PAB12949

antibody from Abnova Corporation

Targeting: IRS1 HIRS-1

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB12949

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12949, RRID:AB_10553953

Product name

IRS1 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of IRS1.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Integration of growth factor and nutrient signaling: implications for cancer biology.

Shamji AF, Nghiem P, Schreiber SL
Molecular cell 2003 Aug;12(2):271-80

---

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB
Proceedings of the National Academy of Sciences of the United States of America 2001 Apr 10;98(8):4640-5

---

Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential.

Giovannone B, Scaldaferri ML, Federici M, Porzio O, Lauro D, Fusco A, Sbraccia P, Borboni P, Lauro R, Sesti G
Diabetes/metabolism research and reviews 2000 Nov-Dec;16(6):434-41

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of IRS1 in PC-3 cell lysate with IRS1 polyclonal antibody (Cat # PAB12949) at (A) 1, (B) 2 and (C) 4 ug/mL .

Immunocytochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunocytochemistry of IRS1 in P815 cells with IRS1 polyclonal antibody (Cat # PAB12949) at 2 ug/mL .

Validation comment

Immunocytochemistry