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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB18182 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18182, RRID:AB_10716794
- Product name
- IRS1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of IRS1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.
Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis.
Tzatsos A, Tsichlis PN
The Journal of biological chemistry 2007 Jun 22;282(25):18069-82
The Journal of biological chemistry 2007 Jun 22;282(25):18069-82
Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis.
Ma Z, Gibson SL, Byrne MA, Zhang J, White MF, Shaw LM
Molecular and cellular biology 2006 Dec;26(24):9338-51
Molecular and cellular biology 2006 Dec;26(24):9338-51
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of COS-7 cells, using IRS1 polyclonal antibody (Cat # PAB18182).Peptide "+" means "peptide blocking".
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS1 polyclonal antibody (Cat # PAB18182).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
