Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- M00710 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-GDNF Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for GDNF detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, WB. Reactive species: Human, Mouse, Rat GDNF information: Molecular Weight: 23720 MW; Subcellular Localization: Secreted ; Tissue Specificity: In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- ABDB-7
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Soluble dietary fiber and cellulose from Saccharina japonica by-product ameliorate Loperamide-induced constipation via modulating enteric neurotransmitters, short-chain fatty acids and gut microbiota.
Lipopolysaccharide inhibits the self-renewal of spermatogonial stem cells in vitro via downregulation of GDNF expression in Sertoli cells.
Cao J, Wang K, Li N, Zhang L, Qin L, He Y, Wang J, Qu C, Miao J
International journal of biological macromolecules 2023 Jan 31;226:1319-1331
International journal of biological macromolecules 2023 Jan 31;226:1319-1331
Lipopolysaccharide inhibits the self-renewal of spermatogonial stem cells in vitro via downregulation of GDNF expression in Sertoli cells.
Zhang X, Shi K, Li Y, Zhang H, Hao J
Reproductive toxicology (Elmsford, N.Y.) 2014 Jun;45:87-93
Reproductive toxicology (Elmsford, N.Y.) 2014 Jun;45:87-93
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