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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 10045-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10045-1-Ig, RRID:AB_2232601
- Product name
- GRB7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GRB7 antibody (Cat. #10045-1-Ig) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ACOT8-mediated palmitate accumulation promotes M1 macrophage polarization in renal ischemia-reperfusion injury via activation of the cGAS-STING pathway.
TRIM36 Inhibits the Development of AOM/DSS-Induced Colitis-Associated Colorectal Cancer by Promoting the Ubiquitination and Degradation of GRB7.
GRB7-mediated enhancement of cell malignant characteristics induced by Helicobacter pylori infection.
TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
GRB7 Plays a Vital Role in Promoting the Progression and Mediating Immune Evasion of Ovarian Cancer.
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.
Zhang H, Liu X, Ji X, Zhang G, Wang B, Xiong F, Sun D, Wang C
International immunopharmacology 2026 Jun 1;178:116558
International immunopharmacology 2026 Jun 1;178:116558
TRIM36 Inhibits the Development of AOM/DSS-Induced Colitis-Associated Colorectal Cancer by Promoting the Ubiquitination and Degradation of GRB7.
Wu J, Yang Z, Chen X, Hou S, Li N, Chang Y, Yin J, Xu J
Molecular carcinogenesis 2025 Apr;64(4):668-679
Molecular carcinogenesis 2025 Apr;64(4):668-679
GRB7-mediated enhancement of cell malignant characteristics induced by Helicobacter pylori infection.
Zhao H, Chen S, Bai X, Zhang J, Liu S, Sun Z, Cao X, Wang J, Zhang Y, Li B, Ji X
Frontiers in microbiology 2024;15:1469953
Frontiers in microbiology 2024;15:1469953
TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
Wang G, Wu Y, Su Y, Qu N, Chen B, Zhou D, Yuan L, Yin M, Liu M, Zhou W
Journal of translational medicine 2024 Aug 7;22(1):745
Journal of translational medicine 2024 Aug 7;22(1):745
GRB7 Plays a Vital Role in Promoting the Progression and Mediating Immune Evasion of Ovarian Cancer.
Wen L, Hu W, Hou S, Luo C, Jin Y, Zeng Z, Zhang Z, Meng Y
Pharmaceuticals (Basel, Switzerland) 2024 Aug 7;17(8)
Pharmaceuticals (Basel, Switzerland) 2024 Aug 7;17(8)
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Zhang MX, Huang XY, Song Y, Xu WL, Li YL, Li C
Frontiers in pharmacology 2022;13:1103557
Frontiers in pharmacology 2022;13:1103557
Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.
Xu Q, Liu Z, Zhu ZQ, Fan Y, Chen R, Xie XH, Cheng M
Bioengineered 2021 Dec;12(2):12179-12190
Bioengineered 2021 Dec;12(2):12179-12190
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 10045-1-Ig(GRB7 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GRB7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GRB7. This antibody recognizes human, mouse antigen. The GRB7 antibody has been validated for the following applications: ELISA, WB, IP analysis.
