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Learn55201-1-AP
antibody from Proteintech Group
Targeting: SET
2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 55201-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55201-1-AP, RRID:AB_10837360
- Product name
- SET/TAF-I antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SET/TAF-I antibody (Cat. #55201-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Orally Administered Rhamnan Sulfate from Monostroma nitidum Significantly Inhibits Melanoma Metastasis in Lungs and Aorta of Mice Implanted with B16 Cells.
Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells.
Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction.
ZNF331 Represses the Proliferation of Head and Neck Squamous Cell Carcinoma via Co-Repressor TRIM28.
Merkel Cell Polyomavirus targets SET/PP2A complex to promote cellular proliferation and migration.
PP2A activation overcomes leptomeningeal dissemination in group 3 medulloblastoma.
Novel PP2A-Activating Compounds in Neuroblastoma.
The Effects of Protein Phosphatase 2A Activation with Novel Tricyclic Sulfonamides on Hepatoblastoma.
Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.
A protocol to investigate the effects of lncRNAs on in vivo protein-protein interactions using proximity ligation assay.
A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression.
Venglustat Inhibits Protein N-Terminal Methyltransferase 1 in a Substrate-Competitive Manner.
Pre-Clinical Study Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Neuroblastoma.
MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer.
Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.
Overexpression of SET oncoprotein is associated with tumor progression and poor prognosis in human gastric cancer.
Overexpression of PP2A inhibitor SET oncoprotein is associated with tumor progression and poor prognosis in human non-small cell lung cancer.
SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-to-mesenchymal transition phenotype and cisplatin resistance in human lung cancer cell.
Reactivating PP2A by FTY720 as a novel therapy for AML with C-KIT tyrosine kinase domain mutation.
Hiramoto K, Imai M, Terasawa M, Suzuki K
Marine drugs 2026 Mar 29;24(4)
Marine drugs 2026 Mar 29;24(4)
Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells.
Di Crosta M, Ragone FC, Benedetti R, D'Orazi G, Santarelli R, Gilardini Montani MS, Cirone M
Biomedicines 2025 Sep 17;13(9)
Biomedicines 2025 Sep 17;13(9)
Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction.
Li XJ, Zhang MC, Li X, Guan LL, Liang YR, Hao EJ, Wang Y, Guo HM
Journal of medicinal chemistry 2025 Mar 13;68(5):5573-5596
Journal of medicinal chemistry 2025 Mar 13;68(5):5573-5596
ZNF331 Represses the Proliferation of Head and Neck Squamous Cell Carcinoma via Co-Repressor TRIM28.
Li J, Cheng H, Zhao Y, Wang Y, Gong C, Gong R, Li Y
Oral diseases 2025 Apr;31(4):1178-1188
Oral diseases 2025 Apr;31(4):1178-1188
Merkel Cell Polyomavirus targets SET/PP2A complex to promote cellular proliferation and migration.
Gupta P, Venuti A, Savoldy M, Harold A, Zito FA, Taverniti V, Romero-Medina MC, Galati L, Sirand C, Shahzad N, Shuda M, Gheit T, Accardi R, Tommasino M
Virology 2024 Sep;597:110143
Virology 2024 Sep;597:110143
PP2A activation overcomes leptomeningeal dissemination in group 3 medulloblastoma.
Nazam N, Erwin MH, Julson JR, Quinn CH, Beierle AM, Bownes LV, Stewart JE, Kang KD, Butey S, Mroczek-Musulman E, Ohlmeyer M, Beierle EA
The Journal of biological chemistry 2024 Nov;300(11):107892
The Journal of biological chemistry 2024 Nov;300(11):107892
Novel PP2A-Activating Compounds in Neuroblastoma.
Nazam N, Bownes LV, Julson JR, Quinn CH, Erwin MH, Marayati R, Markert HR, Shirley S, Stewart JE, Yoon KJ, Aye J, Ohlmeyer M, Beierle EA
Cancers 2024 Nov 15;16(22)
Cancers 2024 Nov 15;16(22)
The Effects of Protein Phosphatase 2A Activation with Novel Tricyclic Sulfonamides on Hepatoblastoma.
Bownes LV, Julson JR, Quinn CH, Hutchins SC, Erwin MH, Markert HR, Stewart JE, Mroczek-Musulman E, Aye J, Yoon KJ, Ohlmeyer M, Beierle EA
Journal of pediatric surgery 2023 Jun;58(6):1145-1154
Journal of pediatric surgery 2023 Jun;58(6):1145-1154
Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.
Deng Y, Dong G, Meng Y, Noinaj N, Huang R
Journal of medicinal chemistry 2023 Jan 26;66(2):1601-1615
Journal of medicinal chemistry 2023 Jan 26;66(2):1601-1615
A protocol to investigate the effects of lncRNAs on in vivo protein-protein interactions using proximity ligation assay.
Zhang L, He M, Wang P, Yu J, Li D
STAR protocols 2023 Dec 15;4(4):102757
STAR protocols 2023 Dec 15;4(4):102757
A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression.
Zhang L, Zhang J, Xuan X, Wu D, Yu J, Wang P, Yang X, Zhang J, Gan W, He M, Liu XM, Zhou J, Wang D, Gu W, Li D
Cell reports 2023 Aug 29;42(8):112833
Cell reports 2023 Aug 29;42(8):112833
Venglustat Inhibits Protein N-Terminal Methyltransferase 1 in a Substrate-Competitive Manner.
Dong G, Deng Y, Yasgar A, Yadav R, Talley D, Zakharov AV, Jain S, Rai G, Noinaj N, Simeonov A, Huang R
Journal of medicinal chemistry 2022 Sep 22;65(18):12334-12345
Journal of medicinal chemistry 2022 Sep 22;65(18):12334-12345
Pre-Clinical Study Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Neuroblastoma.
Bownes LV, Marayati R, Quinn CH, Beierle AM, Hutchins SC, Julson JR, Erwin MH, Stewart JE, Mroczek-Musulman E, Ohlmeyer M, Aye JM, Yoon KJ, Beierle EA
Cancers 2022 Apr 13;14(8)
Cancers 2022 Apr 13;14(8)
MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer.
Pan H, Pan Z, Guo F, Meng F, Zu L, Fan Y, Li Y, Li M, Du X, Zhang X, Shao Y, Wei M, Li X, Zhou Q
BMC cancer 2021 Nov 13;21(1):1218
BMC cancer 2021 Nov 13;21(1):1218
Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.
Mackie BD, Chen D, Dong G, Dong C, Parker H, Schaner Tooley CE, Noinaj N, Min J, Huang R
Journal of medicinal chemistry 2020 Sep 10;63(17):9512-9522
Journal of medicinal chemistry 2020 Sep 10;63(17):9512-9522
Overexpression of SET oncoprotein is associated with tumor progression and poor prognosis in human gastric cancer.
Yuan X, Zhang T, Zheng X, Zhang Y, Feng T, Liu P, Sun Z, Qin S, Liu X, Zhang L, Song J, Liu Y
Oncology reports 2017 Sep;38(3):1733-1741
Oncology reports 2017 Sep;38(3):1733-1741
Overexpression of PP2A inhibitor SET oncoprotein is associated with tumor progression and poor prognosis in human non-small cell lung cancer.
Liu H, Gu Y, Wang H, Yin J, Zheng G, Zhang Z, Lu M, Wang C, He Z
Oncotarget 2015 Jun 20;6(17):14913-25
Oncotarget 2015 Jun 20;6(17):14913-25
SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-to-mesenchymal transition phenotype and cisplatin resistance in human lung cancer cell.
Liu H, Gu Y, Yin J, Zheng G, Wang C, Zhang Z, Deng M, Liu J, Jia X, He Z
Cellular signalling 2014 Dec;26(12):2710-20
Cellular signalling 2014 Dec;26(12):2710-20
Reactivating PP2A by FTY720 as a novel therapy for AML with C-KIT tyrosine kinase domain mutation.
Yang Y, Huang Q, Lu Y, Li X, Huang S
Journal of cellular biochemistry 2012 Apr;113(4):1314-22
Journal of cellular biochemistry 2012 Apr;113(4):1314-22
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 55201-1-AP(SET antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 55201-1-AP(SET antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SET antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SET. This antibody recognizes human, mouse, rat antigen. The SET antibody has been validated for the following applications: ELISA, WB, IHC analysis.
