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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [21]
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- Validations
- Immunohistochemistry [1]
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- Product number
- sc-6216 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-6216, RRID:AB_648156
- Product name
- Anti-LMNB1
- Antibody type
- Polyclonal (Antigen purified)
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Goat
Submitted references Identification of a hormone-regulated dynamic nuclear actin network associated with estrogen receptor alpha in human breast cancer cell nuclei.
Regulation of notch1 signaling by nrf2: implications for tissue regeneration.
Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.
Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling.
Novel snail1 target proteins in human colon cancer identified by proteomic analysis.
REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells.
TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation.
Hypothyroidism enhances tumor invasiveness and metastasis development.
Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation.
Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades.
Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.
Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival.
Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha.
Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha.
Mutations of amino acids in the DNA-recognition domain of Epstein-Barr virus ZEBRA protein alter its sub-nuclear localization and affect formation of replication compartments.
Effects of lamin A/C, lamin B1, and viral US3 kinase activity on viral infectivity, virion egress, and the targeting of herpes simplex virus U(L)34-encoded protein to the inner nuclear membrane.
Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.
NFkappaB is persistently activated in continuously stimulated human neutrophils.
Herpes simplex virus type 1 infection induces activation and recruitment of protein kinase C to the nuclear membrane and increased phosphorylation of lamin B.
Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ
Ambrosino C, Tarallo R, Bamundo A, Cuomo D, Franci G, Nassa G, Paris O, Ravo M, Giovane A, Zambrano N, Lepikhova T, Jänne OA, Baumann M, Nyman TA, Cicatiello L, Weisz A
Molecular & cellular proteomics : MCP 2010 Jun;9(6):1352-67
Molecular & cellular proteomics : MCP 2010 Jun;9(6):1352-67
Regulation of notch1 signaling by nrf2: implications for tissue regeneration.
Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak MK, Misra V, Biswal S, Yamamoto M, Kensler TW
Science signaling 2010 Jul 13;3(130):ra52
Science signaling 2010 Jul 13;3(130):ra52
Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.
van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S
Molecular and cellular biology 2010 Jan;30(1):260-72
Molecular and cellular biology 2010 Jan;30(1):260-72
Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling.
Rajendrasozhan S, Chung S, Sundar IK, Yao H, Rahman I
American journal of physiology. Lung cellular and molecular physiology 2010 Feb;298(2):L197-209
American journal of physiology. Lung cellular and molecular physiology 2010 Feb;298(2):L197-209
Novel snail1 target proteins in human colon cancer identified by proteomic analysis.
Larriba MJ, Casado-Vela J, Pendás-Franco N, Peña R, García de Herreros A, Berciano MT, Lafarga M, Casal JI, Muñoz A
PloS one 2010 Apr 20;5(4):e10221
PloS one 2010 Apr 20;5(4):e10221
REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells.
Jørgensen HF, Terry A, Beretta C, Pereira CF, Leleu M, Chen ZF, Kelly C, Merkenschlager M, Fisher AG
Development (Cambridge, England) 2009 Mar;136(5):715-21
Development (Cambridge, England) 2009 Mar;136(5):715-21
TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation.
Pitulescu ME, Teichmann M, Luo L, Kessel M
BMC biochemistry 2009 Jun 10;10:16
BMC biochemistry 2009 Jun 10;10:16
Hypothyroidism enhances tumor invasiveness and metastasis development.
Martínez-Iglesias O, García-Silva S, Regadera J, Aranda A
PloS one 2009 Jul 29;4(7):e6428
PloS one 2009 Jul 29;4(7):e6428
Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation.
Corre S, Primot A, Baron Y, Le Seyec J, Goding C, Galibert MD
The Journal of biological chemistry 2009 Jul 10;284(28):18851-62
The Journal of biological chemistry 2009 Jul 10;284(28):18851-62
Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades.
Chen J, Rusnak M, Lombroso PJ, Sidhu A
The European journal of neuroscience 2009 Jan;29(2):287-306
The European journal of neuroscience 2009 Jan;29(2):287-306
Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.
Pereira CF, Terranova R, Ryan NK, Santos J, Morris KJ, Cui W, Merkenschlager M, Fisher AG
PLoS genetics 2008 Sep 5;4(9):e1000170
PLoS genetics 2008 Sep 5;4(9):e1000170
Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival.
Song J, So T, Croft M
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7240-8
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7240-8
Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha.
Vu HY, Juvekar A, Ghosh C, Ramaswami S, Le DH, Vancurova I
Archives of biochemistry and biophysics 2008 Jul 15;475(2):156-63
Archives of biochemistry and biophysics 2008 Jul 15;475(2):156-63
Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha.
Gehrig K, Cornell RB, Ridgway ND
Molecular biology of the cell 2008 Jan;19(1):237-47
Molecular biology of the cell 2008 Jan;19(1):237-47
Mutations of amino acids in the DNA-recognition domain of Epstein-Barr virus ZEBRA protein alter its sub-nuclear localization and affect formation of replication compartments.
Park R, Heston L, Shedd D, Delecluse HJ, Miller G
Virology 2008 Dec 20;382(2):145-62
Virology 2008 Dec 20;382(2):145-62
Effects of lamin A/C, lamin B1, and viral US3 kinase activity on viral infectivity, virion egress, and the targeting of herpes simplex virus U(L)34-encoded protein to the inner nuclear membrane.
Mou F, Wills EG, Park R, Baines JD
Journal of virology 2008 Aug;82(16):8094-104
Journal of virology 2008 Aug;82(16):8094-104
Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
Zwerger M, Herrmann H, Gaines P, Olins AL, Olins DE
Experimental hematology 2008 Aug;36(8):977-87
Experimental hematology 2008 Aug;36(8):977-87
SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.
Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I
American journal of respiratory and critical care medicine 2008 Apr 15;177(8):861-70
American journal of respiratory and critical care medicine 2008 Apr 15;177(8):861-70
NFkappaB is persistently activated in continuously stimulated human neutrophils.
Miskolci V, Rollins J, Vu HY, Ghosh CC, Davidson D, Vancurova I
Molecular medicine (Cambridge, Mass.) 2007 Mar-Apr;13(3-4):134-42
Molecular medicine (Cambridge, Mass.) 2007 Mar-Apr;13(3-4):134-42
Herpes simplex virus type 1 infection induces activation and recruitment of protein kinase C to the nuclear membrane and increased phosphorylation of lamin B.
Park R, Baines JD
Journal of virology 2006 Jan;80(1):494-504
Journal of virology 2006 Jan;80(1):494-504
Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ
Jalila Adnane, Francisco A Bizouarn, Zhi Chen, Junko Ohkanda, Andrew D Hamilton, Teresita Munoz-Antonia, Saïd M Sebti
Oncogene 2000 Nov;19(48):5525-5533
Oncogene 2000 Nov;19(48):5525-5533
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Supportive validation
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- Main image
- Experimental details
- Immunohistochemical staining of human small intestine shows nuclear membranous positivity in glandular cells.
- Validation comment
- Staining pattern consistent with experimental and/or bioinformatic data.
