ABIN967601

antibody from antibodies-online

Targeting: IRS1 HIRS-1

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN967601

Provider

antibodies-online

Product name

anti-Insulin Receptor Substrate 1 (IRS1) (pTyr896) antibody

Antibody type

Monoclonal

Antigen

Phosphorylated Human IRS-1 Peptide

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

pTyr896

Isotype

IgG

Antibody clone number

K9-211

Vial size

0.1 mg

Concentration

0.5 mg/ml

Storage

4°C

References

Submitted references

Positive and negative regulation of insulin signaling through IRS-1 phosphorylation.

Gual P, Le Marchand-Brustel Y, Tanti JF
Biochimie 2005 Jan;87(1):99-109

---

IRS proteins and the common path to diabetes.

White MF
American journal of physiology. Endocrinology and metabolism 2002 Sep;283(3):E413-22

---

Plant initiation factor 3 subunit composition resembles mammalian initiation factor 3 and has a novel subunit.

Burks EA, Bezerra PP, Le H, Gallie DR, Browning KS
The Journal of biological chemistry 2001 Jan 19;276(3):2122-31

---

IRS proteins and beta-cell function.

Burks DJ, White MF
Diabetes 2001 Feb;50 Suppl 1:S140-5

---

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.

Paz K, Liu YF, Shorer H, Hemi R, LeRoith D, Quan M, Kanety H, Seger R, Zick Y
The Journal of biological chemistry 1999 Oct 1;274(40):28816-22

---

Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor.

Ward CW, Gough KH, Rashke M, Wan SS, Tribbick G, Wang J
The Journal of biological chemistry 1996 Mar 8;271(10):5603-9