ALX-804-811-C100

antibody from Enzo Life Sciences

Targeting: ANP32A C15orf1, I1PP2A, LANP, MAPM, mapmodulin, PHAPI, PP32

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ALX-804-811-C100

Provider

Enzo Life Sciences

Proper citation

Enzo Life Sciences Cat#ALX-804-811-C100, RRID:AB_2050620

Product name

Acidic nuclear phosphoprotein 32A (human) monoclonal antibody (RJ1)

Antibody type

Monoclonal

Antigen

Recombinant full length protein

Description

Protein G-affinity purified.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

RJ1

Vial size

100 μg

Storage

-20°C

Handling

Avoid freeze/thaw cycles.

References

Submitted references

Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis.

Martinvalet D, Zhu P, Lieberman J
Immunity 2005 Mar;22(3):355-70

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Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.

Fan Z, Beresford PJ, Oh DY, Zhang D, Lieberman J
Cell 2003 Mar 7;112(5):659-72

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Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A.

Fan Z, Beresford PJ, Zhang D, Xu Z, Novina CD, Yoshida A, Pommier Y, Lieberman J
Nature immunology 2003 Feb;4(2):145-53

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HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.

Fan Z, Beresford PJ, Zhang D, Lieberman J
Molecular and cellular biology 2002 Apr;22(8):2810-20

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Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks.

Beresford PJ, Zhang D, Oh DY, Fan Z, Greer EL, Russo ML, Jaju M, Lieberman J
The Journal of biological chemistry 2001 Nov 16;276(46):43285-93