ABIN966413

antibody from antibodies-online

Targeting: IRS1 HIRS-1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966413

Provider

antibodies-online

Product name

anti-Insulin Receptor Substrate 1 (IRS1) (pSer307) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human IRS1 around the phosphorylation site of serine 307 (T-E-SP-I-T).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer307

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Inflammation and insulin resistance.

Shoelson SE, Lee J, Goldfine AB
The Journal of clinical investigation 2006 Jul;116(7):1793-801

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Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.

Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS
Proceedings of the National Academy of Sciences of the United States of America 2006 Jul 11;103(28):10741-6

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Activation of SOCS-3 by resistin.

Steppan CM, Wang J, Whiteman EL, Birnbaum MJ, Lazar MA
Molecular and cellular biology 2005 Feb;25(4):1569-75