BS6884

antibody from Bioworld Technology, Inc
Targeting: GAPDH GAPD
Provider product page for BS6884
Western blot
Immunohistochemistry

Antibody data

Product number
BS6884 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FGR polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human FGR.
Description
Fgr is a member of the Src tyrosine kinase family. It has a membrane-associated amino-terminal domain that is highly divergent from other family members, internal conserved SH2 and SH3 domains and a highly conserved carboxy-terminal tyrosine kinase catalytic domain. Tyrosine 412 is located in the activation loop, and phosphorylation of this residue is critical for the activation of Fgr tyrosine kinase activity. c-Fgr is predominantly expressed in cells of hematopoietic origin including differentiated myeloid cells, NK and B cells. Fgr plays an important role in the signaling cascade from membrane receptors lacking intrinsic tyrosine kinase activity such as Bcr, FcR, and the integrin family of receptors. It was demonstrated that Fgr functions as a selective inhibitor of beta2 integrin-mediated signaling and Syk kinase function in monocytes.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GAPDH protein structure - BS6884 shown in red.