Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11760-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11760-1-AP, RRID:AB_2117500
- Product name
- HNRNPC antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HNRNPC antibody (Cat. #11760-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references N6-Methyladenosine reader HNRNPC-mediated downregulation of circITCH prevents miR-224-3p sequestering and contributes to tumorigenesis in nasopharyngeal carcinoma.
Loss of MIR503HG facilitates papillary renal cell carcinoma associated lymphatic metastasis by triggering NOTCH1/VEGFC signaling.
MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing.
Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment.
A splicing silencer in SMN2 intron 6 is critical in spinal muscular atrophy.
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells.
Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress.
LncRNA CALML3-AS1 modulated by m(6)A modification induces BTNL9 methylation to drive non-small-cell lung cancer progression.
m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
HNRNPC haploinsufficiency affects alternative splicing of intellectual disability-associated genes and causes a neurodevelopmental disorder.
Essential m(6)A Methylation Regulator HNRNPC Serves as a Targetable Biomarker for Papillary Renal Cell Carcinoma.
Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation.
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma.
Systematic analysis of the expression profile and prognostic significance of m6A regulators and PD-L1 in hepatocellular carcinoma.
Nuclear RNA transcript levels modulate nucleocytoplasmic distribution of ALS/FTD-associated protein FUS.
Alternative polyadenylation by sequential activation of distal and proximal PolyA sites.
Four m6A RNA Methylation Gene Signatures and Their Prognostic Values in Lung Adenocarcinoma.
METTL3 regulates heterochromatin in mouse embryonic stem cells.
Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis.
Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression.
hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.
M6A RNA Methylation Regulator HNRNPC Contributes to Tumorigenesis and Predicts Prognosis in Glioblastoma Multiforme.
Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.
An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells.
Zhou Q, Song W, Li X, Lin J, Zhu C, Cao L, Li W, Lin S
Environmental toxicology 2024 May;39(5):2893-2907
Environmental toxicology 2024 May;39(5):2893-2907
Loss of MIR503HG facilitates papillary renal cell carcinoma associated lymphatic metastasis by triggering NOTCH1/VEGFC signaling.
Wang Y, Zheng X, Huang W, Lu J, Hou N, Qi J, Ma J, Xue W, Zheng J, Zhai W
International journal of biological sciences 2023;19(10):3266-3284
International journal of biological sciences 2023;19(10):3266-3284
MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing.
Vital T, Wali A, Butler KV, Xiong Y, Foster JP 2nd, Marcel SS, McFadden AW, Nguyen VU, Bailey BM, Lamb KN, James LI, Frye SV, Mosely AL, Jin J, Pattenden SG, Davis IJ
Frontiers in oncology 2023;13:1099550
Frontiers in oncology 2023;13:1099550
Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment.
Deng X, Sun X, Hu Z, Wu Y, Zhou C, Sun J, Gao X, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23155
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23155
A splicing silencer in SMN2 intron 6 is critical in spinal muscular atrophy.
Wang L, Ji Y, Chen Y, Bai J, Gao P, Feng P
Human molecular genetics 2023 Mar 6;32(6):971-983
Human molecular genetics 2023 Mar 6;32(6):971-983
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
Chen QW, Cai QQ, Yang Y, Dong S, Liu YY, Chen ZY, Kang CL, Qi B, Dong YW, Wu W, Zhuang LP, Shen YH, Meng ZQ, Wu XZ
Clinical and translational medicine 2023 Jan;13(1):e1129
Clinical and translational medicine 2023 Jan;13(1):e1129
The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells.
Du P, Meng L, Liao X, Liu Y, Mo X, Gong M, Liao Y
Acta biochimica et biophysica Sinica 2023 Jan 25;55(1):103-116
Acta biochimica et biophysica Sinica 2023 Jan 25;55(1):103-116
Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress.
Ghanam AR, Ke S, Wang S, Elgendy R, Xie C, Wang S, Zhang R, Wei M, Liu W, Cao J, Zhang Y, Zhang Z, Xue T, Zheng Y, Song X
iScience 2023 Jan 20;26(1):105740
iScience 2023 Jan 20;26(1):105740
LncRNA CALML3-AS1 modulated by m(6)A modification induces BTNL9 methylation to drive non-small-cell lung cancer progression.
Zhang H, Wang SQ, Zhu JB, Wang LN, Lin H, Li LF, Cheng YD, Duan CJ, Zhang CF
Cancer gene therapy 2023 Dec;30(12):1649-1662
Cancer gene therapy 2023 Dec;30(12):1649-1662
m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
Wu Z, Zuo X, Zhang W, Li Y, Gui R, Leng J, Shen H, Pan B, Fan L, Li J, Jin H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
HNRNPC haploinsufficiency affects alternative splicing of intellectual disability-associated genes and causes a neurodevelopmental disorder.
Niggl E, Bouman A, Briere LC, Hoogenboezem RM, Wallaard I, Park J, Admard J, Wilke M, Harris-Mostert EDRO, Elgersma M, Bain J, Balasubramanian M, Banka S, Benke PJ, Bertrand M, Blesson AE, Clayton-Smith J, Ellingford JM, Gillentine MA, Goodloe DH, Haack TB, Jain M, Krantz I, Luu SM, McPheron M, Muss CL, Raible SE, Robin NH, Spiller M, Starling S, Sweetser DA, Thiffault I, Vetrini F, Witt D, Woods E, Zhou D, Genomics England Research Consortium, Undiagnosed Diseases Network, Elgersma Y, van Esbroeck ACM
American journal of human genetics 2023 Aug 3;110(8):1414-1435
American journal of human genetics 2023 Aug 3;110(8):1414-1435
Essential m(6)A Methylation Regulator HNRNPC Serves as a Targetable Biomarker for Papillary Renal Cell Carcinoma.
Wu J, Wei Y, Miao C, Wang S, Wang X, Wang Z
Journal of oncology 2022;2022:9411692
Journal of oncology 2022;2022:9411692
Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation.
Liu Y, Wang X, Zeng X, Wu Y, Liu X, Tan J, Li X
Open medicine (Warsaw, Poland) 2022;17(1):1183-1202
Open medicine (Warsaw, Poland) 2022;17(1):1183-1202
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma.
Li Y, Wang H, Wan J, Ma Q, Qi Y, Gu Z
Frontiers in oncology 2022;12:845931
Frontiers in oncology 2022;12:845931
Systematic analysis of the expression profile and prognostic significance of m6A regulators and PD-L1 in hepatocellular carcinoma.
Kong F, Wang K, Wang L
Discover oncology 2022 Nov 25;13(1):131
Discover oncology 2022 Nov 25;13(1):131
Nuclear RNA transcript levels modulate nucleocytoplasmic distribution of ALS/FTD-associated protein FUS.
Tsai YL, Mu YC, Manley JL
Scientific reports 2022 May 17;12(1):8180
Scientific reports 2022 May 17;12(1):8180
Alternative polyadenylation by sequential activation of distal and proximal PolyA sites.
Tang P, Yang Y, Li G, Huang L, Wen M, Ruan W, Guo X, Zhang C, Zuo X, Luo D, Xu Y, Fu XD, Zhou Y
Nature structural & molecular biology 2022 Jan;29(1):21-31
Nature structural & molecular biology 2022 Jan;29(1):21-31
Four m6A RNA Methylation Gene Signatures and Their Prognostic Values in Lung Adenocarcinoma.
Wang Y, Zhao X, Li J, Wang X, Hu W, Zhang X
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221085373
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221085373
METTL3 regulates heterochromatin in mouse embryonic stem cells.
Xu W, Li J, He C, Wen J, Ma H, Rong B, Diao J, Wang L, Wang J, Wu F, Tan L, Shi YG, Shi Y, Shen H
Nature 2021 Mar;591(7849):317-321
Nature 2021 Mar;591(7849):317-321
Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.
Khan M, Hou S, Azam S, Lei H
Nucleic acids research 2021 Jun 21;49(11):6420-6436
Nucleic acids research 2021 Jun 21;49(11):6420-6436
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis.
Park MK, Zhang L, Min KW, Cho JH, Yeh CC, Moon H, Hormaechea-Agulla D, Mun H, Ko S, Lee JW, Jathar S, Smith AS, Yao Y, Giang NT, Vu HH, Yan VC, Bridges MC, Kourtidis A, Muller F, Chang JH, Song SJ, Nakagawa S, Hirose T, Yoon JH, Song MS
Cell metabolism 2021 Dec 7;33(12):2380-2397.e9
Cell metabolism 2021 Dec 7;33(12):2380-2397.e9
Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression.
Lv W, Tan Y, Xiong M, Zhao C, Wang Y, Wu M, Wu Y, Zhang Q
Journal of translational medicine 2021 Dec 24;19(1):527
Journal of translational medicine 2021 Dec 24;19(1):527
hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.
Akinyemi AR, Li D, Zhang J, Liu Q
Neuroscience letters 2021 Apr 23;751:135824
Neuroscience letters 2021 Apr 23;751:135824
M6A RNA Methylation Regulator HNRNPC Contributes to Tumorigenesis and Predicts Prognosis in Glioblastoma Multiforme.
Wang LC, Chen SH, Shen XL, Li DC, Liu HY, Ji YL, Li M, Yu K, Yang H, Chen JJ, Qin CZ, Luo MM, Lin QX, Lv QL
Frontiers in oncology 2020;10:536875
Frontiers in oncology 2020;10:536875
Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.
Zhang Y, Liu X, Liu L, Li J, Hu Q, Sun R
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 22;26:e919644
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 22;26:e919644
An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells.
Su CC, Su JH, Lin JJ, Chen CC, Hwang WI, Huang HH, Wu YJ
Marine drugs 2011 Dec;9(12):2622-2642
Marine drugs 2011 Dec;9(12):2622-2642
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11760-1-AP(HNRNPC antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using HNRNPC antibody 11760-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line