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- Antibody Data
- Antigen structure
- References [2]
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- Product number
- ABIN1889217 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin Receptor Substrate 1 (IRS1) (N-Term), (AA 106-122) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse IRS1(AA 106-122 WYQALLQLHNRAKAHHD), identical to the related rat sequence, and different from the related human sequence by one amino acid.
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term,AA 106-122
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2.
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.
Dearth RK, Cui X, Kim HJ, Kuiatse I, Lawrence NA, Zhang X, Divisova J, Britton OL, Mohsin S, Allred DC, Hadsell DL, Lee AV
Molecular and cellular biology 2006 Dec;26(24):9302-14
Molecular and cellular biology 2006 Dec;26(24):9302-14
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.
Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, Goldstein BJ, White MF
Nature 1991 Jul 4;352(6330):73-7
Nature 1991 Jul 4;352(6330):73-7
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