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- Antibody Data
- Antigen structure
- References [14]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 11405-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11405-1-AP, RRID:AB_2121207
- Product name
- HSP90AB1 antibody
- Antibody type
- Polyclonal
- Description
- HSP90AB1 antibody (Cat. #11405-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2.
GADD45β stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation.
Induction of autophagy and suppression of type I IFN secretion by CSFV.
A non-enveloped arbovirus released in lysosome-derived extracellular vesicles induces super-infection exclusion.
Osteoking improves OP rat by enhancing HSP90‑β expression.
Solvent-Induced Protein Precipitation for Drug Target Discovery on the Proteomic Scale.
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Hsp90 Chaperones Bluetongue Virus Proteins and Prevents Proteasomal Degradation.
Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Quantitative proteomic analysis of deer antler stem cells as a model of mammalian organ regeneration.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Phosphoproteome Characterization of Human Colorectal Cancer SW620 Cell-Derived Exosomes and New Phosphosite Discovery for C-HPP.
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
Zhang S, Huang W, Ren L, Ju X, Gong M, Rao J, Sun L, Li P, Ding Q, Wang J, Zhang QC
Cell research 2022 Jan;32(1):9-23
Cell research 2022 Jan;32(1):9-23
GADD45β stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation.
Dong Y, Ma N, Fan L, Yuan L, Wu Q, Gong L, Tao Z, Chen J, Ren J
Pharmacological research 2021 Nov;173:105879
Pharmacological research 2021 Nov;173:105879
Induction of autophagy and suppression of type I IFN secretion by CSFV.
Xie B, Zhao M, Song D, Wu K, Yi L, Li W, Li X, Wang K, Chen J
Autophagy 2021 Apr;17(4):925-947
Autophagy 2021 Apr;17(4):925-947
A non-enveloped arbovirus released in lysosome-derived extracellular vesicles induces super-infection exclusion.
Labadie T, Roy P
PLoS pathogens 2020 Oct;16(10):e1009015
PLoS pathogens 2020 Oct;16(10):e1009015
Osteoking improves OP rat by enhancing HSP90‑β expression.
Sun Y, Chen R, Zhu D, Shen ZQ, Zhao HB, Lee WH
International journal of molecular medicine 2020 May;45(5):1543-1553
International journal of molecular medicine 2020 May;45(5):1543-1553
Solvent-Induced Protein Precipitation for Drug Target Discovery on the Proteomic Scale.
Zhang X, Wang Q, Li Y, Ruan C, Wang S, Hu L, Ye M
Analytical chemistry 2020 Jan 7;92(1):1363-1371
Analytical chemistry 2020 Jan 7;92(1):1363-1371
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, Huang H, Li P, Fu S
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Hsp90 Chaperones Bluetongue Virus Proteins and Prevents Proteasomal Degradation.
Mohl BP, Roy P
Journal of virology 2019 Oct 15;93(20)
Journal of virology 2019 Oct 15;93(20)
Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Zhang LK, Wang B, Xin Q, Shang W, Shen S, Xiao G, Deng F, Wang H, Hu Z, Wang M
Journal of virology 2019 May 15;93(10)
Journal of virology 2019 May 15;93(10)
Quantitative proteomic analysis of deer antler stem cells as a model of mammalian organ regeneration.
Dong Z, Coates D, Liu Q, Sun H, Li C
Journal of proteomics 2019 Mar 20;195:98-113
Journal of proteomics 2019 Mar 20;195:98-113
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Phosphoproteome Characterization of Human Colorectal Cancer SW620 Cell-Derived Exosomes and New Phosphosite Discovery for C-HPP.
Guo J, Cui Y, Yan Z, Luo Y, Zhang W, Deng S, Tang S, Zhang G, He QY, Wang T
Journal of proteome research 2016 Nov 4;15(11):4060-4072
Journal of proteome research 2016 Nov 4;15(11):4060-4072
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Zhang L, Yu Z, Wang Y, Wang X, Zhang L, Wang C, Yue Q, Wang X, Deng S, Huo X, Tian X, Huang S, Zhang B, Ma X
Oncotarget 2016 Nov 22;7(47):76551-76564
Oncotarget 2016 Nov 22;7(47):76551-76564
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
Ding QH, Cheng Y, Chen WP, Zhong HM, Wang XH
European journal of pharmacology 2013 May 15;708(1-3):1-7
European journal of pharmacology 2013 May 15;708(1-3):1-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11405-1-AP(HSP90AB1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using HSP90AB1 antibody 11405-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11405-1-AP(HSP90AB1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
