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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Flow cytometry [1]
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- Product number
- 327802 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#327802, RRID:AB_893212
- Product name
- Purified anti-human CD104
- Antibody type
- Monoclonal
- Antigen
- CD104
- Description
- CD104 is a 205 kD type I transmembrane glycoprotein, known as integrin β4 chain or β4 integrin, that associates with integrin α6 (CD49f) forms α6/β4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on the proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells and a subset of pre-T cells. CD49f/CD104 is an adhesion receptor for laminins (especially laminin 5) and keratin filaments and is involved in the regulation of hemidesmosome formation and of cell proliferation and activation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human colon carcinoma cell line (HT29) stained with purified 58XB4, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated
