, Hu Y, Xiong H, Ke Z, Zhang Y, Xu F, Zhao G
Cancer cell international 2021 Dec 20;21(1):692
Cancer cell international 2021 Dec 20;21(1):692
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Chen J, Mao K, Yu H, Wen Y, She H, Zhang H, Liu L, Li M, Li W, Zou F
Journal of neuroinflammation 2021 Dec 20;18(1):295
Journal of neuroinflammation 2021 Dec 20;18(1):295
Role of clusterin in the regulation of trophoblast development and preeclampsia.
Zeng S, Pan Y, Liu F, Yin J, Jiang M, Long Y, Zhao X, Lash GE, Yang H
Biochemical and biophysical research communications 2021 Dec 17;583:128-134
Biochemical and biophysical research communications 2021 Dec 17;583:128-134
Circular RNA circRAB31 acts as a miR-885-5psponge to suppress gastric cancer progressionvia the PTEN/PI3K/AKT pathway.
Liang X, Qin C, Yu G, Guo X, Cheng A, Zhang H, Wang Z
Molecular therapy oncolytics 2021 Dec 17;23:501-514
Molecular therapy oncolytics 2021 Dec 17;23:501-514
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Feng X, Jiang T, Yang C, Pang S, Ding Z, Hu H, Wang H, Dong L, Yang N
Cell death & disease 2021 Dec 17;13(1):6
Cell death & disease 2021 Dec 17;13(1):6
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
Wang X, Wan W, Lu J, Quan G, Pan X, Liu P
International journal of pharmaceutics 2021 Dec 15;610:121223
International journal of pharmaceutics 2021 Dec 15;610:121223
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT.
Zhang D, Sun L, Zhang J
Toxicology and applied pharmacology 2021 Dec 15;433:115793
Toxicology and applied pharmacology 2021 Dec 15;433:115793
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Gong X, Tian M, Cao N, Yang P, Xu Z, Zheng S, Liao Q, Chen C, Zeng C, Jose PA, Wang DZ, Jian Z, Xiao Y, Jiang DS, Wei X, Zhang B, Wang Y, Chen K, Wu G, Zeng C
The Journal of clinical investigation 2021 Dec 15;131(24)
The Journal of clinical investigation 2021 Dec 15;131(24)
GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.
Guo H, Liu Y, Gu J, Luo J, Ma Y, Xiao F
Biochemical and biophysical research communications 2021 Dec 10;582:8-15
Biochemical and biophysical research communications 2021 Dec 10;582:8-15
RNO3 QTL regulates vascular structure and arterial stiffness in the spontaneously hypertensive rat.
Morgan EE, Morran MP, Horen NG, Weaver DA, Nestor-Kalinoski AL
Physiological genomics 2021 Dec 1;53(12):534-545
Physiological genomics 2021 Dec 1;53(12):534-545
Vps33B in Dendritic Cells Regulates House Dust Mite-Induced Allergic Lung Inflammation.
Ma J, Han M, Yang D, Zheng T, Hu R, Wang B, Ye Y, Liu J, Huang G
Journal of immunology (Baltimore, Md. : 1950) 2021 Dec 1;207(11):2649-2659
Journal of immunology (Baltimore, Md. : 1950) 2021 Dec 1;207(11):2649-2659
BLM helicase inhibition synergizes with PARP inhibition to improve the radiosensitivity of olaparib resistant non-small cell lung cancer cells by inhibiting homologous recombination repair.
Kong Y, Xu C, Sun X, Sun H, Zhao X, He N, Ji K, Wang Q, Du L, Wang J, Zhang M, Liu Y, Wang Y, Liu Q
Cancer biology & medicine 2021 Dec 1;19(8):1150-71
Cancer biology & medicine 2021 Dec 1;19(8):1150-71
Changes in ion channel expression and function associated with cardiac arrhythmogenic remodeling by Sorbs2.
Qian LL, Sun X, Yang J, Wang XL, Ackerman MJ, Wang RX, Xu X, Lee HC, Lu T
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166247
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166247
Peptide DR8 analogs alleviate pulmonary fibrosis via suppressing TGF-β1 mediated epithelial-mesenchymal transition and ERK1/2 pathway in vivo and in vitro.
Wang D, Cheng L, Li J, Deng B, Yan T, Yue X, Zhang J, Zhang B, Xie J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2021 Dec 1;167:106009
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2021 Dec 1;167:106009
Nicaraven inhibits TNFα-induced endothelial activation and inflammation through suppression of NF-κB signaling pathway.
Lin H, Wu X, Yang Y, Wang Z, Huang W, Wang LF, Liu QW, Guan XH, Deng KY, Li TS, Qian Y, Xin HB
Canadian journal of physiology and pharmacology 2021 Aug;99(8):803-811
Canadian journal of physiology and pharmacology 2021 Aug;99(8):803-811
Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.
Wang Z, Feng F, He H, Wu Q, Gu C, Hrovat J, Peng W, Xu Y, Han D, Yang P, Zhou X, Li J, Shan J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Aug;89:153599
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Aug;89:153599
LncRNA AFAP1-AS1 promotes M1 polarization of macrophages and osteogenic differentiation of valve interstitial cells.
He W, Che H, Jin C, Li Y, Li F, Zhou R
Journal of physiology and biochemistry 2021 Aug;77(3):461-468
Journal of physiology and biochemistry 2021 Aug;77(3):461-468
Exosomes derived from mesenchymal stem cells curbs the progression of clear cell renal cell carcinoma through T-cell immune response.
Li D, Lin F, Li G, Zeng F
Cytotechnology 2021 Aug;73(4):593-604
Cytotechnology 2021 Aug;73(4):593-604
Dysregulation of tumour microenvironment driven by circ-TPGS2/miR-7/TRAF6/NF-κB axis facilitates breast cancer cell motility.
Wang S, Feng X, Wang Y, Li Q, Li X
Autoimmunity 2021 Aug;54(5):284-293
Autoimmunity 2021 Aug;54(5):284-293
LPS induces fibroblast-like synoviocytes RSC-364 cells to pyroptosis through NF-κB mediated dual signalling pathway.
Yang P, Feng W, Li C, Kou Y, Li D, Liu S, Hasegawa T, Li M
Journal of molecular histology 2021 Aug;52(4):661-669
Journal of molecular histology 2021 Aug;52(4):661-669
Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.
Trivedi R, Knopf B, Tripathi JK, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
GeroScience 2021 Aug;43(4):1921-1934
GeroScience 2021 Aug;43(4):1921-1934
Suppression of the USP10/CCND1 axis induces glioblastoma cell apoptosis.
Sun T, Xu YJ, Jiang SY, Xu Z, Cao BY, Sethi G, Zeng YY, Kong Y, Mao XL
Acta pharmacologica Sinica 2021 Aug;42(8):1338-1346
Acta pharmacologica Sinica 2021 Aug;42(8):1338-1346
Resveratrol Relieves Hyperoxia-Induced Brain Injury in Neonatal Rats by Activating Sirt1.
Kang L, Dong W, Li X, Ruan Y, Zhang R
American journal of perinatology 2021 Aug;38(S 01):e351-e358
American journal of perinatology 2021 Aug;38(S 01):e351-e358
PLK2 protects retinal ganglion cells from oxidative stress by potentiating Nrf2 signaling via GSK-3β.
Fan Y, Wang J, He N, Feng H
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22815
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22815
Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties.
Pant J, Giovinazzo JA, Tuka LS, Peña D, Raper J, Thomson R
The Journal of biological chemistry 2021 Aug;297(2):100951
The Journal of biological chemistry 2021 Aug;297(2):100951
Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers.
Shi F, Simandi Z, Nagy L, Collins S
The Journal of biological chemistry 2021 Aug;297(2):100941
The Journal of biological chemistry 2021 Aug;297(2):100941
Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF-β/Smad signalling in type 2 diabetic rats.
Tian J, Zhang M, Suo M, Liu D, Wang X, Liu M, Pan J, Jin T, An F
Journal of cellular and molecular medicine 2021 Aug;25(16):7642-7659
Journal of cellular and molecular medicine 2021 Aug;25(16):7642-7659
HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F-actin signalling pathway.
Chen Q, Wang Y, Jiao F, Cao P, Shi C, Pei M, Wang L, Gong Z
Journal of cellular and molecular medicine 2021 Aug;25(15):7218-7228
Journal of cellular and molecular medicine 2021 Aug;25(15):7218-7228
miR‑451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B.
Wu C, Liu X, Li B, Sun G, Peng C, Xiang D
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
Chen M, Huang L, Lv Y, Li L, Dong Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
Weng J, Wang X, Xu B, Li W
Experimental and therapeutic medicine 2021 Aug;22(2):863
Experimental and therapeutic medicine 2021 Aug;22(2):863
Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.
Song CC, Chen GH, Zhong CC, Chen F, Chen SW, Luo Z
Biochimica et biophysica acta. Gene regulatory mechanisms 2021 Aug;1864(8):194723
Biochimica et biophysica acta. Gene regulatory mechanisms 2021 Aug;1864(8):194723
Ponesimod protects against neuronal death by suppressing the activation of A1 astrocytes in early brain injury after experimental subarachnoid hemorrhage.
Zhang L, Guo K, Zhou J, Zhang X, Yin S, Peng J, Liao Y, Jiang Y
Journal of neurochemistry 2021 Aug;158(4):880-897
Journal of neurochemistry 2021 Aug;158(4):880-897
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Bai X, Fu R, Duan Z, Wang P, Zhu C, Fan D
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
Wang Q, Liang D, Shen P, Yu Y, Yan Y, You W
Translational oncology 2021 Aug;14(8):101045
Translational oncology 2021 Aug;14(8):101045
S100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer.
Lin M, Fang Y, Li Z, Li Y, Feng X, Zhan Y, Xie Y, Liu Y, Liu Z, Li G, Shen Z, Deng H
British journal of cancer 2021 Aug;125(5):734-747
British journal of cancer 2021 Aug;125(5):734-747
MSC-Derived Exosomes can Enhance the Angiogenesis of Human Brain MECs and Show Therapeutic Potential in a Mouse Model of Parkinson's Disease.
Xue C, Li X, Ba L, Zhang M, Yang Y, Gao Y, Sun Z, Han Q, Zhao RC
Aging and disease 2021 Aug;12(5):1211-1222
Aging and disease 2021 Aug;12(5):1211-1222
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
Wang HX, Zhang R, Li Z, Wang LS, Yu Y, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
Toxicology research 2021 Aug;10(4):742-750
Toxicology research 2021 Aug;10(4):742-750
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Sun W, Li S, Tang G, Sun S, Luo Y, Bai R, Han L, Jiang X, Gao Y, Huang Z, Zhang J, Gong Y, Xie C
Cancer medicine 2021 Aug;10(15):5256-5269
Cancer medicine 2021 Aug;10(15):5256-5269
Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression.
Yao C, Zhou Y, Wang H, Deng F, Chen Y, Zhu X, Kong Y, Pan L, Xue L, Zhou X, Shi C, Sheng X
Stem cell research & therapy 2021 Aug 9;12(1):447
Stem cell research & therapy 2021 Aug 9;12(1):447
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
Chen X, Zhang W, Xu X
World journal of surgical oncology 2021 Aug 6;19(1):232
World journal of surgical oncology 2021 Aug 6;19(1):232
Compound 968 reverses adriamycin resistance in breast cancer MCF-7(ADR) cells via inhibiting P-glycoprotein function independently of glutaminase.
Yang R, Guo Z, Zhao Y, Ma L, Li B, Yang C
Cell death discovery 2021 Aug 5;7(1):204
Cell death discovery 2021 Aug 5;7(1):204
Novel Metabolic Regulation of Bile Acid Responses to Low Cholesterol in Whole-Grain-Diet-Fed Mice.
Liu J, Wang Y, Xue L, Nie C, Sun J, Fan M, Qian H, Wang L, Li Y
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8440-8447
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8440-8447
The Role of Cell Proliferation and Extracellular Matrix Accumulation Induced by Food Additive Butylated Hydroxytoluene in Uterine Leiomyoma.
Chiang YF, Chen HY, Ali M, Shieh TM, Huang YJ, Wang KL, Chang HY, Huang TC, Hong YH, Hsia SM
Nutrients 2021 Aug 31;13(9)
Nutrients 2021 Aug 31;13(9)
Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor.
Liu J, Bodnar BH, Meng F, Khan AI, Wang X, Saribas S, Wang T, Lohani SC, Wang P, Wei Z, Luo J, Zhou L, Wu J, Luo G, Li Q, Hu W, Ho W
Cell & bioscience 2021 Aug 30;11(1):168
Cell & bioscience 2021 Aug 30;11(1):168
OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human.
Huang X, Park KM, Gontarz P, Zhang B, Pan J, McKenzie Z, Fischer LA, Dong C, Dietmann S, Xing X, Shliaha PV, Yang J, Li D, Ding J, Lungjangwa T, Mitalipova M, Khan SA, Imsoonthornruksa S, Jensen N, Wang T, Kadoch C, Jaenisch R, Wang J, Theunissen TW
Nature communications 2021 Aug 26;12(1):5123
Nature communications 2021 Aug 26;12(1):5123
Elevation of CSF Sortilin Following Subarachnoid Hemorrhage in Patients and Experimental Model Rats.
Wang Y, Wang J, Zuo YC, Jiang J, Tu T, Yan XX, Liu F
Neuroscience 2021 Aug 21;470:23-36
Neuroscience 2021 Aug 21;470:23-36
Protective autophagy attenuates soft substrate-induced apoptosis through ROS/JNK signaling pathway in breast cancer cells.
Chen Y, Li P, Peng Y, Xie X, Zhang Y, Jiang Y, Li T, Qin X, Li S, Yang H, Wu C, Zheng C, Zhu J, You F, Liu Y
Free radical biology & medicine 2021 Aug 20;172:590-603
Free radical biology & medicine 2021 Aug 20;172:590-603
Inhibition of the Ras/ERK1/2 pathway contributes to the protective effect of ginsenoside Re against intimal hyperplasia.
Gao C, Zhang K, Liang F, Ma W, Jiang X, Wang H, Zhan H, Sonkoly E, Hu H, Zhao Z
Food & function 2021 Aug 2;12(15):6755-6765
Food & function 2021 Aug 2;12(15):6755-6765
N(7)-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression.
Dai Z, Liu H, Liao J, Huang C, Ren X, Zhu W, Zhu S, Peng B, Li S, Lai J, Liang L, Xu L, Peng S, Lin S, Kuang M
Molecular cell 2021 Aug 19;81(16):3339-3355.e8
Molecular cell 2021 Aug 19;81(16):3339-3355.e8
Age and gender differences in ACE2 and TMPRSS2 expressions in oral epithelial cells.
Peng J, Sun J, Zhao J, Deng X, Guo F, Chen L
Journal of translational medicine 2021 Aug 19;19(1):358
Journal of translational medicine 2021 Aug 19;19(1):358
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Xia Y, Zhang G, Kou L, Yin S, Han C, Hu J, Wan F, Sun Y, Wu J, Li Y, Huang J, Xiong N, Zhang Z, Wang T
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
LncRNA KCNQ1OT1 activated by c-Myc promotes cell proliferation via interacting with FUS to stabilize MAP3K1 in acute promyelocytic leukemia.
Tang D, Luo Y, Jiang Y, Hu P, Peng H, Wu S, Zhang G, Wang Y
Cell death & disease 2021 Aug 17;12(9):795
Cell death & disease 2021 Aug 17;12(9):795
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Zuo S, Wang B, Liu J, Kong D, Cui H, Jia Y, Wang C, Xu X, Chen G, Wang Y, Yang L, Zhang K, Ai D, Du J, Shen Y, Yu Y
The EMBO journal 2021 Aug 16;40(16):e107403
The EMBO journal 2021 Aug 16;40(16):e107403
Phase separation of Epstein-Barr virus EBNA2 protein reorganizes chromatin topology for epigenetic regulation.
Yang Y, Ye X, Dai R, Li Z, Zhang Y, Xue W, Zhu Y, Feng D, Qin L, Wang X, Lei B, Liao S, Hao B
Communications biology 2021 Aug 16;4(1):967
Communications biology 2021 Aug 16;4(1):967
MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies.
Li Y, Fan C, Wang L, Lan T, Gao R, Wang W, Yu SY
The Journal of clinical investigation 2021 Aug 16;131(16)
The Journal of clinical investigation 2021 Aug 16;131(16)
Short-term standard alcohol consumption enhances platelet response to clopidogrel through inhibition of Nrf2/Ces1 pathway and induction of Cyp2c in mice.
Ge PX, Jiang LP, Tai T, Zhu T, Ji JZ, Li YF, Mi QY, Xie HG
Life sciences 2021 Aug 15;279:119268
Life sciences 2021 Aug 15;279:119268
Hippocampal miR-211-5p regulates neurogenesis and depression-like behaviors in the rat.
Li Y, Fan C, Gao R, Lan T, Wang W, Yu SY
Neuropharmacology 2021 Aug 15;194:108618
Neuropharmacology 2021 Aug 15;194:108618
Methyltransferase like 13 mediates the translation of Snail in head and neck squamous cell carcinoma.
Wang X, Li K, Wan Y, Chen F, Cheng M, Xiong G, Wang G, Chen S, Chen Z, Chen J, Xu X, Wang C, Peng L, Chen D
International journal of oral science 2021 Aug 11;13(1):26
International journal of oral science 2021 Aug 11;13(1):26
[6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling.
Jiang X, Wang J, Chen P, He Z, Xu J, Chen Y, Liu X, Jiang J
Cancer cell international 2021 Aug 10;21(1):420
Cancer cell international 2021 Aug 10;21(1):420
LncRNA-HAGLR motivates triple negative breast cancer progression by regulation of WNT2 via sponging miR-335-3p.
Jin L, Luo C, Wu X, Li M, Wu S, Feng Y
Aging 2021 Aug 10;13(15):19306-19316
Aging 2021 Aug 10;13(15):19306-19316
Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin.
Hu S, Pi Q, Luo M, Cheng Z, Liang X, Luo S, Xia Y
International immunopharmacology 2021 Apr;93:107388
International immunopharmacology 2021 Apr;93:107388
Comparison of proteomic profiles from the testicular tissue of males with impaired and normal spermatogenesis.
Liang J, Zheng Y, Zeng W, Chen L, Yang S, Du P, Wang Y, Yu X, Zhang X
Systems biology in reproductive medicine 2021 Apr;67(2):127-136
Systems biology in reproductive medicine 2021 Apr;67(2):127-136
Betaine prevented high-fat diet-induced NAFLD by regulating the FGF10/AMPK signaling pathway in ApoE(-/-) mice.
Chen W, Zhang X, Xu M, Jiang L, Zhou M, Liu W, Chen Z, Wang Y, Zou Q, Wang L
European journal of nutrition 2021 Apr;60(3):1655-1668
European journal of nutrition 2021 Apr;60(3):1655-1668
MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche.
Wu N, Sun H, Zhao X, Zhang Y, Tan J, Qi Y, Wang Q, Ng M, Liu Z, He L, Niu X, Chen L, Liu Z, Li HB, Zeng YA, Roulis M, Liu D, Cheng J, Zhou B, Ng LG, Zou D, Ye Y, Flavell RA, Ginhoux F, Su B
Nature 2021 Apr;592(7855):606-610
Nature 2021 Apr;592(7855):606-610
Simvastatin Enhances Muscle Regeneration Through Autophagic Defect-Mediated Inflammation and mTOR Activation in G93ASOD1 Mice.
Wang Y, Bai L, Li S, Wen Y, Liu Q, Li R, Liu Y
Molecular neurobiology 2021 Apr;58(4):1593-1606
Molecular neurobiology 2021 Apr;58(4):1593-1606
A novel model of constrictive pericarditis associated with myocardial fibrosis in rats.
Qiao W, Xiao YJ, Wang X, Sun LJ, Chen YX, Ren WD
Clinical and experimental pharmacology & physiology 2021 Apr;48(4):563-574
Clinical and experimental pharmacology & physiology 2021 Apr;48(4):563-574
Quercetin reverses TNF‑α induced osteogenic damage to human periodontal ligament stem cells by suppressing the NF‑κB/NLRP3 inflammasome pathway.
Zhang W, Jia L, Zhao B, Xiong Y, Wang YN, Liang J, Xu X
International journal of molecular medicine 2021 Apr;47(4)
International journal of molecular medicine 2021 Apr;47(4)
PCSK9 mediates the oxidative low‑density lipoprotein‑induced pyroptosis of vascular endothelial cells via the UQCRC1/ROS pathway.
Zeng J, Tao J, Xi L, Wang Z, Liu L
International journal of molecular medicine 2021 Apr;47(4)
International journal of molecular medicine 2021 Apr;47(4)
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
Ni M, Li J, Zhao H, Xu F, Cheng J, Yu M, Ke G, Wu X
Oncogene 2021 Apr;40(15):2711-2724
Oncogene 2021 Apr;40(15):2711-2724
Inhibition of PAI-1 Promotes Lipolysis and Enhances Weight Loss in Obese Mice.
Levine JA, Olivares S, Miyata T, Vaughan DE, Henkel AS
Obesity (Silver Spring, Md.) 2021 Apr;29(4):713-720
Obesity (Silver Spring, Md.) 2021 Apr;29(4):713-720
Estrogen Regulates Endoplasmic Reticulum Stress-Mediated Apoptosis by ERK-p65 Pathway to Promote Endometrial Angiogenesis.
Zhang Y, Cao C, Du S, Fan L, Zhang D, Wang X, He M
Reproductive sciences (Thousand Oaks, Calif.) 2021 Apr;28(4):1216-1226
Reproductive sciences (Thousand Oaks, Calif.) 2021 Apr;28(4):1216-1226
Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model.
Lin JQ, Tian H, Zhao XG, Lin S, Li DY, Liu YY, Xu C, Mei XF
CNS neuroscience & therapeutics 2021 Apr;27(4):413-425
CNS neuroscience & therapeutics 2021 Apr;27(4):413-425
FGF19 protects skeletal muscle against obesity-induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT-1/PGC-α pathway.
Guo A, Li K, Tian HC, Fan Z, Chen QN, Yang YF, Yu J, Wu YX, Xiao Q
Journal of cellular and molecular medicine 2021 Apr;25(7):3585-3600
Journal of cellular and molecular medicine 2021 Apr;25(7):3585-3600
Long noncoding RNA H19 act as a competing endogenous RNA of Let-7g to facilitate IEC-6 cell migration and proliferation via regulating EGF.
Li C, Li Y, Zhuang M, Zhu B, Zhang W, Yan H, Zhang P, Li D, Yang J, Sun Y, Cui Q, Chen H, Jin P, Xia Z, Sun Y
Journal of cellular physiology 2021 Apr;236(4):2881-2892
Journal of cellular physiology 2021 Apr;236(4):2881-2892
MicroRNA‑592 promotes cell proliferation, migration and invasion in colorectal cancer by directly targeting SPARC.
Pan Z, Xie R, Song W, Gao C
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway.
Shi G, Zhang Z
Oncology letters 2021 Apr;21(4):314
Oncology letters 2021 Apr;21(4):314
Triptolide inhibits human telomerase reverse transcriptase by downregulating translation factors SP1 and c-Myc in Epstein-Barr virus-positive B lymphocytes.
Long C, Xu QB, Ding L, Yang L, Ji W, Gao F, Ji Y
Oncology letters 2021 Apr;21(4):280
Oncology letters 2021 Apr;21(4):280
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Ma C, Feng K, Yang X, Yang Z, Wang Z, Shang Y, Fan G, Liu L, Yang S, Li X, Han J, Duan Y, Chen Y
British journal of pharmacology 2021 Apr;178(7):1620-1638
British journal of pharmacology 2021 Apr;178(7):1620-1638
Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect.
Zhu D, Li S, Chen C, Wang S, Zhu J, Kong L, Luo J
Pharmacological research 2021 Apr;166:105523
Pharmacological research 2021 Apr;166:105523
DDB1- and CUL4-associated factor 8 plays a critical role in spermatogenesis.
Zhang X, Xia Z, Lv X, Li D, Liu M, Zhang R, Ji T, Liu P, Ren R
Frontiers of medicine 2021 Apr;15(2):302-312
Frontiers of medicine 2021 Apr;15(2):302-312
Syntaxin 3 interacts with serotonin transporter and regulates its function.
Motoike S, Taguchi K, Harada K, Asano M, Hide I, Tanaka S, Irifune M, Sakai N
Journal of pharmacological sciences 2021 Apr;145(4):297-307
Journal of pharmacological sciences 2021 Apr;145(4):297-307
Effects of blood oxygen saturation on pulmonary artery remodeling in an in vitro perfusion circuit model.
Liu Y, Wen B, Zhang F, Pan XB
Journal of thoracic disease 2021 Apr;13(4):2169-2176
Journal of thoracic disease 2021 Apr;13(4):2169-2176
EGFR/PPARδ/HSP90 pathway mediates cancer cell metabolism and chemoresistance.
Gou Q, Zhang W, Xu Y, Jin J, Liu Q, Hou Y, Shi J
Journal of cellular biochemistry 2021 Apr;122(3-4):394-402
Journal of cellular biochemistry 2021 Apr;122(3-4):394-402
Long non-coding RNA NEAT1 functions as a competing endogenous RNA to regulate S100A9 expression by sponging miR-196a-5p in rosacea.
Wang L, Wang YJ, Hao D, Wang XY, Li XX, Zhao Q, Li YM, He G, Jiang X
Journal of dermatological science 2021 Apr;102(1):58-67
Journal of dermatological science 2021 Apr;102(1):58-67
Integrative analysis regarding the correlation between GAS2 family genes and human glioma prognosis.
Zhao C, Zhang N, Cui X, Zhang X, Ren Y, Su C, He J, Zhang W, Sun X, Yang J, Gao X
Cancer medicine 2021 Apr;10(8):2826-2839
Cancer medicine 2021 Apr;10(8):2826-2839
Upregulation of LINC00511 expression by DNA hypomethylation promotes the progression of breast cancer.
Liu C, Xu Y, Liu X, Fu Y, Zhu K, Niu Z, Liu J, Qian C
Gland surgery 2021 Apr;10(4):1418-1430
Gland surgery 2021 Apr;10(4):1418-1430
The miR-146b-5p promotes Ewing's sarcoma cells progression via suppressing the expression of BTG2.
Qu L, Zhang W, Li J, Liu P
Science progress 2021 Apr-Jun;104(2):368504211002043
Science progress 2021 Apr-Jun;104(2):368504211002043
Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival.
Agelidis A, Turturice BA, Suryawanshi RK, Yadavalli T, Jaishankar D, Ames J, Hopkins J, Koujah L, Patil CD, Hadigal SR, Kyzar EJ, Campeau A, Wozniak JM, Gonzalez DJ, Vlodavsky I, Li JP, Perkins DL, Finn PW, Shukla D
JCI insight 2021 Apr 8;6(7)
JCI insight 2021 Apr 8;6(7)
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Zhu Y, Wang C, Luo J, Hua S, Li D, Peng L, Liu H, Song L
Food & function 2021 Apr 7;12(7):3120-3131
Food & function 2021 Apr 7;12(7):3120-3131
Iguratimod promotes transformation of mononuclear macrophages in elderly patients with rheumatoid arthritis by nuclear factor-κB pathway.
Liu S, Song LP, Li RB, Feng LH, Zhu H
World journal of clinical cases 2021 Apr 6;9(10):2181-2191
World journal of clinical cases 2021 Apr 6;9(10):2181-2191
Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation.
Huang Y, Sun X, Juan Z, Zhang R, Wang R, Meng S, Zhou J, Li Y, Xu K, Xie K
BMC anesthesiology 2021 Apr 6;21(1):104
BMC anesthesiology 2021 Apr 6;21(1):104
Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.
Li Q, Luan Q, Zhu H, Zhao Y, Ji J, Wu F, Yan J
Biochemical and biophysical research communications 2021 Apr 30;551:78-85
Biochemical and biophysical research communications 2021 Apr 30;551:78-85
Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice.
Sato S, Noda S, Torii S, Amo T, Ikeda A, Funayama M, Yamaguchi J, Fukuda T, Kondo H, Tada N, Arakawa S, Watanabe M, Uchiyama Y, Shimizu S, Hattori N
Human molecular genetics 2021 Apr 30;30(6):443-453
Human molecular genetics 2021 Apr 30;30(6):443-453
IP(6)-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion.
Lin H, Yan Y, Luo Y, So WY, Wei X, Zhang X, Yang X, Zhang J, Su Y, Yang X, Zhang B, Zhang K, Jiang N, Chow BKC, Han W, Wang F, Rao F
Nature communications 2021 Apr 28;12(1):2461
Nature communications 2021 Apr 28;12(1):2461
C/EBPα is indispensable for PML/RARα-mediated suppression of long non-coding RNA NEAT1 in acute promyelocytic leukemia cells.
Tang D, Hu P, Zhu D, Luo Y, Chen M, Zhang G, Wang Y
Aging 2021 Apr 26;13(9):13179-13194
Aging 2021 Apr 26;13(9):13179-13194
An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy.
Xiao Y, Liu Y, Lai Z, Huang J, Li C, Zhang Y, Gong X, Deng J, Ye X, Li X
Journal of ethnopharmacology 2021 Apr 24;270:113806
Journal of ethnopharmacology 2021 Apr 24;270:113806
hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.
Akinyemi AR, Li D, Zhang J, Liu Q
Neuroscience letters 2021 Apr 23;751:135824
Neuroscience letters 2021 Apr 23;751:135824
Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling.
Rogan MR, Patterson LL, Byerly CD, Luo T, Paessler S, Veljkovic V, Quade B, McBride JW
mSphere 2021 Apr 21;6(2)
mSphere 2021 Apr 21;6(2)
Allicin attenuates myocardial apoptosis, inflammation and mitochondrial injury during hypoxia-reoxygenation: an in vitro study.
Deng X, Yang P, Gao T, Liu M, Li X
BMC cardiovascular disorders 2021 Apr 21;21(1):200
BMC cardiovascular disorders 2021 Apr 21;21(1):200
CSF-CN contributes to cancer-induced bone pain via the MKP-1-mediated MAPK pathway.
Chen P, Pan M, Lin QS, Lin XZ, Lin Z
Biochemical and biophysical research communications 2021 Apr 2;547:36-43
Biochemical and biophysical research communications 2021 Apr 2;547:36-43
Anti-spastic effect induced by waggle needling correlates with KCC2-GABA(A) pathway in post-stroke spasticity rats.
Wang JX, Ma LX, Mu JD, Sun TY, Qian X, Yu WY, Tian Y, Zhang Z
Neuroscience letters 2021 Apr 17;750:135810
Neuroscience letters 2021 Apr 17;750:135810
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
Wang Q, Dong Z, Su J, Huang J, Xiao P, Tian L, Chen Y, Ma L, Chen X
Biochemical and biophysical research communications 2021 Apr 16;549:1-7
Biochemical and biophysical research communications 2021 Apr 16;549:1-7
Liver kinase B1 attenuates liver ischemia/reperfusion injury via inhibiting the NLRP3 inflammasome.
Dai J, Chen Q, Huang W, Shi K, Zhang Y, Li T, Mou T, Huang Z, Wu Z
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):601-611
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):601-611
Amplification and expression of c-MET correlate with poor prognosis of patients with gastric cancer and upregulate the expression of PDL1.
Yang Y, Wang C, Dai C, Liu X, Li W, Huang M, Zhao X, Ji D, Li J, Guo W
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):547-557
Acta biochimica et biophysica Sinica 2021 Apr 15;53(5):547-557
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Quan X, Song L, Zheng X, Liu S, Ding H, Li S, Xu G, Li X, Liu L
Neuroscience 2021 Apr 15;460:107-119
Neuroscience 2021 Apr 15;460:107-119
N(6) -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
Lee J, Wu Y, Harada BT, Li Y, Zhao J, He C, Ma Y, Wu X
The EMBO journal 2021 Apr 15;40(8):e106276
The EMBO journal 2021 Apr 15;40(8):e106276
Everolimus regulates the activity of gemcitabine-resistant pancreatic cancer cells by targeting the Warburg effect via PI3K/AKT/mTOR signaling.
Cui J, Guo Y, Wu H, Xiong J, Peng T
Molecular medicine (Cambridge, Mass.) 2021 Apr 13;27(1):38
Molecular medicine (Cambridge, Mass.) 2021 Apr 13;27(1):38
[Sitagliptin inhibits lipopolysaccharide-induced inflammatory response in human gingival fibroblasts by blocking nuclear factor-κB signaling pathway].
Liu X, Kang WY, Shang LL, Ge SH
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 2021 Apr 1;39(2):153-163
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 2021 Apr 1;39(2):153-163
The neuroprotective effect of oxytocin on vincristine-induced neurotoxicity in mice.
Zhu J, Li Y, Liang J, Li J, Huang K, Li J, Liu C
Toxicology letters 2021 Apr 1;340:67-76
Toxicology letters 2021 Apr 1;340:67-76
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs.
Sun L, Li P, Ju X, Rao J, Huang W, Ren L, Zhang S, Xiong T, Xu K, Zhou X, Gong M, Miska E, Ding Q, Wang J, Zhang QC
Cell 2021 Apr 1;184(7):1865-1883.e20
Cell 2021 Apr 1;184(7):1865-1883.e20
MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.
Wang X, Wen Y, Zhang J, Swanson G, Guo S, Cao C, Krawetz SA, Zhang Z, Yuan S
Development (Cambridge, England) 2021 Apr 1;148(7)
Development (Cambridge, England) 2021 Apr 1;148(7)
Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts.
Zhang Q, Mesner LD, Calabrese GM, Dirckx N, Li Z, Verardo A, Yang Q, Tower RJ, Faugere MC, Farber CR, Clemens TL
The Journal of clinical investigation 2021 Apr 1;131(7)
The Journal of clinical investigation 2021 Apr 1;131(7)
Inhibition of excessive mitophagy by N-acetyl-L-tryptophan confers hepatoprotection against Ischemia-Reperfusion injury in rats.
Li H, Pan Y, Wu H, Yu S, Wang J, Zheng J, Wang C, Li J, Jiang J
PeerJ 2020;8:e8665
PeerJ 2020;8:e8665
Hyaluronic acid ameliorates the proliferative ability of human amniotic epithelial cells through activation of TGF-β/BMP signaling.
Tian YB, Wang NX, Xu Y, Yu CY, Liu RM, Luo Y, Xiao JH
PeerJ 2020;8:e10104
PeerJ 2020;8:e10104
Development and Characterisation of an in vitro Model of Wallerian Degeneration.
Elsayed H, Faroni A, Ashraf MR, Osuji J, Wunderley L, Zhang L, Elsobky H, Mansour M, Zidan AS, Reid AJ
Frontiers in bioengineering and biotechnology 2020;8:784
Frontiers in bioengineering and biotechnology 2020;8:784
Olfactomedin-3 Enhances Seizure Activity by Interacting With AMPA Receptors in Epilepsy Models.
Tang S, Wang T, Zhang X, Guo Y, Xu P, Zeng J, Luo Z, Li D, Zheng Y, Luo Y, Yu C, Xu Z
Frontiers in cell and developmental biology 2020;8:722
Frontiers in cell and developmental biology 2020;8:722
Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis.
Yan J, Wang WB, Fan YJ, Bao H, Li N, Yao QP, Huo YL, Jiang ZL, Qi YX, Han Y
Frontiers in cell and developmental biology 2020;8:606989
Frontiers in cell and developmental biology 2020;8:606989
miR-129-5p Inhibits Bone Formation Through TCF4.
Yin C, Tian Y, Yu Y, Yang C, Su P, Zhao Y, Wang X, Zhang K, Pei J, Li D, Chen Z, Zhang Y, Miao Z, Qian A
Frontiers in cell and developmental biology 2020;8:600641
Frontiers in cell and developmental biology 2020;8:600641
MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.
Wang X, Ma Y, Yang LY, Zhao D
Frontiers in cell and developmental biology 2020;8:596329
Frontiers in cell and developmental biology 2020;8:596329
A Novel Signature Constructed by RNA-Binding Protein Coding Genes to Improve Overall Survival Prediction of Glioma Patients.
Tu Z, Shu L, Li J, Wu L, Tao C, Ye M, Zhu X, Huang K
Frontiers in cell and developmental biology 2020;8:588368
Frontiers in cell and developmental biology 2020;8:588368
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
Zhang W, Hou W, Chen M, Chen E, Xue D, Ye C, Li W, Pan Z
Frontiers in cell and developmental biology 2020;8:576104
Frontiers in cell and developmental biology 2020;8:576104
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
Lu Y, Hou K, Li M, Wu X, Yuan S
Frontiers in cell and developmental biology 2020;8:571297
Frontiers in cell and developmental biology 2020;8:571297
An Aurora Kinase B-Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes.
Fu W, Liao Q, Li L, Shi Y, Zeng A, Zeng C, Wang WE
Frontiers in cell and developmental biology 2020;8:570252
Frontiers in cell and developmental biology 2020;8:570252
Overexpression of Toll-Like Receptor 4 Affects Autophagy, Oxidative Stress, and Inflammatory Responses in Monocytes of Transgenic Sheep.
Wang S, Song X, Zhang K, Deng S, Jiao P, Qi M, Lian Z, Yao Y
Frontiers in cell and developmental biology 2020;8:248
Frontiers in cell and developmental biology 2020;8:248
Changes of Gut Microbiota and Its Correlation With Short Chain Fatty Acids and Bioamine in Piglets at the Early Growth Stage.
Qi R, Qiu X, Du L, Wang J, Wang Q, Huang J, Liu Z
Frontiers in veterinary science 2020;7:617259
Frontiers in veterinary science 2020;7:617259
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer.
Zeng Y, Zou M, Liu Y, Que K, Wang Y, Liu C, Gong J, You Y
Frontiers in medicine 2020;7:572494
Frontiers in medicine 2020;7:572494
miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis.
Yang B, Li S, Zhu J, Huang S, Zhang A, Jia Z, Ding G, Zhang Y
Frontiers in medicine 2020;7:411
Frontiers in medicine 2020;7:411
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
Majid A, Wang J, Nawaz M, Abdul S, Ayesha M, Guo C, Liu Q, Liu S, Sun MZ
Frontiers in molecular biosciences 2020;7:223
Frontiers in molecular biosciences 2020;7:223
LncRNA GAS5 promotes apoptosis as a competing endogenous RNA for miR-21 via thrombospondin 1 in ischemic AKI.
Geng X, Song N, Zhao S, Xu J, Liu Y, Fang Y, Liang M, Xu X, Ding X
Cell death discovery 2020;6:19
Cell death discovery 2020;6:19
SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model.
Li R, He M, Wu B, Zhang P, Zhang Q, Chen Y
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(4):e9175
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(4):e9175
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
Huang Y, Liao Y, Zhang H, Li S
The Journal of toxicological sciences 2020;45(9):559-567
The Journal of toxicological sciences 2020;45(9):559-567
In-utero cold stress causes elevation of blood pressure via impaired vascular dopamine D(1) receptor in offspring.
Sun D, Chen K, Wang J, Zhou L, Zeng C
Clinical and experimental hypertension (New York, N.Y. : 1993) 2020;42(2):99-104
Clinical and experimental hypertension (New York, N.Y. : 1993) 2020;42(2):99-104
Deletion of Bmal1 Impairs Pancreatic β-Cell Function via Mitochondrial Signaling Pathway.
Ye L, Wu H, Xu W
BioMed research international 2020;2020:9803024
BioMed research international 2020;2020:9803024
Caulis Sargentodoxae Prescription Plays a Therapeutic Role with Decreased Inflammatory Cytokines in Peritoneal Fluid in the Rat Endometriosis Model.
Zhuang M, Cao Y, Shi Y, Yu L, Niu Y, Zhang T, Sun Z
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9627907
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9627907
Effect of Lentivirus-Mediated miR-499a-3p on Human Umbilical Vein Endothelial Cells.
Zheng H, Li J, Chen Y, Gong D, Wen J, Mai L, Zeng Z
BioMed research international 2020;2020:9372961
BioMed research international 2020;2020:9372961
Bushen Tiaojing (II and III) Decoctions Activate MAPK14 and MAPK3/1 to Promote the Expression of Cumulus Expansion-Related Factors in Mice.
Liang X, Tong X, Du HL, He M, Zhang Y, Duan YC
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9283917
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9283917
Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress.
Xu K, Chai B, Zhang K, Xiong J, Zhu Y, Xu J, An N, Xia W, Ji H, Wu Y, Li H, Xiao J, Feng Z, Zhang H
Oxidative medicine and cellular longevity 2020;2020:8586314
Oxidative medicine and cellular longevity 2020;2020:8586314
PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats.
Li J, Zhang K, Zhang Q, Zhou X, Wen L, Ma J, Niu L, Li C
BioMed research international 2020;2020:8163789
BioMed research international 2020;2020:8163789
Gender Difference on the Effect of Omega-3 Polyunsaturated Fatty Acids on Acetaminophen-Induced Acute Liver Failure.
Liu Y, Chen Y, Xie X, Yin A, Yin Y, Liu Y, Dong L, Zhu Z, Zhou J, Zeng Q, Lu X, Chen Z, Wen K, Zuo D
Oxidative medicine and cellular longevity 2020;2020:8096847
Oxidative medicine and cellular longevity 2020;2020:8096847
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Zhang J, Zhang H, Shi H, Wang F, Du J, Wang Y, Wei Y, Xue W, Li D, Feng Y, Yan J, Gao Y, Li J, Han J
BioMed research international 2020;2020:7838924
BioMed research international 2020;2020:7838924
Neuroprotective Effect of the Inhibitor Salubrinal after Cardiac Arrest in a Rodent Model.
Zhang J, Wang Y, Ju M, Song J, Zheng Y, Lin S, Zhu D, Wen L, Zhong M, Pan S, Yang G
Oxidative medicine and cellular longevity 2020;2020:7468738
Oxidative medicine and cellular longevity 2020;2020:7468738
Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model.
Yang K, Fan B, Zhao Q, Ji Y, Liu P, Gao S, Ren T, Dou Y, Pei M, Yang H
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7291075
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7291075
Cordyceps cicadae Prevents Renal Tubular Epithelial Cell Apoptosis by Regulating the SIRT1/p53 Pathway in Hypertensive Renal Injury.
Huang YS, Wang X, Feng Z, Cui H, Zhu Z, Xia C, Han X, Liu WJ, Liu YN
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7202519
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7202519
Shen Shuai II Recipe Attenuates Apoptosis in 5/6 Renal Ablation/Infarction Rats by Inhibiting p53 and the Mitochondrial Pathway of Apoptosis.
Wang M, Yang J, Wang C
Oxidative medicine and cellular longevity 2020;2020:7083575
Oxidative medicine and cellular longevity 2020;2020:7083575
A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats.
Zhou X, Lu W, Wang Y, Li J, Luo Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6980398
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6980398
Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model.
Liang Q, Lin Q, Li Y, Luo W, Huang X, Jiang Y, Qin C, Nong J, Chen X, Sooranna SR, Pinhu L
Journal of immunology research 2020;2020:6644687
Journal of immunology research 2020;2020:6644687
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT.
Gao Y, Zheng H, Li L, Zhou C, Chen X, Zhou X, Cao Y
BioMed research international 2020;2020:6349312
BioMed research international 2020;2020:6349312
Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-α- and Interleukin-1β-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Oxygenase-1 Pathway.
Lv J, Liu Y, Jia S, Zhang Y, Tian H, Li J, Song H
Mediators of inflammation 2020;2020:6302391
Mediators of inflammation 2020;2020:6302391
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Feng LX, Zhao F, Liu Q, Peng JC, Duan XJ, Yan P, Wu X, Wang HS, Deng YH, Duan SB
Oxidative medicine and cellular longevity 2020;2020:6123459
Oxidative medicine and cellular longevity 2020;2020:6123459
RCC2 Expression Stimulates ER-Positive Breast Tumorigenesis.
Wang W, Xu B, Zhang Z, Fang K, Chang X
Journal of oncology 2020;2020:5619462
Journal of oncology 2020;2020:5619462
The Effect of MicroRNA-101 on Angiogenesis of Human Umbilical Vein Endothelial Cells during Hypoxia and in Mice with Myocardial Infarction.
Pang J, Ye L, Chen Q, Wang J, Yang X, He W, Hao L
BioMed research international 2020;2020:5426971
BioMed research international 2020;2020:5426971
Mesenchymal Stem Cells Activate the MEK/ERK Signaling Pathway and Enhance DNA Methylation via DNMT1 in PBMC from Systemic Lupus Erythematosus.
Xiong H, Guo Z, Tang Z, Ai X, Qi Q, Liu X, Huang D, Li Z, Ji S, Guo Q
BioMed research international 2020;2020:4174082
BioMed research international 2020;2020:4174082
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Kuang M, Yang M, Li L, Li C, Wang G
Oxidative medicine and cellular longevity 2020;2020:4045674
Oxidative medicine and cellular longevity 2020;2020:4045674
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Exerts Anti-Breast Cancer Effect via miR-200c-PDE7B/PD-L1-AKT/MAPK Axis.
Yang Y, Fang T, Cao YL, Lv YX, Chang QQ, Zhang DD
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3587095
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3587095
Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.
Cheng Y, Pan X, Wang J, Li X, Yang S, Yin R, Ma A, Zhu X
Oxidative medicine and cellular longevity 2020;2020:3186306
Oxidative medicine and cellular longevity 2020;2020:3186306
Akkermansia muciniphila Enhances the Antitumor Effect of Cisplatin in Lewis Lung Cancer Mice.
Chen Z, Qian X, Chen S, Fu X, Ma G, Zhang A
Journal of immunology research 2020;2020:2969287
Journal of immunology research 2020;2020:2969287
Ethanol Extract of the Infructescence of Platycarya strobilacea Sieb. et Zucc. Induces Methuosis of Human Nasopharyngeal Carcinoma Cells.
Liu J, Ying M, Wu B, Fu C
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2760979
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2760979
Combined Transplantation of Adipose Tissue-Derived Stem Cells and Endothelial Progenitor Cells Improve Diabetic Erectile Dysfunction in a Rat Model.
Yang Q, Chen W, Zhang C, Xie Y, Gao Y, Deng C, Sun X, Liu G, Deng C
Stem cells international 2020;2020:2154053
Stem cells international 2020;2020:2154053
Ginkgetin Alleviates Inflammation, Oxidative Stress, and Apoptosis Induced by Hypoxia/Reoxygenation in H9C2 Cells via Caspase-3 Dependent Pathway.
Liu X, Bian H, Dou QL, Huang XW, Tao WY, Liu WH, Li N, Zhang WW
BioMed research international 2020;2020:1928410
BioMed research international 2020;2020:1928410
Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40.
Song W, Lv Y, Tang Z, Nie F, Huang P, Pei Q, Guo R
Cardiovascular therapeutics 2020;2020:1795853
Cardiovascular therapeutics 2020;2020:1795853
Decoy Receptor 3 Promotes Preosteoclast Cell Death via Reactive Oxygen Species-Induced Fas Ligand Expression and the IL-1α/IL-1 Receptor Antagonist Pathway.
Peng YJ, Peng CT, Lin YH, Lin GJ, Huang SH, Chen SJ, Sytwu HK, Cheng CP
Mediators of inflammation 2020;2020:1237281
Mediators of inflammation 2020;2020:1237281
Aminooxy-Acetic Acid Inhibits Experimental Autoimmune Uveitis by Modulating the Balance between Effector and Regulatory Lymphocyte Subsets.
Mei S, Huang Y, Li N, Xu Z, Xu J, Dai Q, Wu J, Kijlstra A, Yang P, Hou S
Current molecular medicine 2020;20(8):624-632
Current molecular medicine 2020;20(8):624-632
ALKBH5-mediated m(6)A demethylation of lncRNA PVT1 plays an oncogenic role in osteosarcoma.
Chen S, Zhou L, Wang Y
Cancer cell international 2020;20:34
Cancer cell international 2020;20:34
miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6.
An Y, Zhang J, Cheng X, Li B, Tian Y, Zhang X, Zhao F
Cancer cell international 2020;20:237
Cancer cell international 2020;20:237
PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway.
Wu Q, Zhang B, Li B, Cao X, Chen X, Xue Q
Cancer cell international 2020;20:172
Cancer cell international 2020;20:172
Haploinsufficiency of TANK-binding kinase 1 prepones age-associated neuroinflammatory changes without causing motor neuron degeneration in aged mice.
Bruno C, Sieverding K, Freischmidt A, Satoh T, Walther P, Mayer B, Ludolph AC, Akira S, Yilmazer-Hanke D, Danzer KM, Lobsiger CS, Brenner D, Weishaupt JH
Brain communications 2020;2(2):fcaa133
Brain communications 2020;2(2):fcaa133
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
High-trans fatty acid and high-sugar diets can cause mice with non-alcoholic steatohepatitis with liver fibrosis and potential pathogenesis.
Xin X, Cai BY, Chen C, Tian HJ, Wang X, Hu YY, Feng Q
Nutrition & metabolism 2020;17:40
Nutrition & metabolism 2020;17:40
Gypenosides regulate farnesoid X receptor-mediated bile acid and lipid metabolism in a mouse model of non-alcoholic steatohepatitis.
Li H, Xi Y, Xin X, Tian H, Hu Y
Nutrition & metabolism 2020;17:34
Nutrition & metabolism 2020;17:34
miR-197-3p Represses the Proliferation of Prostate Cancer by Regulating the VDAC1/AKT/β-catenin Signaling Axis.
Huang Q, Ma B, Su Y, Chan K, Qu H, Huang J, Wang D, Qiu J, Liu H, Yang X, Wang Z
International journal of biological sciences 2020;16(8):1417-1426
International journal of biological sciences 2020;16(8):1417-1426
The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer.
Xu W, Huang M, Guo J, Zhang H, Wang D, Liu T, Liu H, Chen S, Gao P, Mu K
International journal of biological sciences 2020;16(8):1388-1402
International journal of biological sciences 2020;16(8):1388-1402
Septin4 promotes cell death in human colon cancer cells by interacting with BAX.
Zhao X, Feng H, Wang Y, Wu Y, Guo Q, Feng Y, Ma M, Guo W, Song X, Zhang Y, Han S, Cao L
International journal of biological sciences 2020;16(11):1917-1928
International journal of biological sciences 2020;16(11):1917-1928
Transcriptome sequencing revealed that knocking down FOXL2 affected cell proliferation, the cell cycle, and DNA replication in chicken pre-ovulatory follicle cells.
Luo W, Gu L, Li J, Gong Y
PloS one 2020;15(7):e0234795
PloS one 2020;15(7):e0234795
Microarray Analysis of Long Non-Coding RNAs in Lung Tissues of Patients with COPD and HOXA-AS2 Promotes HPMECs Proliferation via Notch1.
Zhou AY, Zhao YY, Zhou ZJ, Duan JX, Zhu YZ, Cai S, Chen P
International journal of chronic obstructive pulmonary disease 2020;15:2449-2460
International journal of chronic obstructive pulmonary disease 2020;15:2449-2460
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
Zhang G, Liu W, Wang R, Zhang Y, Chen L, Chen A, Luo H, Zhong H, Shao L
International journal of nanomedicine 2020;15:2419-2435
International journal of nanomedicine 2020;15:2419-2435
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Lin HY, Han HW, Wang YS, He DL, Sun WX, Feng L, Wen ZL, Yang MK, Lu GH, Wang XM, Qi JL, Yang YH
Chinese medicine 2020;15:23
Chinese medicine 2020;15:23
Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells.
Tong D, Ma Z, Su P, Wang S, Xu Y, Zhang LM, Wu Z, Liu K, Zhao P
Frontiers in cellular neuroscience 2020;14:590577
Frontiers in cellular neuroscience 2020;14:590577
RNA Binding Protein Motif 3 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Apoptosis Through Promoting Stress Granules Formation in PC12 Cells and Rat Primary Cortical Neurons.
Si W, Li Z, Huang Z, Ye S, Li X, Li Y, Kuang W, Chen D, Zhu M
Frontiers in cellular neuroscience 2020;14:559384
Frontiers in cellular neuroscience 2020;14:559384
Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy.
Li Y, Xiang J, Zhang J, Lin J, Wu Y, Wang X
Frontiers in cellular neuroscience 2020;14:555591
Frontiers in cellular neuroscience 2020;14:555591
Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis.
Kong J, Wang J, Gong X, Zheng X, Chen T
Drug design, development and therapy 2020;14:5521-5533
Drug design, development and therapy 2020;14:5521-5533
Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway.
Huang C, Zhang C, Yang P, Chao R, Yue Z, Li C, Guo J, Li M
Drug design, development and therapy 2020;14:4901-4913
Drug design, development and therapy 2020;14:4901-4913
Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo.
Wang H, Jiang Z, Pang Z, Zhou T, Gu Y
Drug design, development and therapy 2020;14:4801-4813
Drug design, development and therapy 2020;14:4801-4813
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
Wang MM, Zhang M, Feng YS, Xing Y, Tan ZX, Li WB, Dong F, Zhang F
Frontiers in cellular neuroscience 2020;14:134
Frontiers in cellular neuroscience 2020;14:134
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
Lin L, Wang D, Qu S, Zhao H, Lin Y
Drug design, development and therapy 2020;14:1127-1141
Drug design, development and therapy 2020;14:1127-1141
Prognostic roles of miR-124-3p and its target ANXA7 and their effects on cell migration and invasion in hepatocellular carcinoma.
Wang H, Mao J, Huang Y, Zhang J, Zhong L, Wu Y, Huang H, Yang J, Wei Y, Tang J
International journal of clinical and experimental pathology 2020;13(3):357-370
International journal of clinical and experimental pathology 2020;13(3):357-370
Linc01094 Accelerates the Growth and Metastatic-Related Traits of Glioblastoma by Sponging miR-126-5p.
Li XX, Yu Q
OncoTargets and therapy 2020;13:9917-9928
OncoTargets and therapy 2020;13:9917-9928
miR-137-3p Modulates the Progression of Prostate Cancer by Regulating the JNK3/EZH2 Axis.
Zang Y, Zhu J, Li Q, Tu J, Li X, Hu R, Yang D
OncoTargets and therapy 2020;13:7921-7932
OncoTargets and therapy 2020;13:7921-7932
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
Saleem MZ, Nisar MA, Alshwmi M, Din SRU, Gamallat Y, Khan M, Ma T
OncoTargets and therapy 2020;13:435-450
OncoTargets and therapy 2020;13:435-450
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Wu QQ, Zhao M, Huang GZ, Zheng ZN, Chen Y, Zeng WS, Lv XZ
OncoTargets and therapy 2020;13:2599-2611
OncoTargets and therapy 2020;13:2599-2611
Novel Alternatively Spliced Variants of Smad4 Expressed in TGF-β-Induced EMT Regulating Proliferation and Migration of A549 Cells.
Wan R, Xu X, Ma L, Chen Y, Tang L, Feng J
OncoTargets and therapy 2020;13:2203-2213
OncoTargets and therapy 2020;13:2203-2213
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells.
Gu L, Li Q, Liu H, Lu X, Zhu M
OncoTargets and therapy 2020;13:2007-2019
OncoTargets and therapy 2020;13:2007-2019
Herpes Simplex Virus 1-Induced Blood-Brain Barrier Damage Involves Apoptosis Associated With GM130-Mediated Golgi Stress.
He Q, Liu H, Huang C, Wang R, Luo M, Lu W
Frontiers in molecular neuroscience 2020;13:2
Frontiers in molecular neuroscience 2020;13:2
The Roles of Ubiquitination Factor E4B (UBE4B) in the Postoperative Prognosis of Patients with Renal Cell Carcinoma and in Renal Tumor Cells Growth and Metastasis.
Huang XQ, Hao S, Zhou ZQ, Huang B, Fang JY, Tang Y, Zhang JH, Xia JC
OncoTargets and therapy 2020;13:185-197
OncoTargets and therapy 2020;13:185-197
Lysophosphatidic Acid Induces Apoptosis of PC12 Cells Through LPA1 Receptor/LPA2 Receptor/MAPK Signaling Pathway.
Zhang J, Li Y, Wang C, Wang Y, Zhang Y, Huang L, Zhang Z
Frontiers in molecular neuroscience 2020;13:16
Frontiers in molecular neuroscience 2020;13:16
Antidepressant-Like Effect of Geniposide in Mice Exposed to a Chronic Mild Stress Involves the microRNA-298-5p-Mediated Nox1.
Zou T, Zhang J, Liu Y, Zhang Y, Sugimoto K, Mei C
Frontiers in molecular neuroscience 2020;13:131
Frontiers in molecular neuroscience 2020;13:131
Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.
Zheng D, Jiang C, Yan N, Miao Y, Wang K, Gao G, Jiao Y, Zhang X, He M, Yang Z
OncoTargets and therapy 2020;13:12649-12659
OncoTargets and therapy 2020;13:12649-12659
Dabigatran Suppresses PAR-1/SphK/S1P Activation of Astrocytes in Experimental Autoimmune Encephalomyelitis Model.
Chen R, Cao X, Luo W, Yang H, Luo X, Yu J, Luo J
Frontiers in molecular neuroscience 2020;13:114
Frontiers in molecular neuroscience 2020;13:114
IFI30 Is a Novel Immune-Related Target with Predicting Value of Prognosis and Treatment Response in Glioblastoma.
Zhu C, Chen X, Guan G, Zou C, Guo Q, Cheng P, Cheng W, Wu A
OncoTargets and therapy 2020;13:1129-1143
OncoTargets and therapy 2020;13:1129-1143
Ellagic acid inhibits cell proliferation, migration, and invasion in melanoma via EGFR pathway.
Wang F, Chen J, Xiang D, Lian X, Wu C, Quan J
American journal of translational research 2020;12(5):2295-2304
American journal of translational research 2020;12(5):2295-2304
4-hydroxy-2(3H)-benzoxazolone alleviates acetaminophen-induced hepatic injury by inhibiting NF-κB and activating Nrf2/HO-1 signaling pathways.
Wei X, Wang H, Sun X, Huang X, Xu W, Liang Y, Liu L, Mo S, Lin X, Lin J
American journal of translational research 2020;12(5):2169-2180
American journal of translational research 2020;12(5):2169-2180
N6-methyladenosine methyltransferase METTL3 promotes colorectal cancer cell proliferation through enhancing MYC expression.
Xiang S, Liang X, Yin S, Liu J, Xiang Z
American journal of translational research 2020;12(5):1789-1806
American journal of translational research 2020;12(5):1789-1806
Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-β/Smad3 signaling and promoting angiogenesis.
Zong J, Jiang J, Shi P, Liu J, Wang W, Li B, Zhao T, Pan T, Zhang Z, Bi L, Diao Y, Wang S
American journal of translational research 2020;12(2):478-492
American journal of translational research 2020;12(2):478-492
CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1.
Liu Y, Xia L, Dong L, Wang J, Xiao Q, Yu X, Zhu H
Cancer management and research 2020;12:921-929
Cancer management and research 2020;12:921-929
Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo.
Zang H, Li Y, Zhang X, Huang G
Cancer management and research 2020;12:7783-7795
Cancer management and research 2020;12:7783-7795
Deficiency of Mitochondrial Functions and Peroxidation of Frontoparietal Cortex Enhance Isoflurane Sensitivity in Aging Mice.
Gong C, Zhang D, Ou W, Ou M, Liang P, Liao D, Zhang W, Zhu T, Liu J, Zhou C
Frontiers in aging neuroscience 2020;12:583542
Frontiers in aging neuroscience 2020;12:583542
Circular RNA Circ-ZNF609 Promotes Lung Adenocarcinoma Proliferation by Modulating miR-1224-3p/ETV1 Signaling.
Zuo Y, Shen W, Wang C, Niu N, Pu J
Cancer management and research 2020;12:2471-2479
Cancer management and research 2020;12:2471-2479
Upregulation of DUSP14 Affects Proliferation, Invasion and Metastasis, Potentially via Epithelial-Mesenchymal Transition and Is Associated with Poor Prognosis in Pancreatic Cancer.
Wei Y, Wang G, Wang C, Zhou Y, Zhang J, Xu K
Cancer management and research 2020;12:2097-2108
Cancer management and research 2020;12:2097-2108
METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner.
Shi Y, Zhuang Y, Zhang J, Chen M, Wu S
Cancer management and research 2020;12:13173-13184
Cancer management and research 2020;12:13173-13184
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Mei Y, Cai D, Dai X
Journal of Cancer 2020;11(5):1162-1169
Journal of Cancer 2020;11(5):1162-1169
Metformin and LW6 impairs pancreatic cancer cells and reduces nuclear localization of YAP1.
Zhang X, Liu P, Shang Y, Kerndl H, Kumstel S, Gong P, Vollmar B, Zechner D
Journal of Cancer 2020;11(2):479-487
Journal of Cancer 2020;11(2):479-487
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
Zhang YY, Luo LM, Wang YX, Zhu N, Zhao TJ, Qin L
Journal of Cancer 2020;11(14):4261-4273
Journal of Cancer 2020;11(14):4261-4273
The M6A methyltransferase METTL3 promotes the development and progression of prostate carcinoma via mediating MYC methylation.
Yuan Y, Du Y, Wang L, Liu X
Journal of Cancer 2020;11(12):3588-3595
Journal of Cancer 2020;11(12):3588-3595
Analysis of lncRNA, miRNA and mRNA-associated ceRNA networks and identification of potential drug targets for drug-resistant non-small cell lung cancer.
Kong X, Hu S, Yuan Y, Du Y, Zhu Z, Song Z, Lu S, Zhao C, Yan D
Journal of Cancer 2020;11(11):3357-3368
Journal of Cancer 2020;11(11):3357-3368
MiR-200a Regulates Nasopharyngeal Carcinoma Cell Migration and Invasion by Targeting MYH10.
Liu W, Cai T, Li L, Chen H, Chen R, Zhang M, Zhang W, Zhao L, Xiong H, Qin P, Gao X, Jiang Q
Journal of Cancer 2020;11(10):3052-3060
Journal of Cancer 2020;11(10):3052-3060
P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition.
Cao Y, Han Q, Li J, Jia Y, Zhang R, Shi H
Journal of Cancer 2020;11(10):2788-2799
Journal of Cancer 2020;11(10):2788-2799
Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma.
Qin S, Yi M, Jiao D, Li A, Wu K
Journal of Cancer 2020;11(1):153-167
Journal of Cancer 2020;11(1):153-167
Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma.
Li Y, Chen R, Yang J, Mo S, Quek K, Kok CH, Cheng XD, Tian S, Zhang W, Qin JJ
Frontiers in genetics 2020;11:814
Frontiers in genetics 2020;11:814
Long Noncoding RNA TCONS_00016406 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating the miR-687/PTEN Pathway.
Liu X, Zhu N, Zhang B, Xu SB
Frontiers in physiology 2020;11:622
Frontiers in physiology 2020;11:622
Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis.
Ren S, Wei Y, Wang R, Wei S, Wen J, Yang T, Chen X, Wu S, Jing M, Li H, Wang M, Zhao Y
Frontiers in pharmacology 2020;11:600295
Frontiers in pharmacology 2020;11:600295
Astragalus Polysaccharides Inhibits Tumorigenesis and Lipid Metabolism Through miR-138-5p/SIRT1/SREBP1 Pathway in Prostate Cancer.
Guo S, Ma B, Jiang X, Li X, Jia Y
Frontiers in pharmacology 2020;11:598
Frontiers in pharmacology 2020;11:598
RNF183 Is a Prognostic Biomarker and Correlates With Tumor Purity, Immune Infiltrates in Uterine Corpus Endometrial Carcinoma.
Geng R, Zheng Y, Zhao L, Huang X, Qiang R, Zhang R, Guo X, Li R
Frontiers in genetics 2020;11:595733
Frontiers in genetics 2020;11:595733
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Yu Y, Wu DM, Li J, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
Frontiers in immunology 2020;11:593368
Frontiers in immunology 2020;11:593368
Bufei Jianpi Formula Improves Mitochondrial Function and Suppresses Mitophagy in Skeletal Muscle via the Adenosine Monophosphate-Activated Protein Kinase Pathway in Chronic Obstructive Pulmonary Disease.
Mao J, Li Y, Feng S, Liu X, Tian Y, Bian Q, Li J, Hu Y, Zhang L, Ji H, Li S
Frontiers in pharmacology 2020;11:587176
Frontiers in pharmacology 2020;11:587176
Lycopene Exerts Neuroprotective Effects After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the Nuclear Factor Erythroid-2 Related Factor 2/Nuclear Factor-κ-Gene Binding Pathway.
Fu C, Zheng Y, Zhu J, Chen B, Lin W, Lin K, Zhu J, Chen S, Li P, Fu X, Lin Z
Frontiers in pharmacology 2020;11:585898
Frontiers in pharmacology 2020;11:585898
Integrated Analysis of Key Genes and Pathways Involved in Fetal Growth Restriction and Their Associations With the Dysregulation of the Maternal Immune System.
Wang X, Zhu H, Lei L, Zhang Y, Tang C, Wu JX, Zhou JR, Xiao XR
Frontiers in genetics 2020;11:581789
Frontiers in genetics 2020;11:581789
Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils.
Lee J, Lu Y, Oshins R, West J, Moneypenny CG, Han K, Brantly ML
Frontiers in immunology 2020;11:574410
Frontiers in immunology 2020;11:574410
LncRNA NEAT1 Knockdown Inhibits Retinoblastoma Progression by miR-3619-5p/LASP1 Axis.
Chen X, Zhao S, Li Q, Xu C, Yu Y, Ge H
Frontiers in genetics 2020;11:574145
Frontiers in genetics 2020;11:574145
Long Non-coding RNA LINC01094 Promotes the Development of Clear Cell Renal Cell Carcinoma by Upregulating SLC2A3 via MicroRNA-184.
Xu H, Wang X, Wu J, Ji H, Chen Z, Guo H, Hou J
Frontiers in genetics 2020;11:562967
Frontiers in genetics 2020;11:562967
Soy Isoflavones Accelerate Glial Cell Migration via GPER-Mediated Signal Transduction Pathway.
Ariyani W, Miyazaki W, Amano I, Hanamura K, Shirao T, Koibuchi N
Frontiers in endocrinology 2020;11:554941
Frontiers in endocrinology 2020;11:554941
Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling.
Liu C, Chen K, Wang H, Zhang Y, Duan X, Xue Y, He H, Huang Y, Chen Z, Ren H, Wang H, Zeng C
Frontiers in pharmacology 2020;11:540479
Frontiers in pharmacology 2020;11:540479
Coix Seed Oil Exerts an Anti-Triple-Negative Breast Cancer Effect by Disrupting miR-205/S1PR1 Axis.
Fang T, Jiang YX, Chen L, Huang L, Tian XH, Zhou YD, Nagle DG, Zhang DD
Frontiers in pharmacology 2020;11:529962
Frontiers in pharmacology 2020;11:529962
An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid.
Ma C, Wang X, Xu T, Zhang S, Liu S, Zhai C, Wang Z, Mu J, Li C, Cheng F, Wang Q
Frontiers in pharmacology 2020;11:519
Frontiers in pharmacology 2020;11:519
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
Zhang K, Hussain T, Wang J, Li M, Wang W, Ma X, Liao Y, Yao J, Song Y, Liang Z, Zhou X, Xu L
Frontiers in microbiology 2020;11:433
Frontiers in microbiology 2020;11:433
TRIM59 Protects Mice From Sepsis by Regulating Inflammation and Phagocytosis in Macrophages.
Jin Z, Zhu Z, Liu S, Hou Y, Tang M, Zhu P, Tian Y, Li D, Yan D, Zhu X
Frontiers in immunology 2020;11:263
Frontiers in immunology 2020;11:263
LncRNA NEAT1 Targets Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via the miR-410-3p/YY1 Axis.
Wang Y, Hou L, Yuan X, Xu N, Zhao S, Yang L, Zhang N
Frontiers in immunology 2020;11:1975
Frontiers in immunology 2020;11:1975
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Lin Q, Zhou S, Huang Y, Huo Z, Chen C, Luo X, He J, Liu C, Zhang P
Frontiers in microbiology 2020;11:1745
Frontiers in microbiology 2020;11:1745
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Zhuang C, Liu G, Barkema HW, Zhou M, Xu S, Ur Rahman S, Liu Y, Kastelic JP, Gao J, Han B
Frontiers in microbiology 2020;11:1461
Frontiers in microbiology 2020;11:1461
MiR-224 Executes a Tumor Accelerative Role during Hepatocellular Carcinoma Malignancy by Targeting Cytoplasmic Polyadenylation Element-Binding Protein 3.
Miao K, Liu SD, Huang WX, Dong H
Pharmacology 2020;105(7-8):477-487
Pharmacology 2020;105(7-8):477-487
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Liu C, Ding R, Huang W, Miao L, Li J, Li Y
Pharmacology 2020;105(3-4):231-242
Pharmacology 2020;105(3-4):231-242
Metformin activates the STING/IRF3/IFN-β pathway by inhibiting AKT phosphorylation in pancreatic cancer.
Ren D, Qin G, Zhao J, Sun Y, Zhang B, Li D, Wang B, Jin X, Wu H
American journal of cancer research 2020;10(9):2851-2864
American journal of cancer research 2020;10(9):2851-2864
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial.
Zhao Z, Zhao Q, Gu B, Yin C, Shen K, Tang H, Xia H, Zhang X, Zhao Y, Yang X, Zhang Y
Theranostics 2020;10(8):3533-3545
Theranostics 2020;10(8):3533-3545
The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer.
Chou CW, Yang RY, Chan LC, Li CF, Sun L, Lee HH, Lee PC, Sher YP, Ying H, Hung MC
American journal of cancer research 2020;10(8):2621-2634
American journal of cancer research 2020;10(8):2621-2634
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Guo J, Zhou S, Huang P, Xu S, Zhang G, He H, Zeng Y, Xu CX, Kim H, Tan Y
American journal of cancer research 2020;10(6):1745-1760
American journal of cancer research 2020;10(6):1745-1760
Interferon regulatory factor-1 suppresses DNA damage response and reverses chemotherapy resistance by downregulating the expression of RAD51 in gastric cancer.
Tan L, Yuan J, Zhu W, Tao K, Wang G, Gao J
American journal of cancer research 2020;10(4):1255-1270
American journal of cancer research 2020;10(4):1255-1270
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
Bao W, Sun C, Sun X, He M, Yu H, Yan W, Wen F, Zhang L, Yang C
Theranostics 2020;10(25):11622-11636
Theranostics 2020;10(25):11622-11636
TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress.
Zhou K, Zheng Z, Li Y, Han W, Zhang J, Mao Y, Chen H, Zhang W, Liu M, Xie L, Zhang H, Xu H, Xiao J
Theranostics 2020;10(20):9280-9302
Theranostics 2020;10(20):9280-9302
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma.
Xu H, Wang H, Zhao W, Fu S, Li Y, Ni W, Xin Y, Li W, Yang C, Bai Y, Zhan M, Lu L
Theranostics 2020;10(13):5671-5686
Theranostics 2020;10(13):5671-5686
CEBPG promotes esophageal squamous cell carcinoma progression by enhancing PI3K-AKT signaling.
Huang Y, Lin L, Shen Z, Li Y, Cao H, Peng L, Qiu Y, Cheng X, Meng M, Lu D, Yin D
American journal of cancer research 2020;10(10):3328-3344
American journal of cancer research 2020;10(10):3328-3344
miR-483-3p, Mediated by KLF9, Functions as Tumor Suppressor in Testicular Seminoma via Targeting MMP9.
Zhang L, Ruan Y, Qin Z, Gao X, Xu K, Shi X, Gao S, Liu S, Zhu K, Wang W, Zuo L, Zhang L, Zhang W
Frontiers in oncology 2020;10:596574
Frontiers in oncology 2020;10:596574
Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling.
Wang L, Chai X, Wan R, Zhang H, Zhou C, Xiang L, Paul ME, Li Y
Frontiers in oncology 2020;10:595718
Frontiers in oncology 2020;10:595718
MicroRNA-1269a Promotes Proliferation and Arrest of Apoptosis of Glioma Cells by Directly Targeting ATRX.
Zhang Y, Wang Q, Luo N, Liu J, Ren H, Shao X, Zhang L, Yu Y
Frontiers in oncology 2020;10:563901
Frontiers in oncology 2020;10:563901
LL-37-Induced Autophagy Contributed to the Elimination of Live Porphyromonas gingivalis Internalized in Keratinocytes.
Yang X, Niu L, Pan Y, Feng X, Liu J, Guo Y, Pan C, Geng F, Tang X
Frontiers in cellular and infection microbiology 2020;10:561761
Frontiers in cellular and infection microbiology 2020;10:561761
siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.
Li P, Cao G, Huang Y, Wu W, Chen B, Wang Z, Xiong M
Frontiers in oncology 2020;10:541262
Frontiers in oncology 2020;10:541262
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Wu Y, Chen X, Dong W, Xu Z, Jian Y, Xu C, Zhang L, Wei A, Yu X, Wang S, Wang Y, Liu G, Sun X, Wang S
Frontiers in oncology 2020;10:540332
Frontiers in oncology 2020;10:540332
Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways.
Shi CX, Wang Y, Chen Q, Jiao FZ, Pei MH, Gong ZJ
Frontiers in cellular and infection microbiology 2020;10:196
Frontiers in cellular and infection microbiology 2020;10:196
FGF18 Inhibits Clear Cell Renal Cell Carcinoma Proliferation and Invasion via Regulating Epithelial-Mesenchymal Transition.
Yang C, Zhang Z, Ye F, Mou Z, Chen X, Ou Y, Xu C, Wu S, Cheng Z, Hu J, Zou L, Jiang H
Frontiers in oncology 2020;10:1685
Frontiers in oncology 2020;10:1685
Silencing of LncRNA C1RL-AS1 Suppresses the Malignant Phenotype in Gastric Cancer Cells via the AKT/β-Catenin/c-Myc Pathway.
Zhen-Hua W, Yi-Wei G, Li-Qin Z, Jie-Yun Z, Zhe G, Wei-Jian G
Frontiers in oncology 2020;10:1508
Frontiers in oncology 2020;10:1508
Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down-Regulating PI3K/AKT Signaling Pathway.
Lin K, Rong Y, Chen D, Zhao Z, Bo H, Qiao A, Hao X, Wang J
Frontiers in oncology 2020;10:141
Frontiers in oncology 2020;10:141
PD-L1 Under Regulation of miR-429 Influences the Sensitivity of Gastric Cancer Cells to TRAIL by Binding of EGFR.
Lv J, Guo T, Qu X, Che X, Li C, Wang S, Gong J, Wu P, Liu Y, Liu Y, Xu L
Frontiers in oncology 2020;10:1067
Frontiers in oncology 2020;10:1067
Natural Polyketides Isolated from the Endophytic Fungus Phomopsis sp. CAM212 with a Semisynthetic Derivative Downregulating the ERK/IκBα Signaling Pathways.
Jouda JB, Njoya EM, Fobofou SAT, Zhou ZY, Qiang Z, Mbazoa CD, Brandt W, Zhang GL, Wandji J, Wang F
Planta medica 2020 Sep;86(13-14):1032-1042
Planta medica 2020 Sep;86(13-14):1032-1042
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
Wu Y, Wang Z, Fu X, Lin Z, Yu K
International immunopharmacology 2020 Sep;86:106713
International immunopharmacology 2020 Sep;86:106713
Obesity-Induced Increase in Cystatin C Alleviates Tissue Inflammation.
Dedual MA, Wueest S, Challa TD, Lucchini FC, Aeppli TRJ, Borsigova M, Mauracher AA, Vavassori S, Pachlopnik Schmid J, Blüher M, Konrad D
Diabetes 2020 Sep;69(9):1927-1935
Diabetes 2020 Sep;69(9):1927-1935
KLHL22 promotes malignant melanoma growth in vitro and in vivo by activating the PI3K/Akt/mTOR signaling pathway.
Liu XR, Wang W, Li HM
Neoplasma 2020 Sep;67(5):1106-1113
Neoplasma 2020 Sep;67(5):1106-1113
A novel m.11406 T > A mutation in mitochondrial ND4 gene causes MELAS syndrome.
Lin Y, Xu X, Zhao D, Liu F, Luo Y, Du J, Wang D, Ji K, Zhao Y, Yan C
Mitochondrion 2020 Sep;54:57-64
Mitochondrion 2020 Sep;54:57-64
HAP1 Modulates Epileptic Seizures by Regulating GABA(A)R Function in Patients with Temporal Lobe Epilepsy and in the PTZ-Induced Epileptic Model.
Li R, Wu B, He M, Zhang P, Zhang Q, Deng J, Yuan J, Chen Y
Neurochemical research 2020 Sep;45(9):1997-2008
Neurochemical research 2020 Sep;45(9):1997-2008
E2F7, regulated by miR‑30c, inhibits apoptosis and promotes cell cycle of prostate cancer cells.
Wang Y, Pei X, Xu P, Tan Z, Zhu Z, Zhang G, Jiang Z, Deng Z
Oncology reports 2020 Sep;44(3):849-862
Oncology reports 2020 Sep;44(3):849-862
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
Zhang N, Zhang Y, Qian H, Wu S, Cao L, Sun Y
Cell death and differentiation 2020 Sep;27(9):2605-2619
Cell death and differentiation 2020 Sep;27(9):2605-2619
Negative feedback loop of ERK/CREB/miR-212-3p inhibits HBeAg-induced macrophage activation.
Chen W, Bian H, Xie X, Yang X, Bi B, Li C, Zhang Y, Zhu Q, Song J, Qin C, Qi J
Journal of cellular and molecular medicine 2020 Sep;24(18):10935-10945
Journal of cellular and molecular medicine 2020 Sep;24(18):10935-10945
Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral bone.
Hu Y, Wu H, Xu T, Wang Y, Qin H, Yao Z, Chen P, Xie Y, Ji Z, Yang K, Chai Y, Zhang X, Yu B, Cui Z
Journal of orthopaedic translation 2020 Sep;24:12-22
Journal of orthopaedic translation 2020 Sep;24:12-22
MicroRNA‑199a‑5p suppresses cell proliferation, migration and invasion by targeting ITGA3 in colorectal cancer.
Tian L, Chen M, He Q, Yan Q, Zhai C
Molecular medicine reports 2020 Sep;22(3):2307-2317
Molecular medicine reports 2020 Sep;22(3):2307-2317
KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-β/SMAD signaling pathway.
Li Y, Yang J, Zhang X, Liu H, Guo J
Experimental and therapeutic medicine 2020 Sep;20(3):2774-2782
Experimental and therapeutic medicine 2020 Sep;20(3):2774-2782
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
Yang Q, Zhao Y, Chen Y, Chang Y, Huang A, Xu T, Li G, Wu G
Oncology letters 2020 Sep;20(3):2387-2395
Oncology letters 2020 Sep;20(3):2387-2395
MicroRNA-19a-3p inhibits the cellular proliferation and invasion of non-small cell lung cancer by downregulating UBAP2L.
Pan Y, Jin K, Xie X, Wang K, Zhang H
Experimental and therapeutic medicine 2020 Sep;20(3):2252-2261
Experimental and therapeutic medicine 2020 Sep;20(3):2252-2261
circANRIL reduces vascular endothelial injury, oxidative stress and inflammation in rats with coronary atherosclerosis.
Shi P, Ji H, Zhang H, Yang J, Guo R, Wang J
Experimental and therapeutic medicine 2020 Sep;20(3):2245-2251
Experimental and therapeutic medicine 2020 Sep;20(3):2245-2251
BAG5 promotes invasion of papillary thyroid cancer cells via upregulation of fibronectin 1 at the translational level.
Zhang DL, Wang JM, Wu T, Du X, Yan J, Du ZX, Wang HQ
Biochimica et biophysica acta. Molecular cell research 2020 Sep;1867(9):118715
Biochimica et biophysica acta. Molecular cell research 2020 Sep;1867(9):118715
TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.
Liu Q, Zhu L, Liu X, Zheng J, Liu Y, Ruan X, Cao S, Cai H, Li Z, Xue Y
RNA biology 2020 Sep;17(9):1293-1308
RNA biology 2020 Sep;17(9):1293-1308
A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma.
Xu J, Zhang M, Lin X, Wang Y, He X
Steroids 2020 Sep;161:108672
Steroids 2020 Sep;161:108672
Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway.
Ju L, Hu P, Chen P, Xue X, Li Z, He F, Qiu Z, Cheng J, Huang F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110471
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110471
PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway.
Zhou YQ, Liu DQ, Chen SP, Chen N, Sun J, Wang XM, Li DY, Tian YK, Ye DW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110356
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110356
Fetal bovine serum-derived exosomes regulate the adipogenic differentiation of human bone marrow mesenchymal stromal cells in a cross-species manner.
Zhou Q, Xie F, Zhou B, Li C, Kang Y, Wu B, Li L, Dai R
Differentiation; research in biological diversity 2020 Sep-Oct;115:11-21
Differentiation; research in biological diversity 2020 Sep-Oct;115:11-21
LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway.
Liu Y, Ma L, Shangguan F, Zhao X, Wang W, Gao Z, Zhou H, Qu G, Huang Y, An J, Xue J, Yang S, Cao Q
Aging 2020 Sep 5;12(16):16142-16154
Aging 2020 Sep 5;12(16):16142-16154
Emodin protects against intestinal and lung injury induced by acute intestinal injury by modulating SP-A and TLR4/NF-κB pathway.
Qian J, Li G, Jin X, Ma C, Cai W, Jiang N, Zheng J
Bioscience reports 2020 Sep 30;40(9)
Bioscience reports 2020 Sep 30;40(9)
Multifactorial Attenuation of the Murine Heat Shock Response With Age.
Jurivich DA, Manocha GD, Trivedi R, Lizakowski M, Rakoczy S, Brown-Borg H
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Sep 25;75(10):1846-1852
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Sep 25;75(10):1846-1852
AXL Inactivation Inhibits Mesothelioma Growth and Migration via Regulation of p53 Expression.
Song W, Wang H, Lu M, Ni X, Bahri N, Zhu S, Chen L, Wu Y, Qiu J, Fletcher JA, Ou WB
Cancers 2020 Sep 25;12(10)
Cancers 2020 Sep 25;12(10)
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Jiang TY, Pan YF, Wan ZH, Lin YK, Zhu B, Yuan ZG, Ma YH, Shi YY, Zeng TM, Dong LW, Tan YX, Wang HY
Science translational medicine 2020 Sep 23;12(562)
Science translational medicine 2020 Sep 23;12(562)
Circular RNA GLIS2 promotes colorectal cancer cell motility via activation of the NF-κB pathway.
Chen J, Yang X, Liu R, Wen C, Wang H, Huang L, Li W, Zhu Z, Zhu Y, Liu H
Cell death & disease 2020 Sep 23;11(9):788
Cell death & disease 2020 Sep 23;11(9):788
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Yang Y, Wang Q, Song D, Zen R, Zhang L, Wang Y, Yang H, Zhang D, Jia J, Zhang J, Wang J
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Manganese exposure caused reproductive toxicity of male mice involving activation of GnRH secretion in the hypothalamus by prostaglandin E2 receptors EP1 and EP2.
Wu F, Yang H, Liu Y, Yang X, Xu B, Liu W, Xu Z, Deng Y
Ecotoxicology and environmental safety 2020 Sep 15;201:110712
Ecotoxicology and environmental safety 2020 Sep 15;201:110712
Regulatory effects of the Uty/Ddx3y locus on neighboring chromosome Y genes and autosomal mRNA transcripts in adult mouse non-reproductive cells.
Deschepper CF
Scientific reports 2020 Sep 10;10(1):14900
Scientific reports 2020 Sep 10;10(1):14900
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Yuan M, Yang X, Duscher D, Xiong H, Ren S, Xu X, Wang C, Chen J, Liu Y, Machens HG, Chen Z
Life sciences 2020 Sep 1;256:118022
Life sciences 2020 Sep 1;256:118022
MicroRNA-92a serves as a risk factor in sepsis-induced ARDS and regulates apoptosis and cell migration in lipopolysaccharide-induced HPMEC and A549 cell injury.
Xu F, Yuan J, Tian S, Chen Y, Zhou F
Life sciences 2020 Sep 1;256:117957
Life sciences 2020 Sep 1;256:117957
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, Bai X, Liu D, Wang Z
Acta biomaterialia 2020 Sep 1;113:597-613
Acta biomaterialia 2020 Sep 1;113:597-613
Time-resolved mRNA and miRNA expression profiling reveals crucial coregulation of molecular pathways involved in epithelial-pneumococcal interactions.
Li H, Lin L, Chong L, Gu S, Wen S, Yu G, Hu X, Dong L, Zhang H, Li C
Immunology and cell biology 2020 Oct;98(9):726-742
Immunology and cell biology 2020 Oct;98(9):726-742
Galectin-3 inhibition attenuates doxorubicin-induced cardiac dysfunction by upregulating the expression of peroxiredoxin-4.
Tian Y, Lv W, Lu C, Jiang Y, Yang X, Song M
Canadian journal of physiology and pharmacology 2020 Oct;98(10):700-707
Canadian journal of physiology and pharmacology 2020 Oct;98(10):700-707
Tetrandrine sensitizes nasopharyngeal carcinoma cells to irradiation by inducing autophagy and inhibiting MEK/ERK pathway.
Wang J, Yao Z, Lai X, Bao H, Li Y, Li S, Chang L, Zhang G
Cancer medicine 2020 Oct;9(19):7268-7278
Cancer medicine 2020 Oct;9(19):7268-7278
Downregulation of PER2 Promotes Tumor Progression by Enhancing Glycolysis via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Oral Squamous Cell Carcinoma.
Long W, Gong X, Yang Y, Yang K
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2020 Oct;78(10):1780.e1-1780.e14
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2020 Oct;78(10):1780.e1-1780.e14
TRADES: Targeted RNA Demethylation by SunTag System.
Mo J, Chen Z, Qin S, Li S, Liu C, Zhang L, Ran R, Kong Y, Wang F, Liu S, Zhou Y, Zhang X, Weng X, Zhou X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Oct;7(19):2001402
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Oct;7(19):2001402
Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver.
Zhao M, Zhao H, Lin L, Wang Y, Chen M, Wu B
Xenobiotica; the fate of foreign compounds in biological systems 2020 Oct;50(10):1139-1148
Xenobiotica; the fate of foreign compounds in biological systems 2020 Oct;50(10):1139-1148
SUMOylation of HSP27 regulates PKM2 to promote esophageal squamous cell carcinoma progression.
Zhang X, Liu T, Zheng S, Liu Q, Shen T, Han X, Zhang Q, Yang L, Lu X
Oncology reports 2020 Oct;44(4):1355-1364
Oncology reports 2020 Oct;44(4):1355-1364
LINC01419 promotes cell proliferation and metastasis in hepatocellular carcinoma by enhancing NDRG1 promoter activity.
Dang H, Chen L, Tang P, Cai X, Zhang W, Zhang R, Huang A, Tang H
Cellular oncology (Dordrecht, Netherlands) 2020 Oct;43(5):931-947
Cellular oncology (Dordrecht, Netherlands) 2020 Oct;43(5):931-947
Azidothymidine (AZT) Inhibits Proliferation of Human Ovarian Cancer Cells by Regulating Cell Cycle Progression.
Hsieh Y, Tseng JJ
Anticancer research 2020 Oct;40(10):5517-5527
Anticancer research 2020 Oct;40(10):5517-5527
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
Yang ZH, Li J, Chen WZ, Kong FS
Cell biochemistry and function 2020 Oct;38(7):943-954
Cell biochemistry and function 2020 Oct;38(7):943-954
Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.
Wang LJ, Cai HQ
The Kaohsiung journal of medical sciences 2020 Oct;36(10):775-785
The Kaohsiung journal of medical sciences 2020 Oct;36(10):775-785
The carboxyl-terminal di-lysine motif is essential for catalytic activity of UDP-glucuronosyltransferase 1A9.
Miyauchi Y, Kurohara K, Kimura A, Esaki M, Fujimoto K, Hirota Y, Takechi S, Mackenzie PI, Ishii Y, Tanaka Y
Drug metabolism and pharmacokinetics 2020 Oct;35(5):466-474
Drug metabolism and pharmacokinetics 2020 Oct;35(5):466-474
CaMK4-dependent phosphorylation of Akt/mTOR underlies Th17 excessive activation in experimental autoimmune prostatitis.
Zhan CS, Chen J, Chen J, Zhang LG, Liu Y, Du HX, Wang H, Zheng MJ, Yu ZQ, Chen XG, Zhang L, Liang CZ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):14006-14023
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):14006-14023
MicroRNA-338 in MSCs-derived exosomes inhibits cardiomyocyte apoptosis in myocardial infarction.
Fu DL, Jiang H, Li CY, Gao T, Liu MR, Li HW
European review for medical and pharmacological sciences 2020 Oct;24(19):10107-10117
European review for medical and pharmacological sciences 2020 Oct;24(19):10107-10117
Activated FMS-like tyrosine kinase 3 ameliorates angiotensin II-induced cardiac remodelling.
Ma W, Liang F, Zhan H, Jiang X, Gao C, Zhang X, Zhang K, Sun Q, Hu H, Zhao Z
Acta physiologica (Oxford, England) 2020 Oct;230(2):e13519
Acta physiologica (Oxford, England) 2020 Oct;230(2):e13519
Intranasal administration of Cytoglobin modifies human umbilical cord‑derived mesenchymal stem cells and improves hypoxic‑ischemia brain damage in neonatal rats by modulating p38 MAPK signaling‑mediated apoptosis.
Yang H, Tian S, Xie L, Chen Y, Ma L
Molecular medicine reports 2020 Oct;22(4):3493-3503
Molecular medicine reports 2020 Oct;22(4):3493-3503
Roseburia intestinalis‑derived flagellin ameliorates colitis by targeting miR‑223‑3p‑mediated activation of NLRP3 inflammasome and pyroptosis.
Wu X, Pan S, Luo W, Shen Z, Meng X, Xiao M, Tan B, Nie K, Tong T, Wang X
Molecular medicine reports 2020 Oct;22(4):2695-2704
Molecular medicine reports 2020 Oct;22(4):2695-2704
Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis.
Tao Q, Wang X, Liu L, Ji Y, Luo Q, Du J, Yu L, Shen J, Chu D
Acta tropica 2020 Oct;210:105560
Acta tropica 2020 Oct;210:105560
Members of the miR-30 family inhibit the epithelial-to-mesenchymal transition of non-small-cell lung cancer cells by suppressing XB130 expression levels.
Song K, Jiang Y, Zhao Y, Xie Y, Zhou J, Yu W, Wang Q
Oncology letters 2020 Oct;20(4):68
Oncology letters 2020 Oct;20(4):68
Inhibitory effect of Lycium barbarum polysaccharide on sperm damage during cryopreservation.
Yan B, Zhang X, Wang J, Jia S, Zhou Y, Tian J, Wang H, Tang Y
Experimental and therapeutic medicine 2020 Oct;20(4):3051-3063
Experimental and therapeutic medicine 2020 Oct;20(4):3051-3063
Long non-coding RNA MEG3 promotes cataractogenesis by upregulating TP53INP1 expression in age-related cataract.
Tu Y, Xie L, Chen L, Yuan Y, Qin B, Wang K, Zhu Q, Ji N, Zhu M, Guan H
Experimental eye research 2020 Oct;199:108185
Experimental eye research 2020 Oct;199:108185
β-estradiol adjusts intestinal function via ERβ and GPR30 mediated PI3K/AKT signaling activation to alleviate postmenopausal dyslipidemia.
Meng Q, Li J, Chao Y, Bi Y, Zhang W, Zhang Y, Ji T, Fu Y, Chen Q, Zhang Q, Li Y, Bian H
Biochemical pharmacology 2020 Oct;180:114134
Biochemical pharmacology 2020 Oct;180:114134
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Kong H, He J, Guo S, Song Q, Xiang D, Tao R, Yu H, Chen G, Huang Z, Ning Q, Huang J
PLoS pathogens 2020 Oct;16(10):e1008947
PLoS pathogens 2020 Oct;16(10):e1008947
Liraglutide, a glucagon-like peptide-1 receptor agonist, suppresses osteoclastogenesis through the inhibition of NF-κB and MAPK pathways via GLP-1R.
Li Z, Li S, Wang N, Xue P, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110523
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110523
S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway.
Shao Z, Pan Z, Lin J, Zhao Q, Wang Y, Ni L, Feng S, Tian N, Wu Y, Sun L, Gao W, Zhou Y, Zhang X, Wang X
Aging 2020 Oct 7;12(19):19254-19272
Aging 2020 Oct 7;12(19):19254-19272
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer.
Li J, Xie H, Ying Y, Chen H, Yan H, He L, Xu M, Xu X, Liang Z, Liu B, Wang X, Zheng X, Xie L
Molecular cancer 2020 Oct 29;19(1):152
Molecular cancer 2020 Oct 29;19(1):152
Regulatory coupling between long noncoding RNAs and senescence in irradiated microglia.
Xu A, Li R, Ren A, Jian H, Huang Z, Zeng Q, Wang B, Zheng J, Chen X, Zheng N, Zheng R, Tian Y, Liu M, Mao Z, Ji A, Yuan Y
Journal of neuroinflammation 2020 Oct 28;17(1):321
Journal of neuroinflammation 2020 Oct 28;17(1):321
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Lu J, Meng Z, Chen Y, Yu L, Gao B, Zheng Y, Guan S
Food & function 2020 Oct 21;11(10):9208-9215
Food & function 2020 Oct 21;11(10):9208-9215
Circulating miR-27a-3p as a candidate for a biomarker of whole grain diets for lipid metabolism.
Liu J, Li Y, Xue L, Fan M, Nie C, Wang Y, Zhang H, Qian H, Wang L
Food & function 2020 Oct 21;11(10):8852-8865
Food & function 2020 Oct 21;11(10):8852-8865
Loss of RAD6B induces degeneration of the cochlea in mice.
Ma Y, Song Y, Shen R, Li P, Ding H, Guo Z, Liu X, Wang D
Biochemical and biophysical research communications 2020 Oct 20;531(3):402-408
Biochemical and biophysical research communications 2020 Oct 20;531(3):402-408
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice.
Zhao J, Xie C, Wang K, Takahashi S, Krausz KW, Lu D, Wang Q, Luo Y, Gong X, Mu X, Wang Q, Su S, Gonzalez FJ
Toxicology letters 2020 Oct 15;333:290-302
Toxicology letters 2020 Oct 15;333:290-302
Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level.
Song W, Gao K, Huang P, Tang Z, Nie F, Jia S, Guo R
Life sciences 2020 Oct 15;259:118397
Life sciences 2020 Oct 15;259:118397
Connecting METTL3 and intratumoural CD33(+) MDSCs in predicting clinical outcome in cervical cancer.
Ni HH, Zhang L, Huang H, Dai SQ, Li J
Journal of translational medicine 2020 Oct 15;18(1):393
Journal of translational medicine 2020 Oct 15;18(1):393
Long noncoding RNA Linc00337 functions as an E2F1 co-activator and promotes cell proliferation in pancreatic ductal adenocarcinoma.
Wang H, Yu S, Peng H, Shu Y, Zhang W, Zhu Q, Wu Y, Xu Y, Yan J, Xiang H
Journal of experimental & clinical cancer research : CR 2020 Oct 14;39(1):216
Journal of experimental & clinical cancer research : CR 2020 Oct 14;39(1):216
Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.
Ebokaiwe AP, Njoya EM, Sheng Y, Zhang Z, Li S, Zhou Z, Qiang Z, Peng T, Hussein AA, Zhang G, Lu X, Li L, Wang F
Toxicology and applied pharmacology 2020 Oct 1;404:115203
Toxicology and applied pharmacology 2020 Oct 1;404:115203
Galectin-3 mediates high-glucose-induced cardiomyocyte injury by the NADPH oxidase/reactive oxygen species pathway.
Sun J, Zhang L, Fang J, Yang S, Chen L
Canadian journal of physiology and pharmacology 2020 Nov;98(11):826-833
Canadian journal of physiology and pharmacology 2020 Nov;98(11):826-833
Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma.
Hong X, Jiang F, Li Y, Fang L, Qian Z, Chen H, Kong R
International immunopharmacology 2020 Nov;88:106988
International immunopharmacology 2020 Nov;88:106988
The mechanism of Arhalofenate in alleviating hyperuricemia-Activating PPARγ thereby reducing caspase-1 activity.
Wang G, Zuo T, Li R
Drug development research 2020 Nov;81(7):859-866
Drug development research 2020 Nov;81(7):859-866
Blocking P2X7-Mediated Macrophage Polarization Overcomes Treatment Resistance in Lung Cancer.
Qin J, Zhang X, Tan B, Zhang S, Yin C, Xue Q, Zhang Z, Ren H, Chen J, Liu M, Qian M, Du B
Cancer immunology research 2020 Nov;8(11):1426-1439
Cancer immunology research 2020 Nov;8(11):1426-1439
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Pyrrolidinedithiocarbamic Acid Ammonium Salt Inhibits Apoptosis and Phenotypic Transformation of Co-Culture of Myeloma Cells and Renal Tubular Epithelial Cells by Reducing the Secretion of Light Chain Protein.
Yu X, Bao J, Cui X, DU F, Wang Y, Bi L, Sun J, Li L
Iranian journal of public health 2020 Nov;49(11):2078-2086
Iranian journal of public health 2020 Nov;49(11):2078-2086
Transcription factor Kruppel-like factor 5 positively regulates the expression of AarF domain containing kinase 4.
Chen X, Liu S, Chen J, Wang X, Zhou G
Molecular biology reports 2020 Nov;47(11):8419-8427
Molecular biology reports 2020 Nov;47(11):8419-8427
N‑Myc induces the tumor progression of prostate cancer by regulating FSCN1.
He G, Li M, Fang L, Xu L, Huang X, Zheng L, Yang L, Luo W, Cai Y, Ma W, Liang C, Yin Y
Oncology reports 2020 Nov;44(5):2265-2274
Oncology reports 2020 Nov;44(5):2265-2274
Anti‑proliferative effect of honokiol on SW620 cells through upregulating BMP7 expression via the TGF‑β1/p53 signaling pathway.
Li Q, Ma Y, Liu XL, Mu L, He BC, Wu K, Sun WJ
Oncology reports 2020 Nov;44(5):2093-2107
Oncology reports 2020 Nov;44(5):2093-2107
lncRNA RASSF8‑AS1 suppresses the progression of laryngeal squamous cell carcinoma via targeting the miR‑664b‑3p/TLE1 axis.
Liu T, Meng W, Cao H, Chi W, Zhao L, Cui W, Yin H, Wang B
Oncology reports 2020 Nov;44(5):2031-2044
Oncology reports 2020 Nov;44(5):2031-2044
Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide.
Yan L, Jiaqiong L, Yue G, Xiaoyong L, Xuexian T, Ming L, Yinglan L, Xinxue L, Zena H
Renal failure 2020 Nov;42(1):270-281
Renal failure 2020 Nov;42(1):270-281
Inhibition of α1-adrenoceptor reduces TGF-β1-induced epithelial-to-mesenchymal transition and attenuates UUO-induced renal fibrosis in mice.
Ren H, Zuo S, Hou Y, Shang W, Liu N, Yin Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14892-14904
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14892-14904
Pharmacological Effects of Fasudil on Flap Survival in a Rodent Model.
Ji E, Wang J, Wang L, Pan Z, Gao W
The Journal of surgical research 2020 Nov;255:575-582
The Journal of surgical research 2020 Nov;255:575-582
Functional variation of SLC52A3 rs13042395 predicts survival of Chinese gastric cancer patients.
Qu X, Cheng L, Zhao L, Qiu L, Guo W
Journal of cellular and molecular medicine 2020 Nov;24(21):12550-12559
Journal of cellular and molecular medicine 2020 Nov;24(21):12550-12559
MiRNA-1 promotes pyroptosis of cardiomyocytes and release of inflammatory factors by downregulating the expression level of PIK3R1 through the FoxO3a pathway.
Yao RD, Li HL, Liu Y, Sun LT
European review for medical and pharmacological sciences 2020 Nov;24(21):11243-11250
European review for medical and pharmacological sciences 2020 Nov;24(21):11243-11250
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Song J, Zhu XM, Wei QY
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
Melatonin inhibits Müller cell activation and pro-inflammatory cytokine production via upregulating the MEG3/miR-204/Sirt1 axis in experimental diabetic retinopathy.
Tu Y, Zhu M, Wang Z, Wang K, Chen L, Liu W, Shi Q, Zhao Q, Sun Y, Wang X, Song E, Liu X
Journal of cellular physiology 2020 Nov;235(11):8724-8735
Journal of cellular physiology 2020 Nov;235(11):8724-8735
Specific inhibition of FAK signaling attenuates subchondral bone deterioration and articular cartilage degeneration during osteoarthritis pathogenesis.
Wu H, Xu T, Chen Z, Wang Y, Li K, Chen PS, Yao Z, Su J, Cheng C, Wu X, Zhang H, Chai Y, Zhang X, Hu Y, Yu B, Cui Z
Journal of cellular physiology 2020 Nov;235(11):8653-8666
Journal of cellular physiology 2020 Nov;235(11):8653-8666
ITCH regulates oxidative stress induced by high glucose through thioredoxin interacting protein in cultured human lens epithelial cells.
Jiang L, Zhou W, Lu B, Yan Q
Molecular medicine reports 2020 Nov;22(5):4307-4319
Molecular medicine reports 2020 Nov;22(5):4307-4319
Reduced IκBα promotes hepatocellular carcinoma cell proliferation and migration via regulation of NF-κB/Erbin axis.
Tan Y, Lin XT, Luo YD, Zhang J, Fang L, Zhu YY, Yu HQ, Shuai L, Jiang Y, Zhang LD, Bie P, Xie CM
Oncology letters 2020 Nov;20(5):216
Oncology letters 2020 Nov;20(5):216
Combined effect of recombinant human adenovirus p53 and curcumin in the treatment of liver cancer.
Qu J, Lu W, Chen M, Gao W, Zhang C, Guo B, Yang J
Experimental and therapeutic medicine 2020 Nov;20(5):18
Experimental and therapeutic medicine 2020 Nov;20(5):18
Effects of various levels of dietary fiber on carcass traits, meat quality and myosin heavy chain I, IIa, IIx and IIb expression in muscles in Erhualian and Large White pigs.
Han P, Li P, Zhou W, Fan L, Wang B, Liu H, Gao C, Du T, Pu G, Wu C, Zhang Z, Niu P, Huang R, Li H
Meat science 2020 Nov;169:108160
Meat science 2020 Nov;169:108160
Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8-miR-10b-5p-WWC3 pathway.
Yang Y, Liu X, Zheng J, Xue Y, Liu L, Ma J, Wang P, Yang C, Wang D, Shao L, Ruan X, Liu Y
Molecular oncology 2020 Nov;14(11):2936-2959
Molecular oncology 2020 Nov;14(11):2936-2959
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Liu Y, Zhou M, Xu S, Khan MA, Shi Y, Qu W, Gao J, Liu G, Kastelic JP, Han B
Journal of dairy science 2020 Nov;103(11):10429-10445
Journal of dairy science 2020 Nov;103(11):10429-10445
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
Deficiency of Notch signaling in pericytes results in arteriovenous malformations.
Nadeem T, Bogue W, Bigit B, Cuervo H
JCI insight 2020 Nov 5;5(21)
JCI insight 2020 Nov 5;5(21)
Asymmetrical effects of deafness-associated mitochondrial DNA 7516delA mutation on the processing of RNAs in the H-strand and L-strand polycistronic transcripts.
Xiao Y, Wang M, He Q, Xu L, Zhang Q, Meng F, Jia Z, Zhang F, Wang H, Guan MX
Nucleic acids research 2020 Nov 4;48(19):11113-11129
Nucleic acids research 2020 Nov 4;48(19):11113-11129
Expression and prognostic analyses of the insulin-like growth factor 2 mRNA binding protein family in human pancreatic cancer.
Cui XH, Hu SY, Zhu CF, Qin XH
BMC cancer 2020 Nov 27;20(1):1160
BMC cancer 2020 Nov 27;20(1):1160
Therapeutic evaluation of palbociclib and its compatibility with other chemotherapies for primary and recurrent nasopharyngeal carcinoma.
Xue Z, Lui VWY, Li Y, Jia L, You C, Li X, Piao W, Yuan H, Khong PL, Lo KW, Cheung LWT, Lee VHF, Lee AWM, Tsao SW, Tsang CM
Journal of experimental & clinical cancer research : CR 2020 Nov 26;39(1):262
Journal of experimental & clinical cancer research : CR 2020 Nov 26;39(1):262
Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis.
Zhang GL, Qian C, Zhang SZ, Tuo YH, Zeng BY, Ji YX, Wang YZ
World journal of stem cells 2020 Nov 26;12(11):1396-1409
World journal of stem cells 2020 Nov 26;12(11):1396-1409
Targeting the NCOA3-SP1-TERT axis for tumor growth in hepatocellular carcinoma.
Li W, Yan Y, Zheng Z, Zhu Q, Long Q, Sui S, Luo M, Chen M, Li Y, Hua Y, Deng W, Lai R, Li L
Cell death & disease 2020 Nov 25;11(11):1011
Cell death & disease 2020 Nov 25;11(11):1011
The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study.
Chang LC, Chiang YF, Chen HY, Huang YJ, Liu AC, Hsia SM
Biomedicines 2020 Nov 22;8(11)
Biomedicines 2020 Nov 22;8(11)
Depletion of GPSM1 enhances ovarian granulosa cell apoptosis via cAMP-PKA-CREB pathway in vitro.
Cai X, Fu H, Wang Y, Liu Q, Wang X
Journal of ovarian research 2020 Nov 21;13(1):136
Journal of ovarian research 2020 Nov 21;13(1):136
WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer.
Ertay A, Liu H, Liu D, Peng P, Hill C, Xiong H, Hancock D, Yuan X, Przewloka MR, Coldwell M, Howell M, Skipp P, Ewing RM, Downward J, Wang Y
Cell death & disease 2020 Nov 21;11(11):1001
Cell death & disease 2020 Nov 21;11(11):1001
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
Mo C, Xie S, Zhong W, Zeng T, Huang S, Lai Y, Deng G, Zhou C, Yan W, Chen Y, Huang S, Gao L, Lv Z
Free radical biology & medicine 2020 Nov 20;160:178-190
Free radical biology & medicine 2020 Nov 20;160:178-190
NEAT1 regulates microtubule stabilization via FZD3/GSK3β/P-tau pathway in SH-SY5Y cells and APP/PS1 mice.
Zhao Y, Wang Z, Mao Y, Li B, Zhu Y, Zhang S, Wang S, Jiang Y, Xu N, Xie Y, Xie W, Zhang Y
Aging 2020 Nov 18;12(22):23233-23250
Aging 2020 Nov 18;12(22):23233-23250
Tumor-associated macrophages induce PD-L1 expression in gastric cancer cells through IL-6 and TNF-ɑ signaling.
Ju X, Zhang H, Zhou Z, Chen M, Wang Q
Experimental cell research 2020 Nov 15;396(2):112315
Experimental cell research 2020 Nov 15;396(2):112315
Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose.
Zhou J, Zhang L, Zheng B, Zhang L, Qin Y, Zhang X, Yang Z, Nie Z, Yang G, Yu J, Wen J
Journal of ethnopharmacology 2020 Nov 15;262:113208
Journal of ethnopharmacology 2020 Nov 15;262:113208
Peptide DR8 suppresses epithelial-to-mesenchymal transition via the TGF-β/MAPK signaling pathway in renal fibrosis.
Deng B, Yang W, Wang D, Cheng L, Bu L, Rao J, Zhang J, Xie J, Zhang B
Life sciences 2020 Nov 15;261:118465
Life sciences 2020 Nov 15;261:118465
Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit.
Ma C, Wang X, Yang F, Zang Y, Liu J, Wang X, Xu X, Li W, Jia J, Liu Z
Molecular cancer 2020 Nov 10;19(1):157
Molecular cancer 2020 Nov 10;19(1):157
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
CB2R agonist JWH-133 attenuates chronic inflammation by restraining M1 macrophage polarization via Nrf2/HO-1 pathway in diet-induced obese mice.
Wu Q, Ma Y, Liu Y, Wang N, Zhao X, Wen D
Life sciences 2020 Nov 1;260:118424
Life sciences 2020 Nov 1;260:118424
Small molecule inhibition of cyclic GMP-AMP synthase ameliorates sepsis-induced cardiac dysfunction in mice.
Xu Q, Xiong H, Zhu W, Liu Y, Du Y
Life sciences 2020 Nov 1;260:118315
Life sciences 2020 Nov 1;260:118315
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Li X, Xiang B, Shen T, Xiao C, Dai R, He F, Lin Q
International immunopharmacology 2020 May;82:106353
International immunopharmacology 2020 May;82:106353
In vitro exposure to metformin activates human spermatozoa at therapeutically relevant concentrations.
Yang Y, Chen H, Weng S, Pan T, Chen W, Wang F, Luo T, Tang Y
Andrology 2020 May;8(3):663-670
Andrology 2020 May;8(3):663-670
XB130, regulated by miR-203, miR-219, and miR-4782-3p, mediates the proliferation and metastasis of non-small-cell lung cancer cells.
Wang Q, Yang G, Jiang Y, Luo M, Li C, Zhao Y, Xie Y, Song K, Zhou J
Molecular carcinogenesis 2020 May;59(5):557-568
Molecular carcinogenesis 2020 May;59(5):557-568
Cleavage of cyclic AMP-responsive element-binding protein H aggravates myocardial hypoxia reperfusion injury in a hepatocyte-myocardial cell co-culture system.
Jin Z, Chen Y, Weng X, Huang A, Lin S, Li H
The Journal of international medical research 2020 May;48(5):300060520904835
The Journal of international medical research 2020 May;48(5):300060520904835
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Wang Z, Cai L, Li H, Liang M, Zhang Y, Wu Q, Yang L
Journal of food biochemistry 2020 May;44(5):e13180
Journal of food biochemistry 2020 May;44(5):e13180
The Effect of Shen-Yuan-Dan Capsule on Autophagy-Related Gene Atg13 Promoter Methylation and Genomic Methylation Levels in Atherosclerotic Mice.
Lai X, Zhang Y, Li M, Shang J, Liu W, Zhou M, Liu H
Acta Cardiologica Sinica 2020 May;36(3):260-267
Acta Cardiologica Sinica 2020 May;36(3):260-267
Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.
Guo Y, Li B, Yan X, Shen X, Ma J, Liu S, Zhang D
Chemosphere 2020 May;246:125775
Chemosphere 2020 May;246:125775
Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice.
Li M, Li CM, Ye ZC, Huang J, Li Y, Lai W, Peng H, Lou TQ
Journal of cellular and molecular medicine 2020 May;24(9):5109-5121
Journal of cellular and molecular medicine 2020 May;24(9):5109-5121
Epidermal growth factor regulation by autophagy-mediated lncRNA H19 in murine intestinal tract after severe burn.
Li C, Zhuang M, Zhu B, Li Y, Zhang W, Yan H, Zhang P, Li D, Yang J, Sun Y, Chen H, Cui Q, Jin P, Sun Y
Journal of cellular and molecular medicine 2020 May;24(10):5878-5887
Journal of cellular and molecular medicine 2020 May;24(10):5878-5887
BZW2 promotes the malignant progression of colorectal cancer via activating the ERK/MAPK pathway.
Huang L, Chen S, Fan H, Ai F, Sheng W
Journal of cellular physiology 2020 May;235(5):4834-4842
Journal of cellular physiology 2020 May;235(5):4834-4842
Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway.
Wang Y, He G, Tang H, Shi Y, Zhu M, Kang X, Bian X, Lyu J, Zhou M, Yang M, Mu M, Chen W, Zhou B, Yuan C, Zhang J, Tang K
Journal of cellular physiology 2020 May;235(5):4778-4789
Journal of cellular physiology 2020 May;235(5):4778-4789
KIAA1429 promotes osteosarcoma progression by promoting stem cell properties and is regulated by miR-143-3p.
Han Q, Yang J, Yang H, Li C, Li J, Cao Y
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1172-1185
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1172-1185
Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury.
Cheng P, Liu H, Li Y, Pi P, Jiang Y, Zang S, Li X, Fu A, Ren X, Xu J, Holmgren A, Lu J
Biochemical pharmacology 2020 May;175:113873
Biochemical pharmacology 2020 May;175:113873
Regulation of the small GTPase Ran by miR-802 modulates proliferation and metastasis in colorectal cancer cells.
Wang X, Li D, Sun L, Shen G, Liu H, Guo H, Ge M, Liang J, Chen P, Zhou J, Cao T, Wang Q, Gao X, Tong M, Hu S, Nie Y, Fan D, Wang X, Zhao X, Lu Y
British journal of cancer 2020 May;122(11):1695-1706
British journal of cancer 2020 May;122(11):1695-1706
Transcription factor 7-like 2 promotes osteogenic differentiation and boron-induced bone repair via lipocalin 2.
Yin C, Jia X, Zhao Q, Zhao Z, Wang J, Zhang Y, Li Z, Sun H, Li Z
Materials science & engineering. C, Materials for biological applications 2020 May;110:110671
Materials science & engineering. C, Materials for biological applications 2020 May;110:110671
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
Deng Q, Fang Q, Xie B, Sun H, Bao Y, Zhou S
Aging 2020 May 6;12(9):8001-8015
Aging 2020 May 6;12(9):8001-8015
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
Wu N, Wu Z, Sun J, Yan M, Wang B, Du X, Liu Y
Aging 2020 May 5;12(9):7927-7944
Aging 2020 May 5;12(9):7927-7944
PIWIL4 Maintains HIV-1 Latency by Enforcing Epigenetically Suppressive Modifications on the 5' Long Terminal Repeat.
He Z, Jing S, Yang T, Chen J, Huang F, Zhang W, Peng Z, Liu B, Ma X, Wu L, Pan T, Zhang X, Li L, Cai W, Tang X, Zhang J, Zhang H
Journal of virology 2020 May 4;94(10)
Journal of virology 2020 May 4;94(10)
Fzd2 Contributes to Breast Cancer Cell Mesenchymal-Like Stemness and Drug Resistance.
Yin P, Wang W, Gao J, Bai Y, Wang Z, Na L, Sun Y, Zhao C
Oncology research 2020 May 29;28(3):273-284
Oncology research 2020 May 29;28(3):273-284
Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis.
Wang W, Zheng L, Xu L, Tu J, Gu X
Molecular medicine (Cambridge, Mass.) 2020 May 27;26(1):53
Molecular medicine (Cambridge, Mass.) 2020 May 27;26(1):53
Ibudilast enhances the clearance of SOD1 and TDP-43 aggregates through TFEB-mediated autophagy and lysosomal biogenesis: The new molecular mechanism of ibudilast and its implication for neuroprotective therapy.
Chen Y, Wang H, Ying Z, Gao Q
Biochemical and biophysical research communications 2020 May 21;526(1):231-238
Biochemical and biophysical research communications 2020 May 21;526(1):231-238
Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity.
Giovinazzo JA, Thomson RP, Khalizova N, Zager PJ, Malani N, Rodriguez-Boulan E, Raper J, Schreiner R
eLife 2020 May 19;9
eLife 2020 May 19;9
Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication.
Ma C, Xu W, Yang Q, Liu W, Xiang Q, Chen J, Zhang Q, Liu Y, Wu K, Wu J
Journal of virology 2020 May 18;94(11)
Journal of virology 2020 May 18;94(11)
MEL endomorphins act as potent inflammatory analgesics with the inhibition of activated non-neuronal cells and modulation of pro-inflammatory cytokines.
Cui JM, Zhao L, Wang ZJ, Ma MT, Wang Y, Luo KY, Wang LQ, Wei S, Zhang XH, Han CZ, Liu X, Wang R
Neuropharmacology 2020 May 15;168:107992
Neuropharmacology 2020 May 15;168:107992
ATP depletion induced cochlear hair cells death through histone deacetylation in vitro.
Fan B, Wang J, Zha D, Qiu J, Chen F
Neuroscience letters 2020 May 14;727:134918
Neuroscience letters 2020 May 14;727:134918
Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase.
Li MX, Yang Y, Zhao Q, Wu Y, Song L, Yang H, He M, Gao H, Song BL, Luo J, Rao Y
Journal of medicinal chemistry 2020 May 14;63(9):4908-4928
Journal of medicinal chemistry 2020 May 14;63(9):4908-4928
Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway.
Hou L, Fu W, Liu Y, Wang Q, Wang L, Huang Y
Investigative ophthalmology & visual science 2020 May 11;61(5):7
Investigative ophthalmology & visual science 2020 May 11;61(5):7
GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78.
Song J, Liu W, Wang J, Hao J, Wang Y, You X, Du X, Zhou Y, Ben J, Zhang X, Ye M, Wang Q
Cell death & disease 2020 May 11;11(5):352
Cell death & disease 2020 May 11;11(5):352
Silybin enhances the blood concentration of brexpiprazole in rats by downregulating expression of CYP3A4 and CYP2D6.
Yu C, Pan L, Wang G, Cai Z, Zhou Y, Zheng X, Chen C, Zhang X
Die Pharmazie 2020 May 1;75(5):198-200
Die Pharmazie 2020 May 1;75(5):198-200
The Endocannabinoid System Contributes to Memory Deficits Induced by Rapid-eye-movement Sleep Deprivation in Adolescent Mice.
Zhang J, Zhang L, Chang Y, Gu Q, Zhang J, Zhu Z, Qian Z, Wei C, Liu Z, Ren W, Han J
Neuroscience 2020 May 1;433:174-183
Neuroscience 2020 May 1;433:174-183
Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p.
Xue WL, Chen RQ, Zhang QQ, Li XH, Cao L, Li MY, Li Y, Lin G, Chen Y, Wang MJ, Zhu YC
American journal of physiology. Cell physiology 2020 May 1;318(5):C857-C869
American journal of physiology. Cell physiology 2020 May 1;318(5):C857-C869
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
Jiang L, He C, Zhang X, Chen Y, Li G
Translational cancer research 2020 Mar;9(3):1851-1860
Translational cancer research 2020 Mar;9(3):1851-1860
LncRNA FAM66C inhibits pancreatic cancer progression by sponging miR-574-3p.
Zhu J, Zhu S, Yu Q, Wu Y
Translational cancer research 2020 Mar;9(3):1806-1817
Translational cancer research 2020 Mar;9(3):1806-1817
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y
International immunopharmacology 2020 Mar;80:106123
International immunopharmacology 2020 Mar;80:106123
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from the root of Averrhoa carambola L., protects against diabetic kidney disease by inhibiting TLR4/TGFβ signaling pathway.
Zhang H, Lu S, Chen L, Huang X, Jiang L, Li Y, Liao P, Wu X, Zhou X, Qin L, Wei J, Huang R
International immunopharmacology 2020 Mar;80:106120
International immunopharmacology 2020 Mar;80:106120
LIN9 confers paclitaxel resistance in triple negative breast cancer cells by upregulating CCSAP.
Lai H, Wang R, Li S, Shi Q, Cai Z, Li Y, Liu Y
Science China. Life sciences 2020 Mar;63(3):419-428
Science China. Life sciences 2020 Mar;63(3):419-428
Role of PEPT1in the transport of cinnabar in Caco-2 cells.
Wu Q, He X, Zhou S, Shi F, Lu Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Mar;63:104747
Toxicology in vitro : an international journal published in association with BIBRA 2020 Mar;63:104747
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
Han P, Hanlon D, Arshad N, Lee JS, Tatsuno K, Robinson E, Filler R, Sobolev O, Cote C, Rivera-Molina F, Toomre D, Fahmy T, Edelson R
Science advances 2020 Mar;6(11):eaaz1580
Science advances 2020 Mar;6(11):eaaz1580
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Yan K, Wu C, Ye Y, Li L, Wang X, He W, Ren S, Xu Y
Cell proliferation 2020 Mar;53(3):e12778
Cell proliferation 2020 Mar;53(3):e12778
miR-137 and its target T-type Ca(V) 3.1 channel modulate dedifferentiation and proliferation of cerebrovascular smooth muscle cells in simulated microgravity rats by regulating calcineurin/NFAT pathway.
Zhang B, Chen L, Bai YG, Song JB, Cheng JH, Ma HZ, Ma J, Xie MJ
Cell proliferation 2020 Mar;53(3):e12774
Cell proliferation 2020 Mar;53(3):e12774
The inhibition of miR-17-5p promotes cortical neuron neurite growth via STAT3/GAP-43 pathway.
Zhang L, Wang Z, Li B, Xia Z, Wang X, Xiu Y, Zhang Z, Chen C, Song H, Li W, Yu M, Zhang M, Wang K, Guo X, Ren L, Wang T
Molecular biology reports 2020 Mar;47(3):1795-1802
Molecular biology reports 2020 Mar;47(3):1795-1802
NIT2 overexpression predicts poor prognosis in tongue squamous cell carcinoma patients.
Chen S, Wang Z, Feng C
Molecular biology reports 2020 Mar;47(3):1553-1561
Molecular biology reports 2020 Mar;47(3):1553-1561
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Malic enzyme 1 is important for uterine decidualization in response to progesterone/cAMP/PKA/HB-EGF pathway.
Yu HF, Duan CC, Yang ZQ, Wang YS, Yue ZP, Guo B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3820-3837
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3820-3837
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Gao M, Dong Z, Sun J, Liu W, Xu M, Li C, Zhu P, Yang X, Shang X, Wu Y, Liu S
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Combined tazemetostat and MAPKi enhances differentiation of papillary thyroid cancer cells harbouring BRAF(V600E) by synergistically decreasing global trimethylation of H3K27.
Fu H, Cheng L, Sa R, Jin Y, Chen L
Journal of cellular and molecular medicine 2020 Mar;24(6):3336-3345
Journal of cellular and molecular medicine 2020 Mar;24(6):3336-3345
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Ren J, Zhang L, Zhang J, Zhang W, Cao Y, Xu Z, Cui H, Kang Y, Xue P
Biomaterials 2020 Mar;234:119771
Biomaterials 2020 Mar;234:119771
Overexpressed DAAM1 correlates with metastasis and predicts poor prognosis in breast cancer.
Mei J, Xu B, Hao L, Xiao Z, Liu Y, Yan T, Zhu Y
Pathology, research and practice 2020 Mar;216(3):152736
Pathology, research and practice 2020 Mar;216(3):152736
ROS/p53/miR‑335‑5p/Sp1 axis modulates the migration and epithelial to mesenchymal transition of JEG‑3 cells.
Lu W, Ma YY, Shao QQ, Liang J, Qi TT, Huang Y, Wang QJ
Molecular medicine reports 2020 Mar;21(3):1208-1216
Molecular medicine reports 2020 Mar;21(3):1208-1216
Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase-3β-mediated activation of autophagy.
Gao J, Long L, Xu F, Feng L, Liu Y, Shi J, Gong Q
British journal of pharmacology 2020 Mar;177(6):1434-1452
British journal of pharmacology 2020 Mar;177(6):1434-1452
UDP-Glucuronosyltransferase (UGT)-mediated attenuations of cytochrome P450 3A4 activity: UGT isoform-dependent mechanism of suppression.
Miyauchi Y, Tanaka Y, Nagata K, Yamazoe Y, Mackenzie PI, Yamada H, Ishii Y
British journal of pharmacology 2020 Mar;177(5):1077-1089
British journal of pharmacology 2020 Mar;177(5):1077-1089
Metastatic Melanoma Cells Rely on Sestrin2 to Acquire Anoikis Resistance via Detoxifying Intracellular ROS.
Zhu G, Xu P, Guo S, Yi X, Wang H, Yang Y, Liu L, Shi Q, Gao T, Li C
The Journal of investigative dermatology 2020 Mar;140(3):666-675.e2
The Journal of investigative dermatology 2020 Mar;140(3):666-675.e2
Ganoderal A effectively induces osteogenic differentiation of human amniotic mesenchymal stem cells via cross-talk between Wnt/β-catenin and BMP/SMAD signaling pathways.
Wang YQ, Wang NX, Luo Y, Yu CY, Xiao JH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109807
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109807
CADM1 inhibits ovarian cancer cell proliferation and migration by potentially regulating the PI3K/Akt/mTOR pathway.
Si X, Xu F, Xu F, Wei M, Ge Y, Chenge S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109717
LncRNA-cCSC1 modulates cancer stem cell properties in colorectal cancer via activation of the Hedgehog signaling pathway.
Zhou H, Xiong Y, Peng L, Wang R, Zhang H, Fu Z
Journal of cellular biochemistry 2020 Mar;121(3):2510-2524
Journal of cellular biochemistry 2020 Mar;121(3):2510-2524
M-phase phosphoprotein 8 promotes gastric cancer growth and metastasis via p53/Bcl-2 and EMT-related signaling pathways.
Wang Y, Xiao H, Wang C, Wu H, He H, Yao C, Cui J, Li W
Journal of cellular biochemistry 2020 Mar;121(3):2330-2342
Journal of cellular biochemistry 2020 Mar;121(3):2330-2342
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, Xu Z, Wang X, Wang Y, Zhu Y, Wang W
Archives of oral biology 2020 Mar;111:104646
Archives of oral biology 2020 Mar;111:104646
RIP1/RIP3/MLKL mediates dopaminergic neuron necroptosis in a mouse model of Parkinson disease.
Lin QS, Chen P, Wang WX, Lin CC, Zhou Y, Yu LH, Lin YX, Xu YF, Kang DZ
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):503-511
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):503-511
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF(β-TRCP)-Mediated Degradation of NRF2 in Pancreatic Cancer.
Yang Q, Li K, Huang X, Zhao C, Mei Y, Li X, Jiao L, Yang H
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
LINC00680 and TTN-AS1 Stabilized by EIF4A3 Promoted Malignant Biological Behaviors of Glioblastoma Cells.
Tang W, Wang D, Shao L, Liu X, Zheng J, Xue Y, Ruan X, Yang C, Liu L, Ma J, Li Z, Liu Y
Molecular therapy. Nucleic acids 2020 Mar 6;19:905-921
Molecular therapy. Nucleic acids 2020 Mar 6;19:905-921
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
Zhang P, Yi L, Qu S, Dai J, Li X, Liu B, Li H, Ai K, Zheng P, Qiu S, Li Y, Wang Y, Xiang X, Chai X, Dong Z, Zhang D
Molecular therapy. Nucleic acids 2020 Mar 6;19:1027-1042
Molecular therapy. Nucleic acids 2020 Mar 6;19:1027-1042
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Liu Q, Yang C, Wang S, Shi D, Wei C, Song J, Lin X, Dou R, Bai J, Xiang Z, Huang S, Liu K, Xiong B
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
2-phenylethynesulfonamide inhibits growth of oral squamous cell carcinoma cells by blocking the function of heat shock protein 70.
Jiang L, Xiao J
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.
Cai R, Wang P, Zhao X, Lu X, Deng R, Wang X, Su Z, Hong C, Lin J
Journal of translational medicine 2020 Mar 26;18(1):139
Journal of translational medicine 2020 Mar 26;18(1):139
Exosomes derived from human umbilical cord mesenchymal stem cells inhibit vein graft intimal hyperplasia and accelerate reendothelialization by enhancing endothelial function.
Qu Q, Pang Y, Zhang C, Liu L, Bi Y
Stem cell research & therapy 2020 Mar 23;11(1):133
Stem cell research & therapy 2020 Mar 23;11(1):133
Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway.
Ma L, Sun Y, Li D, Li H, Jin X, Ren D
Aging 2020 Mar 22;12(6):5336-5351
Aging 2020 Mar 22;12(6):5336-5351
Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation.
Deng L, Li H, Su X, Zhang Y, Xu H, Fan L, Fan J, Han Q, Bai X, Zhao RC
Cell death & disease 2020 Mar 2;11(3):158
Cell death & disease 2020 Mar 2;11(3):158
Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.
Gonatopoulos-Pournatzis T, Niibori R, Salter EW, Weatheritt RJ, Tsang B, Farhangmehr S, Liang X, Braunschweig U, Roth J, Zhang S, Henderson T, Sharma E, Quesnel-Vallières M, Permanyer J, Maier S, Georgiou J, Irimia M, Sonenberg N, Forman-Kay JD, Gingras AC, Collingridge GL, Woodin MA, Cordes SP, Blencowe BJ
Molecular cell 2020 Mar 19;77(6):1176-1192.e16
Molecular cell 2020 Mar 19;77(6):1176-1192.e16
Impacts of Aerobic Exercise on Depression-Like Behaviors in Chronic Unpredictable Mild Stress Mice and Related Factors in the AMPK/PGC-1α Pathway.
Luo J, Tang C, Chen X, Ren Z, Qu H, Chen R, Tong Z
International journal of environmental research and public health 2020 Mar 19;17(6)
International journal of environmental research and public health 2020 Mar 19;17(6)
Using ESTIMATE algorithm to establish an 8-mRNA signature prognosis prediction system and identify immunocyte infiltration-related genes in Pancreatic adenocarcinoma.
Meng Z, Ren D, Zhang K, Zhao J, Jin X, Wu H
Aging 2020 Mar 17;12(6):5048-5070
Aging 2020 Mar 17;12(6):5048-5070
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Gao W, Guo X, Wang Y, Jian D, Li M
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.
Shi J, Ren M, She X, Zhang Z, Zhao Y, Han Y, Lu D, Lyu L
Biochemical and biophysical research communications 2020 Mar 12;523(3):632-638
Biochemical and biophysical research communications 2020 Mar 12;523(3):632-638
SOX12 promotes the growth of multiple myeloma cells by enhancing Wnt/β-catenin signaling.
Gao Y, Li L, Hou L, Niu B, Ru X, Zhang D
Experimental cell research 2020 Mar 1;388(1):111814
Experimental cell research 2020 Mar 1;388(1):111814
Carbon disulfide induced decidualization disorder in the mice uterus at the window of implantation.
Huang F, Wu Y, Zhang D, Liu X, Wang Z
Ecotoxicology and environmental safety 2020 Mar 1;190:110069
Ecotoxicology and environmental safety 2020 Mar 1;190:110069
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Yu M, Zeng M, Pan Z, Wu F, Guo L, He G
European journal of medicinal chemistry 2020 Mar 1;189:112076
European journal of medicinal chemistry 2020 Mar 1;189:112076
The immunomodulatory role of irisin on osteogenesis via AMPK-mediated macrophage polarization.
Ye W, Wang J, Lin D, Ding Z
International journal of biological macromolecules 2020 Mar 1;146:25-35
International journal of biological macromolecules 2020 Mar 1;146:25-35
Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage.
Lin QS, Wang WX, Lin YX, Lin ZY, Yu LH, Kang Y, Kang DZ
Journal of neurosurgery 2020 Mar 1;132(3):777-787
Journal of neurosurgery 2020 Mar 1;132(3):777-787
1,25-Dihydroxyvitamin D attenuates diabetic cardiac autophagy and damage by vitamin D receptor-mediated suppression of FoxO1 translocation.
Guo X, Lin H, Liu J, Wang D, Li D, Jiang C, Tang Y, Wang J, Zhang T, Li Y, Yao P
The Journal of nutritional biochemistry 2020 Jun;80:108380
The Journal of nutritional biochemistry 2020 Jun;80:108380
Mitochondrial encephalopathy Due to a Novel Pathogenic Mitochondrial tRNA(Gln) m.4349C>T Variant.
Ji K, Wang W, Lin Y, Xu X, Liu F, Wang D, Zhao Y, Yan C
Annals of clinical and translational neurology 2020 Jun;7(6):980-991
Annals of clinical and translational neurology 2020 Jun;7(6):980-991
Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling.
Hu X, Zhang L, Li Y, Ma X, Dai W, Gao X, Rao X, Fu G, Wang R, Pan M, Guo Q, Xu X, Zhou Y, Gao J, Zhang Z, Cai S, Peng J, Hua G
EBioMedicine 2020 Jun;56:102800
EBioMedicine 2020 Jun;56:102800
Oxidative stress induced pyroptosis leads to osteogenic dysfunction of MG63 cells.
Liu S, Du J, Li D, Yang P, Kou Y, Li C, Zhou Q, Lu Y, Hasegawa T, Li M
Journal of molecular histology 2020 Jun;51(3):221-232
Journal of molecular histology 2020 Jun;51(3):221-232
Yu Gan Long Ameliorates Hepatic Fibrosis by Inhibiting PI3K/AKT, Ras/ERK and JAK1/STAT3 Signaling Pathways in CCl(4)-induced Liver Fibrosis Rats.
Li HG, You PT, Xia Y, Cai Y, Tu YJ, Wang MH, Song WC, Quan TM, Ren HY, Liu YW, Dan HX, Xu SQ
Current medical science 2020 Jun;40(3):539-547
Current medical science 2020 Jun;40(3):539-547
Recombinant HvRNASET2 protein induces marked connective tissue remodelling in the invertebrate model Hirudo verbana.
Baranzini N, Weiss-Gayet M, Chazaud B, Monti L, de Eguileor M, Tettamanti G, Acquati F, Grimaldi A
Cell and tissue research 2020 Jun;380(3):565-579
Cell and tissue research 2020 Jun;380(3):565-579
Genetic deletion of microRNA biogenesis in muscle cells reveals a hierarchical non-clustered network that controls focal adhesion signaling during muscle regeneration.
Luca E, Turcekova K, Hartung A, Mathes S, Rehrauer H, Krützfeldt J
Molecular metabolism 2020 Jun;36:100967
Molecular metabolism 2020 Jun;36:100967
CircDDX17 acts as a competing endogenous RNA for miR-605 in breast cancer progression.
Peng HH, Wen YG
European review for medical and pharmacological sciences 2020 Jun;24(12):6794-6801
European review for medical and pharmacological sciences 2020 Jun;24(12):6794-6801
Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
Liu H, Chen C, Ma D, Li Y, Yin Q, Li Q, Xiang C
Journal of cellular and molecular medicine 2020 Jun;24(11):6308-6323
Journal of cellular and molecular medicine 2020 Jun;24(11):6308-6323
Effects of Secreted frizzled-related protein 1 on inhibiting cardiac remodeling.
Wang H, Liu Y, Liang X, Yang G, Liu Y, Li F, Guo YT, Wang HJ, Liu HB, Chen L
European review for medical and pharmacological sciences 2020 Jun;24(11):6270-6278
European review for medical and pharmacological sciences 2020 Jun;24(11):6270-6278
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Li H, Liang M, Wang Z, Zhang Y, Wu Q, Yang L
Journal of medicinal food 2020 Jun;23(6):565-574
Journal of medicinal food 2020 Jun;23(6):565-574
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
Chen GH, Zhang XL, Chen H, Lin H, Wu HJ, Lin H, Huang GZ
The journal of gene medicine 2020 Jun;22(6):e3174
The journal of gene medicine 2020 Jun;22(6):e3174
GRIM-19 deficiency promotes clear cell renal cell carcinoma progression and is associated with high TNM stage and Fuhrman grade.
Yan N, Feng X, Jiang S, Sun W, Sun MZ, Liu S
Oncology letters 2020 Jun;19(6):4115-4121
Oncology letters 2020 Jun;19(6):4115-4121
Seminal Plasma Proteome as an Indicator of Sperm Dysfunction and Low Sperm Motility in Chickens.
Li Y, Sun Y, Ni A, Shi L, Wang P, Isa AM, Ge P, Jiang L, Fan J, Ma H, Yang G, Chen J
Molecular & cellular proteomics : MCP 2020 Jun;19(6):1035-1046
Molecular & cellular proteomics : MCP 2020 Jun;19(6):1035-1046
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
Wu J, He J, Tian X, Luo Y, Zhong J, Zhang H, Li H, Cen B, Jiang T, Sun X
Journal of neurochemistry 2020 Jun;153(6):710-726
Journal of neurochemistry 2020 Jun;153(6):710-726
Homer1a protects against neuronal injury via PI3K/AKT/mTOR signaling pathway.
Wang Y, Zhao M, Shang L, Zhang Y, Huang C, He Z, Luo M, Wu B, Song P, Wang M, Duan F
The International journal of neuroscience 2020 Jun;130(6):621-630
The International journal of neuroscience 2020 Jun;130(6):621-630
Intra-Amniotic Delivery of CRMP4 siRNA Improves Mesenchymal Stem Cell Therapy in a Rat Spina Bifida Model.
Wei X, Cao S, Ma W, Zhang C, Gu H, Liu D, Luo W, Bai Y, Wang W, Yuan Z
Molecular therapy. Nucleic acids 2020 Jun 5;20:502-517
Molecular therapy. Nucleic acids 2020 Jun 5;20:502-517
Hfm1 participates in Golgi-associated spindle assembly and division in mouse oocyte meiosis.
Wang H, Zhong C, Yang R, Yin Y, Tan R, Gao L, Gao C, Cui Y, Pu D, Wu J
Cell death & disease 2020 Jun 30;11(6):490
Cell death & disease 2020 Jun 30;11(6):490
Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age.
Bilinska K, Jakubowska P, Von Bartheld CS, Butowt R
ACS chemical neuroscience 2020 Jun 3;11(11):1555-1562
ACS chemical neuroscience 2020 Jun 3;11(11):1555-1562
Proteomics analysis of tumor exosomes reveals vital pathways of Jinfukang inhibiting circulating tumor cells metastasis in lung cancer.
Que ZJ, Luo B, Wang CT, Qian FF, Jiang Y, Li Y, Han XH, Li HG, Liu JX, Tian JH
Journal of ethnopharmacology 2020 Jun 28;256:112802
Journal of ethnopharmacology 2020 Jun 28;256:112802
Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells.
You R, Zhou W, Li Y, Zhang Y, Huang S, Jia Z, Zhang A
Clinical science (London, England : 1979) 2020 Jun 26;134(12):1357-1376
Clinical science (London, England : 1979) 2020 Jun 26;134(12):1357-1376
PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target.
Wang J, Wang L, Chen S, Peng H, Xiao L, E Du, Liu Y, Lin D, Wang Y, Xu Y, Yang K
Gene 2020 Jun 20;744:144608
Gene 2020 Jun 20;744:144608
Tollip coordinates Parkin-dependent trafficking of mitochondrial-derived vesicles.
Ryan TA, Phillips EO, Collier CL, Jb Robinson A, Routledge D, Wood RE, Assar EA, Tumbarello DA
The EMBO journal 2020 Jun 2;39(11):e102539
The EMBO journal 2020 Jun 2;39(11):e102539
Different effects of total flavonoids from Arachniodes exilis on human umbilical cord mesenchymal stem cells in vitro.
Yu W, Hu W, Ke X, Zhou X, Yin C, Yin M
Medicine 2020 Jun 19;99(25):e20628
Medicine 2020 Jun 19;99(25):e20628
Discovery of Isoplumbagin as a Novel NQO1 Substrate and Anti-Cancer Quinone.
Tsao YC, Chang YJ, Wang CH, Chen L
International journal of molecular sciences 2020 Jun 19;21(12)
International journal of molecular sciences 2020 Jun 19;21(12)
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
Cui Y, Li F, Xie Q, Zhao S, Guo T, Guo P, Hu S, Hao J, Tian C, Yu W, Li Z, Fang L, Zhao L, Chen M, Wu T, Gu C
Cell death & disease 2020 Jun 19;11(6):476
Cell death & disease 2020 Jun 19;11(6):476
The miR-532-3p/Chrdl1 axis regulates the proliferation and migration of amniotic fluid-derived mesenchymal stromal cells.
Huang J, Wei X, Ma W, Yuan Z
Biochemical and biophysical research communications 2020 Jun 18;527(1):187-193
Biochemical and biophysical research communications 2020 Jun 18;527(1):187-193
Bacterial Pigment Prodigiosin Demonstrates a Unique Antiherpesvirus Activity That Is Mediated through Inhibition of Prosurvival Signal Transducers.
Suryawanshi RK, Koujah L, Patil CD, Ames JM, Agelidis A, Yadavalli T, Patil SV, Shukla D
Journal of virology 2020 Jun 16;94(13)
Journal of virology 2020 Jun 16;94(13)
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
Yadav VK, Huang YJ, George TA, Wei PL, Sumitra MR, Ho CL, Chang TH, Wu ATH, Huang HS
Cancers 2020 Jun 16;12(6)
Cancers 2020 Jun 16;12(6)
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Toxicology and applied pharmacology 2020 Jun 15;397:115014
PM(2.5)-inducible long non-coding RNA (NONHSAT247851.1) is a positive regulator of inflammation through its interaction with raf-1 in HUVECs.
Zhou C, Tan Y, Wang Y, Liao F, Wang Q, Li J, Peng S, Peng X, Zou Y
Ecotoxicology and environmental safety 2020 Jun 15;196:110476
Ecotoxicology and environmental safety 2020 Jun 15;196:110476
Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling.
Dai H, Li M, Yang W, Sun X, Wang P, Wang X, Su J, Wang X, Hu X, Zhao M
Aging 2020 Jun 12;12(12):11717-11731
Aging 2020 Jun 12;12(12):11717-11731
Lim Kinase1 regulates seizure activity via modulating actin dynamics.
Jiang Q, Tang G, Fu J, Yang J, Xu T, Tan CH, Wang Y, Chen YM
Neuroscience letters 2020 Jun 11;729:134936
Neuroscience letters 2020 Jun 11;729:134936
2-((4-Arylpiperazin-1-yl)methyl)benzonitrile Derivatives as Orally Available Inhibitors of Hepatitis C Virus with a Novel Mechanism of Action.
Jiang X, Tan J, Wang Y, Chen J, Li J, Jiang Z, Quan Y, Jin J, Li Y, Cen S, Li Y, Peng Z, Li Z
Journal of medicinal chemistry 2020 Jun 11;63(11):5972-5989
Journal of medicinal chemistry 2020 Jun 11;63(11):5972-5989
Peripheral FGFR1 Regulates Myofascial Pain in Rats via the PI3K/AKT Pathway.
Zhang M, Jin F, Zhu Y, Qi F
Neuroscience 2020 Jun 1;436:1-10
Neuroscience 2020 Jun 1;436:1-10
Nogo-B fosters HCC progression by enhancing Yap/Taz-mediated tumor-associated macrophages M2 polarization.
Zhao X, Wang X, You Y, Wen D, Feng Z, Zhou Y, Que K, Gong J, Liu Z
Experimental cell research 2020 Jun 1;391(1):111979
Experimental cell research 2020 Jun 1;391(1):111979
Sestrin2 overexpression alleviates hydrogen peroxide-induced apoptosis and oxidative stress in retinal ganglion cells by enhancing Nrf2 activation via Keap1 downregulation.
Fan Y, Xing Y, Xiong L, Wang J
Chemico-biological interactions 2020 Jun 1;324:109086
Chemico-biological interactions 2020 Jun 1;324:109086
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, Hu Y, Jiang Y, Ma Y, Wang H, Bennett EJ, Fu G, Hui E
The Journal of cell biology 2020 Jun 1;219(6)
The Journal of cell biology 2020 Jun 1;219(6)
Calcitriol decreases live Porphyromonas gingivalis internalized into epithelial cells and monocytes by promoting autophagy.
Hu X, Niu L, Ma C, Huang Y, Yang X, Shi Y, Pan C, Liu J, Wang H, Li Q, Geng F, Tang X
Journal of periodontology 2020 Jul;91(7):956-966
Journal of periodontology 2020 Jul;91(7):956-966
Long Noncoding RNA LNC_000898 Alleviates Cardiomyocyte Apoptosis and Promotes Cardiac Repair After Myocardial Infarction Through Modulating the miR-375/PDK1 Axis.
Yan M, Liu Q, Jiang Y, Wang B, Ji Y, Liu H, Xie Y
Journal of cardiovascular pharmacology 2020 Jul;76(1):77-85
Journal of cardiovascular pharmacology 2020 Jul;76(1):77-85
LRIG3 represses cell motility by inhibiting slug via inactivating ERK signaling in human colorectal cancer.
Zeng K, Chen X, Xu M, Liu X, Li C, Xu X, Pan B, Qin J, He B, Pan Y, Huiling S, Xu T, Wang S
IUBMB life 2020 Jul;72(7):1393-1403
IUBMB life 2020 Jul;72(7):1393-1403
Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.
Chen DQ, Wang YN, Vaziri ND, Chen L, Hu HH, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153232
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153232
The tumor suppressor NOR1 suppresses cell growth, invasiveness, and tumorigenicity in glioma.
Cai J, Liu C, Yi M, Tan Y, Chen S, Ren N, Cheng H, Li X, Xiong W, Li G, Wu M, Wang W, Xiang B
Neoplasma 2020 Jul;67(4):851-860
Neoplasma 2020 Jul;67(4):851-860
G6PD facilitates clear cell renal cell carcinoma invasion by enhancing MMP2 expression through ROS‑MAPK axis pathway.
Zhang Q, Han Q, Yang Z, Ni Y, Agbana YL, Bai H, Yi Z, Yi X, Kuang Y, Zhu Y
International journal of oncology 2020 Jul;57(1):197-212
International journal of oncology 2020 Jul;57(1):197-212
Maternal Treadmill Exercise Reduces the Neurotoxicity of Prenatal Sevoflurane Exposure in Rats via Activation of p300 Histone Acetyltransferase.
Wu Z, Zhang Y, Yang X, Zhao P
Neurochemical research 2020 Jul;45(7):1626-1635
Neurochemical research 2020 Jul;45(7):1626-1635
Transplantation of IFN-γ Primed hUCMSCs Significantly Improved Outcomes of Experimental Autoimmune Encephalomyelitis in a Mouse Model.
Zhou X, Liu X, Liu L, Han C, Xie Z, Liu X, Xu Y, Li F, Bi J, Zheng C
Neurochemical research 2020 Jul;45(7):1510-1517
Neurochemical research 2020 Jul;45(7):1510-1517
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, Wu D, Ji X
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
Bidirectional interaction of lncRNA AFAP1-AS1 and CRKL accelerates the proliferative and metastatic abilities of hepatocarcinoma cells.
Abdul S, Majid A, Wang J, Liu Q, Sun MZ, Liu S
Journal of advanced research 2020 Jul;24:121-130
Journal of advanced research 2020 Jul;24:121-130
MicroRNA-214-3p enhances erastin-induced ferroptosis by targeting ATF4 in hepatoma cells.
Bai T, Liang R, Zhu R, Wang W, Zhou L, Sun Y
Journal of cellular physiology 2020 Jul;235(7-8):5637-5648
Journal of cellular physiology 2020 Jul;235(7-8):5637-5648
miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1.
Chen Y, Liu C, Xie B, Chen S, Zhuang Y, Zhang S
Molecular medicine reports 2020 Jul;22(1):543-550
Molecular medicine reports 2020 Jul;22(1):543-550
Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA‑MB‑231 cells.
Huang Y, Huang H, Wang S, Chen F, Zheng G
Molecular medicine reports 2020 Jul;22(1):43-50
Molecular medicine reports 2020 Jul;22(1):43-50
Partial silencing of fucosyltransferase 8 gene expression inhibits proliferation of Ishikawa cells, a cell line of endometrial cancer.
Shimoyama H, Shibata TK, Ito M, Oda T, Itoh T, Mukai M, Matsuya-Ogawa M, Adachi M, Murakami H, Nakayama T, Sugihara K, Itoh H, Suzuki T, Kanayama N
Biochemistry and biophysics reports 2020 Jul;22:100740
Biochemistry and biophysics reports 2020 Jul;22:100740
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Wei H, Zhang HL, Wang XC, Xie JZ, An DD, Wan L, Wang JZ, Zeng Y, Shu XJ, Westermarck J, Lu YM, Ohlmeyer M, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
MKP1 in the medial prefrontal cortex modulates chronic neuropathic pain via regulation of p38 and JNK1/2.
Qian Y, Wang Z, Zhou S, Zhao W, Yin C, Cao J, Wang Z, Li Y
The International journal of neuroscience 2020 Jul;130(7):643-652
The International journal of neuroscience 2020 Jul;130(7):643-652
Upregulation of miR-92a-2-5p potentially contribute to anorectal malformations by inhibiting proliferation and enhancing apoptosis via PRKCA/β-catenin.
Long CY, Xiao YX, Li SY, Tang XB, Yuan ZW, Bai YZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110117
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110117
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506
Cell death & disease 2020 Jul 6;11(7):506
Oocytes and hypoxanthine orchestrate the G2-M switch mechanism in ovarian granulosa cells.
Li C, Meng X, Liu S, Li W, Zhang X, Zhou J, Yao W, Dong C, Liu Z, Zhou J, Li J, Tao J, Wu W, Shen M, Liu H
Development (Cambridge, England) 2020 Jul 3;147(13)
Development (Cambridge, England) 2020 Jul 3;147(13)
hUMSC transplantation restores ovarian function in POI rats by inhibiting autophagy of theca-interstitial cells via the AMPK/mTOR signaling pathway.
Lu X, Bao H, Cui L, Zhu W, Zhang L, Xu Z, Man X, Chu Y, Fu Q, Zhang H
Stem cell research & therapy 2020 Jul 3;11(1):268
Stem cell research & therapy 2020 Jul 3;11(1):268
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
Bajc Česnik A, Motaln H, Rogelj B
Cells 2020 Jul 28;9(8)
Cells 2020 Jul 28;9(8)
Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p- TGF-β1 axis.
Shang A, Gu C, Wang W, Wang X, Sun J, Zeng B, Chen C, Chang W, Ping Y, Ji P, Wu J, Quan W, Yao Y, Zhou Y, Sun Z, Li D
Molecular cancer 2020 Jul 27;19(1):117
Molecular cancer 2020 Jul 27;19(1):117
Clinically relevant high levels of human C-reactive protein induces endothelial dysfunction and hypertension by inhibiting the AMPK-eNOS axis.
Cheng L, Wang L, Guo M, He J, Deng Y, Liu J, Wei Y, Wang C, Zhou J, Ma L, Song Q, Yuan Z, Wu Y
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1805-1819
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1805-1819
Long noncoding RNA NEAT1 sponges miR-129 to modulate renal fibrosis by regulation of collagen type I.
Li C, Liu YF, Huang C, Chen YX, Xu CY, Chen Y
American journal of physiology. Renal physiology 2020 Jul 1;319(1):F93-F105
American journal of physiology. Renal physiology 2020 Jul 1;319(1):F93-F105
Dietary Glucose Increases Glucose Absorption and Lipid Deposition via SGLT1/2 Signaling and Acetylated ChREBP in the Intestine and Isolated Intestinal Epithelial Cells of Yellow Catfish.
Zhao T, Yang SB, Chen GH, Xu YH, Xu YC, Luo Z
The Journal of nutrition 2020 Jul 1;150(7):1790-1798
The Journal of nutrition 2020 Jul 1;150(7):1790-1798
Inhibition of microRNA-92a ameliorates lipopolysaccharide-induced endothelial barrier dysfunction by targeting ITGA5 through the PI3K/Akt signaling pathway in human pulmonary microvascular endothelial cells.
Xu F, Zhou F
International immunopharmacology 2020 Jan;78:106060
International immunopharmacology 2020 Jan;78:106060
LncRNA NEAT1 promotes docetaxel resistance in prostate cancer by regulating ACSL4 via sponging miR-34a-5p and miR-204-5p.
Jiang X, Guo S, Zhang Y, Zhao Y, Li X, Jia Y, Xu Y, Ma B
Cellular signalling 2020 Jan;65:109422
Cellular signalling 2020 Jan;65:109422
Baicalein inhibits the growth of oral squamous cell carcinoma cells by downregulating the expression of transcription factor Sp1.
Gao Z, Zhang Y, Zhou H, Lv J
International journal of oncology 2020 Jan;56(1):273-282
International journal of oncology 2020 Jan;56(1):273-282
Bladder cancer cell‑secreted exosomal miR‑21 activates the PI3K/AKT pathway in macrophages to promote cancer progression.
Lin F, Yin HB, Li XY, Zhu GM, He WY, Gou X
International journal of oncology 2020 Jan;56(1):151-164
International journal of oncology 2020 Jan;56(1):151-164
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, He G, Han B
Cell proliferation 2020 Jan;53(1):e12701
Cell proliferation 2020 Jan;53(1):e12701
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Jiang ZH, Tang YZ, Song HN, Yang M, Li B, Ni CL
International journal of molecular medicine 2020 Jan;45(1):45-52
International journal of molecular medicine 2020 Jan;45(1):45-52
Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells.
Zhang ZL, Wang NN, Ma QL, Chen Y, Yao L, Zhang L, Li QS, Shi MH, Wang HF, Ying Z
Acta pharmacologica Sinica 2020 Jan;41(1):93-100
Acta pharmacologica Sinica 2020 Jan;41(1):93-100
Fusobacterium nucleatum Caused DNA Damage and Promoted Cell Proliferation by the Ku70/p53 Pathway in Oral Cancer Cells.
Geng F, Zhang Y, Lu Z, Zhang S, Pan Y
DNA and cell biology 2020 Jan;39(1):144-151
DNA and cell biology 2020 Jan;39(1):144-151
Auxiliary subunits control biophysical properties and response to compound NS5806 of the Kv4 potassium channel complex.
Zhang H, Zhang H, Wang C, Wang Y, Zou R, Shi C, Guan B, Gamper N, Xu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):807-821
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):807-821
MiR-490-5p functions as tumor suppressor in childhood neuroblastoma by targeting MYEOV.
Wang J, Zhang X, Yao H, Le Y, Zhou W, Li J, Lu L, Chen M, Li X
Human cell 2020 Jan;33(1):261-271
Human cell 2020 Jan;33(1):261-271
LncRNA MYCNOS facilitates proliferation and invasion in hepatocellular carcinoma by regulating miR-340.
Yu J, Ou Z, Lei Y, Chen L, Su Q, Zhang K
Human cell 2020 Jan;33(1):148-158
Human cell 2020 Jan;33(1):148-158
Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.
Xie M, Yin Y, Chen L, Yin A, Liu Y, Liu Y, Dong L, Lai Q, Zhou J, Zhang L, Xu M, Chen Z, Zuo D
The FEBS journal 2020 Jan;287(2):310-324
The FEBS journal 2020 Jan;287(2):310-324
Knockdown of SGK1 alleviates the IL-1β-induced chondrocyte anabolic and catabolic imbalance by activating FoxO1-mediated autophagy in human chondrocytes.
Huang W, Cheng C, Shan WS, Ding ZF, Liu FE, Lu W, He W, Xu JG, Yin ZS
The FEBS journal 2020 Jan;287(1):94-107
The FEBS journal 2020 Jan;287(1):94-107
Liraglutide Lowers Body Weight Set Point in DIO Rats and its Relationship with Hypothalamic Microglia Activation.
Liao T, Zhang SL, Yuan X, Mo WQ, Wei F, Zhao SN, Yang W, Liu H, Rong X
Obesity (Silver Spring, Md.) 2020 Jan;28(1):122-131
Obesity (Silver Spring, Md.) 2020 Jan;28(1):122-131
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Deng J, Xu T, Yang J, Zhang KM, Li Q, Yu XY, Li R, Fu J, Jiang Q, Ma JX, Chen YM
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
Neural stem cell-derived exosomes facilitate spinal cord functional recovery after injury by promoting angiogenesis.
Zhong D, Cao Y, Li CJ, Li M, Rong ZJ, Jiang L, Guo Z, Lu HB, Hu JZ
Experimental biology and medicine (Maywood, N.J.) 2020 Jan;245(1):54-65
Experimental biology and medicine (Maywood, N.J.) 2020 Jan;245(1):54-65
Circular RNA USP1 regulates the permeability of blood-tumour barrier via miR-194-5p/FLI1 axis.
Gao Y, Wu P, Ma Y, Xue Y, Liu Y, Zheng J, Liu X, He Q, Ma J, Liu L, Wang P
Journal of cellular and molecular medicine 2020 Jan;24(1):342-355
Journal of cellular and molecular medicine 2020 Jan;24(1):342-355
Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer.
Wei W, Liu C
Molecular medicine reports 2020 Jan;21(1):267-281
Molecular medicine reports 2020 Jan;21(1):267-281
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.
Kaddour H, Lyu Y, Welch JL, Paromov V, Mandape SN, Sakhare SS, Pandhare J, Stapleton JT, Pratap S, Dash C, Okeoma CM
Molecular & cellular proteomics : MCP 2020 Jan;19(1):78-100
Molecular & cellular proteomics : MCP 2020 Jan;19(1):78-100
Histone deacetylase inhibitors differentially regulate c-Myc expression in retinoblastoma cells.
Yu N, Chen P, Wang Q, Liang M, Qiu J, Zhou P, Yang M, Yang P, Wu Y, Han X, Ge J, Zhuang J, Yu K
Oncology letters 2020 Jan;19(1):460-468
Oncology letters 2020 Jan;19(1):460-468
Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition.
Ren L, Mo W, Wang L, Wang X
Experimental and therapeutic medicine 2020 Jan;19(1):367-374
Experimental and therapeutic medicine 2020 Jan;19(1):367-374
Resveratrol alleviates obesity-associated podocyte injury in ovariectomized obese rats.
Li B, Xiao X, Miao Y, Guo L, Zhen J, Li X, Jiang B, Hu Z
Experimental and therapeutic medicine 2020 Jan;19(1):123-130
Experimental and therapeutic medicine 2020 Jan;19(1):123-130
Downregulation of HMGB1 by miR-103a-3p Promotes Cell Proliferation, Alleviates Apoptosis and in Flammation in a Cell Model of Osteoarthritis.
Cheng M, Wang Y
Iranian journal of biotechnology 2020 Jan;18(1):e2255
Iranian journal of biotechnology 2020 Jan;18(1):e2255
RNA binding protein FXR1-miR301a-3p axis contributes to p21WAF1 degradation in oral cancer.
Majumder M, Palanisamy V
PLoS genetics 2020 Jan;16(1):e1008580
PLoS genetics 2020 Jan;16(1):e1008580
Human umbilical cord blood mononuclear cells protect against renal tubulointerstitial fibrosis in cisplatin-treated rats.
Li XW, Feng LX, Zhu XJ, Liu Q, Wang HS, Wu X, Yan P, Duan XJ, Xiao YQ, Cheng W, Peng JC, Zhao F, Deng YH, Duan SB
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109310
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109310
Inhibition of Peripheral ERK Signaling Ameliorates Persistent Muscle Pain Around Trigger Points in Rats.
Zhu YC, Jin FH, Zhang MY, Qi F
Cell transplantation 2020 Jan-Dec;29:963689720960190
Cell transplantation 2020 Jan-Dec;29:963689720960190
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Duan TL, Jiao H, He GJ, Yan YB
Cells 2020 Jan 9;9(1)
Cells 2020 Jan 9;9(1)
Critical role of IL-1β in the pathogenesis of Agrocybe aegerita galectin-induced liver injury through recruiting T cell to liver.
Yu W, Lan X, Cai J, Wang X, Liu X, Ye X, Yang Q, Su Y, Xu B, Chen T, Li L, Sun H
Biochemical and biophysical research communications 2020 Jan 8;521(2):449-456
Biochemical and biophysical research communications 2020 Jan 8;521(2):449-456
Amino Acid Mutations A286V and T437M in the Nucleoprotein Attenuate H7N9 Viruses in Mice.
Ma S, Zhang B, Shi J, Yin X, Wang G, Cui P, Liu L, Deng G, Jiang Y, Li C, Chen H
Journal of virology 2020 Jan 6;94(2)
Journal of virology 2020 Jan 6;94(2)
The G Protein-Coupled Receptor FFAR2 Promotes Internalization during Influenza A Virus Entry.
Wang G, Jiang L, Wang J, Zhang J, Kong F, Li Q, Yan Y, Huang S, Zhao Y, Liang L, Li J, Sun N, Hu Y, Shi W, Deng G, Chen P, Liu L, Zeng X, Tian G, Bu Z, Chen H, Li C
Journal of virology 2020 Jan 6;94(2)
Journal of virology 2020 Jan 6;94(2)
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Wang J, Li S, Wang J, Wu F, Chen Y, Zhang H, Guo Y, Lin Y, Li L, Yu X, Liu T, Zhao Y
Aging 2020 Jan 6;12(1):650-671
Aging 2020 Jan 6;12(1):650-671
Type 2 inflammation suppression by T-regulatory cells attenuates the eosinophil recruitment in mucosa of chronic sinusitis.
Chang L, Wang Z, Li S, Chen X, Li X, Zhao J, Lai X, Huang J, Wu X, Huang Z, Bellanti JA, Zheng SG, Zhang G
Clinical science (London, England : 1979) 2020 Jan 31;134(2):123-138
Clinical science (London, England : 1979) 2020 Jan 31;134(2):123-138
MiR-30 family members inhibit osteoblast differentiation by suppressing Runx2 under unloading conditions in MC3T3-E1 cells.
Zhang L, Li G, Wang K, Wang Y, Dong J, Wang H, Xu L, Shi F, Cao X, Hu Z, Zhang S
Biochemical and biophysical research communications 2020 Jan 29;522(1):164-170
Biochemical and biophysical research communications 2020 Jan 29;522(1):164-170
Bridging molecules are secreted from the skeletal muscle and potentially regulate muscle differentiation.
Chikazawa M, Shimizu M, Yamauchi Y, Sato R
Biochemical and biophysical research communications 2020 Jan 29;522(1):113-120
Biochemical and biophysical research communications 2020 Jan 29;522(1):113-120
Elevated lymphocyte specific protein 1 expression is involved in the regulation of leukocyte migration and immunosuppressive microenvironment in glioblastoma.
Cao JY, Guo Q, Guan GF, Zhu C, Zou CY, Zhang LY, Cheng W, Wang GL, Cheng P, Wu AH, Li GY
Aging 2020 Jan 29;12(2):1656-1684
Aging 2020 Jan 29;12(2):1656-1684
FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy.
Lin JZ, Wang WW, Hu TT, Zhu GY, Li LN, Zhang CY, Xu Z, Yu HB, Wu HF, Zhu JG
Cancer letters 2020 Jan 28;469:481-489
Cancer letters 2020 Jan 28;469:481-489
Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis.
Huang XY, Huang ZL, Huang J, Xu B, Huang XY, Xu YH, Zhou J, Tang ZY
Journal of experimental & clinical cancer research : CR 2020 Jan 23;39(1):20
Journal of experimental & clinical cancer research : CR 2020 Jan 23;39(1):20
MicroRNA-639 is Down-Regulated in Hepatocellular Carcinoma Tumor Tissue and Inhibits Proliferation and Migration of Human Hepatocellular Carcinoma Cells Through the KAT7/Wnt/β-Catenin Pathway.
Bai Z, Xia X, Lu J
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 19;26:e919241
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 19;26:e919241
Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis.
Akamatsu M, Vasan R, Serwas D, Ferrin MA, Rangamani P, Drubin DG
eLife 2020 Jan 17;9
eLife 2020 Jan 17;9
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
Sun G, Cao Y, Qian C, Wan Z, Zhu J, Guo J, Shi L
Aging 2020 Jan 16;12(2):1114-1127
Aging 2020 Jan 16;12(2):1114-1127
MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury.
Yan Z, Zang B, Gong X, Ren J, Wang R
Life sciences 2020 Jan 15;241:117118
Life sciences 2020 Jan 15;241:117118
Biomimetic anti-inflammatory nano-capsule serves as a cytokine blocker and M2 polarization inducer for bone tissue repair.
Yin C, Zhao Q, Li W, Zhao Z, Wang J, Deng T, Zhang P, Shen K, Li Z, Zhang Y
Acta biomaterialia 2020 Jan 15;102:416-426
Acta biomaterialia 2020 Jan 15;102:416-426
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R
Cells 2020 Jan 10;9(1)
Cells 2020 Jan 10;9(1)
Reverting chemoresistance of targeted agents by a ultrasoluble dendritic nanocapsule.
Hu Q, Wu W, Wang M, Shao S, Jin P, Chen Q, Bai H, Zhao X, Huang J, Wang J, Tang G, Liang T
Journal of controlled release : official journal of the Controlled Release Society 2020 Jan 10;317:67-77
Journal of controlled release : official journal of the Controlled Release Society 2020 Jan 10;317:67-77
SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.
Liu X, Zhao J, Luan X, Li S, Zhai J, Liu J, Du Y
Placenta 2020 Jan 1;89:33-41
Placenta 2020 Jan 1;89:33-41
Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy.
Liu W, Fu R, Wang Z, Liu S, Tang C, Li L, Yin D
Journal of neuropathology and experimental neurology 2020 Jan 1;79(1):46-61
Journal of neuropathology and experimental neurology 2020 Jan 1;79(1):46-61
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S
Developmental biology 2020 Jan 1;457(1):150-162
Developmental biology 2020 Jan 1;457(1):150-162
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Bai Y, Qiao L, Xie N, Li Y, Nie Y, Pan Y, Shi Y, Wang J, Liu N
Cancer medicine 2020 Feb;9(4):1503-1514
Cancer medicine 2020 Feb;9(4):1503-1514
Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer.
Zhu CL, Huang Q
Digestive diseases and sciences 2020 Feb;65(2):489-499
Digestive diseases and sciences 2020 Feb;65(2):489-499
CARLo-5 as an oncogenic gene in endometrial carcinoma.
Zhao X, Zhang C, Wei X, Shi L, Dai S, Jia J, Wei S, Wang Y, Wang Y, Cheng J, Zhao L
Environmental and molecular mutagenesis 2020 Feb;61(2):256-265
Environmental and molecular mutagenesis 2020 Feb;61(2):256-265
Recombinant adiponectin peptide promotes neuronal survival after intracerebral haemorrhage by suppressing mitochondrial and ATF4-CHOP apoptosis pathways in diabetic mice via Smad3 signalling inhibition.
Wu X, Luo J, Liu H, Cui W, Guo W, Zhao L, Guo H, Bai H, Guo K, Feng D, Qu Y
Cell proliferation 2020 Feb;53(2):e12759
Cell proliferation 2020 Feb;53(2):e12759
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Ying Y, Li J, Xie H, Yan H, Jin K, He L, Ma X, Wu J, Xu X, Fang J, Wang X, Zheng X, Liu B, Xie L
Cell proliferation 2020 Feb;53(2):e12751
Cell proliferation 2020 Feb;53(2):e12751
Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome.
Zhou R, Li S, Liu J, Wu H, Yao G, Sun Y, Chen ZJ, Li W, Du Y
EBioMedicine 2020 Feb;52:102635
EBioMedicine 2020 Feb;52:102635
HOXC10 promotes proliferation and attenuates lipid accumulation of sheep bone marrow mesenchymal stem cells.
Ma M, Wang C, Ao Y, He N, Hao F, Liang H, Liu D
Molecular and cellular probes 2020 Feb;49:101491
Molecular and cellular probes 2020 Feb;49:101491
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Wu Q, Zhang M, Liu X, Zhang J, Wang H
International journal of molecular medicine 2020 Feb;45(2):475-484
International journal of molecular medicine 2020 Feb;45(2):475-484
Tumor suppressor LHPP regulates the proliferation of colorectal cancer cells via the PI3K/AKT pathway.
Hou B, Li W, Li J, Ma J, Xia P, Liu Z, Zeng Q, Zhang X, Chang D
Oncology reports 2020 Feb;43(2):536-548
Oncology reports 2020 Feb;43(2):536-548
ZYZ-803, a novel hydrogen sulfide-nitric oxide conjugated donor, promotes angiogenesis via cross-talk between STAT3 and CaMKII.
Xiong Y, Chang LL, Tran B, Dai T, Zhong R, Mao YC, Zhu YZ
Acta pharmacologica Sinica 2020 Feb;41(2):218-228
Acta pharmacologica Sinica 2020 Feb;41(2):218-228
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
Chen M, Zhu LL, Su JL, Li GL, Wang J, Zhang YN
Human & experimental toxicology 2020 Feb;39(2):173-181
Human & experimental toxicology 2020 Feb;39(2):173-181
ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.
Li K, Wu JL, Qin B, Fan Z, Tang Q, Lu W, Zhang H, Xing F, Meng M, Zou S, Wei W, Chen H, Cai J, Wang H, Zhang H, Cai J, Fang L, Bian X, Chen C, Lan P, Ghesquière B, Fang L, Lee MH
Cell research 2020 Feb;30(2):163-178
Cell research 2020 Feb;30(2):163-178
The MicroRNA-382-5p/MXD1 Axis Relates to Breast Cancer Progression and Promotes Cell Malignant Phenotypes.
Zhang X, Zhao H, Zhang Y, Yang X, Zhang J, Yi M, Zhang C
The Journal of surgical research 2020 Feb;246:442-449
The Journal of surgical research 2020 Feb;246:442-449
α5-nAChR contributes to epithelial-mesenchymal transition and metastasis by regulating Jab1/Csn5 signalling in lung cancer.
Chen X, Jia Y, Zhang Y, Zhou D, Sun H, Ma X
Journal of cellular and molecular medicine 2020 Feb;24(4):2497-2506
Journal of cellular and molecular medicine 2020 Feb;24(4):2497-2506
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
He H, Xu C, Zheng L, Wang K, Jin M, Sun Y, Yue Z
Molecular medicine reports 2020 Feb;21(2):597-606
Molecular medicine reports 2020 Feb;21(2):597-606
Isoprenaline protects intestinal stem cells from chemotherapy-induced damage.
Zeng H, Li H, Yue M, Fan Y, Cheng J, Wu X, Xu R, Yang W, Li M, Tang J, Chen H, Kuang B, Fan G, Zhu Q, Shao L
British journal of pharmacology 2020 Feb;177(3):687-700
British journal of pharmacology 2020 Feb;177(3):687-700
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage.
Xie Y, Peng J, Pang J, Guo K, Zhang L, Yin S, Zhou J, Gu L, Tu T, Mu Q, Liao Y, Zhang X, Chen L, Jiang Y
Journal of neurochemistry 2020 Feb;152(3):368-380
Journal of neurochemistry 2020 Feb;152(3):368-380
Geniposide reduces cholesterol accumulation and increases its excretion by regulating the FXR-mediated liver-gut crosstalk of bile acids.
Liu J, Li Y, Sun C, Liu S, Yan Y, Pan H, Fan M, Xue L, Nie C, Zhang H, Qian H, Ying H, Wang L
Pharmacological research 2020 Feb;152:104631
Pharmacological research 2020 Feb;152:104631
The expression of glucose transporters and mitochondrial division and fusion proteins in rats exposed to hypoxic preconditioning to attenuate propofol neurotoxicity.
Xiao F, Lv J, Liang YB, Chen YH, Tu YB, Guan RC, Li L, Xie YB
The International journal of neuroscience 2020 Feb;130(2):161-169
The International journal of neuroscience 2020 Feb;130(2):161-169
Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours.
Huang M, Yang W, Zhu J, Mariño-Enríquez A, Zhu C, Chen J, Wu Y, Quan Y, Qiu H, Li X, Chai L, Fletcher JA, Ou WB
British journal of cancer 2020 Feb;122(3):372-381
British journal of cancer 2020 Feb;122(3):372-381
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Lou L, Tian M, Chang J, Li F, Zhang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
BRD7 suppresses invasion and metastasis in breast cancer by negatively regulating YB1-induced epithelial-mesenchymal transition.
Niu W, Luo Y, Zhou Y, Li M, Wu C, Duan Y, Wang H, Fan S, Li Z, Xiong W, Li X, Li G, Ren C, Li H, Zhou M
Journal of experimental & clinical cancer research : CR 2020 Feb 7;39(1):30
Journal of experimental & clinical cancer research : CR 2020 Feb 7;39(1):30
The placental growth factor attenuates intimal hyperplasia in vein grafts by improving endothelial dysfunction.
Zhang J, Shi J, Ma H, Liu L, He L, Qin C, Zhang D, Guo Y, Gong R
European journal of pharmacology 2020 Feb 5;868:172856
European journal of pharmacology 2020 Feb 5;868:172856
RETRACTED: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing.
Chen X, Xu M, Xu X, Zeng K, Liu X, Sun L, Pan B, He B, Pan Y, Sun H, Xia X, Wang S
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):599-612
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):599-612
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
Qi S, Zhao F, Li Z, Liang F, Yu S
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, Zhu Q, Bukhari AA, Cao C, Su D, Liu Y, Liang X
Cell death & disease 2020 Feb 24;11(2):146
Cell death & disease 2020 Feb 24;11(2):146
Both IDO1 and TDO contribute to the malignancy of gliomas via the Kyn-AhR-AQP4 signaling pathway.
Du L, Xing Z, Tao B, Li T, Yang D, Li W, Zheng Y, Kuang C, Yang Q
Signal transduction and targeted therapy 2020 Feb 21;5(1):10
Signal transduction and targeted therapy 2020 Feb 21;5(1):10
Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma.
Shih JH, Chen HY, Lin SC, Yeh YC, Shen R, Lang YD, Wu DC, Chen CY, Chen RH, Chou TY, Jou YS
Nucleic acids research 2020 Feb 20;48(3):1175-1191
Nucleic acids research 2020 Feb 20;48(3):1175-1191
Interactions between Viperin, Vesicle-Associated Membrane Protein A, and Hepatitis C Virus Protein NS5A Modulate Viperin Activity and NS5A Degradation.
Ghosh S, Patel AM, Grunkemeyer TJ, Dumbrepatil AB, Zegalia K, Kennedy RT, Marsh ENG
Biochemistry 2020 Feb 18;59(6):780-789
Biochemistry 2020 Feb 18;59(6):780-789
[Mediated pathways of exosomes uptake by stem cells of apical papilla].
Gao XM, Zou XY, Yue L
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2020 Feb 18;52(1):43-50
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2020 Feb 18;52(1):43-50
Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.
Yan W, Long P, Wei D, Yan W, Zheng X, Chen G, Wang J, Zhang Z, Chen T, Chen M
BMC ophthalmology 2020 Feb 18;20(1):55
BMC ophthalmology 2020 Feb 18;20(1):55
Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.
Fan J, Ren D, Wang J, Liu X, Zhang H, Wu M, Yang G
Cell death & disease 2020 Feb 18;11(2):126
Cell death & disease 2020 Feb 18;11(2):126
Conditioned medium derived from FGF-2-modified GMSCs enhances migration and angiogenesis of human umbilical vein endothelial cells.
Jin S, Yang C, Huang J, Liu L, Zhang Y, Li S, Zhang L, Sun Q, Yang P
Stem cell research & therapy 2020 Feb 18;11(1):68
Stem cell research & therapy 2020 Feb 18;11(1):68
Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.
Wang Y, Ji L, Peng Z, Lai R, Zhang X, Xu Y, Chen Z, Liu R, Zhong Y, Hu H, Wang L
Molecular and cellular endocrinology 2020 Feb 15;502:110674
Molecular and cellular endocrinology 2020 Feb 15;502:110674
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Xu K, Liu X, Yin D, Ren G, Zhao Y
Life sciences 2020 Feb 15;243:117270
Life sciences 2020 Feb 15;243:117270
A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits the proliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling.
Fan Z, Xu Q, Wang C, Lin X, Zhang Q, Wu N
International journal of biological macromolecules 2020 Feb 15;145:154-164
International journal of biological macromolecules 2020 Feb 15;145:154-164
Targeted silencing of miRNA-132-3p expression rescues disuse osteopenia by promoting mesenchymal stem cell osteogenic differentiation and osteogenesis in mice.
Hu Z, Zhang L, Wang H, Wang Y, Tan Y, Dang L, Wang K, Sun Z, Li G, Cao X, Zhang S, Shi F, Zhang G
Stem cell research & therapy 2020 Feb 13;11(1):58
Stem cell research & therapy 2020 Feb 13;11(1):58
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Ayanlaja AA, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, Zhang L, Xiong Y, Kambey PA, Gao D
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Electrical Muscle Stimulation Accelerates Functional Recovery After Nerve Injury.
Fu T, Jiang L, Peng Y, Li Z, Liu S, Lu J, Zhang F, Zhang J
Neuroscience 2020 Feb 1;426:179-188
Neuroscience 2020 Feb 1;426:179-188
IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane.
Yang X, Yan H, Jiang N, Yu Z, Yuan J, Ni Z, Fang W
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F338-F353
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F338-F353
GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy.
Gao M, Liu L, Wang X, Mak HY, Liu G, Yang H
Human molecular genetics 2020 Feb 1;29(3):432-443
Human molecular genetics 2020 Feb 1;29(3):432-443
Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME.
Zheng X, Zhong T, Ma Y, Wan X, Qin A, Yao B, Zou H, Song Y, Yin D
Life sciences 2020 Feb 1;242:117186
Life sciences 2020 Feb 1;242:117186
MiR-21 modulates the polarization of macrophages and increases the effects of M2 macrophages on promoting the chemoresistance of ovarian cancer.
An Y, Yang Q
Life sciences 2020 Feb 1;242:117162
Life sciences 2020 Feb 1;242:117162
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Zhang P, Yin Y, Wang T, Li W, Li C, Zeng X, Yang W, Zhang R, Tang Y, Shi L, Li R, Tao K
Free radical biology & medicine 2020 Feb 1;147:23-36
Free radical biology & medicine 2020 Feb 1;147:23-36
Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification.
Cen Z, Chen Y, Chen S, Wang H, Yang D, Zhang H, Wu H, Wang L, Tang S, Ye J, Shen J, Wang H, Fu F, Chen X, Xie F, Liu P, Xu X, Cao J, Cai P, Pan Q, Li J, Yang W, Shan PF, Li Y, Liu JY, Zhang B, Luo W
Brain : a journal of neurology 2020 Feb 1;143(2):491-502
Brain : a journal of neurology 2020 Feb 1;143(2):491-502
The biologically functional identification of a novel TIM3-binding peptide P26 in vitro and in vivo.
Zhong T, Zhao C, Wang S, Tao D, Ma S, Shou C
Cancer chemotherapy and pharmacology 2020 Dec;86(6):783-792
Cancer chemotherapy and pharmacology 2020 Dec;86(6):783-792
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Zhu L, Duan W, Wu G, Zhang D, Wang L, Chen D, Chen Z, Yang B
Annals of translational medicine 2020 Dec;8(23):1586
Annals of translational medicine 2020 Dec;8(23):1586
Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation.
Wang M, Hu HH, Chen YY, Chen L, Wu XQ, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Dec;79:153323
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Dec;79:153323
Let-7b regulates the adriamycin resistance of chronic myelogenous leukemia by targeting AURKB in K562/ADM cells.
Zhou X, Ma X, Sun H, Li X, Cao H, Jiang Y, Wang P, Xie S, Li Y, Sun Y
Leukemia & lymphoma 2020 Dec;61(14):3451-3459
Leukemia & lymphoma 2020 Dec;61(14):3451-3459
Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing.
Yadavalli T, Suryawanshi R, Koganti R, Hopkins J, Ames J, Koujah L, Iqbal A, Madavaraju K, Agelidis A, Shukla D
Science advances 2020 Dec;6(49)
Science advances 2020 Dec;6(49)
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao X, Luo J, Qi W, Song BL
Nature 2020 Dec;588(7838):479-484
Nature 2020 Dec;588(7838):479-484
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Yang X, Li Y, Chen L, Xu M, Wu J, Zhang P, Nel D, Sun B
Pharmaceutical biology 2020 Dec;58(1):686-694
Pharmaceutical biology 2020 Dec;58(1):686-694
Dendrobium candidum aqueous extract attenuates isoproterenol-induced cardiac hypertrophy through the ERK signalling pathway.
Cao YY, Li K, Li Y, Tian XT, Ba HX, Wang A, Li XH
Pharmaceutical biology 2020 Dec;58(1):176-183
Pharmaceutical biology 2020 Dec;58(1):176-183
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
E L, Jiang H
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Pharmaceutical biology 2020 Dec;58(1):1077-1084
LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway.
Feng Y, Tan BZ
Molecular and cellular biochemistry 2020 Dec;475(1-2):185-194
Molecular and cellular biochemistry 2020 Dec;475(1-2):185-194
Oral cancer cell‑derived exosomes modulate natural killer cell activity by regulating the receptors on these cells.
Zhu X, Qin X, Wang X, Wang Y, Cao W, Zhang J, Chen W
International journal of molecular medicine 2020 Dec;46(6):2115-2125
International journal of molecular medicine 2020 Dec;46(6):2115-2125
Aberrant methylation‑mediated decrease of lncRNA HNF1A‑AS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT.
Shi Y, Zhang Q, Xie M, Feng Y, Ma S, Yi C, Wang Z, Li Y, Liu X, Liu H, Yang H, Yan Y, Zhang Y, Ren X, Luo H
Oncology reports 2020 Dec;44(6):2503-2516
Oncology reports 2020 Dec;44(6):2503-2516
Protective effects of rapamycin on the retinal vascular bed during the vaso-obliteration phase in mouse oxygen-induced retinopathy model.
Zhang J, Zhu M, Ruan L, Jiang C, Yang Q, Chang Q, Huang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):15822-15836
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):15822-15836
Bexarotene promotes microglia/macrophages - Specific brain - Derived Neurotrophic factor expression and axon sprouting after traumatic brain injury.
He J, Huang Y, Liu H, Sun X, Wu J, Zhang Z, Liu L, Zhou C, Jiang S, Huang Z, Zhong J, Guo Z, Jiang L, Cheng C
Experimental neurology 2020 Dec;334:113462
Experimental neurology 2020 Dec;334:113462
Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity.
Zachari M, Longo M, Ganley IG
Life science alliance 2020 Dec;3(12)
Life science alliance 2020 Dec;3(12)
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
Dong M, Xiao Q, Hu J, Cheng F, Zhang P, Zong W, Tang Q, Li X, Mao F, He Y, Yu X, Wan F, Lei T, Guo D, Wang B
Cancer gene therapy 2020 Dec;27(12):878-897
Cancer gene therapy 2020 Dec;27(12):878-897
circRNA 001306 enhances hepatocellular carcinoma growth by up-regulating CDK16 expression via sponging miR-584-5p.
Liu Q, Wang C, Jiang Z, Li S, Li F, Tan HB, Yue SY
Journal of cellular and molecular medicine 2020 Dec;24(24):14306-14315
Journal of cellular and molecular medicine 2020 Dec;24(24):14306-14315
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
Hou HW, Xue P, Wang Y, Li YK
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
Salvianolic acid B alleviates myocardial ischemic injury by promoting mitophagy and inhibiting activation of the NLRP3 inflammasome.
Hu Y, Wang X, Li Q, Pan Y, Xu L
Molecular medicine reports 2020 Dec;22(6):5199-5208
Molecular medicine reports 2020 Dec;22(6):5199-5208
1,25(OH)2D3 inhibits osteogenic differentiation through activating β‑catenin signaling via downregulating bone morphogenetic protein 2.
Han X, Zhu N, Wang Y, Cheng G
Molecular medicine reports 2020 Dec;22(6):5023-5032
Molecular medicine reports 2020 Dec;22(6):5023-5032
IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.
Zhu S, Wang H, Zhang Z, Ma M, Zheng Z, Xu X, Sun T
Molecular medicine reports 2020 Dec;22(6):4837-4847
Molecular medicine reports 2020 Dec;22(6):4837-4847
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Li J, Chen J, Hu Z, Xu W
Oncology letters 2020 Dec;20(6):367
Oncology letters 2020 Dec;20(6):367
Forkhead box P3 promotes breast cancer cell apoptosis by regulating programmed cell death 4 expression.
Fan D, Zeng C, Wang S, Han J, Zhu L, Zhao H, Zhang Y, Lu J, Xu Y
Oncology letters 2020 Dec;20(6):292
Oncology letters 2020 Dec;20(6):292
Inhibition of Histone Deacetylase 6 by Tubastatin A Attenuates the Progress of Osteoarthritis via Improving Mitochondrial Function.
Zheng Y, Chen Y, Lu X, Weng Q, Dai G, Yu Y, Yu K, Gao W
The American journal of pathology 2020 Dec;190(12):2376-2386
The American journal of pathology 2020 Dec;190(12):2376-2386
Reduced expression of α2 integrin is involved in T-2 toxin-induced matrix degradation in C28/I2 cells and cartilages from rats administrated with T-2 toxin.
Zhang M, Wang H, Wang M, Liu Y, Liao Y, Liu Y, Zhang Y, Ma T, Chen J
Toxicon : official journal of the International Society on Toxinology 2020 Dec;188:127-133
Toxicon : official journal of the International Society on Toxinology 2020 Dec;188:127-133
Cytoskeleton protein 4.1R regulates B-cell fate by modulating the canonical NF-κB pathway.
Liang T, Guo Y, Li M, Ding C, Sang S, Zhou T, Shao Q, Liu X, Lu J, Ji Z, Wang T, Kang Q
Immunology 2020 Dec;161(4):314-324
Immunology 2020 Dec;161(4):314-324
TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2.
Sun N, Jiang L, Ye M, Wang Y, Wang G, Wan X, Zhao Y, Wen X, Liang L, Ma S, Liu L, Bu Z, Chen H, Li C
Protein & cell 2020 Dec;11(12):894-914
Protein & cell 2020 Dec;11(12):894-914
The interplay between ATF2 and NEAT1 contributes to lung adenocarcinoma progression.
Liu J, Li K, Wang R, Chen S, Wu J, Li X, Ning Q, Yang G, Pang Y
Cancer cell international 2020 Dec 9;20(1):594
Cancer cell international 2020 Dec 9;20(1):594
Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity.
Prunk M, Perišić Nanut M, Jakoš T, Sabotič J, Švajger U, Kos J
Cancers 2020 Dec 6;12(12)
Cancers 2020 Dec 6;12(12)
lncRNA RP11-624L4.1 Is Associated with Unfavorable Prognosis and Promotes Proliferation via the CDK4/6-Cyclin D1-Rb-E2F1 Pathway in NPC.
Zhou L, Liu R, Liang X, Zhang S, Bi W, Yang M, He Y, Jin J, Li S, Yang X, Fu J, Zhang P
Molecular therapy. Nucleic acids 2020 Dec 4;22:1025-1039
Molecular therapy. Nucleic acids 2020 Dec 4;22:1025-1039
Effects of dietary carbohydrate sources on lipid metabolism and SUMOylation modification in the liver tissues of yellow catfish.
Yang SB, Zhao T, Wu LX, Xu YC, Tan XY
The British journal of nutrition 2020 Dec 28;124(12):1241-1250
The British journal of nutrition 2020 Dec 28;124(12):1241-1250
Significance of gastrointestinal tract in the therapeutic mechanisms of exercise in depression: Synchronism between brain and intestine through GBA.
Liu Y, Xu F, Liu S, Liu G, Yang X, Gao W, Fan K, Zhao H, Ma J
Progress in neuro-psychopharmacology & biological psychiatry 2020 Dec 20;103:109971
Progress in neuro-psychopharmacology & biological psychiatry 2020 Dec 20;103:109971
CircRNA circ-0038718 promotes hepatocellular carcinoma progression through sponging miR-139-3p.
Sun R, Li H, Li J, Shen S, Cui G, Dong G
Biochemical and biophysical research communications 2020 Dec 17;533(4):845-852
Biochemical and biophysical research communications 2020 Dec 17;533(4):845-852
Combination of metformin and RG7388 enhances inhibition of growth and induction of apoptosis of ovarian cancer cells through the PI3K/AKT/mTOR pathway.
Cui Y, Zhou J, Rong F
Biochemical and biophysical research communications 2020 Dec 17;533(4):665-671
Biochemical and biophysical research communications 2020 Dec 17;533(4):665-671
Lipid peroxidation aggravates anti-tuberculosis drug-induced liver injury: Evidence of ferroptosis induction.
Pan Y, Tang P, Cao J, Song Q, Zhu L, Ma S, Zhang J
Biochemical and biophysical research communications 2020 Dec 17;533(4):1512-1518
Biochemical and biophysical research communications 2020 Dec 17;533(4):1512-1518
Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Yang Y, Liao Z, Xiao Q
Biochemical and biophysical research communications 2020 Dec 17;533(4):1226-1232
Biochemical and biophysical research communications 2020 Dec 17;533(4):1226-1232
Genetic code expansion in mammalian cells: A plasmid system comparison.
Zhou W, Wesalo JS, Liu J, Deiters A
Bioorganic & medicinal chemistry 2020 Dec 15;28(24):115772
Bioorganic & medicinal chemistry 2020 Dec 15;28(24):115772
Dexmedetomidine alleviates neurobehavioral impairments and myelination deficits following lipopolysaccharide exposure in early postnatal rats.
Wu Z, Xue H, Zhang Y, Zhao P
Life sciences 2020 Dec 15;263:118556
Life sciences 2020 Dec 15;263:118556
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Liu X, Meng L, Li X, Li D, Liu Q, Chen Y, Li X, Bu W, Sun H
International journal of oral science 2020 Dec 14;12(1):34
International journal of oral science 2020 Dec 14;12(1):34
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Chen Q, Wang Y, Jiao F, Shi C, Pei M, Wang L, Gong Z
Scientific reports 2020 Dec 14;10(1):21850
Scientific reports 2020 Dec 14;10(1):21850
Inhibition of Exo-miR-19a-3p derived from cardiomyocytes promotes angiogenesis and improves heart function in mice with myocardial infarction via targeting HIF-1α.
Gou L, Xue C, Tang X, Fang Z
Aging 2020 Dec 11;12(23):23609-23618
Aging 2020 Dec 11;12(23):23609-23618
Tectorigenin Inhibits Glioblastoma Proliferation by G0/G1 Cell Cycle Arrest.
Yeh LT, Hsu LS, Chung YH, Chen CJ
Medicina (Kaunas, Lithuania) 2020 Dec 10;56(12)
Medicina (Kaunas, Lithuania) 2020 Dec 10;56(12)
The peptide mimicking small extracellular ring domain of CD82 inhibits epithelial-mesenchymal transition by downregulating Wnt pathway and upregulating hippo pathway.
He X, Huang X, Wang C, Luan M, Li Y, Ma X, Ma K
Biochemical and biophysical research communications 2020 Dec 10;533(3):338-345
Biochemical and biophysical research communications 2020 Dec 10;533(3):338-345
Metformin protects chondrocytes against IL-1β induced injury by regulation of the AMPK/NF-κ B signaling pathway.
Zhang M, Liu Y, Huan Z, Wang Y, Xu J
Die Pharmazie 2020 Dec 1;75(12):632-636
Die Pharmazie 2020 Dec 1;75(12):632-636
Hydrogen sulfide accumulates LDL receptor precursor via downregulating PCSK9 in HepG2 cells.
Huang Y, Ning K, Li WW, Lin G, Hou CL, Wang MJ, Zhu YC
American journal of physiology. Cell physiology 2020 Dec 1;319(6):C1082-C1096
American journal of physiology. Cell physiology 2020 Dec 1;319(6):C1082-C1096
Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Lung Injury in Rat Model of Bronchopulmonary Dysplasia by Affecting Cell Survival and Angiogenesis.
You J, Zhou O, Liu J, Zou W, Zhang L, Tian D, Dai J, Luo Z, Liu E, Fu Z, Zou L
Stem cells and development 2020 Dec 1;29(23):1520-1532
Stem cells and development 2020 Dec 1;29(23):1520-1532
TL1A primed dendritic cells activation exacerbated chronic murine colitis.
Han F, Song J, Jia W, Yang M, Wang D, Zhang H, Shih DQ, Targan SR, Zhang X
Life sciences 2020 Dec 1;262:118220
Life sciences 2020 Dec 1;262:118220
Discovery of a novel rice-derived peptide with significant anti-gout potency.
Liu N, Meng B, Zeng L, Yin S, Hu Y, Li S, Fu Y, Zhang X, Xie C, Shu L, Yang M, Wang Y, Yang X
Food & function 2020 Dec 1;11(12):10542-10553
Food & function 2020 Dec 1;11(12):10542-10553
Trophoblast H2S Maintains Early Pregnancy via Regulating Maternal-Fetal Interface Immune Hemostasis.
Wang B, Xu T, Li Y, Wang W, Lyu C, Luo D, Yang Q, Ning N, Chen ZJ, Yan J, Chen DB, Li J
The Journal of clinical endocrinology and metabolism 2020 Dec 1;105(12):e4275-89
The Journal of clinical endocrinology and metabolism 2020 Dec 1;105(12):e4275-89
Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation.
Han J, Kan J, Wang X, Yuan Q, Song X, Huang M, Wu H
Translational cancer research 2020 Aug;9(8):4715-4725
Translational cancer research 2020 Aug;9(8):4715-4725
Minocycline prevents the depressive-like behavior through inhibiting the release of HMGB1 from microglia and neurons.
Wang B, Huang X, Pan X, Zhang T, Hou C, Su WJ, Liu LL, Li JM, Wang YX
Brain, behavior, and immunity 2020 Aug;88:132-143
Brain, behavior, and immunity 2020 Aug;88:132-143
Cadmium induces cell growth in A549 and HELF cells via autophagy-dependent glycolysis.
Wang X, Li Z, Gao Z, Li Q, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104834
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104834
Inhibition of Phosphatidylinositol 3-Kinase γ by IPI-549 Attenuates Abdominal Aortic Aneurysm Formation in Mice.
Liu R, Huang J, Ge Y, Liu S, Huang T, Cai H, Pan B, Zhang Q, Yang P, Liao M, Xu B, Wang W
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2020 Aug;60(2):254-263
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2020 Aug;60(2):254-263
TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening.
Zhang L, Liu L, Li X, Zhang X, Zhao J, Luo Y, Guo X, Zhao T
International journal of molecular medicine 2020 Aug;46(2):663-674
International journal of molecular medicine 2020 Aug;46(2):663-674
Heparanase potentiates the invasion and migration of pancreatic cancer cells via epithelial‑to‑mesenchymal transition through the Wnt/β‑catenin pathway.
Wang C, Wei Y, Wang G, Zhou Y, Zhang J, Xu K
Oncology reports 2020 Aug;44(2):711-721
Oncology reports 2020 Aug;44(2):711-721
PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β‑catenin signaling pathway.
Ma D, Hou L, Xia H, Li H, Fan H, Jia X, Niu Z
Oncology reports 2020 Aug;44(2):533-542
Oncology reports 2020 Aug;44(2):533-542
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Zhou YQ, Liu DQ, Chen SP, Chen N, Sun J, Wang XM, Cao F, Tian YK, Ye DW
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer.
Huang Y, Xiang Y, Xie Z, Cai Y, Yang Q, Huang H, Chen Z, Xiao Z, He Q
Clinical & experimental metastasis 2020 Aug;37(4):477-487
Clinical & experimental metastasis 2020 Aug;37(4):477-487
STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.
Yang J, Jiang Q, Yu X, Xu T, Wang Y, Deng J, Liu Y, Chen Y
CNS neuroscience & therapeutics 2020 Aug;26(8):851-861
CNS neuroscience & therapeutics 2020 Aug;26(8):851-861
Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner.
Huang L, Yan W, Cai B, Song Y, Lv Q, Wang G, Wang L, Wang Z
Biomaterials 2020 Aug;250:120021
Biomaterials 2020 Aug;250:120021
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.
Xu S, Chen D, Chen D, Hu Q, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2020 Aug;247:108786
Veterinary microbiology 2020 Aug;247:108786
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Cong LH, Li T, Wang H, Wu YN, Wang SP, Zhao YY, Zhang GQ, Duan J
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Caprin-1 promotes HepG2 cell proliferation, invasion and migration and is associated with poor prognosis in patients with liver cancer.
Guo XM, Zhu FF, Pan LW, Chen JL, Lai JC, Wu HX, Shu JC
Oncology letters 2020 Aug;20(2):1761-1771
Oncology letters 2020 Aug;20(2):1761-1771
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner.
Jian L, Xie J, Guo S, Yu H, Chen R, Tao K, Yang C, Li K, Liu S
Oncology letters 2020 Aug;20(2):1441-1451
Oncology letters 2020 Aug;20(2):1441-1451
Prazosin inhibits the proliferation, migration and invasion, but promotes the apoptosis of U251 and U87 cells via the PI3K/AKT/mTOR signaling pathway.
Zhang J, Fan J
Experimental and therapeutic medicine 2020 Aug;20(2):1145-1152
Experimental and therapeutic medicine 2020 Aug;20(2):1145-1152
Selenoprotein S attenuates endothelial dysfunction in a diabetic vascular chip.
Zhong Y, Yu S, Yu H, Yao J, Men L, Li Y, Wang Q, Du J
Experimental gerontology 2020 Aug;137:110963
Experimental gerontology 2020 Aug;137:110963
Tetramethylpyrazine attenuates endotoxin-induced retinal inflammation by inhibiting microglial activation via the TLR4/NF-κB signalling pathway.
Han X, Chen X, Chen S, Luo Q, Liu X, He A, He S, Qiu J, Chen P, Wu Y, Zhuang J, Yang M, Wu C, Wu N, Yang Y, Ge J, Zhuang J, Yu K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110273
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110273
circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells.
Ye Y, Zhao L, Li Q, Xi C, Li Y, Li Z
Thoracic cancer 2020 Aug;11(8):2196-2208
Thoracic cancer 2020 Aug;11(8):2196-2208
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Li JM, Yang F, Li J, Yuan WQ, Wang H, Luo YQ
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling.
Geng A, Wu T, Cai C, Song W, Wang J, Yu QC, Zeng YA
eLife 2020 Aug 4;9
eLife 2020 Aug 4;9
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Anti-inflammatory effect of Ganluyin, a Chinese classic prescription, in chronic pharyngitis rat model.
Chen YH, Luo R, Lei SS, Li B, Zhou FC, Wang HY, Chen X, He X, Wang YZ, Zhan LH, Lu TT, Su J, Yu QX, Li B, Lv GY, Chen SH
BMC complementary medicine and therapies 2020 Aug 28;20(1):265
BMC complementary medicine and therapies 2020 Aug 28;20(1):265
GOLGA4, A Golgi matrix protein, is dispensable for spermatogenesis and male fertility in mice.
Guo S, Chunyu Lv, Ouyang S, Wang X, Liao A, Yuan S
Biochemical and biophysical research communications 2020 Aug 27;529(3):642-646
Biochemical and biophysical research communications 2020 Aug 27;529(3):642-646
SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.
Ma Y, Zhu S, Lv T, Gu X, Feng H, Zhen J, Xin W, Wan Q
iScience 2020 Aug 21;23(8):101428
iScience 2020 Aug 21;23(8):101428
Levobupivacaine inhibits proliferation and promotes apoptosis of breast cancer cells by suppressing the PI3K/Akt/mTOR signalling pathway.
Kwakye AK, Kampo S, Lv J, Ramzan MN, Richard SA, Falagán AA, Agudogo J, Atito-Narh E, Yan Q, Wen QP
BMC research notes 2020 Aug 17;13(1):386
BMC research notes 2020 Aug 17;13(1):386
Exosomal miR-532-5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5.
Zhu G, Yang X, Peng C, Yu L, Hao Y
Experimental cell research 2020 Aug 15;393(2):112109
Experimental cell research 2020 Aug 15;393(2):112109
Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells.
Jia C, Tang H, Yang Y, Yuan S, Han T, Fang M, Huang S, Hu R, Li C, Geng W
Biochemical and biophysical research communications 2020 Aug 13;529(1):43-50
Biochemical and biophysical research communications 2020 Aug 13;529(1):43-50
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Wu J, He J, Tian X, Li H, Wen Y, Shao Q, Cheng C, Wang G, Sun X
Neuroscience 2020 Aug 1;440:160-174
Neuroscience 2020 Aug 1;440:160-174
Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro.
Hao P, Yue F, Xian X, Ren Q, Cui H, Wang Y
Life sciences 2020 Aug 1;254:117632
Life sciences 2020 Aug 1;254:117632
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Liu W, Li Y, Feng S, Guan Y, Cao Y
Journal of biochemistry 2020 Aug 1;168(2):159-170
Journal of biochemistry 2020 Aug 1;168(2):159-170
Circulating Myeloid-derived Suppressor Cells Facilitate Invasion of Thyroid Cancer Cells by Repressing miR-486-3p.
Chen L, Xiong L, Hong S, Li J, Huo Z, Li Y, Chen S, Zhang Q, Zhao R, Gingold JA, Zhu X, Lv W, Li Y, Yu S, Xiao H
The Journal of clinical endocrinology and metabolism 2020 Aug 1;105(8)
The Journal of clinical endocrinology and metabolism 2020 Aug 1;105(8)
MAP kinase-interacting kinase 1 (MNK1) plays as a tumor suppressor in bladder cancer.
Chen Z, Xiao K, Zhang H, Liu C, Yang J, Liang H, Lin Z, Qin Z, Chen M, Ye Y
Translational cancer research 2020 Apr;9(4):2588-2598
Translational cancer research 2020 Apr;9(4):2588-2598
Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.
Guo X, Zhang Y, Lu C, Qu F, Jiang X
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):714-724
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):714-724
S-allylmercaptocysteine ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation and oxidative stress via nuclear factor kappa B and Keap1/Nrf2 pathways.
Mo M, Li S, Dong Z, Li C, Sun Y, Li A, Zhao Z
International immunopharmacology 2020 Apr;81:106273
International immunopharmacology 2020 Apr;81:106273
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Zhu R, Wei J, Liu H, Liu C, Wang L, Chen B, Li L, Jia Q, Tian Y, Li R, Zhao D, Mo F, Li Y, Gao S, Wang XD, Zhang D
The Journal of nutritional biochemistry 2020 Apr;78:108335
The Journal of nutritional biochemistry 2020 Apr;78:108335
Mortalin contributes to colorectal cancer by promoting proliferation and epithelial-mesenchymal transition.
Xu M, Zhang Y, Cui M, Wang X, Lin Z
IUBMB life 2020 Apr;72(4):771-781
IUBMB life 2020 Apr;72(4):771-781
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Chen KL, Wang HL, Jiang LZ, Qian Y, Yang CX, Chang WW, Zhong JF, Xing GD
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
Marrow-derived mesenchymal stem cells regulate the inflammatory response and repair alveolar type II epithelial cells in acute lung injury of rats.
Li Q, Chen X, Li J
The Journal of international medical research 2020 Apr;48(4):300060520909027
The Journal of international medical research 2020 Apr;48(4):300060520909027
MicroRNA-378-3p/5p represses proliferation and induces apoptosis of oral squamous carcinoma cells via targeting KLK4.
Cui Z, Bao X, Liu Q, Li Q, Huang L, Wang H, Jiao K
Clinical and experimental pharmacology & physiology 2020 Apr;47(4):713-724
Clinical and experimental pharmacology & physiology 2020 Apr;47(4):713-724
RUNX3 inhibits the invasion and migration of esophageal squamous cell carcinoma by reversing the epithelial‑mesenchymal transition through TGF‑β/Smad signaling.
Xiao Z, Tian Y, Jia Y, Shen Q, Jiang W, Chen G, Shang B, Shi M, Wang Z, Zhao X
Oncology reports 2020 Apr;43(4):1289-1299
Oncology reports 2020 Apr;43(4):1289-1299
Osteopontin accelerates the development and metastasis of bladder cancer via activating JAK1/STAT1 pathway.
Zhang N, Li F, Gao J, Zhang S, Wang Q
Genes & genomics 2020 Apr;42(4):467-475
Genes & genomics 2020 Apr;42(4):467-475
Lanthanum Chloride Impairs Learning and Memory and Induces Dendritic Spine Abnormality by Down-Regulating Rac1/PAK Signaling Pathway in Hippocampus of Offspring Rats.
Sun W, Yang J, Hong Y, Yuan H, Wang J, Zhang Y, Lu X, Jin C, Wu S, Cai Y
Cellular and molecular neurobiology 2020 Apr;40(3):459-475
Cellular and molecular neurobiology 2020 Apr;40(3):459-475
AMPK facilitates intestinal long-chain fatty acid uptake by manipulating CD36 expression and translocation.
Wu W, Wang S, Liu Q, Shan T, Wang X, Feng J, Wang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):4852-4869
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):4852-4869
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
Su L, Yao Y, Song W
Human cell 2020 Apr;33(2):337-346
Human cell 2020 Apr;33(2):337-346
N(6)-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation.
Zhao T, Sun D, Zhao M, Lai Y, Liu Y, Zhang Z
Environmental pollution (Barking, Essex : 1987) 2020 Apr;259:113908
Environmental pollution (Barking, Essex : 1987) 2020 Apr;259:113908
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
Shi W, Ma H, Liu T, Yan D, Luo P, Zhai M, Tao J, Huo S, Guo J, Li C, Lin J, Zhang C, Li S, Lv J, Lin L
Journal of cellular and molecular medicine 2020 Apr;24(8):4748-4761
Journal of cellular and molecular medicine 2020 Apr;24(8):4748-4761
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Chen Z, Yan X, Li K, Ling Y, Kang H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells.
Li Q, Zhai Y, Man X, Zhang S, An X
Cellular reprogramming 2020 Apr;22(2):82-89
Cellular reprogramming 2020 Apr;22(2):82-89
Long-term Production of Glycogen and Hepatic-Derived, Cell-Invasion-Promoting Chemokines by Ultrasound-Driven Hepatic-Differentiated Human Bone Marrow Mesenchymal Stem Cells.
Song L, Constanthin PE, Sun T, Li X, Xia Z, An L, Li F
Radiation research 2020 Apr;193(4):394-405
Radiation research 2020 Apr;193(4):394-405
Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy.
Lee AK, Pan D, Bao X, Hu M, Li F, Li CY
Radiation research 2020 Apr;193(4):305-317
Radiation research 2020 Apr;193(4):305-317
miR-4458 directly targets IGF1R to inhibit cell proliferation and promote apoptosis in hemangioma.
Wu M, Tang Y, Hu G, Yang C, Ye K, Liu X
Experimental and therapeutic medicine 2020 Apr;19(4):3017-3023
Experimental and therapeutic medicine 2020 Apr;19(4):3017-3023
Prior inhibition of AKT phosphorylation by BX795 can define a safer strategy to prevent herpes simplex virus-1 infection of the eye.
Yadavalli T, Suryawanshi R, Ali M, Iqbal A, Koganti R, Ames J, Aakalu VK, Shukla D
The ocular surface 2020 Apr;18(2):221-230
The ocular surface 2020 Apr;18(2):221-230
Self-Therapeutic Nanoparticle That Alters Tau Protein and Ameliorates Tauopathy Toward a Functional Nanomedicine to Tackle Alzheimer's.
Vimal SK, Zuo H, Wang Z, Wang H, Long Z, Bhattacharyya S
Small (Weinheim an der Bergstrasse, Germany) 2020 Apr;16(16):e1906861
Small (Weinheim an der Bergstrasse, Germany) 2020 Apr;16(16):e1906861
MiR-142-3p Attenuates Oxygen Glucose Deprivation/Reoxygenation-Induced Injury by Targeting FBXO3 in Human Neuroblastoma SH-SY5Y Cells.
Li J, Ma L
World neurosurgery 2020 Apr;136:e149-e157
World neurosurgery 2020 Apr;136:e149-e157
Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota-bile acid-farnesoid X receptor axis.
Li H, Xi Y, Xin X, Tian H, Hu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109915
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109915
Cytoplasmic ERα and NFκB Promote Cell Survival in Mouse Mammary Cancer Cell Lines.
Smart E, Alejo LH, Frasor J
Hormones & cancer 2020 Apr;11(2):76-86
Hormones & cancer 2020 Apr;11(2):76-86
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, Peng S, Sun X, Yu M, Chen H, Wang Y, Zhang L, Liu N, Du H, Zhao D, Zhang W
Aging and disease 2020 Apr;11(2):269-285
Aging and disease 2020 Apr;11(2):269-285
Nasal delivery of a CRMP2-derived CBD3 adenovirus improves cognitive function and pathology in APP/PS1 transgenic mice.
Qi B, Yang Y, Cheng Y, Sun D, Wang X, Khanna R, Ju W
Molecular brain 2020 Apr 9;13(1):58
Molecular brain 2020 Apr 9;13(1):58
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Zhong B, Liu M, Bai C, Ruan Y, Wang Y, Qiu L, Hong Y, Wang X, Li L, Li B
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Tacr3 in the lateral habenula differentially regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia.
Cui WQ, Zhang WW, Chen T, Li Q, Xu F, Mao-Ying QL, Mi WL, Wang YQ, Chu YX
Acta neuropathologica communications 2020 Apr 7;8(1):44
Acta neuropathologica communications 2020 Apr 7;8(1):44
Overexpression of SLC6A1 associates with drug resistance and poor prognosis in prostate cancer.
Chen C, Cai Z, Zhuo Y, Xi M, Lin Z, Jiang F, Liu Z, Wan Y, Zheng Y, Li J, Zhou X, Zhu J, Zhong W
BMC cancer 2020 Apr 6;20(1):289
BMC cancer 2020 Apr 6;20(1):289
Water extract from processed Polygonum multiflorum modulate gut microbiota and glucose metabolism on insulin resistant rats.
Gu W, Yang M, Bi Q, Zeng LX, Wang X, Dong JC, Li FJ, Yang XX, Li JP, Yu J
BMC complementary medicine and therapies 2020 Apr 5;20(1):107
BMC complementary medicine and therapies 2020 Apr 5;20(1):107
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.
Qin G, Wang X, Ye S, Li Y, Chen M, Wang S, Qin T, Zhang C, Li Y, Long Q, Hu H, Shi D, Li J, Zhang K, Zhai Q, Tang Y, Kang T, Lan P, Xie F, Lu J, Deng W
Nature communications 2020 Apr 3;11(1):1669
Nature communications 2020 Apr 3;11(1):1669
ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis.
Chen J, Ding C, Chen Y, Hu W, Lu Y, Wu W, Zhang Y, Yang B, Wu H, Peng C, Xie H, Zhou L, Wu J, Zheng S
Oncogenesis 2020 Apr 29;9(4):42
Oncogenesis 2020 Apr 29;9(4):42
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Chen HX, Liang FC, Gu P, Xu BL, Xu HJ, Wang WT, Hou JY, Xie DX, Chai XQ, An SJ
Cell death & disease 2020 Apr 27;11(4):288
Cell death & disease 2020 Apr 27;11(4):288
A novel ETV6-miR-429-CRKL regulatory circuitry contributes to aggressiveness of hepatocellular carcinoma.
Guo C, Gao C, Zhao D, Li J, Wang J, Sun X, Liu Q, Hao L, Greenaway FT, Tian Y, Liu S, Sun MZ
Journal of experimental & clinical cancer research : CR 2020 Apr 23;39(1):70
Journal of experimental & clinical cancer research : CR 2020 Apr 23;39(1):70
Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins.
Chen Y, Zheng J, Li X, Zhu L, Shao Z, Yan X, Zhu X
Cell reports 2020 Apr 21;31(3):107526
Cell reports 2020 Apr 21;31(3):107526
Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression-like behaviour via cannabinoid system in sleep deprivation rats.
Wang T, Niu K, Fan A, Bi N, Tao H, Chen XT, Wang HL
Behavioural brain research 2020 Apr 20;384:112545
Behavioural brain research 2020 Apr 20;384:112545
ASK1 inhibits browning of white adipose tissue in obesity.
Lucchini FC, Wueest S, Challa TD, Item F, Modica S, Borsigova M, Haim Y, Wolfrum C, Rudich A, Konrad D
Nature communications 2020 Apr 2;11(1):1642
Nature communications 2020 Apr 2;11(1):1642
Integrin Subunit Alpha 5 (ITGA5) Gene Circular RNA Sponges microRNA-107 in Colorectal Carcinoma Cells and Tissues and Regulates the Expression of the Forkhead Box J3 (FOXJ3) Gene.
Huang G, Ma J, Zhang L
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 19;26:e920623
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 19;26:e920623
Increased Collagen Turnover Impairs Tendon Microstructure and Stability in Integrin α2β1-Deficient Mice.
Kronenberg D, Michel PA, Hochstrat E, Wei M, Brinckmann J, Müller M, Frank A, Hansen U, Eckes B, Stange R
International journal of molecular sciences 2020 Apr 18;21(8)
International journal of molecular sciences 2020 Apr 18;21(8)
MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line.
Zhang Q, Ma XF, Dong MZ, Tan J, Zhang J, Zhuang LK, Liu SS, Xin YN
Lipids in health and disease 2020 Apr 16;19(1):76
Lipids in health and disease 2020 Apr 16;19(1):76
Characterisation of extraembryonic endoderm-like cells from mouse embryonic fibroblasts induced using chemicals alone.
He X, Chi G, Li M, Xu J, Zhang L, Song Y, Wang L, Li Y
Stem cell research & therapy 2020 Apr 16;11(1):157
Stem cell research & therapy 2020 Apr 16;11(1):157
FOXO4 expression associates with glioblastoma development and FOXO4 expression inhibits cell malignant phenotypes in vitro and in vivo.
Qi M, Sun LA, Jiang XC, Han YL, Wang L, Niu WH, Fei MX, Zhaba WD, Zheng LR, Zhou ML
Life sciences 2020 Apr 15;247:117436
Life sciences 2020 Apr 15;247:117436
MOB2 suppresses GBM cell migration and invasion via regulation of FAK/Akt and cAMP/PKA signaling.
Jiang K, Yao G, Hu L, Yan Y, Liu J, Shi J, Chang Y, Zhang Y, Liang D, Shen D, Zhang G, Meng S, Piao H
Cell death & disease 2020 Apr 14;11(4):230
Cell death & disease 2020 Apr 14;11(4):230
Astaxanthin (ATX) enhances the intestinal mucosal functions in immunodeficient mice.
Zhang L, Cao W, Gao Y, Yang R, Zhang X, Xu J, Tang Q
Food & function 2020 Apr 1;11(4):3371-3381
Food & function 2020 Apr 1;11(4):3371-3381
A low dose of AZD8055 enhances radiosensitivity of nasopharyngeal carcinoma cells by activating autophagy and apoptosis.
Chang L, Huang Z, Li S, Yao Z, Bao H, Wang Z, Li X, Chen X, Huang J, Zhang G
American journal of cancer research 2019;9(9):1922-1937
American journal of cancer research 2019;9(9):1922-1937
LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1α.
Zeng Z, Xu FY, Zheng H, Cheng P, Chen QY, Ye Z, Zhong JX, Deng SJ, Liu ML, Huang K, Li Q, Li W, Hu YH, Wang F, Wang CY, Zhao G
Theranostics 2019;9(18):5298-5314
Theranostics 2019;9(18):5298-5314
Hypoxia-induced feedback of HIF-1α and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization of p53 protein.
Liu M, Zhong J, Zeng Z, Huang K, Ye Z, Deng S, Chen H, Xu F, Li Q, Zhao G
Theranostics 2019;9(16):4795-4810
Theranostics 2019;9(16):4795-4810
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
Zhao J, Gao W, Cai X, Xu J, Zou D, Li Z, Hu B, Zheng Y
Theranostics 2019;9(10):2843-2855
Theranostics 2019;9(10):2843-2855
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W
American journal of cancer research 2019;9(10):2140-2155
American journal of cancer research 2019;9(10):2140-2155
Hydroxycarboxylic Acid Receptor 2 Is a Zika Virus Restriction Factor That Can Be Induced by Zika Virus Infection Through the IRE1-XBP1 Pathway.
Ma X, Luo X, Zhou S, Huang Y, Chen C, Huang C, Shen L, Zhang P, Liu C
Frontiers in cellular and infection microbiology 2019;9:480
Frontiers in cellular and infection microbiology 2019;9:480
Transcriptional Activation of Gstp1 by MEK/ERK Signaling Confers Chemo-Resistance to Cisplatin in Lung Cancer Stem Cells.
Li J, Ye T, Liu Y, Kong L, Sun Z, Liu D, Wang J, Xing HR
Frontiers in oncology 2019;9:476
Frontiers in oncology 2019;9:476
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, Xiao G, Li Z
Frontiers in oncology 2019;9:461
Frontiers in oncology 2019;9:461
Epigenetic-Mediated Downregulation of Zinc Finger Protein 671 (ZNF671) Predicts Poor Prognosis in Multiple Solid Tumors.
Zhang J, Zheng Z, Zheng J, Xie T, Tian Y, Li R, Wang B, Lin J, Xu A, Huang X, Yuan Y
Frontiers in oncology 2019;9:342
Frontiers in oncology 2019;9:342
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma.
Bai Y, Yang C, Wu R, Huang L, Song S, Li W, Yan P, Lin C, Li D, Zhang Y
Frontiers in oncology 2019;9:332
Frontiers in oncology 2019;9:332
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
Novel Breast-Specific Long Non-coding RNA LINC00993 Acts as a Tumor Suppressor in Triple-Negative Breast Cancer.
Guo S, Jian L, Tao K, Chen C, Yu H, Liu S
Frontiers in oncology 2019;9:1325
Frontiers in oncology 2019;9:1325
Influence of microcystins-LR (MC-LR) on autophagy in human neuroblastoma SK-N-SH cells.
Yang Y, Wen C, Zheng S, Liu W, Chen J, Feng X, Wang X, Yang F, Ding Z
Journal of toxicology and environmental health. Part A 2019;82(21):1129-1136
Journal of toxicology and environmental health. Part A 2019;82(21):1129-1136
Effects of microcystins-LR on genotoxic responses in human intestinal epithelial cells (NCM460).
Wen C, Zheng S, Yang Y, Li X, Chen J, Wang X, Feng X, Yang F
Journal of toxicology and environmental health. Part A 2019;82(21):1113-1119
Journal of toxicology and environmental health. Part A 2019;82(21):1113-1119
The role of miR-130a-3p and SPOCK1 in tobacco exposed bronchial epithelial BEAS-2B transformed cells: Comparison to A549 and H1299 lung cancer cell lines.
Yu XF, Wang J, OUYang N, Guo S, Sun H, Tong J, Chen T, Li J
Journal of toxicology and environmental health. Part A 2019;82(15):862-869
Journal of toxicology and environmental health. Part A 2019;82(15):862-869
Host factor SMYD3 is recruited by Ebola virus nucleoprotein to facilitate viral mRNA transcription.
Chen J, He Z, Yuan Y, Huang F, Luo B, Zhang J, Pan T, Zhang H, Zhang J
Emerging microbes & infections 2019;8(1):1347-1360
Emerging microbes & infections 2019;8(1):1347-1360
Decreased Amino Acid Concentrations are Involved in Congenital Heart Disease.
Lai G, Li X, Zhang B, Wang L, He R, Zhao Y
Annals of nutrition & metabolism 2019;74(3):257-263
Annals of nutrition & metabolism 2019;74(3):257-263
Targeting Pin1 by All-Trans Retinoic Acid (ATRA) Overcomes Tamoxifen Resistance in Breast Cancer via Multifactorial Mechanisms.
Huang S, Chen Y, Liang ZM, Li NN, Liu Y, Zhu Y, Liao D, Zhou XZ, Lu KP, Yao Y, Luo ML
Frontiers in cell and developmental biology 2019;7:322
Frontiers in cell and developmental biology 2019;7:322
Proteomic Profile of Carbonylated Proteins Screen the Regulation of Calmodulin-Dependent Protein Kinases-AMPK-Beclin1 in Aerobic Exercise-Induced Autophagy in Middle-Aged Rat Hippocampus.
Liu W, Xia Y, Kuang H, Wang Z, Liu S, Tang C, Yin D
Gerontology 2019;65(6):620-633
Gerontology 2019;65(6):620-633
miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways.
Feng X, Yan N, Sun W, Zheng S, Jiang S, Wang J, Guo C, Hao L, Tian Y, Liu S, Sun MZ
Cell death discovery 2019;5:89
Cell death discovery 2019;5:89
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
Zhang W, Yang Y, Gao H, Zhang Y, Jia Z, Huang S
Kidney & blood pressure research 2019;44(5):1002-1013
Kidney & blood pressure research 2019;44(5):1002-1013
MicroRNA-582-3p negatively regulates cell proliferation and cell cycle progression in acute myeloid leukemia by targeting cyclin B2.
Li H, Tian X, Wang P, Huang M, Xu R, Nie T
Cellular & molecular biology letters 2019;24:66
Cellular & molecular biology letters 2019;24:66
Down-regulation of miR-30b-5p protects cardiomyocytes against hypoxia-induced injury by targeting Aven.
Zhang L, Jia X
Cellular & molecular biology letters 2019;24:61
Cellular & molecular biology letters 2019;24:61
PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer.
Wang M, Gao Q, Chen Y, Li Z, Yue L, Cao Y
Cellular & molecular biology letters 2019;24:58
Cellular & molecular biology letters 2019;24:58
Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2.
Ban D, Hua S, Zhang W, Shen C, Miao X, Liu W
Cellular & molecular biology letters 2019;24:52
Cellular & molecular biology letters 2019;24:52
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Li W, Cao J, Liu J, Chu W, Zhang C, Chen S, Kang Z
Cellular & molecular biology letters 2019;24:19
Cellular & molecular biology letters 2019;24:19
Chaihu-Shugan-San Reinforces CYP3A4 Expression via Pregnane X Receptor in Depressive Treatment of Liver-Qi Stagnation Syndrome.
He Z, Fan R, Zhang C, Tang T, Liu X, Luo J, Cui H, Wang Y, Lu R, Gan P
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9781675
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9781675
Huangqi-Danshen Decoction Ameliorates Adenine-Induced Chronic Kidney Disease by Modulating Mitochondrial Dynamics.
Liu X, Huang S, Wang F, Zheng L, Lu J, Chen J, Li S
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9574045
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9574045
A Compound of Chinese Herbs Protects against Alcoholic Liver Fibrosis in Rats via the TGF-β1/Smad Signaling Pathway.
Li X, Liu Y, Yue W, Tan Y, Wang H, Zhang L, Chen J
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9121347
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9121347
Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression.
Chu Y, You M, Zhang J, Gao G, Han R, Luo W, Liu T, Zuo J, Wang F
Stem cells international 2019;2019:9037197
Stem cells international 2019;2019:9037197
Curcumin Inhibits Proliferation of Epstein-Barr Virus-Associated Human Nasopharyngeal Carcinoma Cells by Inhibiting EBV Nuclear Antigen 1 Expression.
Liu L, Yang J, Ji W, Wang C
BioMed research international 2019;2019:8592921
BioMed research international 2019;2019:8592921
Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes.
Jiang C, Xu J, Zhu W, Cai Y, Wang S, Guo Y, Xu K, Geng M, Hussain N, Han Y, Zhang F, Ning Q, Meng L, Lu S
Mediators of inflammation 2019;2019:6768504
Mediators of inflammation 2019;2019:6768504
Effect of Bufei Yishen Granules Combined with Electroacupuncture in Rats with Chronic Obstructive Pulmonary Disease via the Regulation of TLR-4/NF-κB Signaling.
Ma J, Tian Y, Li J, Zhang L, Wu M, Zhu L, Liu S
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6708645
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6708645
UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells.
Li C, Li L, Chen K, Wang Y, Yang F, Wang G
Oxidative medicine and cellular longevity 2019;2019:6505373
Oxidative medicine and cellular longevity 2019;2019:6505373
Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation.
Chai N, Zhang H, Li L, Yu X, Liu Y, Lin Y, Wang L, Yan J, Nikolaevna SE, Zhao Y
Oxidative medicine and cellular longevity 2019;2019:5406468
Oxidative medicine and cellular longevity 2019;2019:5406468
Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson's Disease Cell Models.
Wei PC, Lee-Chen GJ, Chen CM, Wu YR, Chen YJ, Lin JL, Lo YS, Yao CF, Chang KH
Oxidative medicine and cellular longevity 2019;2019:5074367
Oxidative medicine and cellular longevity 2019;2019:5074367
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Xu X, Zong Y, Gao Y, Sun X, Zhao H, Luo W, Jia S
BioMed research international 2019;2019:3909102
BioMed research international 2019;2019:3909102
Glu-mGluR2/3-ERK Signaling Regulates Apoptosis of Hippocampal Neurons in Diabetic-Depression Model Rats.
Liu Z, Han Y, Zhao H, Luo W, Jia L, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3710363
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3710363
Role of Cav-1 in HIV-1 Tat-Induced Dysfunction of Tight Junctions and Aβ-Transferring Proteins.
Zou M, Huang W, Jiang W, Wu Y, Chen Q
Oxidative medicine and cellular longevity 2019;2019:3403206
Oxidative medicine and cellular longevity 2019;2019:3403206
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
Ma Q, Gao Y, Xu P, Li K, Xu X, Gao J, Qi Y, Xu J, Yang Y, Song W, He X, Liu S, Yuan X, Yin W, He Y, Pan W, Wei L, Zhang J
BioMed research international 2019;2019:3235021
BioMed research international 2019;2019:3235021
SIRT7 Regulates Lipopolysaccharide-Induced Inflammatory Injury by Suppressing the NF-κB Signaling Pathway.
Chen KL, Li L, Li CM, Wang YR, Yang FX, Kuang MQ, Wang GL
Oxidative medicine and cellular longevity 2019;2019:3187972
Oxidative medicine and cellular longevity 2019;2019:3187972
Danggui Shaoyao San Ameliorates Renal Fibrosis via Regulation of Hypoxia and Autophagy.
Zhang MY, Chen HH, Tian J, Chen HJ, Zhu LL, Zhao P, Zhang T
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2985270
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2985270
Effect of Baoshenfang Formula on Podocyte Injury via Inhibiting the NOX-4/ROS/p38 Pathway in Diabetic Nephropathy.
Cui FQ, Tang L, Gao YB, Wang YF, Meng Y, Shen C, Shen ZL, Liu ZQ, Zhao WJ, Liu WJ
Journal of diabetes research 2019;2019:2981705
Journal of diabetes research 2019;2019:2981705
A Network Pharmacology Approach for Uncovering the Osteogenic Mechanisms of Psoralea corylifolia Linn.
Ge L, Cheng K, Han J
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2160175
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2160175
Neonatal Streptococcus pneumoniae Pneumonia Induces an Aberrant Airway Smooth Muscle Phenotype and AHR in Mice Model.
Peng X, Wu Y, Kong X, Chen Y, Tian Y, Li Q, Tian X, Zhang G, Ren L, Luo Z
BioMed research international 2019;2019:1948519
BioMed research international 2019;2019:1948519
Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.
Zhu HF, Zhang XH, Gu CS, Zhong Y, Long T, Ma YD, Hu ZY, Li ZG, Wang XY
Cancer biology & therapy 2019;20(7):967-978
Cancer biology & therapy 2019;20(7):967-978
LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells.
Wang X, Lan Z, He J, Lai Q, Yao X, Li Q, Liu Y, Lai H, Gu C, Yan Q, Fang Y, Zhang Y, Li A, Liu S
Cancer cell international 2019;19:234
Cancer cell international 2019;19:234
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways.
Jin Y, Li Y, Wang X, Yang Y
Cancer cell international 2019;19:220
Cancer cell international 2019;19:220
Circular RNA MYLK promotes hepatocellular carcinoma progression by increasing Rab23 expression by sponging miR-362-3p.
Li Z, Hu Y, Zeng Q, Wang H, Yan J, Li H, Yu Z
Cancer cell international 2019;19:211
Cancer cell international 2019;19:211
LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b.
Guo J, Li Y, Duan H, Yuan L
Cancer cell international 2019;19:156
Cancer cell international 2019;19:156
Proteomic analysis of human periodontal ligament cells under hypoxia.
Li Q, Luo T, Lu W, Yi X, Zhao Z, Liu J
Proteome science 2019;17:3
Proteome science 2019;17:3
The GLP-1 agonist, liraglutide, ameliorates inflammation through the activation of the PKA/CREB pathway in a rat model of knee osteoarthritis.
Que Q, Guo X, Zhan L, Chen S, Zhang Z, Ni X, Ye B, Wan S
Journal of inflammation (London, England) 2019;16:13
Journal of inflammation (London, England) 2019;16:13
BRD4 Inhibitor AZD5153 Suppresses the Proliferation of Colorectal Cancer Cells and Sensitizes the Anticancer Effect of PARP Inhibitor.
Zhang P, Li R, Xiao H, Liu W, Zeng X, Xie G, Yang W, Shi L, Yin Y, Tao K
International journal of biological sciences 2019;15(9):1942-1954
International journal of biological sciences 2019;15(9):1942-1954
Exosomes derived from Wharton's jelly of human umbilical cord mesenchymal stem cells reduce osteocyte apoptosis in glucocorticoid-induced osteonecrosis of the femoral head in rats via the miR-21-PTEN-AKT signalling pathway.
Kuang MJ, Huang Y, Zhao XG, Zhang R, Ma JX, Wang DC, Ma XL
International journal of biological sciences 2019;15(9):1861-1871
International journal of biological sciences 2019;15(9):1861-1871
Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers.
Chen CH, Yang N, Zhang Y, Ding J, Zhang W, Liu R, Liu W, Chen C
International journal of biological sciences 2019;15(8):1733-1742
International journal of biological sciences 2019;15(8):1733-1742
miR-155-5p Promotes Dorsal Root Ganglion Neuron Axonal Growth in an Inhibitory Microenvironment via the cAMP/PKA Pathway.
Wang T, Li B, Wang Z, Yuan X, Chen C, Zhang Y, Xia Z, Wang X, Yu M, Tao W, Zhang L, Wang X, Zhang Z, Guo X, Ning G, Feng S, Chen X
International journal of biological sciences 2019;15(7):1557-1570
International journal of biological sciences 2019;15(7):1557-1570
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
Ma S, Miao H, Luo Y, Sun Y, Tian X, Wang F, You C, Peng S, Tang G, Yang C, Sun W, Li S, Mao Y, Xu J, Xiao Y, Gong Y, Quan H, Xie C
International journal of biological sciences 2019;15(5):999-1009
International journal of biological sciences 2019;15(5):999-1009
FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6.
Dai X, Cheng H, Chen X, Li T, Zhang J, Jin G, Cai D, Huang Z
International journal of biological sciences 2019;15(5):1030-1041
International journal of biological sciences 2019;15(5):1030-1041
Macrophage Colony-stimulating Factor Mediates the Recruitment of Macrophages in Triple negative Breast Cancer.
Lu X, Yang R, Zhang L, Xi Y, Zhao J, Wang F, Zhang H, Li Z
International journal of biological sciences 2019;15(13):2859-2871
International journal of biological sciences 2019;15(13):2859-2871
CREB1/Lin28/miR-638/VASP Interactive Network Drives the Development of Breast Cancer.
Hu PC, Li K, Tian YH, Pan WT, Wang Y, Xu XL, He YQ, Gao Y, Wei L, Zhang JW
International journal of biological sciences 2019;15(12):2733-2749
International journal of biological sciences 2019;15(12):2733-2749
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.
Liu H, Zhao J, Fu R, Zhu C, Fan D
PloS one 2019;14(5):e0216759
PloS one 2019;14(5):e0216759
Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
Nishizawa K, Yoda N, Morokado F, Komori H, Nakanishi T, Tamai I
PloS one 2019;14(4):e0214862
PloS one 2019;14(4):e0214862
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Zhao Y, Zhang Y, Vazirinejad Mehdiabad M, Zhou K, Chen Y, Li L, Guo J, Xu C
PloS one 2019;14(10):e0223232
PloS one 2019;14(10):e0223232
Up-regulation of antioxidative proteins TRX1, TXNL1 and TXNRD1 in the cortex of PTZ kindling seizure model mice.
Yu JT, Liu Y, Dong P, Cheng RE, Ke SX, Chen KQ, Wang JJ, Shen ZS, Tang QY, Zhang Z
PloS one 2019;14(1):e0210670
PloS one 2019;14(1):e0210670
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
Sun Y, Gong J, Cao Y
International journal of nanomedicine 2019;14:9285-9294
International journal of nanomedicine 2019;14:9285-9294
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Tran BH, Yu Y, Chang L, Tan B, Jia W, Xiong Y, Dai T, Zhong R, Zhang W, Le VM, Rose P, Wang Z, Mao Y, Zhu YZ
International journal of nanomedicine 2019;14:10061-10077
International journal of nanomedicine 2019;14:10061-10077
Dexmedetomidine attenuates the neurotoxicity of propofol toward primary hippocampal neurons in vitro via Erk1/2/CREB/BDNF signaling pathways.
Tu Y, Liang Y, Xiao Y, Lv J, Guan R, Xiao F, Xie Y, Xiao Q
Drug design, development and therapy 2019;13:695-706
Drug design, development and therapy 2019;13:695-706
RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.
Guo Z, Tian Y, Guo Y, Li B, Liu X, Xie K, Song Y, Wang D
Frontiers in cellular neuroscience 2019;13:392
Frontiers in cellular neuroscience 2019;13:392
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Wang Y, Shao Y, Gao Y, Wan G, Wan D, Zhu H, Qiu Y, Ye X
Drug design, development and therapy 2019;13:243-253
Drug design, development and therapy 2019;13:243-253
Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats.
Wang X, Shan Y, Tang Z, Gao L, Liu H
Drug design, development and therapy 2019;13:153-160
Drug design, development and therapy 2019;13:153-160
Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.
Zhuang K, Zuo YC, Sherchan P, Wang JK, Yan XX, Liu F
Frontiers in neuroscience 2019;13:1441
Frontiers in neuroscience 2019;13:1441
Long Non-coding RNA KCNQ1OT1 Contributes to Antiepileptic Drug Resistance Through the miR-138-5p/ABCB1 Axis in vitro.
Xie Y, Wang M, Shao Y, Deng X, Chen Y
Frontiers in neuroscience 2019;13:1358
Frontiers in neuroscience 2019;13:1358
BAF45D Downregulation in Spinal Cord Ependymal Cells Following Spinal Cord Injury in Adult Rats and Its Potential Role in the Development of Neuronal Lesions.
Wang Z, Huang J, Liu C, Liu L, Shen Y, Shen C, Liu C
Frontiers in neuroscience 2019;13:1151
Frontiers in neuroscience 2019;13:1151
Key Genes And Pathways Controlled By E2F1 In Human Castration-Resistant Prostate Cancer Cells.
Zhou Q, Wang C, Zhu Y, Wu Q, Jiang Y, Huang Y, Hu Y
OncoTargets and therapy 2019;12:8961-8976
OncoTargets and therapy 2019;12:8961-8976
MiR-200a-3p promoted the malignant behaviors of ovarian cancer cells through regulating PCDH9.
Shi C, Yang Y, Zhang L, Yu J, Qin S, Xu H, Gao Y
OncoTargets and therapy 2019;12:8329-8338
OncoTargets and therapy 2019;12:8329-8338
Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.
Hu YH, Ma S, Zhang XN, Zhang ZY, Zhu HF, Ji YH, Li J, Qian XL, Wang YX
OncoTargets and therapy 2019;12:8105-8115
OncoTargets and therapy 2019;12:8105-8115
Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.
Guan H, Li J, Sun R, Liu W, Feng M, Ma H, Li C
OncoTargets and therapy 2019;12:7897-7909
OncoTargets and therapy 2019;12:7897-7909
Transcription factor E2F1 positively regulates interferon regulatory factor 5 expression in non-small cell lung cancer.
Feng DD, Cao Q, Zhang DQ, Wu XL, Yang CX, Chen YF, Yu T, Qi HX, Zhou GP
OncoTargets and therapy 2019;12:6907-6915
OncoTargets and therapy 2019;12:6907-6915
Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression.
Wang M, Xu Y, Wen GZ, Wang Q, Yuan SM
OncoTargets and therapy 2019;12:4643-4654
OncoTargets and therapy 2019;12:4643-4654
miR-29a inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting DPP4.
Wang Y, Han J, Lv Y, Zhang G
OncoTargets and therapy 2019;12:4225-4233
OncoTargets and therapy 2019;12:4225-4233
Prognostic significance and biological function of Lamina-associated polypeptide 2 in non-small-cell lung cancer.
Liu C, Yu H, Shen X, Qiao J, Wu X, Chang J, Zhu X, Wang J, Shen X
OncoTargets and therapy 2019;12:3817-3827
OncoTargets and therapy 2019;12:3817-3827
The reversal of MRP1 expression induced by low-frequency and low-intensity ultrasound and curcumin mediated by VEGF in brain glioma.
Yao L, Zhang Z
OncoTargets and therapy 2019;12:3581-3593
OncoTargets and therapy 2019;12:3581-3593
Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling.
Liu L, Li Y, Pan B, Zhang T, Wei D, Zhu Y, Guo Y
OncoTargets and therapy 2019;12:2891-2902
OncoTargets and therapy 2019;12:2891-2902
DEAD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells.
Yang C, Li D, Bai Y, Song S, Yan P, Wu R, Zhang Y, Hu G, Lin C, Li X, Huang L
OncoTargets and therapy 2019;12:233-241
OncoTargets and therapy 2019;12:233-241
Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin.
Dong C, Liu X, Wang H, Li J, Dai L, Li J, Xu Z
OncoTargets and therapy 2019;12:1947-1956
OncoTargets and therapy 2019;12:1947-1956
MACC1 promotes angiogenesis in cholangiocarcinoma by upregulating VEGFA.
Peng T, Li Z, Li D, Wang S
OncoTargets and therapy 2019;12:1893-1903
OncoTargets and therapy 2019;12:1893-1903
The overexpression of Rab9 promotes tumor progression regulated by XBP1 in breast cancer.
Liu Y, Wang X, Zhang Z, Xiao B, An B, Zhang J
OncoTargets and therapy 2019;12:1815-1824
OncoTargets and therapy 2019;12:1815-1824
Elevated HOXA13 expression promotes the proliferation and metastasis of gastric cancer partly via activating Erk1/2.
Qin Z, Chen Z, Weng J, Li S, Rong Z, Zhou C
OncoTargets and therapy 2019;12:1803-1813
OncoTargets and therapy 2019;12:1803-1813
LncRNA HOTAIRM1/HOXA1 Axis Promotes Cell Proliferation, Migration And Invasion In Endometrial Cancer.
Li X, Pang L, Yang Z, Liu J, Li W, Wang D
OncoTargets and therapy 2019;12:10997-11015
OncoTargets and therapy 2019;12:10997-11015
FAT4-USP51 complex regulates the proliferation and invasion of endometrial cancer via Hippo pathway.
Che X, Jian F, Jia N, Zheng Y, Jiang Y, Feng W
American journal of translational research 2019;11(5):2784-2800
American journal of translational research 2019;11(5):2784-2800
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
Zhu H, Wang Y, Yang X, Wan G, Qiu Y, Ye X, Gao Y, Wan D
American journal of translational research 2019;11(3):1311-1326
American journal of translational research 2019;11(3):1311-1326
AIF-1 and RNASET2 Play Complementary Roles in the Innate Immune Response of Medicinal Leech.
Baranzini N, Monti L, Vanotti M, Orlandi VT, Bolognese F, Scaldaferri D, Girardello R, Tettamanti G, de Eguileor M, Vizioli J, Taramelli R, Acquati F, Grimaldi A
Journal of innate immunity 2019;11(2):150-167
Journal of innate immunity 2019;11(2):150-167
Collagen prolyl 4-hydroxylase 2 predicts worse prognosis and promotes glycolysis in cervical cancer.
Li Q, Wang Q, Zhang Q, Zhang J, Zhang J
American journal of translational research 2019;11(11):6938-6951
American journal of translational research 2019;11(11):6938-6951
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, Song Y, Luo J
American journal of translational research 2019;11(10):6680-6690
American journal of translational research 2019;11(10):6680-6690
Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies.
Jiang J, Wang X, Gao G, Liu X, Chang H, Xiong R, Lu J, Sun Z
American journal of translational research 2019;11(10):6382-6392
American journal of translational research 2019;11(10):6382-6392
TINAGL1 promotes hepatocellular carcinogenesis through the activation of TGF-β signaling-medicated VEGF expression.
Sun L, Dong Z, Gu H, Guo Z, Yu Z
Cancer management and research 2019;11:767-775
Cancer management and research 2019;11:767-775
Disulfiram inhibits epithelial-mesenchymal transition through TGFβ-ERK-Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis.
Bu W, Wang Z, Meng L, Li X, Liu X, Chen Y, Xin Y, Li B, Sun H
Cancer management and research 2019;11:3887-3898
Cancer management and research 2019;11:3887-3898
lncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3β axis in hepatocellular carcinoma.
Wang F, Qi X, Li Z, Jin S, Xie Y, Zhong H
Cancer management and research 2019;11:3813-3828
Cancer management and research 2019;11:3813-3828
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Wang LY, Yu X, Li XX, Zhao YN, Wang CY, Wang ZY, He ZY
Frontiers in aging neuroscience 2019;11:316
Frontiers in aging neuroscience 2019;11:316
Synergistic cytotoxicity of homoharringtonine and etoposide in acute myeloid leukemia cells involves disrupted antioxidant defense.
Zhang J, Geng H, Liu L, Zhang H
Cancer management and research 2019;11:1023-1032
Cancer management and research 2019;11:1023-1032
LncRNA SNHG16 Functions as an Oncogene by Sponging MiR-135a and Promotes JAK2/STAT3 Signal Pathway in Gastric Cancer.
Wang X, Kan J, Han J, Zhang W, Bai L, Wu H
Journal of Cancer 2019;10(4):1013-1022
Journal of Cancer 2019;10(4):1013-1022
RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma.
Men W, Li W, Li Y, Zhao J, Qu X, Li P, Gong S
Journal of Cancer 2019;10(25):6278-6285
Journal of Cancer 2019;10(25):6278-6285
Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway.
Liang Y, Zhu D, Zhu L, Hou Y, Hou L, Huang X, Li L, Wang Y, Li L, Zou H, Wu T, Yao M, Wang J, Meng X
Journal of Cancer 2019;10(24):6037-6047
Journal of Cancer 2019;10(24):6037-6047
Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells.
He L, Wu MZ, Wang XB, Qiu XS, Wang EH, Wu GP
Journal of Cancer 2019;10(16):3632-3638
Journal of Cancer 2019;10(16):3632-3638
Dysregulation of MiR-519d Affects Oral Squamous Cell Carcinoma Invasion and Metastasis by Targeting MMP3.
Jin Y, Li Y, Wang X, Yang Y
Journal of Cancer 2019;10(12):2720-2734
Journal of Cancer 2019;10(12):2720-2734
CBX2 Regulates Proliferation and Apoptosis via the Phosphorylation of YAP in Hepatocellular Carcinoma.
Mao J, Tian Y, Wang C, Jiang K, Li R, Yao Y, Zhang R, Sun D, Liang R, Gao Z, Wang Q, Wang L
Journal of Cancer 2019;10(12):2706-2719
Journal of Cancer 2019;10(12):2706-2719
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
Gao Y, Chen Z, Wang R, Tan X, Huang C, Chen G, Chen Z
Journal of Cancer 2019;10(1):156-167
Journal of Cancer 2019;10(1):156-167
Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism.
Qiao X, Zhou ZC, Niu R, Su YT, Sun Y, Liu HL, Teng JL, Ye JN, Shi H, Yang CD, Cheng XB
Frontiers in pharmacology 2019;10:855
Frontiers in pharmacology 2019;10:855
Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values.
Doudou NR, Kampo S, Liu Y, Ahmmed B, Zeng D, Zheng M, Mohamadou A, Wen QP, Wang S
Frontiers in physiology 2019;10:708
Frontiers in physiology 2019;10:708
Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.
He J, Ding J, Lai Q, Wang X, Li A, Liu S
Frontiers in physiology 2019;10:681
Frontiers in physiology 2019;10:681
Improved FGF21 Sensitivity and Restored FGF21 Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats After Duodenal-Jejunal Bypass and Sleeve Gastrectomy.
Liu Q, Wang S, Wei M, Huang X, Cheng Y, Shao Y, Xia P, Zhong M, Liu S, Zhang G, Hu S
Frontiers in endocrinology 2019;10:566
Frontiers in endocrinology 2019;10:566
Hydroxytyrosol Improves Obesity and Insulin Resistance by Modulating Gut Microbiota in High-Fat Diet-Induced Obese Mice.
Liu Z, Wang N, Ma Y, Wen D
Frontiers in microbiology 2019;10:390
Frontiers in microbiology 2019;10:390
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
Xin S, Du S, Liu L, Xie Y, Zuo L, Yang J, Hu J, Yue W, Zhang J, Cao P, Zhu F, Lu J
Frontiers in microbiology 2019;10:2879
Frontiers in microbiology 2019;10:2879
NF-κB-Dependent IFIT3 Induction by HBx Promotes Hepatitis B Virus Replication.
Xu F, Song H, An B, Xiao Q, Cheng G, Tan G
Frontiers in microbiology 2019;10:2382
Frontiers in microbiology 2019;10:2382
Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells.
Zhou D, Zhuang J, Wang Y, Zhao D, Zhao L, Zhu S, Pu J, Yin M, Zhang H, Wang Z, Hong J
Frontiers in physiology 2019;10:223
Frontiers in physiology 2019;10:223
Lovastatin Inhibits HIV-1-Induced MHC-I Downregulation by Targeting Nef-AP-1 Complex Formation: A New Strategy to Boost Immune Eradication of HIV-1 Infected Cells.
Liu B, Zhang X, Zhang W, Wu L, Jing S, Liu W, Xia B, Zou F, Lu L, Ma X, He D, Hu Q, Zhang Y, Deng K, Cai W, Tang X, Peng T, Zhang H, Li L
Frontiers in immunology 2019;10:2151
Frontiers in immunology 2019;10:2151
IL-19 Up-Regulates Mucin 5AC Production in Patients With Chronic Rhinosinusitis via STAT3 Pathway.
Lai X, Li X, Chang L, Chen X, Huang Z, Bao H, Huang J, Yang L, Wu X, Wang Z, Bellanti JA, Zheng SG, Zhang G
Frontiers in immunology 2019;10:1682
Frontiers in immunology 2019;10:1682
Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5.
Gaspar RS, da Silva SA, Stapleton J, Fontelles JLL, Sousa HR, Chagas VT, Alsufyani S, Trostchansky A, Gibbins JM, Paes AMA
Frontiers in pharmacology 2019;10:1678
Frontiers in pharmacology 2019;10:1678
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
Maternal Nicotine Exposure During Gestation and Lactation Period Affects Behavior and Hippocampal Neurogenesis in Mouse Offspring.
Liu F, Tao X, Pang G, Wu D, Hu Y, Xue S, Liu J, Li B, Zhou L, Liu Q, Zhang YM
Frontiers in pharmacology 2019;10:1569
Frontiers in pharmacology 2019;10:1569
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, Jiang Y, Sun X, Li T, Cui L, Hu X
Frontiers in immunology 2019;10:1550
Frontiers in immunology 2019;10:1550
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Zhong Z, Qian Z, Zhang X, Chen F, Ni S, Kang Z, Zhang F, Li D, Yu B
Frontiers in pharmacology 2019;10:1530
Frontiers in pharmacology 2019;10:1530
Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis.
Dong L, Wu J, Chen K, Xie J, Wang Y, Li D, Liu Y, Yin A, Zhao Y, Han Y, Zhou J, Zhang L, Chen Z, Zuo D
Frontiers in immunology 2019;10:1239
Frontiers in immunology 2019;10:1239
FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response.
Dong L, Li R, Li D, Wang B, Lu Y, Li P, Yu F, Jin Y, Ni X, Wu Y, Yang S, Lv G, Li X, Xiao J, Wang J
Frontiers in pharmacology 2019;10:1224
Frontiers in pharmacology 2019;10:1224
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2019 Sep;93(9):2713
Archives of toxicology 2019 Sep;93(9):2713
Prazosin inhibits the growth and mobility of osteosarcoma cells.
An M, Ma WH, Jia HW, Li YW, Feng JJ, Meng J, Qi H, Liu J
Translational cancer research 2019 Sep;8(5):1997-2004
Translational cancer research 2019 Sep;8(5):1997-2004
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
Zhang X, Fang J, Chen S, Wang W, Meng S, Liu B
Cancer medicine 2019 Sep;8(12):5716-5734
Cancer medicine 2019 Sep;8(12):5716-5734
Protective effect of histone methyltransferase NSD3 on ISO-induced cardiac hypertrophy.
Chen K, Jian D, Zhao L, Zang X, Song W, Ma J, Jia Z, Wang X, Gao C
FEBS letters 2019 Sep;593(18):2556-2565
FEBS letters 2019 Sep;593(18):2556-2565
The interaction of LOXL2 with GATA6 induces VEGFA expression and angiogenesis in cholangiocarcinoma.
Peng T, Deng X, Tian F, Li Z, Jiang P, Zhao X, Chen G, Chen Y, Zheng P, Li D, Wang S
International journal of oncology 2019 Sep;55(3):657-670
International journal of oncology 2019 Sep;55(3):657-670
Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus.
Yang Q, Huang Z, Luo Y, Zheng F, Hu Y, Liu H, Zhu S, He M, Xu D, Li Y, Yang M, Yang Y, Wei X, Gao X, Wang W, Ma J, Ma Y, Wang X, Wang Q
EBioMedicine 2019 Sep;47:470-483
EBioMedicine 2019 Sep;47:470-483
Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis.
Yang Y, Du X, Wang Q, Liu J, Zhang E, Sai L, Peng C, Lavin MF, Yeo AJ, Yang X, Shao H, Du Z
International journal of molecular medicine 2019 Sep;44(3):903-912
International journal of molecular medicine 2019 Sep;44(3):903-912
Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis.
Sun Y, Pan W, Zhang J, Cui Y, Wang H, Ru G, Chen L
International journal of molecular medicine 2019 Sep;44(3):1106-1116
International journal of molecular medicine 2019 Sep;44(3):1106-1116
Tetramethylpyrazine downregulates transcription of the CXC receptor 4 (CXCR4) via nuclear respiratory factor‑1 (Nrf‑1) in WERI‑Rb1 retinoblastoma cells.
Wu N, Yang Y, Yu N, Wu Y, Han X, Chen S, Zhang J, Chen X, Wu C, Yang M, Qiu J, Ge J, Yu K, Zhuang J
Oncology reports 2019 Sep;42(3):1214-1224
Oncology reports 2019 Sep;42(3):1214-1224
Adjunctive Chinese herbal medicine therapy for nasopharyngeal carcinoma: Clinical evidence and experimental validation.
Song YC, Hung KF, Liang KL, Chiang JH, Huang HC, Lee HJ, Wu MY, Yu SJ, Lo HY, Ho TY, Yen HR
Head & neck 2019 Sep;41(9):2860-2872
Head & neck 2019 Sep;41(9):2860-2872
Comparison of Pregnane X Receptor Antagonists for Enhancing the Antitumor Effect of Cisplatin.
Yasuda M, Kishimoto S, Amano M, Fukushima S
Anticancer research 2019 Sep;39(9):4749-4755
Anticancer research 2019 Sep;39(9):4749-4755
Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model.
Wang S, Wang N, Yu B, Cao M, Wang Y, Guo Y, Zhang Y, Zhang P, Yu X, Wang S, Zeng L, Liang B, Li X, Wu Y
Oncogene 2019 Sep;38(36):6338-6353
Oncogene 2019 Sep;38(36):6338-6353
miR-15a-3p Suppresses Prostate Cancer Cell Proliferation and Invasion by Targeting SLC39A7 Via Downregulating Wnt/β-Catenin Signaling Pathway.
Cui Y, Yang Y, Ren L, Yang J, Wang B, Xing T, Chen H, Chen M
Cancer biotherapy & radiopharmaceuticals 2019 Sep;34(7):472-479
Cancer biotherapy & radiopharmaceuticals 2019 Sep;34(7):472-479
Two distinct E3 ligases, SCF(FBXL19) and HECW1, degrade thyroid transcription factor 1 in normal thyroid epithelial and follicular thyroid carcinoma cells, respectively.
Liu J, Dong S, Wang H, Li L, Ye Q, Li Y, Miao J, Jhiang S, Zhao J, Zhao Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10538-10550
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10538-10550
In vitro photodynamic therapy of endothelial cells using hematoporphyrin monomethyl ether (Hemoporfin): Relevance to treatment of port wine stains.
Mei Y, Xiao X, Fan L, Liu Q, Zheng M, Hamblin MR, Ni B, Yin R
Photodiagnosis and photodynamic therapy 2019 Sep;27:268-275
Photodiagnosis and photodynamic therapy 2019 Sep;27:268-275
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Wu G, Chen Z, Wang P, Zhao M, Fujino M, Zhang C, Zhou W, Hirano SI, Li XK, Zhao L
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Ding XF, Liang HY, Sun JY, Liu SH, Kan QC, Wang LX, Sun TW
Journal of cellular physiology 2019 Sep;234(9):16582-16591
Journal of cellular physiology 2019 Sep;234(9):16582-16591
Overexpression of oncostatin M receptor regulates local immune response in glioblastoma.
Guo Q, Guan GF, Cao JY, Zou CY, Zhu C, Cheng W, Xu XY, Lin ZG, Cheng P, Wu AH
Journal of cellular physiology 2019 Sep;234(9):15496-15509
Journal of cellular physiology 2019 Sep;234(9):15496-15509
Exogenous IL-19 mediates downregulation of TGF-β through Erk and p38 pathway to inhibit epidural fibrosis.
Wang QJ, Zhang AL, Kang ZQ, Zhang ZT, Wang YS
European review for medical and pharmacological sciences 2019 Sep;23(17):7184-7190
European review for medical and pharmacological sciences 2019 Sep;23(17):7184-7190
Localization of amyloid beta peptides to locus coeruleus and medial prefrontal cortex in corticotropin releasing factor overexpressing male and female mice.
Ross JA, Alexis R, Reyes BAS, Risbrough V, Van Bockstaele EJ
Brain structure & function 2019 Sep;224(7):2385-2405
Brain structure & function 2019 Sep;224(7):2385-2405
Human TIGIT on porcine aortic endothelial cells suppresses xenogeneic macrophage-mediated cytotoxicity.
Noguchi Y, Maeda A, Lo PC, Takakura C, Haneda T, Kodama T, Yoneyama T, Toyama C, Tazuke Y, Okuyama H, Miyagawa S
Immunobiology 2019 Sep;224(5):605-613
Immunobiology 2019 Sep;224(5):605-613
FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.
Fulcher LJ, He Z, Mei L, Macartney TJ, Wood NT, Prescott AR, Whigham AJ, Varghese J, Gourlay R, Ball G, Clarke R, Campbell DG, Maxwell CA, Sapkota GP
EMBO reports 2019 Sep;20(9):e47495
EMBO reports 2019 Sep;20(9):e47495
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
Zhang X, Bu H, Jiang Y, Sun G, Jiang R, Huang X, Duan H, Huang Z, Wu Q
Molecular medicine reports 2019 Sep;20(3):2867-2874
Molecular medicine reports 2019 Sep;20(3):2867-2874
MicroRNA‑671‑3p regulates the development of knee osteoarthritis by targeting TRAF3 in chondrocytes.
Liu Z, Chen S, Yang Y, Lu S, Zhao X, Hu B, Pei H
Molecular medicine reports 2019 Sep;20(3):2843-2850
Molecular medicine reports 2019 Sep;20(3):2843-2850
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091
Oncology letters 2019 Sep;18(3):3081-3091
Sodium ferulate attenuates high-glucose-induced oxidative injury in HT22 hippocampal cells.
Zhao J, Liu L, Zhang L, Lv J, Guo X, Li X, Zhao T
Experimental and therapeutic medicine 2019 Sep;18(3):2015-2020
Experimental and therapeutic medicine 2019 Sep;18(3):2015-2020
Hydroxytyrosol prevents PM(2.5)-induced adiposity and insulin resistance by restraining oxidative stress related NF-κB pathway and modulation of gut microbiota in a murine model.
Wang N, Ma Y, Liu Z, Liu L, Yang K, Wei Y, Liu Y, Chen X, Sun X, Wen D
Free radical biology & medicine 2019 Sep;141:393-407
Free radical biology & medicine 2019 Sep;141:393-407
The balance of apoptosis and autophagy via regulation of the AMPK signal pathway in aging rat striatum during regular aerobic exercise.
Liu W, Wang Z, Xia Y, Kuang H, Liu S, Li L, Tang C, Yin D
Experimental gerontology 2019 Sep;124:110647
Experimental gerontology 2019 Sep;124:110647
Long noncoding RNA H19 promotes chemotherapy resistance in choriocarcinoma cells.
Yu S, Wu C, Tan Q, Liu H
Journal of cellular biochemistry 2019 Sep;120(9):15131-15144
Journal of cellular biochemistry 2019 Sep;120(9):15131-15144
Methyl helicterate inhibits hepatic stellate cell activation through downregulating the ERK1/2 signaling pathway.
Wei Y, Zhang X, Wen S, Huang S, Huang Q, Lu S, Bai F, Nie J, Wei J, Lu Z, Lin X
Journal of cellular biochemistry 2019 Sep;120(9):14936-14945
Journal of cellular biochemistry 2019 Sep;120(9):14936-14945
Novel synthetic tosyl chloride-berbamine regresses lethal MYC-positive leukemia by targeting CaMKIIγ/Myc axis.
Yu Q, Wang P, Yang L, Wu Z, Li S, Xu Y, Wu B, Ma A, Gan X, Xu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109134
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109134
Huaier extract enhances the treatment efficacy of imatinib in Ik6(+) Ph(+) acute lymphoblastic leukemia.
Qu P, Han J, Qiu Y, Yu H, Hao J, Jin R, Zhou F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109071
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109071
Prolyl hydroxylase 3 involvement in lung cancer progression under hypoxic conditions: association with hypoxia-inducible factor-1α and pyruvate kinase M2.
Chu X, Xiang M, Feng L, Liu H, Zhou C
Journal of thoracic disease 2019 Sep;11(9):3941-3950
Journal of thoracic disease 2019 Sep;11(9):3941-3950
Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC.
Zuo L, Xie Y, Tang J, Xin S, Liu L, Zhang S, Yan Q, Zhu F, Lu J
Molecular therapy. Nucleic acids 2019 Sep 6;17:175-184
Molecular therapy. Nucleic acids 2019 Sep 6;17:175-184
STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1.
Wang H, Yuan M, Wang S, Zhang L, Zhang R, Zou X, Wang X, Chen D, Wu Z
International journal of molecular sciences 2019 Sep 30;20(19)
International journal of molecular sciences 2019 Sep 30;20(19)
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Zhang H, Tian X, Lu X, Xu D, Guo Y, Dong Z, Li Y, Ma Y, Chen C, Yang Y, Yang M, Yang Y, Liu F, Zhou R, He M, Xiao F, Wang X
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
Curcumin suppresses osteogenesis by inducing miR-126a-3p and subsequently suppressing the WNT/LRP6 pathway.
Li H, Yue L, Xu H, Li N, Li J, Zhang Z, Zhao RC
Aging 2019 Sep 3;11(17):6983-6998
Aging 2019 Sep 3;11(17):6983-6998
Optical control of protein phosphatase function.
Courtney TM, Deiters A
Nature communications 2019 Sep 26;10(1):4384
Nature communications 2019 Sep 26;10(1):4384
Citreoviridin induces myocardial apoptosis through PPAR-γ-mTORC2-mediated autophagic pathway and the protective effect of thiamine and selenium.
Feng C, Li D, Chen M, Jiang L, Liu X, Li Q, Geng C, Sun X, Yang G, Zhang L, Yao X
Chemico-biological interactions 2019 Sep 25;311:108795
Chemico-biological interactions 2019 Sep 25;311:108795
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Xu X, Chen X, Xu M, Liu X, Pan B, Qin J, Xu T, Zeng K, Pan Y, He B, Sun H, Sun L, Wang S
Aging 2019 Sep 22;11(18):7357-7385
Aging 2019 Sep 22;11(18):7357-7385
Neuroprotective effects of an Nrf2 agonist on high glucose-induced damage in HT22 cells.
Zhao J, Liu L, Li X, Zhang L, Lv J, Guo X, Chen H, Zhao T
Biological research 2019 Sep 21;52(1):53
Biological research 2019 Sep 21;52(1):53
Adenosine deaminase acting on RNA-1 (ADAR1) inhibits hepatitis B virus (HBV) replication by enhancing microRNA-122 processing.
Liu G, Ma X, Wang Z, Wakae K, Yuan Y, He Z, Yoshiyama H, Iizasa H, Zhang H, Matsuda M, Sugiyama R, Yuan Z, Muramatsu M, Li L
The Journal of biological chemistry 2019 Sep 20;294(38):14043-14054
The Journal of biological chemistry 2019 Sep 20;294(38):14043-14054
The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice.
Lin F, Yang D, Huang Y, Zhao Y, Ye J, Xiao M
Marine drugs 2019 Sep 20;17(10)
Marine drugs 2019 Sep 20;17(10)
RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21.
Liu G, Zhang Q, Xia L, Shi M, Cai J, Zhang H, Li J, Lin G, Xie W, Zhang Y, Xu N
Cell death & disease 2019 Sep 18;10(10):688
Cell death & disease 2019 Sep 18;10(10):688
Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma.
Zhong B, Shi D, Wu F, Wang S, Hu H, Cheng C, Qing X, Huang X, Luo X, Zhang Z, Shao Z
Cell death & disease 2019 Sep 18;10(10):687
Cell death & disease 2019 Sep 18;10(10):687
Cypermethrin exposure reduces the ovarian reserve by causing mitochondrial dysfunction in granulosa cells.
Wang H, He Y, Cheng D, Pu D, Tan R, Gao L, Cui Y, Wu J
Toxicology and applied pharmacology 2019 Sep 15;379:114693
Toxicology and applied pharmacology 2019 Sep 15;379:114693
Icariin protects rotenone-induced neurotoxicity through induction of SIRT3.
Zeng R, Wang X, Zhou Q, Fu X, Wu Q, Lu Y, Shi J, Klaunig JE, Zhou S
Toxicology and applied pharmacology 2019 Sep 15;379:114639
Toxicology and applied pharmacology 2019 Sep 15;379:114639
Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement.
Wu H, Chen H, Zheng Z, Li J, Ding J, Huang Z, Jia C, Shen Z, Bao G, Wu L, Mamun AA, Xu H, Gao W, Zhou K
Cell death & disease 2019 Sep 15;10(7):483
Cell death & disease 2019 Sep 15;10(7):483
MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model.
Yang J, Zhang L, Cao LL, Qi J, Li P, Wang XP, Sun XL
Cells 2019 Sep 13;8(9)
Cells 2019 Sep 13;8(9)
A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence.
Shen Z, Wang G, Yang Y, Shi J, Fang L, Li F, Xiao S, Fu ZF, Peng G
The Journal of biological chemistry 2019 Sep 13;294(37):13606-13618
The Journal of biological chemistry 2019 Sep 13;294(37):13606-13618
lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells.
Li Q, Zhang J, Su DM, Guan LN, Mu WH, Yu M, Ma X, Yang RJ
Human genomics 2019 Sep 13;13(1):50
Human genomics 2019 Sep 13;13(1):50
Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer.
Fu Z, Lin L, Liu S, Qin M, He S, Zhu L, Huang J
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 11;25:6836-6845
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 11;25:6836-6845
Minocycline Preserves the Integrity and Permeability of BBB by Altering the Activity of DKK1-Wnt Signaling in ICH Model.
Wang G, Li Z, Li S, Ren J, Suresh V, Xu D, Zang W, Liu X, Li W, Wang H, Guo F
Neuroscience 2019 Sep 1;415:135-146
Neuroscience 2019 Sep 1;415:135-146
Effects of PPARs/20-HETE on the renal impairment under diabetic conditions.
Ding S, Huang J, Qiu H, Chen R, Zhang J, Huang B, Cheng O, Jiang Q
Experimental cell research 2019 Sep 1;382(1):111455
Experimental cell research 2019 Sep 1;382(1):111455
Multiple functional therapeutic effects of DL-3-n-butylphthalide in the cuprizone model of demyelination.
Wu Y, Dong L, Huang Q, Sun L, Liao Y, Tang Y, Wu Y
Life sciences 2019 Sep 1;232:116501
Life sciences 2019 Sep 1;232:116501
Angiogenin promotes colorectal cancer metastasis via tiRNA production.
Li S, Shi X, Chen M, Xu N, Sun D, Bai R, Chen H, Ding K, Sheng J, Xu Z
International journal of cancer 2019 Sep 1;145(5):1395-1407
International journal of cancer 2019 Sep 1;145(5):1395-1407
The dietary freeze-dried fruit powder of Actinidia arguta ameliorates dextran sulphate sodium-induced ulcerative colitis in mice by inhibiting the activation of MAPKs.
Lian L, Zhang S, Yu Z, Ge H, Qi S, Zhang X, Long L, Xiong X, Chu D, Ma X, Li X, Gao H
Food & function 2019 Sep 1;10(9):5768-5778
Food & function 2019 Sep 1;10(9):5768-5778
Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats.
Liang M, Li H, Wang Z, Cai L, Yang L
Journal of the science of food and agriculture 2019 Oct;99(13):6097-6107
Journal of the science of food and agriculture 2019 Oct;99(13):6097-6107
PD-L1 over-expression is driven by B-cell receptor signaling in diffuse large B-cell lymphoma.
Wang WG, Jiang XN, Sheng D, Sun CB, Lee J, Zhou XY, Li XQ
Laboratory investigation; a journal of technical methods and pathology 2019 Oct;99(10):1418-1427
Laboratory investigation; a journal of technical methods and pathology 2019 Oct;99(10):1418-1427
Hexokinase 2 dimerization and interaction with voltage-dependent anion channel promoted resistance to cell apoptosis induced by gemcitabine in pancreatic cancer.
Fan K, Fan Z, Cheng H, Huang Q, Yang C, Jin K, Luo G, Yu X, Liu C
Cancer medicine 2019 Oct;8(13):5903-5915
Cancer medicine 2019 Oct;8(13):5903-5915
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Chen Y, Chen JQ, Ge MM, Zhang Q, Wang XQ, Zhu JY, Xie CF, Li XT, Zhong CY, Han HY
The Journal of nutritional biochemistry 2019 Oct;72:108219
The Journal of nutritional biochemistry 2019 Oct;72:108219
Targeting PLIN2/PLIN5-PPARγ: Sulforaphane Disturbs the Maturation of Lipid Droplets.
Tian S, Lei P, Teng C, Sun Y, Song X, Li B, Shan Y
Molecular nutrition & food research 2019 Oct;63(20):e1900183
Molecular nutrition & food research 2019 Oct;63(20):e1900183
Deciphering the multicomponent synergy mechanisms of SiNiSan prescription on irritable bowel syndrome using a bioinformatics/network topology based strategy.
Li B, Rui J, Ding X, Chen Y, Yang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Oct;63:152982
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Oct;63:152982
Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing.
Chen L, Ma MY, Sun M, Jiang LY, Zhao XT, Fang XX, Man Lam S, Shui GH, Luo J, Shi XJ, Song BL
Journal of lipid research 2019 Oct;60(10):1765-1775
Journal of lipid research 2019 Oct;60(10):1765-1775
The Hypermethylation of Foxp3 Promoter Impairs the Function of Treg Cells in EAP.
Chen J, Zhan C, Zhang L, Zhang L, Liu Y, Zhang Y, Du H, Liang C, Chen X
Inflammation 2019 Oct;42(5):1705-1718
Inflammation 2019 Oct;42(5):1705-1718
Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats.
Li PJ, Guo YQ, Ding PY, Liu RB, Deng F, Feng XX, Yan WJ
Neurological research 2019 Oct;41(10):867-874
Neurological research 2019 Oct;41(10):867-874
Leucine attenuates muscle atrophy and autophagosome formation by activating PI3K/AKT/mTOR signaling pathway in rotator cuff tears.
Zheng R, Huang S, Zhu J, Lin W, Xu H, Zheng X
Cell and tissue research 2019 Oct;378(1):113-125
Cell and tissue research 2019 Oct;378(1):113-125
Circular HDAC9/microRNA-138/Sirtuin-1 Pathway Mediates Synaptic and Amyloid Precursor Protein Processing Deficits in Alzheimer's Disease.
Lu Y, Tan L, Wang X
Neuroscience bulletin 2019 Oct;35(5):877-888
Neuroscience bulletin 2019 Oct;35(5):877-888
Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers.
Wang D, Hu X, Liu C, Jia Y, Bai Y, Cai C, Wang J, Bai L, Yang R, Lin C, Liu YR, Li S, Qiao F, Yao L, Chen L, Ge G, Jiang H, Li D, Li L, Chen J, Shao ZM, Zeng YA
Cell research 2019 Oct;29(10):832-845
Cell research 2019 Oct;29(10):832-845
BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells.
Hou Y, Fu J, Sun S, Jin Y, Wang X, Zhang L
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:429-438
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:429-438
Targeting miR-106-3p facilitates functional recovery via inactivating inflammatory microglia and interfering glial scar component deposition after neural injury.
Yang YH, Zhu J
European review for medical and pharmacological sciences 2019 Oct;23(20):9000-9008
European review for medical and pharmacological sciences 2019 Oct;23(20):9000-9008
A novel oncogene TRIM63 promotes cell proliferation and migration via activating Wnt/β-catenin signaling pathway in breast cancer.
Li K, Pan W, Ma Y, Xu X, Gao Y, He Y, Wei L, Zhang J
Pathology, research and practice 2019 Oct;215(10):152573
Pathology, research and practice 2019 Oct;215(10):152573
Downregulation of thymopoietin by miR-139-5p suppresses cell proliferation and induces cell cycle arrest/apoptosis in pancreatic ductal adenocarcinoma.
Zhou H, Zhang L, Tu H
Oncology letters 2019 Oct;18(4):3443-3452
Oncology letters 2019 Oct;18(4):3443-3452
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Gao X, Zhang Y, Zhang R, Zhao Z, Zhang H, Wu J, Shen W, Zhong M
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Circadian oscillations persist in low malignancy breast cancer cells.
Lellupitiyage Don SS, Lin HH, Furtado JJ, Qraitem M, Taylor SR, Farkas ME
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2447-2453
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2447-2453
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Biochemical pharmacology 2019 Oct;168:438-451
Biochemical pharmacology 2019 Oct;168:438-451
CX-F9, a novel RSK2 inhibitor, suppresses cutaneous melanoma cells proliferation and metastasis through regulating autophagy.
Zhang X, Cai L, Zhao S, Long J, Li J, Wu L, Su J, Zhang J, Tao J, Zhou J, Chen X, Peng C
Biochemical pharmacology 2019 Oct;168:14-25
Biochemical pharmacology 2019 Oct;168:14-25
Wnt7a, frequently silenced by CpG methylation, inhibits tumor growth and metastasis via suppressing epithelial-mesenchymal transition in gastric cancer.
Liu Y, Qiao Y, Zhang H, Li W, Zheng J
Journal of cellular biochemistry 2019 Oct;120(10):18142-18151
Journal of cellular biochemistry 2019 Oct;120(10):18142-18151
Identification of reciprocal microRNA-mRNA pairs associated with metastatic potential disparities in human prostate cancer cells and signaling pathway analysis.
Ma H, Wang LY, Yang RH, Zhou Y, Zhou P, Kong L
Journal of cellular biochemistry 2019 Oct;120(10):17779-17790
Journal of cellular biochemistry 2019 Oct;120(10):17779-17790
Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis.
Challa TD, Wueest S, Lucchini FC, Dedual M, Modica S, Borsigova M, Wolfrum C, Blüher M, Konrad D
EMBO molecular medicine 2019 Oct;11(10):e10124
EMBO molecular medicine 2019 Oct;11(10):e10124
Low-dose suspended graphene oxide nanosheets induce antioxidant response and osteogenic differentiation of bone marrow-derived mesenchymal stem cells via JNK-dependent FoxO1 activation.
Halim A, Liu L, Ariyanti AD, Ju Y, Luo Q, Song G
Journal of materials chemistry. B 2019 Oct 9;7(39):5998-6009
Journal of materials chemistry. B 2019 Oct 9;7(39):5998-6009
Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences.
Zhou Q, Xiao Q, Zhang Y, Wang X, Xiao Y, Shi D
Scientific reports 2019 Oct 29;9(1):15564
Scientific reports 2019 Oct 29;9(1):15564
Progesterone promotes embryo adhesion by upregulating c-Fos/c-Jun transcription factor-mediated poFUT1 expression†.
Cui X, Sun J, Liang C, Zheng Q, Yang X, Liu S, Yan Q
Biology of reproduction 2019 Oct 25;101(4):675-685
Biology of reproduction 2019 Oct 25;101(4):675-685
ACTL6A regulates follicle-stimulating hormone-driven glycolysis in ovarian cancer cells via PGK1.
Zhang J, Zhang J, Wei Y, Li Q, Wang Q
Cell death & disease 2019 Oct 24;10(11):811
Cell death & disease 2019 Oct 24;10(11):811
SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells.
Li J, Li N, Chen Y, Hui S, Fan J, Ye B, Fan Z, Zhang J, Zhao RC, Zhuang Q
Cell death & disease 2019 Oct 23;10(11):805
Cell death & disease 2019 Oct 23;10(11):805
Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells.
Hu B, Song W, Tang Y, Shi M, Li H, Yu D
Animals : an open access journal from MDPI 2019 Oct 21;9(10)
Animals : an open access journal from MDPI 2019 Oct 21;9(10)
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
Huang H, Fan Y, Gao Z, Wang W, Shao N, Zhang L, Yang Y, Zhu W, Chen Z, Hu J, Ding G
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
N(6)-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.
Chen RX, Chen X, Xia LP, Zhang JX, Pan ZZ, Ma XD, Han K, Chen JW, Judde JG, Deas O, Wang F, Ma NF, Guan X, Yun JP, Wang FW, Xu RH, Dan Xie
Nature communications 2019 Oct 16;10(1):4695
Nature communications 2019 Oct 16;10(1):4695
Trans-cinnamaldehyde shows anti-depression effect in the forced swimming test and possible involvement of the endocannabinoid system.
Lin J, Song Z, Chen X, Zhao R, Chen J, Chen H, Yang X, Wu Z
Biochemical and biophysical research communications 2019 Oct 15;518(2):351-356
Biochemical and biophysical research communications 2019 Oct 15;518(2):351-356
MiR-141-3p regulates proliferation and senescence of stem cells from apical papilla by targeting YAP.
Li Z, Ge X, Lu J, Bian M, Li N, Wu X, Li Y, Yan M, Yu J
Experimental cell research 2019 Oct 15;383(2):111562
Experimental cell research 2019 Oct 15;383(2):111562
Down-regulation of MARCO associates with tumor progression in hepatocellular carcinoma.
Xiao Y, Chen B, Yang K, Wang Q, Liu P, Gu Y, Zhong Q, Liu Z, He Y, Liu Q
Experimental cell research 2019 Oct 15;383(2):111542
Experimental cell research 2019 Oct 15;383(2):111542
Arsenic trioxide inhibits angiogenesis in vitro and in vivo by upregulating FoxO3a.
Sun Z, Li M, Bai L, Fu J, Lu J, Wu M, Zhou C, Zhang Y, Wu Y
Toxicology letters 2019 Oct 15;315:1-8
Toxicology letters 2019 Oct 15;315:1-8
Progranulin Decreases Susceptibility to Streptococcus pneumoniae in Influenza and Protects against Lethal Coinfection.
Wang X, Yuan J, Wang H, Gan N, Zhang Q, Liu B, Wang J, Shu Z, Rao L, Gou X, Zhang H, Yin Y, Zhang X
Journal of immunology (Baltimore, Md. : 1950) 2019 Oct 15;203(8):2171-2182
Journal of immunology (Baltimore, Md. : 1950) 2019 Oct 15;203(8):2171-2182
Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.
Li F, Zhang Y, Lu X, Shi J, Gong Q
Life sciences 2019 Oct 1;234:116739
Life sciences 2019 Oct 1;234:116739
A one-step specific assay for continuous detection of sirtuin 2 activity.
Dai Q, Zheng Z, Xia F, Liu P, Li M
Acta pharmaceutica Sinica. B 2019 Nov;9(6):1183-1192
Acta pharmaceutica Sinica. B 2019 Nov;9(6):1183-1192
Interleukin-6: Its role and mechanisms in rescuing depression-like behaviors in rat models of depression.
Wang P, Feng YB, Wang L, Li Y, Fan C, Song Q, Yu SY
Brain, behavior, and immunity 2019 Nov;82:106-121
Brain, behavior, and immunity 2019 Nov;82:106-121
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
Fan J, Wang Q, Zhang Z, Sun L
Drug development research 2019 Nov;80(7):992-999
Drug development research 2019 Nov;80(7):992-999
Caveolin-1 promotes Rfng expression via Erk-Jnk-p38 signaling pathway in mouse hepatocarcinoma cells.
Zhang C, Wu Q, Huang H, Chen X, Huang T, Li W, Liu Y, Zhang J
Journal of physiology and biochemistry 2019 Nov;75(4):549-559
Journal of physiology and biochemistry 2019 Nov;75(4):549-559
GLI1 is increased in ovarian endometriosis and regulates migration, invasion and proliferation of human endometrial stromal cells in endometriosis.
Liu H, Zhang W, Wang L, Zhang Z, Xiong W, Zhang L, Fu T, Li X, Chen Y, Liu Y
Annals of translational medicine 2019 Nov;7(22):663
Annals of translational medicine 2019 Nov;7(22):663
Melatonin/PGC1A/UCP1 promotes tumor slimming and represses tumor progression by initiating autophagy and lipid browning.
Xiao W, Xiong Z, Xiong W, Yuan C, Xiao H, Ruan H, Song Z, Wang C, Bao L, Cao Q, Wang K, Cheng G, Xu T, Tong J, Zhou L, Hu W, Ru Z, Liu D, Yang H, Zhang X, Chen K
Journal of pineal research 2019 Nov;67(4):e12607
Journal of pineal research 2019 Nov;67(4):e12607
Long non-coding RNA MYOSLID functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-29c-3p in gastric cancer.
Han Y, Wu N, Jiang M, Chu Y, Wang Z, Liu H, Cao J, Liu H, Xu B, Xie X
Cell proliferation 2019 Nov;52(6):e12678
Cell proliferation 2019 Nov;52(6):e12678
5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-x(L).
Shi T, Gao M, He M, Yue F, Zhao Y, Sun M, He K, Chen L
Molecular and cellular biochemistry 2019 Nov;461(1-2):151-158
Molecular and cellular biochemistry 2019 Nov;461(1-2):151-158
Quantitative proteomics reveal the alterations in the spinal cord after myocardial ischemia‑reperfusion injury in rats.
Li SY, Li ZX, He ZG, Wang Q, Li YJ, Yang Q, Wu DZ, Zeng HL, Xiang HB
International journal of molecular medicine 2019 Nov;44(5):1877-1887
International journal of molecular medicine 2019 Nov;44(5):1877-1887
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Wang Z, Zhang M, Shan R, Wang YJ, Chen J, Huang J, Sun LQ, Zhou WB
Oncology reports 2019 Nov;42(5):1915-1923
Oncology reports 2019 Nov;42(5):1915-1923
MicroRNA‑203a‑3p is a candidate tumor suppressor that targets thrombospondin 2 in colorectal carcinoma.
Qian Z, Gong L, Mou Y, Han Y, Zheng S
Oncology reports 2019 Nov;42(5):1825-1832
Oncology reports 2019 Nov;42(5):1825-1832
BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis.
Yuan YM, Ma N, Zhang EB, Chen TW, Jiang H, Yin FF, Wang JJ, Zhang FK, Ni QZ, Wang X, Bao Y, Wang K, Cheng SQ, Zhang XL, Wang XF, Li JJ, Xie D
Oncogene 2019 Nov;38(48):7281-7293
Oncogene 2019 Nov;38(48):7281-7293
Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism.
Yap JLY, Tai YK, Fröhlich J, Fong CHH, Yin JN, Foo ZL, Ramanan S, Beyer C, Toh SJ, Casarosa M, Bharathy N, Kala MP, Egli M, Taneja R, Lee CN, Franco-Obregón A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12853-12872
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12853-12872
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
Cheng X, Tan S, Duan F, Yuan Q, Li Q, Deng G
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation.
Liu Q, Zhang S, Sun Z, Guo X, Zhou H
Cell death and differentiation 2019 Nov;26(11):2386-2399
Cell death and differentiation 2019 Nov;26(11):2386-2399
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
Kuang M, Li L, Li C, Wang G
Cell stress & chaperones 2019 Nov;24(6):1115-1125
Cell stress & chaperones 2019 Nov;24(6):1115-1125
NOD2 agonist murabutide alleviates radiation-induced injury through DNA damage response pathway mediated by ATR.
Liu L, Qu H, Qin H, Yang Y, Liao Z, Cui J, Gao F, Cai J
Journal of cellular physiology 2019 Nov;234(11):21294-21306
Journal of cellular physiology 2019 Nov;234(11):21294-21306
GRP94 promotes muscle differentiation by inhibiting the PI3K/AKT/mTOR signaling pathway.
Li S, Fu Y, Pang Y, Tong H, Li S, Yan Y
Journal of cellular physiology 2019 Nov;234(11):21211-21223
Journal of cellular physiology 2019 Nov;234(11):21211-21223
MicroRNA-507 represses the malignant behaviors of non-small cell lung cancer via targeting zinc finger E-box binding homeobox 2.
Lv HL, Li ZL, Song YB
European review for medical and pharmacological sciences 2019 Nov;23(22):9955-9964
European review for medical and pharmacological sciences 2019 Nov;23(22):9955-9964
Aspirin inhibits adipogenesis of tendon stem cells and lipids accumulation in rat injury tendon through regulating PTEN/PI3K/AKT signalling.
Wang Y, He G, Wang F, Zhang C, Ge Z, Zheng X, Deng H, Yuan C, Zhou B, Tao X, Zhang J, Tang K
Journal of cellular and molecular medicine 2019 Nov;23(11):7535-7544
Journal of cellular and molecular medicine 2019 Nov;23(11):7535-7544
miR-183-5p acts as a potential prognostic biomarker in gastric cancer and regulates cell functions by modulating EEF2.
Li W, Cui X, Qi A, Yan L, Wang T, Li B
Pathology, research and practice 2019 Nov;215(11):152636
Pathology, research and practice 2019 Nov;215(11):152636
Spinosin and 6'''‑Feruloylspinosin protect the heart against acute myocardial ischemia and reperfusion in rats.
Gu M, He P, Lyu C, Liu X, Xu Y, Cheng S, Gu Y, Jia Y
Molecular medicine reports 2019 Nov;20(5):4253-4261
Molecular medicine reports 2019 Nov;20(5):4253-4261
Mechanism of glycyrrhizin on ferroptosis during acute liver failure by inhibiting oxidative stress.
Wang Y, Chen Q, Shi C, Jiao F, Gong Z
Molecular medicine reports 2019 Nov;20(5):4081-4090
Molecular medicine reports 2019 Nov;20(5):4081-4090
Involvement of CaMKII in regulating the release of diplotene-arrested mouse oocytes by pAkt1 (Ser473).
Liu L, Li H, Labbe B, Wang Y, Mao S, Cao Y, Zhao M, Liu S, Yu H, Deng X
Cell cycle (Georgetown, Tex.) 2019 Nov;18(21):2986-2997
Cell cycle (Georgetown, Tex.) 2019 Nov;18(21):2986-2997
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Módis K, Ramanujam VS, Govar AA, Lopez E, Anderson KE, Wang R, Szabo C
Biochemical pharmacology 2019 Nov;169:113604
Biochemical pharmacology 2019 Nov;169:113604
Reprogramming the unfolded protein response for replication by porcine reproductive and respiratory syndrome virus.
Gao P, Chai Y, Song J, Liu T, Chen P, Zhou L, Ge X, Guo X, Han J, Yang H
PLoS pathogens 2019 Nov;15(11):e1008169
PLoS pathogens 2019 Nov;15(11):e1008169
EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production.
Luo Z, Su R, Wang W, Liang Y, Zeng X, Shereen MA, Bashir N, Zhang Q, Zhao L, Wu K, Liu Y, Wu J
PLoS pathogens 2019 Nov;15(11):e1008142
PLoS pathogens 2019 Nov;15(11):e1008142
New FH peptide-modified ultrasonic nanobubbles for delivery of doxorubicin to cancer-associated fibroblasts.
Guo L, Shi D, Meng D, Shang M, Sun X, Zhou X, Liu X, Zhao Y, Li J
Nanomedicine (London, England) 2019 Nov;14(22):2957-2971
Nanomedicine (London, England) 2019 Nov;14(22):2957-2971
Geraniol targets K(V)1.3 ion channel and exhibits anti-inflammatory activity in vitro and in vivo.
Ye CJ, Li SA, Zhang Y, Lee WH
Fitoterapia 2019 Nov;139:104394
Fitoterapia 2019 Nov;139:104394
Citric acid modification of a polymer exhibits antioxidant and anti-inflammatory properties in stem cells and tissues.
Wu X, Dai H, Xu C, Liu L, Li S
Journal of biomedical materials research. Part A 2019 Nov;107(11):2414-2424
Journal of biomedical materials research. Part A 2019 Nov;107(11):2414-2424
Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model.
Song X, Lin NH, Wang YL, Chen B, Wang HX, Hu K
Asian journal of andrology 2019 Nov-Dec;21(6):605-611
Asian journal of andrology 2019 Nov-Dec;21(6):605-611
IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP.
Roy A, Ghosh A, Kumar B, Chandran B
eLife 2019 Nov 4;8
eLife 2019 Nov 4;8
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Hussain Mangi M, Yao J, Dong H, Yang L, Zhou X
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
Comprehensive Identification of PTI Suppressors in Type III Effector Repertoire Reveals that Ralstonia solanacearum Activates Jasmonate Signaling at Two Different Steps.
Nakano M, Mukaihara T
International journal of molecular sciences 2019 Nov 28;20(23)
International journal of molecular sciences 2019 Nov 28;20(23)
CD90 serves as differential modulator of subcutaneous and visceral adipose-derived stem cells by regulating AKT activation that influences adipose tissue and metabolic homeostasis.
Pan Z, Zhou Z, Zhang H, Zhao H, Song P, Wang D, Yin J, Zhao W, Xie Z, Wang F, Li Y, Guo C, Zhu F, Zhang L, Wang Q
Stem cell research & therapy 2019 Nov 28;10(1):355
Stem cell research & therapy 2019 Nov 28;10(1):355
Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies.
Xu M, Yang Q, Xu L, Rao Z, Cao D, Gao M, Liu S
Particle and fibre toxicology 2019 Nov 27;16(1):46
Particle and fibre toxicology 2019 Nov 27;16(1):46
Enhanced Hsa-miR-181d/p-STAT3 and Hsa-miR-181d/p-STAT5A Ratios Mediate the Anticancer Effect of Garcinol in STAT3/5A-Addicted Glioblastoma.
Liu HW, Lee PM, Bamodu OA, Su YK, Fong IH, Yeh CT, Chien MH, Kan IH, Lin CM
Cancers 2019 Nov 27;11(12)
Cancers 2019 Nov 27;11(12)
Protrudin modulates seizure activity through GABA(A) receptor regulation.
Lu X, Yang Y, Zhou R, Li Y, Yang Y, Wang X
Cell death & disease 2019 Nov 27;10(12):897
Cell death & disease 2019 Nov 27;10(12):897
In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species.
Kiechle M, von Einem B, Höfs L, Voehringer P, Grozdanov V, Markx D, Parlato R, Wiesner D, Mayer B, Sakk O, Baumann B, Lukassen S, Liss B, Ekici AB, Ludolph AC, Walther P, Ferger B, McLean PJ, Falkenburger BH, Weishaupt JH, Danzer KM
Cell reports 2019 Nov 26;29(9):2862-2874.e9
Cell reports 2019 Nov 26;29(9):2862-2874.e9
Reshaping Prostate Tumor Microenvironment To Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem.
Lang J, Zhao X, Qi Y, Zhang Y, Han X, Ding Y, Guan J, Ji T, Zhao Y, Nie G
ACS nano 2019 Nov 26;13(11):12357-12371
ACS nano 2019 Nov 26;13(11):12357-12371
Pterostilbene Attenuates Experimental Atherosclerosis through Restoring Catalase-Mediated Redox Balance in Vascular Smooth Muscle Cells.
Wang W, Wang YR, Chen J, Chen YJ, Wang ZX, Geng M, Xu DC, Wang ZY, Li JH, Xu ZD, Pan LL, Sun J
Journal of agricultural and food chemistry 2019 Nov 20;67(46):12752-12760
Journal of agricultural and food chemistry 2019 Nov 20;67(46):12752-12760
ER-mediated anti-tumor effects of shikonin on breast cancer.
Yang Y, Gao W, Tao S, Wang Y, Niu J, Zhao P, Rao C, Yang L
European journal of pharmacology 2019 Nov 15;863:172667
European journal of pharmacology 2019 Nov 15;863:172667
The Molecular Mechanism of Sirt1 Signaling Pathway in Brain Injury of Newborn Rats Exposed to Hyperoxia.
Kang L, Dong W, Ruan Y, Zhang R, Wang X
Biological & pharmaceutical bulletin 2019 Nov 1;42(11):1854-1860
Biological & pharmaceutical bulletin 2019 Nov 1;42(11):1854-1860
Protective effect of peptide DR8 on bleomycin-induced pulmonary fibrosis by regulating the TGF-β/MAPK signaling pathway and oxidative stress.
Wang D, Yan Z, Bu L, An C, Deng B, Zhang J, Rao J, Cheng L, Zhang J, Zhang B, Xie J
Toxicology and applied pharmacology 2019 Nov 1;382:114703
Toxicology and applied pharmacology 2019 Nov 1;382:114703
Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1.
Wang S, Ai H, Liu L, Zhang X, Gao F, Zheng L, Yi J, Sun L, Yu C, Zhao H, Li Y
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E911-E924
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E911-E924
Microglial LOX-1/MAPKs/NF-κB positive loop promotes the vicious cycle of neuroinflammation and neural injury.
Ge X, Zhang DM, Li MM, Zhang Y, Zhu XY, Zhou Y, Peng X, Shen AG
International immunopharmacology 2019 May;70:187-200
International immunopharmacology 2019 May;70:187-200
Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
Wang HF, Wang SS, Zheng M, Dai LL, Wang K, Gao XL, Cao MX, Yu XH, Pang X, Zhang M, Wu JB, Wu JS, Yang X, Tang YJ, Chen Y, Tang YL, Liang XH
Cell proliferation 2019 May;52(3):e12600
Cell proliferation 2019 May;52(3):e12600
Inhibition of microRNA-34a Suppresses Epileptiform Discharges Through Regulating Notch Signaling and Apoptosis in Cultured Hippocampal Neurons.
Wang J, Zheng Y, Cheng X, Xu F, Zhang P, Zhou X, Zhao H
Neurochemical research 2019 May;44(5):1252-1261
Neurochemical research 2019 May;44(5):1252-1261
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Cui Y, Wang Y, Liu G
International journal of molecular medicine 2019 May;43(5):2015-2023
International journal of molecular medicine 2019 May;43(5):2015-2023
Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1.
Das S, Nair RS, Mishra R, Sondarva G, Viswakarma N, Abdelkarim H, Gaponenko V, Rana B, Rana A
Oncogene 2019 May;38(19):3569-3584
Oncogene 2019 May;38(19):3569-3584
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients.
Zhou Q, Xie F, Zhou B, Wang J, Wu B, Li L, Kang Y, Dai R, Jiang Y
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2019 May;30(5):1089-1098
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2019 May;30(5):1089-1098
Effects of miRNA-342-3p in modulating Hedgehog signaling pathway of human umbilical cord mesenchymal stem cells by down-regulating Sufu.
Qing Y, Huang M, Cao Y, Du T, Song K
Oral diseases 2019 May;25(4):1147-1157
Oral diseases 2019 May;25(4):1147-1157
Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.
Li Y, Zheng Q, Sun D, Cui X, Chen S, Bulbul A, Liu S, Yan Q
Journal of cellular physiology 2019 May;234(5):7435-7447
Journal of cellular physiology 2019 May;234(5):7435-7447
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
Fang C, He W, Xu T, Dai J, Xu L, Sun F
Journal of cellular physiology 2019 May;234(5):6254-6262
Journal of cellular physiology 2019 May;234(5):6254-6262
MARCH1 encourages tumour progression of hepatocellular carcinoma via regulation of PI3K-AKT-β-catenin pathways.
Xie L, Dai H, Li M, Yang W, Yu G, Wang X, Wang P, Liu W, Hu X, Zhao M
Journal of cellular and molecular medicine 2019 May;23(5):3386-3401
Journal of cellular and molecular medicine 2019 May;23(5):3386-3401
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
Zhang XJ, Tan H, Shi ZF, Li N, Jia Y, Hao Z
Molecular medicine reports 2019 May;19(5):4109-4118
Molecular medicine reports 2019 May;19(5):4109-4118
RANBP9 suppresses tumor proliferation in colorectal cancer.
Qin C, Zhang Q, Wu G
Oncology letters 2019 May;17(5):4409-4416
Oncology letters 2019 May;17(5):4409-4416
The transcription factor E4bp4 regulates the expression and activity of Cyp3a11 in mice.
Tong Y, Zeng P, Zhang T, Zhao M, Yu P, Wu B
Biochemical pharmacology 2019 May;163:215-224
Biochemical pharmacology 2019 May;163:215-224
Microglia activation induces oxidative injury and decreases SIRT3 expression in dopaminergic neuronal cells.
Jiang DQ, Ma YJ, Wang Y, Lu HX, Mao SH, Zhao SH
Journal of neural transmission (Vienna, Austria : 1996) 2019 May;126(5):559-568
Journal of neural transmission (Vienna, Austria : 1996) 2019 May;126(5):559-568
Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession.
Liu W, Kuang H, Xia Y, Pope ZC, Wang Z, Tang C, Yin D
Experimental physiology 2019 May;104(5):715-728
Experimental physiology 2019 May;104(5):715-728
Alkaloids from Piper nigrum Synergistically Enhanced the Effect of Paclitaxel against Paclitaxel-Resistant Cervical Cancer Cells through the Downregulation of Mcl-1.
Xie Z, Wei Y, Xu J, Lei J, Yu J
Journal of agricultural and food chemistry 2019 May 8;67(18):5159-5168
Journal of agricultural and food chemistry 2019 May 8;67(18):5159-5168
DUXAP10 inhibition attenuates the proliferation and metastasis of hepatocellular carcinoma cells by regulation of the Wnt/β-catenin and PI3K/Akt signaling pathways.
Han K, Li C, Zhang X, Shang L
Bioscience reports 2019 May 31;39(5)
Bioscience reports 2019 May 31;39(5)
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Dong H, Hussain Mangi M, Ni J, Yang L, Zhou X
Cells 2019 May 26;8(5)
Cells 2019 May 26;8(5)
miR-27b-3p/MARCH7 regulates invasion and metastasis of endometrial cancer cells through Snail-mediated pathway.
Liu L, Hu J, Yu T, You S, Zhang Y, Hu L
Acta biochimica et biophysica Sinica 2019 May 23;51(5):492-500
Acta biochimica et biophysica Sinica 2019 May 23;51(5):492-500
TFAP2B overexpression contributes to tumor growth and progression of thyroid cancer through the COX-2 signaling pathway.
Fu X, Zhang H, Chen Z, Yang Z, Shi D, Liu T, Chen W, Yao F, Su X, Deng W, Chen M, Yang A
Cell death & disease 2019 May 21;10(6):397
Cell death & disease 2019 May 21;10(6):397
Long non-coding RNA PVT1 promotes autophagy as ceRNA to target ATG3 by sponging microRNA-365 in hepatocellular carcinoma.
Yang L, Peng X, Jin H, Liu J
Gene 2019 May 20;697:94-102
Gene 2019 May 20;697:94-102
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P
Gene 2019 May 20;697:11-18
Gene 2019 May 20;697:11-18
Downregulation of TSPAN13 by miR-369-3p inhibits cell proliferation in papillary thyroid cancer (PTC).
Li P, Dong M, Wang Z
Bosnian journal of basic medical sciences 2019 May 20;19(2):146-154
Bosnian journal of basic medical sciences 2019 May 20;19(2):146-154
MiR-320a induces diabetic nephropathy via inhibiting MafB.
He M, Wang J, Yin Z, Zhao Y, Hou H, Fan J, Li H, Wen Z, Tang J, Wang Y, Wang DW, Chen C
Aging 2019 May 17;11(10):3055-3079
Aging 2019 May 17;11(10):3055-3079
Using Caffeine and Free Amino Acids To Enhance the Transepithelial Transport of Catechins in Caco-2 Cells.
Wang Y, Zuo Y, Deng S, Zhu F, Liu Q, Wang R, Li T, Cai H, Wan X, Xie Z, Xie Z, Li D
Journal of agricultural and food chemistry 2019 May 15;67(19):5477-5485
Journal of agricultural and food chemistry 2019 May 15;67(19):5477-5485
Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.
Zhu K, Sun J, Kang Z, Zou Z, Wu X, Wang Y, Wu G, Harris RA, Wang J
Brain research 2019 May 1;1710:33-42
Brain research 2019 May 1;1710:33-42
Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.
Zhang Y, Chen Y, Zheng J, Wang J, Duan S, Zhang W, Yan X, Zhu X
Journal of molecular cell biology 2019 May 1;11(5):383-394
Journal of molecular cell biology 2019 May 1;11(5):383-394
ALK5 signaling pathway mediates neurogenesis and functional recovery after cerebral ischemia/reperfusion in rats via Gadd45b.
Zhang K, Zhang Q, Deng J, Li J, Li J, Wen L, Ma J, Li C
Cell death & disease 2019 May 1;10(5):360
Cell death & disease 2019 May 1;10(5):360
Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.
Yang Y, Cui H, Wang X
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):400-408
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):400-408
Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats.
Wu Y, Yue Y, Fu S, Li Y, Wu D, Lv J, Yang D
The Journal of pharmacy and pharmacology 2019 Mar;71(3):400-407
The Journal of pharmacy and pharmacology 2019 Mar;71(3):400-407
Downregulation of Calbindin 1 by miR-454-3p Suppresses Cell Proliferation in Nonsmall Cell Lung Cancer In Vitro.
Jin C, Lin T, Shan L
Cancer biotherapy & radiopharmaceuticals 2019 Mar;34(2):119-127
Cancer biotherapy & radiopharmaceuticals 2019 Mar;34(2):119-127
Identification of novel PROM1 mutations responsible for autosomal recessive maculopathy with rod-cone dystrophy.
Liang J, She X, Chen J, Zhai Y, Liu Y, Zheng K, Gong Y, Zhu H, Luo X, Sun X
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2019 Mar;257(3):619-628
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2019 Mar;257(3):619-628
Inhibition of miR-214-5p attenuates inflammatory chemotaxis and nerve regeneration obstruction after spinal cord injury in rats.
Wang P, Li ZW, Zhu Z, Zhang ZY, Liu J
European review for medical and pharmacological sciences 2019 Mar;23(6):2332-2339
European review for medical and pharmacological sciences 2019 Mar;23(6):2332-2339
Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells.
Wu DD, Liu SY, Gao YR, Lu D, Hong Y, Chen YG, Dong PZ, Wang DY, Li T, Li HM, Ren ZG, Guo JC, He F, Ren XQ, Sun SY, Duan SF, Ji XY
Journal of cellular and molecular medicine 2019 Mar;23(3):1698-1713
Journal of cellular and molecular medicine 2019 Mar;23(3):1698-1713
Mechanical cues modulate cellular uptake of nanoparticles in cancer via clathrin-mediated and caveolae-mediated endocytosis pathways.
Wei X, Wei R, Jiang G, Jia Y, Lou H, Yang Z, Luo D, Huang Q, Xu S, Yang X, Zhou Y, Li X, Ji T, Hu J, Xi L, Ma D, Ye F, Gao Q
Nanomedicine (London, England) 2019 Mar;14(5):613-626
Nanomedicine (London, England) 2019 Mar;14(5):613-626
The effect of early growth response 1 on levels of Amyloid-β 40 peptide in U87MG cells.
Zhao X, Wang X, Su G, Sun Q, Fu J, Zhang H, Teng J
Journal of cellular biochemistry 2019 Mar;120(3):3514-3519
Journal of cellular biochemistry 2019 Mar;120(3):3514-3519
Slc6a13 deficiency promotes Th17 responses during intestinal bacterial infection.
Ren W, Liao Y, Ding X, Jiang Y, Yan J, Xia Y, Tan B, Lin Z, Duan J, Jia X, Yang G, Deng J, Zhu C, Hardwidge PR, Li J, Zhu G, Yin Y
Mucosal immunology 2019 Mar;12(2):531-544
Mucosal immunology 2019 Mar;12(2):531-544
MiR-31-5p acts as a tumor suppressor in renal cell carcinoma by targeting cyclin-dependent kinase 1 (CDK1).
Li Y, Quan J, Chen F, Pan X, Zhuang C, Xiong T, Zhuang C, Li J, Huang X, Ye J, Zhang F, Zhang Z, Gui Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:517-526
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:517-526
TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway.
Bie YN, Gu P, Chen YT, Zhou XX, Tian YG, Yang Q, Li HY, Lin X, Guan YH, Lin TY, Lu X, Shen HF, Fang TX, Liu YM, Xiao D, Gu WW
Journal of translational medicine 2019 Mar 7;17(1):72
Journal of translational medicine 2019 Mar 7;17(1):72
[Tristetraprolin inhibits autophagy in cultured lung cancer cells via the nuclear factor-κB pathway].
Deng X, Luo Q, Dong F, Xu L, Tang X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Mar 30;39(3):313-319
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Mar 30;39(3):313-319
[Citron Rho-interacting serine/threonine kinase knockdown suppresses prostate cancer cell proliferation and metastasis by blocking Hippo-YAP pathway].
Haiping C, Qi X, Dawei L, Qiang W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Mar 30;39(3):257-263
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Mar 30;39(3):257-263
Increased cystatin F levels correlate with decreased cytotoxicity of cytotoxic T cells.
Prunk M, Nanut MP, Sabotic J, Svajger U, Kos J
Radiology and oncology 2019 Mar 3;53(1):57-68
Radiology and oncology 2019 Mar 3;53(1):57-68
COMMD7 Regulates NF-κB Signaling Pathway in Hepatocellular Carcinoma Stem-like Cells.
Zheng L, You N, Huang X, Gu H, Wu K, Mi N, Li J
Molecular therapy oncolytics 2019 Mar 29;12:112-123
Molecular therapy oncolytics 2019 Mar 29;12:112-123
IMB0901 inhibits muscle atrophy induced by cancer cachexia through MSTN signaling pathway.
Liu D, Qiao X, Ge Z, Shang Y, Li Y, Wang W, Chen M, Si S, Chen SZ
Skeletal muscle 2019 Mar 28;9(1):8
Skeletal muscle 2019 Mar 28;9(1):8
Epigenetic Changes at the Birc5 Promoter Induced by YM155 in Synovial Sarcoma.
Mika A, Luelling SE, Pavek A, Nartker C, Heyneman AL, Jones KB, Barrott JJ
Journal of clinical medicine 2019 Mar 24;8(3)
Journal of clinical medicine 2019 Mar 24;8(3)
Antioxidative and Cardioprotective Effects of Schisandra chinensis Bee Pollen Extract on Isoprenaline-Induced Myocardial Infarction in Rats.
Shen Z, Geng Q, Huang H, Yao H, Du T, Chen L, Wu Z, Miao X, Shi P
Molecules (Basel, Switzerland) 2019 Mar 20;24(6)
Molecules (Basel, Switzerland) 2019 Mar 20;24(6)
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
Pettee KM, Becker KN, Alberts AS, Reinard KA, Schroeder JL, Eisenmann KM
Cancers 2019 Mar 20;11(3)
Cancers 2019 Mar 20;11(3)
Tau modulates Schwann cell proliferation, migration and differentiation following peripheral nerve injury.
Yi S, Liu Q, Wang X, Qian T, Wang H, Zha G, Yu J, Wang P, Gu X, Chu D, Li S
Journal of cell science 2019 Mar 18;132(6)
Journal of cell science 2019 Mar 18;132(6)
Role of Paip1 on angiogenesis and invasion in pancreatic cancer.
Guan H, Li N, Wang X, Shan X, Li Z, Lin Z
Experimental cell research 2019 Mar 15;376(2):198-209
Experimental cell research 2019 Mar 15;376(2):198-209
Social context-dependent singing alters molecular markers of dopaminergic and glutamatergic signaling in finch basal ganglia Area X.
So LY, Munger SJ, Miller JE
Behavioural brain research 2019 Mar 15;360:103-112
Behavioural brain research 2019 Mar 15;360:103-112
MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells.
Zhou J, Sun J, Markova DZ, Li S, Kepler CK, Hong J, Huang Y, Chen W, Xu K, Wei F, Ye W
Life sciences 2019 Mar 15;221:274-283
Life sciences 2019 Mar 15;221:274-283
PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma.
Wang DY, Hong Y, Chen YG, Dong PZ, Liu SY, Gao YR, Lu D, Li HM, Li T, Guo JC, He F, Ren XQ, Sun SY, Wu DD, Duan SF, Ji XY
Oncogenesis 2019 Mar 14;8(3):22
Oncogenesis 2019 Mar 14;8(3):22
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
Zhang L, Yang W, Xie H, Wang H, Wang J, Su Q, Li X, Song Y, Wang G, Wang L, Wang Z
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
Mannose receptor C type 2 mediates 1,25(OH)(2)D(3)/vitamin D receptor-regulated collagen metabolism through collagen type 5, alpha 2 chain and matrix metalloproteinase 13 in murine MC3T3-E1 cells.
Dong Y, Yang L, Luo W, Zhu T, Yan W, Kong J, Yuan Z, Zhao Q
Molecular and cellular endocrinology 2019 Mar 1;483:74-86
Molecular and cellular endocrinology 2019 Mar 1;483:74-86
ER stress contributes to high-fat diet-induced decrease of thyroglobulin and hypothyroidism.
Zhang X, Shao S, Zhao L, Yang R, Zhao M, Fang L, Li M, Chen W, Song Y, Xu C, Zhou X, Zhao J, Gao L
American journal of physiology. Endocrinology and metabolism 2019 Mar 1;316(3):E510-E518
American journal of physiology. Endocrinology and metabolism 2019 Mar 1;316(3):E510-E518
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Li YM, Zhang J, Su LJ, Kellum JA, Peng ZY
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis.
Wang D, Zheng J, Liu X, Xue Y, Liu L, Ma J, He Q, Li Z, Cai H, Liu Y
Molecular therapy. Nucleic acids 2019 Mar 1;14:465-482
Molecular therapy. Nucleic acids 2019 Mar 1;14:465-482
Interference of DNAJB6/MRJ Isoform Switch by Morpholino Inhibits Replication of HIV-1 and RSV.
Ko SH, Liau YJ, Chi YH, Lai MJ, Chiang YP, Lu CY, Chang LY, Tarn WY, Huang LM
Molecular therapy. Nucleic acids 2019 Mar 1;14:251-261
Molecular therapy. Nucleic acids 2019 Mar 1;14:251-261
Glucose Is Involved in the Dynamic Regulation of m6A in Patients With Type 2 Diabetes.
Yang Y, Shen F, Huang W, Qin S, Huang JT, Sergi C, Yuan BF, Liu SM
The Journal of clinical endocrinology and metabolism 2019 Mar 1;104(3):665-673
The Journal of clinical endocrinology and metabolism 2019 Mar 1;104(3):665-673
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta EC, Vieira-Vieira CH, Hick T, Wessels HH, Figini D, Moschall R, Medenbach J, Ohler U, Granneman S, Selbach M, Beckmann BM
Nature communications 2019 Mar 1;10(1):990
Nature communications 2019 Mar 1;10(1):990
HEV ORF3 downregulatesCD14 and CD64 to impair macrophages phagocytosis through inhibiting JAK/STAT pathway.
Lei Q, Li L, Huang W, Qin B, Zhang S
Journal of medical virology 2019 Jun;91(6):1112-1119
Journal of medical virology 2019 Jun;91(6):1112-1119
Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.
Jiang X, Gu T, Liu Y, Gao S, Shi E, Zhang G
Therapeutic hypothermia and temperature management 2019 Jun;9(2):118-127
Therapeutic hypothermia and temperature management 2019 Jun;9(2):118-127
Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner.
Yan M, Yu Y, Mao X, Feng J, Wang Y, Chen H, Xie K, Yu Y
International immunopharmacology 2019 Jun;71:61-67
International immunopharmacology 2019 Jun;71:61-67
Hepatic miR-181b-5p Contributes to Glycogen Synthesis Through Targeting EGR1.
Wang S, Liang C, Ai H, Yang M, Yi J, Liu L, Song Z, Bao Y, Li Y, Sun L, Zhao H
Digestive diseases and sciences 2019 Jun;64(6):1548-1559
Digestive diseases and sciences 2019 Jun;64(6):1548-1559
RNase L facilitates the repair of DNA double-strand breaks through the nonhomologous end-joining pathway.
Zhong Y, Pan B, Zhu J, Fu H, Zheng X
FEBS letters 2019 Jun;593(11):1190-1200
FEBS letters 2019 Jun;593(11):1190-1200
The E3 ubiquitin ligase HECW1 targets thyroid transcription factor 1 (TTF1/NKX2.1) for its degradation in the ubiquitin-proteasome system.
Liu J, Dong S, Li L, Wang H, Zhao J, Zhao Y
Cellular signalling 2019 Jun;58:91-98
Cellular signalling 2019 Jun;58:91-98
TGF-β-induced long non-coding RNA MIR155HG promotes the progression and EMT of laryngeal squamous cell carcinoma by regulating the miR-155-5p/SOX10 axis.
Cui W, Meng W, Zhao L, Cao H, Chi W, Wang B
International journal of oncology 2019 Jun;54(6):2005-2018
International journal of oncology 2019 Jun;54(6):2005-2018
Immunoglobulin‑like transcript 4 and human leukocyte antigen‑G interaction promotes the progression of human colorectal cancer.
Cai Z, Wang L, Han Y, Gao W, Wei X, Gong R, Zhu M, Sun Y, Yu S
International journal of oncology 2019 Jun;54(6):1943-1954
International journal of oncology 2019 Jun;54(6):1943-1954
Dynamic bioenergetic alterations in colorectal adenomatous polyps and adenocarcinomas.
Lin WR, Chiang JM, Lim SN, Su MY, Chen TH, Huang SW, Chen CW, Wu RC, Tsai CL, Lin YH, Alison MR, Hsieh SY, Yu JS, Chiu CT, Yeh CT
EBioMedicine 2019 Jun;44:334-345
EBioMedicine 2019 Jun;44:334-345
Umbilical Cord Blood Mesenchymal Stem Cells Enhance Lipopolysaccharide-Induced IL-10 and IL-37 Production in THP-1 Cells.
Zhou T, Sun Y, Wang Y, Chen X, Zhuo L, Bu L, Xu S, Han J, Li X, Shi J
Inflammation 2019 Jun;42(3):987-993
Inflammation 2019 Jun;42(3):987-993
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, Zhang S, Liu Y, Xiang Y, Liu J, Shi M
Oncogene 2019 Jun;38(23):4637-4654
Oncogene 2019 Jun;38(23):4637-4654
miR-618 Suppresses Metastasis in Gastric Cancer by Downregulating the Expression of TGF-β2.
Shi J, Gong L, Chen L, Luo J, Song G, Xu J, Lv Z, Tao H, Xia Y, Ye Z
Anatomical record (Hoboken, N.J. : 2007) 2019 Jun;302(6):931-940
Anatomical record (Hoboken, N.J. : 2007) 2019 Jun;302(6):931-940
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
Zhou PT, Wang LP, Qu MJ, Shen H, Zheng HR, Deng LD, Ma YY, Wang YY, Wang YT, Tang YH, Tian HL, Zhang ZJ, Yang GY
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, Chen X, Yu X, Sun L, Yu X
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
TSP-1 is downregulated and inversely correlates with miR-449c expression in Cushing's disease.
Ren J, Gu C, Yang Y, Xue J, Sun Y, Jian F, Chen D, Bian L, Sun Q
Journal of cellular and molecular medicine 2019 Jun;23(6):4097-4110
Journal of cellular and molecular medicine 2019 Jun;23(6):4097-4110
C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo.
Choi SY, Lopez-Gonzalez R, Krishnan G, Phillips HL, Li AN, Seeley WW, Yao WD, Almeida S, Gao FB
Nature neuroscience 2019 Jun;22(6):851-862
Nature neuroscience 2019 Jun;22(6):851-862
Trichostatin A‑induced miR‑30a‑5p regulates apoptosis and proliferation of keloid fibroblasts via targeting BCL2.
Jian X, Qu L, Wang Y, Zou Q, Zhao Q, Chen S, Gao X, Chen H, He C
Molecular medicine reports 2019 Jun;19(6):5251-5262
Molecular medicine reports 2019 Jun;19(6):5251-5262
High expression of DLC family proteins predicts better prognosis and inhibits tumor progression in NSCLC.
Sun L, Sun J, Song JD
Molecular medicine reports 2019 Jun;19(6):4881-4889
Molecular medicine reports 2019 Jun;19(6):4881-4889
CRKII overexpression promotes the in vitro proliferation, migration and invasion potential of murine hepatocarcinoma Hca-P cells.
Zhou Z, Sun X, Guo C, Sun MZ, Liu S
Oncology letters 2019 Jun;17(6):5169-5174
Oncology letters 2019 Jun;17(6):5169-5174
Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice.
Deng C, Li J, Li L, Sun F, Xie J
Experimental and therapeutic medicine 2019 Jun;17(6):4517-4521
Experimental and therapeutic medicine 2019 Jun;17(6):4517-4521
MiR-219a-5p enhances cisplatin sensitivity of human non-small cell lung cancer by targeting FGF9.
Rao C, Miao X, Zhao G, Zhang C, Shen H, Dong C, Yang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108662
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108662
Salidroside inhibits migration and invasion of poorly differentiated thyroid cancer cells.
Shang H, Wang S, Yao J, Guo C, Dong J, Liao L
Thoracic cancer 2019 Jun;10(6):1469-1478
Thoracic cancer 2019 Jun;10(6):1469-1478
A Novel lncRNA IHS Promotes Tumor Proliferation and Metastasis in HCC by Regulating the ERK- and AKT/GSK-3β-Signaling Pathways.
Chen Z, Yu W, Zhou Q, Zhang J, Jiang H, Hao D, Wang J, Zhou Z, He C, Xiao Z
Molecular therapy. Nucleic acids 2019 Jun 7;16:707-720
Molecular therapy. Nucleic acids 2019 Jun 7;16:707-720
lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer.
Yu G, Zhou H, Yao W, Meng L, Lang B
Molecular therapy. Nucleic acids 2019 Jun 7;16:257-271
Molecular therapy. Nucleic acids 2019 Jun 7;16:257-271
TLR2 promotes development and progression of human glioma via enhancing autophagy.
Li C, Ma L, Liu Y, Li Z, Wang Q, Chen Z, Geng X, Han X, Sun J, Li Z
Gene 2019 Jun 5;700:52-59
Gene 2019 Jun 5;700:52-59
Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.
Chen H, Liu Y, Jiang CJ, Chen YM, Li H, Liu QA
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 5;25:4176-4185
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 5;25:4176-4185
Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus.
Criado-Marrero M, Gebru NT, Gould LA, Smith TM, Kim S, Blackburn RJ, Dickey CA, Blair LJ
International journal of molecular sciences 2019 Jun 4;20(11)
International journal of molecular sciences 2019 Jun 4;20(11)
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
Zhou J, Zheng J, Zhang Y, Zheng P, Tang T, Luo JK, Cui HJ, Song RR, Wang Y
ACS omega 2019 Jun 30;4(6):10185-10191
ACS omega 2019 Jun 30;4(6):10185-10191
Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis.
Ran L, Wang X, Mi A, Liu Y, Wu J, Wang H, Guo M, Sun J, Liu B, Li Y, Wang D, Jiang R, Wang N, Gao W, Zeng L, Huang L, Chen X, LeRoith D, Liang B, Li X, Wu Y
iScience 2019 Jun 28;16:106-121
iScience 2019 Jun 28;16:106-121
KLF7 promotes polyamine biosynthesis and glioma development through transcriptionally activating ASL.
Guan F, Kang Z, Zhang JT, Xue NN, Yin H, Wang L, Mao BB, Peng WC, Zhang BL, Liang X, Hu ZQ
Biochemical and biophysical research communications 2019 Jun 18;514(1):51-57
Biochemical and biophysical research communications 2019 Jun 18;514(1):51-57
Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma.
Zhang C, Huang H, Zhang J, Wu Q, Chen X, Huang T, Li W, Liu Y, Zhang J
Cell death & disease 2019 Jun 17;10(7):477
Cell death & disease 2019 Jun 17;10(7):477
Formiminotransferase Cyclodeaminase Suppresses Hepatocellular Carcinoma by Modulating Cell Apoptosis, DNA Damage, and Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Pathway.
Chen J, Chen Z, Huang Z, Yu H, Li Y, Huang W
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 16;25:4474-4484
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 16;25:4474-4484
Effect of CAPE-pNO(2) against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
Li S, Huang Q, Zhang L, Qiao X, Zhang Y, Tang F, Li Z
European journal of pharmacology 2019 Jun 15;853:1-10
European journal of pharmacology 2019 Jun 15;853:1-10
Synergistic effects of 7-O-geranylquercetin and siRNAs on the treatment of human breast cancer.
Zuo J, Jiang Y, Zhang E, Chen Y, Liang Z, Zhu J, Zhao Y, Xu H, Liu G, Liu J, Wang W, Zhang S, Zhen Y
Life sciences 2019 Jun 15;227:145-152
Life sciences 2019 Jun 15;227:145-152
Long noncoding RNA HOXA11-AS promotes gastric cancer cell proliferation and invasion via SRSF1 and functions as a biomarker in gastric cancer.
Liu Y, Zhang YM, Ma FB, Pan SR, Liu BZ
World journal of gastroenterology 2019 Jun 14;25(22):2763-2775
World journal of gastroenterology 2019 Jun 14;25(22):2763-2775
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling.
Zhao Y, Xiang R, Peng X, Dong Q, Li D, Yu G, Xiao L, Qin S, Huang W
Respiratory research 2019 Jun 14;20(1):121
Respiratory research 2019 Jun 14;20(1):121
miR-21 promotes NLRP3 inflammasome activation to mediate pyroptosis and endotoxic shock.
Xue Z, Xi Q, Liu H, Guo X, Zhang J, Zhang Z, Li Y, Yang G, Zhou D, Yang H, Zhang L, Zhang Q, Gu C, Yang J, Da Y, Yao Z, Duo S, Zhang R
Cell death & disease 2019 Jun 12;10(6):461
Cell death & disease 2019 Jun 12;10(6):461
Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells.
Song Y, Shao L, Xue Y, Ruan X, Liu X, Yang C, Zheng J, Shen S, Chen J, Li Z, Liu Y
Journal of experimental & clinical cancer research : CR 2019 Jun 11;38(1):248
Journal of experimental & clinical cancer research : CR 2019 Jun 11;38(1):248
CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4(+) T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4(+) T cell enrichment in humanized mice.
Xiao Q, Chen S, Wang Q, Liu Z, Liu S, Deng H, Hou W, Wu D, Xiong Y, Li J, Guo D
Retrovirology 2019 Jun 11;16(1):15
Retrovirology 2019 Jun 11;16(1):15
MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling.
Yuan J, Tan L, Yin Z, Zhu W, Tao K, Wang G, Shi W, Gao J
Cell death & disease 2019 Jun 11;10(6):454
Cell death & disease 2019 Jun 11;10(6):454
Blocking autophagy flux promotes interferon-alpha-mediated apoptosis in head and neck squamous cell carcinoma.
Yang W, Jiang C, Xia W, Ju H, Jin S, Liu S, Zhang L, Ren G, Ma H, Ruan M, Hu J
Cancer letters 2019 Jun 1;451:34-47
Cancer letters 2019 Jun 1;451:34-47
C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes.
Guo Q, Hu H, Liu X, Yang D, Yin Y, Zhang B, He H, Oh Y, Wu Q, Liu C, Gu N
American journal of physiology. Endocrinology and metabolism 2019 Jun 1;316(6):E1081-E1092
American journal of physiology. Endocrinology and metabolism 2019 Jun 1;316(6):E1081-E1092
Oxidative stress: One potential factor for arsenite-induced increase of N(6)-methyladenosine in human keratinocytes.
Zhao T, Li X, Sun D, Zhang Z
Environmental toxicology and pharmacology 2019 Jul;69:95-103
Environmental toxicology and pharmacology 2019 Jul;69:95-103
Panobinostat (LBH589) inhibits Wnt/β-catenin signaling pathway via upregulating APCL expression in breast cancer.
Qin G, Li Y, Xu X, Wang X, Zhang K, Tang Y, Qiu H, Shi D, Zhang C, Long Q, Lee K, Zhai Q, Wang S, Chen M, Deng W
Cellular signalling 2019 Jul;59:62-75
Cellular signalling 2019 Jul;59:62-75
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
Mesenchymal stem cell-secreted factors delayed spermatogenesis injuries induced by busulfan involving intercellular adhesion molecule regulation.
Cai YT, Xiong CL, Shen SL, Rao JP, Liu TS, Qiu F
Andrologia 2019 Jul;51(6):e13285
Andrologia 2019 Jul;51(6):e13285
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Wu D, Zhong P, Wang J, Wang H
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Treatment with a brain-selective prodrug of 17β-estradiol improves cognitive function in Alzheimer's disease mice by regulating klf5-NF-κB pathway.
Yan W, Wu J, Song B, Luo Q, Xu Y
Naunyn-Schmiedeberg's archives of pharmacology 2019 Jul;392(7):879-886
Naunyn-Schmiedeberg's archives of pharmacology 2019 Jul;392(7):879-886
Losartan protects against myocardial ischemia and reperfusion injury via vascular integrity preservation.
Li Y, Yao Y, Li J, Chen Q, Zhang L, Wang QK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8555-8564
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8555-8564
NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway.
Hu W, Li X, Cheng R, Ke J, Liu Y, Ma M, Cao Y, Liu D
Archives of dermatological research 2019 Jul;311(5):399-410
Archives of dermatological research 2019 Jul;311(5):399-410
eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop.
Smirnova VV, Shestakova ED, Bikmetov DV, Chugunova AA, Osterman IA, Serebryakova MV, Sergeeva OV, Zatsepin TS, Shatsky IN, Terenin IM
RNA (New York, N.Y.) 2019 Jul;25(7):757-767
RNA (New York, N.Y.) 2019 Jul;25(7):757-767
The long noncoding RNA NORAD enhances the TGF-β pathway to promote hepatocellular carcinoma progression by targeting miR-202-5p.
Yang X, Cai JB, Peng R, Wei CY, Lu JC, Gao C, Shen ZZ, Zhang PF, Huang XY, Ke AW, Shi GM, Fan J
Journal of cellular physiology 2019 Jul;234(7):12051-12060
Journal of cellular physiology 2019 Jul;234(7):12051-12060
Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3.
Ahmmed B, Kampo S, Khan M, Faqeer A, Kumar SP, Yulin L, Liu JW, Yan Q
Journal of cellular physiology 2019 Jul;234(7):10680-10697
Journal of cellular physiology 2019 Jul;234(7):10680-10697
MiR-511-5p functions as a tumor suppressor and a predictive of prognosis in colorectal cancer by directly targeting GPR116.
Wang C, Fan HQ, Zhang YW
European review for medical and pharmacological sciences 2019 Jul;23(14):6119-6130
European review for medical and pharmacological sciences 2019 Jul;23(14):6119-6130
Fr‑HMGB1 and ds‑HMGB1 activate the kynurenine pathway via different mechanisms in association with depressive‑like behavior.
Wang B, Lian YJ, Su WJ, Liu LL, Li JM, Jiang CL, Wang YX
Molecular medicine reports 2019 Jul;20(1):359-367
Molecular medicine reports 2019 Jul;20(1):359-367
MicroRNA-124 regulates TRAF6 expression and functions as an independent prognostic factor in colorectal cancer.
Wei C, Lei L, Hui H, Tao Z
Oncology letters 2019 Jul;18(1):856-863
Oncology letters 2019 Jul;18(1):856-863
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, Chen A, Chen S, Wu F, Hu Q, Zhou S
Oncology letters 2019 Jul;18(1):609-616
Oncology letters 2019 Jul;18(1):609-616
Knockdown of endothelin receptor B inhibits the progression of triple-negative breast cancer.
Gu X, Han S, Cui M, Xue J, Ai L, Sun L, Zhu X, Wang Y, Liu C
Annals of the New York Academy of Sciences 2019 Jul;1448(1):5-18
Annals of the New York Academy of Sciences 2019 Jul;1448(1):5-18
PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-β1-induced EMT.
Ma R, Liu Q, Zheng S, Liu T, Tan D, Lu X
Journal of cellular biochemistry 2019 Jul;120(7):11539-11550
Journal of cellular biochemistry 2019 Jul;120(7):11539-11550
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
Chang Z, Zhang P, Zhang M, Jun F, Hu Z, Yang J, Wu Y, Zhou R
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Zhang W, Lu Y, Li X, Zhang J, Lin W, Zhang W, Zheng L, Li X
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
TRIM28 protects CARM1 from proteasome-mediated degradation to prevent colorectal cancer metastasis.
Cui J, Hu J, Ye Z, Fan Y, Li Y, Wang G, Wang L, Wang Z
Science bulletin 2019 Jul 30;64(14):986-997
Science bulletin 2019 Jul 30;64(14):986-997
Inhibition of DHCR24 increases the cisplatin-induced damage to cochlear hair cells in vitro.
Tian KY, Chang HM, Wang J, Qi MH, Wang WL, Qiu Y, Liang K, Chen FQ, Zha DJ, Qiu JH
Neuroscience letters 2019 Jul 27;706:99-104
Neuroscience letters 2019 Jul 27;706:99-104
Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway.
Wang N, Wang M
BMC anesthesiology 2019 Jul 27;19(1):134
BMC anesthesiology 2019 Jul 27;19(1):134
Small Nucleolar RNA Host Gene 12 (SNHG12) Promotes Proliferation and Invasion of Laryngeal Cancer Cells via Sponging miR-129-5p and Potentiating WW Domain-Containing E3 Ubiquitin Protein Ligase 1 (WWP1) Expression.
Li J, Sun S, Chen W, Yuan K
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 26;25:5552-5560
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 26;25:5552-5560
Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients.
Li J, Yang G, Liu S, Wang L, Liang Z, Zhang H
Clinical epigenetics 2019 Jul 23;11(1):107
Clinical epigenetics 2019 Jul 23;11(1):107
Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells.
Zhang Q, Liu RX, Chan KW, Hu J, Zhang J, Wei L, Tan H, Yang X, Liu H
Journal of experimental & clinical cancer research : CR 2019 Jul 19;38(1):320
Journal of experimental & clinical cancer research : CR 2019 Jul 19;38(1):320
Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis.
Yao Y, Chen X, Yang H, Chen W, Qian Y, Yan Z, Liao T, Yao W, Wu W, Yu T, Chen Y, Zhang Y
Journal of experimental & clinical cancer research : CR 2019 Jul 19;38(1):318
Journal of experimental & clinical cancer research : CR 2019 Jul 19;38(1):318
Effect of transcutaneous electrical acupoint stimulation on protecting against radiotherapy- induced ovarian damage in mice.
Tan R, He Y, Zhang S, Pu D, Wu J
Journal of ovarian research 2019 Jul 19;12(1):65
Journal of ovarian research 2019 Jul 19;12(1):65
Sirtuin1 activator SRT2183 suppresses glioma cell growth involving activation of endoplasmic reticulum stress pathway.
Ye T, Wei L, Shi J, Jiang K, Xu H, Hu L, Kong L, Zhang Y, Meng S, Piao H
BMC cancer 2019 Jul 18;19(1):706
BMC cancer 2019 Jul 18;19(1):706
F-box protein FBXO30 mediates retinoic acid receptor γ ubiquitination and regulates BMP signaling in neural tube defects.
Cheng X, Pei P, Yu J, Zhang Q, Li D, Xie X, Wu J, Wang S, Zhang T
Cell death & disease 2019 Jul 18;10(8):551
Cell death & disease 2019 Jul 18;10(8):551
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Zhang M, Zhao J, Deng J, Duan Z, Zhu C, Fan D
Food & function 2019 Jul 17;10(7):4124-4133
Food & function 2019 Jul 17;10(7):4124-4133
Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo.
Sun X, Feng X, Zheng D, Li A, Li C, Li S, Zhao Z
Clinical science (London, England : 1979) 2019 Jul 15;133(13):1523-1536
Clinical science (London, England : 1979) 2019 Jul 15;133(13):1523-1536
Decline of p300 contributes to cell senescence and growth inhibition of hUC-MSCs through p53/p21 signaling pathway.
Li Y, Zhong H, Wu M, Tan B, Zhao L, Yi Q, Xu X, Pan H, Bi Y, Yang K
Biochemical and biophysical research communications 2019 Jul 12;515(1):24-30
Biochemical and biophysical research communications 2019 Jul 12;515(1):24-30
CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.
Luo Y, Liu Y, Wu L, Ma X, Liu Q, Huang F, Zhang X, Zhang Y, Zhang J, Luo H, Yang Y, Lu G, Tang X, Li L, Zeng Y, Pan T, Zhang H
Journal of immunology (Baltimore, Md. : 1950) 2019 Jul 1;203(1):269-281
Journal of immunology (Baltimore, Md. : 1950) 2019 Jul 1;203(1):269-281
Cloning, expression of the truncation of recombinant peroxidase derived from millet bran and its reversal effects on 5-Fu resistance in colorectal cancer.
Zhang X, Shan S, Li H, Shi J, Lu Y, Li Z
International journal of biological macromolecules 2019 Jul 1;132:871-879
International journal of biological macromolecules 2019 Jul 1;132:871-879
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Liu SQ, Xu CY, Wu WH, Fu ZH, He SW, Qin MB, Huang JA
International journal of oncology 2019 Jan;54(1):41-52
International journal of oncology 2019 Jan;54(1):41-52
Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway.
Zhang Q, Tao X, Xia S, Qu J, Song H, Liu J, Li H, Shang D
Oncology reports 2019 Jan;41(1):270-278
Oncology reports 2019 Jan;41(1):270-278
MicroRNA-31-5p enhances the Warburg effect via targeting FIH.
Zhu B, Cao X, Zhang W, Pan G, Yi Q, Zhong W, Yan D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):545-556
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):545-556
MiR-126-3p suppresses the growth, migration and invasion of NSCLC via targeting CCR1.
Liu R, Zhang YS, Zhang S, Cheng ZM, Yu JL, Zhou S, Song J
European review for medical and pharmacological sciences 2019 Jan;23(2):679-689
European review for medical and pharmacological sciences 2019 Jan;23(2):679-689
DLG5 suppresses breast cancer stem cell-like characteristics to restore tamoxifen sensitivity by inhibiting TAZ expression.
Liu J, Li J, Li P, Jiang Y, Chen H, Wang R, Cao F, Liu P
Journal of cellular and molecular medicine 2019 Jan;23(1):512-521
Journal of cellular and molecular medicine 2019 Jan;23(1):512-521
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
Zhao X, Zheng F, Li Y, Hao J, Tang Z, Tian C, Yang Q, Zhu T, Diao C, Zhang C, Chen M, Hu S, Guo P, Zhang L, Liao Y, Yu W, Chen M, Zou L, Guo W, Deng W
Redox biology 2019 Jan;20:427-441
Redox biology 2019 Jan;20:427-441
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Zhang T, Li Q, Wang L, Li G
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
Zheng L, Han X, Hu Y, Zhao X, Yin L, Xu L, Qi Y, Xu Y, Han X, Liu K, Peng J
Pharmacological research 2019 Jan;139:431-439
Pharmacological research 2019 Jan;139:431-439
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J
Free radical biology & medicine 2019 Jan;130:576-591
Free radical biology & medicine 2019 Jan;130:576-591
Estrogen receptor variant ER-α36 promotes tamoxifen agonist activity in glioblastoma cells.
Qu C, Ma J, Zhang Y, Han C, Huang L, Shen L, Li H, Wang X, Liu J, Zou W
Cancer science 2019 Jan;110(1):221-234
Cancer science 2019 Jan;110(1):221-234
mircroRNA-152 prevents the malignant progression of atherosclerosis via down-regulation of KLF5.
Wang W, Zhang Y, Wang L, Li J, Li Y, Yang X, Wu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2409-2414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2409-2414
Exendin-4 promotes actin cytoskeleton rearrangement and protects cells from Nogo-A-Δ20 mediated spreading inhibition and growth cone collapse by down-regulating RhoA expression and activation via the PI3K pathway.
Zhao F, Li J, Wang R, Xu H, Ma K, Kong X, Sun Z, Niu X, Jiang J, Liu B, Li B, Duan F, Chen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:135-143
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:135-143
Tetramethylpyrazine (TMP) ameliorates corneal neovascularization via regulating cell infiltration into cornea after alkali burn.
Wu Y, Xu Z, Yang Y, Qiu J, Yang M, Wu C, Lai Z, Tang M, Ge J, Yu K, Zhuang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1041-1051
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1041-1051
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
Yang DL, Gan ML, Tan Y, Ge GH, Li Q, Jiang YZ, Tang GQ, Li MZ, Wang JY, Li XW, Zhang SH, Zhu L
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
Silencing of Transcription Factor Sp1 Promotes SN1 Transporter Regulation by Ammonia in Mouse Cortical Astrocytes.
Dąbrowska K, Zielińska M
International journal of molecular sciences 2019 Jan 9;20(2)
International journal of molecular sciences 2019 Jan 9;20(2)
Long non-coding RNA Linc00320 inhibits glioma cell proliferation through restraining Wnt/β-catenin signaling.
Tian S, Liu W, Pan Y, Zhan S
Biochemical and biophysical research communications 2019 Jan 8;508(2):458-464
Biochemical and biophysical research communications 2019 Jan 8;508(2):458-464
Role of the P2X7 receptor in inflammation-mediated changes in the osteogenesis of periodontal ligament stem cells.
Xu XY, He XT, Wang J, Li X, Xia Y, Tan YZ, Chen FM
Cell death & disease 2019 Jan 8;10(1):20
Cell death & disease 2019 Jan 8;10(1):20
miR-632 promotes gastric cancer progression by accelerating angiogenesis in a TFF1-dependent manner.
Shi Y, Huang X, Chen G, Wang Y, Liu Y, Xu W, Tang S, Guleng B, Liu J, Ren J
BMC cancer 2019 Jan 7;19(1):14
BMC cancer 2019 Jan 7;19(1):14
Microvesicles from human adipose stem cells promote wound healing by optimizing cellular functions via AKT and ERK signaling pathways.
Ren S, Chen J, Duscher D, Liu Y, Guo G, Kang Y, Xiong H, Zhan P, Wang Y, Wang C, Machens HG, Chen Z
Stem cell research & therapy 2019 Jan 31;10(1):47
Stem cell research & therapy 2019 Jan 31;10(1):47
Aberrant methylation and downregulation of ZNF667-AS1 and ZNF667 promote the malignant progression of laryngeal squamous cell carcinoma.
Meng W, Cui W, Zhao L, Chi W, Cao H, Wang B
Journal of biomedical science 2019 Jan 26;26(1):13
Journal of biomedical science 2019 Jan 26;26(1):13
PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε.
Wu F, Niu Z, Zhou B, Li P, Qian F
Viruses 2019 Jan 24;11(2)
Viruses 2019 Jan 24;11(2)
Circular RNA circMTO1 suppresses bladder cancer metastasis by sponging miR-221 and inhibiting epithelial-to-mesenchymal transition.
Li Y, Wan B, Liu L, Zhou L, Zeng Q
Biochemical and biophysical research communications 2019 Jan 22;508(4):991-996
Biochemical and biophysical research communications 2019 Jan 22;508(4):991-996
Long noncoding FOXD2-AS1 is activated by CREB1 and promotes cell proliferation and metastasis in glioma by sponging miR-185 through targeting AKT1.
Dong H, Cao W, Xue J
Biochemical and biophysical research communications 2019 Jan 22;508(4):1074-1081
Biochemical and biophysical research communications 2019 Jan 22;508(4):1074-1081
Secalonic Acid-F, a Novel Mycotoxin, Represses the Progression of Hepatocellular Carcinoma via MARCH1 Regulation of the PI3K/AKT/β-catenin Signaling Pathway.
Xie L, Li M, Liu D, Wang X, Wang P, Dai H, Yang W, Liu W, Hu X, Zhao M
Molecules (Basel, Switzerland) 2019 Jan 22;24(3)
Molecules (Basel, Switzerland) 2019 Jan 22;24(3)
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Shi H, Wang XL, Quan HF, Yan L, Pei XY, Wang R, Peng XD
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway.
Zhang X, Yin Y, Yue L, Gong L
Investigative ophthalmology & visual science 2019 Jan 2;60(1):407-419
Investigative ophthalmology & visual science 2019 Jan 2;60(1):407-419
Retinal Neuron Is More Sensitive to Blue Light-Induced Damage than Glia Cell Due to DNA Double-Strand Breaks.
Chen P, Lai Z, Wu Y, Xu L, Cai X, Qiu J, Yang P, Yang M, Zhou P, Zhuang J, Ge J, Yu K, Zhuang J
Cells 2019 Jan 18;8(1)
Cells 2019 Jan 18;8(1)
Engineering a conserved RNA regulatory protein repurposes its biological function in vivo.
Bhat VD, McCann KL, Wang Y, Fonseca DR, Shukla T, Alexander JC, Qiu C, Wickens M, Lo TW, Tanaka Hall TM, Campbell ZT
eLife 2019 Jan 17;8
eLife 2019 Jan 17;8
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb.
Ma X, Yang T, Luo Y, Wu L, Jiang Y, Song Z, Pan T, Liu B, Liu G, Liu J, Yu F, He Z, Zhang W, Yang J, Liang L, Guan Y, Zhang X, Li L, Cai W, Tang X, Gao S, Deng K, Zhang H
eLife 2019 Jan 17;8
eLife 2019 Jan 17;8
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, Wang H, Zhang B, Qiu J, Deng F, Guan W
Nucleic acids research 2019 Jan 10;47(1):362-374
Nucleic acids research 2019 Jan 10;47(1):362-374
ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition.
Tang J, Liu C, Xu B, Wang D, Ma Z, Chang X
Experimental cell research 2019 Jan 1;374(1):46-68
Experimental cell research 2019 Jan 1;374(1):46-68
miR-429 and miR-424-5p inhibit cell proliferation and Ca(2+) influx by downregulating CaSR in pulmonary artery smooth muscle cells.
Li C, Qin F, Xue M, Lei Y, Hu F, Xu H, Sun G, Wang T, Guo M
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C111-C120
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C111-C120
Epigenetic changes in preterm birth placenta suggest a role for ADAMTS genes in spontaneous preterm birth.
Mani S, Ghosh J, Lan Y, Senapati S, Ord T, Sapienza C, Coutifaris C, Mainigi M
Human molecular genetics 2019 Jan 1;28(1):84-95
Human molecular genetics 2019 Jan 1;28(1):84-95
Distribution patterns of the zebrafish neuronal intermediate filaments inaa and inab.
Liao ML, Peng WH, Kan D, Chien CL
Journal of neuroscience research 2019 Feb;97(2):202-214
Journal of neuroscience research 2019 Feb;97(2):202-214
Effects of Platycodin D on S100A8/A9-induced inflammatory response in murine mammary carcinoma 4T1 cells.
Ye Y, Pei L, Ding J, Wu C, Sun C, Liu S
International immunopharmacology 2019 Feb;67:239-247
International immunopharmacology 2019 Feb;67:239-247
Semaphoring 4D is required for the induction of antioxidant stress and anti-inflammatory effects of dihydromyricetin in colon cancer.
Liang J, Wu J, Wang F, Zhang P, Zhang X
International immunopharmacology 2019 Feb;67:220-230
International immunopharmacology 2019 Feb;67:220-230
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, Zhang Y, Li B, Shan Y
Molecular nutrition & food research 2019 Feb;63(4):e1800795
Molecular nutrition & food research 2019 Feb;63(4):e1800795
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
Ullah O, Li Z, Ali I, Xu L, Liu H, Jin HZ, Fang YY, Jin QG, Fang N
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
Ahmmed B, Khan MN, Nisar MA, Kampo S, Zheng Q, Li Y, Yan Q
International journal of oncology 2019 Feb;54(2):431-442
International journal of oncology 2019 Feb;54(2):431-442
Establishment and evaluation of a novel mouse model of peri/postmenopausal depression.
Zhang L, Cao LL, Yang DD, Ding JH, Guo XD, Xue TF, Zhao XJ, Sun XL
Heliyon 2019 Feb;5(2):e01195
Heliyon 2019 Feb;5(2):e01195
Ginsenoside-Rb3 inhibits endothelial-mesenchymal transition of cardiac microvascular endothelial cells.
Yang L, Liu Q, Yu Y, Xu H, Chen S, Shi S
Herz 2019 Feb;44(1):60-68
Herz 2019 Feb;44(1):60-68
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
Li W, Wang D, Sun X, Zhang Y, Wang L, Suo J
International journal of molecular medicine 2019 Feb;43(2):914-926
International journal of molecular medicine 2019 Feb;43(2):914-926
MicroRNA-155 Suppresses Mesangial Cell Proliferation and TGF-β1 Production via Inhibiting CXCR5-ERK Signaling Pathway in Lupus Nephritis.
Kong J, Li L, Lu Z, Song J, Yan J, Yang J, Gu Z, Da Z
Inflammation 2019 Feb;42(1):255-263
Inflammation 2019 Feb;42(1):255-263
TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways.
Ye J, Chu C, Chen M, Shi Z, Gan S, Qu F, Pan X, Yang Q, Tian Y, Wang L, Yang W, Cui X
Oncology reports 2019 Feb;41(2):1169-1179
Oncology reports 2019 Feb;41(2):1169-1179
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, Gong S, Gao P, Iwakuma T, Molina-Vila MA, Chen BP, Zhang Y, Ji T, Mo Q, Chen P, Hu J, Wang S, Zhou J, Lu H, Gao Q
EBioMedicine 2019 Feb;40:92-105
EBioMedicine 2019 Feb;40:92-105
Sema4D expression and secretion are increased by HIF-1α and inhibit osteogenesis in bone metastases of lung cancer.
Chen WG, Sun J, Shen WW, Yang SZ, Zhang Y, Hu X, Qiu H, Xu SC, Chu TW
Clinical & experimental metastasis 2019 Feb;36(1):39-56
Clinical & experimental metastasis 2019 Feb;36(1):39-56
Effects of hypothermia during propofol anesthesia on learning and memory ability and hippocampal apoptosis in neonatal rats.
Liu W, Tan X, Xiong X, Yang J, Xiao X
Journal of anesthesia 2019 Feb;33(1):9-16
Journal of anesthesia 2019 Feb;33(1):9-16
Delivery of Glucosylceramidase Beta Gene Using AAV9 Vector Therapy as a Treatment Strategy in Mouse Models of Gaucher Disease.
Du S, Ou H, Cui R, Jiang N, Zhang M, Li X, Ma J, Zhang J, Ma D
Human gene therapy 2019 Feb;30(2):155-167
Human gene therapy 2019 Feb;30(2):155-167
Upregulation of miR-504-3p is associated with favorable prognosis of acute myeloid leukemia and may serve as a tumor suppressor by targeting MTHFD2.
Li SM, Zhao YQ, Hao YL, Liang YY
European review for medical and pharmacological sciences 2019 Feb;23(3):1203-1213
European review for medical and pharmacological sciences 2019 Feb;23(3):1203-1213
MiR-202-3p functions as a tumor suppressor and reduces cell migration and invasion in papillary thyroid carcinoma.
Chen J, Yin J, Liu J, Zhu RX, Zheng Y, Wang XL
European review for medical and pharmacological sciences 2019 Feb;23(3):1145-1150
European review for medical and pharmacological sciences 2019 Feb;23(3):1145-1150
Down-regulation of miR-1181 indicates a dismal prognosis for nasopharyngeal carcinoma and promoted cell proliferation and metastasis by modulating Wnt/β-catenin signaling.
Hua X, Fan KC
European review for medical and pharmacological sciences 2019 Feb;23(3):1077-1086
European review for medical and pharmacological sciences 2019 Feb;23(3):1077-1086
Liver X receptor activation reduces gastric cancer cell proliferation by suppressing Wnt signalling via LXRβ relocalization.
Wang Q, Feng F, Wang J, Ren M, Shi Z, Mao X, Zhang H, Ju X
Journal of cellular and molecular medicine 2019 Feb;23(2):789-797
Journal of cellular and molecular medicine 2019 Feb;23(2):789-797
Lysophosphatidic Acid Receptor 6 (LPAR6) Expression and Prospective Signaling Pathway Analysis in Breast Cancer.
Tao K, Guo S, Chen R, Yang C, Jian L, Yu H, Liu S
Molecular diagnosis & therapy 2019 Feb;23(1):127-138
Molecular diagnosis & therapy 2019 Feb;23(1):127-138
Lanthanum Chloride Impairs the Blood-Brain Barrier Integrity by Reduction of Junctional Proteins and Upregulation of MMP-9 in Rats.
Wu J, Yang J, Lu X, Jin C, Wu S, Zhang L, Hu X, Ma H, Cai Y
Biological trace element research 2019 Feb;187(2):482-491
Biological trace element research 2019 Feb;187(2):482-491
Paeonol-mediated apoptosis of hepatocellular carcinoma cells by NF-κB pathway.
Li Q, Zhang Y, Sun J, Bo Q
Oncology letters 2019 Feb;17(2):1761-1767
Oncology letters 2019 Feb;17(2):1761-1767
Estradiol promotes EMT in endometriosis via MALAT1/miR200s sponge function.
Du Y, Zhang Z, Xiong W, Li N, Liu H, He H, Li Q, Liu Y, Zhang L
Reproduction (Cambridge, England) 2019 Feb;157(2):179-188
Reproduction (Cambridge, England) 2019 Feb;157(2):179-188
Decreased α-tubulin acetylation induced by an acidic environment impairs autophagosome formation and leads to rat cardiomyocyte injury.
Yang L, Zhao L, Cui L, Huang Y, Ye J, Zhang Q, Jiang X, Zhang D, Huang Y
Journal of molecular and cellular cardiology 2019 Feb;127:143-153
Journal of molecular and cellular cardiology 2019 Feb;127:143-153
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
Ma H, Yang W, Zhang L, Liu S, Zhao M, Zhou G, Wang L, Jin S, Zhang Z, Hu J
British journal of cancer 2019 Feb;120(3):317-330
British journal of cancer 2019 Feb;120(3):317-330
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
Zhu L, Yang N, Du G, Li C, Liu G, Liu S, Xu Y, Di Y, Pan W, Li X
Journal of cellular biochemistry 2019 Feb;120(2):1156-1164
Journal of cellular biochemistry 2019 Feb;120(2):1156-1164
Down-regulated expressed protein HMGB3 inhibits proliferation and migration, promotes apoptosis in the placentas of fetal growth restriction.
Lv Y, Lv M, Ji X, Xue L, Rui C, Yin L, Ding H, Miao Z
The international journal of biochemistry & cell biology 2019 Feb;107:69-76
The international journal of biochemistry & cell biology 2019 Feb;107:69-76
Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos.
Ullah O, Li Z, Ali I, Xu L, Liu H, Shah SZA, Fang N
The Journal of reproduction and development 2019 Feb 8;65(1):73-81
The Journal of reproduction and development 2019 Feb 8;65(1):73-81
FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in Glioma.
He Z, Ruan X, Liu X, Zheng J, Liu Y, Liu L, Ma J, Shao L, Wang D, Shen S, Yang C, Xue Y
Journal of experimental & clinical cancer research : CR 2019 Feb 8;38(1):65
Journal of experimental & clinical cancer research : CR 2019 Feb 8;38(1):65
Scutellarin synergistically enhances cisplatin effect against ovarian cancer cells through enhancing the ability of cisplatin binding to DNA.
Xie Z, Guo Z, Lei J, Yu J
European journal of pharmacology 2019 Feb 5;844:9-16
European journal of pharmacology 2019 Feb 5;844:9-16
Caspase 3/ROCK1 pathway mediates high glucose-induced platelet microparticles shedding.
Wang GH, Ma KL, Zhang Y, Hu ZB, Liu L, Lu J, Chen PP, Lu CC, Ruan XZ, Liu BC
Biochemical and biophysical research communications 2019 Feb 5;509(2):596-602
Biochemical and biophysical research communications 2019 Feb 5;509(2):596-602
Insulin in high concentration recede cigarette smoke extract induced cellular senescence of airway epithelial cell through autophagy pathway.
Wu N, Yang D, Wu Z, Yan M, Zhang P, Liu Y
Biochemical and biophysical research communications 2019 Feb 5;509(2):498-505
Biochemical and biophysical research communications 2019 Feb 5;509(2):498-505
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Shen X, Zhong J, Yu P, Zhao Q, Huang T
Biochemical and biophysical research communications 2019 Feb 5;509(2):448-454
Biochemical and biophysical research communications 2019 Feb 5;509(2):448-454
Integrative Analysis Revealing Human Adipose-Specific Genes and Consolidating Obesity Loci.
Ahn J, Wu H, Lee K
Scientific reports 2019 Feb 28;9(1):3087
Scientific reports 2019 Feb 28;9(1):3087
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17.
Liu D, He L, Ding N, Sun W, Qiu L, Xu L, Jia A, Peng C, Zhang D, Xiang X
Bioscience reports 2019 Feb 28;39(2)
Bioscience reports 2019 Feb 28;39(2)
Taurine protected As(2)O(3)-induced the activation of hepatic stellate cells through inhibiting PPARα-autophagy pathway.
Wang Z, Tao Y, Qiu T, Yao X, Jiang L, Wang N, Wei S, Jia X, Pei P, Yang G, Liu X, Liu S, Sun X
Chemico-biological interactions 2019 Feb 25;300:123-130
Chemico-biological interactions 2019 Feb 25;300:123-130
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Li J, Hao Y, Mao W, Xue X, Xu P, Liu L, Yuan J, Zhang D, Li N, Chen H, Zhao L, Sun Z, Luo J, Chen R, Zhao RC
Journal of hematology & oncology 2019 Feb 22;12(1):19
Journal of hematology & oncology 2019 Feb 22;12(1):19
ATXN2L upregulated by epidermal growth factor promotes gastric cancer cell invasiveness and oxaliplatin resistance.
Lin L, Li X, Pan C, Lin W, Shao R, Liu Y, Zhang J, Luo Y, Qian K, Shi M, Bin J, Liao Y, Liao W
Cell death & disease 2019 Feb 20;10(3):173
Cell death & disease 2019 Feb 20;10(3):173
RNA Helicase A Is an Important Host Factor Involved in Dengue Virus Replication.
Wang Y, Chen X, Xie J, Zhou S, Huang Y, Li YP, Li X, Liu C, He J, Zhang P
Journal of virology 2019 Feb 15;93(4)
Journal of virology 2019 Feb 15;93(4)
MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer.
Xu K, Han B, Bai Y, Ma XY, Ji ZN, Xiong Y, Miao SK, Zhang YY, Zhou LM
Cell death & disease 2019 Feb 15;10(3):152
Cell death & disease 2019 Feb 15;10(3):152
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Ma Z, Cui X, Lu L, Chen G, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Stem cell research & therapy 2019 Feb 15;10(1):60
Stem cell research & therapy 2019 Feb 15;10(1):60
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Chai S, Liu K, Feng W, Liu T, Wang Q, Zhou R, Chen S, Wang L, Chen G, Ming T, Zhao J, Liu C, Xue B
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
MiR-141-3p functions as a tumor suppressor through directly targeting ZFR in non-small cell lung cancer.
Li W, Cui Y, Wang D, Wang Y, Wang L
Biochemical and biophysical research communications 2019 Feb 12;509(3):647-656
Biochemical and biophysical research communications 2019 Feb 12;509(3):647-656
MiR-223-3p functions as a tumor suppressor in lung squamous cell carcinoma by miR-223-3p-mutant p53 regulatory feedback loop.
Luo P, Wang Q, Ye Y, Zhang J, Lu D, Cheng L, Zhou H, Xie M, Wang B
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):74
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):74
LncRNA MIAT sponges miR-149-5p to inhibit efferocytosis in advanced atherosclerosis through CD47 upregulation.
Ye ZM, Yang S, Xia YP, Hu RT, Chen S, Li BW, Chen SL, Luo XY, Mao L, Li Y, Jin H, Qin C, Hu B
Cell death & disease 2019 Feb 12;10(2):138
Cell death & disease 2019 Feb 12;10(2):138
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
Li X, Xue Y, Liu X, Zheng J, Shen S, Yang C, Chen J, Li Z, Liu L, Ma J, Ma T, Liu Y
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Wang F, Jia Y, Li M, Wang L, Shao J, Guo Q, Tan S, Ding H, Chen A, Zhang F, Zheng S
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involving Nrf2.
Dong J, Li Y, Xiao H, Luo D, Zhang S, Zhu C, Jiang M, Cui M, Lu L, Fan S
Toxicology and applied pharmacology 2019 Feb 1;364:12-21
Toxicology and applied pharmacology 2019 Feb 1;364:12-21
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Meng Y, Pan M, Zheng B, Chen Y, Li W, Yang Q, Zheng Z, Sun N, Zhang Y, Li X
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, Zhao X
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization.
Velayutham TS, Kumar S, Zhang X, Kose N, Walker DH, Winslow G, Crowe JE Jr, McBride JW
Infection and immunity 2019 Dec;87(12)
Infection and immunity 2019 Dec;87(12)
Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model.
Wang J, Wan D, Wan G, Wang J, Zhang J, Zhu H
Annals of translational medicine 2019 Dec;7(23):756
Annals of translational medicine 2019 Dec;7(23):756
Epigenetic hypomethylation and upregulation of GD3s in triple negative breast cancer.
Li W, Zheng X, Ren L, Fu W, Liu J, Xv J, Liu S, Wang J, Du G
Annals of translational medicine 2019 Dec;7(23):723
Annals of translational medicine 2019 Dec;7(23):723
TRIM21 Mitigates Human Lung Microvascular Endothelial Cells' Inflammatory Responses to LPS.
Li L, Wei J, Mallampalli RK, Zhao Y, Zhao J
American journal of respiratory cell and molecular biology 2019 Dec;61(6):776-785
American journal of respiratory cell and molecular biology 2019 Dec;61(6):776-785
Oxymatrine protects against l-arginine-induced acute pancreatitis and intestine injury involving Th1/Th17 cytokines and MAPK/NF-κB signalling.
Zhang Z, Liu Q, Zang H, Shao Q, Sun T
Pharmaceutical biology 2019 Dec;57(1):595-603
Pharmaceutical biology 2019 Dec;57(1):595-603
Protective role of N-acetyl-l-tryptophan against hepatic ischemia-reperfusion injury via the RIP2/caspase-1/IL-1β signaling pathway.
Wang J, Yu S, Li J, Li H, Jiang H, Xiao P, Pan Y, Zheng J, Yu L, Jiang J
Pharmaceutical biology 2019 Dec;57(1):385-391
Pharmaceutical biology 2019 Dec;57(1):385-391
Liraglutide promotes autophagy by regulating the AMPK/mTOR pathway in a rat remnant kidney model of chronic renal failure.
Xue L, Pan Z, Yin Q, Zhang P, Zhang J, Qi W
International urology and nephrology 2019 Dec;51(12):2305-2313
International urology and nephrology 2019 Dec;51(12):2305-2313
MiR-506-3p suppresses the proliferation of ovarian cancer cells by negatively regulating the expression of MTMR6.
Wang Y, Lei X, Gao C, Xue Y, Li X, Wang H, Feng Y
Journal of biosciences 2019 Dec;44(6)
Journal of biosciences 2019 Dec;44(6)
Targeting YAP suppresses ovarian cancer progression through regulation of the PI3K/Akt/mTOR pathway.
Wei X, Jia Y, Lou H, Ma J, Huang Q, Meng Y, Sun C, Yang Z, Li X, Xu S, Yang X, Ji T, Gao Q
Oncology reports 2019 Dec;42(6):2768-2776
Oncology reports 2019 Dec;42(6):2768-2776
High concentration of chemerin caused by ovarian hyperandrogenism may lead to poor IVF outcome in polycystic ovary syndrome: a pilot study.
Wang Y, Huang R, Li X, Zhu Q, Liao Y, Tao T, Kang X, Liu W, Li S, Sun Y
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2019 Dec;35(12):1072-1077
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2019 Dec;35(12):1072-1077
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Protective effect of metformin on a rat model of lipopolysaccharide-induced preeclampsia.
Hu J, Zhang J, Zhu B
Fundamental & clinical pharmacology 2019 Dec;33(6):649-658
Fundamental & clinical pharmacology 2019 Dec;33(6):649-658
Exosomes from human-bone-marrow-derived mesenchymal stem cells protect against renal ischemia/reperfusion injury via transferring miR-199a-3p.
Zhu G, Pei L, Lin F, Yin H, Li X, He W, Liu N, Gou X
Journal of cellular physiology 2019 Dec;234(12):23736-23749
Journal of cellular physiology 2019 Dec;234(12):23736-23749
MiR-92b-3p promotes neurite growth and functional recovery via the PTEN/AKT pathway in acute spinal cord injury.
Chen Z, Li Z, Jiang C, Jiang X, Zhang J
Journal of cellular physiology 2019 Dec;234(12):23043-23052
Journal of cellular physiology 2019 Dec;234(12):23043-23052
Loss of MsrB1 perturbs spatial learning and long-term potentiation/long-term depression in mice.
Shi T, Yang Y, Zhang Z, Zhang L, Song J, Ping Y, Du X, Song G, Liu Q, Li N
Neurobiology of learning and memory 2019 Dec;166:107104
Neurobiology of learning and memory 2019 Dec;166:107104
APOBEC3A is a prominent cytidine deaminase in breast cancer.
Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA
PLoS genetics 2019 Dec;15(12):e1008545
PLoS genetics 2019 Dec;15(12):e1008545
Regional and temporal regulation and role of somatostatin receptor subtypes in the mouse brain following systemic kainate-induced acute seizures.
Iwasawa C, Narita M, Tamura H
Neuroscience research 2019 Dec;149:38-49
Neuroscience research 2019 Dec;149:38-49
Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages.
Hu Y, Gui Z, Zhou Y, Xia L, Lin K, Xu Y
Free radical biology & medicine 2019 Dec;145:146-160
Free radical biology & medicine 2019 Dec;145:146-160
Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition.
Qin S, Jiang C, Gao J
Biomedical reports 2019 Dec;11(6):241-252
Biomedical reports 2019 Dec;11(6):241-252
Nevirapine inhibits migration and invasion in dedifferentiated thyroid cancer cells.
Shang H, Zhao J, Yao J, Wang H, Wang S, Dong J, Liao L
Thoracic cancer 2019 Dec;10(12):2243-2252
Thoracic cancer 2019 Dec;10(12):2243-2252
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Guo Y, Wu J, Xie K, Tan J, Yang Y, Zhao S, Wang L, Jiang W, Hao Y
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
Overexpressed ITGA2 promotes malignant tumor aggression by up-regulating PD-L1 expression through the activation of the STAT3 signaling pathway.
Ren D, Zhao J, Sun Y, Li D, Meng Z, Wang B, Fan P, Liu Z, Jin X, Wu H
Journal of experimental & clinical cancer research : CR 2019 Dec 9;38(1):485
Journal of experimental & clinical cancer research : CR 2019 Dec 9;38(1):485
Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis.
Chou CW, Lin CH, Hsiao TH, Lo CC, Hsieh CY, Huang CC, Sher YP
Scientific reports 2019 Dec 31;9(1):20403
Scientific reports 2019 Dec 31;9(1):20403
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
Gao H, Zhang J, Ren X
Bioscience reports 2019 Dec 20;39(12)
Bioscience reports 2019 Dec 20;39(12)
Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation.
Sun H, Zhang F, Xu Y, Sun S, Wang H, Du Q, Gu C, Black SM, Han Y, Tang H
Antioxidants & redox signaling 2019 Dec 20;31(18):1352-1370
Antioxidants & redox signaling 2019 Dec 20;31(18):1352-1370
Enterovirus 71 VP1 Protein Regulates Viral Replication in SH-SY5Y Cells via the mTOR Autophagy Signaling Pathway.
Liu ZW, Zhuang ZC, Chen R, Wang XR, Zhang HL, Li SH, Wang ZY, Wen HL
Viruses 2019 Dec 20;12(1)
Viruses 2019 Dec 20;12(1)
Biosynthetic CircRNA_001160 induced by PTBP1 regulates the permeability of BTB via the CircRNA_001160/miR-195-5p/ETV1 axis.
Li H, Shen S, Ruan X, Liu X, Zheng J, Liu Y, Yang C, Wang D, Liu L, Ma J, Ma T, Wang P, Cai H, Li Z, Zhao L, Xue Y
Cell death & disease 2019 Dec 20;10(12):960
Cell death & disease 2019 Dec 20;10(12):960
Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.
Huang CM, Huang CS, Hsu TN, Huang MS, Fong IH, Lee WH, Liu SC
Cells 2019 Dec 18;9(1)
Cells 2019 Dec 18;9(1)
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.
Zhao Y, Lee CK, Lin CH, Gassen RB, Xu X, Huang Z, Xiao C, Bonorino C, Lu LF, Bui JD, Hui E
Immunity 2019 Dec 17;51(6):1059-1073.e9
Immunity 2019 Dec 17;51(6):1059-1073.e9
Graphene Quantum Dots Induce Autophagy and Reveal Protection Against Hydrogen Peroxide-Induced Oxidative Stress Injury.
Hua S, Yang L, Gao T, Jiang P, Jiang F, Liu Y
ACS applied bio materials 2019 Dec 16;2(12):5760-5768
ACS applied bio materials 2019 Dec 16;2(12):5760-5768
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, Feng J
Life sciences 2019 Dec 15;239:117020
Life sciences 2019 Dec 15;239:117020
Gestational B-vitamin supplementation alleviates PM(2.5)-induced autism-like behavior and hippocampal neurodevelopmental impairment in mice offspring.
Wang T, Zhang T, Sun L, Li W, Zhang C, Yu L, Guan Y
Ecotoxicology and environmental safety 2019 Dec 15;185:109686
Ecotoxicology and environmental safety 2019 Dec 15;185:109686
Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation.
Tan G, Yi Z, Song H, Xu F, Li F, Aliyari R, Zhang H, Du P, Ding Y, Niu J, Wang X, Su L, Qin FX, Cheng G
Cell reports 2019 Dec 10;29(11):3551-3563.e3
Cell reports 2019 Dec 10;29(11):3551-3563.e3
DACT1 Involvement in the Cytoskeletal Arrangement of Cardiomyocytes in Atrial Fibrillation by Regulating Cx43.
Hou J, Yue Y, Hu B, Xu G, Su R, Lv L, Huang J, Yao J, Guan Y, Wang K, Wu Z
Brazilian journal of cardiovascular surgery 2019 Dec 1;34(6):711-722
Brazilian journal of cardiovascular surgery 2019 Dec 1;34(6):711-722
COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats.
Song Q, Feng YB, Wang L, Shen J, Li Y, Fan C, Wang P, Yu SY
Neuropharmacology 2019 Dec 1;160:107779
Neuropharmacology 2019 Dec 1;160:107779
Potential role of microRNA-424 in regulating ERRγ to suppress trophoblast proliferation and invasion in fetal growth restriction.
Zou Z, He Z, Cai J, Huang L, Zhu H, Luo Y
Placenta 2019 Aug;83:57-62
Placenta 2019 Aug;83:57-62
Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts.
Lu Y, Zhou Q, Lu JW, Wang WS, Sun K
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Aug;82(2):e13150
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Aug;82(2):e13150
Effects of antisense lncRNA PCBP1-AS1 on biological behaviors of vulvar squamous carcinoma cells by regulating TRAF5 and NF-κB expression.
Wang H, Ouyang L, Gao S
Translational cancer research 2019 Aug;8(4):1578-1590
Translational cancer research 2019 Aug;8(4):1578-1590
hnRNPM, a potential mediator of YY1 in promoting the epithelial-mesenchymal transition of prostate cancer cells.
Yang T, An Z, Zhang C, Wang Z, Wang X, Liu Y, Du E, Liu R, Zhang Z, Xu Y
The Prostate 2019 Aug;79(11):1199-1210
The Prostate 2019 Aug;79(11):1199-1210
Sequential application of bFGF and BMP-2 facilitates osteogenic differentiation of human periodontal ligament stem cells.
Kang W, Liang Q, Du L, Shang L, Wang T, Ge S
Journal of periodontal research 2019 Aug;54(4):424-434
Journal of periodontal research 2019 Aug;54(4):424-434
Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery.
Yadavalli T, Ames J, Agelidis A, Suryawanshi R, Jaishankar D, Hopkins J, Thakkar N, Koujah L, Shukla D
Science advances 2019 Aug;5(8):eaax0780
Science advances 2019 Aug;5(8):eaax0780
Tizanidine hydrochloride exhibits a cytotoxic effect on osteosarcoma cells through the PI3K/AKT signaling pathway.
Xing XW, Sun YF, Zhao J, Pan ZX, Jiang WX
The Journal of international medical research 2019 Aug;47(8):3792-3802
The Journal of international medical research 2019 Aug;47(8):3792-3802
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Betharia S, Rondόn-Ortiz AN, Brown DA
Neurochemical research 2019 Aug;44(8):1878-1892
Neurochemical research 2019 Aug;44(8):1878-1892
CHD1L is associated with poor survival and promotes the proliferation and metastasis of intrahepatic cholangiocarcinoma.
Li S, Chai Y, Ding Y, Yuan T, Wu C, Huang C
Oncology reports 2019 Aug;42(2):657-669
Oncology reports 2019 Aug;42(2):657-669
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Zhan L, Liu D, Wen H, Hu J, Pang T, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
Mutation in NPPA causes atrial fibrillation by activating inflammation and cardiac fibrosis in a knock-in rat model.
Cheng C, Liu H, Tan C, Tong D, Zhao Y, Liu X, Si W, Wang L, Liang L, Li J, Wang C, Chen Q, Du Y, Wang QK, Ren X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):8878-8891
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):8878-8891
LncRNA MAGI2-AS3 inhibits hepatocellular carcinoma cell proliferation and migration by targeting the miR-374b-5p/SMG1 signaling pathway.
Yin Z, Ma T, Yan J, Shi N, Zhang C, Lu X, Hou B, Jian Z
Journal of cellular physiology 2019 Aug;234(10):18825-18836
Journal of cellular physiology 2019 Aug;234(10):18825-18836
Reduced PDGF-AA in subchondral bone leads to articular cartilage degeneration after strenuous running.
Yao Z, Chen P, Wang S, Deng G, Hu Y, Lin Q, Zhang X, Yu B
Journal of cellular physiology 2019 Aug;234(10):17946-17958
Journal of cellular physiology 2019 Aug;234(10):17946-17958
Long noncoding RNA SOX21-AS1 promotes cervical cancer progression by competitively sponging miR-7/VDAC1.
Zhang X, Zhao X, Li Y, Zhou Y, Zhang Z
Journal of cellular physiology 2019 Aug;234(10):17494-17504
Journal of cellular physiology 2019 Aug;234(10):17494-17504
Long non-coding RNA LINC00526 represses glioma progression via forming a double negative feedback loop with AXL.
Yan J, Xu C, Li Y, Tang B, Xie S, Hong T, Zeng E
Journal of cellular and molecular medicine 2019 Aug;23(8):5518-5531
Journal of cellular and molecular medicine 2019 Aug;23(8):5518-5531
The Expression of MBD6 Is Associated with Tumor Size in Uterine Leiomyomas.
Liang MR, Zeng Y, Zeng SY, Zhang JW, Yang BC, Zhang ZY, Liu FY, Luo Y, Zou Y, Wang F, Huang OP
Genetic testing and molecular biomarkers 2019 Aug;23(8):523-532
Genetic testing and molecular biomarkers 2019 Aug;23(8):523-532
Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway.
Zong Z, Song Y, Xue Y, Ruan X, Liu X, Yang C, Zheng J, Cao S, Li Z, Liu Y
Journal of cellular and molecular medicine 2019 Aug;23(8):5048-5062
Journal of cellular and molecular medicine 2019 Aug;23(8):5048-5062
MiR-543-5p inhibits inflammation and promotes nerve regeneration through inactivation of the NF-κB in rats after spinal cord injury.
Zhao CL, Cui HA, Zhang XR
European review for medical and pharmacological sciences 2019 Aug;23(3 Suppl):39-46
European review for medical and pharmacological sciences 2019 Aug;23(3 Suppl):39-46
Upregulation of miR‑95-3p inhibits growth of osteosarcoma by targeting HDGF.
Liu X, Ma W, Ma J, Xiao L, Hao D
Pathology, research and practice 2019 Aug;215(8):152492
Pathology, research and practice 2019 Aug;215(8):152492
IDH2 compensates for IDH1 mutation to maintain cell survival under hypoxic conditions in IDH1‑mutant tumor cells.
Zhang Y, Lv W, Li Q, Wang Q, Ru Y, Xiong X, Yan F, Pan T, Lin W, Li X
Molecular medicine reports 2019 Aug;20(2):1893-1900
Molecular medicine reports 2019 Aug;20(2):1893-1900
Potential role of the cAMP/PKA/CREB signalling pathway in hypoxic preconditioning and effect on propofol‑induced neurotoxicity in the hippocampus of neonatal rats.
Guan R, Lv J, Xiao F, Tu Y, Xie Y, Li L
Molecular medicine reports 2019 Aug;20(2):1837-1845
Molecular medicine reports 2019 Aug;20(2):1837-1845
SDF1/CXCR4 axis plays a role in angiogenesis during the degeneration of intervertebral discs.
Zhang H, He B
Molecular medicine reports 2019 Aug;20(2):1203-1211
Molecular medicine reports 2019 Aug;20(2):1203-1211
MicroRNA-338-3p suppresses cell proliferation, migration and invasion in human malignant melanoma by targeting MACC1.
Zhang C, Li H, Wang J, Zhang J, Hou X
Experimental and therapeutic medicine 2019 Aug;18(2):997-1004
Experimental and therapeutic medicine 2019 Aug;18(2):997-1004
Oxaliplatin reverses the GLP-1R-mediated promotion of intrahepatic cholangiocarcinoma by altering FoxO1 signaling.
Chen B, Zhou W, Zhao W, Yuan P, Tang C, Wang G, Leng J, Ma J, Wang X, Hui Y, Wang Q
Oncology letters 2019 Aug;18(2):1989-1998
Oncology letters 2019 Aug;18(2):1989-1998
Curcumin suppresses intestinal microvascular endothelial cells invasion and angiogenesis induced by activated platelets.
Xu S, Xu ZX, Yan S, Le J, Chen H, Ming L, Xu SG, Lin T
Experimental and therapeutic medicine 2019 Aug;18(2):1099-1106
Experimental and therapeutic medicine 2019 Aug;18(2):1099-1106
MicroRNA-23b-3p promotes the proliferation, migration, and epithelial-mesenchymal transition of lens epithelial cells by targeting Sprouty2.
Liu W, Yang Y, Yan J, Wang L
Acta histochemica 2019 Aug;121(6):704-711
Acta histochemica 2019 Aug;121(6):704-711
UFL1 modulates NLRP3 inflammasome activation and protects against pyroptosis in LPS-stimulated bovine mammary epithelial cells.
Li C, Wang X, Kuang M, Li L, Wang Y, Yang F, Wang G
Molecular immunology 2019 Aug;112:1-9
Molecular immunology 2019 Aug;112:1-9
IgE Aggravates the Senescence of Smooth Muscle Cells in Abdominal Aortic Aneurysm by Upregulating LincRNA-p21.
Guo W, Gao R, Zhang W, Ge W, Ren M, Li B, Zhao H, Wang J
Aging and disease 2019 Aug;10(4):699-710
Aging and disease 2019 Aug;10(4):699-710
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
Pan T, Song Z, Wu L, Liu G, Ma X, Peng Z, Zhou M, Liang L, Liu B, Liu J, Zhang J, Zhang X, Huang R, Zhao J, Li Y, Ling X, Luo Y, Tang X, Cai W, Deng K, Li L, Zhang H
eLife 2019 Aug 9;8
eLife 2019 Aug 9;8
miR-448 targets IDO1 and regulates CD8(+) T cell response in human colon cancer.
Lou Q, Liu R, Yang X, Li W, Huang L, Wei L, Tan H, Xiang N, Chan K, Chen J, Liu H
Journal for immunotherapy of cancer 2019 Aug 7;7(1):210
Journal for immunotherapy of cancer 2019 Aug 7;7(1):210
Ginsenoside compound K ameliorates imiquimod-induced psoriasis-like dermatitis through inhibiting REG3A/RegIIIγ expression in keratinocytes.
Fan H, Wang Y, Zhang X, Chen J, Zhou Q, Yu Z, Chen Y, Chen Z, Gu J, Shi Y
Biochemical and biophysical research communications 2019 Aug 6;515(4):665-671
Biochemical and biophysical research communications 2019 Aug 6;515(4):665-671
Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway.
Ming-Yan Y, Jing Z, Shu-Qin G, Xiao-Liang B, Zhi-Hong L, Xue Z
Bioscience reports 2019 Aug 30;39(8)
Bioscience reports 2019 Aug 30;39(8)
Verification of osteoblast differentiation on airborne-particle abrasion, large-grit, acid-etched surface of titanium implants regulated by yes-associated protein and transcriptional coactivator with PDZ-binding motif.
Wei T, Li J, Sun H, Jiang M, Yang Y, Luo X, Liu T
Journal of oral science 2019 Aug 28;61(3):431-440
Journal of oral science 2019 Aug 28;61(3):431-440
PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis.
Jiang Y, Liu F, Zou F, Zhang Y, Wang B, Zhang Y, Lian A, Han X, Liu Z, Liu X, Jin M, Wang D, Li G, Liu J
Stem cell research & therapy 2019 Aug 23;10(1):268
Stem cell research & therapy 2019 Aug 23;10(1):268
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Wang Z, Liang M, Li H, Cai L, He H, Wu Q, Yang L
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
Huang Z, Xu J, Huang X, Sun G, Jiang R, Wu H, Shan X, Bao K, Wu Q, Wu H, Tao W
European journal of pharmacology 2019 Aug 15;857:172424
European journal of pharmacology 2019 Aug 15;857:172424
Overexpression of RACK1 enhanced the replication of porcine reproductive and respiratory syndrome virus in Marc-145 cells and promoted the NF-κB activation via upregulating the expression and phosphorylation of TRAF2.
Liu X, Bi J, Zhao Q, Li M, Zuo Q, Wang X, Lan R, Li X, Yang G, Liu J, Yin G
Gene 2019 Aug 15;709:75-83
Gene 2019 Aug 15;709:75-83
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Wu T, Jiang N, Ji Z, Shi G
Life sciences 2019 Aug 15;231:116569
Life sciences 2019 Aug 15;231:116569
HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress.
Wang Y, Yang C, Elsheikh NAH, Li C, Yang F, Wang G, Li L
Aging 2019 Aug 12;11(15):5535-5547
Aging 2019 Aug 12;11(15):5535-5547
Interferon regulatory factor-1 reverses chemoresistance by downregulating the expression of P-glycoprotein in gastric cancer.
Yuan J, Yin Z, Tan L, Zhu W, Tao K, Wang G, Shi W, Gao J
Cancer letters 2019 Aug 10;457:28-39
Cancer letters 2019 Aug 10;457:28-39
Exogenous H(2)S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD(+)-SIRT3 pathway in cardiac tissues of db/db mice.
Sun Y, Teng Z, Sun X, Zhang L, Chen J, Wang B, Lu F, Liu N, Yu M, Peng S, Wang Y, Zhao D, Zhao Y, Ren H, Cheng Z, Dong S, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2019 Aug 1;317(2):E284-E297
American journal of physiology. Endocrinology and metabolism 2019 Aug 1;317(2):E284-E297
Identification of proteomic signatures associated with COPD frequent exacerbators.
Sun P, Ye R, Wang C, Bai S, Zhao L
Life sciences 2019 Aug 1;230:1-9
Life sciences 2019 Aug 1;230:1-9
Titania nanotubes promote osteogenesis via mediating crosstalk between macrophages and MSCs under oxidative stress.
Shen X, Yu Y, Ma P, Luo Z, Hu Y, Li M, He Y, Zhang Y, Peng Z, Song G, Cai K
Colloids and surfaces. B, Biointerfaces 2019 Aug 1;180:39-48
Colloids and surfaces. B, Biointerfaces 2019 Aug 1;180:39-48
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2019 Aug 1;10(8):5240-5241
Food & function 2019 Aug 1;10(8):5240-5241
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Li X, Huang Y, Wang P, Song W, Yao Q, Hu Q, Zhou S
Translational cancer research 2019 Apr;8(2):402-409
Translational cancer research 2019 Apr;8(2):402-409
STAG2 loss-of-function mutation induces PD-L1 expression in U2OS cells.
Nie Z, Gao W, Zhang Y, Hou Y, Liu J, Li Z, Xue W, Ye X, Jin A
Annals of translational medicine 2019 Apr;7(7):127
Annals of translational medicine 2019 Apr;7(7):127
IL-37 attenuates allergic process via STAT6/STAT3 pathways in murine allergic rhinitis.
Wang J, Shen Y, Li C, Liu C, Wang ZH, Li YS, Ke X, Hu GH
International immunopharmacology 2019 Apr;69:27-33
International immunopharmacology 2019 Apr;69:27-33
Uridine-cytidine kinase 2 upregulation predicts poor prognosis of hepatocellular carcinoma and is associated with cancer aggressiveness.
Huang S, Li J, Tam NL, Sun C, Hou Y, Hughes B, Wang Z, Zhou Q, He X, Wu L
Molecular carcinogenesis 2019 Apr;58(4):603-615
Molecular carcinogenesis 2019 Apr;58(4):603-615
Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells.
Li H, Dai Y, Luo Z, Nie D
Molecular biology reports 2019 Apr;46(2):2029-2038
Molecular biology reports 2019 Apr;46(2):2029-2038
Baicalin induced colon cancer cells apoptosis through miR-217/DKK1-mediated inhibition of Wnt signaling pathway.
Jia Y, Chen L, Guo S, Li Y
Molecular biology reports 2019 Apr;46(2):1693-1700
Molecular biology reports 2019 Apr;46(2):1693-1700
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
Di X, He G, Chen H, Zhu C, Qin Q, Yan J, Zhang X, Sun X
Journal of gastroenterology and hepatology 2019 Apr;34(4):728-735
Journal of gastroenterology and hepatology 2019 Apr;34(4):728-735
The orphan nuclear receptor RORα is a potential endogenous protector in renal ischemia/reperfusion injury.
Cai J, Jiao X, Fang Y, Yu X, Ding X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5704-5715
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5704-5715
Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro.
Jing Z, Wang C, Yang Q, Wei X, Jin Y, Meng Q, Liu Q, Liu Z, Ma X, Liu K, Sun H, Liu M
Journal of cellular physiology 2019 Apr;234(4):4472-4490
Journal of cellular physiology 2019 Apr;234(4):4472-4490
Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P-glycoprotein.
Sun Y, Liu W, Wang C, Meng Q, Liu Z, Huo X, Yang X, Sun P, Sun H, Ma X, Peng J, Liu K
Journal of cellular physiology 2019 Apr;234(4):3685-3696
Journal of cellular physiology 2019 Apr;234(4):3685-3696
NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats.
Chen L, He PL, Yang J, Yang YF, Wang K, Amend B, Stenzl A, Zhang YM, Wang ZL, Xing SS, Luo X
Molecular medicine reports 2019 Apr;19(4):2960-2968
Molecular medicine reports 2019 Apr;19(4):2960-2968
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina.
Badiei A, Sudharsan R, Santana E, Dunaief JL, Aguirre GD
Experimental eye research 2019 Apr;181:72-84
Experimental eye research 2019 Apr;181:72-84
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, Sun H, Qi Y, Fang L, Liu K, Peng J
British journal of pharmacology 2019 Apr;176(7):919-937
British journal of pharmacology 2019 Apr;176(7):919-937
The long noncoding RNA TPTE2P1 promotes the viability of colorectal cancer cells.
Dai X, Xie Y, Dong M, Zhao J, Yu H, Zhou B, Xu Y, Yu Y, Cao Y, Zhang Y
Journal of cellular biochemistry 2019 Apr;120(4):5268-5276
Journal of cellular biochemistry 2019 Apr;120(4):5268-5276
MicroRNA-129-1-3p regulates cyclic stretch-induced endothelial progenitor cell differentiation by targeting Runx2.
Li N, Wang WB, Bao H, Shi Q, Jiang ZL, Qi YX, Han Y
Journal of cellular biochemistry 2019 Apr;120(4):5256-5267
Journal of cellular biochemistry 2019 Apr;120(4):5256-5267
Metabolic Profiling of Tumors, Sera, and Skeletal Muscles from an Orthotopic Murine Model of Gastric Cancer Associated-Cachexia.
Cui P, Huang C, Guo J, Wang Q, Liu Z, Zhuo H, Lin D
Journal of proteome research 2019 Apr 5;18(4):1880-1892
Journal of proteome research 2019 Apr 5;18(4):1880-1892
A fixation method for the optimisation of western blotting.
Xu J, Sun H, Huang G, Liu G, Li Z, Yang H, Jin L, Cui X, Shi L, Ma T, Kameyama A, Dong W
Scientific reports 2019 Apr 30;9(1):6649
Scientific reports 2019 Apr 30;9(1):6649
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
Guo HH, Feng CL, Zhang WX, Luo ZG, Zhang HJ, Zhang TT, Ma C, Zhan Y, Li R, Wu S, Abliz Z, Li C, Li XL, Ma XL, Wang LL, Zheng WS, Han YX, Jiang JD
Nature communications 2019 Apr 30;10(1):1981
Nature communications 2019 Apr 30;10(1):1981
Long non-coding RNA LOC284454 promotes migration and invasion of nasopharyngeal carcinoma via modulating the Rho/Rac signaling pathway.
Fan C, Tang Y, Wang J, Wang Y, Xiong F, Zhang S, Li X, Xiang B, Wu X, Guo C, Ma J, Zhou M, Li X, Xiong W, Li Y, Li G, Zeng Z
Carcinogenesis 2019 Apr 29;40(2):380-391
Carcinogenesis 2019 Apr 29;40(2):380-391
Hepatitis C Virus-Induced FUT8 Causes 5-FU Drug Resistance in Human Hepatoma Huh7.5.1 Cells.
Li S, Liu XY, Pan Q, Wu J, Liu ZH, Wang Y, Liu M, Zhang XL
Viruses 2019 Apr 24;11(4)
Viruses 2019 Apr 24;11(4)
The Shigella type three secretion system effector OspF invades host nucleus by binding host importin α1.
Zhao H, Zhang Y, Wu P, Wang J, Li H
World journal of microbiology & biotechnology 2019 Apr 22;35(5):71
World journal of microbiology & biotechnology 2019 Apr 22;35(5):71
Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27.
Li B, Sun C, Sun J, Yang MH, Zuo R, Liu C, Lan WR, Liu MH, Huang B, Zhou Y
Stem cell research & therapy 2019 Apr 15;10(1):118
Stem cell research & therapy 2019 Apr 15;10(1):118
Zinc-finger protein YY1 suppresses tumor growth of human nasopharyngeal carcinoma by inactivating c-Myc-mediated microRNA-141 transcription.
Li M, Liu Y, Wei Y, Wu C, Meng H, Niu W, Zhou Y, Wang H, Wen Q, Fan S, Li Z, Li X, Zhou J, Cao K, Xiong W, Zeng Z, Li X, Qiu Y, Li G, Zhou M
The Journal of biological chemistry 2019 Apr 12;294(15):6172-6187
The Journal of biological chemistry 2019 Apr 12;294(15):6172-6187
Epigallocatechin-3-gallate inhibits angiotensin II-induced cardiomyocyte hypertrophy via regulating Hippo signaling pathway in H9c2 rat cardiomyocytes.
Ma Y, Hu Y, Wu J, Wen J, Li S, Zhang L, Zhang J, Li Y, Li J
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):422-430
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):422-430
Renalase attenuates mitochondrial fission in cisplatin-induced acute kidney injury via modulating sirtuin-3.
Huang Z, Li Q, Yuan Y, Zhang C, Wu L, Liu X, Cao W, Guo H, Duan S, Xu X, Zhang B, Xing C
Life sciences 2019 Apr 1;222:78-87
Life sciences 2019 Apr 1;222:78-87
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Fan J, Chen M, Wang X, Tian Z, Wang J, Fan D, Zeng J, Zhang K, Dai X
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Chen DQ, Cao G, Chen H, Argyopoulos CP, Yu H, Su W, Chen L, Samuels DC, Zhuang S, Bayliss GP, Zhao S, Yu XY, Vaziri ND, Wang M, Liu D, Mao JR, Ma SX, Zhao J, Zhang Y, Shang YQ, Kang H, Ye F, Cheng XH, Li XR, Zhang L, Meng MX, Guo Y, Zhao YY
Nature communications 2019 Apr 1;10(1):1476
Nature communications 2019 Apr 1;10(1):1476
S100A4-MYH9 Axis Promote Migration and Invasion of Gastric Cancer Cells by Inducing TGF-β-Mediated Epithelial-Mesenchymal Transition.
Li F, Shi J, Xu Z, Yao X, Mou T, Yu J, Liu H, Li G
Journal of Cancer 2018;9(21):3839-3849
Journal of Cancer 2018;9(21):3839-3849
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Duan YM, Jin Y, Guo ML, Duan LX, Wang JG
Journal of Cancer 2018;9(15):2723-2733
Journal of Cancer 2018;9(15):2723-2733
A Chinese Herbal Formula Ameliorates Pulmonary Fibrosis by Inhibiting Oxidative Stress via Upregulating Nrf2.
Bai Y, Li J, Zhao P, Li Y, Li M, Feng S, Qin Y, Tian Y, Zhou T
Frontiers in pharmacology 2018;9:628
Frontiers in pharmacology 2018;9:628
MAPK Phosphatase-1 Deficiency Exacerbates the Severity of Imiquimod-Induced Psoriasiform Skin Disease.
Zhao W, Xiao S, Li H, Zheng T, Huang J, Hu R, Zhang B, Liu X, Huang G
Frontiers in immunology 2018;9:569
Frontiers in immunology 2018;9:569
Bacillus amyloliquefaciens Ameliorates Dextran Sulfate Sodium-Induced Colitis by Improving Gut Microbial Dysbiosis in Mice Model.
Cao G, Wang K, Li Z, Tao F, Xu Y, Lan J, Chen G, Yang C
Frontiers in microbiology 2018;9:3260
Frontiers in microbiology 2018;9:3260
Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx.
Tan G, Xu F, Song H, Yuan Y, Xiao Q, Ma F, Qin FX, Cheng G
Frontiers in immunology 2018;9:1872
Frontiers in immunology 2018;9:1872
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, Mei S, Zhu X, Yu J, Kijlstra A, Yang P, Hou S
Frontiers in immunology 2018;9:1713
Frontiers in immunology 2018;9:1713
β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial-Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling.
Cao ZQ, Wang XX, Lu L, Xu JW, Li XB, Zhang GR, Ma ZJ, Shi AC, Wang Y, Song YJ
Frontiers in pharmacology 2018;9:1525
Frontiers in pharmacology 2018;9:1525
Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.
Liu XY, Xu HX, Li JK, Zhang D, Ma XH, Huang LN, Lü JH, Wang XZ
Frontiers in physiology 2018;9:102
Frontiers in physiology 2018;9:102
CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription.
Huang S, Chi Y, Qin Y, Wang Z, Xiu B, Su Y, Guo R, Guo L, Sun H, Zeng C, Zhou S, Hu X, Liu S, Shao Z, Wu Z, Jin W, Wu J
Theranostics 2018;8(9):2549-2564
Theranostics 2018;8(9):2549-2564
The lncKLF6/KLF6 feedback loop regulates the growth of non-small cell lung cancer.
Li F, Zhang Q, Gong Y, Yu J
American journal of cancer research 2018;8(8):1427-1439
American journal of cancer research 2018;8(8):1427-1439
CDC20 regulates cardiac hypertrophy via targeting LC3-dependent autophagy.
Xie YP, Lai S, Lin QY, Xie X, Liao JW, Wang HX, Tian C, Li HH
Theranostics 2018;8(21):5995-6007
Theranostics 2018;8(21):5995-6007
Protective Role of Nuclear Factor-Erythroid 2-Related Factor 2 Against Radiation-Induced Lung Injury and Inflammation.
Tian X, Wang F, Luo Y, Ma S, Zhang N, Sun Y, You C, Tang G, Li S, Gong Y, Xie C
Frontiers in oncology 2018;8:542
Frontiers in oncology 2018;8:542
SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.
Li P, Jin Y, Qi F, Wu F, Luo S, Cheng Y, Montgomery RR, Qian F
Frontiers in cellular and infection microbiology 2018;8:113
Frontiers in cellular and infection microbiology 2018;8:113
Hypoxia-induced hyperpermeability of rat glomerular endothelial cells involves HIF-2α mediated changes in the expression of occludin and ZO-1.
Luo PL, Wang YJ, Yang YY, Yang JJ
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2018;51(7):e6201
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2018;51(7):e6201
Long-Noncoding RNA Colorectal Neoplasia Differentially Expressed Gene as a Potential Target to Upregulate the Expression of IRX5 by miR-136-5P to Promote Oncogenic Properties in Hepatocellular Carcinoma.
Zhu L, Liu Y, Chen Q, Yu G, Chen J, Chen K, Yang N, Zeng T, Yan S, Huang A, Tang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2229-2248
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2229-2248
β-Arrestin2 Inhibits Expression of Inflammatory Cytokines in BEAS-2B Lung Epithelial Cells Treated with Cigarette Smoke Condensate via Inhibition of Autophagy.
Wu Y, Li Y, Wu B, Tan C, He X, Xu B, Yu G, Wang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1270-1285
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1270-1285
Curcumin Inhibits Polyethylene-Induced Osteolysis via Repressing NF-κB Signaling Pathway Activation.
An S, Han F, Hu Y, Liu Y, Li J, Wang L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(3):1100-1112
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(3):1100-1112
Transient High-Glucose Stimulation Induces Persistent Inflammatory Factor Secretion from Rat Glomerular Mesangial Cells via an Epigenetic Mechanism.
Yunlei D, Qiuling F, Xu W, Qianwen Z, Xu C, Li X, Lining W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(5):1747-1754
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(5):1747-1754
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
Peng X, Kang Q, Wan R, Wang Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
Overexpression of Toll-Like Receptor 4 Contributes to Phagocytosis of Salmonella Enterica Serovar Typhimurium via Phosphoinositide 3-Kinase Signaling in Sheep.
Wang S, Deng S, Cao Y, Zhang R, Wang Z, Jiang X, Wang J, Zhang X, Zhang J, Liu G, Lian Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(2):662-677
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(2):662-677
CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8.
Liu J, Wang D, Long Z, Liu J, Li W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):173-184
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):173-184
Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis.
Yang Y, Guan J, Shaikh AS, Liang Y, Sun L, Wang M, Li D, Qiu C, Li X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):2159-2169
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):2159-2169
TIFA Promotes Cell Survival and Migration in Lung Adenocarcinoma.
Men W, Li W, Zhao J, Li Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):2097-2108
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):2097-2108
A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains.
Yan W, Long P, Chen T, Liu W, Yao L, Ren Z, Li X, Wang J, Xue J, Tao Y, Zhang L, Zhang Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1883-1897
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1883-1897
Allograft Inflammatory Factor-1 Mediates Macrophage-Induced Impairment of Insulin Signaling in Adipocytes.
Ren J, Lin Y, Tang J, Yue H, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):403-413
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):403-413
RIP140/PGC-1α axis involved in vitamin A-induced neural differentiation by increasing mitochondrial function.
Mu Q, Yu W, Zheng S, Shi H, Li M, Sun J, Wang D, Hou X, Liu L, Wang X, Zhao Z, Liang R, Zhang X, Dong W, Zeng C, Guo J
Artificial cells, nanomedicine, and biotechnology 2018;46(sup1):806-816
Artificial cells, nanomedicine, and biotechnology 2018;46(sup1):806-816
Renal Denervation Effects on Myocardial Fibrosis and Ventricular Arrhythmias in Rats with Ischemic Cardiomyopathy.
Zhang B, Li X, Chen C, Jiang W, Lu D, Liu Q, Wang K, Yan Y, Jiang Z, Geng J, Xu H, Shan Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2471-2479
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2471-2479
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Zheng Q, Zhou F, Cui X, Liu M, Li Y, Liu S, Tan J, Yan Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2297-2310
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2297-2310
MicroRNA-223 Regulates Cardiac Fibrosis After Myocardial Infarction by Targeting RASA1.
Liu X, Xu Y, Deng Y, Li H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1439-1454
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1439-1454
Lipocalin 2 Suppresses Ocular Inflammation by Inhibiting the Activation of NF-κβ Pathway in Endotoxin-Induced Uveitis.
Tang W, Ma J, Gu R, Ding X, Lei B, Wang X, Zhuang H, Xu G
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(1):375-388
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(1):375-388
Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway.
Feng H, Li Z, Du J, Sun J, Feng W, Li D, Liu S, Wang W, Liu H, Amizuka N, Li M
Cell death discovery 2018;4:47
Cell death discovery 2018;4:47
abLIM1 constructs non-erythroid cortical actin networks to prevent mechanical tension-induced blebbing.
Li G, Huang S, Yang S, Wang J, Cao J, Czajkowsky DM, Shao Z, Zhu X
Cell discovery 2018;4:42
Cell discovery 2018;4:42
MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1.
Tian ZQ, Jiang H, Lu ZB
Cellular & molecular biology letters 2018;23:41
Cellular & molecular biology letters 2018;23:41
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Zhang GY, Lu D, Duan SF, Gao YR, Liu SY, Hong Y, Dong PZ, Chen YG, Li T, Wang DY, Cheng XS, He F, Wei JS, Li GY, Zhang QY, Wu DD, Ji XY
Oxidative medicine and cellular longevity 2018;2018:9647809
Oxidative medicine and cellular longevity 2018;2018:9647809
Resveratrol Inhibits the TGF-β1-Induced Proliferation of Cardiac Fibroblasts and Collagen Secretion by Downregulating miR-17 in Rat.
Zhang Y, Lu Y, Ong'achwa MJ, Ge L, Qian Y, Chen L, Hu X, Li F, Wei H, Zhang C, Li C, Wang Z
BioMed research international 2018;2018:8730593
BioMed research international 2018;2018:8730593
Estradiol Alleviates Intervertebral Disc Degeneration through Modulating the Antioxidant Enzymes and Inhibiting Autophagy in the Model of Menopause Rats.
Jin LY, Lv ZD, Wang K, Qian L, Song XX, Li XF, Shen HX
Oxidative medicine and cellular longevity 2018;2018:7890291
Oxidative medicine and cellular longevity 2018;2018:7890291
γδT Cells Exacerbate Podocyte Injury via the CD28/B7-1-Phosphor-SRC Kinase Pathway.
Chen W, Wu Y, Zhang G, Wang M, Yang H, Li Q
BioMed research international 2018;2018:5647120
BioMed research international 2018;2018:5647120
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
Zhao M, Zhang X, Gao L, Song Y, Xu C, Yu C, Shao S, Zhao J
International journal of endocrinology 2018;2018:4215848
International journal of endocrinology 2018;2018:4215848
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T
Oxidative medicine and cellular longevity 2018;2018:3853409
Oxidative medicine and cellular longevity 2018;2018:3853409
Proteomic Profile of Carbonylated Proteins Screen Regulation of Apoptosis via CaMK Signaling in Response to Regular Aerobic Exercise.
Liu W, Li L, Kuang H, Xia Y, Wang Z, Liu S, Yin D
BioMed research international 2018;2018:2828143
BioMed research international 2018;2018:2828143
Hypoxia-mediated miR-212-3p downregulation enhances progression of intrahepatic cholangiocarcinoma through upregulation of Rab1a.
Hou P, Kang Y, Luo J
Cancer biology & therapy 2018;19(11):984-993
Cancer biology & therapy 2018;19(11):984-993
The miR-199a-3p regulates the radioresistance of esophageal cancer cells via targeting the AK4 gene.
Zang C, Zhao F, Hua L, Pu Y
Cancer cell international 2018;18:186
Cancer cell international 2018;18:186
R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.
Ye J, Liu S, Shang Y, Chen H, Wang R
Cell cycle (Georgetown, Tex.) 2018;17(8):1014-1025
Cell cycle (Georgetown, Tex.) 2018;17(8):1014-1025
Tetrandrine enhances radiosensitivity through the CDC25C/CDK1/cyclin B1 pathway in nasopharyngeal carcinoma cells.
Wang J, Chang L, Lai X, Li X, Wang Z, Huang Z, Huang J, Zhang G
Cell cycle (Georgetown, Tex.) 2018;17(6):671-680
Cell cycle (Georgetown, Tex.) 2018;17(6):671-680
FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1α/CEACAM5 functional axis.
Li Q, Li Y, Li J, Ma Y, Dai W, Mo S, Xu Y, Li X, Cai S
International journal of biological sciences 2018;14(7):726-735
International journal of biological sciences 2018;14(7):726-735
Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression.
Sampaio NG, Kocan M, Schofield L, Pfleger KDG, Eriksson EM
PloS one 2018;13(8):e0202408
PloS one 2018;13(8):e0202408
NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cells.
Ma X, Wang B, Wang X, Luo Y, Fan W
PloS one 2018;13(4):e0192436
PloS one 2018;13(4):e0192436
Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2).
Dvorak KM, Pettee KM, Rubinic-Minotti K, Su R, Nestor-Kalinoski A, Eisenmann KM
PloS one 2018;13(3):e0195278
PloS one 2018;13(3):e0195278
Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.
Zhang HM, Liu P, Jiang C, Jin XQ, Liu RN, Li SQ, Zhao Y
PloS one 2018;13(2):e0193037
PloS one 2018;13(2):e0193037
Photothermal exposure of polydopamine-coated branched Au-Ag nanoparticles induces cell cycle arrest, apoptosis, and autophagy in human bladder cancer cells.
Zhao X, Qi T, Kong C, Hao M, Wang Y, Li J, Liu B, Gao Y, Jiang J
International journal of nanomedicine 2018;13:6413-6428
International journal of nanomedicine 2018;13:6413-6428
Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus.
Su WJ, Zhang T, Jiang CL, Wang W
Frontiers in cellular neuroscience 2018;12:412
Frontiers in cellular neuroscience 2018;12:412
Inhibition of Connexin 43 and Phosphorylated NR2B in Spinal Astrocytes Attenuates Bone Cancer Pain in Mice.
Yang H, Yan H, Li X, Liu J, Cao S, Huang B, Huang D, Wu L
Frontiers in cellular neuroscience 2018;12:129
Frontiers in cellular neuroscience 2018;12:129
Adipocyte ADRB3 Down-Regulated in Chinese Overweight Individuals Adipocyte ADRB3 in Overweight.
Cao WY, Liu Z, Guo F, Yu J, Li H, Yin X
Obesity facts 2018;11(6):524-533
Obesity facts 2018;11(6):524-533
High expression of Capn4 is associated with metastasis and poor prognosis in esophageal squamous cell carcinoma.
Wu X, Zhang H, Chen C, Gong L, Wang Y, Zhu X, Wang H, Yu Z
International journal of clinical and experimental pathology 2018;11(2):765-772
International journal of clinical and experimental pathology 2018;11(2):765-772
Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro.
Jiang T, Zhou ML, Fan J
OncoTargets and therapy 2018;11:7865-7872
OncoTargets and therapy 2018;11:7865-7872
PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation.
Lv JM, Chen L, Gao Y, Huang H, Pan XW, Liu X, Chen M, Qu FJ, Li L, Wang JK, Cui XG, Xu DF
OncoTargets and therapy 2018;11:5797-5809
OncoTargets and therapy 2018;11:5797-5809
CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway.
Jia Y, Xiao Z, Gongsun X, Xin Z, Shang B, Chen G, Wang Z, Jiang W
OncoTargets and therapy 2018;11:4221-4232
OncoTargets and therapy 2018;11:4221-4232
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Zuo Y, Wang J, Liao F, Yan X, Li J, Huang L, Liu F
Frontiers in molecular neuroscience 2018;11:401
Frontiers in molecular neuroscience 2018;11:401
Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo.
Ling Z, Guan H, You Z, Wang C, Hu L, Zhang L, Wang Y, Chen S, Xu B, Chen M
OncoTargets and therapy 2018;11:2735-2743
OncoTargets and therapy 2018;11:2735-2743
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
Chen T, Zhu H, Wang Y, Zhao P, Chen J, Sun J, Zhang X, Zhu G
American journal of translational research 2018;10(8):2555-2566
American journal of translational research 2018;10(8):2555-2566
MicroRNA-144-3p inhibits cell proliferation and induces cell apoptosis in prostate cancer by targeting CEP55.
Zheng H, Guo Z, Zheng X, Cheng W, Huang X
American journal of translational research 2018;10(8):2457-2468
American journal of translational research 2018;10(8):2457-2468
Aldosterone downregulates delayed rectifier potassium currents through an angiotensin type 1 receptor-dependent mechanism.
Lv Y, Wang Y, Zhu X, Zhang H
American journal of translational research 2018;10(5):1413-1421
American journal of translational research 2018;10(5):1413-1421
Advanced maternal age impairs spatial learning capacity in young adult mouse offspring.
Mao WJ, Wu ZY, Yang ZH, Xu YW, Wang SQ
American journal of translational research 2018;10(3):975-988
American journal of translational research 2018;10(3):975-988
LncRNA MALAT1 promotes relapse of breast cancer patients with postoperative fever.
Li Z, Xu L, Liu Y, Fu S, Tu J, Hu Y, Xiong Q
American journal of translational research 2018;10(10):3186-3197
American journal of translational research 2018;10(10):3186-3197
HJC0152, a novel STAT3 inhibitor with promising anti-tumor effect in gastric cancer.
Jiang X, Wu M, Xu Z, Wang H, Wang H, Yu X, Li Z, Teng L
Cancer management and research 2018;10:6857-6867
Cancer management and research 2018;10:6857-6867
DNA Methylation Profiling Reveals the Change of Inflammation-Associated ZC3H12D in Leukoaraiosis.
Huang WQ, Yi KH, Li Z, Wang H, Li ML, Cai LL, Lin HN, Lin Q, Tzeng CM
Frontiers in aging neuroscience 2018;10:143
Frontiers in aging neuroscience 2018;10:143
The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia.
Lai M, Yao H, Shah SZA, Wu W, Wang D, Zhao Y, Wang L, Zhou X, Zhao D, Yang L
Frontiers in aging neuroscience 2018;10:116
Frontiers in aging neuroscience 2018;10:116
Aberrant expression of stress-induced phosphoprotein 1 in colorectal cancer and its clinicopathologic significance.
Zhang Z, Ren H, Yang L, Zhang X, Liang W, Wu H, Huang L, Kang J, Xu J, Zhai E, Cai S, He Y
Human pathology 2018 Sep;79:135-143
Human pathology 2018 Sep;79:135-143
Electroacupuncture Alleviated Neuronal Apoptosis Following Ischemic Stroke in Rats via Midkine and ERK/JNK/p38 Signaling Pathway.
Xing Y, Yang SD, Wang MM, Dong F, Feng YS, Zhang F
Journal of molecular neuroscience : MN 2018 Sep;66(1):26-36
Journal of molecular neuroscience : MN 2018 Sep;66(1):26-36
Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway.
Yin J, Guo J, Zhang Q, Cui L, Zhang L, Zhang T, Zhao J, Li J, Middleton A, Carmichael PL, Peng S
Toxicology in vitro : an international journal published in association with BIBRA 2018 Sep;51:1-10
Toxicology in vitro : an international journal published in association with BIBRA 2018 Sep;51:1-10
Increased expression of CHOP and LC3B in newborn rats with bronchopulmonary dysplasia.
Li M, Pan B, Shi Y, Fu J, Xue X
International journal of molecular medicine 2018 Sep;42(3):1653-1665
International journal of molecular medicine 2018 Sep;42(3):1653-1665
Knockdown of NUPR1 inhibits the growth of U266 and RPMI8226 multiple myeloma cell lines via activating PTEN and caspase activation‑dependent apoptosis.
Zeng C, Li X, Li A, Yi B, Peng X, Huang X, Chen J
Oncology reports 2018 Sep;40(3):1487-1494
Oncology reports 2018 Sep;40(3):1487-1494
HOXA5 is a tumor suppressor gene that is decreased in gastric cancer.
Peng X, Zha L, Chen A, Wang Z
Oncology reports 2018 Sep;40(3):1317-1329
Oncology reports 2018 Sep;40(3):1317-1329
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, Li X, Xie C, Zhong C, Fu S
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
MicroRNA-222 Promotes Invasion and Metastasis of Papillary Thyroid Cancer Through Targeting Protein Phosphatase 2 Regulatory Subunit B Alpha Expression.
Huang Y, Yu S, Cao S, Yin Y, Hong S, Guan H, Li Y, Xiao H
Thyroid : official journal of the American Thyroid Association 2018 Sep;28(9):1162-1173
Thyroid : official journal of the American Thyroid Association 2018 Sep;28(9):1162-1173
Human CD31 on porcine cells suppress xenogeneic neutrophil-mediated cytotoxicity via the inhibition of NETosis.
Wang HT, Maeda A, Sakai R, Lo PC, Takakura C, Jiaravuthisan P, Mod Shabri A, Matsuura R, Kodama T, Hiwatashi S, Eguchi H, Okuyama H, Miyagawa S
Xenotransplantation 2018 Sep;25(5):e12396
Xenotransplantation 2018 Sep;25(5):e12396
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
Huang Y, Hu Z
Journal of cellular physiology 2018 Sep;233(9):7480-7496
Journal of cellular physiology 2018 Sep;233(9):7480-7496
Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity.
Liu H, Xie Y, Zhang Z, Mao P, Liu J, Ma W, Zhao Y
Neoplasia (New York, N.Y.) 2018 Sep;20(9):905-916
Neoplasia (New York, N.Y.) 2018 Sep;20(9):905-916
Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
Zhang XR, Wang SY, Sun W, Wei C
Molecular medicine reports 2018 Sep;18(3):3429-3436
Molecular medicine reports 2018 Sep;18(3):3429-3436
Decreased expression of TROAP suppresses cellular proliferation, migration and invasion in gastric cancer.
Jing K, Mao Q, Ma P
Molecular medicine reports 2018 Sep;18(3):3020-3026
Molecular medicine reports 2018 Sep;18(3):3020-3026
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Liang S, Jin J, Shen X, Jiang X, Li Y, He Q
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Protein kinase C-mediated impairment of glutamine outward transport and SN1 transporter distribution by ammonia in mouse cortical astrocytes.
Dąbrowska K, Albrecht J, Zielińska M
Neurochemistry international 2018 Sep;118:225-232
Neurochemistry international 2018 Sep;118:225-232
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
He J, Liu H, Zhong J, Guo Z, Wu J, Zhang H, Huang Z, Jiang L, Li H, Zhang Z, Liu L, Wu Y, Qi L, Sun X, Cheng C
Neurobiology of disease 2018 Sep;117:114-124
Neurobiology of disease 2018 Sep;117:114-124
MicroRNA-519d-3p inhibits cell proliferation and migration by targeting TROAP in colorectal cancer.
Ye X, Lv H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:879-886
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:879-886
Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats.
Long Y, Li S, Qin J, Xie L, Gan L, Jie F, Wu Y, Li Y, Du Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:781-788
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:781-788
Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells.
Wu D, Wang W, Chen W, Lian F, Lang L, Huang Y, Xu Y, Zhang N, Chen Y, Liu M, Nussinov R, Cheng F, Lu W, Huang J
Haematologica 2018 Sep;103(9):1472-1483
Haematologica 2018 Sep;103(9):1472-1483
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
Yi C, Wan X, Zhang Y, Fu F, Zhao C, Qin R, Wu H, Li Y, Huang Y
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
Effects of Guanfu total base on Bcl-2 and Bax expression and correlation with atrial fibrillation.
Li Y, Song B, Xu C
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 2018 Sep-Oct;59(5):274-278
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 2018 Sep-Oct;59(5):274-278
Adipose-specific expression of mouse Rbp7 gene and its developmental and metabolic changes.
Ahn J, Kim DH, Suh Y, Lee JW, Lee K
Gene 2018 Sep 5;670:38-45
Gene 2018 Sep 5;670:38-45
SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression.
Dong G, Wang B, An Y, Li J, Wang X, Jia J, Yang Q
Cell death & disease 2018 Sep 24;9(10):977
Cell death & disease 2018 Sep 24;9(10):977
Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway.
Qiu T, Pei P, Yao X, Jiang L, Wei S, Wang Z, Bai J, Yang G, Gao N, Yang L, Qi S, Yan R, Liu X, Sun X
Cell death & disease 2018 Sep 20;9(10):946
Cell death & disease 2018 Sep 20;9(10):946
mRNAs are sorted for export or degradation before passing through nuclear speckles.
Fan J, Kuai B, Wang K, Wang L, Wang Y, Wu X, Chi B, Li G, Cheng H
Nucleic acids research 2018 Sep 19;46(16):8404-8416
Nucleic acids research 2018 Sep 19;46(16):8404-8416
The selective Nlrp3 inflammasome inhibitor Mcc950 attenuates lung ischemia-reperfusion injury.
Xu KY, Wu CY, Tong S, Xiong P, Wang SH
Biochemical and biophysical research communications 2018 Sep 18;503(4):3031-3037
Biochemical and biophysical research communications 2018 Sep 18;503(4):3031-3037
UCH-L1 inhibition aggravates mossy fiber sprouting in the pentylenetetrazole kindling model.
Wen Y, Wu Q, Shi Q, Xie Y, Dan W, Chen Y, Ma L
Biochemical and biophysical research communications 2018 Sep 18;503(4):2312-2318
Biochemical and biophysical research communications 2018 Sep 18;503(4):2312-2318
CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer.
Zhong XY, Yuan XM, Xu YY, Yin M, Yan WW, Zou SW, Wei LM, Lu HJ, Wang YP, Lei QY
Cell reports 2018 Sep 18;24(12):3207-3223
Cell reports 2018 Sep 18;24(12):3207-3223
STING positively regulates human ORMDL3 expression through TBK1-IRF3-STAT6 complex mediation.
Cao Q, Juan CX, Zhang DQ, He J, Cao YZ, Pasha AB, Wang JY, Qi HX, Li S, Jin R, Zhou GP
Experimental cell research 2018 Sep 15;370(2):498-505
Experimental cell research 2018 Sep 15;370(2):498-505
The LncRNA MALAT1 regulates CD80 transcription via the NF-κB signaling pathway in the A549 cell line.
Juan C, Mao Y, Wang Q, Cao Q, Chen Y, Zhou G
Biochemical and biophysical research communications 2018 Sep 10;503(3):1674-1681
Biochemical and biophysical research communications 2018 Sep 10;503(3):1674-1681
Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-κB signaling pathways.
Jouda JB, Mfotie Njoya E, Mbazoa CD, Zhou Z, Meli Lannang A, Wandji J, Shiono Y, Wang F
Bioorganic chemistry 2018 Oct;80:216-222
Bioorganic chemistry 2018 Oct;80:216-222
Knockdown of ribosomal protein S15A inhibits proliferation of breast cancer cells through induction of apoptosis in vitro.
Feng W, Liang C, Wang C, Yu X, Li Q, Yang H
Cytotechnology 2018 Oct;70(5):1315-1323
Cytotechnology 2018 Oct;70(5):1315-1323
2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside potentiates self-renewal of human dental pulp stem cells via the AMPK/ERK/SIRT1 axis.
Lin CY, Chin YT, Kuo PJ, Lee HW, Huang HM, Lin HY, Weng IT, Hsiung CN, Chan YH, Lee SY
International endodontic journal 2018 Oct;51(10):1159-1170
International endodontic journal 2018 Oct;51(10):1159-1170
Dual-functionality of RASSF1A overexpression in A375 cells is mediated by activation of IL-6/STAT3 regulatory loop.
Yi M, Wang W, Chen S, Peng Y, Li J, Cai J, Zhou Y, Peng Q, Ban Y, Zeng Z, Li X, Xiong W, Li G, Xiang B
Molecular biology reports 2018 Oct;45(5):1277-1287
Molecular biology reports 2018 Oct;45(5):1277-1287
Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer.
Fan L, Huang C, Li J, Gao T, Lin Z, Yao T
International journal of molecular medicine 2018 Oct;42(4):2247-2259
International journal of molecular medicine 2018 Oct;42(4):2247-2259
PSMB4 overexpression enhances the cell growth and viability of breast cancer cells leading to a poor prognosis.
Wang H, He Z, Xia L, Zhang W, Xu L, Yue X, Ru X, Xu Y
Oncology reports 2018 Oct;40(4):2343-2352
Oncology reports 2018 Oct;40(4):2343-2352
MicroRNA-409-3p suppresses cell proliferation and cell cycle progression by targeting cyclin D2 in papillary thyroid carcinoma.
Zhao Z, Yang F, Liu Y, Fu K, Jing S
Oncology letters 2018 Oct;16(4):5237-5242
Oncology letters 2018 Oct;16(4):5237-5242
Eugenol protects the transplanted heart against ischemia/reperfusion injury in rats by inhibiting the inflammatory response and apoptosis.
Feng W, Jin L, Xie Q, Huang L, Jiang Z, Ji Y, Li C, Yang L, Wang D
Experimental and therapeutic medicine 2018 Oct;16(4):3464-3470
Experimental and therapeutic medicine 2018 Oct;16(4):3464-3470
Long non-coding RNA FTH1P3 regulated metastasis and invasion of esophageal squamous cell carcinoma through SP1/NF-kB pathway.
Yang L, Sun K, Chu J, Qu Y, Zhao X, Yin H, Ming L, Wan J, He F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1570-1577
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1570-1577
miR-497 may enhance the sensitivity of non-small cell lung cancer cells to gefitinib through targeting the insulin-like growth factor-1 receptor.
Ma W, Feng W, Tan J, Xu A, Hu Y, Ning L, Kang Y, Wang L, Zhao Z
Journal of thoracic disease 2018 Oct;10(10):5889-5897
Journal of thoracic disease 2018 Oct;10(10):5889-5897
A Pre-Clinical Large Animal Model of Sustained Liver Injury and Regeneration Stimulus.
Inomata K, Tajima K, Yagi H, Higashi H, Shimoda H, Matsubara K, Hibi T, Abe Y, Tsujikawa H, Kitago M, Shinoda M, Obara H, Itano O, Soto-Gutierrez A, Kitagawa Y
Scientific reports 2018 Oct 9;8(1):14987
Scientific reports 2018 Oct 9;8(1):14987
Proteomic profile in the mussel Perna viridis after short-term exposure to the brown tide alga Aureococcus anophagefferens.
Zheng JW, Liu SL, Lu SH, Li HY, Liu JS, Yang WD
Ecotoxicology and environmental safety 2018 Oct 30;162:365-375
Ecotoxicology and environmental safety 2018 Oct 30;162:365-375
Long non-coding RNA OGFRP1 regulates LYPD3 expression by sponging miR-124-3p and promotes non-small cell lung cancer progression.
Tang LX, Chen GH, Li H, He P, Zhang Y, Xu XW
Biochemical and biophysical research communications 2018 Oct 28;505(2):578-585
Biochemical and biophysical research communications 2018 Oct 28;505(2):578-585
Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury.
Wang Y, Chen M
Biochemical and biophysical research communications 2018 Oct 20;505(1):151-156
Biochemical and biophysical research communications 2018 Oct 20;505(1):151-156
A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.
Hewit K, Sandilands E, Martinez RS, James D, Leung HY, Bryant DM, Shanks E, Markert EK
Cell death & disease 2018 Oct 19;9(11):1069
Cell death & disease 2018 Oct 19;9(11):1069
Increased expression of heat shock factor 1 (HSF1) is associated with poor survival in gastric cancer patients.
Dai W, Ye J, Zhang Z, Yang L, Ren H, Wu H, Chen J, Ma J, Zhai E, Cai S, He Y
Diagnostic pathology 2018 Oct 17;13(1):80
Diagnostic pathology 2018 Oct 17;13(1):80
Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α.
Yan B, Jiang Z, Cheng L, Chen K, Zhou C, Sun L, Qian W, Li J, Cao J, Xu Q, Ma Q, Lei J
Experimental cell research 2018 Oct 1;371(1):63-71
Experimental cell research 2018 Oct 1;371(1):63-71
1α,25-dihydroxyvitamin D3 promotes osseointegration of titanium implant via downregulating AGEs/RAGE pathway in T2DM.
Jia T, Wang YN, Zhang D, Xu X
Endocrine connections 2018 Nov;7(11):1186-1195
Endocrine connections 2018 Nov;7(11):1186-1195
Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high-fat diet-fed mice.
Yin J, Li Y, Han H, Chen S, Gao J, Liu G, Wu X, Deng J, Yu Q, Huang X, Fang R, Li T, Reiter RJ, Zhang D, Zhu C, Zhu G, Ren W, Yin Y
Journal of pineal research 2018 Nov;65(4):e12524
Journal of pineal research 2018 Nov;65(4):e12524
Identification of a Novel Function of Resveratrol and Genistein as a Regulator of β(2) -Adrenergic Receptor Expression in Skeletal Muscle Cells and Characterization of Promoter Elements Required for Promoter Activation.
Chikazawa M, Sato R
Molecular nutrition & food research 2018 Nov;62(22):e1800530
Molecular nutrition & food research 2018 Nov;62(22):e1800530
β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors.
You C, Zhang S, Sun Y, Zhang S, Tang G, Tang F, Liu X, Xiao Y, Zhang J, Gong Y, Xie C
International journal of oncology 2018 Nov;53(5):2258-2268
International journal of oncology 2018 Nov;53(5):2258-2268
mRNA m(6)A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.
Wang X, Sun B, Jiang Q, Wu R, Cai M, Yao Y, Liu Q, Shi H, Feng J, Wang Y
International journal of obesity (2005) 2018 Nov;42(11):1912-1924
International journal of obesity (2005) 2018 Nov;42(11):1912-1924
Overexpression of Epsin 3 enhances migration and invasion of glioma cells by inducing epithelial‑mesenchymal transition.
Wang Y, Song W, Kan P, Huang C, Ma Z, Wu Q, Yao X, Zhang B
Oncology reports 2018 Nov;40(5):3049-3059
Oncology reports 2018 Nov;40(5):3049-3059
Possible Involvement of PTEN Signaling Pathway in the Anti-apoptotic Effect of Electroacupuncture Following Ischemic Stroke in Rats.
Xing Y, Wang MM, Feng YS, Dong F, Zhang F
Cellular and molecular neurobiology 2018 Nov;38(8):1453-1463
Cellular and molecular neurobiology 2018 Nov;38(8):1453-1463
Role of dihydroartemisinin in regulating prostaglandin E(2) synthesis cascade and inflammation in endothelial cells.
Yin J, Xia W, Zhang Y, Ding G, Chen L, Yang G, Huang S, Jia Z, Zhang A
Heart and vessels 2018 Nov;33(11):1411-1422
Heart and vessels 2018 Nov;33(11):1411-1422
Protocatechuic acid inhibits the growth of ovarian cancer cells by inducing apoptosis and autophagy.
Xie Z, Guo Z, Wang Y, Lei J, Yu J
Phytotherapy research : PTR 2018 Nov;32(11):2256-2263
Phytotherapy research : PTR 2018 Nov;32(11):2256-2263
MiR-1301-3p inhibits human breast cancer cell proliferation by regulating cell cycle progression and apoptosis through directly targeting ICT1.
Peng X, Yan B, Shen Y
Breast cancer (Tokyo, Japan) 2018 Nov;25(6):742-752
Breast cancer (Tokyo, Japan) 2018 Nov;25(6):742-752
Upregulation of HSP60 expression in the postnatal rat cochlea and rats with drug-induced hearing loss.
Tian K, Song Y, Zhou K, Yue B, Qiu Y, Sun F, Wang R, Zha D, Qiu J
Cell stress & chaperones 2018 Nov;23(6):1311-1317
Cell stress & chaperones 2018 Nov;23(6):1311-1317
CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4‑activated MEK/ERK and PI3K/AKT pathways.
Tian Y, Yin H, Deng X, Tang B, Ren X, Jiang T
Molecular medicine reports 2018 Nov;18(5):4374-4380
Molecular medicine reports 2018 Nov;18(5):4374-4380
Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes.
Wang Z, Ren J, Liu Q, Li J, Wu X, Wang W, Wu J, Wang G, Li J
Thrombosis research 2018 Nov;171:45-54
Thrombosis research 2018 Nov;171:45-54
Downregulation of 5-hydroxytryptamine receptor 3A expression exerts an anticancer activity against cell growth in colorectal carcinoma cells in vitro.
Tang J, Wang Z, Liu J, Zhou C, Chen J
Oncology letters 2018 Nov;16(5):6100-6108
Oncology letters 2018 Nov;16(5):6100-6108
Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition.
Song R, Hou G, Yang J, Yuan J, Wang C, Chai T, Liu Z
Oncology letters 2018 Nov;16(5):5739-5744
Oncology letters 2018 Nov;16(5):5739-5744
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
Yue X, Li M, Chen D, Xu Z, Sun S
Experimental and therapeutic medicine 2018 Nov;16(5):3921-3928
Experimental and therapeutic medicine 2018 Nov;16(5):3921-3928
Solute Carrier Organic Anion Transporter Family Member 3A1 Is a Bile Acid Efflux Transporter in Cholestasis.
Pan Q, Zhang X, Zhang L, Cheng Y, Zhao N, Li F, Zhou X, Chen S, Li J, Xu S, Huang D, Chen Y, Li L, Wang H, Chen W, Cai SY, Boyer JL, Chai J
Gastroenterology 2018 Nov;155(5):1578-1592.e16
Gastroenterology 2018 Nov;155(5):1578-1592.e16
Novel Podophyllotoxin Derivatives as Potential Tubulin Inhibitors: Design, Synthesis, and Antiproliferative Activity Evaluation.
Han HW, Lin HY, He DL, Ren Y, Sun WX, Liang L, Du MH, Li DC, Chu YC, Yang MK, Wang XM, Yang YH
Chemistry & biodiversity 2018 Nov;15(11):e1800289
Chemistry & biodiversity 2018 Nov;15(11):e1800289
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
MiR-133a acts as an anti-oncogene in Hepatocellular carcinoma by inhibiting FOSL2 through TGF-β/Smad3 signaling pathway.
Sun L, Guo Z, Sun J, Li J, Dong Z, Zhang Y, Chen J, Kan Q, Yu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:168-176
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:168-176
Knockdown of LncRNA MALAT1 contributes to cell apoptosis via regulating NF-κB/CD80 axis in neonatal respiratory distress syndrome.
Juan C, Wang Q, Mao Y, Cao Q, Li S, Qiao C, Zhang D, Zhou G
The international journal of biochemistry & cell biology 2018 Nov;104:138-148
The international journal of biochemistry & cell biology 2018 Nov;104:138-148
Screening of differentially expressed proteins from syncytiotrophoblast for severe early-onset preeclampsia in women with gestational diabetes mellitus using tandem mass tag quantitative proteomics.
Sun X, Qu T, He X, Yang X, Guo N, Mao Y, Xu X, Sun X, Zhang X, Wang W
BMC pregnancy and childbirth 2018 Nov 7;18(1):437
BMC pregnancy and childbirth 2018 Nov 7;18(1):437
On the use of abiotic sialic acids to attenuate cell inflammation.
Xue Z, Zhao H, Zhu R, Chen C, Cao H, Han J, Han S
Scientific reports 2018 Nov 23;8(1):17320
Scientific reports 2018 Nov 23;8(1):17320
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Dong W, Yang B, Wang Y, Yuan J, Fan Y, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
The pro-metastasis effect of circANKS1B in breast cancer.
Zeng K, He B, Yang BB, Xu T, Chen X, Xu M, Liu X, Sun H, Pan Y, Wang S
Molecular cancer 2018 Nov 19;17(1):160
Molecular cancer 2018 Nov 19;17(1):160
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
Li M, Lu Y, Xu Y, Wang J, Zhang C, Du Y, Wang L, Li L, Wang B, Shen J, Tang J, Song B
Gene 2018 Nov 15;676:101-109
Gene 2018 Nov 15;676:101-109
Saponins from Boussingaultia gracilis prevent obesity and related metabolic impairments in diet-induced obese mice.
Liu L, Wang N, Ma Y, Liu Y, Wen D
Food & function 2018 Nov 14;9(11):5660-5673
Food & function 2018 Nov 14;9(11):5660-5673
Retraction: Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
Zhang Y, Xiao F, Zhong C, Zeng M, Zou L
Metallomics : integrated biometal science 2018 Nov 14;10(11):1701
Metallomics : integrated biometal science 2018 Nov 14;10(11):1701
LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.
Feng M, Xiong G, Cao Z, Yang G, Zheng S, Qiu J, You L, Zheng L, Zhang T, Zhao Y
Journal of experimental & clinical cancer research : CR 2018 Nov 12;37(1):274
Journal of experimental & clinical cancer research : CR 2018 Nov 12;37(1):274
Downregulation of LINC00894-002 Contributes to Tamoxifen Resistance by Enhancing the TGF-β Signaling Pathway.
Zhang X, Wang M, Sun H, Zhu T, Wang X
Biochemistry. Biokhimiia 2018 May;83(5):603-611
Biochemistry. Biokhimiia 2018 May;83(5):603-611
Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.
Chen C, Lei J, Zheng Q, Tan S, Ding K, Yu C
FEBS open bio 2018 May;8(5):764-773
FEBS open bio 2018 May;8(5):764-773
Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells.
Lai X, Su W, Zhao H, Yang S, Zeng T, Wu W, Wang D
FEBS open bio 2018 May;8(5):743-750
FEBS open bio 2018 May;8(5):743-750
EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma.
Zeng R, Liu Y, Jiang ZJ, Huang JP, Wang Y, Li XF, Xiong WB, Wu XC, Zhang JR, Wang QE, Zheng YF
International journal of oncology 2018 May;52(5):1443-1454
International journal of oncology 2018 May;52(5):1443-1454
The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion.
Luo B, Chen K, Feng Q, Xiao W, Ma D, Yang H, Zhang C
International journal of molecular medicine 2018 May;41(5):2640-2650
International journal of molecular medicine 2018 May;41(5):2640-2650
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
Shi J, Li F, Yao X, Mou T, Xu Z, Han Z, Chen S, Li W, Yu J, Qi X, Liu H, Li G
Oncogene 2018 May;37(22):3022-3038
Oncogene 2018 May;37(22):3022-3038
INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway.
Chen Y, Sun Z, Qi M, Wang X, Zhang W, Chen C, Liu J, Zhao W
Journal of cellular and molecular medicine 2018 May;22(5):2935-2943
Journal of cellular and molecular medicine 2018 May;22(5):2935-2943
Downregulation of microRNA-142-3p and its tumor suppressor role in gastric cancer.
Wang Y, Cao Z, Wang L, Liu S, Cai J
Oncology letters 2018 May;15(5):8172-8180
Oncology letters 2018 May;15(5):8172-8180
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Li T, Zhang L, Huo X
Oncology letters 2018 May;15(5):7118-7122
Oncology letters 2018 May;15(5):7118-7122
Targeted silencing of the ADP-ribosyltransferase 3 gene inhibits the migration ability of melanoma cells.
He J, Li Y, Wang Y, Zhang H, Ge S, Fan X
Oncology letters 2018 May;15(5):7053-7059
Oncology letters 2018 May;15(5):7053-7059
Downregulation of TACC3 inhibits tumor growth and migration in osteosarcoma cells through regulation of the NF-κB signaling pathway.
Zhao C, He X, Li H, Zhou J, Han X, Wang D, Tian G, Sui F
Oncology letters 2018 May;15(5):6881-6886
Oncology letters 2018 May;15(5):6881-6886
BTB/POZ domain-containing protein 7 is inversely associated with fibronectin expression in salivary adenoid cystic carcinoma.
Liu Y, Song J, Zhang J, Yang L, Liu Z, Wang X
Oral surgery, oral medicine, oral pathology and oral radiology 2018 May;125(5):468-477
Oral surgery, oral medicine, oral pathology and oral radiology 2018 May;125(5):468-477
After Treatment with Methylene Blue is Effective against Delayed Encephalopathy after Acute Carbon Monoxide Poisoning.
Zhao N, Liang P, Zhuo X, Su C, Zong X, Guo B, Han D, Yan X, Hu S, Zhang Q, Tie X
Basic & clinical pharmacology & toxicology 2018 May;122(5):470-480
Basic & clinical pharmacology & toxicology 2018 May;122(5):470-480
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Liang M, Wang Z, Li H, Cai L, Pan J, He H, Wu Q, Tang Y, Ma J, Yang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328
BACH1 promotes the progression of human colorectal cancer through BACH1/CXCR4 pathway.
Zhu GD, Liu F, OuYang S, Zhou R, Jiang FN, Zhang B, Liao WJ
Biochemical and biophysical research communications 2018 May 5;499(2):120-127
Biochemical and biophysical research communications 2018 May 5;499(2):120-127
The NK1 receptor antagonist NKP608 inhibits proliferation of human colorectal cancer cells via Wnt signaling pathway.
Niu XL, Hou JF, Li JX
Biological research 2018 May 30;51(1):14
Biological research 2018 May 30;51(1):14
Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity.
Liu K, Li D, Hao G, McCaffary D, Neely O, Woodward L, Ioannides D, Lu CJ, Brescia M, Zaccolo M, Tandri H, Ajijola OA, Ardell JL, Shivkumar K, Paterson DJ
JCI insight 2018 May 3;3(9)
JCI insight 2018 May 3;3(9)
Targeting mTORC1/2 Complexes Inhibit Tumorigenesis and Enhance Sensitivity to 5-Flourouracil (5-FU) in Hepatocellular Carcinoma: A Preclinical Study of mTORC1/2-Targeted Therapy in Hepatocellular Carcinoma (HCC).
Zhang Y, Jia QA, Kadel D, Zhang XF, Zhang QB
Medical science monitor : international medical journal of experimental and clinical research 2018 May 3;24:2735-2743
Medical science monitor : international medical journal of experimental and clinical research 2018 May 3;24:2735-2743
Neuroglobin mediates neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in rats through preserving the activity of Na(+)/K(+) ATPases.
Wen H, Liu L, Zhan L, Liang D, Li L, Liu D, Sun W, Xu E
Cell death & disease 2018 May 25;9(6):635
Cell death & disease 2018 May 25;9(6):635
6-Formylindolo(3,2-b)carbazole induced aryl hydrocarbon receptor activation prevents intestinal barrier dysfunction through regulation of claudin-2 expression.
Ma Y, Wang Q, Yu K, Fan X, Xiao W, Cai Y, Xu P, Yu M, Yang H
Chemico-biological interactions 2018 May 25;288:83-90
Chemico-biological interactions 2018 May 25;288:83-90
MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma.
Wu T, Lin Y, Xie Z
Biological research 2018 May 24;51(1):13
Biological research 2018 May 24;51(1):13
HSF4 transcriptional regulates HMOX-1 expression in HLECs.
Liao S, Qu Z, Li L, Zhou B, Gao M, Huang M, Li D
Gene 2018 May 20;655:30-34
Gene 2018 May 20;655:30-34
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
Wu DD, Gao YR, Li T, Wang DY, Lu D, Liu SY, Hong Y, Ning HB, Liu JP, Shang J, Shi JF, Wei JS, Ji XY
BMC cancer 2018 May 2;18(1):499
BMC cancer 2018 May 2;18(1):499
Long noncoding RNA TUG1 facilitates osteogenic differentiation of periodontal ligament stem cells via interacting with Lin28A.
He Q, Yang S, Gu X, Li M, Wang C, Wei F
Cell death & disease 2018 May 1;9(5):455
Cell death & disease 2018 May 1;9(5):455
Interfering RNA against PKC-α inhibits TNF-α-induced IP(3)R1 expression and improves glomerular filtration rate in rats with fulminant hepatic failure.
Wang DL, Dai WY, Wang W, Wen Y, Zhou Y, Zhao YT, Wu J, Liu P
American journal of physiology. Renal physiology 2018 May 1;314(5):F942-F955
American journal of physiology. Renal physiology 2018 May 1;314(5):F942-F955
Reduced-gliotoxin induces ROS-mediated anoikis in human colorectal cancer cells.
Chen J, Lou Q, He L, Wen C, Lin M, Zhu Z, Wang F, Huang L, Lan W, Iwamoto A, Yang X, Liu H
International journal of oncology 2018 Mar;52(3):1023-1032
International journal of oncology 2018 Mar;52(3):1023-1032
Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma.
Chang J, Zhong R, Tian J, Li J, Zhai K, Ke J, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Zhu Y, Gong Y, Yang Y, Zou D, Peng X, Zhang Z, Zhang X, Huang K, Wu T, Wu C, Miao X, Lin D
Nature genetics 2018 Mar;50(3):338-343
Nature genetics 2018 Mar;50(3):338-343
SOX4 contributes to TGF-β-induced epithelial-mesenchymal transition and stem cell characteristics of gastric cancer cells.
Peng X, Liu G, Peng H, Chen A, Zha L, Wang Z
Genes & diseases 2018 Mar;5(1):49-61
Genes & diseases 2018 Mar;5(1):49-61
Exogenous hydrogen sulfide protects human umbilical vein endothelial cells against high glucose‑induced injury by inhibiting the necroptosis pathway.
Lin J, Chen M, Liu D, Guo R, Lin K, Deng H, Zhi X, Zhang W, Feng J, Wu W
International journal of molecular medicine 2018 Mar;41(3):1477-1486
International journal of molecular medicine 2018 Mar;41(3):1477-1486
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
Zhao P, Chang RY, Liu N, Wang J, Zhou R, Qi X, Liu Y, Ma L, Niu Y, Sun T, Li YX, He YP, Yu JQ
Cellular and molecular neurobiology 2018 Mar;38(2):529-540
Cellular and molecular neurobiology 2018 Mar;38(2):529-540
UBAP2L silencing inhibits cell proliferation and G2/M phase transition in breast cancer.
He J, Chen Y, Cai L, Li Z, Guo X
Breast cancer (Tokyo, Japan) 2018 Mar;25(2):224-232
Breast cancer (Tokyo, Japan) 2018 Mar;25(2):224-232
In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.
Zhou H, Liu J, Zhou C, Gao N, Rao Z, Li H, Hu X, Li C, Yao X, Shen X, Sun Y, Wei Y, Liu F, Ying W, Zhang J, Tang C, Zhang X, Xu H, Shi L, Cheng L, Huang P, Yang H
Nature neuroscience 2018 Mar;21(3):440-446
Nature neuroscience 2018 Mar;21(3):440-446
Effects of intrathecal bupivacaine on the NR2B/CaMKIIα/CREB signaling pathway in the rat lumbar spinal cord.
Zhao L, Zhang Y, Yang F, Zhu D, Li N, Zhao L, Li N, Yu J, Ma H
Molecular medicine reports 2018 Mar;17(3):4508-4514
Molecular medicine reports 2018 Mar;17(3):4508-4514
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Yu L, Wang S, Lin X, Lu Y, Gu P
Molecular medicine reports 2018 Mar;17(3):3972-3978
Molecular medicine reports 2018 Mar;17(3):3972-3978
Prognostic significance of sodium-potassium ATPase regulator, FXYD3, in human hepatocellular carcinoma.
Wang LJ, Li QJ, Le Y, Ouyang HY, He MK, Yu ZS, Zhang YF, Shi M
Oncology letters 2018 Mar;15(3):3024-3030
Oncology letters 2018 Mar;15(3):3024-3030
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Wang Z, Cui R, Wang K
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Liu S, Liu B
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis.
Cao R, Jin W, Shan Y, Wang J, Liu G, Kuang S, Sun C
Marine drugs 2018 Mar 8;16(3)
Marine drugs 2018 Mar 8;16(3)
Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome.
Han L, Xin X, Wang H, Li J, Hao Y, Wang M, Zheng C, Shen C
Scientific reports 2018 Mar 22;8(1):5074
Scientific reports 2018 Mar 22;8(1):5074
[Expression of DKKL1 in spermatozoa of men with asthenospermia].
Yan QX, Ma Y, Chen RQ, Zhou XQ, Qiao J, Xian YJ, Feng L, Chen CR
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 Mar 20;38(3):324-328
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 Mar 20;38(3):324-328
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Guo J, Cai H, Liu X, Zheng J, Liu Y, Gong W, Chen J, Xi Z, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer.
Fang Z, Cao B, Liao JM, Deng J, Plummer KD, Liao P, Liu T, Zhang W, Zhang K, Li L, Margolin D, Zeng SX, Xiong J, Lu H
eLife 2018 Mar 16;7
eLife 2018 Mar 16;7
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Chen S, Deng G, Li K, Zheng H, Wang G, Yu B, Zhang K
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
SOX8 regulates cancer stem-like properties and cisplatin-induced EMT in tongue squamous cell carcinoma by acting on the Wnt/β-catenin pathway.
Xie SL, Fan S, Zhang SY, Chen WX, Li QX, Pan GK, Zhang HQ, Wang WW, Weng B, Zhang Z, Li JS, Lin ZY
International journal of cancer 2018 Mar 15;142(6):1252-1265
International journal of cancer 2018 Mar 15;142(6):1252-1265
Roles of high-mobility group box 1 and thrombin in murine pulmonary fibrosis and the therapeutic potential of thrombomodulin.
Kida T, Seno T, Nagahara H, Inoue T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Wada M, Kohno M, Kawahito Y
American journal of physiology. Lung cellular and molecular physiology 2018 Mar 1;314(3):L473-L483
American journal of physiology. Lung cellular and molecular physiology 2018 Mar 1;314(3):L473-L483
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Qiao Y, Xu L, Tao X, Yin L, Qi Y, Xu Y, Han X, Tang Z, Ma X, Liu K, Peng J
Toxicology letters 2018 Mar 1;284:37-45
Toxicology letters 2018 Mar 1;284:37-45
Pyrethroid Insecticide Cypermethrin Modulates Gonadotropin Synthesis via Calcium Homeostasis and ERK1/2 Signaling in LβT2 Mouse Pituitary Cells.
Li F, Ma H, Liu J
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):43-52
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):43-52
Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance-Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator-Activated Receptor α Activation.
Wang L, Ma L, Lin Y, Liu X, Xiao L, Zhang Y, Xu Y, Zhou H, Pan G
Molecular pharmacology 2018 Jun;93(6):563-574
Molecular pharmacology 2018 Jun;93(6):563-574
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
B7-H6 expression is induced by lipopolysaccharide and facilitates cancer invasion and metastasis in human gliomas.
Che F, Xie X, Wang L, Su Q, Jia F, Ye Y, Zang L, Wang J, Li H, Quan Y, You C, Yin J, Wang Z, Li G, Du Y, Wang L
International immunopharmacology 2018 Jun;59:318-327
International immunopharmacology 2018 Jun;59:318-327
Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling.
Ren J, Jian F, Jiang H, Sun Y, Pan S, Gu C, Chen X, Wang W, Ning G, Bian L, Sun Q
International journal of oncology 2018 Jun;52(6):1934-1946
International journal of oncology 2018 Jun;52(6):1934-1946
NIK‑ and IKKβ‑binding protein contributes to gastric cancer chemoresistance by promoting epithelial‑mesenchymal transition through the NF‑κB signaling pathway.
Fu ZH, Liu SQ, Qin MB, Huang JA, Xu CY, Wu WH, Zhu LY, Qin N, Lai MY
Oncology reports 2018 Jun;39(6):2721-2730
Oncology reports 2018 Jun;39(6):2721-2730
Inhibition of HSP90α protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression.
Wang Z, Guo LM, Wang Y, Zhou HK, Wang SC, Chen D, Huang JF, Xiong K
Journal of cellular physiology 2018 Jun;233(6):4864-4884
Journal of cellular physiology 2018 Jun;233(6):4864-4884
Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells.
Xu C, Zhang W, Liu S, Wu W, Qin M, Huang J
Oncology letters 2018 Jun;15(6):9719-9724
Oncology letters 2018 Jun;15(6):9719-9724
Association of HMGB1, BRCA1 and P62 expression in ovarian cancer and chemotherapy sensitivity.
Li S, Wei Y
Oncology letters 2018 Jun;15(6):9572-9576
Oncology letters 2018 Jun;15(6):9572-9576
Tumor necrosis factor receptor 2 may promote the proliferation and drug resistance of Kapras299 and L428 lymphoma cells via the AKT and WNT/β-catenin signaling pathways.
Liang Y, Wang Y, Xiao M, Hao Y, Zhang Y, Li S
Oncology letters 2018 Jun;15(6):8847-8852
Oncology letters 2018 Jun;15(6):8847-8852
Knockdown of serine/threonine protein phosphatase 5 enhances gemcitabine sensitivity by promoting apoptosis in pancreatic cancer cells in vitro.
Zhu J, Ji Y, Yu Y, Jin Y, Zhang X, Zhou J, Chen Y
Oncology letters 2018 Jun;15(6):8761-8769
Oncology letters 2018 Jun;15(6):8761-8769
Knockdown of stromal interaction molecule 1 inhibits proliferation of colorectal cancer cells by inducing apoptosis.
Yang D, Dai X, Li K, Xie Y, Zhao J, Dong M, Yu H, Kong Z
Oncology letters 2018 Jun;15(6):8231-8236
Oncology letters 2018 Jun;15(6):8231-8236
Small interfering RNA-mediated silencing of G-protein-coupled receptor 137 inhibits growth of osteosarcoma cells.
Li H, Fu X, Gao Y, Li X, Shen Y, Wang W
Journal of bone oncology 2018 Jun;11:17-22
Journal of bone oncology 2018 Jun;11:17-22
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Zhang JR, Lu QB, Feng WB, Wang HP, Tang ZH, Cheng H, Du Q, Wang YB, Li KX, Sun HJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Zhu X, Li Z, Li T, Long F, Lv Y, Liu L, Liu X, Zhan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Baicalein inhibits growth of Epstein-Barr virus-positive nasopharyngeal carcinoma by repressing the activity of EBNA1 Q-promoter.
Zhang Y, Wang H, Liu Y, Wang C, Wang J, Long C, Guo W, Sun X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:1003-1014
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:1003-1014
HuR regulates telomerase activity through TERC methylation.
Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Gorospe M, Ju Z, Wang W
Nature communications 2018 Jun 7;9(1):2213
Nature communications 2018 Jun 7;9(1):2213
STAT3 activation by IL-6 from adipose-derived stem cells promotes endometrial carcinoma proliferation and metastasis.
Chu Y, Wang Y, Peng W, Xu L, Liu M, Li J, Hu X, Li Y, Zuo J, Ye Y
Biochemical and biophysical research communications 2018 Jun 7;500(3):626-631
Biochemical and biophysical research communications 2018 Jun 7;500(3):626-631
Chemotherapy-Induced Long Non-coding RNA 1 Promotes Metastasis and Chemo-Resistance of TSCC via the Wnt/β-Catenin Signaling Pathway.
Lin Z, Sun L, Xie S, Zhang S, Fan S, Li Q, Chen W, Pan G, Wang W, Weng B, Zhang Z, Liu B, Li J
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Jun 6;26(6):1494-1508
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Jun 6;26(6):1494-1508
MiR-199a-3p affects the multi-chemoresistance of osteosarcoma through targeting AK4.
Lei W, Yan C, Ya J, Yong D, Yujun B, Kai L
BMC cancer 2018 Jun 4;18(1):631
BMC cancer 2018 Jun 4;18(1):631
Host Factor SPCS1 Regulates the Replication of Japanese Encephalitis Virus through Interactions with Transmembrane Domains of NS2B.
Ma L, Li F, Zhang JW, Li W, Zhao DM, Wang H, Hua RH, Bu ZG
Journal of virology 2018 Jun 15;92(12)
Journal of virology 2018 Jun 15;92(12)
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Xu C, Zhang H, Gu W, Wu H, Chen Y, Zhou W, Sun B, Shen X, Zhang Z, Wang Y, Liu Y, Yuan W
Scientific reports 2018 Jun 15;8(1):9225
Scientific reports 2018 Jun 15;8(1):9225
α-Viniferin activates autophagic apoptosis and cell death by reducing glucocorticoid receptor expression in castration-resistant prostate cancer cells.
Cheng K, Liu X, Chen L, Lv JM, Qu FJ, Pan XW, Li L, Cui XG, Gao Y, Xu DF
Medical oncology (Northwood, London, England) 2018 Jun 15;35(7):105
Medical oncology (Northwood, London, England) 2018 Jun 15;35(7):105
Air pollution is associated with the development of atherosclerosis via the cooperation of CD36 and NLRP3 inflammasome in ApoE(-/-) mice.
Du X, Jiang S, Zeng X, Zhang J, Pan K, Zhou J, Xie Y, Kan H, Song W, Sun Q, Zhao J
Toxicology letters 2018 Jun 15;290:123-132
Toxicology letters 2018 Jun 15;290:123-132
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Wang S, Xu M, Li X, Su X, Xiao X, Keating A, Zhao RC
Journal of hematology & oncology 2018 Jun 14;11(1):82
Journal of hematology & oncology 2018 Jun 14;11(1):82
Chronic low-dose exposure of nonylphenol alters energy homeostasis in the reproductive system of female rats.
Di QN, Cao WX, Xu R, Lu L, Xu Q, Wang XB
Toxicology and applied pharmacology 2018 Jun 1;348:67-75
Toxicology and applied pharmacology 2018 Jun 1;348:67-75
Robust, pleiotropic drug resistance 5 (Pdr5)-mediated multidrug resistance is vigorously maintained in Saccharomyces cerevisiae cells during glucose and nitrogen limitation.
Rahman H, Carneglia J, Lausten M, Robertello M, Choy J, Golin J
FEMS yeast research 2018 Jun 1;18(4)
FEMS yeast research 2018 Jun 1;18(4)
Rho-kinase inhibitor Y-27632 downregulates LPS-induced IL-6 and IL-8 production via blocking p38 MAPK and NF-κB pathways in human gingival fibroblasts.
Kang W, Shang L, Wang T, Liu H, Ge S
Journal of periodontology 2018 Jul;89(7):883-893
Journal of periodontology 2018 Jul;89(7):883-893
Harmine, a small molecule derived from natural sources, inhibits enterovirus 71 replication by targeting NF-κB pathway.
Chen D, Tian X, Zou X, Xu S, Wang H, Zheng N, Wu Z
International immunopharmacology 2018 Jul;60:111-120
International immunopharmacology 2018 Jul;60:111-120
Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice.
Wang N, Liu Y, Ma Y, Wen D
The Journal of nutritional biochemistry 2018 Jul;57:180-188
The Journal of nutritional biochemistry 2018 Jul;57:180-188
Tumor necrosis factor receptor-associated factor 6 mediated the promotion of salivary adenoid cystic carcinoma progression through Smad-p38-JNK signaling pathway induced by TGF-β.
Liang Y, Jiao J, Liang L, Zhang J, Lu Y, Xie H, Liang Q, Wan D, Duan L, Wu Y, Zhang B
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Jul;47(6):583-589
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Jul;47(6):583-589
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Ci Y, Zhang Y, Liu Y, Lu S, Cao J, Li H, Zhang J, Huang Z, Zhu X, Gao J, Han M
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, Geng S, Wu J, Zhang Q, Wang X, Meng Y, Li Y, Chen Y, Cao W, Wang X, Zhong C, Li X
Toxicology letters 2018 Jul;291:70-76
Toxicology letters 2018 Jul;291:70-76
Interferon-induced protein 35 inhibits endothelial cell proliferation, migration and re-endothelialization of injured arteries by inhibiting the nuclear factor-kappa B pathway.
Jian D, Wang W, Zhou X, Jia Z, Wang J, Yang M, Zhao W, Jiang Z, Hu X, Zhu J
Acta physiologica (Oxford, England) 2018 Jul;223(3):e13037
Acta physiologica (Oxford, England) 2018 Jul;223(3):e13037
Icariside II alleviates oxygen-glucose deprivation and reoxygenation-induced PC12 cell oxidative injury by activating Nrf2/SIRT3 signaling pathway.
Feng L, Gao J, Liu Y, Shi J, Gong Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:9-17
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:9-17
Long non-coding RNA CRNDE promotes heptaocellular carcinoma cell proliferation by regulating PI3K/Akt /β-catenin signaling.
Tang Q, Zheng X, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1187-1193
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1187-1193
Adoptive Transfer of Interleukin-21-stimulated Human CD8+ T Memory Stem Cells Efficiently Inhibits Tumor Growth.
Chen Y, Yu F, Jiang Y, Chen J, Wu K, Chen X, Lin Y, Zhang H, Li L, Zhang Y
Journal of immunotherapy (Hagerstown, Md. : 1997) 2018 Jul Aug;41(6):274-283
Journal of immunotherapy (Hagerstown, Md. : 1997) 2018 Jul Aug;41(6):274-283
The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20.
Yu X, Yuan Z, Yang Z, Chen D, Kim T, Cui Y, Luo Q, Liu Z, Yang Z, Fan X, Chen D, Wang L
Cell death & disease 2018 Jul 3;9(7):751
Cell death & disease 2018 Jul 3;9(7):751
LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling.
Zhang S, Ma H, Zhang D, Xie S, Wang W, Li Q, Lin Z, Wang Y
Cell death & disease 2018 Jul 3;9(7):742
Cell death & disease 2018 Jul 3;9(7):742
Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction.
Liu Q, Zhao H, Gao Y, Meng Y, Zhao XX, Pan SN
Chinese medical journal 2018 Jul 20;131(14):1724-1731
Chinese medical journal 2018 Jul 20;131(14):1724-1731
The Role of the RhoA/ROCK Signaling Pathway in Mechanical Strain-Induced Scleral Myofibroblast Differentiation.
Yuan Y, Li M, To CH, Lam TC, Wang P, Yu Y, Chen Q, Hu X, Ke B
Investigative ophthalmology & visual science 2018 Jul 2;59(8):3619-3629
Investigative ophthalmology & visual science 2018 Jul 2;59(8):3619-3629
Conditioned medium from overly excitatory primary astrocytes induced by La(3+) increases apoptosis in primary neurons via upregulating the expression of NMDA receptors.
Sun Y, Yang J, Hu X, Gao X, Li Y, Yu M, Liu S, Lu Y, Wang J, Huang L, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2018 Jul 18;10(7):1016-1028
Metallomics : integrated biometal science 2018 Jul 18;10(7):1016-1028
Cell-laden and orthogonal-multilayer tissue-engineered corneal stroma induced by a mechanical collagen microenvironment and transplantation in a rabbit model.
Cui Z, Zeng Q, Liu S, Zhang Y, Zhu D, Guo Y, Xie M, Mathew S, Cai D, Zhang J, Chen J
Acta biomaterialia 2018 Jul 15;75:183-199
Acta biomaterialia 2018 Jul 15;75:183-199
Loss of MED12 Induces Tumor Dormancy in Human Epithelial Ovarian Cancer via Downregulation of EGFR.
Luo XL, Deng CC, Su XD, Wang F, Chen Z, Wu XP, Liang SB, Liu JH, Fu LW
Cancer research 2018 Jul 1;78(13):3532-3543
Cancer research 2018 Jul 1;78(13):3532-3543
Cancer-associated fibroblasts confer cisplatin resistance of tongue cancer via autophagy activation.
Liao JK, Zhou B, Zhuang XM, Zhuang PL, Zhang DM, Chen WL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1341-1348
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1341-1348
UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis.
Liu C, Xing J, Gao Y
Thoracic cancer 2018 Jan;9(1):105-111
Thoracic cancer 2018 Jan;9(1):105-111
P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population.
Zhou Y, Tan CY, Mo ZJ, Gao QL, He D, Li J, Huang RF, Li YB, Guo CF, Guo Q, Wang LJ, Yang GT, Zhang HQ
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2018 Jan;57:138-144
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2018 Jan;57:138-144
AMPK/NF-κB signaling pathway regulated by ghrelin participates in the regulation of HUVEC and THP1 Inflammation.
Zhang M, Wang S, Pan Z, Ou T, Ma J, Liu H, Li R, Yang P, Han W, Guan S, Hou X, Fang W, Qu X
Molecular and cellular biochemistry 2018 Jan;437(1-2):45-53
Molecular and cellular biochemistry 2018 Jan;437(1-2):45-53
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y
International journal of molecular medicine 2018 Jan;41(1):430-438
International journal of molecular medicine 2018 Jan;41(1):430-438
Development of chondrocyte-seeded electrosprayed nanoparticles for repair of articular cartilage defects in rabbits.
Yang SW, Ku KC, Chen SY, Kuo SM, Chen IF, Wang TY, Chang SJ
Journal of biomaterials applications 2018 Jan;32(6):800-812
Journal of biomaterials applications 2018 Jan;32(6):800-812
GM13133 is a negative regulator in mouse white adipocytes differentiation and drives the characteristics of brown adipocytes.
You L, Zhou Y, Cui X, Wang X, Sun Y, Gao Y, Wang X, Wen J, Xie K, Tang R, Ji C, Guo X
Journal of cellular physiology 2018 Jan;233(1):313-324
Journal of cellular physiology 2018 Jan;233(1):313-324
UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway.
He D, Zhang S
Molecular medicine reports 2018 Jan;17(1):549-555
Molecular medicine reports 2018 Jan;17(1):549-555
Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity.
Wang H, Wang H, Liang EY, Zhou LX, Dong ZL, Liang P, Weng QF, Yang M
Oncology letters 2018 Jan;15(1):839-848
Oncology letters 2018 Jan;15(1):839-848
Salidroside attenuates hypoxia/reoxygenation-induced human brain vascular smooth muscle cell injury by activating the SIRT1/FOXO3α pathway.
Xu L, Jia L, Wang Q, Hou J, Li S, Teng J
Experimental and therapeutic medicine 2018 Jan;15(1):822-830
Experimental and therapeutic medicine 2018 Jan;15(1):822-830
MicroRNA-144 inhibits proliferation by targeting WW domain-containing transcription regulator protein 1 in papillary thyroid cancer.
Sun W, Lan X, Wang Z, Dong W, He L, Zhang T, Zhang P, Zhang H
Oncology letters 2018 Jan;15(1):1007-1013
Oncology letters 2018 Jan;15(1):1007-1013
Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.
Luo W, Zhang J, Liang L, Wang G, Li Q, Zhu P, Zhou Y, Li J, Zhao Y, Sun N, Huang S, Zhou C, Chang Y, Cui P, Chen P, Jiang Y, Deng G, Bu Z, Li C, Jiang L, Chen H
PLoS pathogens 2018 Jan;14(1):e1006851
PLoS pathogens 2018 Jan;14(1):e1006851
Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma.
Zhou L, Chen HM, Qu S, Li L, Zhao W, Liang ZG, Yu BB, Chen KH, Lu QT, Lin GX, Zhu XD
Oncotarget 2018 Jan 9;9(3):3230-3241
Oncotarget 2018 Jan 9;9(3):3230-3241
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
Goncalves MD, Hwang SK, Pauli C, Murphy CJ, Cheng Z, Hopkins BD, Wu D, Loughran RM, Emerling BM, Zhang G, Fearon DT, Cantley LC
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 23;115(4):E743-E752
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 23;115(4):E743-E752
ZEB1 stimulates breast cancer growth by up-regulating hTERT expression.
Yu P, Shen X, Yang W, Zhang Y, Liu C, Huang T
Biochemical and biophysical research communications 2018 Jan 22;495(4):2505-2511
Biochemical and biophysical research communications 2018 Jan 22;495(4):2505-2511
Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy.
Jimenez-Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, Steinberg F
The EMBO journal 2018 Jan 17;37(2):235-254
The EMBO journal 2018 Jan 17;37(2):235-254
miR-21 modulates prostaglandin signaling and promotes gastric tumorigenesis by targeting 15-PGDH.
Li L, Wang X, Li W, Yang L, Liu R, Zeng R, Wu Y, Shou T
Biochemical and biophysical research communications 2018 Jan 1;495(1):928-934
Biochemical and biophysical research communications 2018 Jan 1;495(1):928-934
Evaluation of vitrification protocol of mouse ovarian tissue by effect of DNA methyltransferase-1 and paternal imprinted growth factor receptor-binding protein 10 on signaling pathways.
He ZY, Wang HY, Zhou X, Liang XY, Yan B, Wang R, Ma LH, Wang YL
Cryobiology 2018 Feb;80:89-95
Cryobiology 2018 Feb;80:89-95
Tip60 is associated with resistance to X-ray irradiation in prostate cancer.
Xie X, Xu Z, Wang C, Fang C, Zhao J, Xu L, Qian X, Dai J, Sun F, Xu D, He W
FEBS open bio 2018 Feb;8(2):271-278
FEBS open bio 2018 Feb;8(2):271-278
Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway.
Wang Q, Yang K, Han B, Sheng B, Yin J, Pu A, Li L, Sun L, Yu M, Qiu Y, Xiao W, Yang H
International journal of molecular medicine 2018 Feb;41(2):868-876
International journal of molecular medicine 2018 Feb;41(2):868-876
Influence of patterned titanium coatings on polarization of macrophage and osteogenic differentiation of bone marrow stem cells.
Zhang Z, Xie Y, Pan H, Huang L, Zheng X
Journal of biomaterials applications 2018 Feb;32(7):977-986
Journal of biomaterials applications 2018 Feb;32(7):977-986
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Xie Y, Wen H, Yan K, Wang S, Wang X, Chen J, Li Y, Xu Y, Zhong Z, Shen J, Chu D
Cellular & molecular immunology 2018 Feb;15(2):120-134
Cellular & molecular immunology 2018 Feb;15(2):120-134
Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking.
Cervero P, Wiesner C, Bouissou A, Poincloux R, Linder S
Nature communications 2018 Feb 6;9(1):515
Nature communications 2018 Feb 6;9(1):515
FAK-ERK activation in cell/matrix adhesion induced by the loss of apolipoprotein E stimulates the malignant progression of ovarian cancer.
Lai H, Zhao X, Qin Y, Ding Y, Chen R, Li G, Labrie M, Ding Z, Zhou J, Hu J, Ma D, Fang Y, Gao Q
Journal of experimental & clinical cancer research : CR 2018 Feb 20;37(1):32
Journal of experimental & clinical cancer research : CR 2018 Feb 20;37(1):32
Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial Cells.
He J, Bao Q, Zhang Y, Liu M, Lv H, Liu Y, Yao L, Li B, Zhang C, He S, Zhai G, Zhu Y, Liu X, Zhang K, Wang XJ, Zou MH, Zhu Y, Ai D
Circulation research 2018 Feb 16;122(4):591-605
Circulation research 2018 Feb 16;122(4):591-605
CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency.
Brockmann SJ, Freischmidt A, Oeckl P, Müller K, Ponna SK, Helferich AM, Paone C, Reinders J, Kojer K, Orth M, Jokela M, Auranen M, Udd B, Hermann A, Danzer KM, Lichtner P, Walther P, Ludolph AC, Andersen PM, Otto M, Kursula P, Just S, Weishaupt JH
Human molecular genetics 2018 Feb 15;27(4):706-715
Human molecular genetics 2018 Feb 15;27(4):706-715
Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats.
Yao X, Xia F, Tang W, Xiao C, Yang M, Zhou B
Journal of ethnopharmacology 2018 Feb 15;212:208-215
Journal of ethnopharmacology 2018 Feb 15;212:208-215
Coupling of oxidative stress responses to tricarboxylic acid cycle and prostaglandin E(2) alterations in Caenorhabditis elegans under extremely low-frequency electromagnetic field.
Sun Y, Shi Z, Wang Y, Tang C, Liao Y, Yang C, Cai P
International journal of radiation biology 2018 Dec;94(12):1159-1166
International journal of radiation biology 2018 Dec;94(12):1159-1166
Blocking FGFR4 exerts distinct anti-tumorigenic effects in esophageal squamous cell carcinoma.
Xin Z, Song X, Jiang B, Gongsun X, Song L, Qin Q, Wang Q, Shi M, Liu X
Thoracic cancer 2018 Dec;9(12):1687-1698
Thoracic cancer 2018 Dec;9(12):1687-1698
Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS.
Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, Weishaupt JH
Cellular and molecular life sciences : CMLS 2018 Dec;75(23):4301-4319
Cellular and molecular life sciences : CMLS 2018 Dec;75(23):4301-4319
Inhibition of mTORC2 enhances UVB-induced apoptosis in keratinocytes through a mechanism dependent on the FOXO3a transcriptional target NOXA but independent of TRAIL.
Feehan RP, Nelson AM, Shantz LM
Cellular signalling 2018 Dec;52:35-47
Cellular signalling 2018 Dec;52:35-47
The effect of NR4A1 on APP metabolism and tau phosphorylation.
Zhao LG, Tang Y, Tan JZ, Wang JW, Chen GJ, Zhu BL
Genes & diseases 2018 Dec;5(4):342-348
Genes & diseases 2018 Dec;5(4):342-348
Low-Intensity Pulsed Ultrasound Treatment Accelerates Angiogenesis by Activating YAP/TAZ in Human Umbilical Vein Endothelial Cells.
Xu XM, Xu TM, Wei YB, Gao XX, Sun JC, Wang Y, Kong QJ, Shi JG
Ultrasound in medicine & biology 2018 Dec;44(12):2655-2661
Ultrasound in medicine & biology 2018 Dec;44(12):2655-2661
Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush.
Ding D, Zhang P, Liu Y, Wang Y, Sun W, Yu Z, Cheng Z, Wang Y
Neurochemical research 2018 Dec;43(12):2423-2434
Neurochemical research 2018 Dec;43(12):2423-2434
SFMBT2 positively regulates SOX9 and chondrocyte proliferation.
Hussain S, Sun M, Guo Y, Mushtaq N, Zhao Y, Yuan Y, Hussain N, Osoro E, Suleiman A, Sadiq M, Zhang F, Han Y, Sun J, Lu S
International journal of molecular medicine 2018 Dec;42(6):3503-3512
International journal of molecular medicine 2018 Dec;42(6):3503-3512
Aspirin promotes apoptosis and inhibits proliferation by blocking G0/G1 into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway.
Zhang X, Feng H, Du J, Sun J, Li D, Hasegawa T, Amizuka N, Li M
International journal of molecular medicine 2018 Dec;42(6):3135-3148
International journal of molecular medicine 2018 Dec;42(6):3135-3148
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Liu J, Lv X, Dong W, Hu M, Xu J, Qian G, Li Y
Inflammation 2018 Dec;41(6):2222-2235
Inflammation 2018 Dec;41(6):2222-2235
Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer.
Wu JS, Li L, Wang SS, Pang X, Wu JB, Sheng SR, Tang YJ, Tang YL, Zheng M, Liang XH
Oncology reports 2018 Dec;40(6):3381-3391
Oncology reports 2018 Dec;40(6):3381-3391
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Fang X, Liu Y, Lu J, Hong H, Yuan J, Zhang Y, Wang P, Liu P, Ye J
Naunyn-Schmiedeberg's archives of pharmacology 2018 Dec;391(12):1373-1385
Naunyn-Schmiedeberg's archives of pharmacology 2018 Dec;391(12):1373-1385
Elevating ATP-binding cassette transporter G1 improves re-endothelialization function of endothelial progenitor cells via Lyn/Akt/eNOS in diabetic mice.
Shi Y, Lv X, Liu Y, Li B, Liu M, Yan M, Liu Y, Li Q, Zhang X, He S, Zhu M, He J, Zhu Y, Zhu Y, Ai D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Dec;32(12):6525-6536
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Dec;32(12):6525-6536
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Li Y, Fu S, Li E, Sun X, Xu H, Meng Y, Wang X, Chen Y, Xie C, Geng S, Wu J, Zhong C, Xu P
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
An androgen receptor negatively induced long non-coding RNA ARNILA binding to miR-204 promotes the invasion and metastasis of triple-negative breast cancer.
Yang F, Shen Y, Zhang W, Jin J, Huang D, Fang H, Ji W, Shi Y, Tang L, Chen W, Zhou G, Guan X
Cell death and differentiation 2018 Dec;25(12):2209-2220
Cell death and differentiation 2018 Dec;25(12):2209-2220
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
Deng G, Li K, Chen S, Chen P, Zheng H, Yu B, Zhang K
Molecular medicine reports 2018 Dec;18(6):5044-5052
Molecular medicine reports 2018 Dec;18(6):5044-5052
Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.
Lee K, Haddad A, Osme A, Kim C, Borzou A, Ilchenko S, Allende D, Dasarathy S, McCullough A, Sadygov RG, Kasumov T
Molecular & cellular proteomics : MCP 2018 Dec;17(12):2371-2386
Molecular & cellular proteomics : MCP 2018 Dec;17(12):2371-2386
The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus.
Wu Q, Wang H
Epilepsy research 2018 Dec;148:8-16
Epilepsy research 2018 Dec;148:8-16
Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.
Li X, Wu J, Zhang X, Chen W
Free radical biology & medicine 2018 Dec;129:256-267
Free radical biology & medicine 2018 Dec;129:256-267
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Yan L, You WQ, Sheng NQ, Gong JF, Hu LD, Tan GW, Chen HQ, Wang ZG
Aging 2018 Dec 6;10(12):3774-3793
Aging 2018 Dec 6;10(12):3774-3793
Hepatoprotective Effect of Baicalein Against Acetaminophen-Induced Acute Liver Injury in Mice.
Zhou HC, Wang H, Shi K, Li JM, Zong Y, Du R
Molecules (Basel, Switzerland) 2018 Dec 31;24(1)
Molecules (Basel, Switzerland) 2018 Dec 31;24(1)
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, Han Y, Li L, Li Q
Chemico-biological interactions 2018 Dec 25;296:145-153
Chemico-biological interactions 2018 Dec 25;296:145-153
CD36 plays a critical role in proliferation, migration and tamoxifen-inhibited growth of ER-positive breast cancer cells.
Liang Y, Han H, Liu L, Duan Y, Yang X, Ma C, Zhu Y, Han J, Li X, Chen Y
Oncogenesis 2018 Dec 21;7(12):98
Oncogenesis 2018 Dec 21;7(12):98
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Han H, Yang S, Liang Y, Zeng P, Liu L, Yang X, Duan Y, Han J, Chen Y
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1.
Wen ZF, Liu H, Gao R, Zhou M, Ma J, Zhang Y, Zhao J, Chen Y, Zhang T, Huang F, Pan N, Zhang J, Fox BA, Hu HM, Wang LX
Journal for immunotherapy of cancer 2018 Dec 18;6(1):151
Journal for immunotherapy of cancer 2018 Dec 18;6(1):151
Atypical Gasdermin D and Mixed Lineage Kinase Domain-like Protein Leakage Aggravates Tetrachlorobenzoquinone-Induced Nod-like Receptor Protein 3 Inflammasome Activation.
Xia X, Lu B, Dong W, Yang B, Wang Y, Qin Q, Liu Z, Song E, Song Y
Chemical research in toxicology 2018 Dec 17;31(12):1418-1425
Chemical research in toxicology 2018 Dec 17;31(12):1418-1425
Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
Hu M, Liu L, Yao W
Gene 2018 Dec 15;678:261-269
Gene 2018 Dec 15;678:261-269
Arsenite renal apoptotic effects in chickens co-aggravated by oxidative stress and inflammatory response.
Wang Y, Zhao H, Guo M, Shao Y, Liu J, Jiang G, Xing M
Metallomics : integrated biometal science 2018 Dec 12;10(12):1805-1813
Metallomics : integrated biometal science 2018 Dec 12;10(12):1805-1813
Sulfur dioxide attenuates sepsis-induced cardiac dysfunction via inhibition of NLRP3 inflammasome activation in rats.
Yang L, Zhang H, Chen P
Nitric oxide : biology and chemistry 2018 Dec 1;81:11-20
Nitric oxide : biology and chemistry 2018 Dec 1;81:11-20
Characterization of Divalent Metal Transporter 1 (DMT1) in Brugia malayi suggests an intestinal-associated pathway for iron absorption.
Ballesteros C, Geary JF, Mackenzie CD, Geary TG
International journal for parasitology. Drugs and drug resistance 2018 Aug;8(2):341-349
International journal for parasitology. Drugs and drug resistance 2018 Aug;8(2):341-349
Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms.
Kumar S, Wang G, Liu W, Ding W, Dong M, Zheng N, Ye H, Liu J
Hypertension (Dallas, Tex. : 1979) 2018 Aug;72(2):331-342
Hypertension (Dallas, Tex. : 1979) 2018 Aug;72(2):331-342
Eukaryotic translation initiation factor EIF3H potentiates gastric carcinoma cell proliferation.
Wang X, Wang H, Zhao S, Sun P, Wen D, Liu T, Liu H, Yang Z, Ma Z
Tissue & cell 2018 Aug;53:23-29
Tissue & cell 2018 Aug;53:23-29
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
Li Y, Wang X, Zhang L, Yuan X, Hao J, Ni J, Hao L
International journal of molecular medicine 2018 Aug;42(2):861-872
International journal of molecular medicine 2018 Aug;42(2):861-872
A novel biphenyl urea compound, TPD7, stimulates apoptosis through modulating Fas signaling and Bcl-2 family proteins in cervical cancer.
Zhan Y, Zhang H, Dai B, Zhang Y, Zhang J, He L
Oncology reports 2018 Aug;40(2):1064-1072
Oncology reports 2018 Aug;40(2):1064-1072
Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.
Ji J, Xue TF, Guo XD, Yang J, Guo RB, Wang J, Huang JY, Zhao XJ, Sun XL
Aging cell 2018 Aug;17(4):e12774
Aging cell 2018 Aug;17(4):e12774
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
Dai H, Deng HB, Wang YH, Guo JJ
Oncology letters 2018 Aug;16(2):1579-1583
Oncology letters 2018 Aug;16(2):1579-1583
MicroRNA-379 suppresses cell proliferation, migration and invasion in nasopharyngeal carcinoma by targeting tumor protein D52.
Zhao X, Chu J
Experimental and therapeutic medicine 2018 Aug;16(2):1232-1240
Experimental and therapeutic medicine 2018 Aug;16(2):1232-1240
Disulfiram/copper targets stem cell-like ALDH(+) population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway.
Jin N, Zhu X, Cheng F, Zhang L
Journal of cellular biochemistry 2018 Aug;119(8):6882-6893
Journal of cellular biochemistry 2018 Aug;119(8):6882-6893
AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.
Zheng Q, Yang Y, Cui X, Zhang D, Liu S, Yan Q
Journal of cellular biochemistry 2018 Aug;119(8):6442-6451
Journal of cellular biochemistry 2018 Aug;119(8):6442-6451
Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR-196a-5p.
Li S, Zhou J, Wang Z, Wang P, Gao X, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:451-457
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:451-457
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
Ke M, Dong J, Wang Y, Zhang J, Zhang M, Wu Z, Lv Y, Wu R
The international journal of biochemistry & cell biology 2018 Aug;101:39-48
The international journal of biochemistry & cell biology 2018 Aug;101:39-48
ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.
Ma S, Lu CC, Yang LY, Wang JJ, Wang BS, Cai HQ, Hao JJ, Xu X, Cai Y, Zhang Y, Wang MR
Journal of experimental & clinical cancer research : CR 2018 Aug 6;37(1):183
Journal of experimental & clinical cancer research : CR 2018 Aug 6;37(1):183
Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.
Wu W, Wang S, Liu Q, Shan T, Wang Y
Molecular pharmaceutics 2018 Aug 6;15(8):3272-3284
Molecular pharmaceutics 2018 Aug 6;15(8):3272-3284
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Zhang D, Sun X, Ren L, Yang C, Liu X, Zhang H, Jiang Y, Hu X
Journal of proteomics 2018 Aug 30;186:28-37
Journal of proteomics 2018 Aug 30;186:28-37
Deletion of MBD2 inhibits proliferation of chronic myeloid leukaemia blast phase cells.
Cheng L, Tang Y, Chen X, Zhao L, Liu S, Ma Y, Wang N, Zhou K, Zhou J, Zhou M
Cancer biology & therapy 2018 Aug 3;19(8):676-686
Cancer biology & therapy 2018 Aug 3;19(8):676-686
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390
Nature communications 2018 Aug 23;9(1):3390
MEF2A regulates Calpain 3 expression in L6 myoblasts.
Wu R, Wang J, Yao J, Dong Z, Liu Y, Liu M
Gene 2018 Aug 20;668:204-210
Gene 2018 Aug 20;668:204-210
Expression of Concern: Knockdown of eIF3d inhibits cell proliferation through G2/M phase arrest in non-small cell lung cancer.
Lin Z, Xiong L, Lin Q
Medical oncology (Northwood, London, England) 2018 Aug 18;35(10):130
Medical oncology (Northwood, London, England) 2018 Aug 18;35(10):130
Therapeutic effects of recombinant human S100A6 and soluble receptor for advanced glycation end products(sRAGE) on CCl(4)-induced liver fibrosis in mice.
Xia P, He H, Kristine MS, Guan W, Gao J, Wang Z, Hu J, Han L, Li J, Han W, Yu Y
European journal of pharmacology 2018 Aug 15;833:86-93
European journal of pharmacology 2018 Aug 15;833:86-93
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Huang X, Wu H, Jiang R, Sun G, Shen J, Ma M, Ma C, Zhang S, Huang Z, Wu Q, Chen G, Tao W
European journal of pharmacology 2018 Aug 15;833:1-7
European journal of pharmacology 2018 Aug 15;833:1-7
Triptolide inhibits Epstein-Barr nuclear antigen 1 expression by increasing sensitivity of mitochondria apoptosis of nasopharyngeal carcinoma cells.
Zhou H, Liu Y, Wang C, Liu L, Wang H, Zhang Y, Long C, Sun X
Journal of experimental & clinical cancer research : CR 2018 Aug 15;37(1):192
Journal of experimental & clinical cancer research : CR 2018 Aug 15;37(1):192
MSX2 Initiates and Accelerates Mesenchymal Stem/Stromal Cell Specification of hPSCs by Regulating TWIST1 and PRAME.
Zhang L, Wang H, Liu C, Wu Q, Su P, Wu D, Guo J, Zhou W, Xu Y, Shi L, Zhou J
Stem cell reports 2018 Aug 14;11(2):497-513
Stem cell reports 2018 Aug 14;11(2):497-513
A Scalable and Efficient Bioprocess for Manufacturing Human Pluripotent Stem Cell-Derived Endothelial Cells.
Lin H, Du Q, Li Q, Wang O, Wang Z, Sahu N, Elowsky C, Liu K, Zhang C, Chung S, Duan B, Lei Y
Stem cell reports 2018 Aug 14;11(2):454-469
Stem cell reports 2018 Aug 14;11(2):454-469
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Meng M, Chen Y, Jia J, Li L, Yang S
Biological research 2018 Aug 10;51(1):24
Biological research 2018 Aug 10;51(1):24
Ultrastructural Characterization of Corticotropin-Releasing Factor and Neuropeptide Y in the Rat Locus Coeruleus: Anatomical Evidence for Putative Interactions.
Theisen CC, Reyes BAS, Sabban EL, Van Bockstaele EJ
Neuroscience 2018 Aug 1;384:21-40
Neuroscience 2018 Aug 1;384:21-40
MicroRNA-466 (miR-466) functions as a tumor suppressor and prognostic factor in colorectal cancer (CRC).
Tong F, Ying Y, Pan H, Zhao W, Li H, Zhan X
Bosnian journal of basic medical sciences 2018 Aug 1;18(3):252-259
Bosnian journal of basic medical sciences 2018 Aug 1;18(3):252-259
Exogenous H(2)S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Sun Y, Tian Z, Liu N, Zhang L, Gao Z, Sun X, Yu M, Wu J, Yang F, Zhao Y, Ren H, Chen H, Zhao D, Wang Y, Dong S, Xu C, Lu F, Zhang W
Journal of molecular medicine (Berlin, Germany) 2018 Apr;96(3-4):281-299
Journal of molecular medicine (Berlin, Germany) 2018 Apr;96(3-4):281-299
Extract of Euryale ferox Salisb exerts antidepressant effects and regulates autophagy through the adenosine monophosphate-activated protein kinase-UNC-51-like kinase 1 pathway.
Huang Z, Huang X, Wang Q, Jiang R, Sun G, Xu Y, Wu Q
IUBMB life 2018 Apr;70(4):300-309
IUBMB life 2018 Apr;70(4):300-309
TRIM28 promotes cervical cancer growth through the mTOR signaling pathway.
Li F, Wang Z, Lu G
Oncology reports 2018 Apr;39(4):1860-1866
Oncology reports 2018 Apr;39(4):1860-1866
Vitamin D attenuates pressure overload-induced cardiac remodeling and dysfunction in mice.
Zhang L, Yan X, Zhang YL, Bai J, Hidru TH, Wang QS, Li HH
The Journal of steroid biochemistry and molecular biology 2018 Apr;178:293-302
The Journal of steroid biochemistry and molecular biology 2018 Apr;178:293-302
Gli family zinc finger 1 is associated with endothelin receptor type B in Hirschsprung disease.
Liu W, Pan J, Gao J, Shuai X, Tang S, Wang G, Tao K, Wu C
Molecular medicine reports 2018 Apr;17(4):5844-5850
Molecular medicine reports 2018 Apr;17(4):5844-5850
Cullin7 promotes epithelial‑mesenchymal transition of esophageal carcinoma via the ERK‑SNAI2 signaling pathway.
Tian P, Liu D, Sun L, Sun H
Molecular medicine reports 2018 Apr;17(4):5362-5367
Molecular medicine reports 2018 Apr;17(4):5362-5367
Liraglutide inhibits the proliferation and promotes the apoptosis of MCF-7 human breast cancer cells through downregulation of microRNA-27a expression.
Zhao W, Zhang X, Zhou Z, Sun B, Gu W, Liu J, Zhang H
Molecular medicine reports 2018 Apr;17(4):5202-5212
Molecular medicine reports 2018 Apr;17(4):5202-5212
Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway.
Zhang H, Cao Y, Chen Y, Li G, Yu H
Oncology letters 2018 Apr;15(4):5739-5743
Oncology letters 2018 Apr;15(4):5739-5743
Downregulation of ubiquitin-specific peptidase 39 suppresses the proliferation and induces the apoptosis of human colorectal cancer cells.
Xing Z, Sun F, He W, Wang Z, Song X, Zhang F
Oncology letters 2018 Apr;15(4):5443-5450
Oncology letters 2018 Apr;15(4):5443-5450
Overexpression of MYC binding protein promotes invasion and migration in gastric cancer.
Gong L, Xia Y, Qian Z, Shi J, Luo J, Song G, Xu J, Ye Z
Oncology letters 2018 Apr;15(4):5243-5249
Oncology letters 2018 Apr;15(4):5243-5249
Sulfur dioxide improves endothelial dysfunction by downregulating the angiotensin II/AT(1)R pathway in D-galactose-induced aging rats.
Dai J, Liu R, Zhao J, Zhang A
Journal of the renin-angiotensin-aldosterone system : JRAAS 2018 Apr-Jun;19(2):1470320318778898
Journal of the renin-angiotensin-aldosterone system : JRAAS 2018 Apr-Jun;19(2):1470320318778898
Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity.
Yang T, Wang Y, Dai W, Zheng X, Wang J, Song S, Fang L, Zhou J, Wu W, Gu J
Journal of hematology & oncology 2018 Apr 4;11(1):50
Journal of hematology & oncology 2018 Apr 4;11(1):50
C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation.
Liu D, Zhang XX, Li MC, Cao CH, Wan DY, Xi BX, Tan JH, Wang J, Yang ZY, Feng XX, Ye F, Chen G, Wu P, Xi L, Wang H, Zhou JF, Feng ZH, Ma D, Gao QL
Nature communications 2018 Apr 30;9(1):1739
Nature communications 2018 Apr 30;9(1):1739
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Yin S, Du W, Wang F, Han B, Cui Y, Yang D, Chen H, Liu D, Liu X, Zhai X, Jiang C
Cancer biology & therapy 2018 Apr 3;19(4):260-270
Cancer biology & therapy 2018 Apr 3;19(4):260-270
Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy.
Qiu Y, Yu Q, Liu Y, Tang J, Wang X, Lu Z, Xu Z, He Q
Pharmaceutical research 2018 Apr 26;35(7):130
Pharmaceutical research 2018 Apr 26;35(7):130
Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer.
Jiang CF, Shi ZM, Li DM, Qian YC, Ren Y, Bai XM, Xie YX, Wang L, Ge X, Liu WT, Zhen LL, Liu LZ, Jiang BH
Molecular cancer 2018 Apr 23;17(1):83
Molecular cancer 2018 Apr 23;17(1):83
Brca1 Is Upregulated by 5-Aza-CdR and Promotes DNA Repair and Cell Survival, and Inhibits Neurite Outgrowth in Rat Retinal Neurons.
Wang Q, Xu L, Chen P, Xu Z, Qiu J, Ge J, Yu K, Zhuang J
International journal of molecular sciences 2018 Apr 17;19(4)
International journal of molecular sciences 2018 Apr 17;19(4)
MCPIP1 is a positive regulator of type I interferons antiviral activity.
Qian L, Zuo Y, Deng W, Miao Y, Liu J, Yuan Y, Guo T, Zhang L, Jin J, Wang J, Zheng H
Biochemical and biophysical research communications 2018 Apr 15;498(4):891-897
Biochemical and biophysical research communications 2018 Apr 15;498(4):891-897
Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization.
Tang M, Yang Y, Yu J, Qiu J, Chen P, Wu Y, Wang Q, Xu Z, Ge J, Yu K, Zhuang J
Investigative ophthalmology & visual science 2018 Apr 1;59(5):2133-2141
Investigative ophthalmology & visual science 2018 Apr 1;59(5):2133-2141
Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats.
Cao M, Fang J, Wang X, Wang Y, Duan K, Ye F, Ouyang W, Tong J
Brain research 2018 Apr 1;1684:21-29
Brain research 2018 Apr 1;1684:21-29
Astrocytes mediated the nootropic and neurotrophic effects of Sarsasapogenin-AA13 via upregulating brain-derived neurotrophic factor.
Dong D, Mao Y, Huang C, Jiao Q, Pan H, Ma L, Wang R
American journal of translational research 2017;9(9):4015-4025
American journal of translational research 2017;9(9):4015-4025
Porphyromonas gingivalis and its lipopolysaccharide differently modulate epidermal growth factor-dependent signaling in human gingival epithelial cells.
Elkaim R, Bugueno-Valdebenito IM, Benkirane-Jessel N, Tenenbaum H
Journal of oral microbiology 2017;9(1):1334503
Journal of oral microbiology 2017;9(1):1334503
Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome.
Wang H, Zhang TT, Jin S, Liu H, Zhang X, Ruan CG, Wu DP, Han Y, Wang XQ
Clinical epigenetics 2017;9:91
Clinical epigenetics 2017;9:91
Overexpression of SMOC2 Attenuates the Tumorigenicity of Hepatocellular Carcinoma Cells and Is Associated With a Positive Postoperative Prognosis in Human Hepatocellular Carcinoma.
Huang XQ, Zhou ZQ, Zhang XF, Chen CL, Tang Y, Zhu Q, Zhang JH, Xia JC
Journal of Cancer 2017;8(18):3812-3827
Journal of Cancer 2017;8(18):3812-3827
USP22 Induces Cisplatin Resistance in Lung Adenocarcinoma by Regulating γH2AX-Mediated DNA Damage Repair and Ku70/Bax-Mediated Apoptosis.
Wang A, Ning Z, Lu C, Gao W, Liang J, Yan Q, Tan G, Liu J
Frontiers in pharmacology 2017;8:274
Frontiers in pharmacology 2017;8:274
MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2.
Hussain T, Zhao D, Shah SZA, Wang J, Yue R, Liao Y, Sabir N, Yang L, Zhou X
Frontiers in immunology 2017;8:1915
Frontiers in immunology 2017;8:1915
Macrophages Polarized by Expression of ToxoGRA15(II) Inhibit Growth of Hepatic Carcinoma.
Li Y, Poppoe F, Chen J, Yu L, Deng F, Luo Q, Xu Y, Cai Y, Shen J
Frontiers in immunology 2017;8:137
Frontiers in immunology 2017;8:137
Elevated expression of serine/threonine phosphatase type 5 correlates with malignant proliferation in human osteosarcoma.
Han K, Gan Z, Lin S, Hu H, Shen Z, Min D
Acta biochimica Polonica 2017;64(1):11-16
Acta biochimica Polonica 2017;64(1):11-16
MicroRNA-195 Suppresses the Progression of Pancreatic Cancer by Targeting DCLK1.
Zhou B, Sun C, Hu X, Zhan H, Zou H, Feng Y, Qiu F, Zhang S, Wu L, Zhang B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(5):1867-1881
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(5):1867-1881
Bufalin Inhibits Cellular Proliferation and Cancer Stem Cell-Like Phenotypes via Upregulation of MiR-203 in Glioma.
Liu T, Wu C, Weng G, Zhao Z, He X, Fu C, Sui Z, Huang SX
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):671-681
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):671-681
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Yu W, Li L, Zheng F, Yang W, Zhao S, Tian C, Yin W, Chen Y, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Effects of Trimetazidine on PDCD4/NF-κB/TNF-α Pathway in Coronary Microembolization.
Su Q, Li L, Zhao J, Sun Y, Yang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(2):753-760
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(2):753-760
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity.
Zhang QY, Wang ZJ, Sun DM, Wang Y, Xu P, Wu WJ, Liu XH, Zhu YZ
Oxidative medicine and cellular longevity 2017;2017:7150376
Oxidative medicine and cellular longevity 2017;2017:7150376
Santamarine Inhibits NF-κB Activation and Induces Mitochondrial Apoptosis in A549 Lung Adenocarcinoma Cells via Oxidative Stress.
Wu X, Zhu H, Yan J, Khan M, Yu X
BioMed research international 2017;2017:4734127
BioMed research international 2017;2017:4734127
Intracellular pH Regulates TRAIL-Induced Apoptosis and Necroptosis in Endothelial Cells.
Zhang ZX, Gan I, Pavlosky A, Huang X, Fuhrmann B, Jevnikar AM
Journal of immunology research 2017;2017:1503960
Journal of immunology research 2017;2017:1503960
MiR-20a-5p promotes radio-resistance by targeting Rab27B in nasopharyngeal cancer cells.
Huang D, Bian G, Pan Y, Han X, Sun Y, Wang Y, Shen G, Cheng M, Fang X, Hu S
Cancer cell international 2017;17:32
Cancer cell international 2017;17:32
The Crosstalk between HDPSCs and HUCMSCs on Proliferation and Osteogenic Genes Expression in Coculture System.
Jia L, Gu W, Zhang Y, Ji Y, Liang J, Wen Y, Xu X
International journal of medical sciences 2017;14(11):1118-1129
International journal of medical sciences 2017;14(11):1118-1129
Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age.
Tang Y, Wang X, Zhang S, Duan S, Qing W, Chen G, Ye F, Le Y, Ouyang W
PloS one 2017;12(8):e0182471
PloS one 2017;12(8):e0182471
RETRACTED: LncRNA-AF113014 promotes the expression of Egr2 by interaction with miR-20a to inhibit proliferation of hepatocellular carcinoma cells.
Zeng T, Wang D, Chen J, Tian Y, Cai X, Peng H, Zhu L, Huang A, Tang H
PloS one 2017;12(5):e0177843
PloS one 2017;12(5):e0177843
MiR-9-3p augments apoptosis induced by H2O2 through down regulation of Herpud1 in glioma.
Yang L, Mu Y, Cui H, Liang Y, Su X
PloS one 2017;12(4):e0174839
PloS one 2017;12(4):e0174839
Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice.
Zhang S, Wang X, Ai S, Ouyang W, Le Y, Tong J
PloS one 2017;12(11):e0188273
PloS one 2017;12(11):e0188273
Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion.
Yang Y, Lian S, Meng L, Qu L, Shou C
PloS one 2017;12(1):e0169665
PloS one 2017;12(1):e0169665
SIRT3 in Neural Stem Cells Attenuates Microglia Activation-Induced Oxidative Stress Injury Through Mitochondrial Pathway.
Jiang DQ, Wang Y, Li MX, Ma YJ, Wang Y
Frontiers in cellular neuroscience 2017;11:7
Frontiers in cellular neuroscience 2017;11:7
A modified approach to establish a murine model of hypoxic renal interstitial fibrosis.
Cheng Z, Limbu MH, Wang Z, Liu J, Liu L, Zhang X, Chen P
International journal of clinical and experimental pathology 2017;10(7):7991-7999
International journal of clinical and experimental pathology 2017;10(7):7991-7999
Electroacupuncture Alleviates Surgical Trauma-Induced Hypothalamus Pituitary Adrenal Axis Hyperactivity Via microRNA-142.
Zhu J, Chen Z, Meng Z, Ju M, Zhang M, Wu G, Guo H, Tian Z
Frontiers in molecular neuroscience 2017;10:308
Frontiers in molecular neuroscience 2017;10:308
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Zhao Z, Zhang L, Guo XD, Cao LL, Xue TF, Zhao XJ, Yang DD, Yang J, Ji J, Huang JY, Sun XL
Frontiers in molecular neuroscience 2017;10:293
Frontiers in molecular neuroscience 2017;10:293
SUN1 silencing inhibits cell growth through G0/G1 phase arrest in lung adenocarcinoma.
Huang W, Huang H, Wang L, Hu J, Song W
OncoTargets and therapy 2017;10:2825-2833
OncoTargets and therapy 2017;10:2825-2833
Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.
He T, Qiu T, Wang X, Gui H, Wang X, Hu Q, Xia H, Qi G, Wu J, Ma H
OncoTargets and therapy 2017;10:195-203
OncoTargets and therapy 2017;10:195-203
Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.
Ding M, Weng C, Fan S, Cao Q, Lu Z
Frontiers in molecular neuroscience 2017;10:121
Frontiers in molecular neuroscience 2017;10:121
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
Zhao N, Zhuo X, Lu Y, Dong Y, Ahmed ME, Tucker D, Scott EL, Zhang Q
Molecular neurobiology 2017 Sep;54(7):4936-4952
Molecular neurobiology 2017 Sep;54(7):4936-4952
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Zhang B, Liu Y, Liu D, Yang L
Journal of biosciences 2017 Sep;42(3):417-425
Journal of biosciences 2017 Sep;42(3):417-425
Myeloid differentiation factor 88 is up-regulated in epileptic brain and contributes to experimental seizures in rats.
Wang N, Han X, Liu H, Zhao T, Li J, Feng Y, Mi X, Zhang Y, Chen Y, Wang X
Experimental neurology 2017 Sep;295:23-35
Experimental neurology 2017 Sep;295:23-35
Anterior gradient 2 is induced in cutaneous wound and promotes wound healing through its adhesion domain.
Zhu Q, Mangukiya HB, Mashausi DS, Guo H, Negi H, Merugu SB, Wu Z, Li D
The FEBS journal 2017 Sep;284(17):2856-2869
The FEBS journal 2017 Sep;284(17):2856-2869
Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells.
Chuang TD, Khorram O
Reproductive sciences (Thousand Oaks, Calif.) 2017 Sep;24(9):1253-1263
Reproductive sciences (Thousand Oaks, Calif.) 2017 Sep;24(9):1253-1263
iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers.
Zhang H, Yang L, Liu Z, Liu C, Teng X, Zhang L, Yin B, Liu Z
Oncology letters 2017 Sep;14(3):3734-3740
Oncology letters 2017 Sep;14(3):3734-3740
Puerarin increases the chemosensitivity of hepatocellular carcinoma cells.
Wu Z, Wu J, Fang P, Kan S
Oncology letters 2017 Sep;14(3):3006-3010
Oncology letters 2017 Sep;14(3):3006-3010
The effect of CXCR2 inhibition on seizure activity in the pilocarpine epilepsy mouse model.
Xu T, Yu X, Wang T, Liu Y, Liu X, Ou S, Chen Y
Brain research bulletin 2017 Sep;134:91-98
Brain research bulletin 2017 Sep;134:91-98
Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection.
Fu Y, Zhang L, Zhang F, Tang T, Zhou Q, Feng C, Jin Y, Wu Z
PLoS pathogens 2017 Sep;13(9):e1006611
PLoS pathogens 2017 Sep;13(9):e1006611
LINC00052 upregulates EPB41L3 to inhibit migration and invasion of hepatocellular carcinoma by binding miR-452-5p.
Zhu L, Yang N, Chen J, Zeng T, Yan S, Liu Y, Yu G, Chen Q, Du G, Pan W, Li X, Zhou H, Huang A, Tang H
Oncotarget 2017 Sep 8;8(38):63724-63737
Oncotarget 2017 Sep 8;8(38):63724-63737
Effects of Chinese herbal medicines on the occurrence of diabetic retinopathy in type 2 diabetes patients and protection of ARPE-19 retina cells by inhibiting oxidative stress.
Tsai FJ, Li TM, Ko CH, Cheng CF, Ho TJ, Liu X, Tsang H, Lin TH, Liao CC, Li JP, Huang SM, Lin JC, Lin CC, Liang WM, Lin YJ
Oncotarget 2017 Sep 8;8(38):63528-63550
Oncotarget 2017 Sep 8;8(38):63528-63550
Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer.
Huang XQ, Zhang XF, Xia JH, Chao J, Pan QZ, Zhao JJ, Zhou ZQ, Chen CL, Tang Y, Weng DS, Zhang JH, Xia JC
Chinese journal of cancer 2017 Sep 26;36(1):77
Chinese journal of cancer 2017 Sep 26;36(1):77
RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR.
Li H, Al-Japairai K, Tao Y, Xiang Z
Oncotarget 2017 Sep 22;8(42):72633-72651
Oncotarget 2017 Sep 22;8(42):72633-72651
AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells.
Song Y, Zhang P, Sun Y, Li X, Chen L, Xiao Y, Xing Y
Oncotarget 2017 Sep 15;8(40):67942-67954
Oncotarget 2017 Sep 15;8(40):67942-67954
H(2)O(2) attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor.
Zeng Z, Wang D, Gaur U, Rifang L, Wang H, Zheng W
Oncotarget 2017 Sep 12;8(39):65313-65328
Oncotarget 2017 Sep 12;8(39):65313-65328
Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface.
Li N, Wu HM, Hang F, Zhang YS, Li MJ
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2017 Sep 12;50(11):e6527
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2017 Sep 12;50(11):e6527
Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina.
Chen P, Cai X, Yang Y, Chen Z, Qiu J, Yu N, Tang M, Wang Q, Ge J, Yu K, Zhuang J
Investigative ophthalmology & visual science 2017 Sep 1;58(11):4662-4669
Investigative ophthalmology & visual science 2017 Sep 1;58(11):4662-4669
HMGA2 plays an important role in Cr (VI)-induced autophagy.
Yang F, Zhao L, Mei D, Jiang L, Geng C, Li Q, Yao X, Liu Y, Kong Y, Cao J
International journal of cancer 2017 Sep 1;141(5):986-997
International journal of cancer 2017 Sep 1;141(5):986-997
Melatonin inhibits nucleus pulposus (NP) cell proliferation and extracellular matrix (ECM) remodeling via the melatonin membrane receptors mediated PI3K-Akt pathway.
Li Z, Li X, Chen C, Chan MTV, Wu WKK, Shen J
Journal of pineal research 2017 Oct;63(3)
Journal of pineal research 2017 Oct;63(3)
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
Zhao P, Zhou R, Zhu XY, Liu G, Zhao YP, Ma PS, Wu W, Niu Y, Sun T, Li YX, Yu JQ, Qian ZM
Neurochemical research 2017 Oct;42(10):2798-2813
Neurochemical research 2017 Oct;42(10):2798-2813
Cepharanthine hydrochloride reverses P‑glycoprotein-mediated multidrug resistance in human ovarian carcinoma A2780/Taxol cells by inhibiting the PI3K/Akt signaling pathway.
Huang CZ, Wang YF, Zhang Y, Peng YM, Liu YX, Ma F, Jiang JH, Wang QD
Oncology reports 2017 Oct;38(4):2558-2564
Oncology reports 2017 Oct;38(4):2558-2564
NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.
Wang W, Yi M, Chen S, Li J, Zhang H, Xiong W, Li G, Li X, Xiang B
Journal of cellular physiology 2017 Oct;232(10):2829-2840
Journal of cellular physiology 2017 Oct;232(10):2829-2840
Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells.
Wang Y, He J, Zhang S, Yang Q, Wang B, Liu Z, Wu X
Technology in cancer research & treatment 2017 Oct;16(5):559-569
Technology in cancer research & treatment 2017 Oct;16(5):559-569
Angelicin inhibits liver cancer growth in vitro and in vivo.
Wang F, Li J, Li R, Pan G, Bai M, Huang Q
Molecular medicine reports 2017 Oct;16(4):5441-5449
Molecular medicine reports 2017 Oct;16(4):5441-5449
Human cytomegalovirus miR-US4-5p promotes apoptosis via downregulation of p21-activated kinase 2 in cultured cells.
Shao Y, Qi Y, Huang Y, Liu Z, Ma Y, Guo X, Jiang S, Sun Z, Ruan Q
Molecular medicine reports 2017 Oct;16(4):4171-4178
Molecular medicine reports 2017 Oct;16(4):4171-4178
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
Shen W, Zhu S, Qin H, Zhong M, Wu J, Zhang R, Song H
Molecular medicine reports 2017 Oct;16(4):4054-4060
Molecular medicine reports 2017 Oct;16(4):4054-4060
Expression of the tumor suppressor gene p16, and lymph node metastasis in patients with ovarian cancer.
Wang H, Zheng J, Li Q, Zhou M, Ai D, Zhang H
Oncology letters 2017 Oct;14(4):4689-4693
Oncology letters 2017 Oct;14(4):4689-4693
Silencing of TCTN1 inhibits proliferation, induces cell cycle arrest and apoptosis in human thyroid cancer.
Xu P, Xia X, Yang Z, Tian Y, Di J, Guo M
Experimental and therapeutic medicine 2017 Oct;14(4):3720-3726
Experimental and therapeutic medicine 2017 Oct;14(4):3720-3726
Identification of novel direct protein-protein interactions by irradiating living cells with femtosecond UV laser pulses.
Itri F, Monti DM, Chino M, Vinciguerra R, Altucci C, Lombardi A, Piccoli R, Birolo L, Arciello A
Biochemical and biophysical research communications 2017 Oct 7;492(1):67-73
Biochemical and biophysical research communications 2017 Oct 7;492(1):67-73
Hyperoside alleviates adriamycin-induced podocyte injury via inhibiting mitochondrial fission.
Chen Z, An X, Liu X, Qi J, Ding D, Zhao M, Duan S, Huang Z, Zhang C, Wu L, Zhang B, Zhang A, Yuan Y, Xing C
Oncotarget 2017 Oct 24;8(51):88792-88803
Oncotarget 2017 Oct 24;8(51):88792-88803
LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells.
Yang Y, Ren M, Song C, Li D, Soomro SH, Xiong Y, Zhang H, Fu H
Oncotarget 2017 Oct 13;8(48):84123-84139
Oncotarget 2017 Oct 13;8(48):84123-84139
Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.
Sheng N, Yan L, You W, Tan G, Gong J, Chen H, Yang Y, Hu L, Wang Z
Acta biochimica et biophysica Sinica 2017 Oct 1;49(10):926-934
Acta biochimica et biophysica Sinica 2017 Oct 1;49(10):926-934
The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells.
Hsieh HH, Chen YC, Jhan JR, Lin JJ
Journal of cell science 2017 Oct 1;130(19):3272-3281
Journal of cell science 2017 Oct 1;130(19):3272-3281
Lentivirus-mediated knockdown of M-phase phosphoprotein 8 inhibits proliferation of colon cancer cells.
Liang X, Liu T, Zhang W, Zhang K, Guo S, Liang J
Biotechnology and applied biochemistry 2017 Nov;64(6):911-917
Biotechnology and applied biochemistry 2017 Nov;64(6):911-917
Carbon monoxide-releasing molecule suppresses inflammatory and osteoclastogenic cytokines in nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via the heme oxygenase-1 pathway.
Song L, Li J, Yuan X, Liu W, Chen Z, Guo D, Yang F, Guo Q, Song H
International journal of molecular medicine 2017 Nov;40(5):1591-1601
International journal of molecular medicine 2017 Nov;40(5):1591-1601
The Shape of Vesicle-Containing Organelles Is Critical for Their Functions in Vesicle Endocytosis.
Winters CM, Hong-Brown LQ, Chiang HL
DNA and cell biology 2017 Nov;36(11):909-921
DNA and cell biology 2017 Nov;36(11):909-921
MicroRNA‑214 targets Wnt3a to suppress liver cancer cell proliferation.
Yang Y, Zhao Z, Hou N, Li Y, Wang X, Wu F, Sun R, Han J, Sun H, Song T, Huang C, Shao Y
Molecular medicine reports 2017 Nov;16(5):6920-6927
Molecular medicine reports 2017 Nov;16(5):6920-6927
PHD3 affects gastric cancer progression by negatively regulating HIF1A.
Xia YJ, Jiang XT, Jiang SB, He XJ, Luo JG, Liu ZC, Wang L, Tao HQ, Chen JZ
Molecular medicine reports 2017 Nov;16(5):6882-6889
Molecular medicine reports 2017 Nov;16(5):6882-6889
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
Gao M, Chen T, Wu L, Zhao X, Mao H, Xing C
Molecular medicine reports 2017 Nov;16(5):6208-6213
Molecular medicine reports 2017 Nov;16(5):6208-6213
CD109 expression is upregulated in penile squamous cell carcinoma.
Dong F, Wang J, Xu Y, Cheng Z, Chen X, Wang Y, Liu J
Oncology letters 2017 Nov;14(5):6012-6016
Oncology letters 2017 Nov;14(5):6012-6016
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Li H, Qiu Z, Li F, Wang C
Oncology letters 2017 Nov;14(5):5865-5870
Oncology letters 2017 Nov;14(5):5865-5870
Correlation between miR-19a inhibition and radiosensitivity in SiHa cervical cancer cells.
Wang Y, Wang Y, Zhong W, Gulina K
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2017 Nov-Dec;22(6):1505-1508
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2017 Nov-Dec;22(6):1505-1508
Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport.
Kvainickas A, Jimenez-Orgaz A, Nägele H, Hu Z, Dengjel J, Steinberg F
The Journal of cell biology 2017 Nov 6;216(11):3677-3693
The Journal of cell biology 2017 Nov 6;216(11):3677-3693
Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
Wang G, Lu M, Yao Y, Wang J, Li J
European journal of pharmacology 2017 Nov 5;814:207-215
European journal of pharmacology 2017 Nov 5;814:207-215
Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling.
Huang X, Balmer S, Yang F, Fidalgo M, Li D, Guallar D, Hadjantonakis AK, Wang J
eLife 2017 Nov 23;6
eLife 2017 Nov 23;6
High expression of PDLIM5 facilitates cell tumorigenesis and migration by maintaining AMPK activation in prostate cancer.
Liu X, Chen L, Huang H, Lv JM, Chen M, Qu FJ, Pan XW, Li L, Yin L, Cui XG, Gao Y, Xu DF
Oncotarget 2017 Nov 17;8(58):98117-98134
Oncotarget 2017 Nov 17;8(58):98117-98134
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Song L, Wang Z, Wang Y, Guo D, Yang J, Chen L, Tan N
Molecules (Basel, Switzerland) 2017 Nov 11;22(11)
Molecules (Basel, Switzerland) 2017 Nov 11;22(11)
Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells.
Wang Z, Jin G, Wu Q, Wang R, Li Y
Acta biochimica et biophysica Sinica 2017 Nov 1;49(11):979-988
Acta biochimica et biophysica Sinica 2017 Nov 1;49(11):979-988
p38β Mitogen-Activated Protein Kinase Signaling Mediates Exenatide-Stimulated Microglial β-Endorphin Expression.
Wu HY, Mao XF, Fan H, Wang YX
Molecular pharmacology 2017 May;91(5):451-463
Molecular pharmacology 2017 May;91(5):451-463
Epigenetic Downregulation of Scn3a Expression by Valproate: a Possible Role in Its Anticonvulsant Activity.
Tan NN, Tang HL, Lin GW, Chen YH, Lu P, Li HJ, Gao MM, Zhao QH, Yi YH, Liao WP, Long YS
Molecular neurobiology 2017 May;54(4):2831-2842
Molecular neurobiology 2017 May;54(4):2831-2842
SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells.
Xu CY, Liu SQ, Qin MB, Zhuge CF, Qin L, Qin N, Lai MY, Huang JA
International journal of molecular medicine 2017 May;39(5):1277-1284
International journal of molecular medicine 2017 May;39(5):1277-1284
A long non-coding RNA lncRNA-PE promotes invasion and epithelial-mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway.
Shen Y, Liu S, Yuan H, Ying X, Fu H, Zheng X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317705756
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317705756
Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial-mesenchymal transition.
Wei H, Xu Z, Liu F, Wang F, Wang X, Sun X, Li J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317691684
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317691684
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Khan SH, Zhao D, Shah SZ, Hassan MF, Zhu T, Song Z, Zhou X, Yang L
Cellular and molecular neurobiology 2017 May;37(4):717-728
Cellular and molecular neurobiology 2017 May;37(4):717-728
In vitro study of human mutL homolog 1 hypermethylation in inducing drug resistance of esophageal carcinoma.
Cao Y, Chen Y, Huang Y, Liu Z, Li G
Irish journal of medical science 2017 May;186(2):257-263
Irish journal of medical science 2017 May;186(2):257-263
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
Zhong X, Tian S, Zhang X, Diao X, Dong F, Yang J, Li Z, Sun L, Wang L, He X, Wu G, Hu X, Wang L, Song L, Zhang H, Pan X, Li A, Gao P
EMBO reports 2017 May;18(5):809-825
EMBO reports 2017 May;18(5):809-825
Effects of autophagy and endocytosis on the activity of matrix metalloproteinase‑2 in human renal proximal tubular cells under hypoxia.
Yu W, Wang Z, Li Y, Liu L, Liu J, Ding F, Zhang X, Cheng Z, Chen P
Molecular medicine reports 2017 May;15(5):3225-3230
Molecular medicine reports 2017 May;15(5):3225-3230
Tetramethylpyrazine-mediated regulation of CXCR4 in retinoblastoma is sensitive to cell density.
Wu N, Xu L, Yang Y, Yu N, Zhang Z, Chen P, Zhang J, Tang M, Yuan M, Ge J, Yu K, Zhuang J
Molecular medicine reports 2017 May;15(5):2481-2488
Molecular medicine reports 2017 May;15(5):2481-2488
Downregulation of calbindin 1, a calcium-binding protein, reduces the proliferation of osteosarcoma cells.
Huang Z, Fan G, Wang D
Oncology letters 2017 May;13(5):3727-3733
Oncology letters 2017 May;13(5):3727-3733
miR-195 inhibits cell proliferation via targeting AEG-1 in hepatocellular carcinoma.
Yan JJ, Chang Y, Zhang YN, Lin JS, He XX, Huang HJ
Oncology letters 2017 May;13(5):3118-3126
Oncology letters 2017 May;13(5):3118-3126
Vps15p regulates the distribution of cup-shaped organelles containing the major eisosome protein Pil1p to the extracellular fraction required for endocytosis of extracellular vesicles carrying metabolic enzymes.
Stein K, Winters C, Chiang HL
Biology of the cell 2017 May;109(5):190-209
Biology of the cell 2017 May;109(5):190-209
Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming.
Saunders A, Li D, Faiola F, Huang X, Fidalgo M, Guallar D, Ding J, Yang F, Xu Y, Zhou H, Wang J
Stem cell reports 2017 May 9;8(5):1115-1123
Stem cell reports 2017 May 9;8(5):1115-1123
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Wu G, Yuan M, Shen S, Ma X, Fang J, Zhu L, Sun L, Liu Z, He X, Huang D, Li T, Li C, Wu J, Hu X, Li Z, Song L, Qu K, Zhang H, Gao P
Nature communications 2017 May 5;8:15278
Nature communications 2017 May 5;8:15278
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
Zhou LT, Ye SH, Yang HX, Zhou YT, Zhao QH, Sun WW, Gao MM, Yi YH, Long YS
Neuroscience 2017 May 4;349:64-75
Neuroscience 2017 May 4;349:64-75
α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway.
Zhao Y, Wei A, Zhang H, Chen X, Wang L, Zhang H, Yu X, Yuan Q, Zhang J, Wang S
Oncogenesis 2017 May 29;6(5):e343
Oncogenesis 2017 May 29;6(5):e343
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations.
Zhou X, Sun L, Bracko O, Choi JW, Jia Y, Nana AL, Brady OA, Hernandez JCC, Nishimura N, Seeley WW, Hu F
Nature communications 2017 May 25;8:15277
Nature communications 2017 May 25;8:15277
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F
Journal of virology 2017 May 1;91(9)
Journal of virology 2017 May 1;91(9)
Early growth response 3 inhibits growth of hepatocellular carcinoma cells via upregulation of Fas ligand.
Zhang S, Xia C, Xu C, Liu J, Zhu H, Yang Y, Xu F, Zhao J, Chang Y, Zhao Q
International journal of oncology 2017 Mar;50(3):805-814
International journal of oncology 2017 Mar;50(3):805-814
Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents.
Zhu J, Xu M, Gao M, Zhang Z, Xu Y, Xia T, Liu S
ACS nano 2017 Mar 28;11(3):2637-2651
ACS nano 2017 Mar 28;11(3):2637-2651
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
Fan Y, Li H, Liang X, Xiang Z
Oncotarget 2017 Mar 21;8(12):19934-19946
Oncotarget 2017 Mar 21;8(12):19934-19946
H(2)S regulates endothelial nitric oxide synthase protein stability by promoting microRNA-455-3p expression.
Li XH, Xue WL, Wang MJ, Zhou Y, Zhang CC, Sun C, Zhu L, Liang K, Chen Y, Tao BB, Tan B, Yu B, Zhu YC
Scientific reports 2017 Mar 21;7:44807
Scientific reports 2017 Mar 21;7:44807
miR-935 Promotes Liver Cancer Cell Proliferation and Migration by Targeting SOX7.
Liu X, Li J, Yu Z, Li J, Sun R, Kan Q
Oncology research 2017 Mar 13;25(3):427-435
Oncology research 2017 Mar 13;25(3):427-435
Fibulin-4 reduces extracellular matrix production and suppresses chondrocyte differentiation via DKK1- mediated canonical Wnt/β-catenin signaling.
Shangguan L, Ning G, Luo Z, Zhou Y
International journal of biological macromolecules 2017 Jun;99:293-299
International journal of biological macromolecules 2017 Jun;99:293-299
Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells.
Qian DY, Yan GB, Bai B, Chen Y, Zhang SJ, Yao YC, Xia H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jun;90:492-499
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jun;90:492-499
MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.
Sheng N, Tan G, You W, Chen H, Gong J, Chen D, Zhang H, Wang Z
Cancer medicine 2017 Jun;6(6):1331-1340
Cancer medicine 2017 Jun;6(6):1331-1340
A novel antisense long non-coding RNA SATB2-AS1 overexpresses in osteosarcoma and increases cell proliferation and growth.
Liu SH, Zhu JW, Xu HH, Zhang GQ, Wang Y, Liu YM, Liang JB, Wang YX, Wu Y, Guo QF
Molecular and cellular biochemistry 2017 Jun;430(1-2):47-56
Molecular and cellular biochemistry 2017 Jun;430(1-2):47-56
Long non-coding RNA PVT1 serves as a competing endogenous RNA for miR-186-5p to promote the tumorigenesis and metastasis of hepatocellular carcinoma.
Lan T, Yan X, Li Z, Xu X, Mao Q, Ma W, Hong Z, Chen X, Yuan Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317705338
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317705338
EpCAM and COX‑2 expression are positively correlated in human breast cancer.
Gao S, Sun Y, Liu X, Zhang D, Yang X
Molecular medicine reports 2017 Jun;15(6):3755-3760
Molecular medicine reports 2017 Jun;15(6):3755-3760
Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.
Jiang H, Wang Y, Ai M, Wang H, Duan Z, Wang H, Zhao L, Yu J, Ding Y, Wang S
Cell death & disease 2017 Jun 8;8(6):e2862
Cell death & disease 2017 Jun 8;8(6):e2862
Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.
Jiang H, Guo S, Xiao D, Bian X, Wang J, Wang Y, Zhou H, Cai J, Zheng Z
Oncotarget 2017 Jun 6;8(23):37694-37704
Oncotarget 2017 Jun 6;8(23):37694-37704
3'UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma.
Hua KT, Liu YF, Hsu CL, Cheng TY, Yang CY, Chang JS, Lee WJ, Hsiao M, Juan HF, Chien MH, Yang SF
Scientific reports 2017 Jun 30;7(1):4466
Scientific reports 2017 Jun 30;7(1):4466
The RNA editome of Macaca mulatta and functional characterization of RNA editing in mitochondria.
Ye LQ, Zhao H, Zhou HJ, Ren XD, Liu LL, Otecko NO, Wang ZB, Yang MM, Zeng L, Hu XT, Yao YG, Zhang YP, Wu DD
Science bulletin 2017 Jun 30;62(12):820-830
Science bulletin 2017 Jun 30;62(12):820-830
Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway.
Zhang H, Chen F, He Y, Yi L, Ge C, Shi X, Tang C, Wang D, Wu Y, Nian W
Bioscience reports 2017 Jun 30;37(3)
Bioscience reports 2017 Jun 30;37(3)
PRL-3 promotes telomere deprotection and chromosomal instability.
Lian S, Meng L, Yang Y, Ma T, Xing X, Feng Q, Song Q, Liu C, Tian Z, Qu L, Shou C
Nucleic acids research 2017 Jun 20;45(11):6546-6571
Nucleic acids research 2017 Jun 20;45(11):6546-6571
Gene expression effects of glucocorticoid and mineralocorticoid receptor agonists and antagonists on normal human skeletal muscle.
Chadwick JA, Hauck JS, Gomez-Sanchez CE, Gomez-Sanchez EP, Rafael-Fortney JA
Physiological genomics 2017 Jun 1;49(6):277-286
Physiological genomics 2017 Jun 1;49(6):277-286
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
Li J, Li S, Wang X, Wang H
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cells.
Chen M, Lv JM, Ye JQ, Cui XG, Qu FJ, Chen L, Liu X, Pan XW, Li L, Huang H, Yang QW, Chen J, Wang LH, Gao Y, Xu DF
International journal of oncology 2017 Jul;51(1):39-48
International journal of oncology 2017 Jul;51(1):39-48
Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation.
Zhang T, Hu Y, Wang T, Cai P
International journal of molecular medicine 2017 Jul;40(1):21-30
International journal of molecular medicine 2017 Jul;40(1):21-30
A novel damage mechanism: Contribution of the interaction between necroptosis and ROS to high glucose-induced injury and inflammation in H9c2 cardiac cells.
Liang W, Chen M, Zheng D, He J, Song M, Mo L, Feng J, Lan J
International journal of molecular medicine 2017 Jul;40(1):201-208
International journal of molecular medicine 2017 Jul;40(1):201-208
Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening.
Zhou S, Xiao Y, Zhuang Y, Liu Y, Zhao H, Yang H, Xie C, Zhou F, Zhou Y
Oncology reports 2017 Jul;38(1):515-521
Oncology reports 2017 Jul;38(1):515-521
miR-1247-5p functions as a tumor suppressor in human hepatocellular carcinoma by targeting Wnt3.
Chu Y, Fan W, Guo W, Zhang Y, Wang L, Guo L, Duan X, Wei J, Xu G
Oncology reports 2017 Jul;38(1):343-351
Oncology reports 2017 Jul;38(1):343-351
Porphyromonas gingivalis and its LPS differentially regulate the expression of peptidyl arginine deiminases in human chondrocytes.
Elkaim R, Bugueno-Valdebenito IM, Benkirane-Jessel N, Tenenbaum H
Innate immunity 2017 Jul;23(5):468-475
Innate immunity 2017 Jul;23(5):468-475
Different macrophages equally induce EMT in endometria of adenomyosis and normal.
An M, Li D, Yuan M, Li Q, Zhang L, Wang G
Reproduction (Cambridge, England) 2017 Jul;154(1):79-92
Reproduction (Cambridge, England) 2017 Jul;154(1):79-92
Rho GDP-dissociation inhibitor α is a potential prognostic biomarker and controls telomere regulation in colorectal cancer.
Huang D, Lu W, Zou S, Wang H, Jiang Y, Zhang X, Li P, Songyang Z, Wang L, Wang J, Huang J, Fang L
Cancer science 2017 Jul;108(7):1293-1302
Cancer science 2017 Jul;108(7):1293-1302
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
Yang W, Sun Z, Yang B, Wang Q
International journal of molecular sciences 2017 Jul 31;18(8)
International journal of molecular sciences 2017 Jul 31;18(8)
E3 ubiquitin ligase Nedd4 inhibits AP-1 activity and TNF-α production through targeting p38α for polyubiquitination and subsequent degradation.
Liu Q, Zhang S, Chen G, Zhou H
Scientific reports 2017 Jul 3;7(1):4521
Scientific reports 2017 Jul 3;7(1):4521
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Wang EX, Zou BY, Shi L, Du LY, Zhu YY, Jiang YM, Ma XD, Kang XH, Wang CY, Zhen YH, Sun LD
Life sciences 2017 Jul 1;180:102-113
Life sciences 2017 Jul 1;180:102-113
Highly expressed NRSN2 is related to malignant phenotype in ovarian cancer.
Tang W, Ren A, Xiao H, Sun H, Li B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jan;85:248-255
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jan;85:248-255
Ezrin expression is altered in mice lymphatic metastatic hepatocellular carcinoma and subcellular fractions upon Annexin 7 modulation in-vitro.
Hago AM, Gamallat Y, Mahmoud SA, Huang Y, Zhang J, Mahmoud YK, Wang J, Wei Y, Wang L, Zhou S, Awsh MA, Yabasin IB, Tang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jan;85:209-217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jan;85:209-217
Hepatic expression of transcription factors affecting developmental regulation of UGT1A1 in the Han Chinese population.
Nie YL, He H, Li JF, Meng XG, Yan L, Wang P, Wang SJ, Bi HZ, Zhang LR, Kan QC
European journal of clinical pharmacology 2017 Jan;73(1):29-37
European journal of clinical pharmacology 2017 Jan;73(1):29-37
Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138.
Cai Q, Wang Z, Wang S, Weng M, Zhou D, Li C, Wang J, Chen E, Quan Z
Open biology 2017 Jan;7(1)
Open biology 2017 Jan;7(1)
Beneficial Effects of a CaMKIIα Inhibitor TatCN21 Peptide in Global Cerebral Ischemia.
Ahmed ME, Dong Y, Lu Y, Tucker D, Wang R, Zhang Q
Journal of molecular neuroscience : MN 2017 Jan;61(1):42-51
Journal of molecular neuroscience : MN 2017 Jan;61(1):42-51
Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70.
Zhou Y, Ma J, Zhang J, He L, Gong J, Long C
Oncology reports 2017 Jan;37(1):313-322
Oncology reports 2017 Jan;37(1):313-322
Bif-1 promotes tumor cell migration and metastasis via Cdc42 expression and activity.
Zhang C, Liu F, Chen H, Li N, Luo Z, Guo W, Huang D, Tang S, Wang H, Cheng S, Li Z, Wang H
Clinical & experimental metastasis 2017 Jan;34(1):11-23
Clinical & experimental metastasis 2017 Jan;34(1):11-23
Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy.
Wang Y, Li M, Xu L, Liu J, Wang D, Li Q, Wang L, Li P, Chen S, Liu T
Molecular medicine reports 2017 Jan;15(1):359-365
Molecular medicine reports 2017 Jan;15(1):359-365
Tumor necrosis factor receptor 2 promotes growth of colorectal cancer via the PI3K/AKT signaling pathway.
Zhao T, Li H, Liu Z
Oncology letters 2017 Jan;13(1):342-346
Oncology letters 2017 Jan;13(1):342-346
Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells.
Dai X, Dong M, Yu H, Xie Y, Yu Y, Cao Y, Kong Z, Zhou B, Xu Y, Yang T, Li K
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 26;23:452-461
Medical science monitor : international medical journal of experimental and clinical research 2017 Jan 26;23:452-461
Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes tumorigenesis and metastasis by targeting miR-199a/b-5p in hepatocellular carcinoma.
Lan T, Ma W, Hong Z, Wu L, Chen X, Yuan Y
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):11
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):11
Interaction of macrophages and endometrial cells induces epithelial-mesenchymal transition-like processes in adenomyosis.
An M, Li D, Yuan M, Li Q, Zhang L, Wang G
Biology of reproduction 2017 Jan 1;96(1):46-57
Biology of reproduction 2017 Jan 1;96(1):46-57
Host Cellular Protein TRAPPC6AΔ Interacts with Influenza A Virus M2 Protein and Regulates Viral Propagation by Modulating M2 Trafficking.
Zhu P, Liang L, Shao X, Luo W, Jiang S, Zhao Q, Sun N, Zhao Y, Li J, Wang J, Zhou Y, Zhang J, Wang G, Jiang L, Chen H, Li C
Journal of virology 2017 Jan 1;91(1)
Journal of virology 2017 Jan 1;91(1)
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
ISG15 inhibits cancer cell growth and promotes apoptosis.
Zhou MJ, Chen FZ, Chen HC, Wan XX, Zhou X, Fang Q, Zhang DZ
International journal of molecular medicine 2017 Feb;39(2):446-452
International journal of molecular medicine 2017 Feb;39(2):446-452
The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regeneration.
Li C, Chang L, Chen Z, Liu Z, Wang Y, Ye Q
International journal of molecular medicine 2017 Feb;39(2):347-356
International journal of molecular medicine 2017 Feb;39(2):347-356
Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer.
Zeng T, Zhu L, Liao M, Zhuo W, Yang S, Wu W, Wang D
Medical oncology (Northwood, London, England) 2017 Feb;34(2):27
Medical oncology (Northwood, London, England) 2017 Feb;34(2):27
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
Aras S, Arrabi H, Purandare N, Hüttemann M, Kamholz J, Züchner S, Grossman LI
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
Elevated systemic glutamic acid level in the non-obese diabetic mouse is Idd linked and induces beta cell apoptosis.
Banday VS, Lejon K
Immunology 2017 Feb;150(2):162-171
Immunology 2017 Feb;150(2):162-171
Downregulation of the β1 adrenergic receptor in the myocardium results in insensitivity to metoprolol and reduces blood pressure in spontaneously hypertensive rats.
Huang Y, Liu XL, Wen J, Huang LH, Lu Y, Miao RJ, Liu X, Li Y, Xing XW, Yuan H
Molecular medicine reports 2017 Feb;15(2):703-711
Molecular medicine reports 2017 Feb;15(2):703-711
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a.
Ji J, Zeng XN, Cao LL, Zhang L, Zhao Z, Yang DD, Sun XL
Neuropharmacology 2017 Feb;113(Pt A):396-406
Neuropharmacology 2017 Feb;113(Pt A):396-406
Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts.
Tsai FJ, Ho TJ, Cheng CF, Shiao YT, Chien WK, Chen JH, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin CW, Lin JG, Lan YC, Liu YH, Hung CH, Lin JC, Lin CC, Lai CH, Liang WM, Lin YJ
Oncotarget 2017 Feb 28;8(9):15470-15489
Oncotarget 2017 Feb 28;8(9):15470-15489
Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model.
Wang H, Mo L, Xiao X, An S, Liu X, Ba J, Wu W, Ran P, Yang P, Liu Z
Scientific reports 2017 Feb 27;7:43322
Scientific reports 2017 Feb 27;7:43322
The role of alternative polyadenylation in the antiviral innate immune response.
Jia X, Yuan S, Wang Y, Fu Y, Ge Y, Ge Y, Lan X, Feng Y, Qiu F, Li P, Chen S, Xu A
Nature communications 2017 Feb 24;8:14605
Nature communications 2017 Feb 24;8:14605
UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy.
Hu L, Li X, Liu Q, Xu J, Ge H, Wang Z, Wang H, Wang Z, Shi C, Xu X, Huang J, Lin Z, Pieper RO, Weng C
Oncogene 2017 Feb 23;36(8):1145-1156
Oncogene 2017 Feb 23;36(8):1145-1156
Sensitive Approaches for the Assay of the Global Protein Tyrosine Phosphorylation in Complex Samples Using a Mutated SH2 Domain.
Li Y, Wang Y, Dong M, Zou H, Ye M
Analytical chemistry 2017 Feb 21;89(4):2304-2311
Analytical chemistry 2017 Feb 21;89(4):2304-2311
miR-138-5p suppresses autophagy in pancreatic cancer by targeting SIRT1.
Tian S, Guo X, Yu C, Sun C, Jiang J
Oncotarget 2017 Feb 14;8(7):11071-11082
Oncotarget 2017 Feb 14;8(7):11071-11082
Histone Modifications Regulate the Developmental Expression of Human Hepatic UDP-Glucuronosyltransferase 1A1.
Nie YL, Meng XG, Liu JY, Yan L, Wang P, Bi HZ, Kan QC, Zhang LR
Drug metabolism and disposition: the biological fate of chemicals 2017 Dec;45(12):1372-1378
Drug metabolism and disposition: the biological fate of chemicals 2017 Dec;45(12):1372-1378
Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1.
Zang S, Tang Q, Dong F, Liu H, Li L, Guo F, Pan X, Lin H, Zeng W, Cai Z, Zhong Q, Zang N, Zang L
Oncology reports 2017 Dec;38(6):3583-3591
Oncology reports 2017 Dec;38(6):3583-3591
Hydrogen sulfide ameliorated L-NAME-induced hypertensive heart disease by the Akt/eNOS/NO pathway.
Jin S, Teng X, Xiao L, Xue H, Guo Q, Duan X, Chen Y, Wu Y
Experimental biology and medicine (Maywood, N.J.) 2017 Dec;242(18):1831-1841
Experimental biology and medicine (Maywood, N.J.) 2017 Dec;242(18):1831-1841
Clinical implications of progranulin in gastric cancer and its regulation via a positive feedback loop involving AKT and ERK signaling pathways.
Yang D, Li R, Wang H, Wang J, Han L, Pan L, Li X, Kong Q, Wang G, Su X
Molecular medicine reports 2017 Dec;16(6):9685-9691
Molecular medicine reports 2017 Dec;16(6):9685-9691
P38/ERK MAPK signaling pathways are involved in the regulation of filaggrin and involucrin by IL‑17.
Tan Q, Yang H, Liu E, Wang H
Molecular medicine reports 2017 Dec;16(6):8863-8867
Molecular medicine reports 2017 Dec;16(6):8863-8867
MACC1 facilitates chemoresistance and cancer stem cell‑like properties of colon cancer cells through the PI3K/AKT signaling pathway.
Wang J, Wang W, Cai H, Du B, Zhang L, Ma W, Hu Y, Feng S, Miao G
Molecular medicine reports 2017 Dec;16(6):8747-8754
Molecular medicine reports 2017 Dec;16(6):8747-8754
Baicalin potentiates TRAIL‑induced apoptosis through p38 MAPK activation and intracellular reactive oxygen species production.
Zhang L, Wang X, Wang R, Zheng X, Li N, Li H, Cao X, Zhou B, Lin Y, Yang L
Molecular medicine reports 2017 Dec;16(6):8549-8555
Molecular medicine reports 2017 Dec;16(6):8549-8555
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
Pang X, Li R, Shi D, Pan X, Ma C, Zhang G, Mu C, Chen W
Oncology letters 2017 Dec;14(6):8028-8034
Oncology letters 2017 Dec;14(6):8028-8034
BTBD7 silencing inhibited epithelial- mesenchymal transition (EMT) via regulating Slug expression in human salivary adenoid cystic carcinoma.
Yang L, Wang T, Zhang J, Wang X
Cancer biomarkers : section A of Disease markers 2017 Dec 6;20(4):461-468
Cancer biomarkers : section A of Disease markers 2017 Dec 6;20(4):461-468
Chlamydia trachomatis plasmid-encoded protein pORF5 protects mitochondrial function by inducing mitophagy and increasing HMGB1 expression.
Lei W, Li Q, Su S, Bu J, Huang Q, Li Z
Pathogens and disease 2017 Dec 29;75(9)
Pathogens and disease 2017 Dec 29;75(9)
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
Zuo LL, Zhang J, Liu LZ, Zhou Q, Du SJ, Xin SY, Ning ZP, Yang J, Yu HB, Yue WX, Wang J, Zhu FX, Li GY, Lu JH
Oncogenesis 2017 Dec 22;6(12):402
Oncogenesis 2017 Dec 22;6(12):402
High-intensity interval versus moderate-intensity continuous training: Superior metabolic benefits in diet-induced obesity mice.
Wang N, Liu Y, Ma Y, Wen D
Life sciences 2017 Dec 15;191:122-131
Life sciences 2017 Dec 15;191:122-131
Phenotype and Functional Analyses in a Transgenic Mouse Model of Left Ventricular Noncompaction Caused by a DTNA Mutation.
Cao Q, Shen Y, Liu X, Yu X, Yuan P, Wan R, Liu X, Peng X, He W, Pu J, Hong K
International heart journal 2017 Dec 12;58(6):939-947
International heart journal 2017 Dec 12;58(6):939-947
Effects of high-intensity focused ultrasound on cisplatin-resistant human lung adenocarcinoma in vitro and in vivo.
Zhang T, Chen L, Zhang S, Xu Y, Fan Y, Zhang L
Acta biochimica et biophysica Sinica 2017 Dec 1;49(12):1092-1098
Acta biochimica et biophysica Sinica 2017 Dec 1;49(12):1092-1098
6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon α/β by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells.
Wonganan O, He YJ, Shen XF, Wongkrajang K, Suksamrarn A, Zhang GL, Wang F
Toxicology and applied pharmacology 2017 Dec 1;336:31-39
Toxicology and applied pharmacology 2017 Dec 1;336:31-39
Proteomics of acute heart failure in a rat post-myocardial infarction model.
Guo Y, Cui L, Jiang S, Zhang A, Jiang S
Molecular medicine reports 2017 Aug;16(2):1946-1956
Molecular medicine reports 2017 Aug;16(2):1946-1956
Clinical implications of vasohibin-1 in esophageal carcinoma cells: Inhibition of cell growth and migration.
Ma D, Li J, Wang J, Sun Z, Wang K
Molecular medicine reports 2017 Aug;16(2):1479-1485
Molecular medicine reports 2017 Aug;16(2):1479-1485
Protective role of 17β-estradiol on tumor necrosis factor-α-induced apoptosis in human nucleus pulposus cells.
Liu H, Yang SD, Xu Y, Ning SH, Wang T, Yang DL, Ding WY
Molecular medicine reports 2017 Aug;16(2):1093-1100
Molecular medicine reports 2017 Aug;16(2):1093-1100
CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation.
Tang T, Lang X, Xu C, Wang X, Gong T, Yang Y, Cui J, Bai L, Wang J, Jiang W, Zhou R
Nature communications 2017 Aug 4;8(1):202
Nature communications 2017 Aug 4;8(1):202
The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis.
Wang G, Zhou P, Chen X, Zhao L, Tan J, Yang Y, Fang Y, Zhou J
Cancer biology & therapy 2017 Aug 3;18(8):584-595
Cancer biology & therapy 2017 Aug 3;18(8):584-595
LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells.
Shi X, Zhang H, Wang M, Xu X, Zhao Y, He R, Zhang M, Zhou M, Li X, Peng F, Shi C, Shen M, Wang X, Guo X, Qin R
Oncotarget 2017 Aug 29;8(35):58394-58404
Oncotarget 2017 Aug 29;8(35):58394-58404
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
Epigallocatechin-3-gallate inhibits H(2)O(2)-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Yan X, Li Y, Yu H, Wang W, Wu C, Yang Y, Hu Y, Shi X, Li J
Scientific reports 2017 Aug 10;7(1):7774
Scientific reports 2017 Aug 10;7(1):7774
Ursolic acid improves podocyte injury caused by high glucose.
Xu L, Fan Q, Wang X, Li L, Lu X, Yue Y, Cao X, Liu J, Zhao X, Wang L
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2017 Aug 1;32(8):1285-1293
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2017 Aug 1;32(8):1285-1293
Systematic Characterization of Autophagy in Gestational Diabetes Mellitus.
Ji L, Chen Z, Xu Y, Xiong G, Liu R, Wu C, Hu H, Wang L
Endocrinology 2017 Aug 1;158(8):2522-2532
Endocrinology 2017 Aug 1;158(8):2522-2532
Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.
Jian C, Xu F, Hou T, Sun T, Li J, Cheng H, Wang X
Journal of cell science 2017 Aug 1;130(15):2620-2630
Journal of cell science 2017 Aug 1;130(15):2620-2630
Downregulation of B-myb promotes senescence via the ROS-mediated p53/p21 pathway, in vascular endothelial cells.
Zhou Z, Yin Y, Chang Q, Sun G, Lin J, Dai Y
Cell proliferation 2017 Apr;50(2)
Cell proliferation 2017 Apr;50(2)
ICT1 knockdown inhibits breast cancer cell growth via induction of cell cycle arrest and apoptosis.
Wang C, Liang C, Feng W, Xia X, Chen F, Qiao E, Zhang X, Chen D, Ling Z, Yang H
International journal of molecular medicine 2017 Apr;39(4):1037-1045
International journal of molecular medicine 2017 Apr;39(4):1037-1045
Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer in vitro.
Wang Z, Kang J, Deng X, Guo B, Wu B, Fan Y
Oncology reports 2017 Apr;37(4):2147-2152
Oncology reports 2017 Apr;37(4):2147-2152
Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism.
Wang C, Wang H, Zhang Y, Guo W, Long C, Wang J, Liu L, Sun X
Oncology reports 2017 Apr;37(4):2109-2120
Oncology reports 2017 Apr;37(4):2109-2120
G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways.
Wang Y, Xiao H, Wu H, Yao C, He H, Wang C, Li W
Oncology reports 2017 Apr;37(4):1998-2006
Oncology reports 2017 Apr;37(4):1998-2006
FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide.
Ma J, Li J, Yao X, Lin S, Gu Y, Xu J, Deng Z, Ma W, Zhang H
Oncology reports 2017 Apr;37(4):1935-1942
Oncology reports 2017 Apr;37(4):1935-1942
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Dendrobium nobile Lindl alkaloid, a novel autophagy inducer, protects against axonal degeneration induced by Aβ(25-35) in hippocampus neurons in vitro.
Li LS, Lu YL, Nie J, Xu YY, Zhang W, Yang WJ, Gong QH, Lu YF, Lu Y, Shi JS
CNS neuroscience & therapeutics 2017 Apr;23(4):329-340
CNS neuroscience & therapeutics 2017 Apr;23(4):329-340
Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions.
Shen Y, Liu S, Fan J, Jin Y, Tian B, Zheng X, Fu H
EMBO reports 2017 Apr;18(4):536-548
EMBO reports 2017 Apr;18(4):536-548
Lentivirus-mediated RNA interference of tripartite motif 68 inhibits the proliferation of colorectal cancer cell lines SW1116 and HCT116 in vitro.
Tan Z, Liu X, Yu E, Wang H, Tang L, Wang H, Fu C
Oncology letters 2017 Apr;13(4):2649-2655
Oncology letters 2017 Apr;13(4):2649-2655
Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways.
Zhang C, Li C, Chen S, Li Z, Jia X, Wang K, Bao J, Liang Y, Wang X, Chen M, Li P, Su H, Wan JB, Lee SMY, Liu K, He C
Redox biology 2017 Apr;11:1-11
Redox biology 2017 Apr;11:1-11
Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.
Feng L, Zhang J, Zhu N, Ding Q, Zhang X, Yu J, Qiang W, Zhang Z, Ma Y, Huang D, Shen Y, Fang S, Yu Y, Wang H, Shen Y
Autophagy 2017 Apr 3;13(4):686-702
Autophagy 2017 Apr 3;13(4):686-702
MicroRNA-26a targets MAPK6 to inhibit smooth muscle cell proliferation and vein graft neointimal hyperplasia.
Tan J, Yang L, Liu C, Yan Z
Scientific reports 2017 Apr 21;7:46602
Scientific reports 2017 Apr 21;7:46602
Paper/PMMA Hybrid 3D Cell Culture Microfluidic Platform for the Study of Cellular Crosstalk.
Lei KF, Chang CH, Chen MJ
ACS applied materials & interfaces 2017 Apr 19;9(15):13092-13101
ACS applied materials & interfaces 2017 Apr 19;9(15):13092-13101
MicroRNA-490 inhibits tumorigenesis and progression in breast cancer.
Zhao L, Zheng XY
OncoTargets and therapy 2016;9:4505-16
OncoTargets and therapy 2016;9:4505-16
High expression of Y-box-binding protein 1 correlates with poor prognosis and early recurrence in patients with small invasive lung adenocarcinoma.
Zhao S, Guo W, Li J, Yu W, Guo T, Deng W, Gu C
OncoTargets and therapy 2016;9:2683-92
OncoTargets and therapy 2016;9:2683-92
Bone marrow derived mesenchymal stem cells alleviated brain injury via down-regulation of interleukin-1β in focal cerebral ischemic rats.
Zhao Y, Wang X, Dong P, Xu Q, Ma Z, Mu Q, Sun X, Jiang Z, Wang X
American journal of translational research 2016;8(3):1541-50
American journal of translational research 2016;8(3):1541-50
MicroRNA-541 promotes the proliferation of vascular smooth muscle cells by targeting IRF7.
Yang F, Xu Z, Duan S, Luo M
American journal of translational research 2016;8(2):506-15
American journal of translational research 2016;8(2):506-15
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
Wang H, Hu W, Liang Z, Zeng L, Li J, Yan H, Yang P, Liu Z, Wang L
American journal of translational research 2016;8(12):5320-5329
American journal of translational research 2016;8(12):5320-5329
Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats.
Terrando N, Yang T, Wang X, Fang J, Cao M, Andersson U, Erlandsson HH, Ouyang W, Tong J
Frontiers in immunology 2016;7:441
Frontiers in immunology 2016;7:441
Madagascine Induces Vasodilatation via Activation of AMPK.
Chen D, Lv B, Kobayashi S, Xiong Y, Sun P, Lin Y, Genovese S, Epifano F, Hou S, Tang F, Ji Y, Yu D
Frontiers in pharmacology 2016;7:435
Frontiers in pharmacology 2016;7:435
DEC2 suppresses tumor proliferation and metastasis by regulating ERK/NF-κB pathway in gastric cancer.
Li P, Jia YF, Ma XL, Zheng Y, Kong Y, Zhang Y, Zong S, Chen ZT, Wang YS
American journal of cancer research 2016;6(8):1741-57
American journal of cancer research 2016;6(8):1741-57
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Wang D, Wang D, Wang N, Long Z, Ren X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Combined effect of 17β-estradiol and resveratrol against apoptosis induced by interleukin-1β in rat nucleus pulposus cells via PI3K/Akt/caspase-3 pathway.
Yang SD, Ma L, Yang DL, Ding WY
PeerJ 2016;4:e1640
PeerJ 2016;4:e1640
The Downregulation of MicroRNA-10b and its Role in Cervical Cancer.
Zou D, Zhou Q, Wang D, Guan L, Yuan L, Li S
Oncology research 2016;24(2):99-108
Oncology research 2016;24(2):99-108
Identification of Centella asiatica's Effective Ingredients for Inducing the Neuronal Differentiation.
Jiang H, Zheng G, Lv J, Chen H, Lin J, Li Y, Fan G, Ding X
Evidence-based complementary and alternative medicine : eCAM 2016;2016:9634750
Evidence-based complementary and alternative medicine : eCAM 2016;2016:9634750
Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy.
Yan N, Wen L, Peng R, Li H, Liu H, Peng H, Sun Y, Wu T, Chen L, Duan Q, Sun Y, Zhou Q, Wei L, Zhang Z
Journal of diabetes research 2016;2016:8738760
Journal of diabetes research 2016;2016:8738760
High Expression of PTGR1 Promotes NSCLC Cell Growth via Positive Regulation of Cyclin-Dependent Protein Kinase Complex.
Huang X, Zhou W, Zhang Y, Liu Y
BioMed research international 2016;2016:5230642
BioMed research international 2016;2016:5230642
Knockdown of USP39 by lentivirus-mediated RNA interference suppresses the growth of oral squamous cell carcinoma.
Li KY, Zhang J, Jiang LC, Zhang B, Xia CP, Xu K, Chen HY, Yang QZ, Liu SW, Zhu H
Cancer biomarkers : section A of Disease markers 2016;16(1):137-144
Cancer biomarkers : section A of Disease markers 2016;16(1):137-144
Expression of microtubule-associated protein TPX2 in human gastric carcinoma and its prognostic significance.
Shao C, Duan C, Wang J, Luan S, Gao Y, Jin D, Wang D, Li Y, Xu L
Cancer cell international 2016;16:79
Cancer cell international 2016;16:79
S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory Hepcidin and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway.
Wang M, Tang W, Xin H, Zhu YZ
PloS one 2016;11(9):e0163289
PloS one 2016;11(9):e0163289
Renal Denervation Suppresses the Inducibility of Atrial Fibrillation in a Rabbit Model for Atrial Fibrosis.
Wei Y, Xu J, Zhou G, Chen S, Ouyang P, Liu S
PloS one 2016;11(8):e0160634
PloS one 2016;11(8):e0160634
Suppression of USP18 Potentiates the Anti-HBV Activity of Interferon Alpha in HepG2.2.15 Cells via JAK/STAT Signaling.
Li L, Lei QS, Zhang SJ, Kong LN, Qin B
PloS one 2016;11(5):e0156496
PloS one 2016;11(5):e0156496
Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme.
Chen PT, Chen CL, Lin LT, Lo CH, Hu CJ, Chen RP, Wang SS
PloS one 2016;11(4):e0153360
PloS one 2016;11(4):e0153360
The Expression of Bone Morphogenetic Protein 2 and Matrix Metalloproteinase 2 through Retinoic Acid Receptor Beta Induced by All-Trans Retinoic Acid in Cultured ARPE-19 Cells.
Gao Z, Huo L, Cui D, Yang X, Zeng J
PloS one 2016;11(3):e0150831
PloS one 2016;11(3):e0150831
Estrogen-related receptor (ERR) γ protects against puromycin aminonucleoside-induced podocyte apoptosis by targeting PI3K/Akt signaling.
Gong W, Yu J, Wang Q, Li S, Song J, Jia Z, Huang S, Zhang A
The international journal of biochemistry & cell biology 2016 Sep;78:75-86
The international journal of biochemistry & cell biology 2016 Sep;78:75-86
Extracellular pH regulates autophagy via the AMPK-ULK1 pathway in rat cardiomyocytes.
Zhao L, Cui L, Jiang X, Zhang J, Zhu M, Jia J, Zhang Q, Zhang J, Zhang D, Huang Y
FEBS letters 2016 Sep;590(18):3202-12
FEBS letters 2016 Sep;590(18):3202-12
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Huang D, Wang S, Wang A, Chen X, Zhang H
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Wei WJ, Shen CT, Song HJ, Qiu ZL, Luo QY
Oncology reports 2016 Sep;36(3):1576-84
Oncology reports 2016 Sep;36(3):1576-84
MYO6 knockdown inhibits the growth and induces the apoptosis of prostate cancer cells by decreasing the phosphorylation of ERK1/2 and PRAS40.
Wang D, Zhu L, Liao M, Zeng T, Zhuo W, Yang S, Wu W
Oncology reports 2016 Sep;36(3):1285-92
Oncology reports 2016 Sep;36(3):1285-92
Aberrant adenosine A2A receptor signaling contributes to neurodegeneration and cognitive impairments in a mouse model of synucleinopathy.
Hu Q, Ren X, Liu Y, Li Z, Zhang L, Chen X, He C, Chen JF
Experimental neurology 2016 Sep;283(Pt A):213-23
Experimental neurology 2016 Sep;283(Pt A):213-23
The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia.
Shen C, Chen MT, Zhang XH, Yin XL, Ning HM, Su R, Lin HS, Song L, Wang F, Ma YN, Zhao HL, Yu J, Zhang JW
PLoS genetics 2016 Sep;12(9):e1006259
PLoS genetics 2016 Sep;12(9):e1006259
miR-19a/b modulates lung cancer cells metastasis through suppression of MXD1 expression.
Hu W, Jin P, Ding C, Liu W
Oncology letters 2016 Sep;12(3):1901-1905
Oncology letters 2016 Sep;12(3):1901-1905
Roles and regulation of autophagy and apoptosis in the remodelling of the lepidopteran midgut epithelium during metamorphosis.
Romanelli D, Casartelli M, Cappellozza S, de Eguileor M, Tettamanti G
Scientific reports 2016 Sep 9;6:32939
Scientific reports 2016 Sep 9;6:32939
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, Du Z, Lin H, Duan Y, Du G
Oncotarget 2016 Sep 20;7(38):61093-61106
Oncotarget 2016 Sep 20;7(38):61093-61106
PDGF-D/PDGFRβ promotes tongue squamous carcinoma cell (TSCC) progression via activating p38/AKT/ERK/EMT signal pathway.
Zhang H, Sun JD, Yan LJ, Zhao XP
Biochemical and biophysical research communications 2016 Sep 16;478(2):845-51
Biochemical and biophysical research communications 2016 Sep 16;478(2):845-51
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
Cai X, Yang Y, Chen P, Ye Y, Liu X, Wu K, Yu M
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
Zfp281 Coordinates Opposing Functions of Tet1 and Tet2 in Pluripotent States.
Fidalgo M, Huang X, Guallar D, Sanchez-Priego C, Valdes VJ, Saunders A, Ding J, Wu WS, Clavel C, Wang J
Cell stem cell 2016 Sep 1;19(3):355-69
Cell stem cell 2016 Sep 1;19(3):355-69
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Guo YJ, Dong SY, Cui XX, Feng Y, Liu T, Yin M, Kuo SH, Tan EK, Zhao WJ, Wu YC
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis.
Zhang Y, Cheng Z, Wang C, Ma H, Meng W, Zhao Q
Neurochemical research 2016 Oct;41(10):2549-2558
Neurochemical research 2016 Oct;41(10):2549-2558
The Central Analgesic Mechanism of YM-58483 in Attenuating Neuropathic Pain in Rats.
Qi Z, Wang Y, Zhou H, Liang N, Yang L, Liu L, Zhang W
Cellular and molecular neurobiology 2016 Oct;36(7):1035-43
Cellular and molecular neurobiology 2016 Oct;36(7):1035-43
miR-145 suppresses colorectal cancer cell migration and invasion by targeting an ETS-related gene.
Li S, Wu X, Xu Y, Wu S, Li Z, Chen R, Huang N, Zhu Z, Xu X
Oncology reports 2016 Oct;36(4):1917-26
Oncology reports 2016 Oct;36(4):1917-26
The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.
Port SA, Mendes A, Valkova C, Spillner C, Fahrenkrog B, Kaether C, Kehlenbach RH
The Journal of biological chemistry 2016 Oct 28;291(44):23068-23083
The Journal of biological chemistry 2016 Oct 28;291(44):23068-23083
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.
Zhang L, Wang G, Chen S, Ding J, Ju S, Cao H, Tian H
World journal of surgical oncology 2016 Oct 19;14(1):267
World journal of surgical oncology 2016 Oct 19;14(1):267
Overexpression of pro-gastrin releasing peptide promotes the cell proliferation and progression in small cell lung cancer.
Gong Z, Lu R, Xie S, Jiang M, Liu K, Xiao R, Shen J, Wang Y, Guo L
Biochemical and biophysical research communications 2016 Oct 14;479(2):312-318
Biochemical and biophysical research communications 2016 Oct 14;479(2):312-318
Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2.
Miao W, Wu X, Wang K, Wang W, Wang Y, Li Z, Liu J, Li L, Peng L
International journal of molecular sciences 2016 Oct 10;17(10)
International journal of molecular sciences 2016 Oct 10;17(10)
Polysaccharides from Pleurotus ostreatus alleviate cognitive impairment in a rat model of Alzheimer's disease.
Zhang Y, Yang X, Jin G, Yang X, Zhang Y
International journal of biological macromolecules 2016 Nov;92:935-941
International journal of biological macromolecules 2016 Nov;92:935-941
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
Xu D, Wang H, Zheng W, Gao Y, Wang M, Zhang Y, Gao Q
International journal of biological macromolecules 2016 Nov;92:30-36
International journal of biological macromolecules 2016 Nov;92:30-36
Knockdown of Myosin 6 inhibits proliferation of oral squamous cell carcinoma cells.
Zhang X, Huang Z, Hu Y, Liu L
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016 Nov;45(10):740-745
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016 Nov;45(10):740-745
Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.
Lin Z, Xiong L, Lin Q
Molecular and cellular biochemistry 2016 Nov;422(1-2):97-107
Molecular and cellular biochemistry 2016 Nov;422(1-2):97-107
Abnormal Expression of FBXL20 in Refractory Epilepsy Patients and a Pilocarpine-Induced Rat Model.
Fu P, Wen Y, Xiong Y, Zhang Y, Zhang H, Xie Y, Shi Q
Neurochemical research 2016 Nov;41(11):3020-3031
Neurochemical research 2016 Nov;41(11):3020-3031
Geldanamycin, an inhibitor of Hsp90, increases paclitaxel-mediated toxicity in ovarian cancer cells through sustained activation of the p38/H2AX axis.
Mo Q, Zhang Y, Jin X, Gao Y, Wu Y, Hao X, Gao Q, Chen P
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Nov;37(11):14745-14755
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Nov;37(11):14745-14755
Aliskiren targets multiple systems to alleviate cancer cachexia.
Wang C, Guo D, Wang Q, You S, Qiao Z, Liu Y, Dai H, Tang H
Oncology reports 2016 Nov;36(5):3014-3022
Oncology reports 2016 Nov;36(5):3014-3022
An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice.
Xu Y, Liu J, Hua L, Xiao Y, Tian Y, Guo S, Zhang X, He C, Wang L, Yu Y
Human & experimental toxicology 2016 Nov;35(11):1161-1172
Human & experimental toxicology 2016 Nov;35(11):1161-1172
A combined modality of carboplatin and photodynamic therapy suppresses epithelial-mesenchymal transition and matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in HEp-2 human laryngeal cancer cells via ROS-mediated inhibition of MEK/ERK signalling pathway.
Mao W, Sun Y, Zhang H, Cao L, Wang J, He P
Lasers in medical science 2016 Nov;31(8):1697-1705
Lasers in medical science 2016 Nov;31(8):1697-1705
Induction of Amnion Epithelial Apoptosis by Cortisol via tPA/Plasmin System.
Wang W, Liu C, Sun K
Endocrinology 2016 Nov;157(11):4487-4498
Endocrinology 2016 Nov;157(11):4487-4498
Cardioprotective potential of Dendrobium officinale Kimura et Migo against myocardial ischemia in mice.
Dou MM, Zhang ZH, Li ZB, Zhang J, Zhao XY
Molecular medicine reports 2016 Nov;14(5):4407-4414
Molecular medicine reports 2016 Nov;14(5):4407-4414
miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1.
Gao HX, Yan L, Li C, Zhao LM, Liu W
Molecular medicine reports 2016 Nov;14(5):4135-4143
Molecular medicine reports 2016 Nov;14(5):4135-4143
S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics.
Módis K, Ju Y, Ahmad A, Untereiner AA, Altaany Z, Wu L, Szabo C, Wang R
Pharmacological research 2016 Nov;113(Pt A):116-124
Pharmacological research 2016 Nov;113(Pt A):116-124
Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling.
Xu C, Zhang Y, Wang Q, Xu Z, Jiang J, Gao Y, Gao M, Kang J, Wu M, Xiong J, Ji K, Yuan W, Wang Y, Liu H
Nature communications 2016 Nov 4;7:13287
Nature communications 2016 Nov 4;7:13287
The effect of Liuwei Dihuang decoction on PI3K/Akt signaling pathway in liver of type 2 diabetes mellitus (T2DM) rats with insulin resistance.
Dai B, Wu Q, Zeng C, Zhang J, Cao L, Xiao Z, Yang M
Journal of ethnopharmacology 2016 Nov 4;192:382-389
Journal of ethnopharmacology 2016 Nov 4;192:382-389
Neratinib induces ErbB2 ubiquitylation and endocytic degradation via HSP90 dissociation in breast cancer cells.
Zhang Y, Zhang J, Liu C, Du S, Feng L, Luan X, Zhang Y, Shi Y, Wang T, Wu Y, Cheng W, Meng S, Li M, Liu H
Cancer letters 2016 Nov 28;382(2):176-185
Cancer letters 2016 Nov 28;382(2):176-185
Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye.
Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH
Developmental biology 2016 Nov 15;419(2):336-347
Developmental biology 2016 Nov 15;419(2):336-347
MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration.
Mizbani A, Luca E, Rushing EJ, Krützfeldt J
Development (Cambridge, England) 2016 Nov 15;143(22):4137-4148
Development (Cambridge, England) 2016 Nov 15;143(22):4137-4148
Leukemia inhibitory factor promote trophoblast invasion via urokinase-type plasminogen activator receptor in preeclampsia.
Zheng Q, Dai K, Cui X, Yu M, Yang X, Yan B, Liu S, Yan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:102-108
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:102-108
shRNA-mediated RPS15A silencing inhibits U937 acute myeloid leukemia cell proliferation and enhances apoptosis.
Li G, Zhang L, Liu J, Xiao T, Liu G, Wang J, Hou M
Molecular medicine reports 2016 May;13(5):4400-6
Molecular medicine reports 2016 May;13(5):4400-6
MicroRNA-335-5p inhibits osteoblast apoptosis induced by high glucose.
Li J, Feng Z, Chen L, Wang X, Deng H
Molecular medicine reports 2016 May;13(5):4108-12
Molecular medicine reports 2016 May;13(5):4108-12
Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells.
Zeng L, Cai C, Li S, Wang W, Li Y, Chen J, Zhu X, Zeng YA
PLoS genetics 2016 May;12(5):e1006055
PLoS genetics 2016 May;12(5):e1006055
QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis.
Li F, Yi P, Pi J, Li L, Hui J, Wang F, Liang A, Yu J
Oncotarget 2016 May 31;7(22):32821-34
Oncotarget 2016 May 31;7(22):32821-34
Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device.
Yu T, Guo Z, Fan H, Song J, Liu Y, Gao Z, Wang Q
Oncotarget 2016 May 3;7(18):25593-603
Oncotarget 2016 May 3;7(18):25593-603
The p38 MAPK inhibitor BIRB796 enhances the antitumor effects of VX680 in cervical cancer.
Jin X, Mo Q, Zhang Y, Gao Y, Wu Y, Li J, Hao X, Ma D, Gao Q, Chen P
Cancer biology & therapy 2016 May 3;17(5):566-76
Cancer biology & therapy 2016 May 3;17(5):566-76
Nuclear accumulation of Yes-Associated Protein (YAP) maintains the survival of doxorubicin-induced senescent cells by promoting survivin expression.
Ma K, Xu Q, Wang S, Zhang W, Liu M, Liang S, Zhu H, Xu N
Cancer letters 2016 May 28;375(1):84-91
Cancer letters 2016 May 28;375(1):84-91
miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma.
Rang Z, Yang G, Wang YW, Cui F
Biochemical and biophysical research communications 2016 May 27;474(2):315-320
Biochemical and biophysical research communications 2016 May 27;474(2):315-320
Knockdown of prostaglandin reductase 1 (PTGR1) suppresses prostate cancer cell proliferation by inducing cell cycle arrest and apoptosis.
Xue L, Zhu Z, Wang Z, Li H, Zhang P, Wang Z, Chen Q, Chen H, Chong T
Bioscience trends 2016 May 23;10(2):133-9
Bioscience trends 2016 May 23;10(2):133-9
Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway.
Zhanfeng N, Chengquan W, Hechun X, Jun W, Lijian Z, Dede M, Wenbin L, Lei Y
Oncotarget 2016 May 10;7(19):27350-62
Oncotarget 2016 May 10;7(19):27350-62
Downregulation of hepatic betaine:homocysteine methyltransferase (BHMT) expression in taurine-deficient mice is reversed by taurine supplementation in vivo.
Jurkowska H, Niewiadomski J, Hirschberger LL, Roman HB, Mazor KM, Liu X, Locasale JW, Park E, Stipanuk MH
Amino acids 2016 Mar;48(3):665-676
Amino acids 2016 Mar;48(3):665-676
ATP-sensitive K⁺ channels contribute to the protective effects of exogenous hydrogen sulfide against high glucose-induced injury in H9c2 cardiac cells.
Liang W, Chen J, Mo L, Ke X, Zhang W, Zheng D, Pan W, Wu S, Feng J, Song M, Liao X
International journal of molecular medicine 2016 Mar;37(3):763-72
International journal of molecular medicine 2016 Mar;37(3):763-72
Myosin VI contributes to malignant proliferation of human glioma cells.
Xu R, Fang XH, Zhong P
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2016 Mar;20(2):139-45
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2016 Mar;20(2):139-45
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D
Nature immunology 2016 Mar;17(3):241-9
Nature immunology 2016 Mar;17(3):241-9
Identification and comparative analysis of the oriental river prawn (Macrobrachium nipponense) microRNA expression profile during hypoxia using a deep sequencing approach.
Sun S, Fu H, Ge X, Zhu J, Gu Z, Xuan F
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2016 Mar;17:41-7
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2016 Mar;17:41-7
Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy.
Chang L, Huang J, Wang K, Li J, Yan R, Zhu L, Ye J, Wu X, Zhuang S, Li D, Zhang G
BMC cancer 2016 Mar 7;16:190
BMC cancer 2016 Mar 7;16:190
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Bai Y, Shang Q, Zhao H, Pan Z, Guo C, Zhang L, Wang Q
Cell death & disease 2016 Mar 31;7(3):e2169
Cell death & disease 2016 Mar 31;7(3):e2169
Inhibition of lysyl oxidase by prostaglandin E2 via EP2/EP4 receptors in human amnion fibroblasts: Implications for parturition.
Liu C, Zhu P, Wang W, Li W, Shu Q, Chen ZJ, Myatt L, Sun K
Molecular and cellular endocrinology 2016 Mar 15;424:118-27
Molecular and cellular endocrinology 2016 Mar 15;424:118-27
Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells.
Song H, Yoon SP, Kim J
Anatomy & cell biology 2016 Jun;49(2):79-87
Anatomy & cell biology 2016 Jun;49(2):79-87
EIF3D silencing suppresses renal cell carcinoma tumorigenesis via inducing G2/M arrest through downregulation of Cyclin B1/CDK1 signaling.
Pan XW, Chen L, Hong Y, Xu DF, Liu X, Li L, Huang Y, Cui LM, Gan SS, Yang QW, Huang H, Qu FJ, Ye JQ, Wang LH, Cui XG
International journal of oncology 2016 Jun;48(6):2580-90
International journal of oncology 2016 Jun;48(6):2580-90
Human cytomegalovirus-encoded miR-US4-1 promotes cell apoptosis and benefits discharge of infectious virus particles by targeting QARS.
Shao Y, Qi Y, Huang Y, Liu Z, Ma Y, Guo X, Jiang S, Sun Z, Ruan Q
Journal of biosciences 2016 Jun;41(2):183-92
Journal of biosciences 2016 Jun;41(2):183-92
High expression of DDX20 enhances the proliferation and metastatic potential of prostate cancer cells through the NF-κB pathway.
Chen W, Zhou P, Li X
International journal of molecular medicine 2016 Jun;37(6):1551-7
International journal of molecular medicine 2016 Jun;37(6):1551-7
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Yin J, Lu Z, Wang F, Jiang Z, Lu L, Miao N, Wang N
Journal of cellular and molecular medicine 2016 Jun;20(6):1106-17
Journal of cellular and molecular medicine 2016 Jun;20(6):1106-17
Lentivirus-mediated silencing of MPHOSPH8 inhibits MTC proliferation and enhances apoptosis.
Li P, Yang W, Shen B, Li H, Yan J
Oncology letters 2016 Jun;11(6):4117-4122
Oncology letters 2016 Jun;11(6):4117-4122
Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures.
Li M, Zhang ND, Wang Y, Han T, Jiang YP, Rahman K, Qin LP, Xin HL, Zhang QY
Journal of ethnopharmacology 2016 Jun 5;185:120-31
Journal of ethnopharmacology 2016 Jun 5;185:120-31
Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma.
Lin KY, Ye H, Han BW, Wang WT, Wei PP, He B, Li XJ, Chen YQ
Oncogene 2016 Jun 30;35(26):3376-86
Oncogene 2016 Jun 30;35(26):3376-86
HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer.
Li A, Liu Z, Li M, Zhou S, Xu Y, Xiao Y, Yang W
Oncotarget 2016 Jun 21;7(25):37966-37978
Oncotarget 2016 Jun 21;7(25):37966-37978
The expression and prognostic value of protein tyrosine kinase 6 in early-stage cervical squamous cell cancer.
Wang XJ, Xiong Y, Ma ZB, Xia JC, Li YF
Chinese journal of cancer 2016 Jun 16;35(1):54
Chinese journal of cancer 2016 Jun 16;35(1):54
Autophagy maintains ubiquitination-proteasomal degradation of Sirt3 to limit oxidative stress in K562 leukemia cells.
Fang Y, Wang J, Xu L, Cao Y, Xu F, Yan L, Nie M, Yuan N, Zhang S, Zhao R, Wang H, Wu M, Zhang X, Wang J
Oncotarget 2016 Jun 14;7(24):35692-35702
Oncotarget 2016 Jun 14;7(24):35692-35702
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation.
Li J, Chen C, Ma X, Geng G, Liu B, Zhang Y, Zhang S, Zhong F, Liu C, Yin Y, Cai W, Zhang H
Nature communications 2016 Jun 13;7:11730
Nature communications 2016 Jun 13;7:11730
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Zhang W, Yin L, Tao X, Xu L, Zheng L, Han X, Xu Y, Wang C, Peng J
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Cyfip1 is downregulated in acute lymphoblastic leukemia and may be a potential biomarker in acute lymphoblastic leukemia.
Chen X, Qin L, Li P, Mo W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9285-8
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9285-8
MicroRNA-503 represses epithelial-mesenchymal transition and inhibits metastasis of osteosarcoma by targeting c-myb.
Guo X, Zhang J, Pang J, He S, Li G, Chong Y, Li C, Jiao Z, Zhang S, Shao M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9181-7
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9181-7
Aberrant expression of B7-H4 correlates with poor prognosis and suppresses tumor-infiltration of CD8+ T lymphocytes in human cholangiocarcinoma.
Zhao X, Guo F, Li Z, Jiang P, Deng X, Tian F, Li X, Wang S
Oncology reports 2016 Jul;36(1):419-27
Oncology reports 2016 Jul;36(1):419-27
The effects of D3R on TLR4 signaling involved in the regulation of METH-mediated mast cells activation.
Xue L, Geng Y, Li M, Jin YF, Ren HX, Li X, Wu F, Wang B, Cheng WY, Chen T, Chen YJ
International immunopharmacology 2016 Jul;36:187-198
International immunopharmacology 2016 Jul;36:187-198
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
Yao H, Hu C, Yin L, Tao X, Xu L, Qi Y, Han X, Xu Y, Zhao Y, Wang C, Peng J
International immunopharmacology 2016 Jul;36:132-141
International immunopharmacology 2016 Jul;36:132-141
Lentivirus-mediated inhibition of USP39 suppresses the growth of gastric cancer cells via PARP activation.
Wang X, Yu Q, Huang L, Yu P
Molecular medicine reports 2016 Jul;14(1):301-6
Molecular medicine reports 2016 Jul;14(1):301-6
Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity.
Lu YZ, Li PF, Li YZ, Luo F, Guo C, Lin B, Cao XW, Zhao J, Wang FJ
Fitoterapia 2016 Jul;112:183-90
Fitoterapia 2016 Jul;112:183-90
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tao X, Sun X, Xu L, Yin L, Han X, Qi Y, Xu Y, Zhao Y, Wang C, Peng J
Nutrients 2016 Jul 8;8(7)
Nutrients 2016 Jul 8;8(7)
The ciliary GTPase Arl13b regulates cell migration and cell cycle progression.
Pruski M, Rajnicek A, Yang Z, Clancy H, Ding YQ, McCaig CD, Lang B
Cell adhesion & migration 2016 Jul 3;10(4):393-405
Cell adhesion & migration 2016 Jul 3;10(4):393-405
TSH increases synthesis of hepatic ATP-binding cassette subfamily A member 1 in hypercholesterolemia.
Zhang T, Zhou L, Li CC, Shi H, Zhou X
Biochemical and biophysical research communications 2016 Jul 22;476(2):75-81
Biochemical and biophysical research communications 2016 Jul 22;476(2):75-81
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Zhao L, Xu L, Tao X, Han X, Yin L, Qi Y, Peng J
Molecules (Basel, Switzerland) 2016 Jul 21;21(7)
Molecules (Basel, Switzerland) 2016 Jul 21;21(7)
Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice.
Liu HZ, Tao YX, Luo P, Deng CM, Gu YP, Yang L, Zhong JP
Journal of agricultural and food chemistry 2016 Jul 20;64(28):5759-66
Journal of agricultural and food chemistry 2016 Jul 20;64(28):5759-66
Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression.
Chuang TP, Wang JY, Jao SW, Wu CC, Chen JH, Hsiao KH, Lin CY, Chen SH, Su SY, Chen YJ, Chen YT, Wu DC, Li LH
Oncotarget 2016 Jul 19;7(29):45803-45818
Oncotarget 2016 Jul 19;7(29):45803-45818
Down-regulation of adenylate kinase 5 in temporal lobe epilepsy patients and rat model.
Lai Y, Hu X, Chen G, Wang X, Zhu B
Journal of the neurological sciences 2016 Jul 15;366:20-26
Journal of the neurological sciences 2016 Jul 15;366:20-26
Propofol reduced myocardial contraction of vertebrates partly by mediating the cyclic AMP-dependent protein kinase phosphorylation pathway.
Sun X, Zhang X, Bo Q, Meng T, Lei Z, Li J, Hou Y, Yu X, Yu J
Toxicology 2016 Jul 15;365:59-66
Toxicology 2016 Jul 15;365:59-66
MiR-138-5p promotes TNF-α-induced apoptosis in human intervertebral disc degeneration by targeting SIRT1 through PTEN/PI3K/Akt signaling.
Wang B, Wang D, Yan T, Yuan H
Experimental cell research 2016 Jul 15;345(2):199-205
Experimental cell research 2016 Jul 15;345(2):199-205
Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.
Yan M, Qian YM, Yue CF, Wang ZF, Wang BC, Zhang W, Zheng FM, Liu Q
Oncotarget 2016 Jul 12;7(28):44171-44184
Oncotarget 2016 Jul 12;7(28):44171-44184
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Zhang J, Wen X, Ren XY, Li YQ, Tang XR, Wang YQ, He QM, Yang XJ, Sun Y, Liu N, Ma J
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Rosuvastatin Alleviates Type 2 Diabetic Atrial Structural and Calcium Channel Remodeling.
Pan Y, Li B, Wang J, Li X
Journal of cardiovascular pharmacology 2016 Jan;67(1):57-67
Journal of cardiovascular pharmacology 2016 Jan;67(1):57-67
Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma.
Zhang XF, Pan QZ, Pan K, Weng DS, Wang QJ, Zhao JJ, He J, Liu Q, Wang DD, Jiang SS, Zheng HX, Lv L, Chen CL, Zhang HX, Xia JC
Molecular carcinogenesis 2016 Jan;55(1):64-76
Molecular carcinogenesis 2016 Jan;55(1):64-76
Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy.
Pan XW, Li L, Huang Y, Huang H, Xu DF, Gao Y, Chen L, Ren JZ, Cao JW, Hong Y, Cui XG
Oncology reports 2016 Jan;35(1):334-42
Oncology reports 2016 Jan;35(1):334-42
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
Niewiadomski J, Zhou JQ, Roman HB, Liu X, Hirschberger LL, Locasale JW, Stipanuk MH
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
Lentivirus‑mediated knockdown of MeCP2 inhibits the growth of colorectal cancer cells in vitro.
Song N, Li K, Wang Y, Chen Z, Shi L
Molecular medicine reports 2016 Jan;13(1):860-6
Molecular medicine reports 2016 Jan;13(1):860-6
siRNA targeting TCTP suppresses osteosarcoma cell growth and induces apoptosis in vitro and in vivo.
Shen JH, Qu CB, Chu HK, Cui MY, Wang YL, Sun YX, Song YD, Li G, Shi FJ
Biotechnology and applied biochemistry 2016 Jan-Feb;63(1):5-14
Biotechnology and applied biochemistry 2016 Jan-Feb;63(1):5-14
Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathway.
Zhao XP, Zhang H, Jiao JY, Tang DX, Wu YL, Pan CB
Journal of translational medicine 2016 Jan 27;14:26
Journal of translational medicine 2016 Jan 27;14:26
Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.
Tang N, Shi L, Yu Z, Dong P, Wang C, Huo X, Zhang B, Huang S, Deng S, Liu K, Ma T, Wang X, Wu L, Ma XC
Oncotarget 2016 Jan 19;7(3):3533-47
Oncotarget 2016 Jan 19;7(3):3533-47
Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor Cells.
Zeng L, Chen Y, Liu J, Huang H, Guan R, Ji L, Chao H
Scientific reports 2016 Jan 14;6:19449
Scientific reports 2016 Jan 14;6:19449
Triptolide inhibits transcription of hTERT through down-regulation of transcription factor specificity protein 1 in primary effusion lymphoma cells.
Long C, Wang J, Guo W, Wang H, Wang C, Liu Y, Sun X
Biochemical and biophysical research communications 2016 Jan 1;469(1):87-93
Biochemical and biophysical research communications 2016 Jan 1;469(1):87-93
The ERK1/2 pathway participates in the upregulation of the expression of mesenteric artery α1 receptors by intravenous tail injections of mmLDL in mice.
Wang JJ, Chen XL, Xu CB, Jiang GF, Lin J, Liu EQ, Qin XP, Li J
Vascular pharmacology 2016 Feb;77:80-8
Vascular pharmacology 2016 Feb;77:80-8
Femtosecond UV-laser pulses to unveil protein-protein interactions in living cells.
Itri F, Monti DM, Della Ventura B, Vinciguerra R, Chino M, Gesuele F, Lombardi A, Velotta R, Altucci C, Birolo L, Piccoli R, Arciello A
Cellular and molecular life sciences : CMLS 2016 Feb;73(3):637-48
Cellular and molecular life sciences : CMLS 2016 Feb;73(3):637-48
Involvement of ICAM-1 in impaired spermatogenesis after busulfan treatment in mice.
Cai Y, Liu T, Fang F, Shen S, Xiong C
Andrologia 2016 Feb;48(1):37-44
Andrologia 2016 Feb;48(1):37-44
Jejunum-ileum circuit procedure improves glucose metabolism in diabetic rats independent of weight loss.
Wang Y, Zhang X, Liu T, Zhong M, Wan H, Liu S, Zhang G, Kassab GS, Hu S
Obesity (Silver Spring, Md.) 2016 Feb;24(2):342-51
Obesity (Silver Spring, Md.) 2016 Feb;24(2):342-51
Role of KIF2A in the progression and metastasis of human glioma.
Zhang X, Ma C, Wang Q, Liu J, Tian M, Yuan Y, Li X, Qu X
Molecular medicine reports 2016 Feb;13(2):1781-7
Molecular medicine reports 2016 Feb;13(2):1781-7
PI3K/Akt signaling pathway is involved in the neurotrophic effect of senegenin.
Pi T, Zhou XW, Cai L, Zhang W, Su CF, Wu WT, Ren XM, Luo HM
Molecular medicine reports 2016 Feb;13(2):1257-62
Molecular medicine reports 2016 Feb;13(2):1257-62
Clonorchis sinensis lysophospholipase inhibits TGF-β1-induced expression of pro-fibrogenic genes through attenuating the activations of Smad3, JNK2, and ERK1/2 in hepatic stellate cell line LX-2.
Zhou L, Shang M, Shi M, Zhao L, Lin Z, Chen T, Wu Y, Tang Z, Sun H, Yu J, Huang Y, Yu X
Parasitology research 2016 Feb;115(2):643-50
Parasitology research 2016 Feb;115(2):643-50
Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial β-endorphin expression.
Fan H, Li TF, Gong N, Wang YX
Neuropharmacology 2016 Feb;101:98-109
Neuropharmacology 2016 Feb;101:98-109
Lentivirus-mediated knockdown of CEP55 suppresses cell proliferation of breast cancer cells.
Wang Y, Jin T, Dai X, Xu J
Bioscience trends 2016 Feb;10(1):67-73
Bioscience trends 2016 Feb;10(1):67-73
TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin.
Luo Z, Zhang X, Zeng W, Su J, Yang K, Lu L, Lim CB, Tang W, Wu L, Zhao S, Jia X, Peng C, Chen X
Oncotarget 2016 Feb 9;7(6):7179-92
Oncotarget 2016 Feb 9;7(6):7179-92
Serological Evaluation of Immunity to the Varicella-Zoster Virus Based on a Novel Competitive Enzyme-Linked Immunosorbent Assay.
Liu J, Ye X, Jia J, Zhu R, Wang L, Chen C, Yang L, Wang Y, Wang W, Ye J, Li Y, Zhu H, Zhao Q, Cheng T, Xia N
Scientific reports 2016 Feb 8;6:20577
Scientific reports 2016 Feb 8;6:20577
ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy.
Peng H, Li Y, Wang C, Zhang J, Chen Y, Chen W, Cao J, Wang Y, Hu Z, Lou T
Scientific reports 2016 Feb 4;6:20304
Scientific reports 2016 Feb 4;6:20304
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology.
Wang Y, Wu F, Pan H, Zheng W, Feng C, Wang Y, Deng Z, Wang L, Luo J, Chen S
Scientific reports 2016 Feb 29;6:22244
Scientific reports 2016 Feb 29;6:22244
Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells.
Weng S, Zhou L, Deng Q, Wang J, Yu Y, Zhu J, Yuan Y
BMC gastroenterology 2016 Feb 25;16:25
BMC gastroenterology 2016 Feb 25;16:25
Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells.
Huang L, Wang H, Zhou Y, Ni D, Hu Y, Long Y, Liu J, Peng R, Zhou L, Liu Z, Lyu Z, Mao Z, Hao J, Li Y, Zhou Q
International journal of molecular sciences 2016 Feb 2;17(2)
International journal of molecular sciences 2016 Feb 2;17(2)
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Molecular cancer 2016 Feb 2;15:11
Molecular cancer 2016 Feb 2;15:11
RAB18, a protein associated with Warburg Micro syndrome, controls neuronal migration in the developing cerebral cortex.
Wu Q, Sun X, Yue W, Lu T, Ruan Y, Chen T, Zhang D
Molecular brain 2016 Feb 16;9:19
Molecular brain 2016 Feb 16;9:19
Low c-Met expression levels are prognostic for and predict the benefits of temozolomide chemotherapy in malignant gliomas.
Li MY, Yang P, Liu YW, Zhang CB, Wang KY, Wang YY, Yao K, Zhang W, Qiu XG, Li WB, Peng XX, Wang YZ, Jiang T
Scientific reports 2016 Feb 16;6:21141
Scientific reports 2016 Feb 16;6:21141
Characterization of hepatitis E virus infection in tree shrew (Tupaia belangeri chinensis).
Yu W, Yang C, Bi Y, Long F, Li Y, Wang J, Huang F
BMC infectious diseases 2016 Feb 16;16:80
BMC infectious diseases 2016 Feb 16;16:80
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
Li X, He Y, Xu Y, Huang X, Liu J, Xie M, Liu X
American journal of physiology. Lung cellular and molecular physiology 2016 Feb 15;310(4):L299-310
American journal of physiology. Lung cellular and molecular physiology 2016 Feb 15;310(4):L299-310
Knockdown of HNRNPA1 inhibits lung adenocarcinoma cell proliferation through cell cycle arrest at G0/G1 phase.
Liu X, Zhou Y, Lou Y, Zhong H
Gene 2016 Feb 1;576(2 Pt 2):791-7
Gene 2016 Feb 1;576(2 Pt 2):791-7
Down-regulated PLAC8 promotes hepatocellular carcinoma cell proliferation by enhancing PI3K/Akt/GSK3β/Wnt/β-catenin signaling.
Zou L, Chai J, Gao Y, Guan J, Liu Q, Du JJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:139-146
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:139-146
Eukaryotic translation initiation factor 3 subunit D overexpression is associated with the occurrence and development of ovarian cancer.
Lin Y, Zhang R, Zhang P
FEBS open bio 2016 Dec;6(12):1201-1210
FEBS open bio 2016 Dec;6(12):1201-1210
Pim-2 protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced apoptosis via downregulation of Bim expression.
Xu Y, Xing Y, Xu Y, Huang C, Bao H, Hong K, Cheng X
Environmental toxicology and pharmacology 2016 Dec;48:94-102
Environmental toxicology and pharmacology 2016 Dec;48:94-102
Overexpression of TSPAN8 Promotes Tumor Cell Viability and Proliferation in Nonsmall Cell Lung Cancer.
Dong Z, Zhao L, Lu S, Xiong J, Geng Z
Cancer biotherapy & radiopharmaceuticals 2016 Dec;31(10):353-359
Cancer biotherapy & radiopharmaceuticals 2016 Dec;31(10):353-359
Alteration of epoxyeicosatrienoic acids in the liver and kidney of cytochrome P450 4F2 transgenic mice.
Zhang B, Lai G, Liu X, Zhao Y
Molecular medicine reports 2016 Dec;14(6):5739-5745
Molecular medicine reports 2016 Dec;14(6):5739-5745
Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling.
Dou N, Yu S, Ye X, Yang D, Li Y, Gao Y
Oncotarget 2016 Dec 27;7(52):86161-86173
Oncotarget 2016 Dec 27;7(52):86161-86173
Developmental pattern of the neuronal intermediate filament inaa in the zebrafish retina.
Liao ML, Peng WH, Kan D, Chien CL
The Journal of comparative neurology 2016 Dec 15;524(18):3810-3826
The Journal of comparative neurology 2016 Dec 15;524(18):3810-3826
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Tang Q, Ji F, Sun W, Wang J, Guo J, Guo L, Li Y, Bao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Dec 15;23(14):1778-1786
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Dec 15;23(14):1778-1786
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy.
Chadwick JA, Swager SA, Lowe J, Welc SS, Tidball JG, Gomez-Sanchez CE, Gomez-Sanchez EP, Rafael-Fortney JA
Human molecular genetics 2016 Dec 1;25(23):5167-5177
Human molecular genetics 2016 Dec 1;25(23):5167-5177
Knockdown of GGCT inhibits cell proliferation and induces late apoptosis in human gastric cancer.
Zhang W, Chen L, Xiang H, Hu C, Shi W, Dong P, Lv W
BMC biochemistry 2016 Dec 1;17(1):19
BMC biochemistry 2016 Dec 1;17(1):19
Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin.
Tang Q, Ji F, Guo J, Wang J, Li Y, Bao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Aug;82:693-703
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Aug;82:693-703
MicroRNA-873 mediates multidrug resistance in ovarian cancer cells by targeting ABCB1.
Wu DD, Li XS, Meng XN, Yan J, Zong ZH
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):10499-506
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):10499-506
Activation of autophagy improved the neurologic outcome after cardiopulmonary resuscitation in rats.
Li X, Liu YJ, Xia JM, Zeng XY, Liao XX, Wei HY, Hu CL, Jing XL, Dai G
The American journal of emergency medicine 2016 Aug;34(8):1511-8
The American journal of emergency medicine 2016 Aug;34(8):1511-8
Echinacoside Protects Against MPP(+)-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation.
Zhao Q, Yang X, Cai D, Ye L, Hou Y, Zhang L, Cheng J, Shen Y, Wang K, Bai Y
Neuroscience bulletin 2016 Aug;32(4):349-62
Neuroscience bulletin 2016 Aug;32(4):349-62
Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells.
Pan Y, Bai J, Shen F, Sun L, He Q, Su B
Molecular medicine reports 2016 Aug;14(2):1751-5
Molecular medicine reports 2016 Aug;14(2):1751-5
Induction of adipose-derived stem cells into Schwann-like cells and observation of Schwann-like cell proliferation.
Fu X, Tong Z, Li Q, Niu Q, Zhang Z, Tong X, Tong L, Zhang X
Molecular medicine reports 2016 Aug;14(2):1187-93
Molecular medicine reports 2016 Aug;14(2):1187-93
N-ethylmaleimide‑sensitive factor siRNA inhibits the release of Weibel-Palade bodies in endothelial cells.
Zhou Y, Yang SX, Yue YN, Wei XF, Liu Y
Molecular medicine reports 2016 Aug;14(2):1061-6
Molecular medicine reports 2016 Aug;14(2):1061-6
Inhibitory effect of RNA-mediated knockdown of zinc finger protein 91 pseudogene on pancreatic cancer cell growth and invasion.
Huang W, Li N, Hu J, Wang L
Oncology letters 2016 Aug;12(2):1343-1348
Oncology letters 2016 Aug;12(2):1343-1348
Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK.
Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, Gong P
Oncology letters 2016 Aug;12(2):1058-1066
Oncology letters 2016 Aug;12(2):1058-1066
Rapid generation of functional hepatocyte-like cells from human adipose-derived stem cells.
Fu Y, Deng J, Jiang Q, Wang Y, Zhang Y, Yao Y, Cheng F, Chen X, Xu F, Huang M, Yang Y, Zhang S, Yu D, Zhao RC, Wei Y, Deng H
Stem cell research & therapy 2016 Aug 5;7(1):105
Stem cell research & therapy 2016 Aug 5;7(1):105
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy.
Zhang J, Chen K, Wang L, Wan X, Shrestha C, Zhou J, Mo Z
Biochemical and biophysical research communications 2016 Aug 5;476(4):299-305
Biochemical and biophysical research communications 2016 Aug 5;476(4):299-305
Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats.
Yin J, You S, Li N, Jiao S, Hu H, Xue M, Wang Y, Cheng W, Liu J, Xu M, Yan S, Li X
Respiratory research 2016 Aug 4;17(1):99
Respiratory research 2016 Aug 4;17(1):99
CHIP promotes thyroid cancer proliferation via activation of the MAPK and AKT pathways.
Zhang L, Liu L, He X, Shen Y, Liu X, Wei J, Yu F, Tian J
Biochemical and biophysical research communications 2016 Aug 26;477(3):356-62
Biochemical and biophysical research communications 2016 Aug 26;477(3):356-62
Wnt/β-Catenin Signaling Mediated-UCH-L1 Expression in Podocytes of Diabetic Nephropathy.
Zhang H, Luo W, Sun Y, Qiao Y, Zhang L, Zhao Z, Lv S
International journal of molecular sciences 2016 Aug 25;17(9)
International journal of molecular sciences 2016 Aug 25;17(9)
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, Du Z, Li J, Duan Y, Du G
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
CCBE1 promotes GIST development through enhancing angiogenesis and mediating resistance to imatinib.
Tian GA, Zhu CC, Zhang XX, Zhu L, Yang XM, Jiang SH, Li RK, Tu L, Wang Y, Zhuang C, He P, Li Q, Cao XY, Cao H, Zhang ZG
Scientific reports 2016 Aug 10;6:31071
Scientific reports 2016 Aug 10;6:31071
Retraction: Expression of peroxisome proliferator-activated receptor gamma (PPARγ) in porcine endometrium and placenta.
Zhang J, Xu J, Yang Q, Yuan A, Yang L, Xue L
Journal of veterinary science 2016 Aug 10;
Journal of veterinary science 2016 Aug 10;
PRL-3 promotes gastric cancer migration and invasion through a NF-κB-HIF-1α-miR-210 axis.
Zhang C, Tian W, Meng L, Qu L, Shou C
Journal of molecular medicine (Berlin, Germany) 2016 Apr;94(4):401-15
Journal of molecular medicine (Berlin, Germany) 2016 Apr;94(4):401-15
Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein.
Zhang J, Huang F, Tan L, Bai C, Chen B, Liu J, Liang J, Liu C, Zhang S, Lu G, Chen Y, Zhang H
Journal of virology 2016 Apr;90(8):3966-3980
Journal of virology 2016 Apr;90(8):3966-3980
Tumor-suppressive functions of long-chain acyl-CoA synthetase 4 in gastric cancer.
Ye X, Zhang Y, Wang X, Li Y, Gao Y
IUBMB life 2016 Apr;68(4):320-7
IUBMB life 2016 Apr;68(4):320-7
Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells.
Long C, Guo W, Zhou H, Wang J, Wang H, Sun X
International journal of oncology 2016 Apr;48(4):1519-30
International journal of oncology 2016 Apr;48(4):1519-30
Diagnostic and prognostic value of tissue and circulating levels of Ephrin-A2 in prostate cancer.
Li S, Wu Z, Chen Y, Kang Z, Wang H, He P, Zhang X, Hu T, Zhang Q, Cai Y, Xu X, Guan M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):5365-74
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):5365-74
SATB2 suppresses gastric cancer cell proliferation and migration.
Wu L, Chen J, Qin Y, Mo X, Huang M, Ru H, Yang Y, Liu J, Lin Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):4597-602
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):4597-602
Epb41l3 suppresses esophageal squamous cell carcinoma invasion and inhibits MMP2 and MMP9 expression.
Zeng R, Huang JP, Li XF, Xiong WB, Wu G, Jiang ZJ, Song SJ, Li JQ, Zheng YF, Zhang JR
Cell biochemistry and function 2016 Apr;34(3):133-41
Cell biochemistry and function 2016 Apr;34(3):133-41
Lentivirus-Mediated Knockdown of CTHRC1 Inhibits Osteosarcoma Cell Proliferation and Migration.
Sang W, Zhu L, Ma J, Lu H, Wang C
Cancer biotherapy & radiopharmaceuticals 2016 Apr;31(3):91-8
Cancer biotherapy & radiopharmaceuticals 2016 Apr;31(3):91-8
Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia.
Chen L, Wang W, Cao L, Li Z, Wang X
Molecules and cells 2016 Apr 30;39(4):330-6
Molecules and cells 2016 Apr 30;39(4):330-6
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, Fei Y, Li C
Scientific reports 2016 Apr 25;6:24859
Scientific reports 2016 Apr 25;6:24859
HBsAg blocks TYPE I IFN induced up-regulation of A3G through inhibition of STAT3.
Xu F, Song H, Li N, Tan G
Biochemical and biophysical research communications 2016 Apr 22;473(1):219-223
Biochemical and biophysical research communications 2016 Apr 22;473(1):219-223
MicroRNA-133b targets glutathione S-transferase π expression to increase ovarian cancer cell sensitivity to chemotherapy drugs.
Chen S, Jiao JW, Sun KX, Zong ZH, Zhao Y
Drug design, development and therapy 2015;9:5225-35
Drug design, development and therapy 2015;9:5225-35
Lentivirus-Mediated knockdown of tectonic family member 1 inhibits medulloblastoma cell proliferation.
Jing J, Wang C, Liang Q, Zhao Y, Zhao Q, Wang S, Ma J
International journal of clinical and experimental medicine 2015;8(8):13127-35
International journal of clinical and experimental medicine 2015;8(8):13127-35
MiRNA-15a inhibits proliferation, migration and invasion by targeting TNFAIP1 in human osteosarcoma cells.
Tian X, Zhang J, Yan L, Dong JM, Guo Q
International journal of clinical and experimental pathology 2015;8(6):6442-9
International journal of clinical and experimental pathology 2015;8(6):6442-9
PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.
Piao MX, Bai JW, Zhang PF, Zhang YZ
International journal of clinical and experimental pathology 2015;8(3):2787-94
International journal of clinical and experimental pathology 2015;8(3):2787-94
Lentivirus-mediated TPD52L2 depletion inhibits the proliferation of liver cancer cells in vitro.
Pan ZY, Yang Y, Pan H, Zhang J, Liu H, Yang Y, Huang G, Yin L, Huang J, Zhou WP
International journal of clinical and experimental medicine 2015;8(2):2334-41
International journal of clinical and experimental medicine 2015;8(2):2334-41
Levofloxacin increases apoptosis of rat annulus fibrosus cells via the mechanism of upregulating MMP-2 and MMP-13.
Wei HK, Yang SD, Bai ZL, Zhang X, Yang DL, Ding WY
International journal of clinical and experimental medicine 2015;8(11):20198-207
International journal of clinical and experimental medicine 2015;8(11):20198-207
Effect of prostaglandin reductase 1 (PTGR1) on gastric carcinoma using lentivirus-mediated system.
Yang S, Luo F, Wang J, Mao X, Chen Z, Wang Z, Guo F
International journal of clinical and experimental pathology 2015;8(11):14493-9
International journal of clinical and experimental pathology 2015;8(11):14493-9
MicroRNA-141 inhibits vascular smooth muscle cell proliferation through targeting PAPP-A.
Zhang Y, Chen B, Ming L, Qin H, Zheng L, Yue Z, Cheng Z, Wang Y, Zhang D, Liu C, Bin W, Hao Q, Song F, Ji B
International journal of clinical and experimental pathology 2015;8(11):14401-8
International journal of clinical and experimental pathology 2015;8(11):14401-8
MicroRNA-130a inhibits cell proliferation, invasion and migration in human breast cancer by targeting the RAB5A.
Pan Y, Wang R, Zhang F, Chen Y, Lv Q, Long G, Yang K
International journal of clinical and experimental pathology 2015;8(1):384-93
International journal of clinical and experimental pathology 2015;8(1):384-93
Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells.
Yu L, Wang X, Zhu D, Ding W, Wang L, Zhang C, Jiang X, Shen H, Liao S, Ma D, Hu Z, Wang H
OncoTargets and therapy 2015;8:37-44
OncoTargets and therapy 2015;8:37-44
PP4R1 accelerates cell growth and proliferation in HepG2 hepatocellular carcinoma.
Wu G, Ma Z, Qian J, Liu B
OncoTargets and therapy 2015;8:2067-74
OncoTargets and therapy 2015;8:2067-74
Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest.
Xie R, Zhang Y, Shen C, Cao X, Gu S, Che X
OncoTargets and therapy 2015;8:1119-27
OncoTargets and therapy 2015;8:1119-27
The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis.
Chen Y, Liu H, Guan Y, Wang Q, Zhou F, Jie L, Ju J, Pu L, Du H, Wang X
American journal of translational research 2015;7(9):1574-87
American journal of translational research 2015;7(9):1574-87
Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways.
Yang D, Wang LL, Dong TT, Shen YH, Guo XS, Liu CY, Liu J, Zhang P, Li J, Sun YP
American journal of cancer research 2015;5(10):3085-97
American journal of cancer research 2015;5(10):3085-97
Anti-fibrotic effects of neferine on carbon tetrachloride-induced hepatic fibrosis in mice.
Chen MS, Zhang JH, Wang JL, Gao L, Chen XX, Xiao JH
The American journal of Chinese medicine 2015;43(2):231-40
The American journal of Chinese medicine 2015;43(2):231-40
Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway.
Yang ZT, Li Z, Wang XG, Tan T, Yi F, Zhu H, Zhao JP, Zhou XF
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2360-70
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2360-70
MicroRNA-181a inhibits tumor proliferation, invasiveness, and metastasis and is downregulated in gastric cancer.
Lin F, Li Y, Yan S, Liu S, Qian W, Shen D, Lin Q, Mao W
Oncology research 2015;22(2):75-84
Oncology research 2015;22(2):75-84
Downregulation of Spinal G Protein-Coupled Kinase 2 Abolished the Antiallodynic Effect of Electroacupuncture.
Liu H, Liu SB, Li Q, Wang H, Wang YQ, Mao-Ying QL
Evidence-based complementary and alternative medicine : eCAM 2015;2015:848603
Evidence-based complementary and alternative medicine : eCAM 2015;2015:848603
Bone Marrow-Derived Mesenchymal Stem Cells Repair Necrotic Pancreatic Tissue and Promote Angiogenesis by Secreting Cellular Growth Factors Involved in the SDF-1 α /CXCR4 Axis in Rats.
Qian D, Gong J, He Z, Hua J, Lin S, Xu C, Meng H, Song Z
Stem cells international 2015;2015:306836
Stem cells international 2015;2015:306836
Cardioprotective effect of propofol against oxygen glucose deprivation and reperfusion injury in H9c2 cells.
Zhao D, Li Q, Huang Q, Li X, Yin M, Wang Z, Hong J
Oxidative medicine and cellular longevity 2015;2015:184938
Oxidative medicine and cellular longevity 2015;2015:184938
LPS Induces Occludin Dysregulation in Cerebral Microvascular Endothelial Cells via MAPK Signaling and Augmenting MMP-2 Levels.
Qin LH, Huang W, Mo XA, Chen YL, Wu XH
Oxidative medicine and cellular longevity 2015;2015:120641
Oxidative medicine and cellular longevity 2015;2015:120641
SIRT7 Exhibits Oncogenic Potential in Human Ovarian Cancer Cells.
Wang HL, Lu RQ, Xie SH, Zheng H, Wen XM, Gao X, Guo L
Asian Pacific journal of cancer prevention : APJCP 2015;16(8):3573-7
Asian Pacific journal of cancer prevention : APJCP 2015;16(8):3573-7
Silencing of Rac3 inhibits proliferation and induces apoptosis of human lung cancer cells.
Liu TQ, Wang GB, Li ZJ, Tong XD, Liu HX
Asian Pacific journal of cancer prevention : APJCP 2015;16(7):3061-5
Asian Pacific journal of cancer prevention : APJCP 2015;16(7):3061-5
MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin.
Huang N, Wu J, Qiu W, Lyu Q, He J, Xie W, Xu N, Zhang Y
Cancer biology & therapy 2015;16(6):941-8
Cancer biology & therapy 2015;16(6):941-8
siRNA-mediated knockdown of JUB expression suppresses the proliferation of glioblastoma cells.
Ouyang H, Guo Z, Cheng Z, Guo Y
Cancer biomarkers : section A of Disease markers 2015;15(4):477-84
Cancer biomarkers : section A of Disease markers 2015;15(4):477-84
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells.
Zhao X, Fang Y, Yang Y, Qin Y, Wu P, Wang T, Lai H, Meng L, Wang D, Zheng Z, Lu X, Zhang H, Gao Q, Zhou J, Ma D
Autophagy 2015;11(10):1849-63
Autophagy 2015;11(10):1849-63
The Cardioprotective Effect of Vitamin E (Alpha-Tocopherol) Is Strongly Related to Age and Gender in Mice.
Hu XX, Fu L, Li Y, Lin ZB, Liu X, Wang JF, Chen YX, Wang ZP, Zhang X, Ou ZJ, Ou JS
PloS one 2015;10(9):e0137405
PloS one 2015;10(9):e0137405
Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.
Yang LP, Jiang FJ, Wu GS, Deng K, Wen M, Zhou X, Hong X, Zhu MX, Luo HR
PloS one 2015;10(8):e0136255
PloS one 2015;10(8):e0136255
A Cell Electrofusion Chip for Somatic Cells Reprogramming.
Wu W, Qu Y, Hu N, Zeng Y, Yang J, Xu H, Yin ZQ
PloS one 2015;10(7):e0131966
PloS one 2015;10(7):e0131966
MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2.
Wu L, Chen J, Ding C, Wei S, Zhu Y, Yang W, Zhang X, Wei X, Han D
PloS one 2015;10(6):e0130124
PloS one 2015;10(6):e0130124
Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome.
Wu B, Shi Y, Gong X, Yu L, Chen Q, Wang J, Sun Z
PloS one 2015;10(5):e0127595
PloS one 2015;10(5):e0127595
Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.
Xu Y, Cao J, Huang S, Feng D, Zhang W, Zhu X, Yan X
PloS one 2015;10(4):e0124378
PloS one 2015;10(4):e0124378
Resveratrol inhibits enterovirus 71 replication and pro-inflammatory cytokine secretion in rhabdosarcoma cells through blocking IKKs/NF-κB signaling pathway.
Zhang L, Li Y, Gu Z, Wang Y, Shi M, Ji Y, Sun J, Xu X, Zhang L, Jiang J, Shi W
PloS one 2015;10(2):e0116879
PloS one 2015;10(2):e0116879
The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes.
Tu X, Kuang Z, Gong X, Shi Y, Yu L, Shi H, Wang J, Sun Z
PloS one 2015;10(11):e0141800
PloS one 2015;10(11):e0141800
Cytotoxicity of various types of gold-mesoporous silica nanoparticles in human breast cancer cells.
Liu G, Li Q, Ni W, Zhang N, Zheng X, Wang Y, Shao D, Tai G
International journal of nanomedicine 2015;10:6075-87
International journal of nanomedicine 2015;10:6075-87
Decreased expression of RPS15A suppresses proliferation of lung cancer cells.
Zhao X, Shen L, Feng Y, Yu H, Wu X, Chang J, Shen X, Qiao J, Wang J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(9):6733-40
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(9):6733-40
MiR-197 induces Taxol resistance in human ovarian cancer cells by regulating NLK.
Zou D, Wang D, Li R, Tang Y, Yuan L, Long X, Zhou Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(9):6725-32
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(9):6725-32
PU.1-Regulated Long Noncoding RNA lnc-MC Controls Human Monocyte/Macrophage Differentiation through Interaction with MicroRNA 199a-5p.
Chen MT, Lin HS, Shen C, Ma YN, Wang F, Zhao HL, Yu J, Zhang JW
Molecular and cellular biology 2015 Sep;35(18):3212-24
Molecular and cellular biology 2015 Sep;35(18):3212-24
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Huang W, Zhong W, Xu J, Su B, Huang G, Du J, Liu Q
Oncology reports 2015 Sep;34(3):1510-6
Oncology reports 2015 Sep;34(3):1510-6
Lentivirus-Mediated Short-Hairpin RNA Targeting Protein Phosphatase 4 Regulatory Subunit 1 Inhibits Growth in Breast Cancer.
Qi Y, Hu T, Li K, Ye R, Ye Z
Journal of breast cancer 2015 Sep;18(3):218-24
Journal of breast cancer 2015 Sep;18(3):218-24
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY
PLoS genetics 2015 Sep;11(9):e1005357
PLoS genetics 2015 Sep;11(9):e1005357
Inhibition of protein phosphatase 5 (PP5) suppresses survival and growth of colorectal cancer cells.
Wang J, Zhu J, Dong M, Yu H, Dai X, Li K
Biotechnology and applied biochemistry 2015 Sep-Oct;62(5):621-7
Biotechnology and applied biochemistry 2015 Sep-Oct;62(5):621-7
Delivery of Adipose-Derived Stem Cells Attenuates Adipose Tissue Inflammation and Insulin Resistance in Obese Mice Through Remodeling Macrophage Phenotypes.
Shang Q, Bai Y, Wang G, Song Q, Guo C, Zhang L, Wang Q
Stem cells and development 2015 Sep 1;24(17):2052-64
Stem cells and development 2015 Sep 1;24(17):2052-64
Lentivirus-Mediated Silencing of Myosin VI Inhibits Proliferation and Cell Cycle Progression in Human Lung Cancer Cells.
Yu H, Zhu Z, Chang J, Wang J, Shen X
Chemical biology & drug design 2015 Oct;86(4):606-13
Chemical biology & drug design 2015 Oct;86(4):606-13
A simple method for differentiation of H9 cells into neuroectoderm.
Liu A, Zhang D, Liu L, Gong J, Liu C
Tissue & cell 2015 Oct;47(5):471-7
Tissue & cell 2015 Oct;47(5):471-7
Tectonic‑1 contributes to the growth and migration of prostate cancer cells in vitro.
Wang Z, Gao Y, Liu Y, Chen J, Wang J, Gan S, Xu D, Cui X
International journal of molecular medicine 2015 Oct;36(4):931-8
International journal of molecular medicine 2015 Oct;36(4):931-8
Downregulation of ubiquitin-associated protein 2-like with a short hairpin RNA inhibits human glioma cell growth in vitro.
Zhao B, Zong G, Xie Y, Li J, Wang H, Bian E
International journal of molecular medicine 2015 Oct;36(4):1012-8
International journal of molecular medicine 2015 Oct;36(4):1012-8
Lentivirus-Mediated Knockdown of Myosin VI Inhibits Cell Proliferation of Breast Cancer Cell.
Wang H, Wang B, Zhu W, Yang Z
Cancer biotherapy & radiopharmaceuticals 2015 Oct;30(8):330-5
Cancer biotherapy & radiopharmaceuticals 2015 Oct;30(8):330-5
Small nuclear ribonucleoprotein associated polypeptide N accelerates cell proliferation in pancreatic adenocarcinoma.
Ma J, Zhang Z, Wang J
Molecular medicine reports 2015 Oct;12(4):6060-4
Molecular medicine reports 2015 Oct;12(4):6060-4
Lentivirus‑delivered nemo‑like kinase small interfering RNA inhibits laryngeal cancer cell proliferation in vitro.
Tai J, Rao Y, Fang J, Huang Z, Yu Z, Chen X, Zhou W, Xiao X, Long T, Han Y, Liu Q, Li A, Ni X
Molecular medicine reports 2015 Oct;12(4):5619-24
Molecular medicine reports 2015 Oct;12(4):5619-24
The Steroid Hormone 20-Hydroxyecdysone Up-regulates Ste-20 Family Serine/Threonine Kinase Hippo to Induce Programmed Cell Death.
Dong DJ, Jing YP, Liu W, Wang JX, Zhao XF
The Journal of biological chemistry 2015 Oct 9;290(41):24738-46
The Journal of biological chemistry 2015 Oct 9;290(41):24738-46
Phosphorylation of STAT3 mediates the induction of cyclooxygenase-2 by cortisol in the human amnion at parturition.
Wang W, Guo C, Zhu P, Lu J, Li W, Liu C, Xie H, Myatt L, Chen ZJ, Sun K
Science signaling 2015 Oct 27;8(400):ra106
Science signaling 2015 Oct 27;8(400):ra106
Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells.
Chen J, Wang C, Lan W, Huang C, Lin M, Wang Z, Liang W, Iwamoto A, Yang X, Liu H
Marine drugs 2015 Oct 2;13(10):6259-73
Marine drugs 2015 Oct 2;13(10):6259-73
Critical role of CDK11(p58) in human breast cancer growth and angiogenesis.
Chi Y, Huang S, Peng H, Liu M, Zhao J, Shao Z, Wu J
BMC cancer 2015 Oct 15;15:701
BMC cancer 2015 Oct 15;15:701
BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.
Liao S, Du R, Wang L, Qu Z, Cui X, Li C, Liu F, Huang M, Wang J, Chen J, Gao M, Yu S, Tang Z, Li DW, Jiang T, Liu M
The international journal of biochemistry & cell biology 2015 Nov;68:78-86
The international journal of biochemistry & cell biology 2015 Nov;68:78-86
Analysis of the differential secretome of nasopharyngeal carcinoma cell lines CNE-2R and CNE-2.
Chen ZT, Li L, Guo Y, Qu S, Zhao W, Chen H, Su F, Yin J, Mo QY, Zhu XD
Oncology reports 2015 Nov;34(5):2477-88
Oncology reports 2015 Nov;34(5):2477-88
Claudin 8 Contributes to Malignant Proliferation in Human Osteosarcoma U2OS Cells.
Xu J, Yang Y, Hao P, Ding X
Cancer biotherapy & radiopharmaceuticals 2015 Nov;30(9):400-4
Cancer biotherapy & radiopharmaceuticals 2015 Nov;30(9):400-4
Mechanism of programmed cell death factor 4/nuclear factor-κB signaling pathway in porcine coronary micro-embolization-induced cardiac dysfunction.
Su Q, Li L, Wang J, Zhou Y, Liu Y
Experimental biology and medicine (Maywood, N.J.) 2015 Nov;240(11):1426-33
Experimental biology and medicine (Maywood, N.J.) 2015 Nov;240(11):1426-33
Knockdown of myosin VI by lentivirus-mediated short hairpin RNA suppresses proliferation of melanoma.
Li H, Zhou F, Wang H, Lin D, Chen G, Zuo X, Sun L, Zhang X, Yang S
Molecular medicine reports 2015 Nov;12(5):6801-6
Molecular medicine reports 2015 Nov;12(5):6801-6
ZFP36L1 promotes monocyte/macrophage differentiation by repressing CDK6.
Chen MT, Dong L, Zhang XH, Yin XL, Ning HM, Shen C, Su R, Li F, Song L, Ma YN, Wang F, Zhao HL, Yu J, Zhang JW
Scientific reports 2015 Nov 6;5:16229
Scientific reports 2015 Nov 6;5:16229
Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure.
Ding C, Wu Z, Huang L, Wang Y, Xue J, Chen S, Deng Z, Wang L, Song Z, Chen S
Scientific reports 2015 Nov 4;5:16064
Scientific reports 2015 Nov 4;5:16064
Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis.
Chen FY, Zhou J, Guo N, Ma WG, Huang X, Wang H, Yuan ZY
Biochemical and biophysical research communications 2015 Nov 27;467(4):872-8
Biochemical and biophysical research communications 2015 Nov 27;467(4):872-8
A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1.
Ying Q, Ansong E, Diamond AM, Yang W
International journal of molecular sciences 2015 Nov 18;16(11):27599-608
International journal of molecular sciences 2015 Nov 18;16(11):27599-608
Reduction of progesterone, estradiol and hCG secretion by perfluorooctane sulfonate via induction of apoptosis in human placental syncytiotrophoblasts.
Zhang N, Wang WS, Li WJ, Liu C, Wang Y, Sun K
Placenta 2015 May;36(5):575-80
Placenta 2015 May;36(5):575-80
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Zhang Y, Zhang X, Huang J, Dong Q
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress.
Han Y, Wang L, Yao QP, Zhang P, Liu B, Wang GL, Shen BR, Cheng B, Wang Y, Jiang ZL, Qi YX
Biochimica et biophysica acta 2015 May;1853(5):1165-73
Biochimica et biophysica acta 2015 May;1853(5):1165-73
Immunoglobulin-like transcript 4 promotes tumor progression and metastasis and up-regulates VEGF-C expression via ERK signaling pathway in non-small cell lung cancer.
Zhang P, Guo X, Li J, Yu S, Wang L, Jiang G, Yang D, Wei Z, Zhang N, Liu J, Sun Y
Oncotarget 2015 May 30;6(15):13550-63
Oncotarget 2015 May 30;6(15):13550-63
The expression of CXCL13 and its relation to unfavorable clinical characteristics in young breast cancer.
Chen L, Huang Z, Yao G, Lyu X, Li J, Hu X, Cai Y, Li W, Li X, Ye C
Journal of translational medicine 2015 May 20;13:168
Journal of translational medicine 2015 May 20;13:168
Characterization of phase I metabolism of resibufogenin and evaluation of the metabolic effects on its antitumor activity and toxicity.
Ning J, Yu ZL, Hu LH, Wang C, Huo XK, Deng S, Hou J, Wu JJ, Ge GB, Ma XC, Yang L
Drug metabolism and disposition: the biological fate of chemicals 2015 Mar;43(3):299-308
Drug metabolism and disposition: the biological fate of chemicals 2015 Mar;43(3):299-308
Knockdown of tumor protein D52-like 2 induces cell growth inhibition and apoptosis in oral squamous cell carcinoma.
He Y, Chen F, Cai Y, Chen S
Cell biology international 2015 Mar;39(3):264-71
Cell biology international 2015 Mar;39(3):264-71
Homolog of allograft inflammatory factor-1 induces macrophage migration during innate immune response in leech.
Schorn T, Drago F, Tettamanti G, Valvassori R, de Eguileor M, Vizioli J, Grimaldi A
Cell and tissue research 2015 Mar;359(3):853-64
Cell and tissue research 2015 Mar;359(3):853-64
17β-estradiol protects against apoptosis induced by interleukin-1β in rat nucleus pulposus cells by down-regulating MMP-3 and MMP-13.
Yang SD, Yang DL, Sun YP, Wang BL, Ma L, Feng SQ, Ding WY
Apoptosis : an international journal on programmed cell death 2015 Mar;20(3):348-57
Apoptosis : an international journal on programmed cell death 2015 Mar;20(3):348-57
Docosahexanoic acid modifies low-density lipoprotein receptor abundance in HepG2 cells via suppression of the LXRα-Idol pathway.
Zhou Y, Guo Y, Zhuang X, Du Z
Molecular medicine reports 2015 Mar;11(3):2329-33
Molecular medicine reports 2015 Mar;11(3):2329-33
P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury.
Li L, Hu J, He T, Zhang Q, Yang X, Lan X, Zhang D, Mei H, Chen B, Huang Y
Scientific reports 2015 Mar 9;5:8895
Scientific reports 2015 Mar 9;5:8895
Lentivirus mediated silencing of ubiquitin specific peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro.
Pan Z, Pan H, Zhang J, Yang Y, Liu H, Yang Y, Huang G, Ni J, Huang J, Zhou W
Biological research 2015 Mar 19;48(1):18
Biological research 2015 Mar 19;48(1):18
Analgesic Effect of Intrathecal Administration of Chemokine Receptor CCR2 Antagonist is Related to Change in Spinal NR2B, nNOS, and SIGIRR Expression in Rat with Bone Cancer Pain.
Ren F, Jiao H, Cai H
Cell biochemistry and biophysics 2015 Jun;72(2):611-6
Cell biochemistry and biophysics 2015 Jun;72(2):611-6
MicroRNA-93 regulates collagen loss by targeting MMP3 in human nucleus pulposus cells.
Jing W, Jiang W
Cell proliferation 2015 Jun;48(3):284-92
Cell proliferation 2015 Jun;48(3):284-92
The effects of PBDE-209 exposure during pregnancy on placental ET-1 and eNOS expression and the birth weight of offspring.
Du P, Li Z, Du L, Zhang H, Zhou Y, Sun W, Xiao X, He Y, Sun B, Yu Y, Chen D
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2015 Jun;43:86-91
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2015 Jun;43:86-91
OSM is overexpressed in knee osteoarthritis and Notch signaling is involved in the effects of OSM on MC3T3-E1 cell proliferation and differentiation.
Ni J, Yuan XM, Yao Q, Peng LB
International journal of molecular medicine 2015 Jun;35(6):1755-60
International journal of molecular medicine 2015 Jun;35(6):1755-60
γ-Glutamylcyclotransferase Knockdown Inhibits Growth of Lung Cancer Cells Through G0/G1 Phase Arrest.
Lin Z, Xiong L, Zhou J, Wang J, Li Z, Hu H, Lin Q
Cancer biotherapy & radiopharmaceuticals 2015 Jun;30(5):211-6
Cancer biotherapy & radiopharmaceuticals 2015 Jun;30(5):211-6
A novel Cx50 (GJA8) p.H277Y mutation associated with autosomal dominant congenital cataract identified with targeted next-generation sequencing.
Chen C, Sun Q, Gu M, Liu K, Sun Y, Xu X
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2015 Jun;253(6):915-24
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2015 Jun;253(6):915-24
Indomethacin induces apoptosis in the EC109 esophageal cancer cell line by releasing second mitochondria-derived activator of caspase and activating caspase-3.
Qin S, Xu C, Li S, Yang C, Sun X, Wang X, Tang SC, Ren H
Molecular medicine reports 2015 Jun;11(6):4694-700
Molecular medicine reports 2015 Jun;11(6):4694-700
Advanced glycation end products induce glomerular endothelial cell hyperpermeability by upregulating matrix metalloproteinase activity.
Luo P, Peng H, Li C, Ye Z, Tang H, Tang Y, Chen C, Lou T
Molecular medicine reports 2015 Jun;11(6):4447-53
Molecular medicine reports 2015 Jun;11(6):4447-53
Inhibition of microRNA-25 by tumor necrosis factor α is critical in the modulation of vascular smooth muscle cell proliferation.
Qi L, Zhi J, Zhang T, Cao X, Sun L, Xu Y, Li X
Molecular medicine reports 2015 Jun;11(6):4353-8
Molecular medicine reports 2015 Jun;11(6):4353-8
Polyphenol-rich extract of Pimenta dioica berries (Allspice) kills breast cancer cells by autophagy and delays growth of triple negative breast cancer in athymic mice.
Zhang L, Shamaladevi N, Jayaprakasha GK, Patil BS, Lokeshwar BL
Oncotarget 2015 Jun 30;6(18):16379-95
Oncotarget 2015 Jun 30;6(18):16379-95
YY1 regulates melanoma tumorigenesis through a miR-9 ~ RYBP axis.
Zhao G, Li Q, Wang A, Jiao J
Journal of experimental & clinical cancer research : CR 2015 Jun 24;34(1):66
Journal of experimental & clinical cancer research : CR 2015 Jun 24;34(1):66
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
Nutrients 2015 Jun 15;7(6):4829-50
Impact of a novel homozygous mutation in nicotinamide nucleotide transhydrogenase on mitochondrial DNA integrity in a case of familial glucocorticoid deficiency.
Fujisawa Y, Napoli E, Wong S, Song G, Yamaguchi R, Matsui T, Nagasaki K, Ogata T, Giulivi C
BBA clinical 2015 Jun 1;3:70-78
BBA clinical 2015 Jun 1;3:70-78
Role of Endoplasmic Reticulum Stress in Brain Damage After Cardiopulmonary Resuscitation in Rats.
Zhang J, Xie X, Pan H, Wu Z, Lu W, Yang G
Shock (Augusta, Ga.) 2015 Jul;44(1):65-71
Shock (Augusta, Ga.) 2015 Jul;44(1):65-71
Serine/Threonine Protein Phosphatase-5 Accelerates Cell Growth and Migration in Human Glioma.
Zhi X, Zhang H, He C, Wei Y, Bian L, Li G
Cellular and molecular neurobiology 2015 Jul;35(5):669-77
Cellular and molecular neurobiology 2015 Jul;35(5):669-77
Knockdown of eIF3d inhibits cell proliferation through G2/M phase arrest in non-small cell lung cancer.
Lin Z, Xiong L, Lin Q
Medical oncology (Northwood, London, England) 2015 Jul;32(7):183
Medical oncology (Northwood, London, England) 2015 Jul;32(7):183
A novel biphenyl urea derivate inhibits the invasion of breast cancer through the modulation of CXCR4.
Zhan Y, Zhang H, Li J, Zhang Y, Zhang J, He L
Journal of cellular and molecular medicine 2015 Jul;19(7):1614-23
Journal of cellular and molecular medicine 2015 Jul;19(7):1614-23
HSP27 phosphorylation protects against endothelial barrier dysfunction under burn serum challenge.
Sun HB, Ren X, Liu J, Guo XW, Jiang XP, Zhang DX, Huang YS, Zhang JP
Biochemical and biophysical research communications 2015 Jul 31;463(3):377-83
Biochemical and biophysical research communications 2015 Jul 31;463(3):377-83
Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B.
Li S, Deng Z, Fu J, Xu C, Xin G, Wu Z, Luo J, Wang G, Zhang S, Zhang B, Zou F, Jiang Q, Zhang C
The Journal of biological chemistry 2015 Jul 10;290(28):17546-58
The Journal of biological chemistry 2015 Jul 10;290(28):17546-58
Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.
Zhu M, Fang T, Li S, Meng K, Guo D
Journal of immunology (Baltimore, Md. : 1950) 2015 Jul 1;195(1):289-97
Journal of immunology (Baltimore, Md. : 1950) 2015 Jul 1;195(1):289-97
Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.
Zhou W, Wang Z, Shen N, Pi W, Jiang W, Huang J, Hu Y, Li X, Sun L
Molecular and cellular biochemistry 2015 Jan;398(1-2):11-9
Molecular and cellular biochemistry 2015 Jan;398(1-2):11-9
miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes.
Duan X, Zohaib A, Li Y, Zhu B, Ye J, Wan S, Xu Q, Song Y, Chen H, Cao S
Cellular signalling 2015 Jan;27(1):61-8
Cellular signalling 2015 Jan;27(1):61-8
Employment of digital gene expression profiling to identify potential pathogenic and therapeutic targets of fulminant hepatic failure.
Chen EQ, Bai L, Gong DY, Tang H
Journal of translational medicine 2015 Jan 27;13:22
Journal of translational medicine 2015 Jan 27;13:22
Translation of 5' leaders is pervasive in genes resistant to eIF2 repression.
Andreev DE, O'Connor PB, Fahey C, Kenny EM, Terenin IM, Dmitriev SE, Cormican P, Morris DW, Shatsky IN, Baranov PV
eLife 2015 Jan 26;4:e03971
eLife 2015 Jan 26;4:e03971
Potent effects of dioscin against obesity in mice.
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973
Scientific reports 2015 Jan 22;5:7973
Interleukin 7 up-regulates CD95 protein on CD4+ T cells by affecting mRNA alternative splicing: priming for a synergistic effect on HIV-1 reservoir maintenance.
Yin Y, Zhang S, Luo H, Zhang X, Geng G, Li J, Guo X, Cai W, Li L, Liu C, Zhang H
The Journal of biological chemistry 2015 Jan 2;290(1):35-45
The Journal of biological chemistry 2015 Jan 2;290(1):35-45
Triptolide inhibits proliferation of Epstein-Barr virus-positive B lymphocytes by down-regulating expression of a viral protein LMP1.
Zhou H, Guo W, Long C, Wang H, Wang J, Sun X
Biochemical and biophysical research communications 2015 Jan 16;456(3):815-20
Biochemical and biophysical research communications 2015 Jan 16;456(3):815-20
siRNA-mediated knockdown against NUF2 suppresses pancreatic cancer proliferation in vitro and in vivo.
Hu P, Chen X, Sun J, Bie P, Zhang LD
Bioscience reports 2015 Jan 14;35(1)
Bioscience reports 2015 Jan 14;35(1)
Coumestrol inhibits carotid sinus baroreceptor activity by cAMP/PKA dependent nitric oxide release in anesthetized male rats.
Liu H, Wang L, Ma H, Guo R, Kang R, Han J, Dong Z
Biochemical pharmacology 2015 Jan 1;93(1):42-8
Biochemical pharmacology 2015 Jan 1;93(1):42-8
MicroRNA-103a inhibits gastric cancer cell proliferation, migration and invasion by targeting c-Myb.
Liang J, Liu X, Xue H, Qiu B, Wei B, Sun K
Cell proliferation 2015 Feb;48(1):78-85
Cell proliferation 2015 Feb;48(1):78-85
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
Li X, Liu X, Xu Y, He Y, Liu J, Xie M
International journal of oncology 2015 Feb;46(2):677-84
International journal of oncology 2015 Feb;46(2):677-84
KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma.
Guo Z, Liu J, Zhang L, Su B, Xing Y, He Q, Ci W, Li X, Zhou L
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Feb;36(2):1251-9
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Feb;36(2):1251-9
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Chen X, Meng Q, Wang C, Liu Q, Sun H, Huo X, Sun P, Yang X, Peng J, Liu K
Pharmaceutical research 2015 Feb;32(2):538-48
Pharmaceutical research 2015 Feb;32(2):538-48
Tumor protein D52-like 2 contributes to proliferation of breast cancer cells.
Yang M, Wang X, Jia J, Gao H, Chen P, Sha X, Wu S
Cancer biotherapy & radiopharmaceuticals 2015 Feb;30(1):1-7
Cancer biotherapy & radiopharmaceuticals 2015 Feb;30(1):1-7
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, Lei H, Tian Y, Li S, Liang P, Chen T, Liang C, Xu J, Li X, Huang Y, Yu X
Parasitology research 2015 Feb;114(2):659-70
Parasitology research 2015 Feb;114(2):659-70
Mechanism of action of gypenosides on type 2 diabetes and non-alcoholic fatty liver disease in rats.
He Q, Li JK, Li F, Li RG, Zhan GQ, Li G, Du WX, Tan HB
World journal of gastroenterology 2015 Feb 21;21(7):2058-66
World journal of gastroenterology 2015 Feb 21;21(7):2058-66
Multiple lysines combined in HIV-1 Vif determines the responsiveness to CBF-β.
Ai Y, Ma J
Biochemical and biophysical research communications 2015 Feb 13;457(3):385-90
Biochemical and biophysical research communications 2015 Feb 13;457(3):385-90
DNA damage and ER stress contribute to oblongifolin C-induced cell killing in Bax/Bak-deficient cells.
Xu W, Cheng M, Lao Y, Wang X, Wu J, Zhou L, Zhang Y, Xu H, Xu N
Biochemical and biophysical research communications 2015 Feb 13;457(3):300-6
Biochemical and biophysical research communications 2015 Feb 13;457(3):300-6
Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis.
Zhang H, Teng X, Liu Z, Zhang L, Liu Z
Journal of experimental & clinical cancer research : CR 2015 Feb 12;34(1):16
Journal of experimental & clinical cancer research : CR 2015 Feb 12;34(1):16
Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells.
Li X, Zhu F, Jiang J, Sun C, Wang X, Shen M, Tian R, Shi C, Xu M, Peng F, Guo X, Wang M, Qin R
Cancer letters 2015 Feb 1;357(1):219-230
Cancer letters 2015 Feb 1;357(1):219-230
Effects of atorvastatin on PDCD4/NF-κB/TNF-α signaling pathway during coronary microembolization of miniature pigs.
Su Q, Li L, Liu T, Wang J, Zhou Y, Liu Y
Experimental and molecular pathology 2015 Dec;99(3):564-9
Experimental and molecular pathology 2015 Dec;99(3):564-9
Growth hormone replacement therapy regulates microRNA-29a and targets involved in insulin resistance.
Galimov A, Hartung A, Trepp R, Mader A, Flück M, Linke A, Blüher M, Christ E, Krützfeldt J
Journal of molecular medicine (Berlin, Germany) 2015 Dec;93(12):1369-79
Journal of molecular medicine (Berlin, Germany) 2015 Dec;93(12):1369-79
Ultrasound-targeted microbubble destruction-mediated microRNA-21 transfection regulated PDCD4/NF-κB/TNF-α pathway to prevent coronary microembolization-induced cardiac dysfunction.
Su Q, Li L, Liu Y, Zhou Y, Wang J, Wen W
Gene therapy 2015 Dec;22(12):1000-6
Gene therapy 2015 Dec;22(12):1000-6
MicroRNA-214 suppresses the proliferation of human hepatocellular carcinoma cells by targeting E2F3.
Yang Y, Chang S, Zhao Z, Hou NI, He K, Wang X, Gao L, Wang L, Cai D, Guo BO, Tong D, Song T, Huang C
Oncology letters 2015 Dec;10(6):3779-3784
Oncology letters 2015 Dec;10(6):3779-3784
Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.
Liu C, Yue B, Yuan C, Zhao S, Fang C, Yu Y, Yan D
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):53-8
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):53-8
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC
Science (New York, N.Y.) 2015 Dec 11;350(6266):1391-6
Science (New York, N.Y.) 2015 Dec 11;350(6266):1391-6
Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma.
Zhang XF, Chao J, Pan QZ, Pan K, Weng DS, Wang QJ, Zhao JJ, He J, Liu Q, Jiang SS, Chen CL, Zhang HX, Xia JC
Oncotarget 2015 Dec 1;6(38):40920-33
Oncotarget 2015 Dec 1;6(38):40920-33
Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13.
Gao S, Zhou J, Liu N, Wang L, Gao Q, Wu Y, Zhao Q, Liu P, Wang S, Liu Y, Guo N, Shen Y, Wu Y, Yuan Z
Journal of molecular and cellular cardiology 2015 Aug;85:131-9
Journal of molecular and cellular cardiology 2015 Aug;85:131-9
The midgut of the silkmoth Bombyx mori is able to recycle molecules derived from degeneration of the larval midgut epithelium.
Franzetti E, Romanelli D, Caccia S, Cappellozza S, Congiu T, Rajagopalan M, Grimaldi A, de Eguileor M, Casartelli M, Tettamanti G
Cell and tissue research 2015 Aug;361(2):509-28
Cell and tissue research 2015 Aug;361(2):509-28
HSF4 promotes G1/S arrest in human lens epithelial cells by stabilizing p53.
Huang M, Li D, Huang Y, Cui X, Liao S, Wang J, Liu F, Li C, Gao M, Chen J, Tang Z, Li DW, Liu M
Biochimica et biophysica acta 2015 Aug;1853(8):1808-17
Biochimica et biophysica acta 2015 Aug;1853(8):1808-17
PARP-1 promotes autophagy via the AMPK/mTOR pathway in CNE-2 human nasopharyngeal carcinoma cells following ionizing radiation, while inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells.
Chen ZT, Zhao W, Qu S, Li L, Lu XD, Su F, Liang ZG, Guo SY, Zhu XD
Molecular medicine reports 2015 Aug;12(2):1868-76
Molecular medicine reports 2015 Aug;12(2):1868-76
Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression.
Peng W, Si S, Zhang Q, Li C, Zhao F, Wang F, Yu J, Ma R
Journal of experimental & clinical cancer research : CR 2015 Aug 8;34(1):79
Journal of experimental & clinical cancer research : CR 2015 Aug 8;34(1):79
Effects of JIP3 on epileptic seizures: Evidence from temporal lobe epilepsy patients, kainic-induced acute seizures and pentylenetetrazole-induced kindled seizures.
Wang Z, Chen Y, Lü Y, Chen X, Cheng L, Mi X, Xu X, Deng W, Zhang Y, Wang N, Li J, Li Y, Wang X
Neuroscience 2015 Aug 6;300:314-24
Neuroscience 2015 Aug 6;300:314-24
ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer.
Zhang P, Yu S, Li H, Liu C, Li J, Lin W, Gao A, Wang L, Gao W, Sun Y
FEBS letters 2015 Aug 4;589(17):2248-56
FEBS letters 2015 Aug 4;589(17):2248-56
Reduced USP39 expression inhibits malignant proliferation of medullary thyroid carcinoma in vitro.
An Y, Yang S, Guo K, Ma B, Wang Y
World journal of surgical oncology 2015 Aug 25;13(1):255
World journal of surgical oncology 2015 Aug 25;13(1):255
Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish.
Liu F, Chen J, Yu S, Raghupathy RK, Liu X, Qin Y, Li C, Huang M, Liao S, Wang J, Zou J, Shu X, Tang Z, Liu M
Human molecular genetics 2015 Aug 15;24(16):4648-59
Human molecular genetics 2015 Aug 15;24(16):4648-59
Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.
Pan X, Wang P, Luo J, Wang Z, Song Y, Ye J, Hou X
Endocrine 2015 Apr;48(3):834-47
Endocrine 2015 Apr;48(3):834-47
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Carr TD, Feehan RP, Hall MN, Rüegg MA, Shantz LM
Carcinogenesis 2015 Apr;36(4):487-97
Carcinogenesis 2015 Apr;36(4):487-97
Expression of RGC32 in human normal and preeclamptic placentas and its role in trophoblast cell invasion and migration.
Wang QJ, Song BF, Zhang YH, Ma YY, Shao QQ, Liu J, Qu X
Placenta 2015 Apr;36(4):350-6
Placenta 2015 Apr;36(4):350-6
Tumor protein D52-like 2 accelerates gastric cancer cell proliferation in vitro.
Xu J, Wang W, Zhu Z, Wei Z, Yang D, Cai Q
Cancer biotherapy & radiopharmaceuticals 2015 Apr;30(3):111-6
Cancer biotherapy & radiopharmaceuticals 2015 Apr;30(3):111-6
The expression and role of MEKK3 in renal clear cell carcinoma.
Lu H, Cao X, Chen Q, Chen L, Chen L, Gan M
Anatomical record (Hoboken, N.J. : 2007) 2015 Apr;298(4):727-34
Anatomical record (Hoboken, N.J. : 2007) 2015 Apr;298(4):727-34
Expression of TβR-2, Smad3 and Smad7 in the vaginal anterior wall of postpartum rats with stress urinary incontinence.
Wang H, Liu J, Zeng J, Zeng C, Zhou Y
Archives of gynecology and obstetrics 2015 Apr;291(4):869-76
Archives of gynecology and obstetrics 2015 Apr;291(4):869-76
Kaiso mainly locates in the nucleus in vivo and binds to methylated, but not hydroxymethylated DNA.
Qin S, Zhang B, Tian W, Gu L, Lu Z, Deng D
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2015 Apr;27(2):148-55
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2015 Apr;27(2):148-55
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Sun L, Song L, Wan Q, Wu G, Li X, Wang Y, Wang J, Liu Z, Zhong X, He X, Shen S, Pan X, Li A, Wang Y, Gao P, Tang H, Zhang H
Cell research 2015 Apr;25(4):429-44
Cell research 2015 Apr;25(4):429-44
Inhibition of 11β-HSD2 expression by triclosan via induction of apoptosis in human placental syncytiotrophoblasts.
Zhang N, Wang W, Li W, Liu C, Chen Y, Yang Q, Wang Y, Sun K
The Journal of clinical endocrinology and metabolism 2015 Apr;100(4):E542-9
The Journal of clinical endocrinology and metabolism 2015 Apr;100(4):E542-9
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
Li L, Dang Y, Zhang J, Yan W, Zhai W, Chen H, Li K, Tong L, Gao X, Amjad A, Ji L, Jing T, Jiang Z, Shi K, Yao L, Song D, Liu T, Yang X, Yang C, Cai X, Xu W, Huang Q, He J, Liu J, Chen T, Moses RE, Fu J, Xiao J, Li X
Nature communications 2015 Apr 24;6:6875
Nature communications 2015 Apr 24;6:6875
Methyl 3,4-dihydroxybenzoate promote rat cortical neurons survival and neurite outgrowth through the adenosine A2a receptor/PI3K/Akt signaling pathway.
Zhang Z, Cai L, Zhou X, Su C, Xiao F, Gao Q, Luo H
Neuroreport 2015 Apr 15;26(6):367-73
Neuroreport 2015 Apr 15;26(6):367-73
miR-367 promotes epithelial-to-mesenchymal transition and invasion of pancreatic ductal adenocarcinoma cells by targeting the Smad7-TGF-β signalling pathway.
Zhu Z, Xu Y, Zhao J, Liu Q, Feng W, Fan J, Wang P
British journal of cancer 2015 Apr 14;112(8):1367-75
British journal of cancer 2015 Apr 14;112(8):1367-75
Ku80 cooperates with CBP to promote COX-2 expression and tumor growth.
Xiao Y, Wang J, Qin Y, Xuan Y, Jia Y, Hu W, Yu W, Dai M, Li Z, Yi C, Zhao S, Li M, Du S, Cheng W, Xiao X, Chen Y, Wu T, Meng S, Yuan Y, Liu Q, Huang W, Guo W, Wang S, Deng W
Oncotarget 2015 Apr 10;6(10):8046-61
Oncotarget 2015 Apr 10;6(10):8046-61
BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs.
Liu Z, Wei P, Yang Y, Cui W, Cao B, Tan C, Yu B, Bi R, Xia K, Chen W, Wang Y, Zhang Y, Du X, Zhou X
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1752-63
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1752-63
Angelica Sinensis polysaccharides stimulated UDP-sugar synthase genes through promoting gene expression of IGF-1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity.
Wen Y, Li J, Tan Y, Qin J, Xie X, Wang L, Mei Q, Wang H, Magdalou J, Chen L
PloS one 2014;9(9):e107024
PloS one 2014;9(9):e107024
Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery.
Le Y, Liu S, Peng M, Tan C, Liao Q, Duan K, Ouyang W, Tong J
PloS one 2014;9(9):e106837
PloS one 2014;9(9):e106837
The tumor-suppressive microRNA-135b targets c-myc in osteoscarcoma.
Liu Z, Zhang G, Li J, Liu J, Lv P
PloS one 2014;9(7):e102621
PloS one 2014;9(7):e102621
Granulocyte colony-stimulating factor reduces fibrosis in a mouse model of chronic pancreatitis.
Lin WR, Yen TH, Lim SN, Perng MD, Lin CY, Su MY, Yeh CT, Chiu CT
PloS one 2014;9(12):e116229
PloS one 2014;9(12):e116229
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.
Shan X, Fu YS, Aziz F, Wang XQ, Yan Q, Liu JW
PloS one 2014;9(12):e115401
PloS one 2014;9(12):e115401
MicroRNA-33b suppresses migration and invasion by targeting c-Myc in osteosarcoma cells.
Xu N, Li Z, Yu Z, Yan F, Liu Y, Lu X, Yang W
PloS one 2014;9(12):e115300
PloS one 2014;9(12):e115300
MicroRNA-503 acts as a tumor suppressor in osteosarcoma by targeting L1CAM.
Chong Y, Zhang J, Guo X, Li G, Zhang S, Li C, Jiao Z, Shao M
PloS one 2014;9(12):e114585
PloS one 2014;9(12):e114585
Ginsenoside Rb1 prevents H2O2-induced HUVEC senescence by stimulating sirtuin-1 pathway.
Song Z, Liu Y, Hao B, Yu S, Zhang H, Liu D, Zhou B, Wu L, Wang M, Xiong Z, Wu C, Zhu J, Qian X
PloS one 2014;9(11):e112699
PloS one 2014;9(11):e112699
Autophagy is involved in the cardioprotection effect of remote limb ischemic postconditioning on myocardial ischemia/reperfusion injury in normal mice, but not diabetic mice.
Han Z, Cao J, Song D, Tian L, Chen K, Wang Y, Gao L, Yin Z, Fan Y, Wang C
PloS one 2014;9(1):e86838
PloS one 2014;9(1):e86838
Expression of annexin A7 and its clinical significance in differentiation and metastasis of gastric carcinoma.
Yuan HF, Li Y, Zhao Q, Fan LQ, Tan BB, Ye WH
International journal of clinical and experimental pathology 2014;7(10):6567-74
International journal of clinical and experimental pathology 2014;7(10):6567-74
MicroRNA-543 acts as an oncogene by targeting PAQR3 in hepatocellular carcinoma.
Yu L, Zhou L, Cheng Y, Sun L, Fan J, Liang J, Guo M, Liu N, Zhu L
American journal of cancer research 2014;4(6):897-906
American journal of cancer research 2014;4(6):897-906
Activation of the Nrf2-ARE pathway attenuates hyperglycemia-mediated injuries in mouse podocytes.
Wang C, Li C, Peng H, Ye Z, Zhang J, Liu X, Lou T
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;34(3):891-902
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;34(3):891-902
Intestinal mucosal barrier is injured by BMP2/4 via activation of NF-κB signals after ischemic reperfusion.
Chen K, Xie W, Luo B, Xiao W, Teitelbaum DH, Yang H, Zhang K, Zhang C
Mediators of inflammation 2014;2014:901530
Mediators of inflammation 2014;2014:901530
The possible role of the novel cytokines il-35 and il-37 in inflammatory bowel disease.
Li Y, Wang Y, Liu Y, Wang Y, Zuo X, Li Y, Lu X
Mediators of inflammation 2014;2014:136329
Mediators of inflammation 2014;2014:136329
MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis.
Cao XQ, Lu HS, Zhang L, Chen LL, Gan MF
Asian Pacific journal of cancer prevention : APJCP 2014;15(13):5271-6
Asian Pacific journal of cancer prevention : APJCP 2014;15(13):5271-6
The mitochondrial thioredoxin is required for liver development in zebrafish.
Zhang J, Cui X, Wang L, Liu F, Jiang T, Li C, Li D, Huang M, Liao S, Wang J, Chen J, Jia H, He J, Tang Z, Yin Z, Liu M
Current molecular medicine 2014;14(6):772-82
Current molecular medicine 2014;14(6):772-82
Novel approaches for the identification of nuclear transport receptor substrates.
Kimura M, Thakar K, Karaca S, Imamoto N, Kehlenbach RH
Methods in cell biology 2014;122:353-78
Methods in cell biology 2014;122:353-78
PARK7 protein translocating into spermatozoa mitochondria in Chinese asthenozoospermia.
Sun Y, Zhang WJ, Zhao X, Yuan RP, Jiang H, Pu XP
Reproduction (Cambridge, England) 2014 Sep;148(3):249-57
Reproduction (Cambridge, England) 2014 Sep;148(3):249-57
Galectin-3 is associated with a poor prognosis in primary hepatocellular carcinoma.
Jiang SS, Weng DS, Wang QJ, Pan K, Zhang YJ, Li YQ, Li JJ, Zhao JJ, He J, Lv L, Pan QZ, Xia JC
Journal of translational medicine 2014 Sep 27;12:273
Journal of translational medicine 2014 Sep 27;12:273
Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.
Bera S, Weinberg F, Ekoue DN, Ansenberger-Fricano K, Mao M, Bonini MG, Diamond AM
Cancer research 2014 Sep 15;74(18):5118-26
Cancer research 2014 Sep 15;74(18):5118-26
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
Li Y, Wang S, Wang Z, Qian X, Fan J, Zeng X, Sun Y, Song P, Feng M, Ju D
Nanotechnology 2014 Sep 12;25(36):365101
Nanotechnology 2014 Sep 12;25(36):365101
KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α.
Li X, Liu X, Xu Y, Liu J, Xie M, Ni W, Chen S
International journal of oncology 2014 Oct;45(4):1507-14
International journal of oncology 2014 Oct;45(4):1507-14
Knockdown of ubiquitin associated protein 2-like inhibits the growth and migration of prostate cancer cells.
Li D, Huang Y
Oncology reports 2014 Oct;32(4):1578-84
Oncology reports 2014 Oct;32(4):1578-84
si-RNA-Mediated Silencing of ADRBK1 Gene Attenuates Breast Cancer Cell Proliferation.
Zhang C, Chen X, Li Y, S W A H, Wu J, Shi X, Liu X, Kim S
Cancer biotherapy & radiopharmaceuticals 2014 Oct;29(8):303-9
Cancer biotherapy & radiopharmaceuticals 2014 Oct;29(8):303-9
Knockdown of ZFX suppresses renal carcinoma cell growth and induces apoptosis.
Fang Q, Fu WH, Yang J, Li X, Zhou ZS, Chen ZW, Pan JH
Cancer genetics 2014 Oct-Dec;207(10-12):461-6
Cancer genetics 2014 Oct-Dec;207(10-12):461-6
Synergistic contribution of SMAD signaling blockade and high localized cell density in the differentiation of neuroectoderm from H9 cells.
Liu C, Sun Y, Arnold J, Lu B, Guo S
Biochemical and biophysical research communications 2014 Oct 3;452(4):895-900
Biochemical and biophysical research communications 2014 Oct 3;452(4):895-900
A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.
Gingold JA, Fidalgo M, Guallar D, Lau Z, Sun Z, Zhou H, Faiola F, Huang X, Lee DF, Waghray A, Schaniel C, Felsenfeld DP, Lemischka IR, Wang J
Molecular cell 2014 Oct 2;56(1):140-52
Molecular cell 2014 Oct 2;56(1):140-52
MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes.
Wu J, Lv Q, He J, Zhang H, Mei X, Cui K, Huang N, Xie W, Xu N, Zhang Y
Cell communication and signaling : CCS 2014 Oct 11;12:66
Cell communication and signaling : CCS 2014 Oct 11;12:66
Mechanisms for U2AF to define 3' splice sites and regulate alternative splicing in the human genome.
Shao C, Yang B, Wu T, Huang J, Tang P, Zhou Y, Zhou J, Qiu J, Jiang L, Li H, Chen G, Sun H, Zhang Y, Denise A, Zhang DE, Fu XD
Nature structural & molecular biology 2014 Nov;21(11):997-1005
Nature structural & molecular biology 2014 Nov;21(11):997-1005
The role of microRNA-133b and its target gene FSCN1 in gastric cancer.
Guo L, Bai H, Zou D, Hong T, Liu J, Huang J, He P, Zhou Q, He J
Journal of experimental & clinical cancer research : CR 2014 Nov 30;33(1):99
Journal of experimental & clinical cancer research : CR 2014 Nov 30;33(1):99
Temporal phosphoproteomics to investigate the mechanotransduction of vascular smooth muscle cells in response to cyclic stretch.
Yang YC, Wang XD, Huang K, Wang L, Jiang ZL, Qi YX
Journal of biomechanics 2014 Nov 28;47(15):3622-9
Journal of biomechanics 2014 Nov 28;47(15):3622-9
Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.
Liu YM, Xia Y, Dai W, Han HY, Dong YX, Cai J, Zeng X, Luo FY, Yang T, Li YZ, Chen J, Guan J
BMC cancer 2014 Nov 28;14:889
BMC cancer 2014 Nov 28;14:889
SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma.
Guan Z, Zhang J, Wang J, Wang H, Zheng F, Peng J, Xu Y, Yan M, Liu B, Cui B, Huang Y, Liu Q
Molecular cancer 2014 Nov 26;13:257
Molecular cancer 2014 Nov 26;13:257
The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation.
Lao Y, Wan G, Liu Z, Wang X, Ruan P, Xu W, Xu D, Xie W, Zhang Y, Xu H, Xu N
Autophagy 2014 May;10(5):736-49
Autophagy 2014 May;10(5):736-49
Protective effects of dioscin against alcohol-induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53
Archives of toxicology 2014 Mar;88(3):739-53
Identification of rat respiratory mucosa stem cells and comparison of the early neural differentiation potential with the bone marrow mesenchymal stem cells in vitro.
Gao X, Zhang J, Zhang J, Zou H, Liu J
Cellular and molecular neurobiology 2014 Mar;34(2):257-68
Cellular and molecular neurobiology 2014 Mar;34(2):257-68
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis.
Gou LT, Dai P, Yang JH, Xue Y, Hu YP, Zhou Y, Kang JY, Wang X, Li H, Hua MM, Zhao S, Hu SD, Wu LG, Shi HJ, Li Y, Fu XD, Qu LH, Wang ED, Liu MF
Cell research 2014 Jun;24(6):680-700
Cell research 2014 Jun;24(6):680-700
MiR-214 promotes the alcohol-induced oxidative stress via down-regulation of glutathione reductase and cytochrome P450 oxidoreductase in liver cells.
Dong X, Liu H, Chen F, Li D, Zhao Y
Alcoholism, clinical and experimental research 2014 Jan;38(1):68-77
Alcoholism, clinical and experimental research 2014 Jan;38(1):68-77
The mechanisms of EGFR in the regulation of axon regeneration.
Xu MF, Zhou H, Hu CY, Liang YQ, Hu L, Chen D
Cell biochemistry and function 2014 Jan;32(1):101-5
Cell biochemistry and function 2014 Jan;32(1):101-5
Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway.
Wan G, Xie W, Liu Z, Xu W, Lao Y, Huang N, Cui K, Liao M, He J, Jiang Y, Yang BB, Xu H, Xu N, Zhang Y
Autophagy 2014 Jan;10(1):70-9
Autophagy 2014 Jan;10(1):70-9
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Gu GJ, Chen T, Zhou HM, Sun KX, Li J
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Effects of targeted modulation of miR-762 on expression of the IFITM5 gene in Saos-2 cells.
Mo X, Lu Y, Han J
Intractable & rare diseases research 2014 Feb;3(1):12-8
Intractable & rare diseases research 2014 Feb;3(1):12-8
ZNF16 (HZF1) promotes erythropoiesis and megakaryocytopoiesis via regulation of the c-KIT gene.
Chen J, Li XB, Su R, Song L, Wang F, Zhang JW
The Biochemical journal 2014 Feb 15;458(1):171-83
The Biochemical journal 2014 Feb 15;458(1):171-83
CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited.
Helsby MA, Leader PM, Fenn JR, Gulsen T, Bryant C, Doughton G, Sharpe B, Whitley P, Caunt CJ, James K, Pope AD, Kelly DH, Chalmers AD
BMC cell biology 2014 Feb 14;15:6
BMC cell biology 2014 Feb 14;15:6
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2014 Dec;5(12):3065-3075
Food & function 2014 Dec;5(12):3065-3075
C-type natriuretic peptide attenuates LPS-induced endothelial activation: involvement of p38, Akt, and NF-κB pathways.
Chen G, Zhao J, Yin Y, Wang B, Liu Q, Li P, Zhao L, Zhou H
Amino acids 2014 Dec;46(12):2653-63
Amino acids 2014 Dec;46(12):2653-63
[Excessive fluoride inducing calcium overload and apoptosis of ameloblasts].
Ying Z, Lin M, Jian L, Ming Z, Kaiqiang Z, Hefeng G
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 2014 Dec;32(6):542-6
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 2014 Dec;32(6):542-6
Ribosomal protein S15A augments human osteosarcoma cell proliferation in vitro.
Zhang C, Zhang T, Song E, Himaya SW, Chen X, Zheng L
Cancer biotherapy & radiopharmaceuticals 2014 Dec;29(10):451-6
Cancer biotherapy & radiopharmaceuticals 2014 Dec;29(10):451-6
MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells.
Shi W, Hou X, Peng H, Zhang L, Li Y, Gu Z, Jiang Q, Shi M, Ji Y, Jiang J
Virology journal 2014 Dec 30;11:227
Virology journal 2014 Dec 30;11:227
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Liu C, Lin JJ, Yang ZY, Tsai CC, Hsu JL, Wu YJ
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis.
Wen Y, Li J, Wang L, Tie K, Magdalou J, Chen L, Wang H
Arthritis research & therapy 2014 Dec 3;16(6):484
Arthritis research & therapy 2014 Dec 3;16(6):484
Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway.
Gupta SC, Singh R, Pochampally R, Watabe K, Mo YY
Oncotarget 2014 Dec 15;5(23):12070-82
Oncotarget 2014 Dec 15;5(23):12070-82
The RNA binding of protein A from Wuhan nodavirus is mediated by mitochondrial membrane lipids.
Qiu Y, Miao M, Wang Z, Liu Y, Yang J, Xia H, Li XF, Qin CF, Hu Y, Zhou X
Virology 2014 Aug;462-463:1-13
Virology 2014 Aug;462-463:1-13
P-glycoprotein expression in Perna viridis after exposure to Prorocentrum lima, a dinoflagellate producing DSP toxins.
Huang L, Wang J, Chen WC, Li HY, Liu JS, Tao Jiang, Yang WD
Fish & shellfish immunology 2014 Aug;39(2):254-62
Fish & shellfish immunology 2014 Aug;39(2):254-62
Rapamycin enhances cetuximab cytotoxicity by inhibiting mTOR-mediated drug resistance in mesenchymal hepatoma cells.
Chen W, Hu QD, Xia XF, Liang C, Liu H, Zhang Q, Ma T, Liang F, Liang TB
Cancer biology & therapy 2014 Aug;15(8):992-9
Cancer biology & therapy 2014 Aug;15(8):992-9
miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer.
Feng Y, Liu J, Kang Y, He Y, Liang B, Yang P, Yu Z
Journal of experimental & clinical cancer research : CR 2014 Aug 10;33(1):67
Journal of experimental & clinical cancer research : CR 2014 Aug 10;33(1):67
Inducible metabolic adaptation promotes mesenchymal stem cell therapy for ischemia: a hypoxia-induced and glycogen-based energy prestorage strategy.
Zhu H, Sun A, Zou Y, Ge J
Arteriosclerosis, thrombosis, and vascular biology 2014 Apr;34(4):870-6
Arteriosclerosis, thrombosis, and vascular biology 2014 Apr;34(4):870-6
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
Gong N, Xiao Q, Zhu B, Zhang CY, Wang YC, Fan H, Ma AN, Wang YX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5322-34
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5322-34
TAp63 suppress metastasis via miR-133b in colon cancer cells.
Lin CW, Li XR, Zhang Y, Hu G, Guo YH, Zhou JY, Du J, Lv L, Gao K, Zhang Y, Deng H
British journal of cancer 2014 Apr 29;110(9):2310-20
British journal of cancer 2014 Apr 29;110(9):2310-20
Expression and prognostic relevance of MET and phospho-BAD in non-small cell lung cancer.
Sun W, Ai T, Gao Y, Zhang Y, Cui J, Song L
OncoTargets and therapy 2013;6:1315-23
OncoTargets and therapy 2013;6:1315-23
Coculture of embryonic ventricular myocytes and mouse embryonic stem cell enhance intercellular signaling by upregulation of connexin43.
Li H, Tang M, Liang H, Li Y, Wang J, Song Y, Zheng Y, Xi J, Zhang J, Hescheler J, Zhu M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(1):53-63
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(1):53-63
MiR-138 induces renal carcinoma cell senescence by targeting EZH2 and is downregulated in human clear cell renal cell carcinoma.
Liang J, Zhang Y, Jiang G, Liu Z, Xiang W, Chen X, Chen Z, Zhao J
Oncology research 2013;21(2):83-91
Oncology research 2013;21(2):83-91
All-trans retinoic acid modulates mitogen-activated protein kinase pathway activation in human scleral fibroblasts through retinoic acid receptor beta.
Huo L, Cui D, Yang X, Gao Z, Trier K, Zeng J
Molecular vision 2013;19:1795-803
Molecular vision 2013;19:1795-803
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway.
Wei Y, Xu Y, Han X, Qi Y, Xu L, Xu Y, Yin L, Sun H, Liu K, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Sep;59:118-28
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Sep;59:118-28
Mutations in ABCB6 cause dyschromatosis universalis hereditaria.
Zhang C, Li D, Zhang J, Chen X, Huang M, Archacki S, Tian Y, Ren W, Mei A, Zhang Q, Fang M, Su Z, Yin Y, Liu D, Chen Y, Cui X, Li C, Yang H, Wang Q, Wang J, Liu M, Deng Y
The Journal of investigative dermatology 2013 Sep;133(9):2221-8
The Journal of investigative dermatology 2013 Sep;133(9):2221-8
miR-218 is downregulated and directly targets SH3GL1 in childhood medulloblastoma.
Shi J, Yang L, Wang T, Zhang J, Guo X, Huo X, Niu H
Molecular medicine reports 2013 Oct;8(4):1111-7
Molecular medicine reports 2013 Oct;8(4):1111-7
Emodin can induce K562 cells to erythroid differentiation and improve the expression of globin genes.
Ma YN, Chen MT, Wu ZK, Zhao HL, Yu HC, Yu J, Zhang JW
Molecular and cellular biochemistry 2013 Oct;382(1-2):127-36
Molecular and cellular biochemistry 2013 Oct;382(1-2):127-36
Clathrin heavy chain 1 is required for spindle assembly and chromosome congression in mouse oocytes.
Zhao J, Wang L, Zhou HX, Liu L, Lu A, Li GP, Schatten H, Liang CG
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2013 Oct;19(5):1364-73
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2013 Oct;19(5):1364-73
MicroRNA-124 protects neurons against apoptosis in cerebral ischemic stroke.
Sun Y, Gui H, Li Q, Luo ZM, Zheng MJ, Duan JL, Liu X
CNS neuroscience & therapeutics 2013 Oct;19(10):813-9
CNS neuroscience & therapeutics 2013 Oct;19(10):813-9
The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
Zeng L, Wan Y, Li D, Wu J, Shao M, Chen J, Hui L, Ji H, Zhu X
The Journal of biological chemistry 2013 Oct 18;288(42):30087-30093
The Journal of biological chemistry 2013 Oct 18;288(42):30087-30093
Bladder filling and voiding affect umbrella cell tight junction organization and function.
Carattino MD, Prakasam HS, Ruiz WG, Clayton DR, McGuire M, Gallo LI, Apodaca G
American journal of physiology. Renal physiology 2013 Oct 15;305(8):F1158-68
American journal of physiology. Renal physiology 2013 Oct 15;305(8):F1158-68
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Xu D, Yang W, Hu Y, Luo Z, Li J, Hou Y, Liu Y, Cai K
Colloids and surfaces. B, Biointerfaces 2013 Oct 1;110:225-35
Colloids and surfaces. B, Biointerfaces 2013 Oct 1;110:225-35
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Zhang S, Qi Y, Xu Y, Han X, Peng J, Liu K, Sun CK
Neurochemistry international 2013 Nov;63(5):522-32
Neurochemistry international 2013 Nov;63(5):522-32
Negative regulation of lncRNA GAS5 by miR-21.
Zhang Z, Zhu Z, Watabe K, Zhang X, Bai C, Xu M, Wu F, Mo YY
Cell death and differentiation 2013 Nov;20(11):1558-68
Cell death and differentiation 2013 Nov;20(11):1558-68
MicroRNA 23b regulates autophagy associated with radioresistance of pancreatic cancer cells.
Wang P, Zhang J, Zhang L, Zhu Z, Fan J, Chen L, Zhuang L, Luo J, Chen H, Liu L, Chen Z, Meng Z
Gastroenterology 2013 Nov;145(5):1133-1143.e12
Gastroenterology 2013 Nov;145(5):1133-1143.e12
PIAS1 negatively modulates virus triggered type I IFN signaling by blocking the DNA binding activity of IRF3.
Li R, Pan Y, Shi DD, Zhang Y, Zhang J
Antiviral research 2013 Nov;100(2):546-54
Antiviral research 2013 Nov;100(2):546-54
Induction of pluripotency in mouse somatic cells with lineage specifiers.
Shu J, Wu C, Wu Y, Li Z, Shao S, Zhao W, Tang X, Yang H, Shen L, Zuo X, Yang W, Shi Y, Chi X, Zhang H, Gao G, Shu Y, Yuan K, He W, Tang C, Zhao Y, Deng H
Cell 2013 May 23;153(5):963-75
Cell 2013 May 23;153(5):963-75
Membrane association of Wuhan nodavirus protein A is required for its ability to accumulate genomic RNA1 template.
Qiu Y, Wang Z, Liu Y, Qi N, Miao M, Si J, Xiang X, Cai D, Hu Y, Zhou X
Virology 2013 May 10;439(2):140-51
Virology 2013 May 10;439(2):140-51
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
Yao W, Fan W, Huang C, Zhong H, Chen X, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2013 Mar;67(2):140-5
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2013 Mar;67(2):140-5
The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage.
Zhang A, Zhou N, Huang J, Liu Q, Fukuda K, Ma D, Lu Z, Bai C, Watabe K, Mo YY
Cell research 2013 Mar;23(3):340-50
Cell research 2013 Mar;23(3):340-50
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.
Thakar K, Karaca S, Port SA, Urlaub H, Kehlenbach RH
Molecular & cellular proteomics : MCP 2013 Mar;12(3):664-78
Molecular & cellular proteomics : MCP 2013 Mar;12(3):664-78
MicroRNA-200a promotes anoikis resistance and metastasis by targeting YAP1 in human breast cancer.
Yu SJ, Hu JY, Kuang XY, Luo JM, Hou YF, Di GH, Wu J, Shen ZZ, Song HY, Shao ZM
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Mar 15;19(6):1389-99
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Mar 15;19(6):1389-99
The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL.
Wang P, Zhuang L, Zhang J, Fan J, Luo J, Chen H, Wang K, Liu L, Chen Z, Meng Z
Molecular oncology 2013 Jun;7(3):334-45
Molecular oncology 2013 Jun;7(3):334-45
The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms.
Cai Y, Cui W, Chen W, Wei P, Chi Y, Zhang P, Bi R, Zhou X
Cancer cell international 2013 Jun 7;13(1):57
Cancer cell international 2013 Jun 7;13(1):57
Umbilical cord blood cells regulate endogenous neural stem cell proliferation via hedgehog signaling in hypoxic ischemic neonatal rats.
Wang XL, Zhao YS, Hu MY, Sun YQ, Chen YX, Bi XH
Brain research 2013 Jun 26;1518:26-35
Brain research 2013 Jun 26;1518:26-35
The tumor-suppressive function of UNC5D and its repressed expression in renal cell carcinoma.
Lu D, Dong D, Zhou Y, Lu M, Pang XW, Li Y, Tian XJ, Zhang Y, Zhang J
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Jun 1;19(11):2883-92
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Jun 1;19(11):2883-92
Neuroprotective effect of resveratrol on ischemia/reperfusion injury in rats through TRPC6/CREB pathways.
Lin Y, Chen F, Zhang J, Wang T, Wei X, Wu J, Feng Y, Dai Z, Wu Q
Journal of molecular neuroscience : MN 2013 Jul;50(3):504-13
Journal of molecular neuroscience : MN 2013 Jul;50(3):504-13
Effects of sodium hydrosulfide on intestinal mucosal injury in a rat model of cardiac arrest and cardiopulmonary resuscitation.
Pan H, Chen D, Liu B, Xie X, Zhang J, Yang G
Life sciences 2013 Jul 19;93(1):24-29
Life sciences 2013 Jul 19;93(1):24-29
Methylation of Wnt antagonist genes: a useful prognostic marker for myelodysplastic syndrome.
Wang H, Fan R, Wang XQ, Wu DP, Lin GW, Xu Y, Li WY
Annals of hematology 2013 Jan;92(2):199-209
Annals of hematology 2013 Jan;92(2):199-209
PRL-3 activates NF-κB signaling pathway by interacting with RAP1.
Lian S, Meng L, Liu C, Xing X, Song Q, Dong B, Han Y, Yang Y, Peng L, Qu L, Shou C
Biochemical and biophysical research communications 2013 Jan 4;430(1):196-201
Biochemical and biophysical research communications 2013 Jan 4;430(1):196-201
Emodin regulates apoptotic pathway in human liver cancer cells.
Yu JQ, Bao W, Lei JC
Phytotherapy research : PTR 2013 Feb;27(2):251-7
Phytotherapy research : PTR 2013 Feb;27(2):251-7
Bifidobacterium infantis-mediated HSV-TK/GCV suicide gene therapy induces both extrinsic and intrinsic apoptosis in a rat model of bladder cancer.
Yin X, Yu B, Tang Z, He B, Ren J, Xiao X, Tang W
Cancer gene therapy 2013 Feb;20(2):77-81
Cancer gene therapy 2013 Feb;20(2):77-81
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Dong D, Zhang S, Yin L, Tang X, Xu Y, Han X, Qi Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Protective effect of autophagy inhibition on ischemia-reperfusion-induced injury of N2a cells.
Wang ZQ, Yang Y, Lu T, Luo P, Li J, Wu JP, Tang ZZ, Lu QP, Duan QH
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 Dec;33(6):810-816
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 Dec;33(6):810-816
The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.
Zhao H, Zhu L, Zhu Y, Cao J, Li S, Huang Q, Xu T, Huang X, Yan X, Zhu X
Nature cell biology 2013 Dec;15(12):1434-44
Nature cell biology 2013 Dec;15(12):1434-44
Neuroprotective effect of Danshensu derivatives as anti-ischaemia agents on SH-SY5Y cells and rat brain.
Seetapun S, Yaoling J, Wang Y, Zhu YZ
Bioscience reports 2013 Aug 30;33(4)
Bioscience reports 2013 Aug 30;33(4)
Cdc42-interacting protein-4 promotes TGF-Β1-induced epithelial-mesenchymal transition and extracellular matrix deposition in renal proximal tubular epithelial cells.
Bai S, Zeng R, Zhou Q, Liao W, Zhang Y, Xu C, Han M, Pei G, Liu L, Liu X, Yao Y, Xu G
International journal of biological sciences 2012;8(6):859-69
International journal of biological sciences 2012;8(6):859-69
Transcriptional regulation of PES1 expression by c-Jun in colon cancer.
Xie W, Feng Q, Su Y, Dong B, Wu J, Meng L, Qu L, Shou C
PloS one 2012;7(7):e42253
PloS one 2012;7(7):e42253
Distribution of bone morphogenetic protein receptors in human scleral fibroblasts cultured in vitro and human sclera.
Gao ZY, Huo LJ, Cui DM, Yang X, Wan WJ, Zeng JW
International journal of ophthalmology 2012;5(6):661-6
International journal of ophthalmology 2012;5(6):661-6
Alantolactone induces activation of apoptosis in human hepatoma cells.
Lei JC, Yu JQ, Yin Y, Liu YW, Zou GL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012 Sep;50(9):3313-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012 Sep;50(9):3313-9
Total flavonoids from Rosa Laevigata Michx fruit attenuates hydrogen peroxide induced injury in human umbilical vein endothelial cells.
Jia Y, Ji L, Zhang S, Xu L, Yin L, Li L, Zhao Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012 Sep;50(9):3133-41
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012 Sep;50(9):3133-41
Simvastatin reduces myocardial injury undergoing noncoronary artery cardiac surgery: a randomized controlled trial.
Almansob MA, Xu B, Zhou L, Hu XX, Chen W, Chang FJ, Ci HB, Yao JP, Xu YQ, Yao FJ, Liu DH, Zhang WB, Tang BY, Wang ZP, Ou JS
Arteriosclerosis, thrombosis, and vascular biology 2012 Sep;32(9):2304-13
Arteriosclerosis, thrombosis, and vascular biology 2012 Sep;32(9):2304-13
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Tu JB, Dong Q, Hu XY, Jiang F, Ma RZ, He LY, Yang ZQ
Journal of biochemical and molecular toxicology 2012 Sep;26(9):374-80
Journal of biochemical and molecular toxicology 2012 Sep;26(9):374-80
Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways.
Sun C, Wang D, Zheng W
Neuroreport 2012 Sep 12;23(13):768-73
Neuroreport 2012 Sep 12;23(13):768-73
New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.
Huang R, Yu M, Li CY, Zhan YQ, Xu WX, Xu F, Ge CH, Li W, Yang XM
Proteomics. Clinical applications 2012 Oct;6(9-10):467-75
Proteomics. Clinical applications 2012 Oct;6(9-10):467-75
Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation.
Yin JW, Liang Y, Park JY, Chen D, Yao X, Xiao Q, Liu Z, Jiang B, Fu Y, Bao M, Huang Y, Liu Y, Yan J, Zhu MS, Yang Z, Gao P, Tian B, Li D, Wang G
Genes & development 2012 Oct 1;26(19):2192-205
Genes & development 2012 Oct 1;26(19):2192-205
The 5' untranslated region of Apaf-1 mRNA directs translation under apoptosis conditions via a 5' end-dependent scanning mechanism.
Andreev DE, Dmitriev SE, Zinovkin R, Terenin IM, Shatsky IN
FEBS letters 2012 Nov 30;586(23):4139-43
FEBS letters 2012 Nov 30;586(23):4139-43
Differential expression profile of MicroRNAs during differentiation of cardiomyocytes exposed to polychlorinated biphenyls.
Zhu C, Yu ZB, Zhu JG, Hu XS, Chen YL, Qiu YF, Xu ZF, Qian LM, Han SP
International journal of molecular sciences 2012 Nov 28;13(12):15955-66
International journal of molecular sciences 2012 Nov 28;13(12):15955-66
A single centrifugation method for isolating fat droplets from cells and tissues.
Harris LLS, Shew TM, Skinner JR, Wolins NE
Journal of lipid research 2012 May;53(5):1021-1025
Journal of lipid research 2012 May;53(5):1021-1025
NOK/STYK1 has a strong tendency towards forming aggregates and colocalises with epidermal growth factor receptor in endosomes.
Ding X, Jiang QB, Li R, Chen S, Zhang S
Biochemical and biophysical research communications 2012 May 11;421(3):468-73
Biochemical and biophysical research communications 2012 May 11;421(3):468-73
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.
Gong K, Xie J, Yi H, Li W
The Biochemical journal 2012 May 1;443(3):735-46
The Biochemical journal 2012 May 1;443(3):735-46
Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death.
Yao JW, Liu J, Kong XZ, Zhang SG, Wang XH, Yu M, Zhan YQ, Li W, Xu WX, Tang LJ, Ge CH, Wang L, Li CY, Yang XM
Toxicology and applied pharmacology 2012 Mar 1;259(2):227-35
Toxicology and applied pharmacology 2012 Mar 1;259(2):227-35
A novel taspine derivative, HMQ1611, inhibits breast cancer cell growth via estrogen receptor α and EGF receptor signaling pathways.
Zhan Y, Zhang Y, Liu C, Zhang J, Smith WW, Wang N, Chen Y, Zheng L, He L
Cancer prevention research (Philadelphia, Pa.) 2012 Jun;5(6):864-73
Cancer prevention research (Philadelphia, Pa.) 2012 Jun;5(6):864-73
Silencing of FABP3 promotes apoptosis and induces mitochondrion impairment in embryonic carcinoma cells.
Shen YH, Song GX, Liu YQ, Sun W, Zhou LJ, Liu HL, Yang R, Sheng YH, Qian LM, Kong XQ
Journal of bioenergetics and biomembranes 2012 Jun;44(3):317-23
Journal of bioenergetics and biomembranes 2012 Jun;44(3):317-23
N-α-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression.
Xu H, Jiang B, Meng L, Ren T, Zeng Y, Wu J, Qu L, Shou C
Carcinogenesis 2012 Jun;33(6):1193-202
Carcinogenesis 2012 Jun;33(6):1193-202
Glycyl-tRNA synthetase specifically binds to the poliovirus IRES to activate translation initiation.
Andreev DE, Hirnet J, Terenin IM, Dmitriev SE, Niepmann M, Shatsky IN
Nucleic acids research 2012 Jul;40(12):5602-14
Nucleic acids research 2012 Jul;40(12):5602-14
Satb2 is required for dendritic arborization and soma spacing in mouse cerebral cortex.
Zhang L, Song NN, Chen JY, Huang Y, Li H, Ding YQ
Cerebral cortex (New York, N.Y. : 1991) 2012 Jul;22(7):1510-9
Cerebral cortex (New York, N.Y. : 1991) 2012 Jul;22(7):1510-9
MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia.
Zheng YS, Zhang H, Zhang XJ, Feng DD, Luo XQ, Zeng CW, Lin KY, Zhou H, Qu LH, Zhang P, Chen YQ
Oncogene 2012 Jan 5;31(1):80-92
Oncogene 2012 Jan 5;31(1):80-92
Activation of apoptosis by ethyl acetate fraction of ethanol extract of Dianthus superbus in HepG2 cell line.
Yu JQ, Yin Y, Lei JC, Zhang XQ, Chen W, Ding CL, Wu S, He XY, Liu YW, Zou GL
Cancer epidemiology 2012 Feb;36(1):e40-5
Cancer epidemiology 2012 Feb;36(1):e40-5
MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression.
Fei X, Qi M, Wu B, Song Y, Wang Y, Li T
FEBS letters 2012 Feb 17;586(4):392-7
FEBS letters 2012 Feb 17;586(4):392-7
Differential expression of oxidored nitro domain containing protein 1 (NOR1), in mouse tissues and in normal and cancerous human tissues.
Xiang B, Wang W, Li W, Li X, Li X, Li G
Gene 2012 Feb 1;493(1):18-26
Gene 2012 Feb 1;493(1):18-26
Glutamate attenuates IGF-1 receptor tyrosine phosphorylation in mouse brain: possible significance in ischemic brain damage.
Sun C, Meng Q, Zhang L, Wang H, Quirion R, Zheng W
Neuroscience research 2012 Dec;74(3-4):290-7
Neuroscience research 2012 Dec;74(3-4):290-7
Effects of SASH1 on melanoma cell proliferation and apoptosis in vitro.
Lin S, Zhang J, Xu J, Wang H, Sang Q, Xing Q, He L
Molecular medicine reports 2012 Dec;6(6):1243-8
Molecular medicine reports 2012 Dec;6(6):1243-8
Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.
Carr TD, DiGiovanni J, Lynch CJ, Shantz LM
Cancer prevention research (Philadelphia, Pa.) 2012 Dec;5(12):1394-404
Cancer prevention research (Philadelphia, Pa.) 2012 Dec;5(12):1394-404
NDR1/STK38 potentiates NF-κB activation by its kinase activity.
Shi DD, Shi H, Lu D, Li R, Zhang Y, Zhang J
Cell biochemistry and function 2012 Dec;30(8):664-70
Cell biochemistry and function 2012 Dec;30(8):664-70
Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways.
Zeng CW, Zhang XJ, Lin KY, Ye H, Feng SY, Zhang H, Chen YQ
Molecular pharmacology 2012 Apr;81(4):578-86
Molecular pharmacology 2012 Apr;81(4):578-86
Sulfated polysaccharide isolated from the sea cucumber Stichopus japonicus promotes neurosphere migration and differentiation via up-regulation of N-cadherin.
Sheng X, Li M, Song S, Zhang N, Wang Y, Liang H, Wang W, Ji A
Cellular and molecular neurobiology 2012 Apr;32(3):435-42
Cellular and molecular neurobiology 2012 Apr;32(3):435-42
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
Liu CI, Chen CC, Chen JC, Su JH, Huang HH, Chen JY, Wu YJ
Marine drugs 2011;9(7):1254-1272
Marine drugs 2011;9(7):1254-1272
Eos negatively regulates human γ-globin gene transcription during erythroid differentiation.
Yu HC, Zhao HL, Wu ZK, Zhang JW
PloS one 2011;6(7):e22907
PloS one 2011;6(7):e22907
miR-125b, a target of CDX2, regulates cell differentiation through repression of the core binding factor in hematopoietic malignancies.
Lin KY, Zhang XJ, Feng DD, Zhang H, Zeng CW, Han BW, Zhou AD, Qu LH, Xu L, Chen YQ
The Journal of biological chemistry 2011 Nov 4;286(44):38253-38263
The Journal of biological chemistry 2011 Nov 4;286(44):38253-38263
Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells.
Rao J, Xu DR, Zheng FM, Long ZJ, Huang SS, Wu X, Zhou WH, Huang RW, Liu Q
Journal of translational medicine 2011 May 19;9:71
Journal of translational medicine 2011 May 19;9:71
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
Sun Q, Chen X, Ma J, Peng H, Wang F, Zha X, Wang Y, Jing Y, Yang H, Chen R, Chang L, Zhang Y, Goto J, Onda H, Chen T, Wang MR, Lu Y, You H, Kwiatkowski D, Zhang H
Proceedings of the National Academy of Sciences of the United States of America 2011 Mar 8;108(10):4129-34
Proceedings of the National Academy of Sciences of the United States of America 2011 Mar 8;108(10):4129-34
The expression of a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is under the regulation of the HPG axis.
Zhou M, Wang Y, Qi S, Wang J, Zhang S
Endocrinology 2011 Jun;152(6):2311-20
Endocrinology 2011 Jun;152(6):2311-20
Biosynthesis and distribution of Lewis X- and Lewis Y-containing glycoproteins in the murine male reproductive system.
Wang C, Huang C, Gu Y, Zhou Y, Zhu Z, Zhang Y
Glycobiology 2011 Feb;21(2):225-34
Glycobiology 2011 Feb;21(2):225-34
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
Yin Y, Chen W, Tang C, Ding H, Jang J, Weng M, Cai Y, Zou G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011 Dec;49(12):3046-54
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011 Dec;49(12):3046-54
Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma.
Sun D, Zhou M, Kowolik CM, Trisal V, Huang Q, Kernstine KH, Lian F, Shen B
Melanoma research 2011 Aug;21(4):335-43
Melanoma research 2011 Aug;21(4):335-43
PTOV1 is associated with UCH-L1 and in response to estrogen stimuli during the mouse oocyte development.
Yao YW, Shi Y, Jia ZF, Jiang YH, Gu Z, Wang J, Aljofan M, Sun ZG
Histochemistry and cell biology 2011 Aug;136(2):205-15
Histochemistry and cell biology 2011 Aug;136(2):205-15
Single-walled carbon nanotube induction of rat aortic endothelial cell apoptosis: Reactive oxygen species are involved in the mitochondrial pathway.
Cheng WW, Lin ZQ, Wei BF, Zeng Q, Han B, Wei CX, Fan XJ, Hu CL, Liu LH, Huang JH, Yang X, Xi ZG
The international journal of biochemistry & cell biology 2011 Apr;43(4):564-72
The international journal of biochemistry & cell biology 2011 Apr;43(4):564-72
Role of Sema4C in TGF-β1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.
Zeng R, Han M, Luo Y, Li C, Pei G, Liao W, Bai S, Ge S, Liu X, Xu G
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011 Apr;26(4):1149-56
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011 Apr;26(4):1149-56
17β-Estradiol increased the expression of daintain/AIF-1 in RAW264.7 macrophages.
Yan DJ, Chen ZW
Bioscience, biotechnology, and biochemistry 2010;74(10):2103-5
Bioscience, biotechnology, and biochemistry 2010;74(10):2103-5
Combined effects of lapatinib and bortezomib in human epidermal receptor 2 (HER2)-overexpressing breast cancer cells and activity of bortezomib against lapatinib-resistant breast cancer cells.
Ma C, Niu X, Luo J, Shao Z, Shen K
Cancer science 2010 Oct;101(10):2220-6
Cancer science 2010 Oct;101(10):2220-6
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation.
Ye BQ, Geng ZH, Ma L, Geng JG
Journal of immunology (Baltimore, Md. : 1950) 2010 Nov 15;185(10):6294-305
Journal of immunology (Baltimore, Md. : 1950) 2010 Nov 15;185(10):6294-305
RNA interference inhibits hepatitis E virus mRNA accumulation and protein synthesis in vitro.
Huang F, Zhou J, Yang Z, Cui L, Zhang W, Yuan C, Yang S, Zhu J, Hua X
Veterinary microbiology 2010 May 19;142(3-4):261-7
Veterinary microbiology 2010 May 19;142(3-4):261-7
p,p'-DDE induces testicular apoptosis in prepubertal rats via the Fas/FasL pathway.
Shi YQ, Wang YP, Song Y, Li HW, Liu CJ, Wu ZG, Yang KD
Toxicology letters 2010 Mar 1;193(1):79-85
Toxicology letters 2010 Mar 1;193(1):79-85
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Chen W, Hou J, Yin Y, Jang J, Zheng Z, Fan H, Zou G
Biochemical pharmacology 2010 Jul 15;80(2):247-54
Biochemical pharmacology 2010 Jul 15;80(2):247-54
Melatonin protects N2a against ischemia/reperfusion injury through autophagy enhancement.
Guo Y, Wang J, Wang Z, Yang Y, Wang X, Duan Q
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2010 Feb;30(1):1-7
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2010 Feb;30(1):1-7
Toxicity of derivatives from semicarbazide-sensitive amine oxidase-mediated deamination of methylamine against Toxoplasma gondii after infection of differentiated 3T3-L1 cells.
Zhu S, Li QR, Du Y, Yang X, Fan JM, Dong ZM
Toxicology in vitro : an international journal published in association with BIBRA 2010 Apr;24(3):809-14
Toxicology in vitro : an international journal published in association with BIBRA 2010 Apr;24(3):809-14
Dual role of Ski in pancreatic cancer cells: tumor-promoting versus metastasis-suppressive function.
Wang P, Chen Z, Meng ZQ, Fan J, Luo JM, Liang W, Lin JH, Zhou ZH, Chen H, Wang K, Shen YH, Xu ZD, Liu LM
Carcinogenesis 2009 Sep;30(9):1497-506
Carcinogenesis 2009 Sep;30(9):1497-506
Construction of the Vero cell culture system that can produce infectious HCV particles.
Guo J, Yan R, Xu G, Li W, Zheng C
Molecular biology reports 2009 Jan;36(1):111-20
Molecular biology reports 2009 Jan;36(1):111-20
Oncoprotein BMI-1 induces the malignant transformation of HaCaT cells.
Wang Q, Li WL, You P, Su J, Zhu MH, Xie DF, Zhu HY, He ZY, Li JX, Ding XY, Wang X, Hu YP
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Proteomic alteration in lung tissue of rats exposed to cigarette smoke.
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Toxicology in vitro : an international journal published in association with BIBRA 2007 Sep;21(6):1095-103
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot of Hela cell with anti-GAPDH (10494-1-AP) at various dilutions.
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10494-1-AP(GAPDH antibody) at dilution of 1:5000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using GAPDH antibody 10494-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-GAPDH (IP:10494-1-AP, 3ug; Detection:10494-1-AP 1:3000) with A549 cells lysate 3500ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10494-1-AP(GAPDH antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GAPDH antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GAPDH. This antibody recognizes human,mouse,rat,pig antigen. The GAPDH antibody has been validated for the following applications: ELISA, IHC, WB, IP, IF, FC analysis.
