abx015900

antibody from Abbexa

Targeting: ITGB4 CD104

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx015900

Provider

Abbexa

Product name

Integrin Beta 4 (ITGb4) Antibody

Antibody type

Monoclonal

Description

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors.Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities.Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth.This gene encodes the integrin beta 4 subunit, a receptor for the laminins.This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma.Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia.Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.